Year |
Citation |
Score |
2022 |
Shahfar H, Du Q, Parupudi A, Shan L, Esfandiary R, Roberts CJ. Electrostatically Driven Protein-Protein Interactions: Quantitative Prediction of Second Osmotic Virial Coefficients to Aid Antibody Design. The Journal of Physical Chemistry Letters. 1366-1372. PMID 35112863 DOI: 10.1021/acs.jpclett.1c03669 |
0.394 |
|
2020 |
Chaturvedi SK, Parupudi A, Juul-Madsen K, Nguyen A, Vorup-Jensen T, Dragulin-Otto S, Zhao H, Esfandiary R, Schuck P. Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions. Mabs. 12: 1810488. PMID 32887536 DOI: 10.1080/19420862.2020.1810488 |
0.375 |
|
2019 |
Larson NR, Wei Y, Prajapati I, Chakraborty A, Peters B, Cavan Kalonia, Hudak S, Choudhary S, Esfandiary R, Dhar P, Schöneich C, Middaugh CR. Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody. Journal of Pharmaceutical Sciences. PMID 31758949 DOI: 10.1016/J.Xphs.2019.10.069 |
0.573 |
|
2019 |
Prajapati I, Peters BH, Larson NR, Wei Y, Choudhary S, Kalonia C, Hudak S, Esfandiary R, Middaugh CR, Schöneich C. Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody-containing formulation. Journal of Pharmaceutical Sciences. PMID 31715179 DOI: 10.1016/J.Xphs.2019.10.068 |
0.458 |
|
2019 |
Austerberry J, Thistlethwaite A, Fisher K, Golovanov AP, Pluen A, Esfandiary R, van der Walle CF, Warwicker J, Derrick JP, Curtis R. Arginine to lysine mutations increase the aggregation stability of a single chain variable fragment through unfolded state interactions. Biochemistry. PMID 31314511 DOI: 10.1021/Acs.Biochem.9B00367 |
0.475 |
|
2019 |
Hu Y, Arora J, Joshi SB, Esfandiary R, Middaugh CR, Weis DD, Volkin DB. Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1. Journal of Pharmaceutical Sciences. PMID 31201906 DOI: 10.1016/J.Xphs.2019.06.005 |
0.62 |
|
2019 |
Hu Y, Toth RT, Joshi SB, Esfandiary R, Middaugh CR, Volkin DB, Weis DD. Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2. Journal of Pharmaceutical Sciences. PMID 31195015 DOI: 10.1016/J.Xphs.2019.06.001 |
0.605 |
|
2018 |
Shan L, Mody N, Sormanni P, Rosenthal K, Damschroder M, Esfandiary R. Developability assessment of engineered monoclonal antibody variants with a complex self-association behavior using complementary analytical and in silico tools. Molecular Pharmaceutics. PMID 30395473 DOI: 10.1021/Acs.Molpharmaceut.8B00867 |
0.381 |
|
2017 |
Toth RT, Pace SE, Mills BJ, Joshi SB, Esfandiary R, Middaugh CR, Weis DD, Volkin DB. Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody. Journal of Pharmaceutical Sciences. PMID 29269271 DOI: 10.1016/J.Xphs.2017.12.009 |
0.557 |
|
2017 |
Toth RT, Mills BJ, Joshi SB, Esfandiary R, Bishop SM, Middaugh CR, Volkin DB, Weis DD. Correction to Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements. Analytical Chemistry. 89: 13673. PMID 29210567 DOI: 10.1021/acs.analchem.7b04690 |
0.401 |
|
2017 |
Pace SE, Joshi SB, Esfandiary R, Stadelman R, Bishop SM, Middaugh CR, Fisher M, Volkin DB. The Use of a GroEL-BLI Biosensor to Rapidly Assess Pre-Aggregate Populations for Antibody Solutions Exhibiting Different Stability Profiles. Journal of Pharmaceutical Sciences. PMID 29037466 DOI: 10.1016/J.Xphs.2017.10.010 |
0.589 |
|
2017 |
Toth Iv RT, Mills BJ, Joshi SB, Esfandiary R, Bishop SM, Middaugh CR, Volkin DB, Weis DD. An Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange Mass Spectrometry Measurements. Analytical Chemistry. PMID 28753295 DOI: 10.1021/Acs.Analchem.7B01396 |
0.545 |
|
2017 |
Goldberg DS, Lewus R, Esfandiary R, Farkas D, Mody N, Day K, Mallik P, Tracka MB, Sealey SK, Samra HS. Utility of High Throughput Screening Techniques to Predict Stability of Monoclonal Antibody Formulations During Early Stage Development. Journal of Pharmaceutical Sciences. PMID 28456733 DOI: 10.1016/J.Xphs.2017.04.039 |
0.353 |
|
2016 |
Arora J, Hu Y, Esfandiary R, Sathish HA, Bishop SM, Joshi SB, Middaugh CR, Volkin DB, Weis DD. Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity. Mabs. 0. PMID 27560842 DOI: 10.1080/19420862.2016.1222342 |
0.637 |
|
2016 |
