Mitchell J. Weiss - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, ... Weiss MJ, et al. Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics. PMID 35650318 DOI: 10.1038/s41588-022-01112-0  0.651
2022 Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, ... Weiss MJ, et al. Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics. PMID 35618846 DOI: 10.1038/s41588-022-01076-1  0.701
2020 Bhoopalan SV, Huang LJ, Weiss MJ. Erythropoietin regulation of red blood cell production: from bench to bedside and back. F1000research. 9. PMID 32983414 DOI: 10.12688/F1000Research.26648.1  0.323
2020 Demirci S, Zeng J, Wu Y, Uchida N, Shen AH, Pellin D, Gamer J, Yapundich M, Drysdale C, Bonanno J, Bonifacino AC, Krouse A, Linde NS, Engels T, Donahue RE, ... ... Weiss M, et al. BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity. The Journal of Clinical Investigation. PMID 32897878 DOI: 10.1172/Jci140189  0.396
2020 Xiang G, Keller CA, Heuston EF, Giardine BM, An L, Wixom AQ, Miller A, Cockburn A, Sauria MEG, Weaver K, Lichtenberg J, Göttgens B, Li Q, Bodine D, Mahony S, ... ... Weiss MJ, et al. An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis. Genome Research. PMID 32132109 DOI: 10.1101/Gr.255760.119  0.331
2019 Hardison RC, Zhang Y, Keller CA, Xiang G, Heuston EF, An L, Lichtenberg J, Giardine BM, Bodine D, Mahony S, Li Q, Yue F, Weiss MJ, Blobel GA, Taylor J, et al. Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells. Iubmb Life. PMID 31769130 DOI: 10.1002/Iub.2195  0.404
2019 Métais JY, Doerfler PA, Mayuranathan T, Bauer DE, Fowler SC, Hsieh MM, Katta V, Keriwala S, Lazzarotto CR, Luk K, Neel MD, Perry SS, Peters ST, Porter SN, Ryu BY, ... ... Weiss MJ, et al. Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. Blood Advances. 3: 3379-3392. PMID 31698466 DOI: 10.1182/Bloodadvances.2019000820  0.398
2019 Lechauve C, Keith J, Khandros E, Fowler S, Mayberry K, Freiwan A, Thom CS, Delbini P, Romero EB, Zhang J, Motta I, Tillman H, Cappellini MD, Kundu M, Weiss MJ. The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia. Science Translational Medicine. 11. PMID 31434755 DOI: 10.1126/Scitranslmed.Aav4881  0.682
2019 Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross SJ, Kang G, Ma Z, Condori J, Dowdy J, Triplett B, Li C, Maron G, Aldave Becerra JC, Church JA, Dokmeci E, ... ... Weiss MJ, et al. Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. The New England Journal of Medicine. 380: 1525-1534. PMID 30995372 DOI: 10.1056/Nejmoa1815408  0.303
2019 Bhoopalan SV, Han M, Ellis S, Lesmana H, Estepp JH, Jang Y, Weiss MJ, Wlodarski MW. Disease Modeling and Phenotype Rescue Using Inducible Pluripotent Stem Cells from Patients with Diamond-Blackfan Anemia Blood. 134: 2496-2496. DOI: 10.1182/Blood-2019-131354  0.39
2019 Metais J, Doerfler PA, Mayuranathan T, Bauer DE, Fowler S, Hsieh M, Katta V, Keriwala S, Lazzarotto C, Luk K, Neel M, Perry S, Porter S, Ryu BY, Sharma A, ... ... Weiss MJ, et al. CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies Blood. 134: 2066-2066. DOI: 10.1182/Blood-2019-131318  0.415
2019 Demirci S, Zeng J, Wu Y, Uchida N, Gamer J, Yapundich M, Drysdale C, Bonifacino AC, Krouse AE, Linde NS, Donahue RE, Shen AH, Haro-Mora JJ, Leonard A, Nassehi T, ... ... Weiss MJ, et al. Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing Blood. 134: 4632-4632. DOI: 10.1182/Blood-2019-129394  0.359
2019 Leonard A, Uchida N, Stroncek DF, Panch SR, West K, Molloy EG, Hughes T, Hauffe S, Taylor T, Fitzhugh CD, Hankins JS, Wilson M, Sharma A, Tsai SQ, Weiss MJ, et al. Safe and Efficient Peripheral Blood Stem Cell Collection in Patients with Sickle Cell Disease Using Plerixafor Blood. 134: 1964-1964. DOI: 10.1182/Blood-2019-126091  0.308
2019 Doerfler P, Feng R, Porter S, Li Y, Crossley M, Cheng Y, Pruett-Miller S, Weiss M. FUNCTIONALLY DISTINCT UTILIZATION OF CIS-REGULATORY ELEMENTS IN HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN Experimental Hematology. 76: S64. DOI: 10.1016/J.Exphem.2019.06.350  0.354
2018 Bhang DH, Kim BJ, Kim BG, Schadler K, Baek KH, Kim YH, Hsiao W, Ding BS, Rafii S, Weiss MJ, Chou ST, Kolon TF, Ginsberg JP, Ryu BY, Ryeom S. Testicular endothelial cells are a critical population in the germline stem cell niche. Nature Communications. 9: 4379. PMID 30348976 DOI: 10.1038/S41467-018-06881-Z  0.348
2018 Lechauve C, Butcher JT, Freiwan A, Biwer LA, Keith JM, Good ME, Ackerman H, Tillman HS, Kiger L, Isakson BE, Weiss MJ. Endothelial cell α-globin and its molecular chaperone α-hemoglobin-stabilizing protein regulate arteriolar contractility. The Journal of Clinical Investigation. PMID 30295646 DOI: 10.1172/Jci99933  0.319
2018 Zhang Y, Paikari A, Sumazin P, Ginter Summarell CC, Crosby JR, Boerwinkle E, Weiss MJ, Sheehan VA. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells. Blood. PMID 29884740 DOI: 10.1182/Blood-2017-11-814335  0.414
2018 Xu P, Scott DC, Tang X, Yao Y, Wang Y, Bi W, Palmer LE, Feng R, Alpi AF, Li C, Cheng Y, Schulman BA, Weiss MJ. FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1 Blood. 132: 529-529. DOI: 10.1182/Blood-2018-99-117362  0.443
