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Karl Ekwall - Publications

Affiliations: 
Bioscience and Nutrition Karolinska Institute, Stockholm, Sweden 
Area:
Epigenetics / histone modification patterns
Website:
http://natvet.sh.se/ekwall_lab/

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Laurent M, Cordeddu L, Zahedi Y, Ekwall K. LEO1 Is Required for Efficient Entry into Quiescence, Control of H3K9 Methylation and Gene Expression in Human Fibroblasts. Biomolecules. 13. PMID 38002344 DOI: 10.3390/biom13111662  0.429
2023 Zahedi Y, Zeng S, Ekwall K. An essential role for the Ino80 chromatin remodeling complex in regulation of gene expression during cellular quiescence. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 31: 14. PMID 37043046 DOI: 10.1007/s10577-023-09723-x  0.467
2021 Shoaib M, Chen Q, Shi X, Nair N, Prasanna C, Yang R, Walter D, Frederiksen KS, Einarsson H, Svensson JP, Liu CF, Ekwall K, Lerdrup M, Nordenskiöld L, Sørensen CS. Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes. Nature Communications. 12: 4800. PMID 34417450 DOI: 10.1038/s41467-021-25051-2  0.479
2021 Dong W, Prasad P, Lennartsson A, Ekwall K. The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling. International Journal of Molecular Sciences. 22. PMID 33670267 DOI: 10.3390/ijms22041793  0.373
2020 Zahedi Y, Durand-Dubief M, Ekwall K. High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence. International Journal of Molecular Sciences. 21. PMID 33260998 DOI: 10.3390/ijms21239022  0.745
2020 Larsson C, Cordeddu L, Siggens L, Pandzic T, Kundu S, He L, Ali MA, Pristovšek N, Hartman K, Ekwall K, Sjöblom T. Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression. Clinical Epigenetics. 12: 74. PMID 32471474 DOI: 10.1186/S13148-020-00863-Z  0.355
2020 Dong W, Oya E, Zahedi Y, Prasad P, Svensson JP, Lennartsson A, Ekwall K, Durand-Dubief M. Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin. Scientific Reports. 10: 6055. PMID 32269268 DOI: 10.1038/S41598-020-63209-Y  0.767
2020 Mujahed H, Miliara S, Neddermeyer AH, Bengtzen S, Nilsson C, Deneberg S, Cordeddu L, Ekwall K, Lennartsson A, Lehmann S. AML Displays Increased CTCF Occupancy Associated to Aberrant Gene Expression and Transcription Factor Binding. Blood. PMID 32232485 DOI: 10.1182/Blood.2019002326  0.448
2020 Birot A, Tormos-Pérez M, Vaur S, Feytout A, Jaegy J, Alonso Gil D, Vazquez S, Ekwall K, Javerzat JP. The CDK Pef1 and Protein Phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes. Elife. 9. PMID 31895039 DOI: 10.7554/Elife.50556  0.384
2019 Brusselaers N, Ekwall K, Durand-Dubief M. Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis. Human Genomics. 13: 54. PMID 31699156 DOI: 10.1186/S40246-019-0241-3  0.669
2019 Oya E, Nakagawa R, Yoshimura Y, Tanaka M, Nishibuchi G, Machida S, Shirai A, Ekwall K, Kurumizaka H, Tagami H, Nakayama JI. H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly. Embo Reports. e48111. PMID 31468675 DOI: 10.15252/Embr.201948111  0.488
2019 Pagé V, Chen JJ, Durand-Dubief M, Grabowski D, Oya E, Sanso M, Martin RD, Hébert TE, Fisher RP, Ekwall K, Tanny JC. Histone H2B Ubiquitylation Regulates Histone Gene Expression by Suppressing Antisense Transcription in Fission Yeast. Genetics. PMID 31345994 DOI: 10.1534/Genetics.119.302499  0.81
2019 Oya E, Durand-Dubief M, Cohen A, Maksimov V, Schurra C, Nakayama JI, Weisman R, Arcangioli B, Ekwall K. Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence. Epigenetics & Chromatin. 12: 45. PMID 31315658 DOI: 10.1186/S13072-019-0292-7  0.74
2019 Birot A, Tormos-Pérez M, Vaur S, Feytout A, Jaegy J, Gil DA, Vazquez S, Ekwall K, Javerzat J. Author response: The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes Elife. DOI: 10.7554/Elife.50556.Sa2  0.365