Geoghegan JC, Fleming R, Damschroder M, Bishop SM, Sathish HA, Esfandiary R. Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering. Mabs. 0. PMID 27050875 DOI: 10.1080/19420862.2016.1171444 |
0.468 |
|
2016 |
Kim JH, Joshi SB, Esfandiary R, Iyer V, Bishop SM, Volkin DB, Middaugh CR. Improved Comparative Signature Diagrams to Evaluate Similarity of Storage Stability Profiles of Different IgG1 mAbs. Journal of Pharmaceutical Sciences. PMID 26886311 DOI: 10.1016/J.Xphs.2016.01.008 |
0.578 |
|
2015 |
Arora J, Hickey JM, Majumdar R, Esfandiary R, Bishop SM, Samra HS, Middaugh CR, Weis DD, Volkin DB. Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody. Mabs. 7: 525-39. PMID 25875351 DOI: 10.1080/19420862.2015.1029217 |
0.611 |
|
2015 |
Majumdar R, Esfandiary R, Bishop SM, Samra HS, Middaugh CR, Volkin DB, Weis DD. Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life. Mabs. 7: 84-95. PMID 25524268 DOI: 10.4161/19420862.2014.985494 |
0.531 |
|
2015 |
Esfandiary R, Parupudi A, Casas-Finet J, Gadre D, Sathish H. Mechanism of reversible self-association of a monoclonal antibody: role of electrostatic and hydrophobic interactions. Journal of Pharmaceutical Sciences. 104: 577-86. PMID 25407315 DOI: 10.1002/Jps.24237 |
0.394 |
|
2014 |
Telikepalli SN, Kumru OS, Kalonia C, Esfandiary R, Joshi SB, Middaugh CR, Volkin DB. Structural characterization of IgG1 mAb aggregates and particles generated under various stress conditions. Journal of Pharmaceutical Sciences. 103: 796-809. PMID 24452866 DOI: 10.1002/Jps.23839 |
0.499 |
|
2013 |
Esfandiary R, Hayes DB, Parupudi A, Casas-Finet J, Bai S, Samra HS, Shah AU, Sathish HA. A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies. Journal of Pharmaceutical Sciences. 102: 62-72. PMID 23150484 DOI: 10.1002/Jps.23369 |
0.371 |
|
2012 |
Iyer V, Hu L, Liyanage MR, Esfandiary R, Reinisch C, Meinke A, Maisonneuve J, Volkin DB, Joshi SB, Middaugh CR. Preformulation characterization of an aluminum salt-adjuvanted trivalent recombinant protein-based vaccine candidate against Streptococcus pneumoniae. Journal of Pharmaceutical Sciences. 101: 3078-90. PMID 22538529 DOI: 10.1002/Jps.23175 |
0.683 |
|
2011 |
Kamerzell TJ, Esfandiary R, Joshi SB, Middaugh CR, Volkin DB. Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development. Advanced Drug Delivery Reviews. 63: 1118-59. PMID 21855584 DOI: 10.1016/J.Addr.2011.07.006 |
0.766 |
|
2011 |
Palm T, Esfandiary R, Gandhi R. The effect of PEGylation on the stability of small therapeutic proteins. Pharmaceutical Development and Technology. 16: 441-8. PMID 21261458 DOI: 10.3109/10837450.2010.535830 |
0.452 |
|
2010 |
Markham AP, Barrett BS, Esfandiary R, Picking WL, Picking WD, Joshi SB, Middaugh CR. Formulation and immunogenicity of a potential multivalent type III secretion system-based protein vaccine. Journal of Pharmaceutical Sciences. 99: 4497-509. PMID 20845449 DOI: 10.1002/Jps.22195 |
0.68 |
|
2010 |
Barrett BS, Markham AP, Esfandiary R, Picking WL, Picking WD, Joshi SB, Middaugh CR. Formulation and immunogenicity studies of type III secretion system needle antigens as vaccine candidates. Journal of Pharmaceutical Sciences. 99: 4488-96. PMID 20845448 DOI: 10.1002/Jps.22180 |
0.67 |
|
2010 |
Esfandiary R, Yee L, Ohtake S, Martin RA, Truong-Le VL, Lechuga-Ballesteros D, Moore DS, Joshi SB, Middaugh CR. Biophysical characterization of rotavirus serotypes G1, G3 and G4. Human Vaccines. 6: 390-8. PMID 20534978 DOI: 10.4161/Hv.6.5.10963 |
0.591 |
|
2009 |
Esfandiary R, Hunjan JS, Lushington GH, Joshi SB, Middaugh CR. Temperature dependent 2nd derivative absorbance spectroscopy of aromatic amino acids as a probe of protein dynamics. Protein Science : a Publication of the Protein Society. 18: 2603-14. PMID 19827094 DOI: 10.1002/Pro.264 |
0.592 |
|
2009 |
Esfandiary R, Kickhoefer VA, Rome LH, Joshi SB, Middaugh CR. Structural stability of vault particles. Journal of Pharmaceutical Sciences. 98: 1376-86. PMID 18683860 DOI: 10.1002/Jps.21508 |
0.52 |
|
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