Adam Charles Puche - Publications

Anatomy and Neurobiology University of Maryland, College Park, College Park, MD 

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Liu S, Shao Z, Puche A, Wachowiak M, Rothermel M, Shipley MT. Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5680-92. PMID 25855181 DOI: 10.1523/JNEUROSCI.4953-14.2015  0.88
2015 Hsieh YC, Puche AC. GABA modulation of SVZ-derived progenitor ventral cell migration. Developmental Neurobiology. 75: 791-804. PMID 25421254 DOI: 10.1002/dneu.22249  0.88
2015 Mackenzie CF, Garofalo E, Shackelford S, Shalin V, Pugh K, Chen H, Puche A, Pasley J, Sarani B, Henry S, Bowyer M. Using an Individual Procedure Score Before and After the Advanced Surgical Skills Exposure for Trauma Course Training to Benchmark a Hemorrhage-Control Performance Metric Journal of Surgical Education. DOI: 10.1016/j.jsurg.2015.06.009  0.88
2014 Rothermel M, Carey RM, Puche A, Shipley MT, Wachowiak M. Cholinergic inputs from Basal forebrain add an excitatory bias to odor coding in the olfactory bulb. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4654-64. PMID 24672011 DOI: 10.1523/JNEUROSCI.5026-13.2014  0.88
2014 Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Sun W, Luzina IG, Webb TJ, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, et al. Human airway epithelia express catalytically active NEU3 sialidase. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L876-86. PMID 24658138 DOI: 10.1152/ajplung.00322.2013  0.88
2014 Ennis M, Puche AC, Holy T, Shipley MT. The Olfactory System The Rat Nervous System: Fourth Edition. 761-803. DOI: 10.1016/B978-0-12-374245-2.00027-9  0.88
2013 Shen WB, Plachez C, Chan A, Yarnell D, Puche AC, Fishman PS, Yarowsky P. Human neural progenitor cells retain viability, phenotype, proliferation, and lineage differentiation when labeled with a novel iron oxide nanoparticle, Molday ION Rhodamine B. International Journal of Nanomedicine. 8: 4593-600. PMID 24348036 DOI: 10.2147/IJN.S53012  0.88
2013 Shao Z, Puche AC, Shipley MT. Intraglomerular inhibition maintains mitral cell response contrast across input frequencies. Journal of Neurophysiology. 110: 2185-91. PMID 23926045 DOI: 10.1152/jn.00023.2013  0.88
2013 Liu S, Plachez C, Shao Z, Puche A, Shipley MT. Olfactory bulb short axon cell release of GABA and dopamine produces a temporally biphasic inhibition-excitation response in external tufted cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2916-26. PMID 23407950 DOI: 10.1523/JNEUROSCI.3607-12.2013  0.88
2013 Hsieh YC, Puche AC. Development of the Islands of Calleja. Brain Research. 1490: 52-60. PMID 23122882 DOI: 10.1016/j.brainres.2012.10.051  0.88
2012 Nicholson JD, Puche AC, Guo Y, Weinreich D, Slater BJ, Bernstein SL. PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. Plos One. 7: e50021. PMID 23284631 DOI: 10.1371/journal.pone.0050021  0.88
2012 Plachez C, Cato K, McLeay RC, Heng YH, Bailey TL, Gronostajski RM, Gronostasjki RM, Richards LJ, Puche AC, Piper M. Expression of nuclear factor one A and -B in the olfactory bulb. The Journal of Comparative Neurology. 520: 3135-49. PMID 22886731 DOI: 10.1002/cne.23081  0.88
2012 Esber GR, Roesch MR, Bali S, Trageser J, Bissonette GB, Puche AC, Holland PC, Schoenbaum G. Attention-related Pearce-Kaye-Hall signals in basolateral amygdala require the midbrain dopaminergic system. Biological Psychiatry. 72: 1012-9. PMID 22763185 DOI: 10.1016/j.biopsych.2012.05.023  0.88
2012 Shao Z, Puche AC, Liu S, Shipley MT. Intraglomerular inhibition shapes the strength and temporal structure of glomerular output. Journal of Neurophysiology. 108: 782-93. PMID 22592311 DOI: 10.1152/jn.00119.2012  0.88