2018 Labuhn M, Perkins K, Papaemmanuil E, Garnett C, Matzk S, Amstislavskiy V, Metzner M, Kennedy A, Scheer C, Yoshida K, Schwarzer A, Crispino JD, Taub JW, Weiss MJ, Ito E, et al. Modelling the Progression of a Preleukemic Stage to Overt Leukemia in Children with Down Syndrome Blood. 132: 543-543. DOI: 10.1182/Blood-2018-99-116661  0.359
2018 Feng R, Doerfler PA, Yao Y, Tang X, Wang Y, Li C, Root DE, Cheng Y, Weiss MJ. The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation Blood. 132: 410-410. DOI: 10.1182/Blood-2018-99-115589  0.412
2018 Paikari A, Mi T, Zhang Y, Rampersaud E, Kang G, Wu G, Hankins JS, Estepp JH, Sumazin P, Weiss MJ, Sheehan VA. Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Induces Fetal Hemoglobin in Hematopoietic Stem and Progenitor Cells from Patients with Sickle Cell Anemia Blood. 132: 722-722. DOI: 10.1182/Blood-2018-99-115383  0.367
2018 Lechauve C, Keith J, Khandros E, Fowler S, Mayberry K, Freiwan A, Thom C, Zhang J, Tillman H, Kundu M, Motta I, Cappellini MD, Weiss MJ. Activation of ULK1 Kinase Mediates Clearance of Free Alpha-Globin in Human Beta-Thalassemic Erythroblasts Blood. 132: 411-411. DOI: 10.1182/Blood-2018-99-113901  0.696
2017 Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, et al. UBE2O remodels the proteome during terminal erythroid differentiation. Science (New York, N.Y.). 357. PMID 28774900 DOI: 10.1126/Science.Aan0218  0.347
2017 Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross S, Ma Z, Dowdy J, Triplett B, Weiss MJ, Ryu BY, Dokmeci E, Aldave JC, Ravin SSD, Youngblood B, Long-Boyle JR, et al. Interim Results from a Phase I/II Clinical Gene Therapy Study for Newly Diagnosed Infants with X-Linked Severe Combined Immunodeficiency Using a Safety-Modified Lentiviral Vector and Targeted Reduced Exposure to Busulfan Blood. 130: 523-523. DOI: 10.1182/Blood.V130.Suppl_1.523.523  0.301
2016 Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition. Nature Medicine. PMID 27525524 DOI: 10.1038/Nm.4170  0.377
2016 Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, et al. The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. Nature Communications. 7: 12353. PMID 27507172 DOI: 10.1038/Ncomms12353  0.35
2016 Weiss MJ, Mullighan C. Perspective: Welcoming a New Age for Gene Therapy in Hematology. Blood. PMID 27053534 DOI: 10.1182/Blood-2016-03-678714  0.347
2016 Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Unlinking an lncRNA from Its Associated cis Element. Molecular Cell. PMID 27041223 DOI: 10.1016/J.Molcel.2016.02.029  0.363
2016 Lechauve C, Butcher J, Freiwan A, Good M, Frase S, Tillman H, Isakson B, Weiss MJ. Endothelial Cell-Expressed α Hemoglobin and Its Molecular Chaperone Ahsp Modulate Arterial Vascular Reactivity Blood. 128: 557-557. DOI: 10.1182/Blood.V128.22.557.557  0.375
2016 Paralkar VR, Palmer L, Xu P, Lechauve C, Zhao G, Yao Y, Wu G, Luan J, Weiss MJ. Erythroid miRNA-144/451 Binds Many mRNAs but Regulates Only a Small Subset Blood. 128: 1198-1198. DOI: 10.1182/Blood.V128.22.1198.1198  0.319
2015 Pestina TI, Hargrove PW, Zhao H, Mead PE, Smeltzer MP, Weiss MJ, Wilber A, Persons DA. Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells. Molecular Therapy. Methods & Clinical Development. 2: 15045. PMID 26665131 DOI: 10.1038/Mtm.2015.45  0.369
2015 Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, ... Weiss MJ, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. PMID 26607381 DOI: 10.1016/J.Stem.2015.09.015  0.367
2015 Ghanem LR, Kromer A, Silverman IM, Chatterji P, Traxler E, Penzo-Mendez A, Weiss MJ, Stanger BZ, Liebhaber SA. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Molecular and Cellular Biology. 36: 304-19. PMID 26527618 DOI: 10.1128/Mcb.00936-15  0.399
2015 Ge J, Apicella M, Mills JA, Garçon L, French DL, Weiss MJ, Bessler M, Mason PJ. Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia. Plos One. 10: e0134878. PMID 26258650 DOI: 10.1371/Journal.Pone.0134878  0.403
2015 Dogan N, Wu W, Morrissey CS, Chen KB, Stonestrom A, Long M, Keller CA, Cheng Y, Jain D, Visel A, Pennacchio LA, Weiss MJ, Blobel GA, Hardison RC. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics & Chromatin. 8: 16. PMID 25984238 DOI: 10.1186/S13072-015-0009-5  0.317
2015 Noh JY, Gandre-Babbe S, Wang Y, Hayes V, Yao Y, Gadue P, Sullivan SK, Chou ST, Machlus KR, Italiano JE, Kyba M, Finkelstein D, Ulirsch JC, Sankaran VG, French DL, ... ... Weiss MJ, et al. Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells. The Journal of Clinical Investigation. 125: 2369-74. PMID 25961454 DOI: 10.1172/Jci77670  0.399
2015 Jain D, Mishra T, Giardine BM, Keller CA, Morrissey CS, Magargee S, Dorman CM, Long M, Weiss MJ, Hardison RC. Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system. Genomics Data. 4: 1-7. PMID 25729644 DOI: 10.1016/J.Gdata.2015.01.008  0.39
2015 Byrska-Bishop M, VanDorn D, Campbell AE, Betensky M, Arca PR, Yao Y, Gadue P, Costa FF, Nemiroff RL, Blobel GA, French DL, Hardison RC, Weiss MJ, Chou ST. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus. The Journal of Clinical Investigation. 125: 993-1005. PMID 25621499 DOI: 10.1172/Jci75714  0.409
