Year |
Citation |
Score |
2020 |
Maraschin JC, Sestile CC, Yabiku CT, Roncon CM, Fiaes GCdS, Graeff FG, Audi EA, Zangrossi H. Effects of the adjunctive treatment of antidepressants with opiorphin on a panic-like defensive response in rats. Behavioural Brain Research. 378: 112263. PMID 31568834 DOI: 10.1016/J.Bbr.2019.112263 |
0.388 |
|
2017 |
Sestile CC, Maraschin JC, Rangel MP, Santana RG, Zangrossi H, Graeff FG, Audi EA. B2-kinin receptors in the dorsal periaqueductal gray are implicated in the panicolytic-like effect of opiorphin. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 79: 493-498. PMID 28797641 DOI: 10.1016/J.Pnpbp.2017.08.003 |
0.412 |
|
2017 |
Shuhama R, Blanchard DC, Graeff FG, Del-Ben CM. What we imagine is what we do? A critical overview about mental imagery as a strategy to study human defensive responses. Behavioural Brain Research. 18-28. PMID 28716675 DOI: 10.1016/J.Bbr.2017.07.012 |
0.482 |
|
2017 |
Roncon CM, Yamashita PSM, Frias AT, Audi EA, Graeff FG, Coimbra NC, Zangrossi H. μ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses. Journal of Psychopharmacology (Oxford, England). 31: 715-721. PMID 28583050 DOI: 10.1177/0269881117693747 |
0.358 |
|
2017 |
Sestile CC, Maraschin JC, Gama VS, Zangrossi H, Graeff FG, Audi EA. Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through μ-opioid and B2-kinin receptors Neuropharmacology. 123: 80-87. PMID 28554847 DOI: 10.1016/J.Neuropharm.2017.05.025 |
0.375 |
|
2017 |
Maraschin JC, Almeida CB, Rangel MP, Roncon CM, Sestile CC, Zangrossi H, Graeff FG, Audi EA. Participation of dorsal periaqueductal gray 5-HT1A receptors in the panicolytic-like effect of the κ-opioid receptor antagonist Nor-BNI. Behavioural Brain Research. 327: 75-82. PMID 28347824 DOI: 10.1016/J.Bbr.2017.03.033 |
0.423 |
|
2017 |
Graeff FG. Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids. Neuroscience and Biobehavioral Reviews. PMID 28073587 DOI: 10.1016/J.Neubiorev.2016.10.013 |
0.348 |
|
2016 |
Shuhama R, Rondinoni C, de Araujo DB, de Freitas Caetano G, Dos Santos AC, Graeff FG, Del-Ben CM. Behavioral and Neuroimaging Responses Induced by Mental Imagery of Threatening Scenarios. Behavioural Brain Research. PMID 27452804 DOI: 10.1016/J.Bbr.2016.06.059 |
0.338 |
|
2015 |
Maraschin JC, Rangel MP, Bonfim AJ, Kitayama M, Graeff FG, Zangrossi H, Audi EA. Opiorphin causes a panicolytic-like effect in rat panic models mediated by μ-opioid receptors in the dorsal periaqueductal gray. Neuropharmacology. 101: 264-270. PMID 26363194 DOI: 10.1016/J.Neuropharm.2015.09.008 |
0.385 |
|
2015 |
Graeff FG, Sant'Ana AB, Vilela-Costa HH, Zangrossi H. New Findings on the Neurotransmitter Modulation of Defense in the Dorsal Periaqueductal Gray. Cns & Neurological Disorders Drug Targets. 14: 988-95. PMID 26350338 DOI: 10.2174/1871527314666150909114558 |
0.422 |
|
2015 |
Roncon CM, Almada RC, Maraschin JC, Audi EA, Zangrossi H, Graeff FG, Coimbra NC. Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter μ-opioid receptors. Neuropharmacology. 99: 620-626. PMID 26320545 DOI: 10.1016/J.Neuropharm.2015.08.037 |
0.379 |
|
2014 |
Rangel MP, Zangrossi H, Roncon CM, Graeff FG, Audi EA. Interaction between μ-opioid and 5-HT1A receptors in the regulation of panic-related defensive responses in the rat dorsal periaqueductal grey. Journal of Psychopharmacology (Oxford, England). 28: 1155-60. PMID 25315826 DOI: 10.1177/0269881114554274 |
0.396 |
|
2014 |
Garcia-Leal C, Graeff FG, Del-Ben CM. Experimental public speaking: contributions to the understanding of the serotonergic modulation of fear. Neuroscience and Biobehavioral Reviews. 46: 407-17. PMID 25277282 DOI: 10.1016/J.Neubiorev.2014.09.011 |
0.371 |
|
2014 |
Reis FM, Pestana-Oliveira N, Leite CM, Lima FB, Brandão ML, Graeff FG, Del-Ben CM, Anselmo-Franci JA. Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats. Psychoneuroendocrinology. 49: 130-40. PMID 25080405 DOI: 10.1016/J.Psyneuen.2014.06.019 |