2018 Thodberg M, Thieffry A, Bornholdt J, Boyd M, Holmberg C, Azad A, Workman CT, Chen Y, Ekwall K, Nielsen O, Sandelin A. Comprehensive profiling of the fission yeast transcription start site activity during stress and media response. Nucleic Acids Research. PMID 30566651 DOI: 10.1093/Nar/Gky1227  0.42
2018 Jurisic A, Robin C, Tarlykov P, Siggens L, Schoell B, Jauch A, Ekwall K, Sørensen CS, Lipinski M, Shoaib M, Ogryzko V. Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains. Nucleic Acids Research. PMID 30215776 DOI: 10.1093/Nar/Gky818  0.43
2018 Maksimov V, Oya E, Tanaka M, Kawaguchi T, Hachisuka A, Ekwall K, Bjerling P, Nakayama JI. The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast. Plos One. 13: e0201101. PMID 30110338 DOI: 10.1371/Journal.Pone.0201101  0.466
2018 Fauquenoy S, Migeot V, Finet O, Yague-Sanz C, Khorosjutina O, Ekwall K, Hermand D. Repression of Cell Differentiation by a cis-Acting lincRNA in Fission Yeast. Current Biology : Cb. PMID 29395921 DOI: 10.1016/J.Cub.2017.12.048  0.484
2017 Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, ... ... Ekwall K, et al. FANTOM5 CAGE profiles of human and mouse samples. Scientific Data. 4: 170112. PMID 28850106 DOI: 10.1038/Sdata.2017.112  0.377
2017 Birot A, Eguienta K, Vazquez S, Claverol S, Bonneu M, Ekwall K, Javerzat JP, Vaur S. A second Wpl1 anti-cohesion pathway requires dephosphorylation of fission yeast kleisin Rad21 by PP4. The Embo Journal. PMID 28438891 DOI: 10.15252/Embj.201696050  0.422
2017 Tobiasson M, Abdulkadir H, Lennartsson A, Katayama S, Marabita F, De Paepe A, Karimi M, Krjutskov K, Einarsdottir E, Grövdal M, Jansson M, Ben Azenkoud A, Corddedu L, Lehmann S, Ekwall K, et al. Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease. Oncotarget. PMID 28427179 DOI: 10.18632/Oncotarget.15807  0.508
2017 Zaghloul EM, Gissberg O, Moreno PM, Siggens L, Hällbrink M, Jørgensen AS, Ekwall K, Zain R, Wengel J, Lundin KE, Smith CI. CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression. Nucleic Acids Research. PMID 28334749 DOI: 10.1093/Nar/Gkx111  0.425
2016 Qu Y, Siggens L, Cordeddu L, Gaidzik VI, Karlsson K, Bullinger L, Döhner K, Ekwall K, Lehmann S, Lennartsson A. Cancer specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia. Blood. PMID 28003272 DOI: 10.1182/Blood-2016-07-726877  0.505
2016 Persson J, Steglich B, Smialowska A, Boyd M, Bornholdt J, Andersson R, Schurra C, Arcangioli B, Sandelin A, Nielsen O, Ekwall K. Regulating retrotransposon activity through the use of alternative transcription start sites. Embo Reports. PMID 26902262 DOI: 10.15252/Embr.201541866  0.47
2015 Sadeghi L, Prasad P, Ekwall K, Cohen A, Svensson JP. The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast. Embo Reports. PMID 26518661 DOI: 10.15252/Embr.201541214  0.57
2015 Allshire RC, Ekwall K. Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe. Cold Spring Harbor Perspectives in Biology. 7: a018770. PMID 26134317 DOI: 10.1101/Cshperspect.A018770  0.563
2015 Steglich B, Strålfors A, Khorosjutina O, Persson J, Smialowska A, Javerzat JP, Ekwall K. The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast. Plos Genetics. 11: e1005101. PMID 25798942 DOI: 10.1371/Journal.Pgen.1005101  0.55
2015 Prasad P, Lennartsson A, Ekwall K. The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia. Biomed Research International. 2015: 347571. PMID 25789315 DOI: 10.1155/2015/347571  0.402
2015 Svensson JP, Shukla M, Menendez-Benito V, Norman-Axelsson U, Audergon P, Sinha I, Tanny JC, Allshire RC, Ekwall K. A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin. Genome Research. 25: 872-83. PMID 25778913 DOI: 10.1101/Gr.188870.114  0.701
