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William A. Barton, Ph.D. - Publications

Affiliations: 
2002 Weill Cornell Medical College, New York, NY, United States 
Area:
Molecular Biology, Biochemistry
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Suliman M, Santosh V, Seegar TCM, Dalton AC, Schultz KM, Klug CS, Barton WA. Directed evolution provides insight into conformational substrate sampling by SrtA. Plos One. 12: e0184271. PMID 28859178 DOI: 10.1371/Journal.Pone.0184271  0.463
2017 Shlamkovich T, Aharon L, Barton WA, Papo N. Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapy. Oncotarget. PMID 28422724 DOI: 10.18632/Oncotarget.16827  0.413
2016 Dalton AC, Shlamkovitch T, Papo N, Barton WA. Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. Plos One. 11: e0163732. PMID 27695111 DOI: 10.1371/Journal.Pone.0163732  0.42
2014 Dalton AC, Barton WA. Over-expression of secreted proteins from mammalian cell lines Protein Science. 23: 517-525. PMID 24510886 DOI: 10.1002/Pro.2439  0.336
2014 Barton WA, Dalton AC, Seegar TCM, Himanen JP, Nikolov DB. Tie2 and Eph receptor tyrosine kinase activation and signaling Cold Spring Harbor Perspectives in Biology. 6. PMID 24478383 DOI: 10.1101/Cshperspect.A009142  0.65
2013 Yu X, Seegar TC, Dalton AC, Tzvetkova-Robev D, Goldgur Y, Rajashankar KR, Nikolov DB, Barton WA. Structural basis for angiopoietin-1-mediated signaling initiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 7205-10. PMID 23592718 DOI: 10.1073/Pnas.1216890110  0.722
2010 Seegar T, Barton W. Imaging protein-protein interactions in vivo. Journal of Visualized Experiments : Jove. PMID 20972411 DOI: 10.3791/2149  0.356
2010 Song Y, Dilger E, Bell J, Barton WA, Fang X. Large scale purification and characterization of recombinant human autotaxin/lysophospholipase D from mammalian cells. Bmb Reports. 43: 541-6. PMID 20797316 DOI: 10.5483/Bmbrep.2010.43.8.541  0.412
2010 Seegar TC, Eller B, Tzvetkova-Robev D, Kolev MV, Henderson SC, Nikolov DB, Barton WA. Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands. Molecular Cell. 37: 643-55. PMID 20227369 DOI: 10.1016/J.Molcel.2010.02.007  0.636
2006 Barton WA, Tzvetkova-Robev D, Erdjument-Bromage H, Tempst P, Nikolov DB. Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells. Protein Science : a Publication of the Protein Society. 15: 2008-13. PMID 16823037 DOI: 10.1110/Ps.062244206  0.588
2006 Barton WA, Tzvetkova-Robev D, Miranda EP, Kolev MV, Rajashankar KR, Himanen JP, Nikolov DB. Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex. Nature Structural & Molecular Biology. 13: 524-32. PMID 16732286 DOI: 10.1038/Nsmb1101  0.675
2005 Janes PW, Saha N, Barton WA, Kolev MV, Wimmer-Kleikamp SH, Nievergall E, Blobel CP, Himanen JP, Lackmann M, Nikolov DB. Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell. 123: 291-304. PMID 16239146 DOI: 10.1016/J.Cell.2005.08.014  0.629
2005 Nikolov DB, Li C, Barton WA, Himanen JP. Crystal structure of the ephrin-B1 ectodomain: implications for receptor recognition and signaling. Biochemistry. 44: 10947-53. PMID 16101278 DOI: 10.1021/Bi050789W  0.642
2005 Barton WA, Tzvetkova D, Nikolov DB. Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition. Structure (London, England : 1993). 13: 825-32. PMID 15893672 DOI: 10.1016/J.Str.2005.03.009  0.672
2004 Barton WA, Himanen JP, Antipenko A, Nikolov DB. Structures of axon guidance molecules and their neuronal receptors. Advances in Protein Chemistry. 68: 65-106. PMID 15500859 DOI: 10.1016/S0065-3233(04)68003-X  0.658
2004 Himanen JP, Chumley MJ, Lackmann M, Li C, Barton WA, Jeffrey PD, Vearing C, Geleick D, Feldheim DA, Boyd AW, Henkemeyer M, Nikolov DB. Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling. Nature Neuroscience. 7: 501-9. PMID 15107857 DOI: 10.1038/Nn1237  0.627
2004 Thorson JS, Barton WA, Hoffmeister D, Albermann C, Nikolov DB. Structure-based enzyme engineering and its impact on in vitro glycorandomization. Chembiochem : a European Journal of Chemical Biology. 5: 16-25. PMID 14695508 DOI: 10.1002/Cbic.200300620  0.6
2003 Lesniak J, Barton WA, Nikolov DB. Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC. Protein Science : a Publication of the Protein Society. 12: 2838-43. PMID 14627744 DOI: 10.1110/Ps.03375603  0.735
2003 Antipenko A, Himanen JP, van Leyen K, Nardi-Dei V, Lesniak J, Barton WA, Rajashankar KR, Lu M, Hoemme C, Püschel AW, Nikolov DB. Structure of the semaphorin-3A receptor binding module. Neuron. 39: 589-98. PMID 12925274 DOI: 10.1016/S0896-6273(03)00502-6  0.747
2003 Barton WA, Liu BP, Tzvetkova D, Jeffrey PD, Fournier AE, Sah D, Cate R, Strittmatter SM, Nikolov DB. Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. The Embo Journal. 22: 3291-302. PMID 12839991 DOI: 10.1093/Emboj/Cdg325  0.656
2003 Albermann C, Soriano A, Jiang J, Vollmer H, Biggins JB, Barton WA, Lesniak J, Nikolov DB, Thorson JS. Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization. Organic Letters. 5: 933-6. PMID 12633109 DOI: 10.1021/Ol0341086  0.707
2002 Lesniak J, Barton WA, Nikolov DB. Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr. The Embo Journal. 21: 6649-59. PMID 12485986 DOI: 10.1093/Emboj/Cdf670  0.738
2002 Barton WA, Biggins JB, Jiang J, Thorson JS, Nikolov DB. Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proceedings of the National Academy of Sciences of the United States of America. 99: 13397-402. PMID 12374866 DOI: 10.1073/Pnas.192468299  0.581
2001 Barton WA, Lesniak J, Biggins JB, Jeffrey PD, Jiang J, Rajashankar KR, Thorson JS, Nikolov DB. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nature Structural Biology. 8: 545-51. PMID 11373625 DOI: 10.1038/88618  0.73
2001 Garrett S, Barton WA, Knights R, Jin P, Morgan DO, Fisher RP. Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop. Molecular and Cellular Biology. 21: 88-99. PMID 11113184 DOI: 10.1128/Mcb.21.1.88-99.2001  0.305
1999 Lee KM, Saiz JE, Barton WA, Fisher RP. Cdc2 activation in fission yeast depends on Mcs6 and Csk1, two partially redundant Cdk-activating kinases (CAKs) Current Biology. 9: 441-444. PMID 10226032 DOI: 10.1016/S0960-9822(99)80194-8  0.302
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