0.358 |
|
2014 |
Canteras NS, Graeff FG. Executive and modulatory neural circuits of defensive reactions: implications for panic disorder. Neuroscience and Biobehavioral Reviews. 46: 352-64. PMID 24709069 DOI: 10.1016/J.Neubiorev.2014.03.020 |
0.389 |
|
2014 |
Zangrossi H, Graeff FG. Serotonin in anxiety and panic: contributions of the elevated T-maze. Neuroscience and Biobehavioral Reviews. 46: 397-406. PMID 24657635 DOI: 10.1016/J.Neubiorev.2014.03.007 |
0.471 |
|
2014 |
Audi E, Rangel M, Zangrossi H, Graeff F. P.4.a.003 Interaction between μ-opiod and 5-HT1A receptors in the regulation of panic-related defensive responses in rats European Neuropsychopharmacology. 24: S578. DOI: 10.1016/S0924-977X(14)70926-5 |
0.329 |
|
2014 |
Roncon CM, Almada RC, Maraschin JC, Elias-Filho DH, Audi EA, Zangrossi H, Graeff FG, Coimbra NC. P.1.g.028 Involvement of μ opioid receptor in the fluoxetine antipanic effect on rats submitted to the elevated T maze test European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70339-6 |
0.31 |
|
2013 |
Andrade TG, Zangrossi H, Graeff FG. The median raphe nucleus in anxiety revisited. Journal of Psychopharmacology (Oxford, England). 27: 1107-15. PMID 23999409 DOI: 10.1177/0269881113499208 |
0.434 |
|
2013 |
Roncon CM, Biesdorf C, Coimbra NC, Audi EA, Zangrossi H, Graeff FG. Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and μ-receptors. Journal of Psychopharmacology (Oxford, England). 27: 1141-8. PMID 23598399 DOI: 10.1177/0269881113485144 |
0.401 |
|
2013 |
Moreira FA, Gobira PH, Viana TG, Vicente MA, Zangrossi H, Graeff FG. Modeling panic disorder in rodents. Cell and Tissue Research. 354: 119-25. PMID 23584609 DOI: 10.1007/S00441-013-1610-1 |
0.36 |
|
2013 |
de Rezende MG, Garcia-Leal C, Graeff FG, Del-Ben CM. The 5-HT1D/1B receptor agonist sumatriptan enhances fear of simulated speaking and reduces plasma levels of prolactin. Journal of Psychopharmacology (Oxford, England). 27: 1124-33. PMID 23325368 DOI: 10.1177/0269881112472560 |
0.422 |
|
2012 |
Graeff FG. New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 45: 366-75. PMID 22437485 DOI: 10.1590/S0100-879X2012007500036 |
0.388 |
|
2012 |
Roncon CM, Biesdorf C, Santana RG, Zangrossi H, Graeff FG, Audi EA. The panicolytic-like effect of fluoxetine in the elevated T-maze is mediated by serotonin-induced activation of endogenous opioids in the dorsal periaqueductal grey. Journal of Psychopharmacology (Oxford, England). 26: 525-31. PMID 22279131 DOI: 10.1177/0269881111434619 |
0.424 |
|
2012 |
de Oliveira DC, Zuardi AW, Graeff FG, Queiroz RH, Crippa JA. Anxiolytic-like effect of oxytocin in the simulated public speaking test. Journal of Psychopharmacology (Oxford, England). 26: 497-504. PMID 21555332 DOI: 10.1177/0269881111400642 |
0.304 |
|
2012 |
Del-Ben CM, Ferreira CA, Sanchez TA, Alves-Neto WC, Guapo VG, de Araujo DB, Graeff FG. Effects of diazepam on BOLD activation during the processing of aversive faces. Journal of Psychopharmacology (Oxford, England). 26: 443-51. PMID 21106607 DOI: 10.1177/0269881110389092 |
0.307 |
|
2011 |
Mesquita SC, Shuhama R, Osório FL, Crippa JA, Loureiro SR, Landeira-Fernandez J, Graeff FG, Del-Ben CM. The response of social anxiety disorder patients to threat scenarios differs from that of healthy controls. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 44: 1261-8. PMID 22011960 DOI: 10.1590/S0100-879X2011007500137 |
0.335 |
|
2011 |
Sela VR, Biesdorf C, Ramos DH, Zangrossi H, Graeff FG, Audi EA. Serotonin-1A receptors in the dorsal periaqueductal gray matter mediate the panicolytic-like effect of pindolol and paroxetine combination in the elevated T-maze. Neuroscience Letters. 495: 63-6. PMID 21421022 DOI: 10.1016/J.Neulet.2011.03.040 |
0.426 |
|
2011 |
Graeff FG. Defense-related emotions in humans Psychology and Neuroscience. 4: 183-189. DOI: 10.3922/J.Psns.2011.2.003 |
0.387 |
|
2010 |