2015 Kärblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, Kylsten P, Ekwall K, Swoboda P, Truve E, Sarmiento C. ABCE1 is a highly conserved RNA silencing suppressor. Plos One. 10: e0116702. PMID 25659154 DOI: 10.1371/Journal.Pone.0116702  0.355
2015 Siggens L, Cordeddu L, Rönnerblad M, Lennartsson A, Ekwall K. Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions. Epigenetics & Chromatin. 8: 4. PMID 25621013 DOI: 10.1186/1756-8935-8-4  0.5
2015 Castonguay E, White SA, Kagansky A, St-Cyr DJ, Castillo AG, Brugger C, White R, Bonilla C, Spitzer M, Earnshaw WC, Schalch T, Ekwall K, Tyers M, Allshire RC. Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing. Molecular and Cellular Biology. 35: 662-74. PMID 25487573 DOI: 10.1128/Mcb.01102-14  0.584
2014 Svensson JP, Ekwall K. Epigenetic activation and inactivation of centromeres. Epigenomics. 6: 451-4. PMID 25431935 DOI: 10.2217/Epi.14.33  0.475
2014 Rönnerblad M, Andersson R, Olofsson T, Douagi I, Karimi M, Lehmann S, Hoof I, de Hoon M, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, ... ... Ekwall K, et al. Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation. Blood. 123: e79-89. PMID 24671952 DOI: 10.1182/Blood-2013-02-482893  0.453
2014 Prasad P, Rönnerblad M, Arner E, Itoh M, Kawaji H, Lassmann T, Daub CO, Forrest AR, Lennartsson A, Ekwall K. High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis. Blood. 123: e46-57. PMID 24671951 DOI: 10.1182/Blood-2013-02-483537  0.481
2014 Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, ... ... Ekwall K, et al. A promoter-level mammalian expression atlas. Nature. 507: 462-70. PMID 24670764 DOI: 10.1038/Nature13182  0.449
2014 Siggens L, Ekwall K. Epigenetics, chromatin and genome organization: recent advances from the ENCODE project. Journal of Internal Medicine. 276: 201-14. PMID 24605849 DOI: 10.1111/Joim.12231  0.495
2014 Sadeghi L, Siggens L, Svensson JP, Ekwall K. Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity. Nature Structural & Molecular Biology. 21: 236-43. PMID 24531659 DOI: 10.1038/Nsmb.2776  0.572
2014 Smialowska A, Djupedal I, Wang J, Kylsten P, Swoboda P, Ekwall K. RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe. Biochemical and Biophysical Research Communications. 444: 254-9. PMID 24462781 DOI: 10.1016/J.Bbrc.2014.01.057  0.456
2014 Grövdal M, Karimi M, Tobiasson M, Reinius L, Jansson M, Ekwall K, Ungerstedt J, Kere J, Greco D, Hellström-Lindberg E. Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation. Leukemia. 28: 411-3. PMID 24025691 DOI: 10.1038/Leu.2013.265  0.36
2014 Tobiasson M, Karimi M, Dimitriou M, Qu Y, Lennartsson A, Abdulkadir Ali H, Unnikrishnan A, Jadersten M, Jansson M, Ben Azenkoud A, Pimanda JE, Ekwall K, Ungerstedt J, Lehmann S, Hellstrom-Lindberg E. Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients Blood. 124: 4613-4613. DOI: 10.1182/Blood.V124.21.4613.4613  0.367
2013 Prasad P, Ekwall K. A snapshot of Snf2 enzymes in fission yeast. Biochemical Society Transactions. 41: 1640-7. PMID 24256268 DOI: 10.1042/Bst20130145  0.421
2013 Steglich B, Sazer S, Ekwall K. Transcriptional regulation at the yeast nuclear envelope. Nucleus (Austin, Tex.). 4: 379-89. PMID 24021962 DOI: 10.4161/Nucl.26394  0.53
2013 Castillo AG, Pidoux AL, Catania S, Durand-Dubief M, Choi ES, Hamilton G, Ekwall K, Allshire RC. Telomeric repeats facilitate CENP-A(Cnp1) incorporation via telomere binding proteins. Plos One. 8: e69673. PMID 23936074 DOI: 10.1371/Journal.Pone.0069673  0.746
2013 Norman-Axelsson U, Durand-Dubief M, Prasad P, Ekwall K. DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast. Plos Genetics. 9: e1003371. PMID 23516381 DOI: 10.1371/Journal.Pgen.1003371  0.768
