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Nick A. Paras - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Medicinal Chemistry
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ. Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics. Nature Machine Intelligence. 4: 583-595. PMID 36276634 DOI: 10.1038/s42256-022-00490-8  0.419
2021 Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent. Organic Letters. PMID 33929208 DOI: 10.1021/acs.orglett.1c00871  0.484
2021 Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles. Acs Omega. 6: 9804-9812. PMID 33869960 DOI: 10.1021/acsomega.1c00458  0.525
2020 Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J. Selectivity in the Addition of Electron Deficient Radicals to the 2 Position of Indoles. European Journal of Organic Chemistry. 2020: 5828-5832. PMID 33692651 DOI: 10.1002/Ejoc.201901784  0.476
2020 Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, ... ... Paras NA, et al. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. Acs Medicinal Chemistry Letters. 11: 127-132. PMID 32071678 DOI: 10.1021/Acsmedchemlett.9B00480  0.471
2018 Caenepeel S, Brown SP, Belmontes B, Moody G, Keegan KS, Chui D, Whittington DA, Huang X, Poppe L, Cheng AC, Cardozo M, Houze J, Li Y, Lucas B, Paras NA, et al. AMG 176, a Selective MCL1 Inhibitor, is Effective in Hematological Cancer Models Alone and in Combination with Established Therapies. Cancer Discovery. PMID 30254093 DOI: 10.1158/2159-8290.Cd-18-0387  0.475
2018 O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J. Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism. The Journal of Organic Chemistry. PMID 29940725 DOI: 10.1021/Acs.Joc.8B01146  0.603
2014 Johnson MG, Gribble MW, Houze JB, Paras NA. Convenient route to secondary sulfinates: application to the stereospecific synthesis of α-C-chiral sulfonamides. Organic Letters. 16: 6248-51. PMID 25415837 DOI: 10.1021/Ol503208Z  0.395
2010 EVANS DA, BURGEY CS, PARAS NA, VOJKOVSKY T, TREGAY SW. ChemInform Abstract: C2-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Enantioselective Catalysis of the Glyoxylate-Ene Reaction. Cheminform. 29: no-no. DOI: 10.1002/chin.199844036  0.532
2009 Paras NA, Simmons B, MacMillan DWC. A process for the rapid removal of dialkylamino-substituents from aromatic rings. Application to the expedient synthesis of (R)-tolterodine Tetrahedron. 65: 3232-3238. DOI: 10.1016/J.Tet.2008.12.054  0.59
2004 Bunin BA, Dener JM, Kelly DE, Paras NA, Tario JD, Tushup SP. Solid-phase synthesis of 1-substituted tetrahydroisoquinoline derivatives employing BOC-protected tetrahydroisoquinoline carboxylic acids. Journal of Combinatorial Chemistry. 6: 487-96. PMID 15244409 DOI: 10.1021/Cc0340776  0.407
2002 Paras NA, MacMillan DW. The enantioselective organocatalytic 1,4-addition of electron-rich benzenes to alpha,beta-unsaturated aldehydes. Journal of the American Chemical Society. 124: 7894-5. PMID 12095321 DOI: 10.1021/Ja025981P  0.623
2001 Paras NA, MacMillan DW. New strategies in organic catalysis: the first enantioselective organocatalytic Friedel-Crafts alkylation. Journal of the American Chemical Society. 123: 4370-1. PMID 11457218 DOI: 10.1021/Ja015717G  0.619
2000 Evans DA, Tregay SW, Burgey CS, Paras NA, Vojkovsky T. C2-symmetric copper(II) complexes as chiral lewis acids. Catalytic enantioselective carbonyl - Ene reactions with glyoxylate and pyruvate esters Journal of the American Chemical Society. 122: 7936-7943. DOI: 10.1021/Ja000913T  0.562
2000 Evans DA, Tregay SW, Burgey CS, Paras NA, Vojkovsky T. ChemInform Abstract: C2-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Catalytic Enantioselective Carbonyl-Ene Reactions with Glyoxylate and Pyruvate Esters. Cheminform. 31: no-no. DOI: 10.1002/chin.200049032  0.554
1998 Evans DA, Burgey CS, Paras NA, Vojkovsky T, Tregay SW. C2-symmetric copper(II) complexes as chiral Lewis acids. Enantioselective catalysis of the glyoxylate - Ene reaction [10] Journal of the American Chemical Society. 120: 5824-5825. DOI: 10.1021/Ja980549M  0.609
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