2015 Antony-Debré I, Manchev VT, Balayn N, Bluteau D, Tomowiak C, Legrand C, Langlois T, Bawa O, Tosca L, Tachdjian G, Leheup B, Debili N, Plo I, Mills JA, French DL, ... Weiss MJ, et al. Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia. Blood. 125: 930-40. PMID 25490895 DOI: 10.1182/Blood-2014-06-585513  0.36
2015 Traxler E, Yao Y, Li C, Grevet J, Huang P, Wright S, Blobel GA, Weiss MJ. Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts Blood. 126: 640-640. DOI: 10.1182/Blood.V126.23.640.640  0.406
2015 Paralkar VR, Taborda C, Yao Y, Prasad R, Luan J, Hardison RC, Blobel GA, Weiss MJ. A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function Blood. 126: 1175-1175. DOI: 10.1182/Blood.V126.23.1175.1175  0.391
2015 Steinberg Shemer O, Byrska-Bishop M, Ulirsch JC, Abdulmalik O, Yao Y, Kim AR, Gadue P, Kingsley PD, French D, Hardison RC, Palis J, Sankaran VG, Weiss MJ. Temporally Distinct Developmental Waves of Erythropoiesis from Human Pluripotent Stem Cells Blood. 126: 1170-1170. DOI: 10.1182/Blood.V126.23.1170.1170  0.363
2014 Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ. Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis. Genome Research. 24: 1932-44. PMID 25319996 DOI: 10.1101/Gr.164178.113  0.387
2014 Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC. Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis. Genome Research. 24: 1945-62. PMID 25319994 DOI: 10.1101/Gr.164830.113  0.411
2014 Thom CS, Traxler EA, Khandros E, Nickas JM, Zhou OY, Lazarus JE, Silva AP, Prabhu D, Yao Y, Aribeana C, Fuchs SY, Mackay JP, Holzbaur EL, Weiss MJ. Trim58 degrades Dynein and regulates terminal erythropoiesis. Developmental Cell. 30: 688-700. PMID 25241935 DOI: 10.1016/J.Devcel.2014.07.021  0.697
2014 Mills JA, Paluru P, Weiss MJ, Gadue P, French DL. Hematopoietic differentiation of pluripotent stem cells in culture. Methods in Molecular Biology (Clifton, N.J.). 1185: 181-94. PMID 25062629 DOI: 10.1007/978-1-4939-1133-2_12  0.337
2014 Strader MB, Hicks WA, Kassa T, Singleton E, Soman J, Olson JS, Weiss MJ, Mollan TL, Wilson MT, Alayash AI. Post-translational transformation of methionine to aspartate is catalyzed by heme iron and driven by peroxide: a novel subunit-specific mechanism in hemoglobin. The Journal of Biological Chemistry. 289: 22342-57. PMID 24939847 DOI: 10.1074/Jbc.M114.568980  0.336
2014 Nothnick WB, Graham A, Holbert J, Weiss MJ. miR-451 deficiency is associated with altered endometrial fibrinogen alpha chain expression and reduced endometriotic implant establishment in an experimental mouse model. Plos One. 9: e100336. PMID 24937656 DOI: 10.1371/Journal.Pone.0100336  0.336
2014 Noh JY, Weiss MJ, Poncz M. Personalized platelet transfusions: one step closer to the clinic. Cell Stem Cell. 14: 425-6. PMID 24702993 DOI: 10.1016/J.Stem.2014.03.012  0.318
2014 Crispino JD, Weiss MJ. Erythro-megakaryocytic transcription factors associated with hereditary anemia. Blood. 123: 3080-8. PMID 24652993 DOI: 10.1182/Blood-2014-01-453167  0.418
2014 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, ... ... Weiss MJ, et al. Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood. 123: 1927-37. PMID 24497530 DOI: 10.1182/Blood-2013-12-544494  0.328
2014 Cheng X, Ying L, Lu L, Galvão A, Mills J, Lin H, Kotton D, Shen S, Nostro M, Choi J, Weiss M, French D, Gadue P. Monolayer endoderm differentiation from human ESCs Stembook. PMID 23658985 DOI: 10.3824/Stembook.1.64.1  0.363
2014 Noh J, Gandre-Babbe S, Wang Y, Hayes V, Yao Y, Gadue P, Sullivan S, Chou ST, Paralkar VR, Machlus KR, Italiano JE, Kyba M, French DL, Poncz M, Weiss MJ. Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells Blood. 124: 3846-3846. DOI: 10.1182/Blood.V124.21.3846.3846  0.406
2014 Bosques L, Tang C, Krause D, Weissman SM, Gallagher PG, Weiss MJ, Tamary H, Kupfer GM. Codanin-1 Binds to Key Erythroid Genes and Its Knockdown Coupled with Ectopic Mutant Expression Recapitulates the Congenital Dyserythropoietic Anemia Type I (CDA I) Phenotype Blood. 124: 360-360. DOI: 10.1182/Blood.V124.21.360.360  0.445
2014 Ge J, Apicella M, Mills JA, Garcon L, French DL, Weiss MJ, Bessler M, Mason PJ. Dysregulation of the TGF β Pathway in Induced Pluripotent Stem Cells (iPSCs) Generated from Patients with Diamond Blackfan Anemia (DBA) Blood. 124: 254-254. DOI: 10.1182/Blood.V124.21.254.254  0.385
2014 Soman J, Strader M, Hicks W, Kassa T, Singleton E, Olson J, Weiss M, Mollan T, Wilson M, Alayash A. Crystallographic evidence for oxidative Met→Asp conversion in human hemoglobin Acta Crystallographica Section a Foundations and Advances. 70: C310-C310. DOI: 10.1107/S2053273314096892  0.311
2013 Mills JA, Wang K, Paluru P, Ying L, Lu L, Galvão AM, Xu D, Yao Y, Sullivan SK, Sullivan LM, Mac H, Omari A, Jean JC, Shen S, Gower A, ... ... Weiss MJ, et al. Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines. Blood. 122: 2047-51. PMID 23940280 DOI: 10.1182/Blood-2013-02-484444  0.346