2013 Castillo AG, Pidoux AL, Catania S, Durand-Dubief M, Choi ES, Hamilton G, Ekwall K, Allshire RC. Correction: Telomeric Repeats Facilitate CENP-ACnp1Incorporation via Telomere Binding Proteins Plos One. 8. DOI: 10.1371/Annotation/C6430C38-0D7A-4B9F-Aca9-7D8B212F9F09  0.657
2012 Pointner J, Persson J, Prasad P, Norman-Axelsson U, StrÃ¥lfors A, Khorosjutina O, Krietenstein N, Svensson JP, Ekwall K, Korber P. CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe. The Embo Journal. 31: 4388-403. PMID 23103765 DOI: 10.1038/Emboj.2012.289  0.528
2012 Choi ES, Strålfors A, Catania S, Castillo AG, Svensson JP, Pidoux AL, Ekwall K, Allshire RC. Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast. Plos Genetics. 8: e1002985. PMID 23028377 DOI: 10.1371/Journal.Pgen.1002985  0.565
2012 Carlsten JO, Szilagyi Z, Liu B, Lopez MD, Szászi E, Djupedal I, Nyström T, Ekwall K, Gustafsson CM, Zhu X. Mediator promotes CENP-a incorporation at fission yeast centromeres. Molecular and Cellular Biology. 32: 4035-43. PMID 22851695 DOI: 10.1128/Mcb.00374-12  0.484
2012 Steglich B, Filion GJ, van Steensel B, Ekwall K. The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe. Nucleus (Austin, Tex.). 3: 77-87. PMID 22156748 DOI: 10.4161/Nucl.18825  0.572
2012 Michelle R, Tor O, Douagi I, Lehmann S, Ekwall K, Arner E, Lennartsson A. Analysis of DNA Methylation and Transcription During Granulopoiesis Reveals Timed Methylation Changes in Low CpG Areas That Correlate with Changed Transcriptional Activity. Blood. 120: 2334-2334. DOI: 10.1182/Blood.V120.21.2334.2334  0.445
2011 Deneberg S, Guardiola P, Lennartsson A, Qu Y, Gaidzik V, Blanchet O, Karimi M, Bengtzén S, Nahi H, Uggla B, Tidefelt U, Höglund M, Paul C, Ekwall K, Döhner K, et al. Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks. Blood. 118: 5573-82. PMID 21960591 DOI: 10.1182/Blood-2011-01-332353  0.445
2011 Sadeghi L, Bonilla C, Strålfors A, Ekwall K, Svensson JP. Podbat: a novel genomic tool reveals Swr1-independent H2A.Z incorporation at gene coding sequences through epigenetic meta-analysis. Plos Computational Biology. 7: e1002163. PMID 21901086 DOI: 10.1371/Journal.Pcbi.1002163  0.504
2011 Prasad P, Ekwall K. New insights into how chromatin remodellers direct CENP-A to centromeres. The Embo Journal. 30: 1875-6. PMID 21593726 DOI: 10.1038/Emboj.2011.131  0.485
2011 Choi ES, Strålfors A, Castillo AG, Durand-Dubief M, Ekwall K, Allshire RC. Identification of noncoding transcripts from within CENP-A chromatin at fission yeast centromeres. The Journal of Biological Chemistry. 286: 23600-7. PMID 21531710 DOI: 10.1074/Jbc.M111.228510  0.793
2011 Rhind N, Chen Z, Yassour M, Thompson DA, Haas BJ, Habib N, Wapinski I, Roy S, Lin MF, Heiman DI, Young SK, Furuya K, Guo Y, Pidoux A, Chen HM, ... ... Ekwall K, et al. Comparative functional genomics of the fission yeasts. Science (New York, N.Y.). 332: 930-6. PMID 21511999 DOI: 10.1126/Science.1203357  0.47
2011 Durand-Dubief M, Svensson JP, Persson J, Ekwall K. Topoisomerases, chromatin and transcription termination. Transcription. 2: 66-70. PMID 21468231 DOI: 10.4161/trns.2.2.14411  0.766
2011 Strålfors A, Walfridsson J, Bhuiyan H, Ekwall K. The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation. Plos Genetics. 7: e1001334. PMID 21437270 DOI: 10.1371/Journal.Pgen.1001334  0.501
2011 Chang DY, Shi G, Durand-Dubief M, Ekwall K, Lu AL. The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe. Journal of Molecular Biology. 405: 653-65. PMID 21110984 DOI: 10.1016/J.Jmb.2010.11.037  0.779
2011 Strålfors A, Ekwall K. Heterochromatin and Euchromatin—Organization, Boundaries, and Gene Regulation Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200400018.Pub2  0.576