2012 De Marchis S, Puche AC. Cellular imaging and emerging technologies for adult neurogenesis research. Frontiers in Neuroscience. 6: 41. PMID 22493567 DOI: 10.3389/fnins.2012.00041  0.88
2012 Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE. TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. The Journal of Biological Chemistry. 287: 16132-45. PMID 22447928 DOI: 10.1074/jbc.M111.310102  0.88
2012 Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, et al. NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not. The Journal of Biological Chemistry. 287: 15966-80. PMID 22403397 DOI: 10.1074/jbc.M112.346817  0.88
2012 Plachez C, Puche AC. Early specification of GAD67 subventricular derived olfactory interneurons. Journal of Molecular Histology. 43: 215-21. PMID 22389027 DOI: 10.1007/s10735-012-9394-2  0.88
2012 Tulapurkar ME, Almutairy EA, Shah NG, He JR, Puche AC, Shapiro P, Singh IS, Hasday JD. Febrile-range hyperthermia modifies endothelial and neutrophilic functions to promote extravasation. American Journal of Respiratory Cell and Molecular Biology. 46: 807-14. PMID 22281986 DOI: 10.1165/rcmb.2011-0378OC  0.88
2012 Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE. NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling. The Journal of Biological Chemistry. 287: 8214-31. PMID 22247545 DOI: 10.1074/jbc.M111.292888  0.88
2012 Liu S, Aungst JL, Puche AC, Shipley MT. Serotonin modulates the population activity profile of olfactory bulb external tufted cells. Journal of Neurophysiology. 107: 473-83. PMID 22013233 DOI: 10.1152/jn.00741.2011  0.88
2011 Yang AR, Liu J, Yi HS, Warnock KT, Wang M, June HL, Puche AC, Elnabawi A, Sieghart W, Aurelian L, June HL. Binge Drinking: In Search of its Molecular Target via the GABA(A) Receptor. Frontiers in Neuroscience. 5: 123. PMID 22022305 DOI: 10.3389/fnins.2011.00123  0.88
2011 Bovetti S, Gribaudo S, Puche AC, De Marchis S, Fasolo A. From progenitors to integrated neurons: role of neurotransmitters in adult olfactory neurogenesis. Journal of Chemical Neuroanatomy. 42: 304-16. PMID 21641990 DOI: 10.1016/j.jchemneu.2011.05.006  0.88
2011 Puche AC, Bovetti S. Studies of adult neural stem cell migration. Methods in Molecular Biology (Clifton, N.J.). 750: 227-40. PMID 21618095 DOI: 10.1007/978-1-61779-145-1_16  0.88
2011 Liu J, Yang AR, Kelly T, Puche A, Esoga C, June HL, Elnabawi A, Merchenthaler I, Sieghart W, June HL, Aurelian L. Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala. Proceedings of the National Academy of Sciences of the United States of America. 108: 4465-70. PMID 21368176 DOI: 10.1073/pnas.1019020108  0.88
2011 Parrish-Aungst S, Kiyokage E, Szabo G, Yanagawa Y, Shipley MT, Puche AC. Sensory experience selectively regulates transmitter synthesis enzymes in interglomerular circuits. Brain Research. 1382: 70-6. PMID 21276774 DOI: 10.1016/j.brainres.2011.01.068  0.88
2011 Goldblum SE, Rai U, Tripathi A, Thakar M, De Leo L, Di Toro N, Not T, Ramachandran R, Puche AC, Hollenberg MD, Fasano A. The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 144-58. PMID 20852064 DOI: 10.1096/fj.10-158972  0.88
2010 Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, Vogel SN. Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent. Mucosal Immunology. 3: 291-300. PMID 20404812 DOI: 10.1038/mi.2010.6  0.88
2010 Sultana S, Li H, Puche A, Jones O, Bryant JL, Royal W. Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine. Journal of Neurovirology. 16: 33-40. PMID 20113193 DOI: 10.3109/13550280903555712  0.88
2010 Kiyokage E, Pan YZ, Shao Z, Kobayashi K, Szabo G, Yanagawa Y, Obata K, Okano H, Toida K, Puche AC, Shipley MT. Molecular identity of periglomerular and short axon cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1185-96. PMID 20089927 DOI: 10.1523/JNEUROSCI.3497-09.2010  0.88
