Christine McDonald, Ph.D. - Publications

Affiliations: 
1995-2001 Pathology Stony Brook University, Stony Brook, NY, United States 
 2001-2006 Pathology University of Michigan, Ann Arbor, Ann Arbor, MI 
 2006-2018 Pathobiology The Cleveland Clinic, Cleveland, OH, United States 
 2018- Inflammation & Immunity The Cleveland Clinic, Cleveland, OH, United States 
Area:
Molecular Biology, Innate Immunity, Host Response to Infection, Inflammatory Bowel Disease,Pathology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... McDonald C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.371
2020 Farabaugh KT, Krokowski D, Guan BJ, Gao Z, Gao XH, Wu J, Jobava R, Ray G, de Jesus TJ, Bianchi MG, Chukwurah E, Bussolati O, Kilberg M, Buchner DA, Sen GC, ... ... McDonald C, et al. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. Elife. 9. PMID 32175843 DOI: 10.7554/Elife.52241  0.39
2020 Billi AC, Ludwig JE, Fritz Y, Rozic R, Swindell WR, Tsoi LC, Gruszka D, Abdollahi-Roodsaz S, Xing X, Diaconu D, Uppala R, Camhi MI, Klenotic PA, Sarkar MK, Husni ME, ... ... McDonald C, et al. KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. The Journal of Clinical Investigation. PMID 32155135 DOI: 10.1172/Jci133159  0.321
2020 Scheraga RG, Abraham S, Grove LM, Southern BD, Crish JF, Perelas A, McDonald C, Asosingh K, Hasday JD, Olman MA. TRPV4 Protects the Lung from Bacterial Pneumonia via MAPK Molecular Pathway Switching. Journal of Immunology (Baltimore, Md. : 1950). PMID 31969384 DOI: 10.4049/Jimmunol.1901033  0.379
2015 Nickerson KP, Chanin R, McDonald C. Deregulation of intestinal anti-microbial defense by the dietary additive, maltodextrin Gut Microbes. 6: 78-83. PMID 25738413 DOI: 10.1080/19490976.2015.1005477  0.326
2014 Warner N, Burberry A, Pliakas M, McDonald C, Núñez G. A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. The Journal of Biological Chemistry. 289: 28213-24. PMID 25170077 DOI: 10.1074/Jbc.M114.574756  0.689
2014 Homer CR, Nickerson KP, Corridoni D, Kabi A, Cominelli F, McDonald C. Sa1765 Defective Autophagy Contributes to Impaired Bacterial Clearance of SAMP1/YITFC Mice Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61036-2  0.395
2013 Tang H, Amara U, Tang D, Barnes MA, McDonald C, Nagy LE. Synergistic interaction between C5a and NOD2 signaling in the regulation of chemokine expression in RAW 264.7 macrophages. Advances in Bioscience and Biotechnology (Print). 4: 30-37. PMID 24634797 DOI: 10.4236/Abb.2013.48A3004  0.343
2013 Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F. Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16999-7004. PMID 24082103 DOI: 10.1073/Pnas.1311657110  0.385
2013 Warner N, Burberry A, Franchi L, Kim YG, McDonald C, Sartor MA, Núñez G. A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Science Signaling. 6: rs3. PMID 23322906 DOI: 10.1126/Scisignal.2003305  0.697
2013 Schirbel A, Kessler S, Rieder F, West G, Rebert N, Asosingh K, McDonald C, Fiocchi C. Pro-angiogenic activity of TLRs and NLRs: a novel link between gut microbiota and intestinal angiogenesis. Gastroenterology. 144: 613-623.e9. PMID 23149220 DOI: 10.1053/J.Gastro.2012.11.005  0.345
2012 Nickerson KP, McDonald C. Crohn's disease-associated adherent-invasive Escherichia coli adhesion is enhanced by exposure to the ubiquitous dietary polysaccharide maltodextrin. Plos One. 7: e52132. PMID 23251695 DOI: 10.1371/Journal.Pone.0052132  0.307
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... McDonald C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.453
2012 Homer CR, Kabi A, Marina-García N, Sreekumar A, Nesvizhskii AI, Nickerson KP, Chinnaiyan AM, Nuñez G, McDonald C. A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy. The Journal of Biological Chemistry. 287: 25565-76. PMID 22665475 DOI: 10.1074/Jbc.M111.326835  0.59
2012 Marinis JM, Hutti JE, Homer CR, Cobb BA, Cantley LC, McDonald C, Abbott DW. IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling. Molecular and Cellular Biology. 32: 2479-89. PMID 22547678 DOI: 10.1128/Mcb.00106-12  0.422
2012 Richmond AL, Kabi A, Homer CR, Marina-García N, Nickerson KP, Nesvizhskii AI, Sreekumar A, Chinnaiyan AM, Nuñez G, McDonald C. The nucleotide synthesis enzyme CAD inhibits NOD2 antibacterial function in human intestinal epithelial cells. Gastroenterology. 142: 1483-92.e6. PMID 22387394 DOI: 10.1053/J.Gastro.2012.02.040  0.54