2010 Sinha I, Buchanan L, Rönnerblad M, Bonilla C, Durand-Dubief M, Shevchenko A, Grunstein M, Stewart AF, Ekwall K. Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast. Epigenomics. 2: 377-93. PMID 22121899 DOI: 10.2217/Epi.10.18  0.812
2010 Khorosjutina O, Wanrooij PH, Walfridsson J, Szilagyi Z, Zhu X, Baraznenok V, Ekwall K, Gustafsson CM. A chromatin-remodeling protein is a component of fission yeast mediator. The Journal of Biological Chemistry. 285: 29729-37. PMID 20622008 DOI: 10.1074/Jbc.M110.153858  0.535
2010 Durand-Dubief M, Persson J, Norman U, Hartsuiker E, Ekwall K. Topoisomerase I regulates open chromatin and controls gene expression in vivo. The Embo Journal. 29: 2126-34. PMID 20526281 DOI: 10.1038/Emboj.2010.109  0.8
2010 Persson J, Ekwall K. Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation. Experimental Cell Research. 316: 1316-23. PMID 20211173 DOI: 10.1016/J.Yexcr.2010.02.029  0.597
2010 Lantermann AB, Straub T, Strålfors A, Yuan GC, Ekwall K, Korber P. Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae. Nature Structural & Molecular Biology. 17: 251-7. PMID 20118936 DOI: 10.1038/Nsmb.1741  0.523
2010 Hogan CJ, Aligianni S, Durand-Dubief M, Persson J, Will WR, Webster J, Wheeler L, Mathews CK, Elderkin S, Oxley D, Ekwall K, Varga-Weisz PD. Fission yeast Iec1-ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism. Molecular and Cellular Biology. 30: 657-74. PMID 19933844 DOI: 10.1128/Mcb.01117-09  0.775
2010 Deneberg S, Lennartsson A, Uggla B, Gaidzik V, Corbacioglu A, Nahi H, Dohner K, Ekwall K, Tidefelt U, Hoglund M, Lehmann S. Global and HOX Gene DNA Methylation In Normal Karyotype Acute Myeloid Leukemia: Clinical Implications and Molecular Correlations Blood. 116: 231-231. DOI: 10.1182/Blood.V116.21.231.231  0.419
2009 Djupedal I, Kos-Braun IC, Mosher RA, Söderholm N, Simmer F, Hardcastle TJ, Fender A, Heidrich N, Kagansky A, Bayne E, Wagner EG, Baulcombe DC, Allshire RC, Ekwall K. Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA. The Embo Journal. 28: 3832-44. PMID 19942857 DOI: 10.1038/Emboj.2009.351  0.339
2009 Buchanan L, Durand-Dubief M, Roguev A, Sakalar C, Wilhelm B, Strålfors A, Shevchenko A, Aasland R, Shevchenko A, Ekwall K, Francis Stewart A. The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. Plos Genetics. 5: e1000726. PMID 19911051 DOI: 10.1371/Journal.Pgen.1000726  0.78
2009 Johnsson A, Durand-Dubief M, Xue-Franzén Y, Rönnerblad M, Ekwall K, Wright A. HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress. Embo Reports. 10: 1009-14. PMID 19633696 DOI: 10.1038/Embor.2009.127  0.79
2009 Durand-Dubief M, Ekwall K. Chromatin immunoprecipitation using microarrays. Methods in Molecular Biology (Clifton, N.J.). 529: 279-95. PMID 19381973 DOI: 10.1007/978-1-59745-538-1_18  0.724
2009 Lantermann A, Strålfors A, Fagerström-Billai F, Korber P, Ekwall K. Genome-wide mapping of nucleosome positions in Schizosaccharomyces pombe. Methods (San Diego, Calif.). 48: 218-25. PMID 19233281 DOI: 10.1016/J.Ymeth.2009.02.004  0.487
2009 Djupedal I, Ekwall K. Epigenetics: heterochromatin meets RNAi. Cell Research. 19: 282-95. PMID 19188930 DOI: 10.1038/Cr.2009.13  0.513
2009 Lennartsson A, Ekwall K. Histone modification patterns and epigenetic codes. Biochimica Et Biophysica Acta. 1790: 863-8. PMID 19168116 DOI: 10.1016/J.Bbagen.2008.12.006  0.53
2008 Bayne EH, Portoso M, Kagansky A, Kos-Braun IC, Urano T, Ekwall K, Alves F, Rappsilber J, Allshire RC. Splicing factors facilitate RNAi-directed silencing in fission yeast. Science (New York, N.Y.). 322: 602-6. PMID 18948543 DOI: 10.1126/Science.1164029  0.448