2010 Zufall F, Leinders-Zufall T, Puche AC. Accessory Olfactory System The Senses: a Comprehensive Reference. 4: 783-814. DOI: 10.1016/B978-012370880-9.00128-6  0.88
2010 Shipley MT, Puche AC. Olfactory Glomeruli: Structure and Circuitry Encyclopedia of Neuroscience. 119-127. DOI: 10.1016/B978-008045046-9.01813-1  0.88
2009 Shao Z, Puche AC, Kiyokage E, Szabo G, Shipley MT. Two GABAergic intraglomerular circuits differentially regulate tonic and phasic presynaptic inhibition of olfactory nerve terminals. Journal of Neurophysiology. 101: 1988-2001. PMID 19225171 DOI: 10.1152/jn.91116.2008  0.88
2009 Bovolin P, Bovetti S, Fasolo A, Katarova Z, Szabo G, Shipley MT, Margolis FL, Puche AC. Developmental regulation of metabotropic glutamate receptor 1 splice variants in olfactory bulb mitral cells. Journal of Neuroscience Research. 87: 369-79. PMID 18816797 DOI: 10.1002/jnr.21864  0.88
2008 Rifat S, Kang TJ, Mann D, Zhang L, Puche AC, Stamatos NM, Goldblum SE, Brossmer R, Cross AS. Expression of sialyltransferase activity on intact human neutrophils. Journal of Leukocyte Biology. 84: 1075-81. PMID 18664529 DOI: 10.1189/jlb.0706462  0.88
2008 Liu Q, Puche AC, Wang JB. Distribution and expression of protein kinase C interactive protein (PKCI/HINT1) in mouse central nervous system (CNS). Neurochemical Research. 33: 1263-76. PMID 18270824 DOI: 10.1007/s11064-007-9578-4  0.88
2008 Hamilton KA, Parrish-Aungst S, Margolis FL, Erdélyi F, Szabó G, Puche AC. Sensory deafferentation transsynaptically alters neuronal GluR1 expression in the external plexiform layer of the adult mouse main olfactory bulb. Chemical Senses. 33: 201-10. PMID 18184638 DOI: 10.1093/chemse/bjm079  0.88
2008 De Marchis S, Bovetti S, Carletti B, Hsieh YC, Garzotto D, Peretto P, Fasolo A, Puche AC, Rossi F. Generation of distinct types of periglomerular olfactory bulb interneurons during development and in adult mice: Implication for intrinsic properties of the subventricular zone progenitor population (Journal of Neuroscience (January 17, 2007) (657-664)) Journal of Neuroscience. 28: 1P.  0.88
2007 Puche AC, Baker H. Olfactory cell derivation and migration. Journal of Molecular Histology. 38: 513-5. PMID 17879131 DOI: 10.1007/s10735-007-9140-3  0.88
2007 Zaghetto AA, Paina S, Mantero S, Platonova N, Peretto P, Bovetti S, Puche A, Piccolo S, Merlo GR. Activation of the Wnt-βcatenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections Journal of Neuroscience. 27: 9757-9768. PMID 17804636 DOI: 10.1523/JNEUROSCI.0763-07.2007  0.88
2007 Bovetti S, Hsieh YC, Bovolin P, Perroteau I, Kazunori T, Puche AC. Blood vessels form a scaffold for neuroblast migration in the adult olfactory bulb. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5976-80. PMID 17537968 DOI: 10.1523/JNEUROSCI.0678-07.2007  0.88
2007 Cole LE, Shirey KA, Barry E, Santiago A, Rallabhandi P, Elkins KL, Puche AC, Michalek SM, Vogel SN. Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages. Infection and Immunity. 75: 4127-37. PMID 17517865 DOI: 10.1128/IAI.01868-06  0.88
2007 Bernstein SL, Guo Y, Slater BJ, Puche A, Kelman SE. Neuron stress and loss following rodent anterior ischemic optic neuropathy in double-reporter transgenic mice. Investigative Ophthalmology & Visual Science. 48: 2304-10. PMID 17460295 DOI: 10.1167/iovs.06-0486  0.88
2007 Bovetti S, Bovolin P, Perroteau I, Puche AC. Subventricular zone-derived neuroblast migration to the olfactory bulb is modulated by matrix remodelling. The European Journal of Neuroscience. 25: 2021-33. PMID 17439490 DOI: 10.1111/j.1460-9568.2007.05441.x  0.88