Sela VR, Roncon CM, Zangrossi H, Graeff FG, Audi EA. Pindolol potentiates the panicolytic effect of paroxetine in the elevated T-maze. Life Sciences. 87: 445-50. PMID 20816996 DOI: 10.1016/J.Lfs.2010.08.009 |
0.396 |
|
2010 |
Graeff FG, Zangrossi H. The dual role of serotonin in defense and the mode of action of antidepressants on generalized anxiety and panic disorders. Central Nervous System Agents in Medicinal Chemistry. 10: 207-17. PMID 20528764 DOI: 10.2174/1871524911006030207 |
0.454 |
|
2010 |
Alves-Neto WC, Guapo VG, Graeff FG, Deakin JF, Del-Ben CM. Effect of escitalopram on the processing of emotional faces. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 43: 285-9. PMID 20209375 DOI: 10.1590/S0100-879X2010005000007 |
0.31 |
|
2010 |
dos Santos L, de Andrade TG, Graeff FG. Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus. Journal of Psychopharmacology (Oxford, England). 24: 725-31. PMID 19939879 DOI: 10.1177/0269881109106954 |
0.344 |
|
2010 |
Garcia-Leal C, Del-Ben CM, Leal FM, Graeff FG, Guimarães FS. Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation. Journal of Psychopharmacology (Oxford, England). 24: 683-94. PMID 19251828 DOI: 10.1177/0269881108101782 |
0.39 |
|
2010 |
Graeff FG, Junior HZ. The hypothalamic-pituitary-adrenal axis in anxiety and panic Psychology and Neuroscience. 3. DOI: 10.3922/J.Psns.2010.1.002 |
0.371 |
|
2010 |
Guimarães FS, Zangrossi H, Ben CMD, Graeff FG. Serotonin in panic and anxiety disorders Handbook of Behavioral Neuroscience. 21: 667-685. DOI: 10.1016/S1569-7339(10)70105-3 |
0.415 |
|
2009 |
Andrade TG, Avanzi V, Graeff FG. Effect of estradiol benzoate microinjection into the median raphe nucleus on contextual conditioning. Behavioural Brain Research. 204: 112-6. PMID 19482044 DOI: 10.1016/J.Bbr.2009.05.029 |
0.391 |
|
2009 |
Del-Ben CM, Graeff FG. Panic disorder: is the PAG involved? Neural Plasticity. 2009: 108135. PMID 19283082 DOI: 10.1155/2009/108135 |
0.3 |
|
2009 |
Garcia-Leal C, Del-Ben C, Leal F, Graeff F, Guimarães F. P02-229 Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation European Psychiatry. 24: S919. DOI: 10.1016/S0924-9338(09)71152-6 |
0.392 |
|
2008 |
Graeff FG, Del-Ben CM. Neurobiology of panic disorder: from animal models to brain neuroimaging. Neuroscience and Biobehavioral Reviews. 32: 1326-35. PMID 18573531 DOI: 10.1016/J.Neubiorev.2008.05.017 |
0.368 |
|
2008 |
Del-Ben CM, Ferreira CA, Alves-Neto WC, Graeff FG. Serotonergic modulation of face-emotion recognition. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 41: 263-9. PMID 18392448 DOI: 10.1590/S0100-879X2008000400002 |
0.36 |
|
2008 |
Pinheiro SN, Del-Ben CM, Zangrossi H, Graeff FG. Anxiolytic and panicolytic effects of escitalopram in the elevated T-maze. Journal of Psychopharmacology (Oxford, England). 22: 132-7. PMID 18208911 DOI: 10.1177/0269881107079866 |
0.385 |
|
2008 |
Guimarães FS, Carobrez AP, Graeff FG. Chapter 4.3 Modulation of anxiety behaviors by 5-HT-interacting drugs Handbook of Behavioral Neuroscience. 17: 241-268. DOI: 10.1016/S1569-7339(07)00012-4 |
0.42 |
|
2007 |
Graeff FG. [Anxiety, panic and the hypothalamic-pituitary-adrenal axis]. Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 29: S3-6. PMID 17546345 DOI: 10.1590/S1516-44462007000500002 |
0.357 |
|
2007 |
Shuhama R, Del-Ben CM, Loureiro SR, Graeff FG. Animal defense strategies and anxiety disorders. Anais Da Academia Brasileira De CiãªNcias. 79: 97-109. PMID 17401479 DOI: 10.1590/S0001-37652007000100012 |
0.347 |
|
2007 |
Pinheiro SH, Zangrossi H, Del-Ben CM, Graeff FG. Elevated mazes as animal models of anxiety: effects of serotonergic agents. Anais Da Academia Brasileira De CiãªNcias. 79: 71-85. PMID 17401477 DOI: 10.1590/S0001-37652007000100010 |
0.396 |
|
2005 |
Graeff FG, Garcia-Leal C, Del-Ben CM, Guimarães FS. Does the panic attack activate the hypothalamic-pituitary-adrenal axis? Anais Da Academia Brasileira De CiãªNcias. 77: 477-91. PMID 16127553 DOI: 10.1590/S0001-37652005000300009 |
