Debra A. Schwinn - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
molecular pharmacology, alpha 1 adrenergic receptors

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Morris DP, Lei B, Longo LD, Bomsztyk K, Schwinn DA, Michelotti GA. Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. Plos One. 10: e0134442. PMID 26244980 DOI: 10.1371/journal.pone.0134442  0.76
2015 Levine AS, Alpern RJ, Andrews NC, Antman K, Balser JR, Berg JM, Davis PB, Fitz JG, Golden RN, Goldman L, Jameson JL, Lee VS, Polonsky KS, Rappley MD, Reece EA, ... ... Schwinn DA, et al. Research in academic medical centers: two threats to sustainable support. Science Translational Medicine. 7: 289fs22. PMID 26019216 DOI: 10.1126/scitranslmed.aac5200  0.76
2015 Shields RK, Pizzimenti MA, Dudley-Javoroski S, Schwinn DA. Fostering interprofessional teamwork in an academic medical center: Near-peer education for students during gross medical anatomy. Anatomical Sciences Education. 8: 331-7. PMID 24888728 DOI: 10.1002/ase.1466  0.76
2015 Gradinaru I, Babaeva E, Schwinn DA, Oganesian A. Alpha1a-adrenoceptor genetic variant triggers vascular smooth muscle cell hyperproliferation and agonist induced hypertrophy via EGFR transactivation pathway Plos One. 10. DOI: 10.1371/journal.pone.0142787  0.76
2014 Schwinn DA. Team-based patient care. Learning the delicate dance. Iowa Medicine : Journal of the Iowa Medical Society. 104: 19. PMID 25174086  0.76
2014 Schwinn DA. Unlocking the great GME bottleneck. Iowa Medicine : Journal of the Iowa Medical Society. 104: 22. PMID 25167620  0.76
2014 Kleine-Brueggeney M, Gradinaru I, Babaeva E, Schwinn DA, Oganesian A. Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways. Cellular Signalling. 26: 1985-97. PMID 24835978 DOI: 10.1016/j.cellsig.2014.05.007  0.76
2013 Schwinn DA. Medicine in Iowa--fields of opportunity. Iowa Medicine : Journal of the Iowa Medical Society. 103: 24. PMID 25211970  0.76
2013 Schwinn DA. Celebrating women in medicine. Iowa Medicine : Journal of the Iowa Medical Society. 103: 16. PMID 25208449  0.76
2013 Lei B, Schwinn DA, Morris DP. Stimulation of α1a adrenergic receptors induces cellular proliferation or antiproliferative hypertrophy dependent solely on agonist concentration. Plos One. 8: e72430. PMID 23991110 DOI: 10.1371/journal.pone.0072430  0.76
2013 Kraft JC, Kim J, Schwinn DA, Landau R. A history of pharmacogenomics related to anesthesiology The Wondrous Story of Anesthesia. 585-596. DOI: 10.1007/978-1-4614-8441-7_44  0.76
2012 Schwinn DA, Mackensen GB, Brown EN. Understanding the TXA seizure connection. The Journal of Clinical Investigation. 122: 4339-41. PMID 23187134 DOI: 10.1172/JCI66724  0.76
2011 Oganesian A, Yarov-Yarovoy V, Parks WC, Schwinn DA. Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway. Proceedings of the National Academy of Sciences of the United States of America. 108: 19796-801. PMID 22089237 DOI: 10.1073/pnas.1116271108  0.76
2011 Schwinn DA. Genetics and patient outcome after cardiac surgery: unravelling translational findings. British Journal of Anaesthesia. 107: 839-41. PMID 22088869 DOI: 10.1093/bja/aer347  0.76
2011 von Homeyer P, Schwinn DA. Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade. Anesthesia and Analgesia. 113: 1305-18. PMID 21965354 DOI: 10.1213/ANE.0b013e31822b887e  0.76