2007 Parrish-Aungst S, Shipley MT, Erdelyi F, Szabo G, Puche AC. Quantitative analysis of neuronal diversity in the mouse olfactory bulb. The Journal of Comparative Neurology. 501: 825-36. PMID 17311323 DOI: 10.1002/cne.21205  0.88
2007 De Marchis S, Bovetti S, Carletti B, Hsieh YC, Garzotto D, Peretto P, Fasolo A, Puche AC, Rossi F. Generation of distinct types of periglomerular olfactory bulb interneurons during development and in adult mice: implication for intrinsic properties of the subventricular zone progenitor population. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 657-64. PMID 17234597 DOI: 10.1523/JNEUROSCI.2870-06.2007  0.88
2007 Laaris N, Puche A, Ennis M. Complementary postsynaptic activity patterns elicited in olfactory bulb by stimulation of mitral/tufted and centrifugal fiber inputs to granule cells Journal of Neurophysiology. 97: 296-306. PMID 17035366 DOI: 10.1152/jn.00823.2006  0.88
2006 Kim HH, Puche AC, Margolis FL. Odorant deprivation reversibly modulates transsynaptic changes in the NR2B-mediated CREB pathway in mouse piriform cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9548-59. PMID 16971539 DOI: 10.1523/JNEUROSCI.1727-06.2006  0.88
2006 Bovetti S, De Marchis S, Gambarotta G, Fasolo A, Perroteau I, Puche AC, Bovolin P. Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Brain Research. 1077: 37-47. PMID 16488402 DOI: 10.1016/j.brainres.2006.01.034  0.88
2005 Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F. Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Molecular and Cellular Biology. 25: 5699-711. PMID 15964824 DOI: 10.1128/MCB.25.13.5699-5711.2005  0.88
2005 Wachowiak M, McGann JP, Heyward PM, Shao Z, Puche AC, Shipley MT. Inhibition [corrected] of olfactory receptor neuron input to olfactory bulb glomeruli mediated by suppression of presynaptic calcium influx. Journal of Neurophysiology. 94: 2700-12. PMID 15917320 DOI: 10.1152/jn.00286.2005  0.88
2004 De Marchis S, Temoney S, Erdelyi F, Bovetti S, Bovolin P, Szabo G, Puche AC. GABAergic phenotypic differentiation of a subpopulation of subventricular derived migrating progenitors. The European Journal of Neuroscience. 20: 1307-17. PMID 15341602 DOI: 10.1111/j.1460-9568.2004.03584.x  0.88
2004 De Marchis S, Fasolo A, Puche AC. Subventricular zone-derived neuronal progenitors migrate into the subcortical forebrain of postnatal mice. The Journal of Comparative Neurology. 476: 290-300. PMID 15269971 DOI: 10.1002/cne.20217  0.88
2004 Priest CA, Puche AC. GABAB receptor expression and function in olfactory receptor neuron axon growth. Journal of Neurobiology. 60: 154-65. PMID 15266647 DOI: 10.1002/neu.20011  0.88
2004 Puche AC, Heyward P, Shipley MT. Transmembrane dye labeling and immunohistochemical staining of electrophysiologically characterized single neurons. Journal of Neuroscience Methods. 137: 235-40. PMID 15262066 DOI: 10.1016/j.jneumeth.2004.02.032  0.88
2004 Shipley MT, Ennis M, Puche AC. Olfactory System The Rat Nervous System. 923-964. DOI: 10.1016/B978-012547638-6/50030-4  0.88
2003 Aungst JL, Heyward PM, Puche AC, Karnup SV, Hayar A, Szabo G, Shipley MT. Centre-surround inhibition among olfactory bulb glomeruli. Nature. 426: 623-9. PMID 14668854 DOI: 10.1038/nature02185  0.88
2003 Shu T, Puche AC, Richards LJ. Development of midline glial populations at the corticoseptal boundary. Journal of Neurobiology. 57: 81-94. PMID 12973830 DOI: 10.1002/neu.10252  0.88
2003 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR. The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Molecular and Cellular Neurosciences. 22: 530-43. PMID 12727448 DOI: 10.1016/S1044-7431(02)00041-6  0.88
