Vadim Y. Bolshakov - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Website:
http://www.hms.harvard.edu/dms/neuroscience/fac/bolshakov.html

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Carlezon WA, Kim W, Missig G, Finger BC, Landino SM, Alexander AJ, Mokler EL, Robbins JO, Li Y, Bolshakov VY, McDougle CJ, Kim KS. Maternal and early postnatal immune activation produce sex-specific effects on autism-like behaviors and neuroimmune function in mice. Scientific Reports. 9: 16928. PMID 31729416 DOI: 10.1038/s41598-019-53294-z  1
2019 Huang CCY, Muszynski KJ, Bolshakov VY, Balu DT. Deletion of Dtnbp1 in mice impairs threat memory consolidation and is associated with enhanced inhibitory drive in the amygdala. Translational Psychiatry. 9: 132. PMID 30967545 DOI: 10.1038/s41398-019-0465-y  0.32
2018 Luchkina NV, Bolshakov VY. Mechanisms of fear learning and extinction: synaptic plasticity-fear memory connection. Psychopharmacology. PMID 30415278 DOI: 10.1007/s00213-018-5104-4  1
2018 Li Y, Missig G, Finger BC, Landino SM, Alexander AJ, Mokler E, Robbins J, Manasian Y, Kim W, Kim KS, McDougle CJ, Carlezon WA, Bolshakov VY. Maternal and Early Postnatal Immune Activation Produce Dissociable Effects on Neurotransmission in mPFC-Amygdala Circuits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29491010 DOI: 10.1523/JNEUROSCI.3642-17.2018  1
2017 Lee SH, Lutz D, Mossalam M, Bolshakov VY, Frotscher M, Shen J. Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway. Molecular Neurodegeneration. 12: 48. PMID 28619096 DOI: 10.1186/s13024-017-0189-5  0.56
2017 Luchkina NV, Bolshakov VY. Diminishing fear: Optogenetic approach toward understanding neural circuits of fear control. Pharmacology, Biochemistry, and Behavior. PMID 28502746 DOI: 10.1016/j.pbb.2017.05.005  1
2016 Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy JM, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Modulation of anxiety and fear via distinct intrahippocampal circuits. Elife. 5. PMID 26971710 DOI: 10.7554/eLife.14120  0.92
2016 Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT. An mGlu5 Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26741285 DOI: 10.1038/npp.2016.2  1
2016 Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy JM, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Modulation of anxiety and fear via distinct intrahippocampal circuits Elife. 5. DOI: 10.7554/eLife.14120.001  1
2015 Engin E, Zarnowska ED, Benke D, Tsvetkov E, Sigal M, Keist R, Bolshakov VY, Pearce RA, Rudolph U. Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13698-712. PMID 26446222 DOI: 10.1523/JNEUROSCI.1370-15.2015  1
2015 Levy RJ, Kvajo M, Li Y, Tsvetkov E, Dong W, Yoshikawa Y, Kataoka T, Bolshakov VY, Karayiorgou M, Gogos JA. Deletion of Rapgef6, a candidate schizophrenia susceptibility gene, disrupts amygdala function in mice. Translational Psychiatry. 5: e577. PMID 26057047 DOI: 10.1038/tp.2015.75  1
2015 Xia D, Watanabe H, Wu B, Lee SH, Li Y, Tsvetkov E, Bolshakov VY, Shen J, Kelleher RJ. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease. Neuron. 85: 967-81. PMID 25741723 DOI: 10.1016/j.neuron.2015.02.010  1
2014 Cunningham M, Cho JH, Leung A, Savvidis G, Ahn S, Moon M, Lee PK, Han JJ, Azimi N, Kim KS, Bolshakov VY, Chung S. hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice. Cell Stem Cell. 15: 559-73. PMID 25517465 DOI: 10.1016/j.stem.2014.10.006  1