2013 Garçon L, Ge J, Manjunath SH, Mills JA, Apicella M, Parikh S, Sullivan LM, Podsakoff GM, Gadue P, French DL, Mason PJ, Bessler M, Weiss MJ. Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients. Blood. 122: 912-21. PMID 23744582 DOI: 10.1182/Blood-2013-01-478321  0.382
2013 Traxler E, Weiss MJ. Congenital dyserythropoietic anemias: III's a charm. Blood. 121: 4614-5. PMID 23744492 DOI: 10.1182/Blood-2013-05-497602  0.309
2013 Dickson CF, Rich AM, D'Avigdor WM, Collins DA, Lowry JA, Mollan TL, Khandros E, Olson JS, Weiss MJ, Mackay JP, Lay PA, Gell DA. α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond. The Journal of Biological Chemistry. 288: 19986-20001. PMID 23696640 DOI: 10.1074/Jbc.M112.437509  0.671
2013 Paralkar VR, Weiss MJ. Long noncoding RNAs in biology and hematopoiesis. Blood. 121: 4842-6. PMID 23645840 DOI: 10.1182/Blood-2013-03-456111  0.349
2013 Gandre-Babbe S, Paluru P, Aribeana C, Chou ST, Bresolin S, Lu L, Sullivan SK, Tasian SK, Weng J, Favre H, Choi JK, French DL, Loh ML, Weiss MJ. Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia. Blood. 121: 4925-9. PMID 23620576 DOI: 10.1182/Blood-2013-01-478412  0.362
2013 Zaslavsky A, Chou ST, Schadler K, Lieberman A, Pimkin M, Kim YJ, Baek KH, Aird WC, Weiss MJ, Ryeom S. The calcineurin-NFAT pathway negatively regulates megakaryopoiesis. Blood. 121: 3205-15. PMID 23446734 DOI: 10.1182/Blood-2012-04-421172  0.407
2013 Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML. The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 121: 3228-36. PMID 23426945 DOI: 10.1182/Blood-2012-10-462689  0.703
2013 Mollan TL, Banerjee S, Wu G, Parker Siburt CJ, Tsai AL, Olson JS, Weiss MJ, Crumbliss AL, Alayash AI. α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide. The Journal of Biological Chemistry. 288: 4288-98. PMID 23264625 DOI: 10.1074/Jbc.M112.412064  0.305
2013 Weiss MJ. Role of Long Coding RNAs in Epigenetic Modulation of Hematopoiesis Blood. 122. DOI: 10.1182/Blood.V122.21.Sci-28.Sci-28  0.366
2013 Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov A, Konuthula N, An X, Narla M, Bodine DM, Hardison RC, Weiss MJ. Species-Specific Functions For Long Noncoding RNAs During Erythropoeisis Blood. 122: 2441-2441. DOI: 10.1182/Blood.V122.21.2441.2441  0.36
2013 Apicella M, Manjunath S, Mills JA, Garçon L, Podsakoff GM, French DL, Weiss MJ, Bessler M, Mason PJ. Ips Cell Lines From Members Of a Family With Variable Penetrance Of An RPS19 Mutation Recapitulate The Diamond Blackfan Anemia (DBA) Phenotype and Show Differences In Ribosome Biogenesis and TGF Beta Signaling Blood. 122: 1224-1224. DOI: 10.1182/Blood.V122.21.1224.1224  0.37
2013 Heuston EF, Lichtenberg J, Anderson SM, Paralkar VR, Capone CK, Hardison RC, Weiss MJ, Bodine DM. Differences In The Genome-Wide Epigenetic Signatures Of mRNA and Long Non-Coding RNA Genes In Mouse Erythroblasts and Megakaryocytes Blood. 122: 1198-1198. DOI: 10.1182/Blood.V122.21.1198.1198  0.34
2012 Chou ST, Byrska-Bishop M, Tober JM, Yao Y, Vandorn D, Opalinska JB, Mills JA, Choi JK, Speck NA, Gadue P, Hardison RC, Nemiroff RL, French DL, Weiss MJ. Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 17573-8. PMID 23045704 DOI: 10.1073/Pnas.1211175109  0.31
2012 Roy A, Cowan G, Mead AJ, Filippi S, Bohn G, Chaidos A, Tunstall O, Chan JK, Choolani M, Bennett P, Kumar S, Atkinson D, Wyatt-Ashmead J, Hu M, Stumpf MP, ... ... Weiss MJ, et al. Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21. Proceedings of the National Academy of Sciences of the United States of America. 109: 17579-84. PMID 23045701 DOI: 10.1073/Pnas.1211405109  0.356
2012 Raess PW, Paessler ME, Bagg A, Weiss MJ, Choi JK. α-Hemoglobin-stabilizing protein is a sensitive and specific marker of erythroid precursors. The American Journal of Surgical Pathology. 36: 1538-47. PMID 22982896 DOI: 10.1097/Pas.0B013E31825Fa501  0.342
2012 Meng R, Wang Y, Yao Y, Zhang Z, Harper DC, Heijnen HF, Sitaram A, Li W, Raposo G, Weiss MJ, Poncz M, Marks MS. SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models. Blood. 120: 404-14. PMID 22611153 DOI: 10.1182/Blood-2011-11-389551  0.316
2012 Chung EY, Psathas JN, Yu D, Li Y, Weiss MJ, Thomas-Tikhonenko A. CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis. The Journal of Clinical Investigation. 122: 2257-66. PMID 22546857 DOI: 10.1172/Jci45851  0.337
2012 Cheng X, Ying L, Lu L, Galvão AM, Mills JA, Lin HC, Kotton DN, Shen SS, Nostro MC, Choi JK, Weiss MJ, French DL, Gadue P. Self-renewing endodermal progenitor lines generated from human pluripotent stem cells. Cell Stem Cell. 10: 371-84. PMID 22482503 DOI: 10.1016/J.Stem.2012.02.024  0.36
2012 Khandros E, Thom CS, D'Souza J, Weiss MJ. Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia. Blood. 119: 5265-75. PMID 22427201 DOI: 10.1182/Blood-2011-12-397729  0.717
2012 Mollan TL, Khandros E, Weiss MJ, Olson JS. Kinetics of α-globin binding to α-hemoglobin stabilizing protein (AHSP) indicate preferential stabilization of hemichrome folding intermediate. The Journal of Biological Chemistry. 287: 11338-50. PMID 22298770 DOI: 10.1074/Jbc.M111.313247  0.681