2008 Durand-Dubief M, Ekwall K. Heterochromatin tells CENP-A where to go. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 30: 526-9. PMID 18478529 DOI: 10.1002/Bies.20763  0.769
2008 Djupedal I, Ekwall K. Molecular biology. The paradox of silent heterochromatin. Science (New York, N.Y.). 320: 624-5. PMID 18451292 DOI: 10.1126/Science.1158923  0.403
2008 Bernard P, Schmidt CK, Vaur S, Dheur S, Drogat J, Genier S, Ekwall K, Uhlmann F, Javerzat JP. Cell-cycle regulation of cohesin stability along fission yeast chromosomes. The Embo Journal. 27: 111-21. PMID 18079700 DOI: 10.1038/Sj.Emboj.7601955  0.395
2007 Dunleavy EM, Pidoux AL, Monet M, Bonilla C, Richardson W, Hamilton GL, Ekwall K, McLaughlin PJ, Allshire RC. A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres. Molecular Cell. 28: 1029-44. PMID 18158900 DOI: 10.1016/J.Molcel.2007.10.010  0.482
2007 Ekwall K. Epigenetic control of centromere behavior. Annual Review of Genetics. 41: 63-81. PMID 17711387 DOI: 10.1146/Annurev.Genet.41.110306.130127  0.564
2007 Lejeune E, Bortfeld M, White SA, Pidoux AL, Ekwall K, Allshire RC, Ladurner AG. The chromatin-remodeling factor FACT contributes to centromeric heterochromatin independently of RNAi. Current Biology : Cb. 17: 1219-24. PMID 17614284 DOI: 10.1016/J.Cub.2007.06.028  0.543
2007 Walfridsson J, Khorosjutina O, Matikainen P, Gustafsson CM, Ekwall K. A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly. The Embo Journal. 26: 2868-79. PMID 17510629 DOI: 10.1038/Sj.Emboj.7601728  0.551
2007 Isaac S, Walfridsson J, Zohar T, Lazar D, Kahan T, Ekwall K, Cohen A. Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe. Genetics. 175: 1549-60. PMID 17449867 DOI: 10.1534/Genetics.106.068684  0.503
2007 Durand-Dubief M, Sinha I, Fagerström-Billai F, Bonilla C, Wright A, Grunstein M, Ekwall K. Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing. The Embo Journal. 26: 2477-88. PMID 17446861 DOI: 10.1038/Sj.Emboj.7601690  0.797
2007 Opel M, Lando D, Bonilla C, Trewick SC, Boukaba A, Walfridsson J, Cauwood J, Werler PJ, Carr AM, Kouzarides T, Murzina NV, Allshire RC, Ekwall K, Laue ED. Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1. Plos One. 2: e386. PMID 17440621 DOI: 10.1371/Journal.Pone.0000386  0.606
2007 Ekwall K. 'Arc' escorts siRNAs in heterochromatin assembly. Nature Structural & Molecular Biology. 14: 178-9. PMID 17334405 DOI: 10.1038/Nsmb0307-178  0.319
2007 Fagerström-Billai F, Durand-Dubief M, Ekwall K, Wright AP. Individual subunits of the Ssn6-Tup11/12 corepressor are selectively required for repression of different target genes. Molecular and Cellular Biology. 27: 1069-82. PMID 17101775 DOI: 10.1128/Mcb.01674-06  0.778
2006 Zhu X, Wirén M, Sinha I, Rasmussen NN, Linder T, Holmberg S, Ekwall K, Gustafsson CM. Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions. Molecular Cell. 22: 169-78. PMID 16630887 DOI: 10.1016/J.Molcel.2006.03.032  0.646
2006 Sinha I, Wirén M, Ekwall K. Genome-wide patterns of histone modifications in fission yeast. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 14: 95-105. PMID 16506099 DOI: 10.1007/S10577-005-1023-4  0.681
2005 Schramke V, Sheedy DM, Denli AM, Bonila C, Ekwall K, Hannon GJ, Allshire RC. Retraction: RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription. Nature. 437: 1057. PMID 16222304 DOI: 10.1038/Nature04181  0.404
2005 Djupedal I, Portoso M, Spåhr H, Bonilla C, Gustafsson CM, Allshire RC, Ekwall K. RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. Genes & Development. 19: 2301-6. PMID 16204182 DOI: 10.1101/Gad.344205  0.398
2005 Ekwall K. Genome-wide analysis of HDAC function. Trends in Genetics : Tig. 21: 608-15. PMID 16153738 DOI: 10.1016/J.Tig.2005.08.009  0.448