2014 Kim TG, Yao R, Monnell T, Cho JH, Vasudevan A, Koh A, Peeyush KT, Moon M, Datta D, Bolshakov VY, Kim KS, Chung S. Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation. Stem Cells (Dayton, Ohio). 32: 1789-804. PMID 24648391 DOI: 10.1002/stem.1704  1
2014 Riccio A, Li Y, Tsvetkov E, Gapon S, Yao GL, Smith KS, Engin E, Rudolph U, Bolshakov VY, Clapham DE. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3653-67. PMID 24599464 DOI: 10.1523/JNEUROSCI.2274-13.2014  1
2013 Cho JH, Deisseroth K, Bolshakov VY. Synaptic encoding of fear extinction in mPFC-amygdala circuits. Neuron. 80: 1491-507. PMID 24290204 DOI: 10.1016/j.neuron.2013.09.025  1
2013 Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proceedings of the National Academy of Sciences of the United States of America. 110: E2400-9. PMID 23729812 DOI: 10.1073/pnas.1304308110  1
2013 Li Y, Sacchi S, Pollegioni L, Basu AC, Coyle JT, Bolshakov VY. Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level. Nature Communications. 4: 1760. PMID 23612301 DOI: 10.1038/ncomms2779  1
2013 Li Y, Meloni EG, Carlezon WA, Milad MR, Pitman RK, Nader K, Bolshakov VY. Learning and reconsolidation implicate different synaptic mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 110: 4798-803. PMID 23487762 DOI: 10.1073/pnas.1217878110  1
2012 Cho JH, Zushida K, Shumyatsky GP, Carlezon WA, Meloni EG, Bolshakov VY. Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14165-77. PMID 23055486 DOI: 10.1523/JNEUROSCI.1402-12.2012  1
2012 Gisabella B, Bolshakov VY, Benes FM. Kainate receptor-mediated modulation of hippocampal fast spiking interneurons in a rat model of schizophrenia. Plos One. 7: e32483. PMID 22396770 DOI: 10.1371/journal.pone.0032483  1
2012 Benneyworth MA, Li Y, Basu AC, Bolshakov VY, Coyle JT. Cell selective conditional null mutations of serine racemase demonstrate a predominate localization in cortical glutamatergic neurons. Cellular and Molecular Neurobiology. 32: 613-24. PMID 22362148 DOI: 10.1007/s10571-012-9808-4  1
2012 Cho JH, Bayazitov IT, Meloni EG, Myers KM, Carlezon WA, Zakharenko SS, Bolshakov VY. Coactivation of thalamic and cortical pathways induces input timing-dependent plasticity in amygdala. Nature Neuroscience. 15: 113-22. PMID 22158512 DOI: 10.1038/nn.2993  1
2011 Chung S, Moon JI, Leung A, Aldrich D, Lukianov S, Kitayama Y, Park S, Li Y, Bolshakov VY, Lamonerie T, Kim KS. ES cell-derived renewable and functional midbrain dopaminergic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 9703-8. PMID 21606375 DOI: 10.1073/pnas.1016443108  1
2010 Shin RM, Tully K, Li Y, Cho JH, Higuchi M, Suhara T, Bolshakov VY. Hierarchical order of coexisting pre- and postsynaptic forms of long-term potentiation at synapses in amygdala. Proceedings of the National Academy of Sciences of the United States of America. 107: 19073-8. PMID 20956319 DOI: 10.1073/pnas.1009803107  1
2010 Tully K, Bolshakov VY. Emotional enhancement of memory: how norepinephrine enables synaptic plasticity. Molecular Brain. 3: 15. PMID 20465834 DOI: 10.1186/1756-6606-3-15  1
2009 Riccio A, Li Y, Moon J, Kim KS, Smith KS, Rudolph U, Gapon S, Yao GL, Tsvetkov E, Rodig SJ, Van't Veer A, Meloni EG, Carlezon WA, Bolshakov VY, Clapham DE. Essential role for TRPC5 in amygdala function and fear-related behavior. Cell. 137: 761-72. PMID 19450521 DOI: 10.1016/j.cell.2009.03.039  1