2012 Khandros E, Mollan TL, Yu X, Wang X, Yao Y, D'Souza J, Gell DA, Olson JS, Weiss MJ. Insights into hemoglobin assembly through in vivo mutagenesis of α-hemoglobin stabilizing protein. The Journal of Biological Chemistry. 287: 11325-37. PMID 22287545 DOI: 10.1074/Jbc.M111.313205  0.73
2012 Manavathi B, Lo D, Bugide S, Dey O, Imren S, Weiss MJ, Humphries RK. Functional regulation of pre-B-cell leukemia homeobox interacting protein 1 (PBXIP1/HPIP) in erythroid differentiation. The Journal of Biological Chemistry. 287: 5600-14. PMID 22187427 DOI: 10.1074/Jbc.M111.289843  0.416
2012 Thom CS, Khandros E, Yao Y, Nickas JM, Lazarus JE, Prabhu D, Zhou OY, Holzbaur EL, Weiss MJ. Trim58 Is a Putative E3 Ubiquitin Ligase That Functions in Late Stage Erythropoiesis Blood. 120: 83-83. DOI: 10.1182/Blood.V120.21.83.83  0.719
2012 Zhao G, Yu D, Blanc L, Marks MS, Weiss MJ. MiR-144/451 Facilitates Erythroid Cellular Iron Uptake by Targeting Rab14 Blood. 120: 609-609. DOI: 10.1182/Blood.V120.21.609.609  0.327
2012 Shemer OS, Yao Y, Kupfer GM, Tamary H, Weiss MJ. Modeling Congenital Dyserythropoietic Anemia Type I Through Patient-Derived Induced Pluripotent Stem Cells Blood. 120: 3196-3196. DOI: 10.1182/Blood.V120.21.3196.3196  0.395
2012 Paralkar VR, Mishra T, Luan J, Yao Y, Konuthula N, Bodine DM, Hardison RC, Weiss MJ. Long Noncoding RNAs in Erythropoiesis and Megakaryopoiesis. Blood. 120: 2331-2331. DOI: 10.1182/Blood.V120.21.2331.2331  0.362
2012 Raess PW, Bagg A, Weiss MJ, Choi JK. Alpha-Hemoglobin-Stabilizing Protein Is a Useful and Lineage-Specific Marker of Erythroid Precursors American Journal of Clinical Pathology. 138: A286-A286. DOI: 10.1093/Ajcp/138.Suppl1.265  0.329
2011 Paralkar VR, Weiss MJ. A new 'Linc' between noncoding RNAs and blood development. Genes & Development. 25: 2555-8. PMID 22190456 DOI: 10.1101/Gad.183020.111  0.32
2011 Wu W, Cheng Y, Keller CA, Ernst J, Kumar SA, Mishra T, Morrissey C, Dorman CM, Chen KB, Drautz D, Giardine B, Shibata Y, Song L, Pimkin M, Crawford GE, ... ... Weiss MJ, et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Research. 21: 1659-71. PMID 21795386 DOI: 10.1101/Gr.125088.111  0.349
2011 Crowley MA, Mollan TL, Abdulmalik OY, Butler AD, Goodwin EF, Sarkar A, Stolle CA, Gow AJ, Olson JS, Weiss MJ. A hemoglobin variant associated with neonatal cyanosis and anemia. The New England Journal of Medicine. 364: 1837-43. PMID 21561349 DOI: 10.1056/Nejmoa1013579  0.333
2011 Amigo JD, Yu M, Troadec MB, Gwynn B, Cooney JD, Lambert AJ, Chi NC, Weiss MJ, Peters LL, Kaplan J, Cantor AB, Paw BH. Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Molecular and Cellular Biology. 31: 1344-56. PMID 21248200 DOI: 10.1128/Mcb.01010-10  0.359
2011 Chou ST, VanDorn D, Yao Y, French DL, Weiss MJ. Patient-Derived Induced Pluripotent Stem Cells Reveal Distinct Hematopoietic Defects Conferred by Trisomy 21 and Truncated GATA-1 Blood. 118: 911-911. DOI: 10.1182/Blood.V118.21.911.911  0.366
2011 Figueroa ME, Malinge S, Chlon TM, Li Y, Paietta E, Fernandez HF, Tallman MS, Weiss MJ, Chou ST, Melnick A, Crispino J. Development of Acute Megakaryoblastic Leukemia in Down Syndrome Is Associated with Sequential Epigenetic Changes That Target the Down Syndrome Critical Region on Chromosome 21, Blood. 118: 3451-3451. DOI: 10.1182/Blood.V118.21.3451.3451  0.314
2011 Ishikawa Y, Maeda M, Li M, Lee S, Feldstein JT, Kiyoi H, Naoe T, Weiss MJ, Heuser JE, Maeda T. Clathrin Assembly Protein CALM Is Necessary for Leukemia Cell Proliferation and Erythroid Development Via Regulating Transferrin Receptor Endocytosis Blood. 118: 244-244. DOI: 10.1182/Blood.V118.21.244.244  0.395
2011 Weiss M. Control of antioxidant activities by microRNAs during red blood cell development Free Radical Biology and Medicine. 51: S1-S2. DOI: 10.1016/J.Freeradbiomed.2011.10.005  0.3
2010 Khandros E, Weiss MJ. Protein quality control during erythropoiesis and hemoglobin synthesis. Hematology/Oncology Clinics of North America. 24: 1071-88. PMID 21075281 DOI: 10.1016/J.Hoc.2010.08.013  0.694
2010 Nasimuzzaman M, Khandros E, Wang X, Kong Y, Zhao H, Weiss D, Rivella S, Weiss MJ, Persons DA. Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia. American Journal of Hematology. 85: 820-2. PMID 20815047 DOI: 10.1002/Ajh.21829  0.737
2010 Yu D, dos Santos CO, Zhao G, Jiang J, Amigo JD, Khandros E, Dore LC, Yao Y, D'Souza J, Zhang Z, Ghaffari S, Choi J, Friend S, Tong W, Orange JS, ... ... Weiss MJ, et al. miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes & Development. 24: 1620-33. PMID 20679398 DOI: 10.1101/Gad.1942110  0.673
2010 Mollan TL, Yu X, Weiss MJ, Olson JS. The role of alpha-hemoglobin stabilizing protein in redox chemistry, denaturation, and hemoglobin assembly. Antioxidants & Redox Signaling. 12: 219-31. PMID 19659437 DOI: 10.1089/Ars.2009.2780  0.475
2010 Malinge S, Kirsammer G, Bliss-Moreau M, Chlon TM, Diebold L, Chou ST, Weiss M, Gurbuxani S, Crispino J. Development of a Mouse Model of DS Megakaryoblastic Leukemia and Identification of the Hsa21 Gene DYRK1A as a Prominent Contributor to DS-AMKL Blood. 116: 469-469. DOI: 10.1182/Blood.V116.21.469.469  0.396