2011 Leff JD, Duran H, Enriquez L, DeRose J, Shore-Lesserson L, Kim JH, Schwinn DA, Podgoreanu MV, Rosenberg H. Case 4-2011: malignant hyperthermia in cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia. 25: 731-5. PMID 21420317 DOI: 10.1053/j.jvca.2011.01.013  0.76
2011 Schwinn DA. 2010 Walter C. Randall lecture in biomedical ethics. Scientific integrity: positive & negative academic/industry relationships. The Physiologist. 54: 1, 3-8. PMID 21384773  0.76
2010 Welsby IJ, Podgoreanu MV, Phillips-Bute B, Morris R, Mathew JP, Smith PK, Newman MF, Schwinn DA, Stafford-Smith M. Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia. 24: 427-33. PMID 20056442 DOI: 10.1053/j.jvca.2009.10.030  0.76
2009 Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS. The United States critical illness and injury trials group: an introduction. The Journal of Trauma. 67: S159-60. PMID 19667851 DOI: 10.1097/TA.0b013e3181ad3473  0.76
2009 Lei B, Morris DP, Smith MP, Schwinn DA. Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation. Cellular Signalling. 21: 1532-9. PMID 19520158 DOI: 10.1016/j.cellsig.2009.06.001  0.76
2009 Turer AT, Stevens RD, Bain JR, Muehlbauer MJ, van der Westhuizen J, Mathew JP, Schwinn DA, Glower DD, Newgard CB, Podgoreanu MV. Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion. Circulation. 119: 1736-46. PMID 19307475 DOI: 10.1161/CIRCULATIONAHA.108.816116  0.76
2009 Body SC, Podgoreanu MV, Schwinn DA. Genomics of Perioperative and Procedural Medicine Genomic and Personalized Medicine, Two-Vol Set. 794-805. DOI: 10.1016/B978-0-12-369420-1.00066-4  0.76
2009 Kim JH, Schwinn DA, Landau R. Reply Canadian Journal of Anesthesia. 56: 468. DOI: 10.1007/s12630-009-9081-2  0.76
2008 Turer AT, Schwinn DA. Understanding the transition to acute illness: the promise of perioperative genomics. Journal of Cardiovascular Translational Research. 1: 171-3. PMID 19287505 DOI: 10.1007/s12265-008-9018-0  0.76
2008 Kim JH, Schwinn DA, Landau R. Pharmacogenomics and perioperative medicine--implications for modern clinical practice. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 55: 799-806. PMID 19050082 DOI: 10.1007/BF03034050  0.76
2008 Phillips-Bute B, Mathew JP, Blumenthal JA, Morris RW, Podgoreanu MV, Smith M, Stafford-Smith M, Grocott HP, Schwinn DA, Newman MF. Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery. Psychosomatic Medicine. 70: 953-9. PMID 19005081 DOI: 10.1097/PSY.0b013e318187aee6  0.76
2008 Schwinn DA, Podgoreanu M. Pharmacogenomics and end-organ susceptibility to injury in the perioperative period. Best Practice & Research. Clinical Anaesthesiology. 22: 23-37. PMID 18494387 DOI: 10.1016/j.bpa.2007.09.005  0.76
2008 Schwinn DA, Roehrborn CG. Alpha1-adrenoceptor subtypes and lower urinary tract symptoms. International Journal of Urology : Official Journal of the Japanese Urological Association. 15: 193-9. PMID 18304211 DOI: 10.1111/j.1442-2042.2007.01956.x  0.76
2008 Body SC, Schwinn DA. Limitations of genetic findings that are not in Hardy-Weinberg equilibrium. Anesthesiology. 108: 338; author reply 33. PMID 18212593 DOI: 10.1097/01.anes.0000300073.84815.8f  0.76
2008 Morris DP, Lei B, Wu YX, Michelotti GA, Schwinn DA. The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits. The Journal of Biological Chemistry. 283: 2973-85. PMID 18048357 DOI: 10.1074/jbc.M705795200  0.76
2007 Stafford-Smith M, Bartz R, Wilson K, Baraniuk JN, Schwinn DA. Alpha-adrenergic mRNA subtype expression in the human nasal turbinate. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 54: 549-55. PMID 17602041 DOI: 10.1007/BF03022319  0.76