2009 Li Y, Krupa B, Kang JS, Bolshakov VY, Liu G. Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns. Journal of Neurophysiology. 102: 578-89. PMID 19439669 DOI: 10.1152/jn.91342.2008  1
2009 Bolshakov VY. Nipping fear in the bud: inhibitory control in the amygdala. Neuron. 61: 817-9. PMID 19323992 DOI: 10.1016/j.neuron.2009.03.004  1
2009 Gisabella B, Cunningham MG, Bolshakov VY, Benes FM. Amygdala-dependent regulation of electrical properties of hippocampal interneurons in a model of schizophrenia. Biological Psychiatry. 65: 464-72. PMID 19027103 DOI: 10.1016/j.biopsych.2008.09.016  1
2008 Pan BX, Vautier F, Ito W, Bolshakov VY, Morozov A. Enhanced cortico-amygdala efficacy and suppressed fear in absence of Rap1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2089-98. PMID 18305243 DOI: 10.1523/JNEUROSCI.5156-07.2008  1
2007 Tully K, Li Y, Bolshakov VY. Keeping in check painful synapses in central amygdala. Neuron. 56: 757-9. PMID 18054852 DOI: 10.1016/j.neuron.2007.11.011  1
2007 Tully K, Li Y, Tsvetkov E, Bolshakov VY. Norepinephrine enables the induction of associative long-term potentiation at thalamo-amygdala synapses. Proceedings of the National Academy of Sciences of the United States of America. 104: 14146-50. PMID 17709755 DOI: 10.1073/pnas.0704621104  1
2007 Bolshakov VY. SCOPing out proteases in long-term memory. Cell. 128: 1029-30. PMID 17382874 DOI: 10.1016/j.cell.2007.02.034  1
2006 Shin RM, Tsvetkov E, Bolshakov VY. Spatiotemporal asymmetry of associative synaptic plasticity in fear conditioning pathways. Neuron. 52: 883-96. PMID 17145508 DOI: 10.1016/j.neuron.2006.10.010  1
2006 Kodirov SA, Takizawa S, Joseph J, Kandel ER, Shumyatsky GP, Bolshakov VY. Synaptically released zinc gates long-term potentiation in fear conditioning pathways. Proceedings of the National Academy of Sciences of the United States of America. 103: 15218-23. PMID 17005717 DOI: 10.1073/pnas.0607131103  1
2006 Goussakov I, Chartoff EH, Tsvetkov E, Gerety LP, Meloni EG, Carlezon WA, Bolshakov VY. LTP in the lateral amygdala during cocaine withdrawal. The European Journal of Neuroscience. 23: 239-50. PMID 16420433 DOI: 10.1111/j.1460-9568.2005.04538.x  1
2005 Shumyatsky GP, Malleret G, Shin RM, Takizawa S, Tully K, Tsvetkov E, Zakharenko SS, Joseph J, Vronskaya S, Yin D, Schubart UK, Kandel ER, Bolshakov VY. stathmin, a gene enriched in the amygdala, controls both learned and innate fear. Cell. 123: 697-709. PMID 16286011 DOI: 10.1016/j.cell.2005.08.038  1
2005 Gisabella B, Bolshakov VY, Benes FM. Regulation of synaptic plasticity in a schizophrenia model. Proceedings of the National Academy of Sciences of the United States of America. 102: 13301-6. PMID 16131546 DOI: 10.1073/pnas.0506034102  1
2005 Dityatev AE, Bolshakov VY. Amygdala, long-term potentiation, and fear conditioning. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 75-88. PMID 15632280 DOI: 10.1177/1073858404270857  1
2004 Tsvetkov E, Shin RM, Bolshakov VY. Glutamate uptake determines pathway specificity of long-term potentiation in the neural circuitry of fear conditioning. Neuron. 41: 139-51. PMID 14715141 DOI: 10.1016/S0896-6273(03)00800-6  1
