David A. Brown - Publications

Affiliations: 
Neuroscience, Physiology & Pharmacology University College, University of London, London, England, United Kingdom 
Area:
Regulation of ion channels that control neural excitability
Website:
http://www.ucl.ac.uk/npp/people/brown-david

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Year Citation  Score
2020 Brown DA. Neurons, Receptors, and Channels. Annual Review of Pharmacology and Toxicology. 60: 9-30. PMID 31914894 DOI: 10.1146/Annurev-Pharmtox-010919-023755  0.439
2019 Robbins J, Caulfield MP, Higashida H, Brown DA. Genotypic m3-Muscarinic Receptors Preferentially Inhibit M-currents in DNA-transfected NG108-15 Neuroblastoma x Glioma Hybrid Cells. The European Journal of Neuroscience. 3: 820-824. PMID 12106468 DOI: 10.1111/J.1460-9568.1991.Tb01678.X  0.378
2018 Telezhkin V, Straccia M, Yarova P, Pardo M, Yung S, Vinh NN, Hancock JM, Barriga GG, Brown DA, Rosser AE, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Archiv : European Journal of Physiology. PMID 29797067 DOI: 10.1007/S00424-018-2155-7  0.366
2017 Brown DA. Regulation of neural ion channels by muscarinic receptors. Neuropharmacology. PMID 29154951 DOI: 10.1016/J.Neuropharm.2017.11.024  0.382
2017 Brown DA. Norman Bowery's discoveries about extrasynaptic and asynaptic GABA systems and their significance. Neuropharmacology. PMID 29128306 DOI: 10.1016/J.Neuropharm.2017.11.006  0.386
2015 Reilly JM, Dharmalingam B, Marsh SJ, Thompson V, Goebel A, Brown DA. Effects of serum immunoglobulins from patients with complex regional pain syndrome (CRPS) on depolarisation-induced calcium transients in isolated dorsal root ganglion (DRG) neurons. Experimental Neurology. PMID 26708558 DOI: 10.1016/J.Expneurol.2015.12.009  0.338
2015 Martinello K, Huang Z, Lujan R, Tran B, Watanabe M, Cooper EC, Brown DA, Shah MM. Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells. Neuron. 85: 346-63. PMID 25578363 DOI: 10.1016/J.Neuron.2014.12.030  0.393
2014 Telezhkin V, Thompson BA, Pardo M, Garcia-Diaz Barriga G, Brown DA, Canals JM, Allen ND, Kemp PJ. Kv7.2/7.3 Channels are Enhanced During Striatal Development and Promote Neuronal Functional Maturation of iPS Cell-Derived Neurons Biophysical Journal. 106: 142a. DOI: 10.1016/J.Bpj.2013.11.823  0.388
2013 Robbins J, Passmore GM, Abogadie FC, Reilly JM, Brown DA. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents. Plos One. 8: e71809. PMID 23977150 DOI: 10.1371/Journal.Pone.0071809  0.397
2013 Reilly JM, Telezhkin V, Passmore GM, Marsh SJ, Brown DA. Kv7/M-type potassium channels in rat skin keratinocytes. Pflã¼Gers Archiv : European Journal of Physiology. 465: 1371-81. PMID 23592175 DOI: 10.1007/S00424-013-1276-2  0.384
2013 Telezhkin V, Thomas AM, Harmer SC, Tinker A, Brown DA. A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)Pâ‚‚. Pflã¼Gers Archiv : European Journal of Physiology. 465: 945-53. PMID 23291709 DOI: 10.1007/S00424-012-1199-3  0.355
2013 Filippov AK, Brown DA. A mechanism for nerve cell excitation by norepinephrine via α-1 adrenoceptors: inhibition of potassium M-current. Cellular and Molecular Neurobiology. 33: 1-4. PMID 22872321 DOI: 10.1007/S10571-012-9870-Y  0.468
2013 Brown DA. The other (muscarinic) acetylcholine receptors in sympathetic ganglia: Actions and mechanisms Neurophysiology. 45: 60-66. DOI: 10.1007/S11062-013-9337-X  0.461
2012 Telezhkin V, Brown DA, Gibb AJ. Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2. The Journal of General Physiology. 140: 41-53. PMID 22689829 DOI: 10.1085/Jgp.201210796  0.36
2012 Passmore GM, Reilly JM, Thakur M, Keasberry VN, Marsh SJ, Dickenson AH, Brown DA. Functional significance of M-type potassium channels in nociceptive cutaneous sensory endings. Frontiers in Molecular Neuroscience. 5: 63. PMID 22593734 DOI: 10.3389/Fnmol.2012.00063  0.374
2012 Telezhkin V, Reilly JM, Thomas AM, Tinker A, Brown DA. Structural requirements of membrane phospholipids for M-type potassium channel activation and binding. The Journal of Biological Chemistry. 287: 10001-12. PMID 22303005 DOI: 10.1074/Jbc.M111.322552  0.358
2012 Telezhkin V, Gibb AJ, Brown DA. Activation of M-Type Potassium Channels by Different Membrane Phospholipids and Analogs Biophysical Journal. 102: 411a. DOI: 10.1016/J.Bpj.2011.11.2249  0.329
2011 Shah MM, Migliore M, Brown DA. Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons. The Journal of Physiology. 589: 6029-38. PMID 22041186 DOI: 10.1113/Jphysiol.2011.220913  0.401
2010 Filippov AK, Simon J, Barnard EA, Brown DA. The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11068-72. PMID 20720114 DOI: 10.1523/Jneurosci.2597-10.2010  0.343
2010 Brown DA. Muscarinic acetylcholine receptors (mAChRs) in the nervous system: some functions and mechanisms. Journal of Molecular Neuroscience : Mn. 41: 340-6. PMID 20446119 DOI: 10.1007/S12031-010-9377-2  0.436
2009 Brown DA, Passmore GM. Neural KCNQ (Kv7) channels. British Journal of Pharmacology. 156: 1185-95. PMID 19298256 DOI: 10.1111/J.1476-5381.2009.00111.X  0.445
2009 Nakamoto T, Brown DA, Catalán MA, Gonzalez-Begne M, Romanenko VG, Melvin JE. Purinergic P2X7 receptors mediate ATP-induced saliva secretion by the mouse submandibular gland. The Journal of Biological Chemistry. 284: 4815-22. PMID 19097994 DOI: 10.1074/Jbc.M808597200  0.344
2008 Shah MM, Migliore M, Valencia I, Cooper EC, Brown DA. Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 7869-74. PMID 18515424 DOI: 10.1073/Pnas.0802805105  0.361
2008 Lang PM, Fleckenstein J, Passmore GM, Brown DA, Grafe P. Retigabine reduces the excitability of unmyelinated peripheral human axons. Neuropharmacology. 54: 1271-8. PMID 18474382 DOI: 10.1016/J.Neuropharm.2008.04.006  0.32
2008 Brown DA. Kv7 (KCNQ) potassium channels that are mutated in human diseases. The Journal of Physiology. 586: 1781-3. PMID 18381340 DOI: 10.1113/Jphysiol.2008.153007  0.384
2008 Brown DA, Sihra TS. Presynaptic signaling by heterotrimeric G-proteins. Handbook of Experimental Pharmacology. 207-60. PMID 18064416 DOI: 10.1007/978-3-540-74805-2_8  0.329
2007 Hughes S, Marsh SJ, Tinker A, Brown DA. PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. Pflã¼Gers Archiv : European Journal of Physiology. 455: 115-24. PMID 17447081 DOI: 10.1007/S00424-007-0259-6  0.423
2007 Brown DA, Hughes SA, Marsh SJ, Tinker A. Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. The Journal of Physiology. 582: 917-25. PMID 17395626 DOI: 10.1113/Jphysiol.2007.132498  0.371
2007 Brown DA, Lancaster B, Shah MM. Hippocalcin: a new solution to an old puzzle. Neuron. 53: 467-8. PMID 17296544 DOI: 10.1016/J.Neuron.2007.01.026  0.326
2007 Maslov VY, Brown DA. Changes in the intracellular calcium concentration upon activation of rat superior cervical ganglion neurons Neurophysiology. 39: 350-352. DOI: 10.1007/S11062-007-0054-1  0.34
2007 Brown DA. The Skok legacy and beyond: Molecular mechanisms of slow synaptic excitation in sympathetic ganglia Neurophysiology. 39: 243-247. DOI: 10.1007/S11062-007-0033-6  0.376
2006 Filippov AK, Choi RC, Simon J, Barnard EA, Brown DA. Activation of P2Y1 nucleotide receptors induces inhibition of the M-type K+ current in rat hippocampal pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9340-8. PMID 16957090 DOI: 10.1523/Jneurosci.2635-06.2006  0.408
2006 Robbins J, Marsh SJ, Brown DA. Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7950-61. PMID 16870740 DOI: 10.1523/Jneurosci.2138-06.2006  0.448
2006 Street M, Marsh SJ, Stabach PR, Morrow JS, Brown DA, Buckley NJ. Stimulation of Galphaq-coupled M1 muscarinic receptor causes reversible spectrin redistribution mediated by PLC, PKC and ROCK. Journal of Cell Science. 119: 1528-36. PMID 16551696 DOI: 10.1242/Jcs.02872  0.361
2005 Delmas P, Brown DA. Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nature Reviews. Neuroscience. 6: 850-62. PMID 16261179 DOI: 10.1038/Nrn1785  0.373
2005 Winks JS, Hughes S, Filippov AK, Tatulian L, Abogadie FC, Brown DA, Marsh SJ. Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3400-13. PMID 15800195 DOI: 10.1523/Jneurosci.3231-04.2005  0.369
2004 Filippov AK, Fernández-Fernández JM, Marsh SJ, Simon J, Barnard EA, Brown DA. Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors. Molecular Pharmacology. 66: 468-77. PMID 15322238 DOI: 10.1124/Mol.66.3  0.445
2004 Delmas P, Crest M, Brown DA. Functional organization of PLC signaling microdomains in neurons. Trends in Neurosciences. 27: 41-7. PMID 14698609 DOI: 10.1016/J.Tins.2003.10.013  0.3
2004 Allen TG, Brown DA. Modulation of the excitability of cholinergic basal forebrain neurones by KATP channels. The Journal of Physiology. 554: 353-70. PMID 14578474 DOI: 10.1113/Jphysiol.2003.055889  0.397
2003 Passmore GM, Selyanko AA, Mistry M, Al-Qatari M, Marsh SJ, Matthews EA, Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA. KCNQ/M currents in sensory neurons: significance for pain therapy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7227-36. PMID 12904483 DOI: 10.1523/Jneurosci.23-18-07227.2003  0.415
2003 Wanaverbecq N, Marsh SJ, Al-Qatari M, Brown DA. The plasma membrane calcium-ATPase as a major mechanism for intracellular calcium regulation in neurones from the rat superior cervical ganglion. The Journal of Physiology. 550: 83-101. PMID 12879862 DOI: 10.1113/Jphysiol.2002.035782  0.725
2003 Hadley JK, Passmore GM, Tatulian L, Al-Qatari M, Ye F, Wickenden AD, Brown DA. Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5012-9. PMID 12832524 DOI: 10.1523/Jneurosci.23-12-05012.2003  0.425
2003 Hoshi N, Zhang JS, Omaki M, Takeuchi T, Yokoyama S, Wanaverbecq N, Langeberg LK, Yoneda Y, Scott JD, Brown DA, Higashida H. AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists. Nature Neuroscience. 6: 564-71. PMID 12754513 DOI: 10.1038/Nn1062  0.763
2003 Tatulian L, Brown DA. Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells. The Journal of Physiology. 549: 57-63. PMID 12702739 DOI: 10.1113/Jphysiol.2003.039842  0.33
2003 Filippov AK, Simon J, Barnard EA, Brown DA. Coupling of the nucleotide P2Y4 receptor to neuronal ion channels. British Journal of Pharmacology. 138: 400-6. PMID 12540532 DOI: 10.1038/Sj.Bjp.0705043  0.474
2003 Barnard EA, Simon J, Tsim KWK, Filippov AK, Brown DA. Signalling pathways and ion channel regulations of P2Y receptors Drug Development Research. 59: 36-48. DOI: 10.1002/Ddr.10200  0.338
2002 Shah M, Mistry M, Marsh SJ, Brown DA, Delmas P. Molecular correlates of the M-current in cultured rat hippocampal neurons. The Journal of Physiology. 544: 29-37. PMID 12356878 DOI: 10.1113/Jphysiol.2002.028571  0.434
2002 Delmas P, Wanaverbecq N, Abogadie FC, Mistry M, Brown DA. Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons. Neuron. 34: 209-20. PMID 11970863 DOI: 10.1016/S0896-6273(02)00641-4  0.745
2002 Selyanko AA, Delmas P, Hadley JK, Tatulian L, Wood IC, Mistry M, London B, Brown DA. Dominant-negative subunits reveal potassium channel families that contribute to M-like potassium currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC212. PMID 11880533 DOI: 10.1523/Jneurosci.22-05-J0001.2002  0.417
2002 Delmas P, Nomura H, Li X, Lakkis M, Luo Y, Segal Y, Fernández-Fernández JM, Harris P, Frischauf AM, Brown DA, Zhou J. Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2. The Journal of Biological Chemistry. 277: 11276-83. PMID 11786542 DOI: 10.1074/Jbc.M110483200  0.316
2002 Brown DA, Selyanko AA, Hadley JK, Tatulian L. Neurophysiology. 34: 91-94. DOI: 10.1023/A:1020768914645  0.354
2001 Robbins MJ, Calver AR, Filippov AK, Hirst WD, Russell RB, Wood MD, Nasir S, Couve A, Brown DA, Moss SJ, Pangalos MN. GABA(B2) is essential for g-protein coupling of the GABA(B) receptor heterodimer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8043-52. PMID 11588177 DOI: 10.1523/Jneurosci.21-20-08043.2001  0.327
2001 Fernández-Fernández JM, Abogadie FC, Milligan G, Delmas P, Brown DA. Multiple pertussis toxin-sensitive G-proteins can couple receptors to GIRK channels in rat sympathetic neurons when expressed heterologously, but only native G(i)-proteins do so in situ. The European Journal of Neuroscience. 14: 283-92. PMID 11553279 DOI: 10.1046/J.0953-816X.2001.01642.X  0.417
2001 Selyanko AA, Hadley JK, Brown DA. Properties of single M-type KCNQ2/KCNQ3 potassium channels expressed in mammalian cells. The Journal of Physiology. 534: 15-24. PMID 11432988 DOI: 10.1111/J.1469-7793.2001.00015.X  0.382
2001 Pan Z, Selyanko AA, Hadley JK, Brown DA, Dixon JE, McKinnon D. Alternative splicing of KCNQ2 potassium channel transcripts contributes to the functional diversity of M-currents. The Journal of Physiology. 531: 347-58. PMID 11230508 DOI: 10.1111/J.1469-7793.2001.0347I.X  0.348
2001 Tatulian L, Delmas P, Abogadie FC, Brown DA. Activation of Expressed KCNQ Potassium Currents and Native Neuronal M-Type Potassium Currents by the Anti-Convulsant Drug Retigabine The Journal of Neuroscience. 21: 5535-5545. DOI: 10.1523/Jneurosci.21-15-05535.2001  0.46
2000 Higashida H, Brown DA, Robbins J. Both linopirdine- and WAY123,398-sensitive components of I K(M,ng) are modulated by cyclic ADP ribose in NG108-15 cells. PflüGers Archiv : European Journal of Physiology. 441: 228-34. PMID 11211107 DOI: 10.1007/S004240000433  0.446
2000 Kittler JT, Delmas P, Jovanovic JN, Brown DA, Smart TG, Moss SJ. Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7972-7. PMID 11050117 DOI: 10.1523/Jneurosci.20-21-07972.2000  0.626
2000 Brandon NJ, Delmas P, Kittler JT, McDonald BJ, Sieghart W, Brown DA, Smart TG, Moss SJ. GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway. The Journal of Biological Chemistry. 275: 38856-62. PMID 10978327 DOI: 10.1074/Jbc.M004910200  0.604
2000 Brown DA. Neurobiology: The acid test for resting potassium channels Current Biology. 10. PMID 10873797 DOI: 10.1016/S0960-9822(00)00532-7  0.379
2000 Brown DA, Filippov AK, Barnard EA. Inhibition of potassium and calcium currents in neurones by molecularly-defined P2Y receptors. Journal of the Autonomic Nervous System. 81: 31-6. PMID 10869697 DOI: 10.1016/S0165-1838(00)00150-8  0.483
2000 Delmas P, Abogadie FC, Buckley NJ, Brown DA. Calcium channel gating and modulation by transmitters depend on cellular compartmentalization. Nature Neuroscience. 3: 670-8. PMID 10862699 DOI: 10.1038/76621  0.383
2000 Filippov AK, Brown DA, Barnard EA. The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists. British Journal of Pharmacology. 129: 1063-6. PMID 10725253 DOI: 10.1038/Sj.Bjp.0703185  0.45
2000 Selyanko AA, Hadley JK, Wood IC, Abogadie FC, Jentsch TJ, Brown DA. Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors. The Journal of Physiology. 522: 349-55. PMID 10713961 DOI: 10.1111/J.1469-7793.2000.T01-2-00349.X  0.439
2000 Hadley JK, Noda M, Selyanko AA, Wood IC, Abogadie FC, Brown DA. Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels. British Journal of Pharmacology. 129: 413-5. PMID 10711337 DOI: 10.1038/Sj.Bjp.0703086  0.322
2000 Haley JE, Abogadie FC, Fernandez-Fernandez JM, Dayrell M, Vallis Y, Buckley NJ, Brown DA. Bradykinin, But Not Muscarinic, Inhibition of M-Current in Rat Sympathetic Ganglion Neurons Involves Phospholipase C-β4 The Journal of Neuroscience. 20: RC105-RC105. DOI: 10.1523/Jneurosci.20-21-J0003.2000  0.335
2000 Haley JE, Delmas P, Offermanns S, Abogadie FC, Simon MI, Buckley NJ, Brown DA. Muscarinic Inhibition of Calcium Current and M Current in Gαq-Deficient Mice The Journal of Neuroscience. 20: 3973-3979. DOI: 10.1523/Jneurosci.20-11-03973.2000  0.416