2005 Wirén M, Silverstein RA, Sinha I, Walfridsson J, Lee HM, Laurenson P, Pillus L, Robyr D, Grunstein M, Ekwall K. Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast. The Embo Journal. 24: 2906-18. PMID 16079916 DOI: 10.1038/Sj.Emboj.7600758  0.696
2005 Schramke V, Sheedy DM, Denli AM, Bonila C, Ekwall K, Hannon GJ, Allshire RC. RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription. Nature. 435: 1275-9. PMID 15965464 DOI: 10.1038/Nature03652  0.442
2005 Walfridsson J, Bjerling P, Thalen M, Yoo EJ, Park SD, Ekwall K. The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres. Nucleic Acids Research. 33: 2868-79. PMID 15908586 DOI: 10.1093/Nar/Gki579  0.533
2005 Silverstein RA, Ekwall K. Sin3: a flexible regulator of global gene expression and genome stability. Current Genetics. 47: 1-17. PMID 15565322 DOI: 10.1007/S00294-004-0541-5  0.591
2004 Bjerling P, Ekwall K, Egel R, Thon G. A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe. Nucleic Acids Research. 32: 4421-8. PMID 15317867 DOI: 10.1093/Nar/Gkh780  0.545
2004 Ekwall K. The roles of histone modifications and small RNA in centromere function. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 12: 535-42. PMID 15289661 DOI: 10.1023/B:Chro.0000036584.40567.E5  0.511
2004 Ekwall K. The RITS complex-A direct link between small RNA and heterochromatin. Molecular Cell. 13: 304-5. PMID 14967138 DOI: 10.1016/S1097-2765(04)00057-7  0.352
2004 Xue Y, Haas SA, Brino L, Gusnanto A, Reimers M, Talibi D, Vingron M, Ekwall K, Wright AP. A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift. Yeast (Chichester, England). 21: 25-39. PMID 14745780 DOI: 10.1002/Yea.1053  0.452
2004 Carmichael JB, Provost P, Ekwall K, Hobman TC. ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe. Molecular Biology of the Cell. 15: 1425-35. PMID 14699070 DOI: 10.1091/Mbc.E03-06-0433  0.435
2003 Appelgren H, Kniola B, Ekwall K. Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells. Journal of Cell Science. 116: 4035-42. PMID 12928332 DOI: 10.1242/Jcs.00707  0.426
2003 Nakayama J, Xiao G, Noma K, Malikzay A, Bjerling P, Ekwall K, Kobayashi R, Grewal SI. Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity. The Embo Journal. 22: 2776-87. PMID 12773392 DOI: 10.1093/Emboj/Cdg248  0.55
2003 Silverstein RA, Ekwall K. Similar mechanisms drive centromeric silencing and gene repression. Cell Cycle (Georgetown, Tex.). 2: 73-5. PMID 12695648 DOI: 10.4161/Cc.2.2.331  0.434
2003 Silverstein RA, Richardson W, Levin H, Allshire R, Ekwall K. A new role for the transcriptional corepressor SIN3; regulation of centromeres. Current Biology : Cb. 13: 68-72. PMID 12526748 DOI: 10.1016/S0960-9822(02)01401-X  0.541
2002 Provost P, Silverstein RA, Dishart D, Walfridsson J, Djupedal I, Kniola B, Wright A, Samuelsson B, Radmark O, Ekwall K. Dicer is required for chromosome segregation and gene silencing in fission yeast cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 16648-53. PMID 12482946 DOI: 10.1073/Pnas.212633199  0.421
2002 Jae Yoo E, Kyu Jang Y, Ae Lee M, Bjerling P, Bum Kim J, Ekwall K, Hyun Seong R, Dai Park S. Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast. Biochemical and Biophysical Research Communications. 295: 970-4. PMID 12127990 DOI: 10.1016/S0006-291X(02)00797-0  0.569
2002 Façanha AL, Appelgren H, Tabish M, Okorokov L, Ekwall K. The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics. The Journal of Cell Biology. 157: 1029-39. PMID 12058018 DOI: 10.1083/Jcb.200111012  0.314
2002 Bjerling P, Ekwall K. Centromere domain organization and histone modifications. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 35: 499-507. PMID 12011934 DOI: 10.1590/S0100-879X2002000500001  0.46