2007 Mathew JP, Podgoreanu MV, Grocott HP, White WD, Morris RW, Stafford-Smith M, Mackensen GB, Rinder CS, Blumenthal JA, Schwinn DA, Newman MF. Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery. Journal of the American College of Cardiology. 49: 1934-42. PMID 17498578 DOI: 10.1016/j.jacc.2007.01.080  0.76
2007 Michelotti GA, Brinkley DM, Morris DP, Smith MP, Louie RJ, Schwinn DA. Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1979-93. PMID 17384146 DOI: 10.1096/fj.06-7118com  0.76
2007 Schwinn DA, Afshari NA. Author reply Ophthalmology. 114: 1788-1789. DOI: 10.1016/j.ophtha.2007.06.004  0.76
2006 Schwinn DA, Afshari NA. alpha(1)-Adrenergic receptor antagonists and the iris: new mechanistic insights into floppy iris syndrome. Survey of Ophthalmology. 51: 501-12. PMID 16950249 DOI: 10.1016/j.survophthal.2006.06.011  0.76
2006 Podgoreanu MV, White WD, Morris RW, Mathew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation. 114: I275-81. PMID 16820586 DOI: 10.1161/CIRCULATIONAHA.105.001032  0.76
2006 Schwinn DA, Balser JR. Anesthesiology physician scientists in academic medicine: a wake-up call. Anesthesiology. 104: 170-8. PMID 16394703 DOI: 10.1097/00000542-200601000-00023  0.76
2006 Balser J, Schwinn DA. In reply [7] Anesthesiology. 105: 629-630. DOI: 10.1097/00000542-200609000-00036  0.76
2006 Brzezinski M, Michelotti GA, Schwinn DA. Genomics and proteomics Foundations of Anesthesia. 71-78. DOI: 10.1016/B978-0-323-03707-5.50011-5  0.76
2006 Schwinn DA. Nuts and bolts of genetic studies: Does this stuff actually relate to anesthesiology? Anesthesia and Analgesia. 107-109.  0.76
2005 Schwinn DA, Afshari NA. Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg? Ophthalmology. 112: 2059-60. PMID 16325704 DOI: 10.1016/j.ophtha.2005.06.040  0.76
2005 Podgoreanu MV, Schwinn DA. New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics. Journal of the American College of Cardiology. 46: 1965-77. PMID 16325027 DOI: 10.1016/j.jacc.2005.08.040  0.76
2005 Moretti EW, Morris RW, Podgoreanu M, Schwinn DA, Newman MF, Bennett E, Moulin VG, Mba UU, Laskowitz DT. APOE polymorphism is associated with risk of severe sepsis in surgical patients. Critical Care Medicine. 33: 2521-6. PMID 16276176 DOI: 10.1097/01.CCM.0000186368.96146.FB  0.76
2005 Diaw L, Roth M, Schwinn DA, d'Alelio ME, Green LJ, Tangrea JA. Characteristics of a human prostate stromal cell line related to its use in a stromal-epithelial coculture model for the study of cancer chemoprevention. In Vitro Cellular & Developmental Biology. Animal. 41: 142-8. PMID 16153146 DOI: 10.1290/0412079.1  0.76
2005 Schambra UB, Mackensen GB, Stafford-Smith M, Haines DE, Schwinn DA. Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. Neuroscience. 135: 507-23. PMID 16112482 DOI: 10.1016/j.neuroscience.2005.06.021  0.76
2005 Podgoreanu MV, Michelotti GA, Sato Y, Smith MP, Lin S, Morris RW, Grocott HP, Mathew JP, Schwinn DA. Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes. The Journal of Thoracic and Cardiovascular Surgery. 130: 330-9. PMID 16077395 DOI: 10.1016/j.jtcvs.2004.11.052  0.76
2005 Grocott HP, White WD, Morris RW, Podgoreanu MV, Mathew JP, Nielsen DM, Schwinn DA, Newman MF. Genetic polymorphisms and the risk of stroke after cardiac surgery. Stroke; a Journal of Cerebral Circulation. 36: 1854-8. PMID 16051899 DOI: 10.1161/01.STR.0000177482.23478.dc  0.76