1999 Buckley NJ, Abogadie FC, Brown DA, Dayrell M, Caulfield MP, Delmas P, Haley JE. Use of antisense expression plasmids to attenuate G-protein expression in primary neurons Methods in Enzymology. 314: 136-148. PMID 10565010 DOI: 10.1016/S0076-6879(99)14100-4  0.313
1999 Selyanko AA, Brown DA. M-channel gating and simulation. Biophysical Journal. 77: 701-13. PMID 10423419 DOI: 10.1016/S0006-3495(99)76925-0  0.371
1999 Delmas P, Abogadie FC, Milligan G, Buckley NJ, Brown DA. betagamma dimers derived from Go and Gi proteins contribute different components of adrenergic inhibition of Ca2+ channels in rat sympathetic neurones. The Journal of Physiology. 518: 23-36. PMID 10373686 DOI: 10.1111/J.1469-7793.1999.0023R.X  0.431
1999 Filippov AK, Webb TE, Barnard EA, Brown DA. Dual coupling of heterologously-expressed rat P2Y6 nucleotide receptors to N-type Ca2+ and M-type K+ currents in rat sympathetic neurones. British Journal of Pharmacology. 126: 1009-17. PMID 10193782 DOI: 10.1038/Sj.Bjp.0702356  0.483
1999 Fernandez-Fernandez JM, Wanaverbecq N, Halley P, Caulfield MP, Brown DA. Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones Journal of Physiology. 515: 631-637. PMID 10066893 DOI: 10.1111/J.1469-7793.1999.631Ab.X  0.79
1999 Selyanko AA, Sim JA, Brown DA. Small (SKCa) Ca2+-activated K+ channels in cultured rat hippocampal pyramidal neurones. Pflugers Archiv : European Journal of Physiology. 437: 161-3. PMID 9817802 DOI: 10.1007/S004240050762  0.414
1999 Selyanko AA, Hadley JK, Wood IC, Abogadie FC, Delmas P, Buckley NJ, London B, Brown DA. Two Types of K+Channel Subunit, Erg1 and KCNQ2/3, Contribute to the M-Like Current in a Mammalian Neuronal Cell The Journal of Neuroscience. 19: 7742-7756. DOI: 10.1523/Jneurosci.19-18-07742.1999  0.432
1998 Couve A, Filippov AK, Connolly CN, Bettler B, Brown DA, Moss SJ. Intracellular retention of recombinant GABAB receptors. The Journal of Biological Chemistry. 273: 26361-7. PMID 9756866 DOI: 10.1074/Jbc.273.41.26361  0.385
1998 Filippov AK, Webb TE, Barnard EA, Brown DA. P2Y2 nucleotide receptors expressed heterologously in sympathetic neurons inhibit both N-type Ca2+ and M-type K+ currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5170-9. PMID 9651200 DOI: 10.1523/Jneurosci.18-14-05170.1998  0.498
1998 Delmas P, Brown DA, Dayrell M, Abogadie FC, Caulfield MP, Buckley NJ. On the role of endogenous G-protein beta gamma subunits in N-type Ca2+ current inhibition by neurotransmitters in rat sympathetic neurones. The Journal of Physiology. 319-29. PMID 9490860 DOI: 10.1111/J.1469-7793.1998.319Bw.X  0.364
1998 Haley JE, Abogadie FC, Delmas P, Dayrell M, Vallis Y, Milligan G, Caulfield MP, Brown DA, Buckley NJ. The α Subunit of GqContributes to Muscarinic Inhibition of the M-Type Potassium Current in Sympathetic Neurons The Journal of Neuroscience. 18: 4521-4531. DOI: 10.1523/Jneurosci.18-12-04521.1998  0.419
1997 Filippov AK, Webb TE, Barnard EA, Brown DA. Inhibition by heterologously-expressed P2Y2 nucleotide receptors of N-type calcium currents in rat sympathetic neurones. British Journal of Pharmacology. 121: 849-51. PMID 9222539 DOI: 10.1038/Sj.Bjp.0701270  0.413
1997 Leaney JL, Marsh SJ, Brown DA. A swelling-activated chloride current in rat sympathetic neurones. The Journal of Physiology. 555-64. PMID 9218216 DOI: 10.1111/J.1469-7793.1997.555Bm.X  0.452
1997 Brown DA, Forward A, Marsh S. Antagonist discrimination between ganglionic and ileal muscarinic receptors. 1980. British Journal of Pharmacology. 120: 447-9; discussion 44. PMID 9142423 DOI: 10.1111/J.1476-5381.1997.Tb06833.X  0.327
1997 Brown DA, Abogadie FC, Allen TGJ, Buckley NJ, Caulfield MP, Delmas P, Haley JE, Lamas JA, Selyanko AA. Muscarinic mechanisms in nerve cells Life Sciences. 60: 1137-1144. PMID 9121358 DOI: 10.1016/S0024-3205(97)00058-1  0.395
1997 Lamas JA, Selyanko AA, Brown DA. Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons. The European Journal of Neuroscience. 9: 605-16. PMID 9104602 DOI: 10.1111/J.1460-9568.1997.Tb01637.X  0.48
1997 Bowery NG, Brown DA. The cloning of GABA(B) receptors. Nature. 386: 223-4. PMID 9069276 DOI: 10.1038/386223A0  0.314
1997 Stansfeld C, Ludwig J, Roeper J, Weseloh R, Brown D, Pongs O. A physiological role for ether-à-go-go K+ channels? Trends in Neurosciences. 20: 13-4. PMID 9004412 DOI: 10.1016/S0166-2236(96)20058-X  0.353
1996 Allen TG, Brown DA. Detection and modulation of acetylcholine release from neurites of rat basal forebrain cells in culture. The Journal of Physiology. 492: 453-66. PMID 9019542 DOI: 10.1113/Jphysiol.1996.Sp021321  0.417
1996 Selyanko AA, Brown DA. Regulation of M-type potassium channels in mammalian sympathetic neurons: Action of intracellular calcium on single channel currents Neuropharmacology. 35: 933-947. PMID 8938724 DOI: 10.1016/0028-3908(96)00135-9  0.457
1996 Noda M, Ishizaka N, Yokoyama S, Hoshi N, Kimura Y, Hashii M, Taketo M, Egorova A, Knijnik R, Fukuda K, Morikawa H, Brown DA, Higashida H. Inositol trisphosphate/Ca2+ as messengers of bradykinin B2 and muscarinic acetylcholine m1-m4 receptors in neuroblastoma-derived hybrid cells. Journal of Lipid Mediators and Cell Signalling. 14: 175-85. PMID 8906560 DOI: 10.1016/0929-7855(96)00523-8  0.374
1996 Filippov AK, Brown DA. Activation of nucleotide receptors inhibits high-threshold calcium currents in NG108-15 neuronal hybrid cells. The European Journal of Neuroscience. 8: 1149-55. PMID 8752584 DOI: 10.1111/J.1460-9568.1996.Tb01282.X  0.46
1996 Filippov AK, Kozlov SA, Pluzhnikov KA, Grishin EV, Brown DA. M-type K+ current inhibition by a toxin fron the scorpion Buthus eupeus. Febs Letters. 384: 277-80. PMID 8617371 DOI: 10.1016/0014-5793(96)00333-X  0.393
1996 Selyanko AA, Brown DA. Intracellular calcium directly inhibits potassium M channels in excised membrane patches from rat sympathetic neurons Neuron. 16: 151-162. PMID 8562079 DOI: 10.1016/S0896-6273(00)80032-X  0.458
1995 Filippov AK, Selyanko AA, Robbins J, Brown DA. Activation of nucleotide receptors inhibits M-type K current [IK(M)] in neuroblastoma x glioma hybrid cells. Pflugers Archiv : European Journal of Physiology. 429: 223-30. PMID 7892108 DOI: 10.1007/Bf00374316  0.445
1995 Jones S, Brown DA, Milligan G, Willer E, Buckley NJ, Caulfield MP. Bradykinin excites rat sympathetic neurons by inhibition of M current through a mechanism involving B2 receptors and Gαq/11 Neuron. 14: 399-405. PMID 7857647 DOI: 10.1016/0896-6273(95)90295-3  0.452
1995 Ishizaka N, Noda M, Kimura Y, Hashii M, Fukuda K, Katayama M, Brown DA, Higashida H. Inositol 1,4,5-trisphosphate formation and ryanodine-sensitive oscillations of cytosolic free Ca2+ concentrations in neuroblastoma×fibroblast hybrid NL308 cells expressing m2 and m4 muscarinic acetylcholine receptor subtypes PflüGers Archiv European Journal of Physiology. 429: 426-433. PMID 7761266 DOI: 10.1007/Bf00374159  0.364
1995 Marsh SJ, Trouslard J, Leaney JL, Brown DA. Synergistic regulation of a neuronal chloride current by intracellular calcium and muscarinic receptor activation: A role for protein kinase C Neuron. 15: 729-737. PMID 7546751 DOI: 10.1016/0896-6273(95)90160-4  0.442
1994 Robbins J, Marsh SJ, Brown DA. On the mechanism of M-current inhibition by muscarinic m1 receptors in DNA-transfected rodent neuroblastoma x glioma cells. The Journal of Physiology. 469: 153-78. PMID 8271196 DOI: 10.1113/Jphysiol.1993.Sp019809  0.449
1994 Alger BE, Sim JA, Brown DA. Single-channel activity correlated with medium-duration, Ca-dependent K current in cultured rat hippocampal neurones. Neuroscience Letters. 168: 23-8. PMID 8028783 DOI: 10.1016/0304-3940(94)90407-3  0.455
1994 Caulfield MP, Jones S, Vallis Y, Buckley NJ, Kim GD, Milligan G, Brown DA. Muscarinic M-current inhibition via G(αq/11) and α-adrenoceptor inhibition of Ca2+ current via G(αo) in rat sympathetic neurones Journal of Physiology. 477: 415-422. PMID 7932231 DOI: 10.1113/Jphysiol.1994.Sp020203  0.308
1993 Brown DA, Higashida H, Noda M, Ishizaka N, Hashii M, Hoshi N, Yokoyama S, Fukuda K, Katayama M, Nukada T. Coupling of muscarinic receptor subtypes to ion channels: experiments on neuroblastoma hybrid cells. Annals of the New York Academy of Sciences. 707: 237-58. PMID 9137556 DOI: 10.1111/J.1749-6632.1993.Tb38056.X  0.322
1993 Civan MM, Robbins J, Broad S, Rozengurt E, Brown DA. Whole-cell recording of neuroblastoma x glioma cells during downregulation of a major substrate, 80K/MARCKS, of protein kinase C. The Journal of Membrane Biology. 133: 51-9. PMID 8320719 DOI: 10.1007/Bf00231877  0.417
1993 Caeser M, Brown DA, Gähwiler BH, Knöpfel T. Characterization of a calcium-dependent current generating a slow afterdepolarization of CA3 pyramidal cells in rat hippocampal slice cultures. The European Journal of Neuroscience. 5: 560-9. PMID 8261130 DOI: 10.1111/J.1460-9568.1993.Tb00521.X  0.423
1993 Trouslard J, Marsh SJ, Brown DA. Calcium entry through nicotinic receptor channels and calcium channels in cultured rat superior cervical ganglion cells The Journal of Physiology. 468: 53-71. PMID 8254522 DOI: 10.1113/Jphysiol.1993.Sp019759  0.421
1993 Selyanko AA, Brown DA. Effects of membrane potential and muscarine on potassium M-channel kinetics in rat sympathetic neurones Journal of Physiology. 472: 711-724. PMID 8145167 DOI: 10.1113/Jphysiol.1993.Sp019968  0.366
1993 Noda M, Katayama M, Brown DA, Robbins J, Marsh SJ, Ishizaka N, Fukuda K, Hoshi N, Yokoyama S, Higashida H. Coupling of m2 and m4 muscarinic acetylcholine receptor subtypes to Ca(2+)-dependent K+ channels in transformed NL308 neuroblastoma x fibroblast hybrid cells. Proceedings. Biological Sciences / the Royal Society. 251: 215-24. PMID 8097328 DOI: 10.1098/Rspb.1993.0032  0.396
1993 Cloues R, Jones S, Brown DA. Zn2+ potentiates ATP-activated currents in rat sympathetic neurons PflüGers Archiv European Journal of Physiology. 424: 152-158. PMID 7692385 DOI: 10.1007/Bf00374606  0.436
1993 Allen TG, Sim JA, Brown DA. The whole-cell calcium current in acutely dissociated magnocellular cholinergic basal forebrain neurones of the rat. The Journal of Physiology. 460: 91-116. PMID 7683720 DOI: 10.1113/Jphysiol.1993.Sp019461  0.435
1993 Stansfeld CE, Marsh SJ, Gibb AJ, Brown DA. Identification of M-channels in outside-out patches excised from sympathetic ganglion cells. Neuron. 10: 639-54. PMID 7682820 DOI: 10.1016/0896-6273(93)90166-O  0.426
1993 Caulfield MP, Robbins J, Higashida H, Brown DA. Postsynaptic actions of acetylcholine: The coupling of muscarinic receptor subtypes to neuronal ion channels Progress in Brain Research. 98: 293-301. PMID 7504311 DOI: 10.1016/S0079-6123(08)62411-5  0.411
1993 Selyanko AA, Stansfeld CE, Brown DA. Closure of potassium M-channels by muscarinic acetylcholine-receptor stimulants requires a diffusible messenger. Proceedings. Biological Sciences. 250: 119-25. PMID 1361985 DOI: 10.1098/Rspb.1992.0139  0.442
1993 Allen TGJ, Brown DA. M2 muscarinic receptor-mediated inhibition of the Ca2+ current in rat magnocellular cholinergic basal forebrain neurones. The Journal of Physiology. 466: 173-189. DOI: 10.1113/Jphysiol.1993.Sp019715  0.494
1993 Wood I, Buckley N, Brown D. Regulation of m4 muscarinic receptor gene expression Life Sciences. 52: 583. DOI: 10.1016/0024-3205(93)90382-D  0.307
1992 Sim JA, Gerber U, Knöpfel T, Brown DA. Evidence Against a Role for Protein Kinase C in the Inhibition of the Calcium-activated Potassium Current IAHP by Muscarinic Stimulants in Rat Hippocampal Neurons. The European Journal of Neuroscience. 4: 785-791. PMID 12106301 DOI: 10.1111/J.1460-9568.1992.Tb00188.X  0.396
1992 Marsh SJ, Brown DA. Potassium currents contributing to action potential repolarization in dissociated cultured rat superior cervical sympathetic neurones. Neuroscience Letters. 133: 298-302. PMID 1816510 DOI: 10.1016/0304-3940(91)90593-I  0.438
1992 Caulfield MP, Brown DA. Pharmacology of the putative M4 muscarinic receptor mediating Ca-current inhibition in neuroblastoma x glioma hybrid (NG 108-15) cells. British Journal of Pharmacology. 104: 39-44. PMID 1786516 DOI: 10.1111/J.1476-5381.1991.Tb12381.X  0.423
1992 Caulfield MP, Robbins J, Brown DA. Neurotransmitters inhibit the omega-conotoxin-sensitive component of Ca current in neuroblastoma x glioma hybrid (NG 108-15) cells, not the nifedipine-sensitive component. Pflugers Archiv : European Journal of Physiology. 420: 486-92. PMID 1614821 DOI: 10.1007/Bf00374623  0.403
1992 Laiwand R, Brown DA. Synapse formation between dissociated basal forebrain neurones and hippocampal cells in culture. Neuroscience Letters. 138: 221-4. PMID 1608532 DOI: 10.1016/0304-3940(92)90919-X  0.38
1992 Robbins J, Cloues R, Brown DA. Intracellular Mg2+ inhibits the IP3-activated IK(Ca) in NG108-15 cells. [Why intracellular citrate can be useful for recording IK(Ca)]. Pflugers Archiv : European Journal of Physiology. 420: 347-53. PMID 1598189 DOI: 10.1007/Bf00374469  0.354
1992 Robbins J, Trouslard J, Marsh SJ, Brown DA. Kinetic and pharmacological properties of the M‐current in rodent neuroblastoma x glioma hybrid cells The Journal of Physiology. 451: 159-185. PMID 1403809 DOI: 10.1113/Jphysiol.1992.Sp019159  0.441
1992 Jones S, Robbins J, Brown DA. Neurotransmitter modulation of calcium channels is dependent on the charge carrier used in the recording of currents Neuroscience Letters. 145: 153-156. PMID 1361221 DOI: 10.1016/0304-3940(92)90009-V  0.328
1992 Caulfield MP, Brown DA. Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. British Journal of Pharmacology. 106: 231-2. PMID 1327374 DOI: 10.1111/J.1476-5381.1992.Tb14321.X  0.436
1991 Owen DG, Marsh SJ, Brown DA. M-current noise and putative M-channels in cultured rat sympathetic ganglion cells. The Journal of Physiology. 431: 269-90. PMID 1712841 DOI: 10.1113/Jphysiol.1990.Sp018330  0.45
1991 Caulfield MP, Robbins J, Sim JA, Brown DA, Mac Neil S, Blackburn GM. The naphthalenesulphonamide calmodulin antagonist W7 and its 5-iodo-1-C8 analogue inhibit potassium and calcium currents in NG108-15 neuroblastoma x glioma cells in a manner possibly unrelated to their antagonism of calmodulin. Neuroscience Letters. 125: 57-61. PMID 1649984 DOI: 10.1016/0304-3940(91)90130-L  0.41
1991 Brown DA, Marsh SJ. Membrane currents in rat superior cervical sympathetic neurones Journal of the Autonomic Nervous System. 33: 155. DOI: 10.1016/0165-1838(91)90177-5  0.359
1990 Marsh SJ, Hubbard A, Brown DA. Some Actions of 9-Amino-1,2,3,4-Tetrahydroacridine (THA) on Cholinergic Transmission and Membrane Currents in Rat Sympathetic Ganglia. The European Journal of Neuroscience. 2: 1127-1134. PMID 12106073 DOI: 10.1111/J.1460-9568.1990.Tb00024.X  0.457
1990 McFadzean I, Mullaney I, Brown DA, Milligan G. Antibodies to the GTP binding protein, Go, antagonize noradrenaline-induced calcium current inhibition in NG108-15 hybrid cells. Neuron. 3: 177-82. PMID 2560391 DOI: 10.1016/0896-6273(89)90030-5  0.322
1990 Knöpfel T, Charpak S, Brown DA, Gähwiler BH. Cytosolic free calcium in hippocampal CA3 pyramidal cells. Progress in Brain Research. 83: 189-95. PMID 2203098 DOI: 10.1016/S0079-6123(08)61249-2  0.378
1990 Brown DA, Gähwiler BH, Griffith WH, Halliwell JV. Membrane currents in hippocampal neurons. Progress in Brain Research. 83: 141-60. PMID 2203096 DOI: 10.1016/S0079-6123(08)61247-9  0.435
1990 Higashida H, Hashii M, Fukuda K, Caulfield MP, Numa S, Brown DA. Selective coupling of different muscarinic acetylcholine receptors to neuronal calcium currents in DNA-transfected cells. Proceedings. Biological Sciences / the Royal Society. 242: 68-74. PMID 1980742 DOI: 10.1098/Rspb.1990.0105  0.408