2009 Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB. Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Molecular Cell. 36: 682-95. PMID 19941827 DOI: 10.1016/J.Molcel.2009.11.002  0.367
2009 Cheng Y, Wu W, Kumar SA, Yu D, Deng W, Tripic T, King DC, Chen KB, Zhang Y, Drautz D, Giardine B, Schuster SC, Miller W, Chiaromonte F, Zhang Y, ... ... Weiss MJ, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Research. 19: 2172-84. PMID 19887574 DOI: 10.1101/Gr.098921.109  0.377
2009 Maeda T, Ito K, Merghoub T, Poliseno L, Hobbs RM, Wang G, Dong L, Maeda M, Dore LC, Zelent A, Luzzatto L, Teruya-Feldstein J, Weiss MJ, Pandolfi PP. LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Developmental Cell. 17: 527-40. PMID 19853566 DOI: 10.1016/J.Devcel.2009.09.005  0.354
2009 Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, Leu NA, Yau PM, Donald RG, Weiss MJ, Baker DP, McLaughlin KJ, Scott P, Fuchs SY. Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Molecular and Cellular Biology. 29: 6401-12. PMID 19805514 DOI: 10.1128/Mcb.00478-09  0.31
2009 Gell DA, Feng L, Zhou S, Jeffrey PD, Bendak K, Gow A, Weiss MJ, Shi Y, Mackay JP. A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin. The Journal of Biological Chemistry. 284: 29462-9. PMID 19706593 DOI: 10.1074/Jbc.M109.027045  0.347
2009 Gadue P, Weiss MJ. Stem cells unscramble yolk sac hematopoiesis. Blood. 114: 1455-6. PMID 19696206 DOI: 10.1182/Blood-2009-06-226209  0.319
2009 Chou ST, Khandros E, Bailey LC, Nichols KE, Vakoc CR, Yao Y, Huang Z, Crispino JD, Hardison RC, Blobel GA, Weiss MJ. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 114: 983-94. PMID 19491391 DOI: 10.1182/Blood-2009-03-207944  0.721
2009 Yu X, Mollan TL, Butler A, Gow AJ, Olson JS, Weiss MJ. Analysis of human alpha globin gene mutations that impair binding to the alpha hemoglobin stabilizing protein. Blood. 113: 5961-9. PMID 19349619 DOI: 10.1182/Blood-2008-12-196030  0.504
2009 Weiss MJ. Transcriptional Regulation of Erythropoiesis. Blood. 114. DOI: 10.1182/Blood.V114.22.Sci-7.Sci-7  0.405
2008 Cheng Y, King DC, Dore LC, Zhang X, Zhou Y, Zhang Y, Dorman C, Abebe D, Kumar SA, Chiaromonte F, Miller W, Green RD, Weiss MJ, Hardison RC. Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif. Genome Research. 18: 1896-905. PMID 18818370 DOI: 10.1101/Gr.083089.108  0.345
2008 Chou ST, Opalinska JB, Yao Y, Fernandes MA, Kalota A, Brooks JS, Choi JK, Gewirtz AM, Danet-Desnoyers GA, Nemiroff RL, Weiss MJ. Trisomy 21 enhances human fetal erythro-megakaryocytic development. Blood. 112: 4503-6. PMID 18812473 DOI: 10.1182/Blood-2008-05-157859  0.377
2008 dos Santos CO, Dore LC, Valentine E, Shelat SG, Hardison RC, Ghosh M, Wang W, Eisenstein RS, Costa FF, Weiss MJ. An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. The Journal of Biological Chemistry. 283: 26956-64. PMID 18676996 DOI: 10.1074/Jbc.M802421200  0.365
2008 dos Santos CO, Zhou S, Secolin R, Wang X, Cunha AF, Higgs DR, Kwiatkowski JL, Thein SL, Gallagher PG, Costa FF, Weiss MJ. Population analysis of the alpha hemoglobin stabilizing protein (AHSP) gene identifies sequence variants that alter expression and function. American Journal of Hematology. 83: 103-8. PMID 17874450 DOI: 10.1002/Ajh.21041  0.396
2008 Amigo J, Yu M, dos Santos CO, Paradkar PN, Cooney JD, Kaplan J, Weiss MJ, Cantor AB, Paw BH. Mitoferrin1 Transgenic Zebrafish Line Serves as a Model to Study Erythroid Cell Fate during Hematopoiesis Blood. 112: 3576-3576. DOI: 10.1182/Blood.V112.11.3576.3576  0.412
2008 Santos COd, Yu D, Amigo J, Kandros E, Valentine ER, Shelat S, Dore LC, Yao Y, Souza JD, Ghaffari S, Paw BH, Orange JS, Weiss MJ. The microRNA144/451 Locus Enhances Nuclear FOXO3a Activity to Protect Erythroid Cells against Oxidant Stress Blood. 112: 277-277. DOI: 10.1182/Blood.V112.11.277.277  0.309
2008 Chou ST, Bailey C, Yao Y, Huang Z, Nichols K, Crispino J, Hardison R, Blobel G, Vakoc C, Weiss MJ. Graded Repression of PU.1 Expression by GATA Factors Influence Hematopoietic Progenitor Cell Fate Blood. 112: 2469-2469. DOI: 10.1182/Blood.V112.11.2469.2469  0.437
2007 Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. The Journal of Clinical Investigation. 117: 3890-9. PMID 18060035 DOI: 10.1172/Jci33010  0.324
2007 Yu X, Kong Y, Dore LC, Abdulmalik O, Katein AM, Zhou S, Choi JK, Gell D, Mackay JP, Gow AJ, Weiss MJ. An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis. The Journal of Clinical Investigation. 117: 1856-65. PMID 17607360 DOI: 10.1172/Jci31664  0.615
2007 Dore LC, dos Santos CO, Amigo J, Dorman C, Wu W, Hardison RC, Paw BH, Weiss MJ. A GATA-1-Regulated microRNA Cluster That Is Essential for Erythropoiesis. Blood. 110: 378-378. DOI: 10.1182/Blood.V110.11.378.378  0.35
2007 Chou ST, Bailey CL, Hardison RC, Blobel GA, Vakoc CR, Weiss MJ. GATA-1 Represses PU.1/Sfpi-1 Gene Transcription in Erythro-Megakaryocytic Progenitors. Blood. 110: 1226-1226. DOI: 10.1182/Blood.V110.11.1226.1226  0.416