2002 Del Punta K, Puche A, Adams NC, Rodriguez I, Mombaerts P. A divergent pattern of sensory axonal projections is rendered convergent by second-order neurons in the accessory olfactory bulb. Neuron. 35: 1057-66. PMID 12354396 DOI: 10.1016/S0896-6273(02)00904-2  0.88
2001 De Marchis S, Fasolo A, Shipley M, Puche A. Unique neuronal tracers show migration and differentiation of SVZ progenitors in organotypic slices Journal of Neurobiology. 49: 326-338. PMID 11745668 DOI: 10.1002/neu.10012  0.88
2001 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T. Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. The Journal of Comparative Neurology. 434: 13-28. PMID 11329126 DOI: 10.1002/cne.1161  0.88
2000 Williams-Hogarth LC, Puche AC, Torrey C, Cai X, Song I, Kolodkin AL, Shipley MT, Ronnett GV. Expression of semaphorins in developing and regenerating olfactory epithelium. The Journal of Comparative Neurology. 423: 565-78. PMID 10880988 DOI: 10.1002/1096-9861(20000807)423:4<565::AID-CNE3>3.0.CO;2-F  0.88
2000 Leinders-Zufall T, Lane AP, Puche AC, Ma W, Novotny MV, Shipley MT, Zufall F. Ultrasensitive pheromone detection by mammalian vomeronasal neurons. Nature. 405: 792-6. PMID 10866200 DOI: 10.1038/35015572  0.88
1999 Bailey MS, Puche AC, Shipley MT. Development of the olfactory bulb: evidence for glia-neuron interactions in glomerular formation. The Journal of Comparative Neurology. 415: 423-48. PMID 10570454 DOI: 10.1002/(SICI)1096-9861(19991227)415:4<423::AID-CNE2>3.0.CO;2-G  0.88
1999 Koster NL, Norman AB, Richtand NM, Nickell WT, Puche AC, Pixley SK, Shipley MT. Olfactory receptor neurons express D2 dopamine receptors. The Journal of Comparative Neurology. 411: 666-73. PMID 10421875 DOI: 10.1002/(SICI)1096-9861(19990906)411:4<666::AID-CNE10>3.0.CO;2-S  0.88
1999 Puche AC, Shipley MT. Odor-induced, activity-dependent transneuronal gene induction in vitro: mediation by NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1359-70. PMID 9952413  0.88
1998 Tenne-Brown J, Puche AC, Key B. Expression of galectin-1 in the mouse olfactory system. The International Journal of Developmental Biology. 42: 791-9. PMID 9727835  0.88
1997 Puche AC, Bartlett PF, Key B. Substrate-bound carbohydrates stimulate signal transduction and neurite outgrowth in an olfactory neuron cell line. Neuroreport. 8: 3183-8. PMID 9351640  0.88
1997 Dowsing B, Puche A, Hearn C, Key B. Presence of novel N-CAM glycoforms in the rat olfactory system Journal of Neurobiology. 32: 659-670. PMID 9183744 DOI: 10.1002/(SICI)1097-4695(19970620)32:7<659::AID-NEU2>3.0.CO;2-3  0.88
1997 Key B, Puche AC. Role of galectin-1 in the olfactory nervous system Trends in Glycoscience and Glycotechnology. 9: 41-45.  0.88
1996 Puche AC, Poirier F, Hair M, Bartlett PF, Key B. Role of galectin-1 in the developing mouse olfactory system. Developmental Biology. 179: 274-87. PMID 8873770 DOI: 10.1006/dbio.1996.0257  0.88
1996 Puche AC, Key B. N-acetyl-lactosamine in the rat olfactory system: expression and potential role in neurite growth. The Journal of Comparative Neurology. 364: 267-78. PMID 8788249 DOI: 10.1002/(SICI)1096-9861(19960108)364:2<267::AID-CNE6>3.0.CO;2-3  0.88
1995 Puche AC, Key B. Identification of cells expressing galectin-1, a galactose-binding receptor, in the rat olfactory system. The Journal of Comparative Neurology. 357: 513-23. PMID 7673482 DOI: 10.1002/cne.903570403  0.88
1995 Richards LJ, Murphy M, Dutton R, Kilpatrick TJ, Puche AC, Key B, Tan SS, Talman PS, Bartlett PF. Lineage specification of neuronal precursors in the mouse spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 92: 10079-83. PMID 7479730 DOI: 10.1073/pnas.92.22.10079  0.88
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