1990 Brown DA. G-proteins and potassium currents in neurons Annual Review of Physiology. 52: 215-242. PMID 1970470 DOI: 10.1146/Annurev.Ph.52.030190.001243  0.353
1990 Marsh SJ, Hubbard A, Brown DA. Some actions of 9-amino-1,2,3,4- tetrahydroacridine (THA) on cholinergic transmission and membrane currents in rat sympathetic ganglia European Journal of Neuroscience. 2: 1127-1134. DOI: 10.1111/j.1460-9568.1990.tb00024.x  0.349
1989 Marrion NV, Smart TG, Marsh SJ, Brown DA. Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype. British Journal of Pharmacology. 98: 557-73. PMID 2819334 DOI: 10.1111/J.1476-5381.1989.Tb12630.X  0.683
1989 Brown DA, Marrion NV, Smart TG. On the transduction mechanism for muscarine-induced inhibition of M-current in cultured rat sympathetic neurones. The Journal of Physiology. 413: 469-88. PMID 2689633 DOI: 10.1113/Jphysiol.1989.Sp017664  0.654
1989 Elliott P, Marsh SJ, Brown DA. Inhibition of Ca-spikes in rat preganglionic cervical sympathetic nerves by sympathomimetic amines. British Journal of Pharmacology. 96: 65-76. PMID 2538183 DOI: 10.1111/J.1476-5381.1989.Tb11785.X  0.41
1988 Brown DA, Higashida H, Adams PR, Marrion NV, Smart TG. Role of G-protein-coupled phosphatidylinositide system in signal transduction in vertebrate neurons: experiments on neuroblastoma hybrid cells and ganglion cells. Cold Spring Harbor Symposia On Quantitative Biology. 53: 375-84. PMID 2855484 DOI: 10.1101/Sqb.1988.053.01.045  0.659
1988 Brown D. M-currents: an update Trends in Neurosciences. 11: 294-299. PMID 2465631 DOI: 10.1016/0166-2236(88)90089-6  0.343
1988 Griffith WH, Hills JM, Brown DA. Substance P-mediated membrane currents in voltage-clamped guinea pig inferior mesenteric ganglion cells. Synapse (New York, N.Y.). 2: 432-41. PMID 2460961 DOI: 10.1002/Syn.890020411  0.431
1987 Bourque CW, Brown DA. Apamin and d-tubocurarine block the afterhyperpolarization of rat supraoptic neurosecretory neurons. Neuroscience Letters. 82: 185-90. PMID 3696492 DOI: 10.1016/0304-3940(87)90127-3  0.636
1987 Marsh SJ, Stansfeld CE, Brown DA, Davey R, McCarthy D. The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro Neuroscience. 23: 275-289. PMID 3683864 DOI: 10.1016/0306-4522(87)90289-2  0.372
1987 Marrion NV, Smart TG, Brown DA. Membrane currents in adult rat superior cervical ganglia in dissociated tissue culture. Neuroscience Letters. 77: 55-60. PMID 3601217 DOI: 10.1016/0304-3940(87)90606-9  0.617
1987 Gähwiler BH, Brown DA. Muscarine affects calcium-currents in rat hippocampal pyramidal cells in vitro. Neuroscience Letters. 76: 301-6. PMID 3587761 DOI: 10.1016/0304-3940(87)90419-8  0.446
1987 Brown DA, Adams PR. Effects of phorbol dibutyrate on M currents and M current inhibition in bullfrog sympathetic neurons. Cellular and Molecular Neurobiology. 7: 255-69. PMID 2449965 DOI: 10.1007/Bf00711303  0.668
1987 Stansfeld CE, Marsh SJ, Parcej DN, Dolly JO, Brown DA. Mast cell degranulating peptide and dendrotoxin selectively inhibit a fast-activating potassium current and bind to common neuronal proteins. Neuroscience. 23: 893-902. PMID 2449637 DOI: 10.1016/0306-4522(87)90166-7  0.387
1987 Gähwiler BH, Brown DA. Effects of dihydropyridines on calcium currents in CA3 pyramidal cells in slice cultures of rat hippocampus. Neuroscience. 20: 731-8. PMID 2439942 DOI: 10.1016/0306-4522(87)90236-3  0.425
1987 Van Renterghem C, Bilbe G, Moss S, Smart TG, Constanti A, Brown DA, Barnard EA. GABA receptors induced in Xenopus oocytes by chick brain mRNA: evaluation of TBPS as a use-dependent channel-blocker. Brain Research. 388: 21-31. PMID 2437999 DOI: 10.1016/0169-328X(87)90017-9  0.623
1986 Smart TG, Constanti A, Houamed K, Bilbe G, Brown DA, Barnard EA, VanRenterghem C. Expression of vertebrate amino acid receptors in Xenopus oocytes. Advances in Experimental Medicine and Biology. 203: 525-37. PMID 3024460 DOI: 10.1007/978-1-4684-7971-3_41  0.561
1986 Adams PR, Jones SW, Pennefather P, Brown DA, Koch C, Lancaster B. Slow synaptic transmission in frog sympathetic ganglia. The Journal of Experimental Biology. 124: 259-85. PMID 3020147  0.578
1986 Bourque CW, Brown DA, Renaud LP. Barium ions induce prolonged plateau depolarizations in neurosecretory neurones of the adult rat supraoptic nucleus. The Journal of Physiology. 375: 573-86. PMID 2432227 DOI: 10.1113/Jphysiol.1986.Sp016134  0.726
1986 Docherty RJ, Brown DA. Excitatory action of BAYK8644 on hippocampal pyramidal neurones of the guinea pig in vitro. Neuroscience Letters. 70: 239-44. PMID 2430239 DOI: 10.1016/0304-3940(86)90470-2  0.422
1986 Docherty RJ, Brown DA. Interaction of 1,4-dihydropyridines with somatic Ca currents in hippocampal CA1 neurones of the guinea pig in vitro. Neuroscience Letters. 70: 110-5. PMID 2430236 DOI: 10.1016/0304-3940(86)90447-7  0.426
1986 Higashida H, Brown DA. Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell. Nature. 323: 333-5. PMID 2429190 DOI: 10.1038/323333A0  0.465
1986 Stansfeld CE, Marsh SJ, Halliwell JV, Brown DA. 4-Aminopyridine and dendrotoxin induce repetitive firing in rat visceral sensory neurones by blocking a slowly inactivating outward current. Neuroscience Letters. 64: 299-304. PMID 2421213 DOI: 10.1016/0304-3940(86)90345-9  0.445
1985 Gahwiler BH, Brown DA. Functional innervation of cultured hippocampal neurones by cholinergic afferents from co-cultured septal explants. Nature. 313: 577-9. PMID 3969160 DOI: 10.1038/313577A0  0.395
1985 Gähwiler BH, Brown DA. GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures. Proceedings of the National Academy of Sciences of the United States of America. 82: 1558-62. PMID 2983351 DOI: 10.1073/Pnas.82.5.1558  0.476
1985 Brown DA, Selyanko AA. Two components of muscarine‐sensitive membrane current in rat sympathetic neurones The Journal of Physiology. 358: 335-363. PMID 2580084 DOI: 10.1113/jphysiol.1985.sp015554  0.333
1985 Brown DA, Adams PR, Jones SW, Griffith WH, Hills J, Constanti A. Some ionic mechanisms of slow peptidergic neuronal excitation. Regulatory Peptides. Supplement. 4: 157-64. PMID 2414812  0.528
1985 Brown DA, Selyanko AA. Membrane currents underlying the cholinergic slow excitatory post‐synaptic potential in the rat sympathetic ganglion The Journal of Physiology. 365: 365-387. PMID 2411921 DOI: 10.1113/jphysiol.1985.sp015777  0.321
1984 Brown DA, Docherty RJ, Halliwell JV. The action of cholinomimetic substances on impulse conduction in the habenulointerpeduncular pathway of the rat in vitro. The Journal of Physiology. 353: 101-9. PMID 6481621 DOI: 10.1113/Jphysiol.1984.Sp015325  0.322
1984 Brown DA, Scholfield CN. Inhibition of GABA uptake potentiates the conductance increase produced by GABA-mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea-pig. British Journal of Pharmacology. 83: 195-202. PMID 6237704 DOI: 10.1111/J.1476-5381.1984.Tb10135.X  0.371
1984 Brown DA, Dunn PM. Depolarization of rat isolated superior cervical ganglia mediated by beta 2-adrenoceptors. British Journal of Pharmacology. 79: 429-39. PMID 6140042 DOI: 10.1111/J.1476-5381.1983.Tb11016.X  0.389
1984 Barnard EA, Beeson D, Bilbe G, Brown DA, Constanti A, Houamed K, Smart TG. A system for the translation of receptor messenger-RNA and the study of the assembly of functional receptors. Journal of Receptor Research. 4: 681-704. PMID 6098676 DOI: 10.3109/10799898409042581  0.522
1984 Barnard EA, Stephenson FA, Sigel E, Mamalaki C, Bilbe G, Constanti A, Smart TG, Brown DA. Structure and properties of the brain GABA/benzodiazepine receptor complex. Advances in Experimental Medicine and Biology. 175: 235-54. PMID 6093456 DOI: 10.1007/978-1-4684-4805-4_19  0.588
1984 Houamed KM, Bilbe G, Smart TG, Constanti A, Brown DA, Barnard EA, Richards BM. Expression of functional GABA, glycine and glutamate receptors in Xenopus oocytes injected with rat brain mRNA. Nature. 310: 318-21. PMID 6087151 DOI: 10.1038/310318A0  0.587
1983 Brown DA, Griffith WH. Persistent slow inward calcium current in voltage-clamped hippocampal neurones of the guinea-pig. The Journal of Physiology. 337: 303-20. PMID 6875932 DOI: 10.1113/Jphysiol.1983.Sp014625  0.445
1983 Brown DA, Griffith WH. Calcium-activated outward current in voltage-clamped hippocampal neurones of the guinea-pig. The Journal of Physiology. 337: 287-301. PMID 6875931 DOI: 10.1113/Jphysiol.1983.Sp014624  0.45
1983 Barnard EA, Beeson D, Bilbe G, Brown DA, Constanti A, Conti-Tronconi BM, Dolly JO, Dunn SM, Mehraban F, Richards BM. Acetylcholine and GABA receptors: subunits of central and peripheral receptors and their encoding nucleic acids. Cold Spring Harbor Symposia On Quantitative Biology. 48: 109-24. PMID 6327147 DOI: 10.1101/Sqb.1983.048.01.014  0.334
1983 Brown DA, Constanti A, Adams PR. Ca-activated potassium current in vertebrate sympathetic neurons. Cell Calcium. 4: 407-20. PMID 6323003 DOI: 10.1016/0143-4160(83)90017-9  0.645
1983 Brown DA, Dunn PM. Cyclic adenosine 3′,5′‐monophosphate and β‐effects in rat isolated superior cervical ganglia British Journal of Pharmacology. 79: 441-449. PMID 6317111 DOI: 10.1111/J.1476-5381.1983.Tb11017.X  0.357
1983 Smart TG, Constanti A, Bilbe G, Brown DA, Barnard EA. Synthesis of functional chick brain GABA-benzodiazepine-barbiturate/receptor complexes in mRNA-injected Xenopus oocytes. Neuroscience Letters. 40: 55-9. PMID 6314204 DOI: 10.1016/0304-3940(83)90092-7  0.596
1983 Adams PR, Brown DA, Jones SW. Substance P inhibits the M-current in bullfrog sympathetic neurones. British Journal of Pharmacology. 79: 330-3. PMID 6197122 DOI: 10.1111/J.1476-5381.1983.Tb11004.X  0.66
1983 Brown DA, Docherty RJ, Halliwell JV. Chemical transmission in the rat interpeduncular nucleus in vitro. The Journal of Physiology. 341: 655-70. PMID 6137562 DOI: 10.1113/Jphysiol.1983.Sp014831  0.352
1982 Adams PR, Brown DA. Synaptic inhibition of the M-current: slow excitatory post-synaptic potential mechanism in bullfrog sympathetic neurones. The Journal of Physiology. 332: 263-72. PMID 6984074 DOI: 10.1113/Jphysiol.1982.Sp014412  0.616
1982 Adams PR, Brown DA, Constanti A. Pharmacological inhibition of the M-current. The Journal of Physiology. 332: 223-62. PMID 6760380 DOI: 10.1113/Jphysiol.1982.Sp014411  0.648
1982 Adams PR, Brown DA, Constanti A. M-currents and other potassium currents in bullfrog sympathetic neurones. The Journal of Physiology. 330: 537-72. PMID 6294290 DOI: 10.1113/Jphysiol.1982.Sp014357  0.623
1982 Adams PR, Constanti A, Brown DA, Clark RB. Intracellular Ca2+ activates a fast voltage-sensitive K+ current in vertebrate sympathetic neurones. Nature. 296: 746-9. PMID 6280066 DOI: 10.1038/296746A0  0.668
1982 Brown DA, Adams PR, Constanti A. Voltage-sensitive K-currents in sympathetic neurons and their modulation by neurotransmitters. Journal of the Autonomic Nervous System. 6: 23-35. PMID 6127362 DOI: 10.1016/0165-1838(82)90019-4  0.652
1981 Constanti A, Brown DA. M-currents in voltage-clamped mammalian sympathetic neurones Neuroscience Letters. 24: 289-294. PMID 7279296 DOI: 10.1016/0304-3940(81)90173-7  0.457
1981 Brown DA, Higgins AJ, Marsh S, Smart TG. Actions of GABA on mammalian neurones, axons, and nerve terminals. Advances in Biochemical Psychopharmacology. 29: 321-6. PMID 7020367  0.532
1981 Constanti A, Adams PR, Brown DA. Who do barium ions imitate acetylcholine? Brain Research. 206: 244-50. PMID 6970607 DOI: 10.1016/0006-8993(81)90125-6  0.616
1981 Brown DA, Constanti A, Adams PR. Slow cholinergic and peptidergic transmission in sympathetic ganglia. Federation Proceedings. 40: 2625-30. PMID 6268462  0.629
1980 Brown DA, Constanti A. Intracellular observations on the effects of muscarinic agonists on rat sympathetic neurones British Journal of Pharmacology. 70: 593-608. PMID 7470731 DOI: 10.1111/j.1476-5381.1980.tb09778.x  0.347
1980 Brown DA, Adams PR. Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature. 283: 673-6. PMID 6965523 DOI: 10.1038/283673A0  0.672
1980 Adams PR, Brown DA. Luteinizing hormone-releasing factor and muscarinic agonists act on the same voltage-sensitive K+-current in bullfrog sympathetic neurones. British Journal of Pharmacology. 68: 353-5. PMID 6762900  0.625
1980 Brown DA, Fatherazi S, Garthwaite J, White RD. Muscarinic receptors in rat sympathetic ganglia. British Journal of Pharmacology. 70: 577-92. PMID 6258681 DOI: 10.1111/J.1476-5381.1980.Tb09777.X  0.385
1980 Brown DA, Constanti A, Marsh S. Angiotensin mimics the action of muscarinic agonists on rat sympathetic neurones. Brain Research. 193: 614-619. PMID 6248170 DOI: 10.1016/0006-8993(80)90200-0  0.365
1980 Brown DA, Collins GG, Galvan M. Influence of cellular transport on the interaction of amino acids with gamma-aminobutyric acid (GABA)-receptors in the isolated olfactory cortex of the guinea-pig. British Journal of Pharmacology. 68: 251-62. PMID 6244038 DOI: 10.1111/J.1476-5381.1980.Tb10414.X  0.329
1980 Brown D, Galvan M, Scholfield C. Depolarization of neurones in slices of the olfactory cortex of the guinea-pig by GABA Brain Research Bulletin. 5: 291-293. DOI: 10.1016/0361-9230(80)90048-9  0.393
1979 Brown DA, Galvan M. Responses of the guinea-pig isolated olfactory cortex slice to gamma-aminobutyric acid recorded with extracellular electrodes. British Journal of Pharmacology. 65: 347-53. PMID 760907 DOI: 10.1111/J.1476-5381.1979.Tb07836.X  0.324
1979 Adams PR, Brown DA. Appendix to gamma-Aminobutyric acid efflux from sympathetic glial cells: effect of depolarizing agents. Electrical responses of presumed sympathetic neuroglial cells to K+ ions and to preganglionic nerve stimulation. The Journal of Physiology. 293: 95-8. PMID 501660  0.524
1979 Bowery NG, Brown DA, Marsh S. gamma-Aminobutyric acid efflux from sympathetic glial cells: effect of 'depolarizing' agents. The Journal of Physiology. 293: 75-101. PMID 501652 DOI: 10.1113/Jphysiol.1979.Sp012879  0.374
1979 Bowery NG, Brown DA, White RD, Yamini G. [3H]gamma-Aminobutyric acid uptake into neuroglial cells of rat superior cervical sympathetic ganglia. The Journal of Physiology. 293: 51-74. PMID 501628 DOI: 10.1113/Jphysiol.1979.Sp012878  0.35
1979 Brown DA, Adams PR, Higgins AJ, Marsh S. Distribution of gaba-receptors and gaba-carriers in the mammalian nervous system. Journal De Physiologie. 75: 667-71. PMID 232722  0.586
1979 Brown DA, Caulfield MP, Kirby PJ. Relation between catecholamine-induced cyclic AMP changes and hyperpolarization in isolated rat sympathetic ganglia. The Journal of Physiology. 290: 441-51. PMID 224171 DOI: 10.1113/Jphysiol.1979.Sp012782  0.343
1979 Brown DA, Caulfield MP. Hyperpolarizing `α2'-adrenoceptors in rat sympathetic ganglia British Journal of Pharmacology. 65: 435-445. PMID 218668 DOI: 10.1111/J.1476-5381.1979.Tb07848.X  0.374
1979 Brown DA, Scholfield CN. Depolarization of neurones in the isolated olfactory cortex of the guinea-pig by gamma-aminobutyric acid. British Journal of Pharmacology. 65: 339-45. PMID 216454 DOI: 10.1111/J.1476-5381.1979.Tb07835.X  0.398
1979 Brown DA. Extrasynaptic GABA systems Trends in Neurosciences. 2: 271-273. DOI: 10.1016/0166-2236(79)90107-3  0.323
1978 Brown DA, Constanti A. Interaction of pentobarbitone and γ-aminobutyric acid on mammalian sympathetic ganglion cells British Journal of Pharmacology. 63: 217-224. PMID 647160 DOI: 10.1111/J.1476-5381.1978.Tb07791.X  0.368
1977 Brown DA, Galvan M. Influence of neuroglial transport on the action of gamma-aminobutyric acid on mammalian ganglion cells. British Journal of Pharmacology. 59: 373-8. PMID 189874 DOI: 10.1111/J.1476-5381.1977.Tb07502.X  0.336