0.347 |
|
2005 |
Parente AC, Garcia-Leal C, Del-Ben CM, Guimarães FS, Graeff FG. Subjective and neurovegetative changes in healthy volunteers and panic patients performing simulated public speaking. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 15: 663-71. PMID 15961294 DOI: 10.1016/J.Euroneuro.2005.05.002 |
0.322 |
|
2005 |
Andrade TG, Nakamuta JS, Avanzi V, Graeff FG. Anxiolytic effect of estradiol in the median raphe nucleus mediated by 5-HT1A receptors. Behavioural Brain Research. 163: 18-25. PMID 15951031 DOI: 10.1016/J.Bbr.2005.04.015 |
0.393 |
|
2005 |
Garcia-Leal C, Parente AC, Del-Ben CM, Guimarães FS, Moreira AC, Elias LL, Graeff FG. Anxiety and salivary cortisol in symptomatic and nonsymptomatic panic patients and healthy volunteers performing simulated public speaking. Psychiatry Research. 133: 239-52. PMID 15740999 DOI: 10.1016/J.Psychres.2004.04.010 |
0.333 |
|
2004 |
Graeff FG. Serotonin, the periaqueductal gray and panic. Neuroscience and Biobehavioral Reviews. 28: 239-59. PMID 15225969 DOI: 10.1016/J.Neubiorev.2003.12.004 |
0.452 |
|
2004 |
Andrade TG, Macedo CE, Zangrossi H, Graeff FG. Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze. Behavioural Brain Research. 153: 55-60. PMID 15219706 DOI: 10.1016/J.Bbr.2003.10.036 |
0.388 |
|
2003 |
Graeff FG. [Serotonin, periaqueductal gray matter and panic disorder]. Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 25: 42-5. PMID 14978586 DOI: 10.1590/S1516-44462003000600010 |
0.45 |
|
2003 |
Graeff FG, Parente A, Del-Ben CM, Guimarães FS. Pharmacology of human experimental anxiety. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 36: 421-32. PMID 12700819 DOI: 10.1590/S0100-879X2003000400003 |
0.388 |
|
2002 |
Graeff FG. On serotonin and experimental anxiety. Psychopharmacology. 163: 467-76. PMID 12373447 DOI: 10.1007/S00213-002-1112-4 |
0.464 |
|
2001 |
Graeff FG, Silva M, Del Ben CM, Zuardi AW, Hetem LA, Guimarães FS. Comparison between two models of experimental anxiety in healthy volunteers and panic disorder patients. Neuroscience and Biobehavioral Reviews. 25: 753-9. PMID 11801299 DOI: 10.1016/S0149-7634(01)00055-0 |
0.432 |
|
2001 |
Carobrez AP, Teixeira KV, Graeff FG. Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor. Neuroscience and Biobehavioral Reviews. 25: 697-709. PMID 11801295 DOI: 10.1016/S0149-7634(01)00059-8 |
0.323 |
|
2001 |
Zangrossi H, Viana MB, Zanoveli J, Bueno C, Nogueira RL, Graeff FG. Serotonergic regulation of inhibitory avoidance and one-way escape in the rat elevated T-maze. Neuroscience and Biobehavioral Reviews. 25: 637-45. PMID 11801289 DOI: 10.1016/S0149-7634(01)00047-1 |
0.449 |
|
2001 |
Vianna DM, Graeff FG, Brandão ML, Landeira-Fernandez J. Defensive freezing evoked by electrical stimulation of the periaqueductal gray: comparison between dorsolateral and ventrolateral regions. Neuroreport. 12: 4109-12. PMID 11742247 DOI: 10.1097/00001756-200112210-00049 |
0.317 |
|
2001 |
Del-Ben CM, Vilela JA, Hetem LA, Guimarães FS, Graeff FG, Zuardi AW. Do panic patients process unconditioned fear vs. conditioned anxiety differently than normal subjects? Psychiatry Research. 104: 227-37. PMID 11728612 DOI: 10.1016/S0165-1781(01)00312-2 |
0.339 |
|
2001 |
Silveira MC, Zangrossi H, de Barros Viana M, Silveira R, Graeff FG. Differential expression of Fos protein in the rat brain induced by performance of avoidance or escape in the elevated T-maze. Behavioural Brain Research. 126: 13-21. PMID 11704247 DOI: 10.1016/S0166-4328(01)00233-9 |
0.341 |
|
2001 |
Silva M, Hetem LA, Guimarães FS, Graeff FG. Opposite effects of nefazodone in two human models of anxiety. Psychopharmacology. 156: 454-60. PMID 11498723 DOI: 10.1007/S002130100752 |
0.425 |
|
2001 |
Vianna DM, Graeff FG, Landeira-Fernandez J, Brandão ML. Lesion of the ventral periaqueductal gray reduces conditioned fear but does not change freezing induced by stimulation of the dorsal periaqueductal gray. Learning & Memory (Cold Spring Harbor, N.Y.). 8: 164-9. PMID 11390636 DOI: 10.1101/Lm.36101 |