2002 Bjerling P, Silverstein RA, Thon G, Caudy A, Grewal S, Ekwall K. Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity. Molecular and Cellular Biology. 22: 2170-81. PMID 11884604 DOI: 10.1128/Mcb.22.7.2170-2181.2002  0.549
2001 Kniola B, O'Toole E, McIntosh JR, Mellone B, Allshire R, Mengarelli S, Hultenby K, Ekwall K. The domain structure of centromeres is conserved from fission yeast to humans. Molecular Biology of the Cell. 12: 2767-75. PMID 11553715 DOI: 10.1091/Mbc.12.9.2767  0.375
2000 Yoo EJ, Jin YH, Jang YK, Bjerling P, Tabish M, Hong SH, Ekwall K, Park SD. Fission yeast hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation. Nucleic Acids Research. 28: 2004-11. PMID 10756203 DOI: 10.1093/Nar/28.9.2004  0.465
1999 Ekwall K, Cranston G, Allshire RC. Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation. Genetics. 153: 1153-69. PMID 10545449  0.317
1999 Olsson TG, Silverstein RA, Ekwall K, Sunnerhagen P. Transient inhibition of histone deacetylase activity overcomes silencing in the mating-type region in fission yeast. Current Genetics. 35: 82-7. PMID 10079326 DOI: 10.1007/S002940050436  0.474
1999 Dang VD, Benedik MJ, Ekwall K, Choi J, Allshire RC, Levin HL. A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast. Molecular and Cellular Biology. 19: 2351-65. PMID 10022921 DOI: 10.1128/Mcb.19.3.2351  0.502
1998 Olsson TG, Ekwall K, Allshire RC, Sunnerhagen P, Partridge JF, Richardson WA. Genetic characterisation of hda1+, a putative fission yeast histone deacetylase gene. Nucleic Acids Research. 26: 3247-54. PMID 9628926 DOI: 10.1093/Nar/26.13.3247  0.567
1997 Ekwall K, Olsson T, Turner BM, Cranston G, Allshire RC. Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell. 91: 1021-32. PMID 9428524 DOI: 10.1016/S0092-8674(00)80492-4  0.537
1996 Ekwall K, Nimmo ER, Javerzat JP, Borgstrøm B, Egel R, Cranston G, Allshire R. Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. Journal of Cell Science. 109: 2637-48. PMID 8937982  0.376
1995 Allshire RC, Nimmo ER, Ekwall K, Javerzat JP, Cranston G. Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes & Development. 9: 218-33. PMID 7851795 DOI: 10.1101/Gad.9.2.218  0.413
1995 Ekwall K, Javerzat JP, Lorentz A, Schmidt H, Cranston G, Allshire R. The chromodomain protein Swi6: a key component at fission yeast centromeres. Science (New York, N.Y.). 269: 1429-31. PMID 7660126 DOI: 10.1126/Science.7660126  0.4
1994 Lind M, Lunderius C, Ekwall K, Olsson T. Physical mapping of the Schizosaccharomyces pombe histone genes. Current Genetics. 26: 553-6. PMID 7874752 DOI: 10.1007/Bf00309949  0.418
1993 Olsson T, Ekwall K, Ruusala T. The silent P mating type locus in fission yeast contains two autonomously replicating sequences. Nucleic Acids Research. 21: 855-61. PMID 8451187 DOI: 10.1093/Nar/21.4.855  0.403
1992 Ekwall K, Kermorgant M, Dujardin G, Groudinsky O, Slonimski PP. The NAM8 gene in Saccharomyces cerevisiae encodes a protein with putative RNA binding motifs and acts as a suppressor of mitochondrial splicing deficiencies when overexpressed. Molecular & General Genetics : Mgg. 233: 136-44. PMID 1603056 DOI: 10.1007/Bf00587571  0.381
1992 Ekwall K, Olsson T, Ruusala T. Trans-acting factors and properly positioned DNA elements repress mating-type genes in fission yeast. Current Genetics. 21: 331-8. PMID 1525861 DOI: 10.1007/Bf00351691  0.407
1991 Ekwall K, Ruusala T. Budding yeast CAN1 gene as a selection marker in fission yeast. Nucleic Acids Research. 19: 1150. PMID 2020549 DOI: 10.1093/Nar/19.5.1150  0.379
1991 Ekwall K, Nielsen O, Ruusala T. Repression of a mating type cassette in the fission yeast by four DNA elements. Yeast (Chichester, England). 7: 745-55. PMID 1776364 DOI: 10.1002/Yea.320070709  0.356
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