1976 Bowery NG, Brown DA, Collins GG, Galvan M, Marsh S, Yamini G. Indirect effects of amino-acids on sympathetic ganglion cells mediated through the release of gamma-aminobutyric acid from glial cells. British Journal of Pharmacology. 57: 73-91. PMID 1276543 DOI: 10.1111/J.1476-5381.1976.Tb07658.X  0.354
1976 Brown DA, Kwiatkowski D. A note on the effect of dithiothreitol (DTT) on the depolarization of isolated sympathetic ganglia by carbachol and bromo acetylcholine British Journal of Pharmacology. 56: 128-130. PMID 1252660 DOI: 10.1111/J.1476-5381.1976.Tb06968.X  0.351
1976 Brown DA, Garthwaite J. Action of surugatoxin on nicotinic receptors in the superior cervical ganglion of the rat. British Journal of Pharmacology. 58: 157-9. PMID 974373 DOI: 10.1111/J.1476-5381.1976.Tb07705.X  0.384
1975 Adams PR, Brown DA. Actions of gamma-aminobutyric acid on sympathetic ganglion cells. The Journal of Physiology. 250: 85-120. PMID 1177140 DOI: 10.1113/Jphysiol.1975.Sp011044  0.6
1975 Bowery NG, Brown DA, Collins JF. Tetramethylenedisulphotetramine: an inhibitor of gamma-aminobutyric acid induced depolarization of the isolated superior cervical ganglion of the rat. British Journal of Pharmacology. 53: 422-4. PMID 165847 DOI: 10.1111/J.1476-5381.1975.Tb07379.X  0.348
1974 Adams PR, Brown DA. Proceedings: Some observations on electrically-inexcitable cells (neuroglia?) in rat sympathetic ganglia. British Journal of Pharmacology. 51: 131P-132P. PMID 4155329  0.49
1973 Adams PR, Brown DA. Action of -aminobutyric acid (GABA) on rat sympathetic ganglion cells. British Journal of Pharmacology. 47: 639P-640P. PMID 4730853  0.547
Low-probability matches (unlikely to be authored by this person)
2002 Abogadie FC, Bron R, Marsh SJ, Drew LJ, Haley JE, Buckley NJ, Brown DA, Delmas P. Adenovirus-mediated G(alpha)(q)-protein antisense transfer in neurons replicates G(alpha)(q) gene knockout strategies. Neuropharmacology. 42: 950-7. PMID 12069905 DOI: 10.1016/S0028-3908(02)00044-8  0.299
1994 McFadzean I, Caulfield MP, Vallis Y, Brown DA. Injection of antisera into cells to study G-protein regulation of channel function. Methods in Enzymology. 238: 357-364. PMID 7528321 DOI: 10.1016/0076-6879(94)38032-5  0.298
2010 Brown DA, Passmore GM. Some new insights into the molecular mechanisms of pain perception. The Journal of Clinical Investigation. 120: 1380-3. PMID 20424321 DOI: 10.1172/Jci42143  0.296
2002 Simon J, Filippov AK, Göransson S, Wong YH, Frelin C, Michel AD, Brown DA, Barnard EA. Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells. The Journal of Biological Chemistry. 277: 31390-400. PMID 12080041 DOI: 10.1074/Jbc.M110714200  0.29
1997 Momiyama T, Sim JA, Brown DA. Dopamine D1-like receptor-mediated presynaptic inhibition of excitatory transmission onto rat magnocellular basal forebrain neurones. The Journal of Physiology. 97-106. PMID 8866354 DOI: 10.1113/jphysiol.1996.sp021576  0.287
2019 Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM. The subthreshold-active K7 current regulates neurotransmission by limiting spike-induced Ca influx in hippocampal mossy fiber synaptic terminals. Communications Biology. 2: 145. PMID 31924985 DOI: 10.1038/s42003-019-0408-4  0.276
2019 Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM. The subthreshold-active K7 current regulates neurotransmission by limiting spike-induced Ca influx in hippocampal mossy fiber synaptic terminals. Communications Biology. 2: 145. PMID 31044170 DOI: 10.1038/s42003-019-0408-4  0.276
2002 Delmas P, Brown DA. Junctional signaling microdomains: bridging the gap between the neuronal cell surface and Ca2+ stores. Neuron. 36: 787-90. PMID 12467583 DOI: 10.1016/S0896-6273(02)01097-8  0.274
1993 Trouslard J, Mirsky R, Jessen KR, Burnstock G, Brown DA. Intracellular calcium changes associated with cholinergic nicotinic receptor activation in cultured myenteric plexus neurones. Brain Research. 624: 103-8. PMID 8252380 DOI: 10.1016/0006-8993(93)90065-U  0.27
1972 Brown DA, Brownstein MJ, Scholfield CN. Origin of the after-hyperpolarization that follows removal of depolarizing agents from the isolated superior cervical ganglion of the rat. British Journal of Pharmacology. 44: 651-71. PMID 4625268 DOI: 10.1111/j.1476-5381.1972.tb07305.x  0.265
1987 Brown D. Gaps in progress Nature. 330: 529-529. DOI: 10.1038/330529A0  0.264
1994 Xu X, Brown DA, Kitajima I, Bilakovics J, Fey LW, Nerenberg MI. Transcriptional suppression of the human T-cell leukemia virus type I long terminal repeat occurs by an unconventional interaction of a CREB factor with the R region. Molecular and Cellular Biology. 14: 5371-5383. PMID 8035815 DOI: 10.1128/mcb.14.8.5371-5383.1994  0.262
2006 Allen TG, Abogadie FC, Brown DA. Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1588-95. PMID 16452682 DOI: 10.1523/Jneurosci.3979-05.2006  0.257
1992 Sim JA, Gerber U, Knopfel T, Brown DA. Evidence against a role for protein kinase C in the inhibition of the calcium-activated potassium current I(AHP) by muscarinic stimulants in rat hippocampal neurons European Journal of Neuroscience. 4: 785-791. DOI: 10.1111/j.1460-9568.1992.tb00188.x  0.256
1995 Higashida H, Robbins J, Egorova A, Noda M, Taketo M, Ishizaka N, Takasawa S, Okamoto H, Brown DA. Nicotinamide-adenine dinucleotide regulates muscarinic receptor-coupled K+ (M) channels in rodent NG108-15 cells Journal of Physiology. 482: 317-323. PMID 7714825 DOI: 10.1113/jphysiol.1995.sp020520  0.254
2010 Romanenko VG, Catalán MA, Brown DA, Putzier I, Hartzell HC, Marmorstein AD, Gonzalez-Begne M, Rock JR, Harfe BD, Melvin JE. Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. The Journal of Biological Chemistry. 285: 12990-3001. PMID 20177062 DOI: 10.1074/Jbc.M109.068544  0.253
1983 Brown DA. Slow cholinergic excitation - a mechanism for increasing neuronal excitability Trends in Neurosciences. 6: 302-307. DOI: 10.1016/0166-2236(83)90144-3  0.25
2000 Filippov AK, Couve A, Pangalos MN, Walsh FS, Brown DA, Moss SJ. Heteromeric assembly of GABA(B)R1 and GABA(B)R2 receptor subunits inhibits Ca(2+) current in sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2867-74. PMID 10751439  0.246
1982 Brown D. Peptidergic transmission in ganglia Trends in Neurosciences. 5: 34-35. DOI: 10.1016/0166-2236(82)90014-5  0.242
2004 Brown DA, Bruce JI, Straub SV, Yule DI. cAMP potentiates ATP-evoked calcium signaling in human parotid acinar cells. The Journal of Biological Chemistry. 279: 39485-94. PMID 15262999 DOI: 10.1074/Jbc.M406201200  0.241
1991 Brown D. Brain cholinergic systems: edited by M. Steriade and D. Biesold, Oxford University Press, 1990. £65.00 (xxii + 446 pages) ISBN 0 19 854266 6 Trends in Neurosciences. 14: 533. DOI: 10.1016/0166-2236(91)90007-H  0.24
2004 Delmas P, Nauli SM, Li X, Coste B, Osorio N, Crest M, Brown DA, Zhou J. Gating of the polycystin ion channel signaling complex in neurons and kidney cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 740-2. PMID 14766803 DOI: 10.1096/fj.03-0319fje  0.238
2001 Korolkova YV, Kozlov SA, Lipkin AV, Pluzhnikov KA, Hadley JK, Filippov AK, Brown DA, Angelo K, Strøbaek D, Jespersen T, Olesen SP, Jensen BS, Grishin EV. An ERG channel inhibitor from the scorpion Buthus eupeus. The Journal of Biological Chemistry. 276: 9868-76. PMID 11136720 DOI: 10.1074/Jbc.M005973200  0.236
1990 Knöpfel T, Vranesic I, Gähwiler BH, Brown DA. Muscarinic and beta-adrenergic depression of the slow Ca2(+)-activated potassium conductance in hippocampal CA3 pyramidal cells is not mediated by a reduction of depolarization-induced cytosolic Ca2+ transients. Proceedings of the National Academy of Sciences of the United States of America. 87: 4083-7. PMID 2161530  0.23
1990 Luini A, Brown DA. Effects of corticotrophin releasing factor, muscarine and somatostatin on rubidium and potassium efflux from mouse AtT-20 pituitary cells European Journal of Neuroscience. 2: 126-131. DOI: 10.1111/j.1460-9568.1990.tb00404.x  0.229
2009 Dunn C, Peppa D, Khanna P, Nebbia G, Jones M, Brendish N, Lascar RM, Brown D, Gilson R, Tedder R, Dusheiko G, Jacobs M, Klenerman P, Maini M. Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology. 137: 1289-1300. PMID 19591831 DOI: 10.1053/J.Gastro.2009.06.054  0.227
1996 Xu X, Kang S, Heidenreich O, Brown DA, Nerenberg MI. Sequence Requirements of ATF2 and CREB Binding to the Human T-Cell Leukemia Virus Type 1 LTR R Region Virology. 218: 362-371. PMID 8610463 DOI: 10.1006/Viro.1996.0205  0.226
2007 Brown DA, Yule DI. Protein kinase C regulation of P2X3 receptors is unlikely to involve direct receptor phosphorylation. Biochimica Et Biophysica Acta. 1773: 166-75. PMID 17052768 DOI: 10.1016/J.Bbamcr.2006.09.020  0.224
2013 Fujimoto H, Liu HX, Lopatina O, Brown DA, Higashida H. Scopolamine modulates paternal parental retrieval behavior in mice induced by the maternal mate. Neuroscience Letters. 546: 63-6. PMID 23669641 DOI: 10.1016/J.Neulet.2013.04.059  0.223
1996 Kang S, Brown DA, Kitajima I, Xu X, Heidenreich O, Gryaznov S, Nerenberg M. Binding and functional effects of transcriptional factor Sp1 on the murine interleukin-6 promotor. Journal of Biological Chemistry. 271: 7330-7335. PMID 8631753 DOI: 10.1074/Jbc.271.13.7330  0.222
1972 Bowery NG, Brown DA. -Aminobutyrylcholine: actions on GABA and acetylcholine receptors. The Journal of Pharmacy and Pharmacology. 24: 663-6. PMID 4403753  0.219
1996 Brown DA, Xu X, Nerenberg M. Genomic Footprinting of HTLV Type I and HIV Type 1 in Human T Cell Lines Aids Research and Human Retroviruses. 12: 829-832. PMID 8738435 DOI: 10.1089/Aid.1996.12.829  0.216
2013 Ala A, Brown D, Khan K, Standish R, Odin JA, Fiel MI, Schiano TD, Hillan KJ, Rahman SA, Hodgson HJ, Dhillon AP. Mucosal addressin cell adhesion molecule (MAdCAM-1) expression is upregulated in the cirrhotic liver and immunolocalises to the peribiliary plexus and lymphoid aggregates. Digestive Diseases and Sciences. 58: 2528-41. PMID 23839340 DOI: 10.1007/S10620-013-2755-1  0.216
1974 Bowery NG, Brown DA. Depolarizing actions of gamma-aminobutyric acid and related compounds on rat superior cervical ganglia in vitro. British Journal of Pharmacology. 50: 205-18. PMID 4154116  0.215
1988 Brown DA. M currents Ion Channels. 1: 55-94. PMID 3155026 DOI: 10.1007/978-1-4615-7302-9_2  0.215
1984 Brown D, Hallinan T. Cryosensitization and cryoprotection of hepatic microsomal membranes Biochemical Society Transactions. 12: 680-681. DOI: 10.1042/Bst0120680  0.214
2008 Bungay A, Selden C, Brown D, Malik R, Hubank M, Hodgson H. Microarray analysis of mitogenic effects of T3 on the rat liver. Journal of Gastroenterology and Hepatology. 23: 1926-33. PMID 18717759 DOI: 10.1111/J.1440-1746.2008.05506.X  0.214
1995 Heidenreich O, Kang SH, Brown DA, Xu X, Swiderski P, Rossi JJ, Eckstein F, Nerenberg M. Ribozyme-mediated RNA degradation in nuclei suspension Nucleic Acids Research. 23: 2223-2228. PMID 7610051 DOI: 10.1093/Nar/23.12.2223  0.214
1978 Jones CA, Reeves A, Scott JD, Brown DA. Comparison of Root Activity in Vegetative and Reproductive Soybean Plants1 Agronomy Journal. 70: 751-755. DOI: 10.2134/Agronj1978.00021962007000050014X  0.205
2008 Rossoni E, Feng J, Tirozzi B, Brown D, Leng G, Moos F. Emergent synchronous bursting of oxytocin neuronal network. Plos Computational Biology. 4: e1000123. PMID 18636098 DOI: 10.1371/Journal.Pcbi.1000123  0.204
1975 Brown DA, Scholfield CN. Changes of intracellular sodium and potassium ion concentrations in isolated rat superior cervical ganglia induced by depolarizing agents. The Journal of Physiology. 242: 307-19. PMID 4455814 DOI: 10.1113/jphysiol.1974.sp010709  0.201
1985 BROWN D, HALLINAN T. Enzyme topology in native, intact endoplasmic reticulum of permeabilized isolated hepatocytes Biochemical Society Transactions. 13: 721-722. DOI: 10.1042/Bst0130721  0.2
2015 Mazza G, Rombouts K, Rennie Hall A, Urbani L, Vinh Luong T, Al-Akkad W, Longato L, Brown D, Maghsoudlou P, Dhillon AP, Fuller B, Davidson B, Moore K, Dhar D, De Coppi P, et al. Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation. Scientific Reports. 5: 13079. PMID 26248878 DOI: 10.1038/Srep13079  0.199
1990 Lee HJ, Hammond DN, Large TH, Roback JD, Sim JA, Brown DA, Otten UH, Wainer BH. Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1779-87. PMID 2113086  0.196
2019 Birdsall NJM, Bradley S, Brown DA, Buckley NJ, Challiss RJ, Christopoulos A, Eglen RM, Ehlert F, Felder CC, Hammer R, Kilbinger HJ, Lambrecht G, Langmead C, Mitchelson F, Mutschler E, et al. Acetylcholine receptors (muscarinic) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f2/2019.4  0.195
2017 Lane CA, Parker TD, Cash DM, Macpherson K, Donnachie E, Murray-Smith H, Barnes A, Barker S, Beasley DG, Bras J, Brown D, Burgos N, Byford M, Jorge Cardoso M, Carvalho A, et al. Study protocol: Insight 46 - a neuroscience sub-study of the MRC National Survey of Health and Development. Bmc Neurology. 17: 75. PMID 28420323 DOI: 10.1186/S12883-017-0846-X  0.193
1969 Brown DA. Responses of normal and denervated cat superior cervical ganglia to some stimulant compounds The Journal of Physiology. 201: 225-236. PMID 5773557 DOI: 10.1113/jphysiol.1969.sp008752  0.193
2014 Tsai VW, Manandhar R, Jørgensen SB, Lee-Ng KK, Zhang HP, Marquis CP, Jiang L, Husaini Y, Lin S, Sainsbury A, Sawchenko PE, Brown DA, Breit SN. The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract. Plos One. 9: e100370. PMID 24971956 DOI: 10.1371/Journal.Pone.0100370  0.191
1989 Brown DA, Docherty RJ, McFadzean I. Calcium channels in vertebrate neurons. Experiments on a neuroblastoma hybrid model. Annals of the New York Academy of Sciences. 560: 358-72. PMID 2545143 DOI: 10.1111/j.1749-6632.1989.tb24115.x  0.191
2013 Liu HX, Lopatina O, Higashida C, Fujimoto H, Akther S, Inzhutova A, Liang M, Zhong J, Tsuji T, Yoshihara T, Sumi K, Ishiyama M, Ma WJ, Ozaki M, Yagitani S, ... ... Brown DA, et al. Displays of paternal mouse pup retrieval following communicative interaction with maternal mates. Nature Communications. 4: 1346. PMID 23299896 DOI: 10.1038/Ncomms2336  0.189
1988 Brown DA. Need for speed of transmission Nature. 335: 475-475. DOI: 10.1038/335475A0  0.187
2003 Mace LC, Palmer BM, Brown DA, Jew KN, Lynch JM, Glunt JM, Parsons TA, Cheung JY, Moore RL. Influence of age and run training on cardiac Na+/Ca2+ exchange. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1994-2003. PMID 12882992 DOI: 10.1152/japplphysiol.00551.2003  0.187
2010 Liu T, Brown DA, O'Rourke B. Role of mitochondrial dysfunction in cardiac glycoside toxicity. Journal of Molecular and Cellular Cardiology. 49: 728-36. PMID 20620145 DOI: 10.1016/j.yjmcc.2010.06.012  0.186
2010 Brown DA, Yule DI. Protein kinase A regulation of P2X(4) receptors: requirement for a specific motif in the C-terminus. Biochimica Et Biophysica Acta. 1803: 275-87. PMID 20026202 DOI: 10.1016/J.Bbamcr.2009.12.002  0.185
1990 Atta MO, Smith BG, Brown D. Bond strengths of three chemical adhesive cements adhered to a nickel-chromium alloy for direct bonded retainers. The Journal of Prosthetic Dentistry. 63: 137-43. PMID 2406422 DOI: 10.1016/0022-3913(90)90096-U  0.181
2017 Brown D. Are new approaches needed for developing long-term strategies for STEM information? Learned Publishing. 30: 237-243. DOI: 10.1002/Leap.1103  0.18
2003 Brown DA, Melvin JE, Yule DI. Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G804-12. PMID 12842825 DOI: 10.1152/Ajpgi.00150.2003  0.174
1985 Williams SH, Constanti A, Brown DA. Muscarinic depression of evoked surface-negative field potentials recorded from guinea-pig olfactory cortex in vitro Neuroscience Letters. 56: 301-306. PMID 2862610 DOI: 10.1016/0304-3940(85)90259-9  0.169