2012 Richmond AL, Kabi A, Homer CR, Nickerson KP, Nesvizhskii AI, Sreekumar A, Chinnaiyan A, Nunez G, McDonald C. 360 CAD, a Nucleotide Synthesis Enzyme, Inhibits NOD2 Anti-Bacterial Function in Human Intestinal Epithelial Cells Gastroenterology. 142: S-85. DOI: 10.1016/S0016-5085(12)60321-7  0.496
2011 Marinis JM, Homer CR, McDonald C, Abbott DW. A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses. The Journal of Biological Chemistry. 286: 1938-50. PMID 21097508 DOI: 10.1074/Jbc.M110.189308  0.478
2010 Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology. 139: 1630-41, 1641.e1-2. PMID 20637199 DOI: 10.1053/J.Gastro.2010.07.006  0.312
2010 Schirbel A, Rieder F, Scaldaferri F, Phillips M, West G, McDonald C, Fiocchi C. 504 Induction of Angiogenesis by Distinct Toll-Like (TLR) and NOD-Like (NLR) Receptors: Evidence for Bacteria-Mediated Angiogenesis in IBD Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)60330-7  0.313
2008 Marina-García N, Franchi L, Kim YG, Miller D, McDonald C, Boons GJ, Núñez G. Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2. Journal of Immunology (Baltimore, Md. : 1950). 180: 4050-7. PMID 18322214  0.497
2008 Scaldaferri F, Phillips M, Rhee M, West G, Kessler S, McDonald C, Fiocchi C. T1259 Mucosal Non-Immune Cells Produce Pro-Inflammatory Mediators in Response to Toll-Like (TLRS) and NOD-Like Receptor (NLRS) Ligands: Mesenchymal and Endothelial Cells As Novel Players of the Gut Innate Immunity Response Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62416-6  0.328
2007 Lécine P, Esmiol S, Métais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP, Ollendorff V. The NOD2-RICK complex signals from the plasma membrane. The Journal of Biological Chemistry. 282: 15197-207. PMID 17355968 DOI: 10.1074/Jbc.M606242200  0.554
2007 Park JH, Kim YG, McDonald C, Kanneganti TD, Hasegawa M, Body-Malapel M, Inohara N, Núñez G. RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs Journal of Immunology. 178: 2380-2386. PMID 17277144 DOI: 10.4049/Jimmunol.178.4.2380  0.55
2006 Franchi L, McDonald C, Kanneganti TD, Amer A, Núñez G. Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense. Journal of Immunology (Baltimore, Md. : 1950). 177: 3507-13. PMID 16951308 DOI: 10.4049/Jimmunol.177.6.3507  0.559
2005 McDonald C, Chen FF, Ollendorff V, Ogura Y, Marchetto S, Lécine P, Borg JP, Nuñez G. A role for Erbin in the regulation of Nod2-dependent NF-κB signaling Journal of Biological Chemistry. 280: 40301-40309. PMID 16203728 DOI: 10.1074/Jbc.M508538200  0.631
2005 Inohara N, Chamaillard M, McDonald C, Nuñez G. NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease Annual Review of Biochemistry. 74: 355-383. PMID 15952891 DOI: 10.1146/Annurev.Biochem.74.082803.133347  0.581
2005 McDonald CL, Inohara N, Nuñez G. Peptidoglycan Signaling in Innate Immunity and Inflammatory Disease Journal of Biological Chemistry. 280: 20177-20180. PMID 15802263 DOI: 10.1074/Jbc.R500001200  0.535
2005 Chamaillard M, McDonald C, Nuñez G. Early-onset sarcoidosis gets the nod Blood. 105: 912-912. DOI: 10.1182/Blood-2004-11-4289  0.459
2004 McDonald C, Vanscoy S, Hearing P, Reich NC. Induction of genes involved in cell cycle progression by interleukin-4. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 729-38. PMID 15684740 DOI: 10.1089/Jir.2004.24.729  0.607
2004 McDonald CL, Nuñez G. Mindin the fort. Nature Immunology. 5: 16-18. PMID 14699402 DOI: 10.1038/Ni0104-16  0.414
2003 McDonald C, Vacratsis PO, Bliska JB, Dixon JE. The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. The Journal of Biological Chemistry. 278: 18514-23. PMID 12626518 DOI: 10.1074/Jbc.M301226200  0.544
2002 McBride KM, Banninger G, McDonald C, Reich NC. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha. The Embo Journal. 21: 1754-63. PMID 11927559 DOI: 10.1093/Emboj/21.7.1754  0.64
2000 McBride KM, McDonald C, Reich NC. Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor. The Embo Journal. 19: 6196-206. PMID 11080165 DOI: 10.1093/Emboj/19.22.6196  0.729
1999 McDonald C, Reich NC. Cooperation of the transcriptional coactivators CBP and p300 with Stat6 Journal of Interferon and Cytokine Research. 19: 711-722. PMID 10454341 DOI: 10.1089/107999099313550  0.544
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