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Stephan R. Krutzik, Ph.D. - Publications

Affiliations: 
2003 University of California, Los Angeles, Los Angeles, CA 
Area:
Immunology
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, et al. Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. Journal of Immunology (Baltimore, Md. : 1950). PMID 29610140 DOI: 10.4049/Jimmunol.1701733  0.663
2016 Kibbie J, Teles RM, Wang Z, Hong P, Montoya D, Krutzik S, Lee S, Kwon O, Modlin RL, Cruz D. Jagged1 Instructs Macrophage Differentiation in Leprosy. Plos Pathogens. 12: e1005808. PMID 27532668 DOI: 10.1371/Journal.Ppat.1005808  0.754
2014 Zhen A, Krutzik SR, Levin BR, Kasparian S, Zack JA, Kitchen SG. CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection. Journal of Virology. 88: 9934-46. PMID 24942581 DOI: 10.1128/Jvi.00616-14  0.453
2014 Wheelwright M, Kim EW, Inkeles MS, De Leon A, Pellegrini M, Krutzik SR, Liu PT. All-trans retinoic acid-triggered antimicrobial activity against Mycobacterium tuberculosis is dependent on NPC2. Journal of Immunology (Baltimore, Md. : 1950). 192: 2280-90. PMID 24501203 DOI: 10.4049/Jimmunol.1301686  0.653
2014 Schenk M, Fabri M, Krutzik SR, Lee DJ, Vu DM, Sieling PA, Montoya D, Liu PT, Modlin RL. Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology. 141: 174-80. PMID 24032597 DOI: 10.1111/Imm.12167  0.812
2014 Agak GW, Qin M, Nobe J, Kim MH, Krutzik SR, Tristan GR, Elashoff D, Garbán HJ, Kim J. Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D. The Journal of Investigative Dermatology. 134: 366-73. PMID 23924903 DOI: 10.1038/Jid.2013.334  0.606
2014 Qin M, Pirouz A, Kim MH, Krutzik SR, Garbán HJ, Kim J. Propionibacterium acnes Induces IL-1β secretion via the NLRP3 inflammasome in human monocytes. The Journal of Investigative Dermatology. 134: 381-8. PMID 23884315 DOI: 10.1038/Jid.2013.309  0.598
2013 Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (New York, N.Y.). 339: 1448-53. PMID 23449998 DOI: 10.1126/Science.1233665  0.782
2013 Klug-Micu GM, Stenger S, Sommer A, Liu PT, Krutzik SR, Modlin RL, Fabri M. CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes. Immunology. 139: 121-8. PMID 23289765 DOI: 10.1111/Imm.12062  0.745
2013 Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ. Galectin-3 regulates the innate immune response of human monocytes. The Journal of Infectious Diseases. 207: 947-56. PMID 23255567 DOI: 10.1093/Infdis/Jis920  0.665
2012 Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nature Medicine. 18: 555-63. PMID 22447076 DOI: 10.1038/Nm.2650  0.68
2011 Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, et al. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Science Translational Medicine. 3: 104ra102. PMID 21998409 DOI: 10.1126/Scitranslmed.3003045  0.801
2010 Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL. T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 22593-8. PMID 21149724 DOI: 10.1073/Pnas.1011624108  0.749
2010 Teles RM, Krutzik SR, Ochoa MT, Oliveira RB, Sarno EN, Modlin RL. Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy. Infection and Immunity. 78: 4634-43. PMID 20713631 DOI: 10.1128/Iai.00454-10  0.602
2009 Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, et al. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host & Microbe. 6: 343-53. PMID 19837374 DOI: 10.1016/J.Chom.2009.09.002  0.801