2014 Brown DA, Betharia S, Yen JH, Tran Q, Mistry H, Smith K. Synthesis and structure-activity relationships study of dithiolethiones as inducers of glutathione in the SH-SY5Y neuroblastoma cell line. Bioorganic & Medicinal Chemistry Letters. 24: 5829-31. PMID 25455499 DOI: 10.1016/j.bmcl.2014.10.005  0.168
1975 Brown DA, Scholfield CN. Movements of labelled sodium ions in isolated rat superior cervical ganglia. The Journal of Physiology. 242: 321-51. PMID 4455816 DOI: 10.1113/jphysiol.1974.sp010710  0.166
1989 Gähwiler BH, Brown DA, Enz A, Knöpfel T. Development of the septohippocampal projection in vitro. Exs. 57: 236-50. PMID 2533095  0.166
2004 Liu S, Brown CW, Berlin KD, Dhar A, Guruswamy S, Brown D, Gardner GJ, Birrer MJ, Benbrook DM. Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells. Journal of Medicinal Chemistry. 47: 999-1007. PMID 14761202 DOI: 10.1021/Jm030346V  0.165
1971 Brown DA, Halliwell JV, Scholfield CN. Uptake of nicotine and extracellular space markers by isolated rat ganglia in relation to receptor activation. British Journal of Pharmacology. 42: 100-13. PMID 5580695 DOI: 10.1111/j.1476-5381.1971.tb07090.x  0.164
1983 Brown DA, Docherty JR, French AM, MacDonald A, McGrath JC, Scott NC. Separation of adrenergic and non-adrenergic contractions to field stimulation in the rat vas deferens. British Journal of Pharmacology. 79: 379-93. PMID 6317108 DOI: 10.1111/J.1476-5381.1983.Tb11010.X  0.164
1996 Brown D. Individuals' rights and wrongs. Nature. 383: 474-474. PMID 8849713 DOI: 10.1038/383474A0  0.162
2012 Jiang L, Salao K, Li H, Rybicka JM, Yates RM, Luo XW, Shi XX, Kuffner T, Tsai VW, Husaini Y, Wu L, Brown DA, Grewal T, Brown LJ, Curmi PM, et al. Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification. Journal of Cell Science. 125: 5479-88. PMID 22956539 DOI: 10.1242/Jcs.110072  0.16
2010 Brown DA, Aon MA, Frasier CR, Sloan RC, Maloney AH, Anderson EJ, O'Rourke B. Cardiac arrhythmias induced by glutathione oxidation can be inhibited by preventing mitochondrial depolarization. Journal of Molecular and Cellular Cardiology. 48: 673-9. PMID 19962380 DOI: 10.1016/j.yjmcc.2009.11.011  0.157
2014 Giordanetto F, Bach P, Zetterberg F, Antonsson T, Bylund R, Johansson J, Sellén M, Brown D, Hideståhl L, Berntsson P, Hovdal D, Zachrisson H, Björkman JA, van Giezen JJ. Optimization of ketone-based P2Y(12) receptor antagonists as antithrombotic agents: pharmacodynamics and receptor kinetics considerations. Bioorganic & Medicinal Chemistry Letters. 24: 2963-8. PMID 24835983 DOI: 10.1016/j.bmcl.2014.04.001  0.156
2019 Brown DA. Acetylcholine and cholinergic receptors. Brain and Neuroscience Advances. 3: 2398212818820506. PMID 32166177 DOI: 10.1177/2398212818820506  0.154
2023 Breit SN, Manandhar R, Zhang HP, Lee-Ng M, Brown DA, Tsai VW. GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway. Cell Metabolism. PMID 37433299 DOI: 10.1016/j.cmet.2023.06.009  0.152
2018 Tsai VWW, Husaini Y, Sainsbury A, Brown DA, Breit SN. The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases. Cell Metabolism. 28: 353-368. PMID 30184485 DOI: 10.1016/J.Cmet.2018.07.018  0.151
2006 Brown DA. Acetylcholine. British Journal of Pharmacology. 147: S120-6. PMID 16402095 DOI: 10.1038/sj.bjp.0706474  0.15
2007 Klein R, Brown D, Turnley AM. Phenoxodiol protects against Cisplatin induced neurite toxicity in a PC-12 cell model. Bmc Neuroscience. 8: 61. PMID 17672914 DOI: 10.1186/1471-2202-8-61  0.15
2021 Brown D, Altermatt M, Dobreva T, Chen S, Wang A, Thomson M, Gradinaru V. Deep Parallel Characterization of AAV Tropism and AAV-Mediated Transcriptional Changes Single-Cell RNA Sequencing. Frontiers in Immunology. 12: 730825. PMID 34759919 DOI: 10.3389/fimmu.2021.730825  0.15
2005 Brown DA, Chicco AJ, Jew KN, Johnson MS, Lynch JM, Watson PA, Moore RL. Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. The Journal of Physiology. 569: 913-24. PMID 16223762 DOI: 10.1113/Jphysiol.2005.095729  0.148
2019 Tsai VW, Zhang HP, Manandhar R, Schofield P, Christ D, Lee-Ng KKM, Lebhar H, Marquis CP, Husaini Y, Brown DA, Breit SN. GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS. International Journal of Obesity (2005). PMID 31152154 DOI: 10.1038/S41366-019-0365-5  0.146
2003 Wang L, Connelly MA, Ostermeyer AG, Chen HH, Williams DL, Brown DA. Caveolin-1 does not affect SR-BI-mediated cholesterol efflux or selective uptake of cholesteryl ester in two cell lines. Journal of Lipid Research. 44: 807-15. PMID 12562842 DOI: 10.1194/jlr.M200449-JLR200  0.143
1972 Brown DA, Scholfield CN. Nicotine washout rates from isolated rat ganglia in relation to recovery from nicotine depolarization. British Journal of Pharmacology. 45: 29-36. PMID 5041505 DOI: 10.1111/j.1476-5381.1972.tb09573.x  0.142
2011 Lin HY, Landersdorfer CB, London D, Meng R, Lim CU, Lin C, Lin S, Tang HY, Brown D, Van Scoy B, Kulawy R, Queimado L, Drusano GL, Louie A, Davis FB, et al. Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system. Plos Computational Biology. 7: e1001073. PMID 21304935 DOI: 10.1371/Journal.Pcbi.1001073  0.142
2020 King DR, Padget RL, Perry J, Hoeker G, Smyth JW, Brown DA, Poelzing S. Elevated perfusate [Na] increases contractile dysfunction during ischemia and reperfusion. Scientific Reports. 10: 17289. PMID 33057157 DOI: 10.1038/s41598-020-74069-x  0.14
2008 Abboud MA, Needle SJ, Burns-Kurtis CL, Valocik RE, Koster PF, Amour AJ, Chan C, Brown D, Chaudry L, Zhou P, Patikis A, Patel C, Pateman AJ, Young RJ, Watson NS, et al. Antithrombotic potential of GW813893: a novel, orally active, active-site directed factor Xa inhibitor. Journal of Cardiovascular Pharmacology. 52: 66-71. PMID 18645410 DOI: 10.1097/Fjc.0B013E31817E9B9E  0.139
2020 Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V. Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. Nature Methods. PMID 32313222 DOI: 10.1038/S41592-020-0799-7  0.138
2014 Chicco AJ, Brown DA. "Roid-Rage" at the cellular level: abolition of endogenous cardioprotection by anabolic steroids reveals new links between the RAAS and cardiac KATP channels : editorial to: "AT1 and aldosterone receptors blockade prevents the chronic effect of nandrolone on the exercise-induced cardioprotection in perfused rat heart subjected to ischemia and reperfusion" by S.R. Marques-Neto et al. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 28: 113-4. PMID 24578227 DOI: 10.1007/S10557-014-6514-0  0.135
2010 Brown DA, O'Rourke B. Cardiac mitochondria and arrhythmias. Cardiovascular Research. 88: 241-9. PMID 20621924 DOI: 10.1093/cvr/cvq231  0.134
2010 Tan B, Brown D, Xu S, Valle D. PHR1 is a vesicle-bound protein abundantly expressed in mature olfactory neurons. Laryngoscope. 120: 1002-1010. PMID 20301200 DOI: 10.1002/Lary.20779  0.132
2016 Salao K, Jiang L, Li H, Tsai VW, Husaini Y, Curmi PM, Brown LJ, Brown DA, Breit SN. CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis. Biology Open. PMID 27113959 DOI: 10.1242/Bio.018119  0.131
2006 Johnson MS, Moore RL, Brown DA. Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2644-47. PMID 16473955 DOI: 10.1152/ajpheart.01291.2005  0.13
2010 Verma P, Ostermeyer-Fay AG, Brown DA. Caveolin-1 induces formation of membrane tubules that sense actomyosin tension and are inhibited by polymerase I and transcript release factor/cavin-1. Molecular Biology of the Cell. 21: 2226-40. PMID 20427576 DOI: 10.1091/mbc.E09-05-0417  0.13
2003 Davison AP, Feng J, Brown D. Dendrodendritic inhibition and simulated odor responses in a detailed olfactory bulb network model. Journal of Neurophysiology. 90: 1921-35. PMID 12736241 DOI: 10.1152/Jn.00623.2002  0.129
1974 Walsh JM, Bowery NG, Brown DA, Clark JB. Metabolism of gamma-aminobutyric acid (GABA) by peripheral nervous tissue. Journal of Neurochemistry. 22: 1145-7. PMID 4853184 DOI: 10.1111/j.1471-4159.1974.tb04350.x  0.129
2023 Shay TF, Sullivan EE, Ding X, Chen X, Ravindra Kumar S, Goertsen D, Brown D, Crosby A, Vielmetter J, Borsos M, Wolfe DA, Lam AW, Gradinaru V. Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances. 9: eadg6618. PMID 37075114 DOI: 10.1126/sciadv.adg6618  0.128
2015 Brown DA. PIP2Clustering: From model membranes to cells. Chemistry and Physics of Lipids. PMID 26232664 DOI: 10.1016/j.chemphyslip.2015.07.021  0.128
1971 Steward EG, Player R, Quilliam JP, Brown DA, Pringle MJ. Molecular conformation of GABA. Nature: New Biology. 233: 87-8. PMID 5287002  0.127
2009 Boyd RS, Jukes-Jones R, Walewska R, Brown D, Dyer MJ, Cain K. Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma. Molecular & Cellular Proteomics : McP. 8: 1501-15. PMID 19346216 DOI: 10.1074/mcp.M800515-MCP200  0.125
2004 Sharma R, Brown D, Awasthi S, Yang Y, Sharma A, Patrick B, Saini MK, Singh SP, Zimniak P, Singh SV, Awasthi YC. Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. European Journal of Biochemistry / Febs. 271: 1690-701. PMID 15096208 DOI: 10.1111/J.1432-1033.2004.04067.X  0.123
1972 Brown DA, Halliwell JV. Intracellular pH in rat isolated superior cervical ganglia in relation to nicotine-depolarization and nicotine-uptake. British Journal of Pharmacology. 45: 349-59. PMID 5048652 DOI: 10.1111/j.1476-5381.1972.tb08088.x  0.123
2007 Gin E, Crampin EJ, Brown DA, Shuttleworth TJ, Yule DI, Sneyd J. A mathematical model of fluid secretion from a parotid acinar cell. Journal of Theoretical Biology. 248: 64-80. PMID 17559884 DOI: 10.1016/J.Jtbi.2007.04.021  0.122
1969 Brown DA, Hoffmann PC, Roth LJ. 3H-Nicotine in cat superior cervical and nodose ganglia after close-arterial injection in vivo. British Journal of Pharmacology. 35: 406-17. PMID 5809733 DOI: 10.1111/j.1476-5381.1969.tb08282.x  0.122
2003 Liu T, Bauskin AR, Zaunders J, Brown DA, Pankhurst S, Russell PJ, Breit SN, Panhurst S. Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Research. 63: 5034-40. PMID 12941831  0.121
2024 Gillespie ER, Grice LF, Courtney IG, Lao HW, Jung W, Ramkomuth S, Xie J, Brown DA, Walsham J, Radford KJ, Nguyen QH, Ruitenberg MJ. Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems. Journal of Neuroinflammation. 21: 63. PMID 38429643 DOI: 10.1186/s12974-024-03048-0  0.12
2009 Brown DA, Mishra M, Zhang S, Biswas S, Parrington I, Antonio T, Reith ME, Dutta AK. Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor. Bioorganic & Medicinal Chemistry. 17: 3923-33. PMID 19427222 DOI: 10.1016/J.Bmc.2009.04.031  0.12
2003 Tallman RD, Dumond M, Brown D. Inflammatory mediator removal by zero-balance ultrafiltration during cardiopulmonary bypass. Perfusion. 17: 111-5. PMID 11958301 DOI: 10.1191/0267659102pf540oa  0.119
1979 Brown DA, Garthwaite J. Intracellular pH and the distribution of weak acids and bases in isolated rat superior cervical ganglia. The Journal of Physiology. 297: 597-620. PMID 43889  0.119
2006 Gamble JR, Xia P, Hahn CN, Drew JJ, Drogemuller CJ, Brown D, Vadas MA. Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects. International Journal of Cancer. Journal International Du Cancer. 118: 2412-20. PMID 16353157 DOI: 10.1002/Ijc.21682  0.116
2017 Breit SN, Tsai VW, Brown DA. Targeting Obesity and Cachexia: Identification of the GFRAL Receptor-MIC-1/GDF15 Pathway. Trends in Molecular Medicine. PMID 29129392 DOI: 10.1016/J.Molmed.2017.10.005  0.116
2009 Kotecha R, Pardos M, Wang Y, Wu T, Horn P, Brown D, Rose D, deGrauw T, Xiang J. Modeling the developmental patterns of auditory evoked magnetic fields in children. Plos One. 4: e4811. PMID 19277207 DOI: 10.1371/Journal.Pone.0004811  0.116
2014 Ahrens K, Brown DA, Kramer A. Convergence of m-bonacci 'golden ratios' International Journal of Mathematical Education in Science and Technology. 45: 618-624. DOI: 10.1080/0020739X.2013.851810  0.116
2015 McClung JM, Reinardy JL, Mueller SB, McCord TJ, Kontos CD, Brown DA, Hussain SN, Schmidt CA, Ryan TE, Green TD. Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment. Frontiers in Physiology. 6: 161. PMID 26042050 DOI: 10.3389/Fphys.2015.00161  0.114
2015 Brown DA. Preparation of detergent-resistant membranes (DRMs) from cultured mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1232: 55-64. PMID 25331127 DOI: 10.1007/978-1-4939-1752-5_5  0.113
2015 Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, Lim CK, Guillemin GJ, Brew BJ. Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease. Plos One. 10: e0131389. PMID 26114426 DOI: 10.1371/Journal.Pone.0131389  0.11
2009 Boyle GM, Pedley J, Martyn AC, Banducci KJ, Strutton GM, Brown DA, Breit SN, Parsons PG. Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity. The Journal of Investigative Dermatology. 129: 383-91. PMID 18754039 DOI: 10.1038/Jid.2008.270  0.109
1974 Harvey JA, Scholfield CN, Brown DA. Evoked surface-positive potentials in isolated mammalian olfactory cortex. Brain Research. 76: 235-45. PMID 4844456 DOI: 10.1016/0006-8993(74)90457-0  0.109
2018 Lee B, Kramer D, Armenta Salas M, Kellis S, Brown D, Dobreva T, Klaes C, Heck C, Liu C, Andersen RA. Engineering Artificial Somatosensation Through Cortical Stimulation in Humans. Frontiers in Systems Neuroscience. 12: 24. PMID 29915532 DOI: 10.3389/Fnsys.2018.00024  0.108
2009 Aon MA, Cortassa S, Akar FG, Brown DA, Zhou L, O'Rourke B. From mitochondrial dynamics to arrhythmias. The International Journal of Biochemistry & Cell Biology. 41: 1940-8. PMID 19703656 DOI: 10.1016/J.Biocel.2009.02.016  0.108
2010 Rimland J, Dunne A, Hunjan SS, Sasse R, Uings I, Montanari D, Caivano M, Shah P, Standing D, Gray D, Brown D, Cairns W, Trump R, Smith PW, Bertheleme N, et al. The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 20: 2340-3. PMID 20202837 DOI: 10.1016/J.Bmcl.2010.01.133  0.108
2007 Brown DA, Sawchenko PE. Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. The Journal of Comparative Neurology. 502: 236-60. PMID 17348011 DOI: 10.1002/Cne.21307  0.107
2008 Brown DA, Aon MA, Akar FG, Liu T, Sorarrain N, O'Rourke B. Effects of 4'-chlorodiazepam on cellular excitation-contraction coupling and ischaemia-reperfusion injury in rabbit heart. Cardiovascular Research. 79: 141-9. PMID 18304929 DOI: 10.1093/cvr/cvn053  0.106
2021 Bandara AB, Brown DA, Drake JC, James CC, Smyth JW. Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. Mitochondrion. PMID 33744462 DOI: 10.1016/j.mito.2021.03.003  0.105
2007 Brown DA. Analysis of raft affinity of membrane proteins by detergent-insolubility. Methods in Molecular Biology (Clifton, N.J.). 398: 9-20. PMID 18214370 DOI: 10.1007/978-1-59745-513-8_2  0.105
2011 Tsai VW, Mohammad MG, Tolhurst O, Breit SN, Sawchenko PE, Brown DA. CCAAT/enhancer binding protein-δ expression by dendritic cells regulates CNS autoimmune inflammatory disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17612-21. PMID 22131422 DOI: 10.1523/Jneurosci.3449-11.2011  0.105
2014 Zhu J, Lin F, Brown DA, Clark RA. A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signals. The Journal of Investigative Dermatology. 134: 921-9. PMID 24304816 DOI: 10.1038/jid.2013.463  0.104
2002 Donaldson K, Brown D, Clouter A, Duffin R, MacNee W, Renwick L, Tran L, Stone V. The Pulmonary Toxicology of Ultrafine Particles Journal of Aerosol Medicine-Deposition Clearance and Effects in the Lung. 15: 213-220. PMID 12184871 DOI: 10.1089/089426802320282338  0.103
2006 Yarosh DB, Galvin JW, Nay SL, Peña AV, Canning MT, Brown DA. Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine. Journal of Dermatological Science. 42: 13-21. PMID 16423507 DOI: 10.1016/J.Jdermsci.2005.12.009  0.103
2005 Ovcharenko D, Jarvis R, Hunicke-Smith S, Kelnar K, Brown D. High-throughput RNAi screening in vitro: from cell lines to primary cells. Rna (New York, N.Y.). 11: 985-93. PMID 15923380 DOI: 10.1261/rna.7288405  0.103