2007 Weiss MJ. Multiple functions for alpha hemoglobin stabilizing protein (AHSP) in hemoglobin synthesis and homeostasis Blood Cells Molecules and Diseases. 38: 187-188. DOI: 10.1016/J.Bcmd.2006.10.152  0.321
2006 Wang H, Zhang Y, Cheng Y, Zhou Y, King DC, Taylor J, Chiaromonte F, Kasturi J, Petrykowska H, Gibb B, Dorman C, Miller W, Dore LC, Welch J, Weiss MJ, et al. Experimental validation of predicted mammalian erythroid cis-regulatory modules. Genome Research. 16: 1480-92. PMID 17038566 DOI: 10.1101/Gr.5353806  0.338
2006 Gell DA, Westman BJ, Gorman D, Liew C, Welch JJ, Weiss MJ, Mackay JP. A novel haem-binding interface in the 22 kDa haem-binding protein p22HBP. Journal of Molecular Biology. 362: 287-97. PMID 16905148 DOI: 10.1016/J.Jmb.2006.07.010  0.31
2006 Zhou S, Olson JS, Fabian M, Weiss MJ, Gow AJ. Biochemical fates of alpha hemoglobin bound to alpha hemoglobin-stabilizing protein AHSP. The Journal of Biological Chemistry. 281: 32611-8. PMID 16901899 DOI: 10.1074/Jbc.M607311200  0.312
2006 Lai MI, Jiang J, Silver N, Best S, Menzel S, Mijovic A, Colella S, Ragoussis J, Garner C, Weiss MJ, Thein SL. Alpha-haemoglobin stabilising protein is a quantitative trait gene that modifies the phenotype of beta-thalassaemia. British Journal of Haematology. 133: 675-82. PMID 16704446 DOI: 10.1111/J.1365-2141.2006.06075.X  0.36
2006 Hodge D, Coghill E, Keys J, Maguire T, Hartmann B, McDowall A, Weiss M, Grimmond S, Perkins A. A global role for EKLF in definitive and primitive erythropoiesis Blood. 107: 3359-3370. PMID 16380451 DOI: 10.1182/Blood-2005-07-2888  0.415
2006 Olsen AL, Stachura DL, Weiss MJ. Designer blood: creating hematopoietic lineages from embryonic stem cells. Blood. 107: 1265-75. PMID 16254136 DOI: 10.1182/Blood-2005-09-3621  0.699
2006 Stachura DL, Chou ST, Weiss MJ. Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. Blood. 107: 87-97. PMID 16144799 DOI: 10.1182/Blood-2005-07-2740  0.717
2006 Yu X, Kong Y, Dore LC, Katein AM, Choi JK, Gow AJ, Weiss MJ. Alpha Hemoglobin Stabilizing Protein (AHSP) Optimizes Hemoglobin A Synthesis by Maintaining a Pool of Viable Alpha Globin Subunits. Blood. 108: 650-650. DOI: 10.1182/Blood.V108.11.650.650  0.61
2006 Santos COd, Dore LC, Ollala ST, Costa FF, Weiss MJ. Regulation of Alpha Hemoglobin Stabilizing Protein (AHSP) mRNA Stability by a 3′ UTR Iron Response Element. Blood. 108: 535-535. DOI: 10.1182/Blood.V108.11.535.535  0.351
2006 Adachi K, Zhao Y, Lakka V, Weiss MJ, Surrey S. Assembly of Recently Translated Human γ-Globin Chains with a Pool of α-Globin Chains To Form Hb F in a Cell-Free System. Blood. 108: 366-366. DOI: 10.1182/Blood.V108.11.366.366  0.308
2005 Weiss MJ, Zhou S, Feng L, Gell DA, Mackay JP, Shi Y, Gow AJ. Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia. Annals of the New York Academy of Sciences. 1054: 103-17. PMID 16339656 DOI: 10.1196/Annals.1345.013  0.375
2005 Gallagher PG, Liem RI, Wong E, Weiss MJ, Bodine DM. GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene. The Journal of Biological Chemistry. 280: 39016-23. PMID 16186125 DOI: 10.1074/Jbc.M506062200  0.427
2005 Munugalavadla V, Dore LC, Tan BL, Hong L, Vishnu M, Weiss MJ, Kapur R. Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Molecular and Cellular Biology. 25: 6747-59. PMID 16024808 DOI: 10.1128/Mcb.25.15.6747-6759.2005  0.4
2005 Feng L, Zhou S, Gu L, Gell DA, Mackay JP, Weiss MJ, Gow AJ, Shi Y. Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem. Nature. 435: 697-701. PMID 15931225 DOI: 10.1038/Nature03609  0.333
2005 Vakoc CR, Letting DL, Gheldof N, Sawado T, Bender MA, Groudine M, Weiss MJ, Dekker J, Blobel GA. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Molecular Cell. 17: 453-62. PMID 15694345 DOI: 10.1016/J.Molcel.2004.12.028  0.336
2005 Zhou S, Weiss MJ, Gow AJ. The Role of Alpha Hemoglobin Stabilizing Protein (AHSP) in the Formation of Hemoglobin A. Blood. 106: 3639-3639. DOI: 10.1182/Blood.V106.11.3639.3639  0.314
2005 Lai MI, Jiang J, Silver N, Best S, Menzel S, Garner C, Weiss MJ, Thein SL. AHSP Is a Quantitative Trait Gene That Modifies the Phenotype of β Thalassemia. Blood. 106: 3638-3638. DOI: 10.1182/Blood.V106.11.3638.3638  0.36
2005 Dore LC, Vakoc CR, Blobel GA, Hardison RC, Bodine DM, Gallagher PG, Weiss MJ. Genomic Organization, Chromatin Structure, and Transcriptional Regulation of the Murine Alpha Hemoglobin Stabilizing Protein (AHSP) Gene. Blood. 106: 3633-3633. DOI: 10.1182/Blood.V106.11.3633.3633  0.434
2005 Santos COd, Zhou S, Albuquerque DM, Saad S, Weiss MJ, Costa FF. A Natural Variant Sequence in the AHSP Gene May Impact Severity of Beta-Thalassemia. Blood. 106: 3629-3629. DOI: 10.1182/Blood.V106.11.3629.3629  0.369
2005 Santos COd, Duarte A, Dore LC, Saad S, Weiss MJ, Costa FF. A Stem-Loop in the 3′-UTR Mediates Iron-Dependent Regulation of Alpha Hemoglobin Stabilizing Protein mRNA Stability. Blood. 106: 3628-3628. DOI: 10.1182/Blood.V106.11.3628.3628  0.401
2005 Pilon AM, Zhou D, Weiss MJ, Townes TM, Bodine DM, Gallagher PG. The Human Alpha Hemoglobin Stabilizing Protein (AHSP) Gene Locus in EKLF-Deficient Erythroid Cells. Blood. 106: 1740-1740. DOI: 10.1182/Blood.V106.11.1740.1740  0.396