2009 Tanaka M, Krutzik SR, Sieling PA, Lee DJ, Rea TH, Modlin RL. Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 2349-55. PMID 19635920 DOI: 10.4049/Jimmunol.0801683  0.651
2008 Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. Journal of Immunology (Baltimore, Md. : 1950). 181: 7115-20. PMID 18981132 DOI: 10.4049/Jimmunol.181.10.7115  0.741
2008 Sieling PA, Hill PJ, Dobos KM, Brookman K, Kuhlman AM, Fabri M, Krutzik SR, Rea TH, Heaslip DG, Belisle JT, Modlin RL. Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for MHC class II-restricted T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 180: 5833-42. PMID 18424702 DOI: 10.4049/Jimmunol.180.9.5833  0.563
2008 Liu PT, Phan J, Tang D, Kanchanapoomi M, Hall B, Krutzik SR, Kim J. CD209(+) macrophages mediate host defense against Propionibacterium acnes. Journal of Immunology (Baltimore, Md. : 1950). 180: 4919-23. PMID 18354216 DOI: 10.4049/Jimmunol.180.7.4919  0.731
2008 Ochoa MT, Loncaric A, Krutzik SR, Becker TC, Modlin RL. "Dermal dendritic cells" comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages. The Journal of Investigative Dermatology. 128: 2225-31. PMID 18337829 DOI: 10.1038/Jid.2008.56  0.587
2008 Garg A, Barnes PF, Roy S, Quiroga MF, Wu S, García VE, Krutzik SR, Weis SE, Vankayalapati R. Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection. European Journal of Immunology. 38: 459-69. PMID 18203140 DOI: 10.1002/Eji.200737268  0.449
2008 Schenk M, Liu P, Krutzik SR, Montoya D, Modlin RL. IL‐1beta triggers monocytes to differentiate into CD209+ macrophages The Faseb Journal. 22: 539-539. DOI: 10.1096/Fasebj.22.2_Supplement.539  0.747
2008 Tanaka M, Krutzik SR, Sieling PA, Rea TH, Modlin RL. Fc{gamma} receptor activation triggers monocytes to differentiate into immature dendritic cells that promote autologous T cell response The Faseb Journal. 22: 468-468. DOI: 10.1096/Fasebj.22.2_Supplement.468  0.586
2008 Fabri M, Sieling PA, Hill PJ, Dobos KM, Brookman K, Kuhlman AM, Krutzik SR, Rea TH, Heaslip DG, Belisle JT, Modlin RL. Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for antigen presentation to T cells The Faseb Journal. 22: 421-421. DOI: 10.1096/Fasebj.22.2_Supplement.421  0.575
2008 Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Steng S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens (Journal of Immunolgy (2006) 177 (1864-1871)) Journal of Immunology. 180: 664.  0.346
2007 Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 8128-36. PMID 18056355 DOI: 10.4049/Jimmunol.179.12.8128  0.674
2007 Liu PT, Krutzik SR, Modlin RL. Therapeutic implications of the TLR and VDR partnership. Trends in Molecular Medicine. 13: 117-24. PMID 17276732 DOI: 10.1016/J.Molmed.2007.01.006  0.738
2007 Di Nardo A, Braff MH, Taylor KR, Na C, Granstein RD, McInturff JE, Krutzik S, Modlin RL, Gallo RL. Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. Journal of Immunology (Baltimore, Md. : 1950). 178: 1829-34. PMID 17237433 DOI: 10.4049/Jimmunol.178.3.1829  0.635
2007 Francis J, Wreesman S, Yong S, Reigstad K, Krutzik S, Cooper EL. Analysis of the earthworm coelomocyte cell surface for the presence of Toll-like immune receptors European Journal of Soil Biology. 43: S92-S96. DOI: 10.1016/J.Ejsobi.2007.08.011  0.452
2006 Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. Journal of Immunology (Baltimore, Md. : 1950). 177: 1864-71. PMID 16849498 DOI: 10.4049/Jimmunol.177.3.1864  0.731