2008 Barr DJ, Ostermeyer-Fay AG, Matundan RA, Brown DA. Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells. Journal of Cell Science. 121: 3155-66. PMID 18765569 DOI: 10.1242/jcs.020404  0.102
2009 Brown DA, Cascio WE. 'Leaky' ryanodine receptors and sudden cardiac death. Cardiovascular Research. 84: 343-4. PMID 19815562 DOI: 10.1093/cvr/cvp330  0.101
2019 Padhi A, Thomson AH, Perry JB, Davis GN, McMillan RP, Loesgen S, Kaweesa EN, Kapania R, Nain AS, Brown DA. Bioenergetics underlying single cell migration on aligned nanofiber scaffolds. American Journal of Physiology. Cell Physiology. PMID 31875698 DOI: 10.1152/Ajpcell.00221.2019  0.101
2007 Turner S, Gallois P, Brown D. Tracheary Element Differentiation Annual Review of Plant Biology. 58: 407-433. PMID 17472568 DOI: 10.1146/Annurev.Arplant.57.032905.105236  0.101
2008 Brown DA, Kharkar PS, Parrington I, Reith ME, Dutta AK. Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]quinoline moieties for dopamine D2 and D3 receptors: binding characterization at D2/D3 receptors and elucidation of a pharmacophore model. Journal of Medicinal Chemistry. 51: 7806-19. PMID 19053758 DOI: 10.1021/Jm8008629  0.1
2005 Oshitari T, Brown D, Roy S. SiRNA strategy against overexpression of extracellular matrix in diabetic retinopathy Experimental Eye Research. 81: 32-37. PMID 15978252 DOI: 10.1016/J.Exer.2005.01.006  0.1
2009 Malik R, Bungay A, Sadiq A, Brown D, Riemann M, Choudhury S, Schmid R, Selden C, Hodgson H. The Role of the Bcl-3 Proto-Oncogene in Thyroid Hormone-Induced Liver Cell Proliferation Artificial Organs. 33: 425-430. PMID 19473137 DOI: 10.1111/J.1525-1594.2009.00752.X  0.099
2014 Zeczycki TN, Whelan J, Hayden WT, Brown DA, Shaikh SR. Increasing levels of cardiolipin differentially influence packing of phospholipids found in the mitochondrial inner membrane. Biochemical and Biophysical Research Communications. 450: 366-71. PMID 24905496 DOI: 10.1016/J.Bbrc.2014.05.133  0.099
2020 Tea F, Pilli D, Ramanathan S, Lopez JA, Merheb V, Lee FXZ, Zou A, Liyanage G, Bassett CB, Thomsen S, Reddel SW, Barnett MH, Brown DA, Dale RC, Brilot F, et al. Effects of the Positive Threshold and Data Analysis on Human MOG Antibody Detection by Live Flow Cytometry. Frontiers in Immunology. 11: 119. PMID 32117270 DOI: 10.3389/Fimmu.2020.00119  0.099
2003 Tatton WG, Chalmers-Redman R, Brown D, Tatton N. Apoptosis in Parkinson's disease: signals for neuronal degradation. Annals of Neurology. 53: S61-70; discussion S. PMID 12666099 DOI: 10.1002/ana.10489  0.099
2010 Korostenskaja M, Pardos M, Fujiwara H, Kujala T, Horn P, Rose D, Byars A, Brown D, Seo JH, Wang Y, Vannest J, Xiang J, Degrauw T, Näätänen R, Lee KH. Neuromagnetic evidence of impaired cortical auditory processing in pediatric intractable epilepsy. Epilepsy Research. 92: 63-73. PMID 20863661 DOI: 10.1016/J.Eplepsyres.2010.08.008  0.099
2003 Kamsteeg M, Rutherford T, Sapi E, Hanczaruk B, Shahabi S, Flick M, Brown D, Mor G. Phenoxodiol--an isoflavone analog--induces apoptosis in chemoresistant ovarian cancer cells. Oncogene. 22: 2611-20. PMID 12730675 DOI: 10.1038/sj.onc.1206422  0.098
1972 Bowery NG, Brown DA. -Aminobutyric acid uptake by sympathetic ganglia. Nature: New Biology. 238: 89-91. PMID 4505419  0.098
1990 Brown DA. Regulation of cell excitability Current Opinion in Cell Biology. 2: 221-230. PMID 1694673 DOI: 10.1016/0955-0674(90)90010-C  0.098
2008 Alvero AB, Kelly M, Rossi P, Leiser A, Brown D, Rutherford T, Mor G. Anti-tumor activity of phenoxodiol: from bench to clinic. Future Oncology (London, England). 4: 475-82. PMID 18684059 DOI: 10.2217/14796694.4.4.475  0.096
2022 Zammit NW, McDowell J, Warren J, Muskovic W, Gamble J, Shi YC, Kaczorowski D, Chan CL, Powell J, Ormandy C, Brown D, Oakes SR, Grey ST. TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation. Frontiers in Immunology. 13: 811525. PMID 35464428 DOI: 10.3389/fimmu.2022.811525  0.095
2021 Mariottoni P, Jiang SW, Prestwood CA, Jain V, Suwanpradid J, Whitley MJ, Coates M, Brown DA, Erdmann D, Corcoran DL, Gregory SG, Jaleel T, Zhang JY, Harris-Tryon TA, MacLeod AS. Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa. Frontiers in Medicine. 8: 665873. PMID 34504848 DOI: 10.3389/fmed.2021.665873  0.095
2004 Feng J, Brown D. Decoding input signals in time domain--a model approach. Journal of Computational Neuroscience. 16: 237-49. PMID 15114048 DOI: 10.1023/B:Jcns.0000025687.78916.5A  0.094
2003 Lademann U, Cain K, Gyrd-Hansen M, Brown D, Peters D, Jäättelä M. Diarylurea compounds inhibit caspase activation by preventing the formation of the active 700-kilodalton apoptosome complex. Molecular and Cellular Biology. 23: 7829-37. PMID 14560026 DOI: 10.1128/MCB.23.21.7829-7837.2003  0.094
2007 Alvero AB, Brown D, Montagna M, Matthews M, Mor G. Phenoxodiol-topotecan co-administration exhibit significant anti-tumor activity without major adverse side effects Cancer Biology and Therapy. 6: 612-617. PMID 17457041  0.093
2012 Louie A, Castanheira M, Liu W, Grasso C, Jones RN, Williams G, Critchley I, Thye D, Brown D, Vanscoy B, Kulawy R, Drusano GL. Pharmacodynamics of β-lactamase inhibition by NXL104 in combination with ceftaroline: examining organisms with multiple types of β-lactamases. Antimicrobial Agents and Chemotherapy. 56: 258-70. PMID 22024819 DOI: 10.1128/Aac.05005-11  0.093
2021 Tulpule A, Guan J, Neel DS, Allegakoen HR, Lin YP, Brown D, Chou YT, Heslin A, Chatterjee N, Perati S, Menon S, Nguyen TA, Debnath J, Ramirez AD, Shi X, et al. Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules. Cell. PMID 33848463 DOI: 10.1016/j.cell.2021.03.031  0.092
2017 Low JK, Ambikairajah A, Shang K, Brown DA, Tsai VW, Breit SN, Karl T. First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15. Plos One. 12: e0168416. PMID 28081177 DOI: 10.1371/Journal.Pone.0168416  0.092
2003 Keelan JA, Wang K, Chaiworapongsa T, Romero R, Mitchell MD, Sato TA, Brown DA, Fairlie WD, Breit SN. Macrophage inhibitory cytokine 1 in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes. Molecular Human Reproduction. 9: 535-40. PMID 12900512 DOI: 10.1093/Molehr/Gag068  0.092
2020 Dai P, Campbell D, Culican S, Brown DA, Byth K, Hissaria P, Ninnes R, Nankivell B, Lin MW. Validation of phospholipase A receptor direct immunofluorescence staining in the diagnosis of primary membranous glomerulonephritis. Pathology. PMID 32564921 DOI: 10.1016/J.Pathol.2020.04.003  0.091
2007 Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Research. 67: 7713-22. PMID 17699775 DOI: 10.1158/0008-5472.Can-07-1083  0.091
2018 Dai P, Campbell D, Culican S, McDonald D, Hissaria P, Ninnes R, Brown D, Lin M. Validation of renal biopsy phospholipase A2 receptor staining on direct immunofluorescence in the diagnosis of primary membranous glomerulonephritis Pathology. 50: S43. DOI: 10.1016/J.Pathol.2017.12.099  0.09
2004 Antonicelli F, Brown D, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson K, MacNee W. Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L1319-27. PMID 15136298 DOI: 10.1152/Ajplung.00329.2003  0.09
2014 Mohammad MG, Tsai VW, Ruitenberg MJ, Hassanpour M, Li H, Hart PH, Breit SN, Sawchenko PE, Brown DA. Immune cell trafficking from the brain maintains CNS immune tolerance. The Journal of Clinical Investigation. 124: 1228-41. PMID 24569378 DOI: 10.1172/Jci71544  0.09
2018 Bitner BF, Ray JD, Kener KB, Herring JA, Tueller JA, Johnson DK, Tellez Freitas CM, Fausnacht DW, Allen ME, Thomson AH, Weber KS, McMillan RP, Hulver MW, Brown DA, Tessem JS, et al. Common gut microbial metabolites of dietary flavonoids exert potent protective activities in β-cells and skeletal muscle cells. The Journal of Nutritional Biochemistry. 62: 95-107. PMID 30286378 DOI: 10.1016/J.Jnutbio.2018.09.004  0.09
2014 Gucwa AL, Brown DA. UIM domain-dependent recruitment of the endocytic adaptor protein Eps15 to ubiquitin-enriched endosomes. Bmc Cell Biology. 15: 34. PMID 25260758 DOI: 10.1186/1471-2121-15-34  0.088
2016 Alvero AB, Heaton A, Lima E, Pitruzzello M, Sumi N, Yang-Hartwich Y, Cardenas C, Steinmacher S, Silasi DA, Brown D, Mor G. TRX-E-002-1 induces c-jun-dependent apoptosis in ovarian cancer stem cells and prevents recurrence in vivo. Molecular Cancer Therapeutics. PMID 27196760 DOI: 10.1158/1535-7163.MCT-16-0005  0.088
2005 Shogomori H, Hammond AT, Ostermeyer-Fay AG, Barr DJ, Feigenson GW, London E, Brown DA. Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells. The Journal of Biological Chemistry. 280: 18931-42. PMID 15753089 DOI: 10.1074/Jbc.M500247200  0.088
2018 Stevenson AJ, Ager EI, Proctor MA, Škalamera D, Heaton A, Brown D, Gabrielli BG. Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo. Scientific Reports. 8: 5144. PMID 29572477 DOI: 10.1038/s41598-018-22882-w  0.088
2020 Zhou S, Feng S, Brown D, Huang B. Improved yellow-green split fluorescent proteins for protein labeling and signal amplification. Plos One. 15: e0242592. PMID 33227014 DOI: 10.1371/journal.pone.0242592  0.088
2018 Brown D, Ryan K, Daniel Z, Mareko M, Talbot R, Moreton J, Giles TCB, Emes R, Hodgman C, Parr T, Brameld JM. The Beta-adrenergic agonist, Ractopamine, increases skeletal muscle expression of Asparagine Synthetase as part of an integrated stress response gene program. Scientific Reports. 8: 15915. PMID 30374102 DOI: 10.1038/S41598-018-34315-9  0.088
2019 Pollak TA, Lennox BR, Müller S, Benros ME, Prüss H, Tebartz van Elst L, Klein H, Steiner J, Frodl T, Bogerts B, Tian L, Groc L, Hasan A, Baune BT, Endres D, ... ... Brown DA, et al. Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin. The Lancet. Psychiatry. PMID 31669058 DOI: 10.1016/S2215-0366(19)30290-1  0.088
2012 Mahoney S, Arfuso F, Rogers P, Hisheh S, Brown D, Millward M, Dharmarajan A. Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines. Journal of Biosciences. 37: 73-84. PMID 22357205  0.088
2008 Birla R, Dhawan V, Huang Y, Lytle IF, Tiranathanagul K, Brown D. Force characteristics of in vivo tissue-engineered myocardial constructs using varying cell seeding densities Artificial Organs. 32: 684-691. PMID 18684210 DOI: 10.1111/J.1525-1594.2008.00591.X  0.088
2004 Yang H, Filipovic Z, Brown D, Breit SN, Vassilev LT. Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation. Molecular Cancer Therapeutics. 2: 1023-9. PMID 14578467  0.087
2007 Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. American Journal of Physiology. Heart and Circulatory Physiology. 293: H246-59. PMID 17337597 DOI: 10.1152/Ajpheart.00734.2006  0.087
2015 Fisher OM, Levert-Mignon AJ, Lord SJ, Lee-Ng KK, Botelho NK, Falkenback D, Thomas ML, Bobryshev YV, Whiteman DC, Brown DA, Breit SN, Lord RV. MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma. British Journal of Cancer. 112: 1384-91. PMID 25867265 DOI: 10.1038/Bjc.2015.100  0.087
2005 Kahya N, Brown DA, Schwille P. Raft partitioning and dynamic behavior of human placental alkaline phosphatase in giant unilamellar vesicles. Biochemistry. 44: 7479-89. PMID 15895991 DOI: 10.1021/Bi047429D  0.087
2016 Pennington ER, Fix A, Madison Sullivan E, Brown DA, Kennedy A, Shaikh SR. Distinct membrane properties are differentially influenced by cardiolipin content and acyl chain composition in biomimetic membranes. Biochimica Et Biophysica Acta. PMID 27889304 DOI: 10.1016/J.Bbamem.2016.11.012  0.087
2009 Zhao L, Lee BY, Brown DA, Molloy MP, Marx GM, Pavlakis N, Boyer MJ, Stockler MR, Kaplan W, Breit SN, Sutherland RL, Henshall SM, Horvath LG. Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling. Cancer Research. 69: 7696-703. PMID 19773444 DOI: 10.1158/0008-5472.Can-08-4901  0.086
2003 Tullett J, Rutter P, Brown D. A longitudinal study of United Kingdom pharmacists' misdemeanours--trials, tribulations and trends. Pharmacy World & Science : Pws. 25: 43-51. PMID 12774563 DOI: 10.1023/a:1023288712923  0.086
2017 Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. The Journal of Biological Chemistry. PMID 29162722 DOI: 10.1074/Jbc.M117.812834  0.086
2011 Alvero AB, Montagna MK, Holmberg JC, Craveiro V, Brown D, Mor G. Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells Molecular Cancer Therapeutics. 10: 1385-1393. PMID 21677151 DOI: 10.1158/1535-7163.Mct-11-0023  0.086
2008 Brown DA, MacLellan WR, Dunn JC, Wu BM, Beygui RE. Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 36: 94-113. PMID 18437587 DOI: 10.1080/10731190801932090  0.086
2005 Brown DA, Beygui RE, MacLellan WR, Laks H, Dunn JC, Wu BM. Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates. Journal of Biomedical Materials Research. Part A. 74: 419-29. PMID 15973694 DOI: 10.1002/jbm.a.30344  0.085
2016 Skerratt SE, Andrews MD, Bagal SK, Bilsland J, Brown D, Bungay PJ, Cole S, Gibson KR, Jones R, Morao I, Nedderman A, Omoto K, Robinson C, Ryckmans T, Skinner K, et al. The Discovery of a Potent, Selective and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain. Journal of Medicinal Chemistry. PMID 27766865 DOI: 10.1021/Acs.Jmedchem.6B00850  0.085
2003 Shearer MC, Niclou SP, Brown D, Asher RA, Holtmaat AJ, Levine JM, Verhaagen J, Fawcett JW. The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways. Molecular and Cellular Neurosciences. 24: 913-25. PMID 14697658 DOI: 10.1016/J.Mcn.2003.09.004  0.084
2006 Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circulation Research. 98: 342-50. PMID 16397142 DOI: 10.1161/01.Res.0000202804.84885.D0  0.084
2014 Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. Journal of Cardiovascular Pharmacology and Therapeutics. 19: 121-32. PMID 24288396 DOI: 10.1177/1074248413508003  0.084
2018 Goswami I, Perry JB, Allen ME, Brown DA, von Spakovsky MR, Verbridge SS. Influence of Pulsed Electric Fields and Mitochondria-Cytoskeleton Interactions on Cell Respiration. Biophysical Journal. 114: 2951-2964. PMID 29925031 DOI: 10.1016/J.Bpj.2018.04.047  0.084
2007 Listenberger LL, Ostermeyer-Fay AG, Goldberg EB, Brown WJ, Brown DA. Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnover. Journal of Lipid Research. 48: 2751-61. PMID 17872589 DOI: 10.1194/jlr.M700359-JLR200  0.084
2021 Tea F, Ospina Stella A, Aggarwal A, Ross Darley D, Pilli D, Vitale D, Merheb V, Lee FXZ, Cunningham P, Walker GJ, Fichter C, Brown DA, Rawlinson WD, Isaacs SR, Mathivanan V, et al. SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants. Plos Medicine. 18: e1003656. PMID 34228725 DOI: 10.1371/journal.pmed.1003656  0.083
2007 Gumbo T, Louie A, Liu W, Brown D, Ambrose PG, Bhavnani SM, Drusano GL. Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations. Antimicrobial Agents and Chemotherapy. 51: 2329-36. PMID 17438043 DOI: 10.1128/Aac.00185-07  0.083
2024 Chadwick W, Angulo-Herrera I, Cogram P, Deacon RJM, Mason DJ, Brown D, Roberts I, O'Donovan DJ, Tranfaglia MR, Guilliams T, Thompson NT. A novel combination treatment for fragile X syndrome predicted using computational methods. Brain Communications. 6: fcad353. PMID 38226317 DOI: 10.1093/braincomms/fcad353  0.083
2017 Currier MA, Stehn JR, Swain A, Chen D, Hook J, Eiffe E, Heaton A, Brown D, Nartker B, Eaves DW, Kloss N, Treutlein H, Zeng J, Alieva IB, Dugina VB, et al. Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy With Microtubule Drugs. Molecular Cancer Therapeutics. PMID 28522589 DOI: 10.1158/1535-7163.MCT-16-0873  0.083
2009 Czaplewski LG, Collins I, Boyd EA, Brown D, East SP, Gardiner M, Fletcher R, Haydon DJ, Henstock V, Ingram P, Jones C, Noula C, Kennison L, Rockley C, Rose V, et al. Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ Bioorganic and Medicinal Chemistry Letters. 19: 524-527. PMID 19064318 DOI: 10.1016/J.Bmcl.2008.11.021  0.083