2003 Feinmark SJ, Begum R, Tsvetkov E, Goussakov I, Funk CD, Siegelbaum SA, Bolshakov VY. 12-lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11427-35. PMID 14673007  1
2003 Hinds HL, Goussakov I, Nakazawa K, Tonegawa S, Bolshakov VY. Essential function of alpha-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse. Proceedings of the National Academy of Sciences of the United States of America. 100: 4275-80. PMID 12629219 DOI: 10.1073/pnas.0530202100  1
2002 Shumyatsky GP, Tsvetkov E, Malleret G, Vronskaya S, Hatton M, Hampton L, Battey JF, Dulac C, Kandel ER, Bolshakov VY. Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell. 111: 905-18. PMID 12526815 DOI: 10.1016/S0092-8674(02)01116-9  1
2002 Tsvetkov E, Carlezon WA, Benes FM, Kandel ER, Bolshakov VY. Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala. Neuron. 34: 289-300. PMID 11970870 DOI: 10.1016/S0896-6273(02)00645-1  1
2000 Bolshakov VY, Carboni L, Cobb MH, Siegelbaum SA, Belardetti F. Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nature Neuroscience. 3: 1107-12. PMID 11036267 DOI: 10.1038/80624  1
1999 Janz R, Südhof TC, Hammer RE, Unni V, Siegelbaum SA, Bolshakov VY. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 24: 687-700. PMID 10595519  1
1997 Bolshakov VY, Golan H, Kandel ER, Siegelbaum SA. Recruitment of new sites of synaptic transmission during the cAMP-dependent late phase of LTP at CA3-CA1 synapses in the hippocampus. Neuron. 19: 635-51. PMID 9331354 DOI: 10.1016/S0896-6273(00)80377-3  1
1996 Siegelbaum SA, Bolshakov VY. Response: Long-Term Potentiation in the CA1 Hippocampus. Science (New York, N.Y.). 271: 1605-6. PMID 17840522 DOI: 10.1126/science.271.5255.1605  1
1996 McMahon HT, Bolshakov VY, Janz R, Hammer RE, Siegelbaum SA, Südhof TC. Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. 93: 4760-4. PMID 8643476 DOI: 10.1073/pnas.93.10.4760  1
1995 Bolshakov VY, Siegelbaum SA. Hippocampal long-term depression: arachidonic acid as a potential retrograde messenger. Neuropharmacology. 34: 1581-7. PMID 8606806 DOI: 10.1016/0028-3908(95)00127-R  1
1995 Bolshakov VY, Siegelbaum SA. Regulation of hippocampal transmitter release during development and long-term potentiation. Science (New York, N.Y.). 269: 1730-4. PMID 7569903  1
1994 Geppert M, Bolshakov VY, Siegelbaum SA, Takei K, De Camilli P, Hammer RE, Südhof TC. The role of Rab3A in neurotransmitter release. Nature. 369: 493-7. PMID 7911226 DOI: 10.1038/369493a0  1
1994 Bolshakov VY, Siegelbaum SA. Postsynaptic induction and presynaptic expression of hippocampal long-term depression. Science (New York, N.Y.). 264: 1148-52. PMID 7909958  1
1992 Bolshakov VYu, Gapon SA, Magazanik LG. Transduction mechanism for glutamate-induced potassium current in neurones of the mollusc Planorbarius corneus. The Journal of Physiology. 455: 33-50. PMID 1362443  1
1991 Bolshakov VYu, Gapon SA, Magazanik LG. Different types of glutamate receptors in isolated and identified neurones of the mollusc Planorbarius corneus. The Journal of Physiology. 439: 15-35. PMID 1654412  1
1988 Lukomskaya Ya. N, Bolshakov VY, Samoilova MV. Comparative study of synaptic transmission in rabbit and frog sympathetic ganglia after acetylcholinesterase inhibition Zhurnal Evolyutsionnoi Biokhimii I Fiziologii. 24: 668-678. PMID 2851243  1
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