0.359 |
|
2001 |
Andreatini R, Blanchard C, Blanchard R, Brandão ML, Carobrez AP, Griebel G, Guimarães FS, Handley SL, Jenck F, Leite JR, Rodgers J, Schenberg LC, Da Cunha C, Graeff FG. The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 34: 145-54. PMID 11175489 DOI: 10.1590/S0100-879X2001000200001 |
0.554 |
|
2001 |
Graeff FG. Aspectos neuroquímicos: o papel da serotonina no TOC Revista Brasileira De Psiquiatria. 23: 35-37. DOI: 10.1590/S1516-44462001000600011 |
0.399 |
|
2001 |
Blanchard RJ, Blanchard DC, Graeff FG. Foreword Neuroscience and Biobehavioral Reviews. 25: 575-576. DOI: 10.1016/S0149-7634(01)00061-6 |
0.535 |
|
2000 |
Salgado JV, Hetem LA, Vidal M, Graeff FG, Danion JM, Sandner G. Reduction of latent inhibition by D-amphetamine in a conditioned suppression paradigm in humans. Behavioural Brain Research. 117: 61-7. PMID 11099758 DOI: 10.1016/S0166-4328(00)00279-5 |
0.313 |
|
2000 |
Nunes-de-Souza RL, Canto-de-Souza A, da-Costa M, Fornari RV, Graeff FG, Pelá IR. Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam. Psychopharmacology. 150: 300-10. PMID 10923758 DOI: 10.1007/S002130000428 |
0.46 |
|
2000 |
Teixeira RC, Zangrossi H, Graeff FG. Behavioral effects of acute and chronic imipramine in the elevated T-maze model of anxiety. Pharmacology, Biochemistry, and Behavior. 65: 571-6. PMID 10764908 DOI: 10.1016/S0091-3057(99)00261-0 |
0.379 |
|
1999 |
Zangrossi H, Viana MB, Graeff FG. Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino)tetralin in the elevated T-maze. European Journal of Pharmacology. 369: 267-70. PMID 10225362 DOI: 10.1016/S0014-2999(99)00075-8 |
0.404 |
|
1999 |
De Oliveira Mora P, Fouquet N, Oberling P, Gobaille S, Graeff FG, Sandner G. A neurotoxic lesion of serotonergic neurones using 5,7-dihydroxytryptamine does not disrupt latent inhibition in paradigms sensitive to low doses of amphetamine. Behavioural Brain Research. 100: 167-75. PMID 10212064 DOI: 10.1016/S0166-4328(98)00128-4 |
0.356 |
|
1998 |
Graeff FG, Netto CF, Zangrossi H. The elevated T-maze as an experimental model of anxiety. Neuroscience and Biobehavioral Reviews. 23: 237-46. PMID 9884116 DOI: 10.1016/S0149-7634(98)00024-4 |
0.471 |
|
1998 |
Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG. Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. European Journal of Pharmacology. 345: 253-6. PMID 9592023 DOI: 10.1016/S0014-2999(98)00018-1 |
0.323 |
|
1997 |
Graeff FG, Viana MB, Mora PO. Dual role of 5-HT in defense and anxiety. Neuroscience and Biobehavioral Reviews. 21: 791-9. PMID 9415904 DOI: 10.1016/S0149-7634(96)00059-0 |
0.442 |
|
1997 |
Mora PO, Netto CF, Graeff FG. Role of 5-HT2A and 5-HT2C receptor subtypes in the two types of fear generated by the elevated T-maze. Pharmacology, Biochemistry, and Behavior. 58: 1051-7. PMID 9408213 DOI: 10.1016/S0091-3057(97)00057-9 |
0.435 |
|
1997 |
Zangrossi H, Graeff FG. Behavioral validation of the elevated T-maze, a new animal model of anxiety. Brain Research Bulletin. 44: 1-5. PMID 9288825 DOI: 10.1016/S0361-9230(96)00381-4 |
0.361 |
|
1997 |
Viana MB, Graeff FG, Löschmann PA. Kainate microinjection into the dorsal raphe nucleus induces 5-HT release in the amygdala and periaqueductal gray. Pharmacology, Biochemistry, and Behavior. 58: 167-72. PMID 9264086 DOI: 10.1016/S0091-3057(96)00451-0 |
0.452 |
|
1997 |
Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG. High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors. Pharmacology, Biochemistry, and Behavior. 56: 481-6. PMID 9077586 DOI: 10.1016/S0091-3057(96)00246-8 |
0.308 |
|
1996 |
Hetem LA, de Souza CJ, Guimarães ES, Zuardi AW, Graeff FG. Effect of d-fenfluramine on human experimental anxiety. Psychopharmacology. 127: 276-82. PMID 8912406 DOI: 10.1007/S002130050086 |
0.449 |
|
1996 |