2003 Swarbreck D, Ripoll PJ, Brown DA, Edwards KJ, Theodoulou F. Isolation and characterisation of two multidrug resistance associated protein genes from maize. Gene. 315: 153-64. PMID 14557075 DOI: 10.1016/S0378-1119(03)00734-0  0.082
2019 Leung S, Fiorotti C, Bibik M, Brown D, Gleeson MA, Gorovits B. Multiplexed immunoassay approach to characterize antidrug antibody like specific reactivity. Bioanalysis. PMID 30994012 DOI: 10.4155/bio-2018-0072  0.082
2008 Kirkham M, Nixon SJ, Howes MT, Abi-Rached L, Wakeham DE, Hanzal-Bayer M, Ferguson C, Hill MM, Fernandez-Rojo M, Brown DA, Hancock JF, Brodsky FM, Parton RG. Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science. 121: 2075-86. PMID 18505796 DOI: 10.1242/Jcs.024588  0.082
2010 Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. The Journal of Biological Chemistry. 285: 2796-806. PMID 19926788 DOI: 10.1074/Jbc.M109.058461  0.082
2011 Brown D, Wightman R, Zhang Z, Gomez LD, Atanassov I, Bukowski JP, Tryfona T, McQueen-Mason SJ, Dupree P, Turner S. Arabidopsis genes IRREGULAR XYLEM (IRX15) and IRX15L encode DUF579-containing proteins that are essential for normal xylan deposition in the secondary cell wall Plant Journal. 66: 401-413. PMID 21251108 DOI: 10.1111/J.1365-313X.2011.04501.X  0.081
1981 Brown DA. Electrophysiological effects of nicotine Journal of the Neurological Sciences. 49: 332-333. DOI: 10.1016/0022-510X(81)90091-5  0.08
2003 Kraus E, Galvin JW, Boumakis S, Boamah EK, Canning MT, Yarosh DB, Brown DA. Effects of a melanogenic bicyclic monoterpene diol on cell cycle, p53, TNF-alpha, and PGE2 are distinct from those of UVB. Photodermatology, Photoimmunology & Photomedicine. 19: 295-302. PMID 14617104 DOI: 10.1046/J.1600-0781.2003.00061.X  0.079
2007 Gumbo T, Louie A, Liu W, Ambrose PG, Bhavnani SM, Brown D, Drusano GL. Isoniazid's bactericidal activity ceases because of the emergence of resistance, not depletion of Mycobacterium tuberculosis in the log phase of growth. The Journal of Infectious Diseases. 195: 194-201. PMID 17191164 DOI: 10.1086/510247  0.079
2007 Chan C, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chung CW, Convery MA, Hamblin JN, Johnstone L, Kelly HA, Kleanthous S, Patikis A, Patel C, Pateman AJ, et al. Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides. Journal of Medicinal Chemistry. 50: 1546-57. PMID 17338508 DOI: 10.1021/jm060870c  0.079
2010 Haydon DJ, Bennett JM, Brown D, Collins I, Galbraith G, Lancett P, Macdonald R, Stokes NR, Chauhan PK, Sutariya JK, Nayal N, Srivastava A, Beanland J, Hall R, Henstock V, et al. Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties. Journal of Medicinal Chemistry. 53: 3927-36. PMID 20426423 DOI: 10.1021/Jm9016366  0.078
2020 Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR. The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Communications Biology. 3: 389. PMID 32680996 DOI: 10.1038/s42003-020-1101-3  0.078
2018 Boyles MSP, Brown D, Knox J, Horobin M, Miller MR, Johnston HJ, Stone V. Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools. Inhalation Toxicology. 1-18. PMID 30328741 DOI: 10.1080/08958378.2018.1513610  0.078
2012 Deery E, Schroeder S, Lawrence AD, Taylor SL, Seyedarabi A, Waterman J, Wilson KS, Brown D, Geeves MA, Howard MJ, Pickersgill RW, Warren MJ. An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis. Nature Chemical Biology. 8: 933-40. PMID 23042036 DOI: 10.1038/Nchembio.1086  0.078
1973 Young JA, Brown DA, Kelly JS, Schon F. Autoradiographic localization of sites of (3H)gamma-aminobutyric acid accumulation in peripheral autonomic ganglia. Brain Research. 63: 479-86. PMID 4587480 DOI: 10.1016/0006-8993(73)90128-5  0.077
2015 Shaikh SR, Wassall SR, Brown DA, Kosaraju R. N-3 Polyunsaturated Fatty Acids, Lipid Microclusters, and Vitamin E. Current Topics in Membranes. 75: 209-31. PMID 26015284 DOI: 10.1016/Bs.Ctm.2015.03.003  0.077
2012 Johnston H, Brown D, Kermanizadeh A, Gubbins E, Stone V. Investigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applications. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 307-13. PMID 22940205 DOI: 10.1016/j.jconrel.2012.08.018  0.077
2018 Sullivan EM, Pennington ER, Green WD, Beck MA, Brown DA, Shaikh SR. Mechanisms by Which Dietary Fatty Acids Regulate Mitochondrial Structure-Function in Health and Disease. Advances in Nutrition (Bethesda, Md.). 9: 247-262. PMID 29767698 DOI: 10.1093/Advances/Nmy007  0.077
2009 Alvero AB, Montagna MK, Chen R, Kim KH, Kyungjin K, Visintin I, Fu HH, Brown D, Mor G. NV-128, a novel isoflavone derivative, induces caspase-independent cell death through the Akt/mammalian target of rapamycin pathway. Cancer. 115: 3204-16. PMID 19472400 DOI: 10.1002/Cncr.24397  0.077
2011 Korostenskaja M, Pardos M, Kujala T, Rose DF, Brown D, Horn P, Wang Y, Fujiwara H, Xiang J, Kabbouche MA, Powers SW, Hershey AD. Impaired auditory information processing during acute migraine: a magnetoencephalography study. The International Journal of Neuroscience. 121: 355-65. PMID 21425948 DOI: 10.3109/00207454.2011.560312  0.077
2023 Shen S, Ma W, Brown D, Da Cruz Paula A, Zhou Q, Iaosonos A, Tessier-Cloutier B, Ross DS, Troso-Sandoval T, Reis-Filho JS, Abu-Rustum N, Zhang Y, Ellenson LH, Weigelt B, Makker V, et al. HER2 genetic intratumor heterogeneity is associated with resistance to trastuzumab and trastuzumab emtansine therapy in recurrent high-grade endometrial cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100299. PMID 37558129 DOI: 10.1016/j.modpat.2023.100299  0.076
2006 Brown DA, Canning MT, Nay SL, Pena AV, Yarosh DB. Bicyclic monoterpene diols stimulate release of nitric oxide from skin cells, increase microcirculation, and elevate skin temperature. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 15: 70-6. PMID 16626981 DOI: 10.1016/J.Niox.2006.03.002  0.076
2007 Greer RM, Shah J, Jeske YW, Brown D, Walker RM, Cowley D, Bowling FG, Liaskou D, Harris M, Thomsett MJ, Choong C, Bell JR, Jack MM, Cotterill AM. Genotype-phenotype associations in patients with severe hyperinsulinism of infancy. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 10: 25-34. PMID 17378627 DOI: 10.2350/06-04-0083.1  0.076
2022 Lyster H, Pitt T, Maunz O, Diamond S, Roberts JA, Brown D, Mills J, Armstrong-James D, Gerovasili V, Carby M, Dunning J, Simon A, Reed A. Variable Sequestration of Antifungals in an Extracorporeal Membrane Oxygenation Circuit. Asaio Journal (American Society For Artificial Internal Organs : 1992). PMID 36731055 DOI: 10.1097/MAT.0000000000001802  0.076
2017 Holland NA, Fraiser CR, Sloan RC, Devlin RB, Brown DA, Wingard CJ. Ultrafine Particulate Matter Increases Cardiac Ischemia/Reperfusion Injury via Mitochondrial Permeability Transition Pore. Cardiovascular Toxicology. PMID 28194639 DOI: 10.1007/s12012-017-9402-6  0.076
2010 Prieto-Echagüe V, Gucwa A, Brown DA, Miller WT. Regulation of Ack1 localization and activity by the amino-terminal SAM domain. Bmc Biochemistry. 11: 42. PMID 20979614 DOI: 10.1186/1471-2091-11-42  0.076
2004 Rogers LM, Brown DA, Gruben KG. Foot force direction control during leg pushes against fixed and moving pedals in persons post-stroke. Gait & Posture. 19: 58-68. PMID 14741304 DOI: 10.1016/S0966-6362(03)00009-2  0.076
2021 Makhija S, Brown D, Rudlaff RM, Doh JK, Bourke S, Wang Y, Zhou S, Cheloor-Kovilakam R, Huang B. Versatile Labeling and Detection of Endogenous Proteins Using Tag-Assisted Split Enzyme Complementation. Acs Chemical Biology. PMID 33734687 DOI: 10.1021/acschembio.0c00925  0.076
2010 Wang JL, Carter J, Kiefer JR, Kurumbail RG, Pawlitz JL, Brown D, Hartmann SJ, Graneto MJ, Seibert K, Talley JJ. The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: the first clinical candidate. Bioorganic & Medicinal Chemistry Letters. 20: 7155-8. PMID 21055613 DOI: 10.1016/j.bmcl.2010.07.053  0.076
2008 Anderson CD, Heydarkhan-Hagvall S, Schenke-Layland K, Yang JQ, Jordan MC, Kim JK, Brown DA, Zuk PA, Laks H, Roos KP, Maclellan WR, Beygui RE. The role of cytoprotective cytokines in cardiac ischemia/reperfusion injury. The Journal of Surgical Research. 148: 164-71. PMID 18067924 DOI: 10.1016/J.Jss.2007.08.005  0.076
2022 Büntgen U, Crivellaro A, Arseneault D, Baillie M, Barclay D, Bernabei M, Bontadi J, Boswijk G, Brown D, Christie DA, Churakova OV, Cook ER, D'Arrigo R, Davi N, Esper J, et al. Global wood anatomical perspective on the onset of the Late Antique Little Ice Age (LALIA) in the mid-6th century CE. Science Bulletin. 67: 2336-2344. PMID 36546223 DOI: 10.1016/j.scib.2022.10.019  0.075
2019 Pennington ER, Funai K, Brown DA, Shaikh SR. The role of cardiolipin concentration and acyl chain composition on mitochondrial inner membrane molecular organization and function. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 30951877 DOI: 10.1016/J.Bbalip.2019.03.012  0.075
2010 Prieto-Echagüe V, Gucwa A, Craddock BP, Brown DA, Miller WT. Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. The Journal of Biological Chemistry. 285: 10605-15. PMID 20110370 DOI: 10.1074/jbc.M109.060459  0.075
2005 Liu JW, Chandra D, Rudd MD, Butler AP, Pallotta V, Brown D, Coffer PJ, Tang DG. Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene. 24: 2020-31. PMID 15674333 DOI: 10.1038/Sj.Onc.1208385  0.075
2011 Featherstone DA, Rota PA, Icenogle J, Mulders MN, Jee Y, Ahmed H, de Filippis AM, Ramamurty N, Gavrilin E, Byabamazima C, Dosseh A, Xu W, Komase K, Tashiro M, Brown D, et al. Expansion of the global measles and rubella laboratory network 2005-09. The Journal of Infectious Diseases. 204: S491-8. PMID 21666205 DOI: 10.1093/Infdis/Jir107  0.075
2004 Ren X, Ostermeyer AG, Ramcharan LT, Zeng Y, Lublin DM, Brown DA. Conformational defects slow Golgi exit, block oligomerization, and reduce raft affinity of caveolin-1 mutant proteins. Molecular Biology of the Cell. 15: 4556-67. PMID 15304521 DOI: 10.1091/mbc.E04-06-0480  0.074
2013 Teague H, Rockett BD, Harris M, Brown DA, Shaikh SR. Dendritic cell activation, phagocytosis and CD69 expression on cognate T cells are suppressed by n-3 long-chain polyunsaturated fatty acids. Immunology. 139: 386-94. PMID 23373457 DOI: 10.1111/Imm.12088  0.074
2006 Brown DA. Lipid rafts, detergent-resistant membranes, and raft targeting signals. Physiology (Bethesda, Md.). 21: 430-9. PMID 17119156 DOI: 10.1152/physiol.00032.2006  0.074
2013 Raza Shaikh S, Brown DA. Models of plasma membrane organization can be applied to mitochondrial membranes to target human health and disease with polyunsaturated fatty acids. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 88: 21-5. PMID 22464052 DOI: 10.1016/J.Plefa.2012.03.004  0.074
2021 Delaney LJ, Eisenbrey JR, Brown D, Brody JR, Jimbo M, Oeffinger BE, Stanczak M, Forsberg F, Liu JB, Wheatley MA. Gemcitabine-loaded Microbubble System for Ultrasound Imaging and Therapy. Acta Biomaterialia. PMID 34082100 DOI: 10.1016/j.actbio.2021.05.046  0.073
2019 Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA. Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury. Journal of Molecular and Cellular Cardiology. PMID 31445917 DOI: 10.1016/J.Yjmcc.2019.08.010  0.073
2008 Abbott B, Abbott R, Adhikari R, Ajith P, Allen B, Allen G, Amin R, Anderson SB, Anderson WG, Arain MA, Araya M, Armandula H, Armor P, Aso Y, Aston S, ... Brown DA, et al. Search for gravitational-wave bursts from soft gamma repeaters. Physical Review Letters. 101: 211102. PMID 19113401 DOI: 10.1103/Physrevlett.101.211102  0.073
2008 Lyon DY, Brown DA, Alvarez PJ. Implications and potential applications of bactericidal fullerene water suspensions: effect of nC(60) concentration, exposure conditions and shelf life. Water Science and Technology : a Journal of the International Association On Water Pollution Research. 57: 1533-8. PMID 18520009 DOI: 10.2166/Wst.2008.282  0.073
2019 Tea F, Lopez JA, Ramanathan S, Merheb V, Lee FXZ, Zou A, Pilli D, Patrick E, van der Walt A, Monif M, Tantsis EM, Yiu EM, Vucic S, Henderson APD, Fok A, ... ... Brown DA, et al. Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination. Acta Neuropathologica Communications. 7: 145. PMID 31481127 DOI: 10.1186/S40478-019-0786-3  0.072
2017 Dell'Anna ML, Ottaviani M, Kovacs D, Mirabilii S, Brown DA, Cota C, Migliano E, Bastonini E, Bellei B, Cardinali G, Ricciardi MR, Tafuri A, Picardo M. Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin. Scientific Reports. 7: 13663. PMID 29057950 DOI: 10.1038/s41598-017-13961-5  0.072
2013 Bastian ND, Brown D, Fulton LV, Mitchell R, Pollard W, Robinson M, Wilson R. Analyzing the future of army aeromedical evacuation units and equipment: a mixed methods, requirements-based approach. Military Medicine. 178: 321-9. PMID 23707120 DOI: 10.7205/MILMED-D-12-00370  0.072
2018 Pennington ER, Sullivan EM, Fix A, Dadoo S, Zeczycki TN, DeSantis A, Schlattner U, Coleman RA, Chicco AJ, Brown DA, Shaikh SR. Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. The Journal of Biological Chemistry. PMID 30158245 DOI: 10.1074/Jbc.Ra118.004948  0.071
2007 Young RJ, Brown D, Burns-Kurtis CL, Chan C, Convery MA, Hubbard JA, Kelly HA, Pateman AJ, Patikis A, Senger S, Shah GP, Toomey JR, Watson NS, Zhou P. Selective and dual action orally active inhibitors of thrombin and factor Xa Bioorganic and Medicinal Chemistry Letters. 17: 2927-2930. PMID 17420122 DOI: 10.1016/j.bmcl.2007.03.080  0.071
2001 Brown DA, Jacobson K. Microdomains, lipid rafts and caveolae (San Feliu de Guixols, Spain, 19-24 May 2001). Traffic (Copenhagen, Denmark). 2: 668-72. PMID 11555420 DOI: 10.1034/J.1600-0854.2001.20909.X  0.071
2022 Strillacci A, Sansone P, Rajasekhar VK, Turkekul M, Boyko V, Meng F, Houck-Loomis B, Brown D, Berger MF, Hendrickson RC, Chang Q, de Stanchina E, Pareja F, Reis-Filho JS, Rajappachetty RS, et al. ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance. Npj Breast Cancer. 8: 96. PMID 35999225 DOI: 10.1038/s41523-022-00470-6  0.071
2015 Tsai VW, Lin S, Brown DA, Salis A, Breit SN. Anorexia-cachexia and obesity treatment may be two sides of the same coin: Role of the TGF-b superfamily cytokine MIC-1/GDF15. International Journal of Obesity (2005). PMID 26620888 DOI: 10.1038/Ijo.2015.242  0.071
2012 Mohammad MG, Hassanpour M, Tsai VW, Li H, Ruitenberg MJ, Booth DW, Serrats J, Hart PH, Symonds GP, Sawchenko PE, Breit SN, Brown DA. Dendritic cells and multiple sclerosis: disease, tolerance and therapy. International Journal of Molecular Sciences. 14: 547-62. PMID 23271370 DOI: 10.3390/Ijms14010547  0.071
2011 Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM. Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. Bioorganic & Medicinal Chemistry Letters. 21: 3037-40. PMID 21482467 DOI: 10.1016/j.bmcl.2011.03.038  0.071
2014 Shaikh SR, Sullivan EM, Alleman RJ, Brown DA, Zeczycki TN. Increasing mitochondrial membrane phospholipid content lowers the enzymatic activity of electron transport complexes. Biochemistry. 53: 5589-91. PMID 25145682 DOI: 10.1021/Bi500868G  0.071
2003 Gray JP, Leas TL, Obert E, Brown D, Clark GC, Vanden Heuvel JP. Evidence of aryl hydrocarbon receptor ligands in Presque Isle Bay of Lake Erie. Aquatic Toxicology (Amsterdam, Netherlands). 64: 343-58. PMID 12842597  0.07
2023 Zheng Y, Schroeder S, Kanev GK, Botros SS, William S, Sabra AA, Maes L, Caljon G, Gil C, Martinez A, Salado IG, Augustyns K, Edink E, Sijm M, de Heuvel E, ... ... Brown D, et al. To Target or Not to Target Cyclic Nucleotide Phosphodiesterase 4A? International Journal of Molecular Sciences. 24. PMID 37047792 DOI: 10.3390/ijms24076817  0.07