2004 Feng L, Gell DA, Zhou S, Gu L, Kong Y, Li J, Hu M, Yan N, Lee C, Rich AM, Armstrong RS, Lay PA, Gow AJ, Weiss MJ, Mackay JP, et al. Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin. Cell. 119: 629-40. PMID 15550245 DOI: 10.1016/J.Cell.2004.11.025  0.526
2004 Kong Y, Zhou S, Kihm AJ, Katein AM, Yu X, Gell DA, Mackay JP, Adachi K, Foster-Brown L, Louden CS, Gow AJ, Weiss MJ. Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia. The Journal of Clinical Investigation. 114: 1457-66. PMID 15545996 DOI: 10.1172/Jci21982  0.618
2004 Welch JJ, Watts JA, Vakoc CR, Yao Y, Wang H, Hardison RC, Blobel GA, Chodosh LA, Weiss MJ. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood. 104: 3136-47. PMID 15297311 DOI: 10.1182/Blood-2004-04-1603  0.39
2004 Viprakasit V, Tanphaichitr VS, Chinchang W, Sangkla P, Weiss MJ, Higgs DR. Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia. Blood. 103: 3296-9. PMID 14715623 DOI: 10.1182/Blood-2003-11-3957  0.357
2004 Wang Q, Miyakoda M, Yang W, Khillan J, Stachura DL, Weiss MJ, Nishikura K. Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. The Journal of Biological Chemistry. 279: 4952-61. PMID 14613934 DOI: 10.1074/Jbc.M310162200  0.675
2004 Zhou S, Gell D, Kong Y, Li J, Mackay JP, Weiss MJ, Gow AJ. Mechanisms of Alpha Hemoglobin Stabilizing Protein (AHSP) Actions. Blood. 104: 499-499. DOI: 10.1182/Blood.V104.11.499.499  0.531
2004 Pilon AM, Wong C, Garrett-Beal LJ, Weiss M, Gallagher PG, Bodine DM. Chromatin Remodeling of the Mouse AHSP Gene Requires EKLF. Blood. 104: 375-375. DOI: 10.1182/Blood.V104.11.375.375  0.37
2003 Grass JA, Boyer ME, Pal S, Wu J, Weiss MJ, Bresnick EH. GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proceedings of the National Academy of Sciences of the United States of America. 100: 8811-6. PMID 12857954 DOI: 10.1073/Pnas.1432147100  0.382
2003 Rylski M, Welch JJ, Chen YY, Letting DL, Diehl JA, Chodosh LA, Blobel GA, Weiss MJ. GATA-1-mediated proliferation arrest during erythroid maturation. Molecular and Cellular Biology. 23: 5031-42. PMID 12832487 DOI: 10.1128/Mcb.23.14.5031-5042.2003  0.392
2003 Letting DL, Rakowski C, Weiss MJ, Blobel GA. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Molecular and Cellular Biology. 23: 1334-40. PMID 12556492 DOI: 10.1128/Mcb.23.4.1334-1340.2003  0.354
2002 Johnson KD, Grass JA, Boyer ME, Kiekhaefer CM, Blobel GA, Weiss MJ, Bresnick EH. Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 11760-5. PMID 12193659 DOI: 10.1073/Pnas.192285999  0.319
2002 Gell D, Kong Y, Eaton SA, Weiss MJ, Mackay JP. Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein. The Journal of Biological Chemistry. 277: 40602-9. PMID 12192002 DOI: 10.1074/Jbc.M206084200  0.542
2002 Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachl K, Simon MC, Blobel GA, Weiss MJ. An abundant erythroid protein that stabilizes free α-haemoglobin Nature. 417: 758-763. PMID 12066189 DOI: 10.1038/Nature00803  0.563
2000 Shirihai OS, Gregory T, Yu C, Orkin SH, Weiss MJ. ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. The Embo Journal. 19: 2492-502. PMID 10835348 DOI: 10.1093/Emboj/19.11.2492  0.375
2000 Nichols KE, Crispino JD, Poncz M, White JG, Orkin SH, Maris JM, Weiss MJ. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA 1 Nature Genetics. 24: 266-270. PMID 10700180 DOI: 10.1038/73480  0.388
1999 Orkin SH, Weiss MJ. Cutting red-cell production Nature. 401: 433-436. PMID 10519540 DOI: 10.1038/46699  0.304
1999 Hung HL, Lau J, Kim AY, Weiss MJ, Blobel GA. CREB-Binding protein acetylates hematopoietic transcription factor GATA- 1 at functionally important sites Molecular and Cellular Biology. 19: 3496-3505. PMID 10207073 DOI: 10.1128/Mcb.19.5.3496  0.403
1999 Kapur R, Cooper R, Xiao X, Weiss MJ, Donovan P, Williams DA. The Presence of Novel Amino Acids in the Cytoplasmic Domain of Stem Cell Factor Results in Hematopoietic Defects inSteel17H Mice Blood. 94: 1915-1925. DOI: 10.1182/Blood.V94.6.1915  0.378
1999 Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression Blood. 94: 87-96. DOI: 10.1182/Blood.V94.1.87.413K41_87_96  0.41
1995 Weiss MJ, Orkin SH. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis Proceedings of the National Academy of Sciences of the United States of America. 92: 9623-9627. PMID 7568185 DOI: 10.1073/Pnas.92.21.9623  0.322
1994 Weiss MJ, Keller G, Orkin SH. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1- embryonic stem cells Genes and Development. 8: 1184-1197. PMID 7926723 DOI: 10.1101/Gad.8.10.1184  0.306
1988 Weiss MJ, Cole DE, Ray K, Whyte MP, Lafferty MA, Mulivor RA, Harris H. A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia. Proceedings of the National Academy of Sciences of the United States of America. 85: 7666-9. PMID 3174660 DOI: 10.1073/Pnas.85.20.7666  0.304
1987 Poncz M, Surrey S, LaRocco P, Weiss M, Rappaport E, Conway T, Schwartz E. Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line Blood. 69: 219-223. DOI: 10.1182/Blood.V69.1.219.219  0.308
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