Graeff FG, Viana MB, Mora PO. Opposed regulation by dorsal raphe nucleus 5-HT pathways of two types of fear in the elevated T-maze. Pharmacology, Biochemistry, and Behavior. 53: 171-7. PMID 8848447 DOI: 10.1016/0091-3057(95)02012-8 |
0.456 |
|
1996 |
Gargiulo PA, Viana MB, Graeff FG, Silva MA, Tomaz C. Effects of anxiety and memory of systemic and intra-amygdala injection of 5-HT3 receptor antagonist BRL 46470A. Neuropsychobiology. 33: 189-95. PMID 8840342 DOI: 10.1159/000119276 |
0.429 |
|
1996 |
Scorza MC, Reyes-Parada M, Silveira R, Viola H, Medina JH, Viana MB, Zangrossi H, Graeff FG. Behavioral effects of the putative anxiolytic (+/-)-1-(2,5-dimethoxy-4-ethylthiophenyl)-2-aminopropane (ALEPH-2) in rats and mice. Pharmacology, Biochemistry, and Behavior. 54: 355-61. PMID 8743595 DOI: 10.1016/0091-3057(95)02149-3 |
0.353 |
|
1996 |
Graeff FG, Guimarães FS, De Andrade TG, Deakin JF. Role of 5-HT in stress, anxiety, and depression. Pharmacology, Biochemistry, and Behavior. 54: 129-41. PMID 8728550 DOI: 10.1016/0091-3057(95)02135-3 |
0.45 |
|
1995 |
Silveira MC, Sandner G, Di Scala G, Graeff FG. c-fos immunoreactivity in the brain following electrical or chemical stimulation of the medial hypothalamus of freely moving rats. Brain Research. 674: 265-74. PMID 7796106 DOI: 10.1016/0006-8993(94)01451-M |
0.309 |
|
1995 |
Nogueira RL, Graeff FG. Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion. Pharmacology, Biochemistry, and Behavior. 52: 1-6. PMID 7501649 DOI: 10.1016/0091-3057(94)00402-5 |
0.414 |
|
1995 |
Graeff FG, de Barros Viana M, de Oliveira Mora P, Guimar??es FS, Hetem LA. Dual role of 5-HT in experimental anxiety Behavioural Pharmacology. 6: 146. DOI: 10.1097/00008877-199505001-00174 |
0.382 |
|
1995 |
Connell J, Graeff F, Guimareas F, Hellewell JS, Hettem LA, Deakin JF. 5HT2 receptors and anxiety Behavioural Pharmacology. 6: 35. DOI: 10.1097/00008877-199505001-00039 |
0.391 |
|
1994 |
Graeff FG. Neuroanatomy and neurotransmitter regulation of defensive behaviors and related emotions in mammals. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 27: 811-29. PMID 7916235 |
0.307 |
|
1994 |
Matheus MG, Nogueira RL, Carobrez AP, Graeff FG, Guimarães FS. Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey. Psychopharmacology. 113: 565-9. PMID 7862877 DOI: 10.1007/Bf02245241 |
0.399 |
|
1994 |
Viana MB, Tomaz C, Graeff FG. The elevated T-maze: a new animal model of anxiety and memory. Pharmacology, Biochemistry, and Behavior. 49: 549-54. PMID 7862706 DOI: 10.1016/0091-3057(94)90067-1 |
0.357 |
|
1994 |
Zangrossi Júnior H, Graeff FG. Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 27: 2453-6. PMID 7640637 |
0.332 |
|
1993 |
Zuardi AW, Cosme RA, Graeff FG, Guimarães FS. Effects of ipsapirone and cannabidiol on human experimental anxiety. Journal of Psychopharmacology (Oxford, England). 7: 82-8. PMID 22290374 DOI: 10.1177/026988119300700112 |
0.364 |
|
1993 |
Silveira MC, Sandner G, Graeff FG. Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze. Behavioural Brain Research. 56: 115-8. PMID 8397853 DOI: 10.1016/0166-4328(93)90028-O |
0.327 |
|
1993 |
de Souza Silva M, Guimarães FS, Graeff FG, Tomaz C. Absence of amnestic effect of an anxiolytic 5-HT3 antagonist (BRL 46470A) injected into basolateral amygdala, as opposed to diazepam. Behavioural Brain Research. 59: 141-5. PMID 8155281 DOI: 10.1016/0166-4328(93)90160-R |
0.37 |
|
1993 |
Tomaz C, Dickinson-Anson H, McGaugh JL, Souza-Silva MA, Viana MB, Graeff FG. Localization in the amygdala of the amnestic action of diazepam on emotional memory. Behavioural Brain Research. 58: 99-105. PMID 8136053 DOI: 10.1016/0166-4328(93)90094-7 |
0.338 |
|
1993 |
Graeff FG, Silveira MC, Nogueira RL, Audi EA, Oliveira RM. Role of the amygdala and periaqueductal gray in anxiety and panic. Behavioural Brain Research. 58: 123-31. PMID 8136040 DOI: 10.1016/0166-4328(93)90097-A |
0.452 |
|
1993 |
Graeff FG. Role of 5-HT in defensive behavior and anxiety. Reviews in the Neurosciences. 4: 181-211. PMID 7952387 DOI: 10.1515/Revneuro.1993.4.2.181 |