2011 Rogers LM, Brown DA, Stinear JW. The effects of paired associative stimulation on knee extensor motor excitability of individuals post-stroke: a pilot study. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 122: 1211-8. PMID 21130032 DOI: 10.1016/J.Clinph.2010.11.006  0.07
2020 Pande V, Sun W, Beke L, Berthelot D, Brehmer D, Brown D, Corbera J, Irving S, Meerpoel L, Nys T, Parade M, Robinson C, Sommen C, Viellevoye M, Wu T, et al. A Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode. Acs Medicinal Chemistry Letters. 11: 2227-2231. PMID 33214833 DOI: 10.1021/acsmedchemlett.0c00355  0.07
2020 Breit SN, Brown DA, Tsai VW. The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe? Annual Review of Physiology. PMID 33228454 DOI: 10.1146/annurev-physiol-022020-045449  0.07
2020 Dobreva T, Brown D, Park JH, Thomson M. Single cell profiling of capillary blood enables out of clinic human immunity studies. Scientific Reports. 10: 20540. PMID 33239690 DOI: 10.1038/s41598-020-77073-3  0.07
2021 Curley LJ, Murray J, MacLean R, Munro J, Lages M, Frumkin LA, Laybourn P, Brown D. Verdict spotting: investigating the effects of juror bias, evidence anchors and verdict system in jurors. Psychiatry, Psychology, and Law : An Interdisciplinary Journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law. 29: 323-344. PMID 35898612 DOI: 10.1080/13218719.2021.1904450  0.069
1996 Brougham DF, Barrie PJ, Hawkes GE, Abrahams I, Motevalli M, Brown DA, Long GJ. Solid State Dynamics of Tricarbonyl(eta-1,5-cyclohexadienylium)iron Tetrafluoroborate and Tricarbonyl(eta-1,5-cycloheptadienylium)iron Tetrafluoroborate. Inorganic Chemistry. 35: 5595-5602. PMID 11666751 DOI: 10.1021/Ic951573T  0.069
2016 Neyertz S, Brown D, Raaijmakers MJ, Benes NE. The influence of the dianhydride precursor in hyper-cross-linked hybrid polyPOSS-imide networks. Physical Chemistry Chemical Physics : Pccp. PMID 27713943 DOI: 10.1039/c6cp06184b  0.069
2005 Yarosh DB, Pena AV, Nay SL, Canning MT, Brown DA. Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation. The Journal of Investigative Dermatology. 125: 1020-5. PMID 16297204 DOI: 10.1111/J.0022-202X.2005.23858.X  0.069
2010 Kleanthous S, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chan C, Clarte MO, Convery MA, Harling JD, Hortense E, Irving WR, Irvine S, Pateman AJ, Patikis AN, et al. Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs. Bioorganic & Medicinal Chemistry Letters. 20: 618-22. PMID 20006499 DOI: 10.1016/j.bmcl.2009.11.077  0.069
2023 Wachter S, Angevin T, Bubna N, Tan A, Cichy A, Brown D, Wolfe LS, Sappington R, Lilla E, Berry L, Grismer D, Orth C, Blanusa M, Mostafa S, Kaufmann H, et al. Application of platform process development approaches to the manufacturing of Mabcalin™ bispecifics. Journal of Biotechnology. 377: 13-22. PMID 37820750 DOI: 10.1016/j.jbiotec.2023.10.003  0.069
2003 Jurczyluk J, Brown D, Stanley KK. Polarised secretion of cytokines in primary human microvascular endothelial cells is not dependent on N-linked glycosylation Cell Biology International. 27: 997-1003. PMID 14642531 DOI: 10.1016/J.Cellbi.2003.09.002  0.069
2013 Brown DA, Fletcher H. Use of mediolateral cervical clamping to control postpartum hemorrhage. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics. 123: 164-5. PMID 23992626 DOI: 10.1016/j.ijgo.2013.06.014  0.069
2003 Canning MT, Brown DA, Yarosh DB. A bicyclic monoterpene diol and UVB stimulate BRCA1 phosphorylation in human keratinocytes. Photochemistry and Photobiology. 77: 46-51. PMID 12856882 DOI: 10.1562/0031-8655(2003)0770046Abmdau2.0.Co2  0.068
2011 Sloan RC, Rosenbaum M, O'Rourke D, Oppelt K, Frasier CR, Waston CA, Allan AG, Brown DA. High doses of ketamine-xylazine anesthesia reduce cardiac ischemia-reperfusion injury in guinea pigs. Journal of the American Association For Laboratory Animal Science : Jaalas. 50: 349-54. PMID 21640030  0.068
2003 Welsh JB, Sapinoso LM, Kern SG, Brown DA, Liu T, Bauskin AR, Ward RL, Hawkins NJ, Quinn DI, Russell PJ, Sutherland RL, Breit SN, Moskaluk CA, Frierson HF, Hampton GM. Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proceedings of the National Academy of Sciences of the United States of America. 100: 3410-5. PMID 12624183 DOI: 10.1073/Pnas.0530278100  0.068
2011 Abernathy ES, Hübschen JM, Muller CP, Jin L, Brown D, Komase K, Mori Y, Xu W, Zhu Z, Siqueira MM, Shulga S, Tikhonova N, Pattamadilok S, Incomserb P, Smit SB, et al. Status of global virologic surveillance for rubella viruses. The Journal of Infectious Diseases. 204: S524-32. PMID 21666209 DOI: 10.1093/Infdis/Jir099  0.068
2007 Brown DA, Brink J, Fang H, Gair JR, Li C, Lovelace G, Mandel I, Thorne KS. Prospects for detection of gravitational waves from intermediate-mass-ratio inspirals. Physical Review Letters. 99: 201102. PMID 18233130 DOI: 10.1103/Physrevlett.99.201102  0.067
2011 Rota PA, Brown K, Mankertz A, Santibanez S, Shulga S, Muller CP, Hübschen JM, Siqueira M, Beirnes J, Ahmed H, Triki H, Al-Busaidy S, Dosseh A, Byabamazima C, Smit S, ... ... Brown D, et al. Global distribution of measles genotypes and measles molecular epidemiology. The Journal of Infectious Diseases. 204: S514-23. PMID 21666208 DOI: 10.1093/Infdis/Jir118  0.067
2018 Curley LJ, MacLean R, Murray J, Laybourn P, Brown D. The bastard verdict and its influence on jurors. Medicine, Science, and the Law. 25802418811740. PMID 30501474 DOI: 10.1177/0025802418811740  0.067
2005 Brown DA, Lynch JM, Armstrong CJ, Caruso NM, Ehlers LB, Johnson MS, Moore RL. Susceptibility of the heart to ischaemia-reperfusion injury and exercise-induced cardioprotection are sex-dependent in the rat. The Journal of Physiology. 564: 619-30. PMID 15718263 DOI: 10.1113/jphysiol.2004.081323  0.067
2023 Foyt D, Brown D, Zhou S, Huang B. HybriSeq: Probe-based Device-free Single-cell RNA Profiling. Biorxiv : the Preprint Server For Biology. PMID 37808850 DOI: 10.1101/2023.09.27.559406  0.067
2007 Johnen H, Lin S, Kuffner T, Brown DA, Tsai VW, Bauskin AR, Wu L, Pankhurst G, Jiang L, Junankar S, Hunter M, Fairlie WD, Lee NJ, Enriquez RF, Baldock PA, et al. Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nature Medicine. 13: 1333-40. PMID 17982462 DOI: 10.1038/Nm1677  0.067
2006 Watson NS, Brown D, Campbell M, Chan C, Chaudry L, Convery MA, Fenwick R, Hamblin JN, Haslam C, Kelly HA, King NP, Kurtis CL, Leach AR, Manchee GR, Mason AM, et al. Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 3784-8. PMID 16697194 DOI: 10.1016/j.bmcl.2006.04.053  0.066
2023 Yu C, Ahmed Z, Frisch JC, Henderson SW, Silva-Feaver M, Arnold K, Brown D, Connors J, Cukierman AJ, D'Ewart JM, Dober BJ, Dusatko JE, Haller G, Herbst R, Hilton GC, et al. SLAC microresonator RF (SMuRF) electronics: A tone-tracking readout system for superconducting microwave resonator arrays. The Review of Scientific Instruments. 94: 014712. PMID 36725567 DOI: 10.1063/5.0125084  0.066
2010 Louie A, Bied A, Fregeau C, Van Scoy B, Brown D, Liu W, Bush K, Queenan AM, Morrow B, Khashab M, Kahn JB, Nicholson S, Kulawy R, Drusano GL. Impact of different carbapenems and regimens of administration on resistance emergence for three isogenic Pseudomonas aeruginosa strains with differing mechanisms of resistance. Antimicrobial Agents and Chemotherapy. 54: 2638-45. PMID 20308371 DOI: 10.1128/AAC.01721-09  0.066
2004 Faragalla J, Bremner J, Brown D, Griffith R, Heaton A. Comparative pharmacophore development for inhibitors of human and rat 5-alpha-reductase. Journal of Molecular Graphics & Modelling. 22: 83-92. PMID 12798393 DOI: 10.1016/S1093-3263(03)00138-4  0.066
2013 Frasier CR, Brown DA, Sloan RC, Hayes B, Stewart LM, Patel HD, Lust RM, Rosenbaum MD. Stage of the estrous cycle does not influence myocardial ischemia-reperfusion injury in rats (Rattus norvegicus). Comparative Medicine. 63: 416-21. PMID 24210018  0.066
2009 Zhang F, Eliassen J, Anderson J, Scheifele P, Brown D. The time course of the amplitude and latency in the auditory late response evoked by repeated tone bursts Journal of the American Academy of Audiology. 20: 239-250. PMID 19927696 DOI: 10.3766/Jaaa.20.4.4  0.066
2009 Brown D, Lostroh CP. Inferring gene expression dynamics from reporter protein levels. Biotechnology Journal. 3: 1437-48. PMID 18956349 DOI: 10.1002/biot.200800133  0.066
2021 Trend S, Leffler J, Jones AP, Cha L, Gorman S, Brown DA, Breit SN, Kermode AG, French MA, Ward NC, Hart PH. Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis. Scientific Reports. 11: 5244. PMID 33664396 DOI: 10.1038/s41598-021-84881-8  0.065
2003 Liberski PP, Sikorska B, Bratosiewicz-Wa̧sik J, Waliś A, Brown P, Brown D. Exuberant cellular reaction of the optic nerves in experimental Creutzfeldt-Jakob disease Acta Neurobiologiae Experimentalis. 63: 309-318. PMID 15053254  0.065
2003 Brown DA, Ward RL, Buckhaults P, Liu T, Romans KE, Hawkins NJ, Bauskin AR, Kinzler KW, Vogelstein B, Breit SN. MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2642-50. PMID 12855642  0.065
2016 Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA. Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00858.2015. PMID 26945082 DOI: 10.1152/Ajpheart.00858.2015  0.065
2015 Van Gompel JJ, Klassen BT, Worrell GA, Lee KH, Shin C, Zhao CZ, Brown DA, Goerss SJ, Kall BA, Stead M. Anterior nuclear deep brain stimulation guided by concordant hippocampal recording. Neurosurgical Focus. 38: E9. PMID 26030709 DOI: 10.3171/2015.3.Focus1541  0.064
2012 Liu C, Kelnar K, Vlassov AV, Brown D, Wang J, Tang DG. Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Research. 72: 3393-404. PMID 22719071 DOI: 10.1158/0008-5472.Can-11-3864  0.064
2009 Spangenburg EE, Brown DA, Johnson MS, Moore RL. Alterations in peroxisome proliferator-activated receptor mRNA expression in skeletal muscle after acute and repeated bouts of exercise. Molecular and Cellular Biochemistry. 332: 225-31. PMID 19588229 DOI: 10.1007/s11010-009-0195-1  0.064
2014 Randall RC, Brown DA. Analysis of feedback control of piezoelectric transducers. The Journal of the Acoustical Society of America. 135: 3425-33. PMID 24907806 DOI: 10.1121/1.4875717  0.064
2011 White MY, Brown DA, Sheng S, Cole RN, O'Rourke B, Van Eyk JE. Parallel proteomics to improve coverage and confidence in the partially annotated Oryctolagus cuniculus mitochondrial proteome. Molecular & Cellular Proteomics : McP. 10: M110.004291. PMID 21036924 DOI: 10.1074/mcp.M110.004291  0.064
2011 Frasier CR, Sloan RC, Bostian PA, Gonzon MD, Kurowicki J, Lopresto SJ, Anderson EJ, Brown DA. Short-term exercise preserves myocardial glutathione and decreases arrhythmias after thiol oxidation and ischemia in isolated rat hearts. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1751-9. PMID 21940849 DOI: 10.1152/japplphysiol.01214.2010  0.063
2014 Daige CL, Wiggins JF, Priddy L, Nelligan-Davis T, Zhao J, Brown D. Systemic delivery of a miR34a mimic as a potential therapeutic for liver cancer. Molecular Cancer Therapeutics. 13: 2352-60. PMID 25053820 DOI: 10.1158/1535-7163.MCT-14-0209  0.063
2023 Shvetcov A, Ruitenberg MJ, Delerue F, Gold WA, Brown DA, Finney CA. The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury. Neuroscience and Biobehavioral Reviews. 146: 105074. PMID 36736846 DOI: 10.1016/j.neubiorev.2023.105074  0.063
2023 Nagai-Singer MA, Woolls MK, Leedy K, Hendricks-Wenger A, Brock RM, Coutermarsh-Ott S, Paul T, Morrison HA, Imran KM, Tupik JD, Fletcher EJ, Brown DA, Allen IC. Cellular Context Dictates the Suppression or Augmentation of Triple-Negative Mammary Tumor Metastasis by NLRX1. Journal of Immunology (Baltimore, Md. : 1950). PMID 37909827 DOI: 10.4049/jimmunol.2200834  0.063
2012 Pean E, Demolis P, Moreau A, Hemmings RJ, O'Connor D, Brown D, Shepard T, Abadie E, Pignatti F. The European Medicines Agency review of cabazitaxel (Jevtana®) for the treatment of hormone-refractory metastatic prostate cancer: summary of the scientific assessment of the committee for medicinal products for human use. The Oncologist. 17: 543-9. PMID 22477727 DOI: 10.1634/theoncologist.2011-0364  0.063
2014 Brown D, Weinberger B, Lewis C, Bonaparte H. Understanding exposure from natural gas drilling puts current air standards to the test. Reviews On Environmental Health. 29: 277-92. PMID 24690938 DOI: 10.1515/Reveh-2014-0002  0.063
2002 Talley LI, Grizzle WE, Waterbor JW, Brown D, Weiss H, Frost AR. Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women. International Journal of Cancer. Journal International Du Cancer. 98: 118-27. PMID 11857395 DOI: 10.1002/Ijc.10171  0.062
2023 Pai JA, Hellmann MD, Sauter JL, Mattar M, Rizvi H, Woo HJ, Shah N, Nguyen EM, Uddin FZ, Quintanal-Villalonga A, Chan JM, Manoj P, Allaj V, Baine MK, Bhanot UK, ... ... Brown D, et al. Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade. Cancer Cell. PMID 37001526 DOI: 10.1016/j.ccell.2023.03.009  0.062
2017 Crawford BM, Shammas RL, Fales AM, Brown DA, Hollenbeck ST, Vo-Dinh T, Devi GR. Photothermal ablation of inflammatory breast cancer tumor emboli using plasmonic gold nanostars. International Journal of Nanomedicine. 12: 6259-6272. PMID 28894365 DOI: 10.2147/Ijn.S141164  0.062
2013 Brown DA, Sabbah HN, Shaikh SR. Mitochondrial inner membrane lipids and proteins as targets for decreasing cardiac ischemia/reperfusion injury. Pharmacology & Therapeutics. 140: 258-66. PMID 23867906 DOI: 10.1016/J.Pharmthera.2013.07.005  0.062
2018 Parnell GP, Schibeci SD, Fewings NL, Afrasiabi A, Law SPL, Samaranayake S, Kh'ng JH, Fong YH, Brown DA, Liddle C, Stewart GJ, Booth DR. The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D. Human Molecular Genetics. PMID 30285234 DOI: 10.1093/Hmg/Ddy324  0.062
2007 Brown DA, Maclellan WR, Wu BM, Beygui RE. Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue. Annals of Biomedical Engineering. 35: 1885-97. PMID 17680364 DOI: 10.1007/s10439-007-9360-4  0.062
2012 Tsai VW, Husaini Y, Manandhar R, Lee-Ng KK, Zhang HP, Harriott K, Jiang L, Lin S, Sainsbury A, Brown DA, Breit SN. Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15. Journal of Cachexia, Sarcopenia and Muscle. 3: 239-43. PMID 22936174 DOI: 10.1007/S13539-012-0082-6  0.062
2001 Brown DA. Skin pigmentation enhancers. Journal of Photochemistry and Photobiology. B, Biology. 63: 148-61. PMID 11684462 DOI: 10.1016/S1011-1344(01)00212-3  0.062
2002 Yarosh DB, Boumakis S, Brown AB, Canning MT, Galvin JW, Both DM, Kraus E, O'Connor A, Brown DA. Measurement of UVB-Induced DNA damage and its consequences in models of immunosuppression. Methods (San Diego, Calif.). 28: 55-62. PMID 12231188 DOI: 10.1016/S1046-2023(02)00209-8  0.062
2016 Kaufman MR, Elkwood AI, Brown D, Cece J, Martins C, Bauer T, Weissler J, Rezzadeh K, Jarrahy R. Long-Term Follow-Up after Phrenic Nerve Reconstruction for Diaphragmatic Paralysis: A Review of 180 Patients. Journal of Reconstructive Microsurgery. PMID 27665114 DOI: 10.1055/s-0036-1588018  0.062
2019 Jiang JX, Fewings N, Dervish S, Fois AF, Duma SR, Silsby M, Bandodkar S, Ramanathan S, Bleasel A, John B, Brown DA, Lin MW. Novel Surrogate Markers of CNS Inflammation in CSF in the Diagnosis of Autoimmune Encephalitis. Frontiers in Neurology. 10: 1390. PMID 32116981 DOI: 10.3389/Fneur.2019.01390  0.061
2011 Young RJ, Adams C, Blows M, Brown D, Burns-Kurtis CL, Chan C, Chaudry L, Convery MA, Davies DE, Exall AM, Foster G, Harling JD, Hortense E, Irvine S, Irving WR, et al. Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs. Bioorganic & Medicinal Chemistry Letters. 21: 1582-7. PMID 21349710 DOI: 10.1016/j.bmcl.2011.01.131  0.061
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