2006 Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. Journal of Immunology (Baltimore, Md. : 1950). 177: 298-305. PMID 16785525 DOI: 10.4049/Jimmunol.177.1.298  0.737
2006 Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (New York, N.Y.). 311: 1770-3. PMID 16497887 DOI: 10.1126/Science.1123933  0.783
2006 Constantinescu MB, Phan JN, Krutzik SR, Miller LS, Soriano TT, Kim J, Sieling PA. 298 ROLE OF INNATE IMMUNE CELLS IN TUMOR IMMUNOSURVEILLANCE: DENDRITIC CELLS MAY PROMOTE A STRONGER ANTITUMOR RESPONSE THAN MACROPHAGES. Journal of Investigative Medicine. 54: S131.4-S131. DOI: 10.2310/6650.2005.X0004.297  0.33
2006 Liu P, Stenger S, Li H, Wenzel L, Tan B, Krutzik S, Ochoa M, Schauber J, Wu K, Meinken C, Kamen D, Wagner M, Bals R, Steinmeyer A, Zugel U, et al. Vitamin D3–Triggered Antimicrobial Response—Another Pleiotropic Effect beyond Mineral and Bone Metabolism Journal of the American Society of Nephrology. 17: 2949-2953. DOI: 10.1681/Asn.2006091030  0.667
2005 McInturff JE, Wang SJ, Machleidt T, Lin TR, Oren A, Hertz CJ, Krutzik SR, Hart S, Zeh K, Anderson DH, Gallo RL, Modlin RL, Kim J. Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes. The Journal of Investigative Dermatology. 125: 256-63. PMID 16098035 DOI: 10.1111/J.0022-202X.2005.23805.X  0.601
2005 Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nature Medicine. 11: 653-60. PMID 15880118 DOI: 10.1038/Nm1246  0.806
2005 Liu PT, Krutzik SR, Kim J, Modlin RL. Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function. Journal of Immunology (Baltimore, Md. : 1950). 174: 2467-70. PMID 15728448 DOI: 10.4049/Jimmunol.174.5.2467  0.77
2004 Epelman S, Stack D, Bell C, Wong E, Neely GG, Krutzik S, Miyake K, Kubes P, Zbytnuik LD, Ma LL, Xie X, Woods DE, Mody CH. Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs. Journal of Immunology (Baltimore, Md. : 1950). 173: 2031-40. PMID 15265938 DOI: 10.4049/Jimmunol.173.3.2031  0.498
2004 Krutzik SR, Modlin RL. The role of Toll-like receptors in combating mycobacteria. Seminars in Immunology. 16: 35-41. PMID 14751762 DOI: 10.1016/J.Smim.2003.10.005  0.67
2003 Walton KA, Cole AL, Yeh M, Subbanagounder G, Krutzik SR, Modlin RL, Lucas RM, Nakai J, Smart EJ, Vora DK, Berliner JA. Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1197-203. PMID 12775576 DOI: 10.1161/01.Atv.0000079340.80744.B8  0.638
2003 Krutzik SR, Ochoa MT, Sieling PA, Uematsu S, Ng YW, Legaspi A, Liu PT, Cole ST, Godowski PJ, Maeda Y, Sarno EN, Norgard MV, Brennan PJ, Akira S, Rea TH, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nature Medicine. 9: 525-32. PMID 12692544 DOI: 10.1038/Nm864  0.766
2002 Kim J, Ochoa MT, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brightbill HD, Holland D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ, Modlin RL. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. Journal of Immunology (Baltimore, Md. : 1950). 169: 1535-41. PMID 12133981 DOI: 10.4049/Jimmunol.169.3.1535  0.725
2001 Krutzik SR, Sieling PA, Modlin RL. The role of Toll-like receptors in host defense against microbial infection. Current Opinion in Immunology. 13: 104-8. PMID 11154925 DOI: 10.1016/S0952-7915(00)00189-8  0.653
1999 Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (New York, N.Y.). 285: 732-6. PMID 10426995 DOI: 10.1126/Science.285.5428.732  0.777
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