0.397 |
|
1993 |
Russo AS, Guimarães FS, De Aguiar JC, Graeff FG. Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety. Psychopharmacology. 110: 198-202. PMID 7870885 DOI: 10.1007/Bf02246973 |
0.435 |
|
1992 |
Silveira MC, Graeff FG. Defense reaction elicited by microinjection of kainic acid into the medial hypothalamus of the rat: antagonism by a GABAA receptor agonist. Behavioral and Neural Biology. 57: 226-32. PMID 1319704 DOI: 10.1016/0163-1047(92)90192-7 |
0.316 |
|
1991 |
Deakin JF, Graeff FG. 5-HT and mechanisms of defence. Author's response. Journal of Psychopharmacology (Oxford, England). 5: 339-41. PMID 22282838 DOI: 10.1177/026988119100500423 |
0.332 |
|
1991 |
Deakin JF, Graeff FG. 5-HT and mechanisms of defence. Journal of Psychopharmacology (Oxford, England). 5: 305-15. PMID 22282829 DOI: 10.1177/026988119100500414 |
0.335 |
|
1991 |
Audi EA, de Oliveira RM, Graeff FG. Microinjection of propranolol into the dorsal periaqueductal gray causes an anxiolytic effect in the elevated plus-maze antagonized by ritanserin. Psychopharmacology. 105: 553-7. PMID 1685253 DOI: 10.1007/Bf02244379 |
0.409 |
|
1991 |
Brandão ML, Lopez-Garcia JA, Graeff FG, Roberts MH. Electrophysiological evidence for excitatory 5-HT2 and depressant 5-HT1A receptors on neurones of the rat midbrain tectum. Brain Research. 556: 259-66. PMID 1682008 DOI: 10.1016/0006-8993(91)90313-K |
0.39 |
|
1991 |
Deakin JFW, Graeff FG, Rodgers RJ, Broekkamp CL, Handley SL, McBlane JW, Everitt B, Robbins T, Shepherd JK, Blanchard DC, De Padua Carobrez A, Blanchard RJ, Wetzler S, Asnis GM, Van Praag HM, et al. Critique: 5-HT and mechanisms of defence Journal of Psychopharmacology. 5: 305-341. |
0.57 |
|
1990 |
Graeff FG, Audi EA, Almeida SS, Graeff EO, Hunziker MH. Behavioral effects of 5-HT receptor ligands in the aversive brain stimulation, elevated plus-maze and learned helplessness tests. Neuroscience and Biobehavioral Reviews. 14: 501-6. PMID 2287488 DOI: 10.1016/S0149-7634(05)80074-0 |
0.425 |
|
1990 |
Almeida SS, de Oliveira LM, Graeff FG. Decreased reactivity to anxiolytics caused by early protein malnutrition in rats. Pharmacology, Biochemistry, and Behavior. 36: 997-1000. PMID 1977181 DOI: 10.1016/0091-3057(90)90113-V |
0.317 |
|
1990 |
Guimarães FS, Chiaretti TM, Graeff FG, Zuardi AW. Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology. 100: 558-9. PMID 1969666 DOI: 10.1007/Bf02244012 |
0.349 |
|
1989 |
Audi EA, de-Oliveira CE, Graeff FG. Serotonergic mediation of the anxiolytic effect of intracerebrally injected propranolol measured in the elevated plus-maze. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 22: 699-701. PMID 2515907 |
0.341 |
|
1988 |
Audi EA, de Aguiar JC, Graeff FG. Mediation by serotonin of the antiaversive effect of zimelidine and propranolol injected into the dorsal midbrain central grey. Journal of Psychopharmacology (Oxford, England). 2: 26-32. PMID 22159666 DOI: 10.1177/026988118800200105 |
0.433 |
|
1987 |
Guimarães FS, Zuardi AW, Graeff FG. Effect of chlorimipramine and maprotiline on experimental anxiety in humans. Journal of Psychopharmacology (Oxford, England). 1: 184-92. PMID 22158980 DOI: 10.1177/026988118700100305 |
0.42 |
|
1987 |
Audi EA, Graeff FG. GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA. European Journal of Pharmacology. 135: 225-9. PMID 3034627 DOI: 10.1016/0014-2999(87)90615-7 |
0.349 |
|
1986 |
Graeff FG, Brandão ML, Audi EA, Schütz MT. Modulation of the brain aversive system by GABAergic and serotonergic mechanisms. Behavioural Brain Research. 22: 173-80. PMID 3024664 DOI: 10.1016/0166-4328(85)90120-2 |
0.305 |
|
1985 |
Graeff FG, Zuardi AW, Giglio JS, Lima Filho EC, Karniol IG. Effect of metergoline on human anxiety. Psychopharmacology. 86: 334-8. PMID 3929304 DOI: 10.1007/Bf00432224 |
0.412 |
|
1985 |
Schütz MT, de Aguiar JC, Graeff FG. Anti-aversive role of serotonin in the dorsal periaqueductal grey matter. Psychopharmacology. 85: 340-5. PMID 3159032 DOI: 10.1007/Bf00428199 |
0.403 |
|
1984 |
Audi EA, Graeff FG. Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action. European Journal of Pharmacology. 103: 279-85. PMID 6092103 DOI: 10.1016/0014-2999(84)90488-6 |
0.36 |
|
1984 |
Graeff FG. The anti-aversive action of minor tranquillizers Trends in Pharmacological Sciences. 5: 230-233. DOI: 10.1016/0165-6147(84)90428-0 |
0.363 |
|
1983 |
Carobrez AP, Schenberg LC, Graeff FG. Neuroeffector mechanisms of the defense reaction in the rat. Physiology & Behavior. 31: 439-44. PMID 6657764 DOI: 10.1016/0031-9384(83)90063-X |
0.352 |
|
1983 |
Schenberg LC, De Aguiar JC, Graeff FG. GABA modulation of the defense reaction induced by brain electrical stimulation. Physiology & Behavior. 31: 429-37. PMID 6318241 DOI: 10.1016/0031-9384(83)90062-8 |
0.366 |
|
1981 |
Morato de Carvalho S, de Aguiar JC, Graeff FG. Effect of minor tranquilizers, tryptamine antagonists and amphetamine on behavior punished by brain stimulation. Pharmacology, Biochemistry, and Behavior. 15: 351-6. PMID 6117081 DOI: 10.1016/0091-3057(81)90261-6 |
0.382 |
|
1980 |
Brandão ML, Fontes JC, Graeff FG. Facilitatory effect of ketamine on punished behavior. Pharmacology, Biochemistry, and Behavior. 13: 1-4. PMID 7403212 DOI: 10.1016/0091-3057(80)90110-0 |
0.323 |
|
1980 |
Graeff FG, Rawlins JN. Dorsal periaqueductal gray punishment, septal lesions and the mode of action of minor tranquilizers. Pharmacology, Biochemistry, and Behavior. 12: 41-5. PMID 7367461 DOI: 10.1016/0091-3057(80)90413-X |
0.61 |
|
1980 |
Graeff FG, Quintero S, Gray JA. Median raphe stimulation, hippocampal theta rhythm and threat-induced behavioral inhibition. Physiology & Behavior. 25: 253-61. PMID 6447883 DOI: 10.1016/0031-9384(80)90213-9 |
0.504 |
|
1978 |
Schenberg LC, Graeff FG. Role of the periaqueductal gray substance in the antianxiety action of benzodiazepines. Pharmacology, Biochemistry, and Behavior. 9: 287-95. PMID 568804 DOI: 10.1016/0091-3057(78)90287-3 |
0.369 |
|
1976 |
Corrêa FM, Graeff FG. On the mechanism of the hypertensive action of intraseptal bradykinin in the rat. Neuropharmacology. 15: 713-7. PMID 1004694 DOI: 10.1016/0028-3908(76)90042-3 |
0.304 |
|
1975 |
Graeff FG, De Oliveira L. Influence of response topography on the effect of apomorphine and amphetamine on operant behavior of pigeons. Psychopharmacologia. 41: 127-32. PMID 1171486 DOI: 10.1007/Bf00421069 |
0.314 |
|
1974 |
Peres VL, Gentil CG, Graeff FG, Covian MR. Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat. Pharmacology, Biochemistry, and Behavior. 2: 597-602. PMID 4372640 DOI: 10.1016/0091-3057(74)90026-4 |
0.301 |
|
1973 |
Graeff FG, Gentil CG, Peres VL, Covian MR. Lever-pressing behavior caused by intraseptal angiotensin II in water satiated rats. Pharmacology, Biochemistry, and Behavior. 1: 357-9. PMID 4359806 DOI: 10.1016/0091-3057(73)90129-9 |
0.306 |
|
1971 |
Ribeiro SA, Corrado AP, Graeff FG. Antinociceptive action of intraventricular bradykinin. Neuropharmacology. 10: 725-31. PMID 5316055 DOI: 10.1016/0028-3908(71)90087-6 |
0.305 |
|
1970 |
Graeff FG, Schoenfeld RI. Tryptaminergic mechanisms in punished and nonpunished behavior. The Journal of Pharmacology and Experimental Therapeutics. 173: 277-83. PMID 5434014 |
0.6 |
|
1969 |
Graeff FG, Pelá IR, Roch e Silva M. Behavioural and somatic effects of bradykinin injected into the cerebral ventricles of unanaesthetized rabbits. British Journal of Pharmacology. 37: 723-32. PMID 5388583 DOI: 10.1016/S0031-6989(69)80077-9 |
0.322 |
|
1965 |
GRAEFF FG, LEME JG, ROCHAESILVA M. ROLE PLAYED BY CATECHOL AND INDOLAMINES IN THE CENTRAL ACTIONS OF RESERPINE AFTER MONO-AMINOXIDASE INHIBITION. International Journal of Neuropharmacology. 4: 17-26. PMID 14346146 DOI: 10.1016/0028-3908(65)90043-2 |
0.349 |
|
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