2005 Morris DP, Michelotti GA, Schwinn DA. Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans. The Journal of Biological Chemistry. 280: 31368-77. PMID 16012166 DOI: 10.1074/jbc.M501546200  0.76
2005 Schwinn DA, Podgoreanu M. The new age of medical genomics. British Journal of Anaesthesia. 95: 119-21. PMID 16006656 DOI: 10.1093/bja/aei159  0.76
2005 Lei B, Morris DP, Smith MP, Svetkey LP, Newman MF, Rotter JI, Buchanan TA, Beckstrom-Sternberg SM, Green ED, Schwinn DA. Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function. Naunyn-Schmiedeberg's Archives of Pharmacology. 371: 229-39. PMID 15900517 DOI: 10.1007/s00210-005-1019-9  0.76
2005 Welsby IJ, Podgoreanu MV, Phillips-Bute B, Mathew JP, Smith PK, Newman MF, Schwinn DA, Stafford-Smith M. Genetic factors contribute to bleeding after cardiac surgery. Journal of Thrombosis and Haemostasis : Jth. 3: 1206-12. PMID 15892865 DOI: 10.1111/j.1538-7836.2005.01337.x  0.76
2005 Stafford-Smith M, Podgoreanu M, Swaminathan M, Phillips-Bute B, Mathew JP, Hauser EH, Winn MP, Milano C, Nielsen DM, Smith M, Morris R, Newman MF, Schwinn DA. Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 45: 519-30. PMID 15754274 DOI: 10.1053/j.ajkd.2004.11.021  0.76
2004 Hawrylyshyn KA, Michelotti GA, Cogé F, Guénin SP, Schwinn DA. Update on human alpha1-adrenoceptor subtype signaling and genomic organization. Trends in Pharmacological Sciences. 25: 449-55. PMID 15559245 DOI: 10.1016/j.tips.2004.06.011  0.76
2004 Schwinn DA, Price DT, Narayan P. alpha1-Adrenoceptor subtype selectivity and lower urinary tract symptoms. Mayo Clinic Proceedings. 79: 1423-34. PMID 15544022  0.76
2004 Michelotti GA, Schwinn DA. Mechanistic insights into the role of alpha1adrenergic receptors in lower urinary tract symptoms. Current Urology Reports. 5: 258-66. PMID 15260925  0.76
2004 Morris DP, Price RR, Smith MP, Lei B, Schwinn DA. Cellular trafficking of human alpha1a-adrenergic receptors is continuous and primarily agonist-independent. Molecular Pharmacology. 66: 843-54. PMID 15258254 DOI: 10.1124/mol.104.000430  0.76
2004 Gu B, Reiter JP, Schwinn DA, Smith MP, Korstanje C, Thor KB, Dolber PC. Effects of alpha 1-adrenergic receptor subtype selective antagonists on lower urinary tract function in rats with bladder outlet obstruction. The Journal of Urology. 172: 758-62. PMID 15247777 DOI: 10.1097/01.ju.0000131609.96301.e6  0.76
2004 Podgoreanu MV, Schwinn DA. Genomics and the circulation. British Journal of Anaesthesia. 93: 140-8. PMID 15145823 DOI: 10.1093/bja/aeh168  0.76
2004 Booth JV, Ward EE, Colgan KC, Funk BL, El-Moalem H, Smith MP, Milano C, Smith PK, Newman MF, Schwinn DA. Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery? Anesthesia and Analgesia. 98: 1224-31, table of co. PMID 15105192 DOI: 10.1213/01.ANE.0000112325.66981.03  0.76
2004 Roehrborn CG, Schwinn DA. Alpha1-adrenergic receptors and their inhibitors in lower urinary tract symptoms and benign prostatic hyperplasia. The Journal of Urology. 171: 1029-35. PMID 14767264 DOI: 10.1097/01.ju.0000097026.43866.cc  0.76
2004 Schwinn DA, Duke JB. An update on genetic and perioperative patient management Revista Mexicana De Anestesiologia. 27: S73-S77.  0.76
2004 Schwinn DA, Duke JB. New advances in receptor pharmacology Revista Mexicana De Anestesiologia. 27: S85-S89.  0.76
2003 Mackensen GB, Ti LK, Phillips-Bute BG, Mathew JP, Newman MF, Grocott HP. Cerebral embolization during cardiac surgery: impact of aortic atheroma burden. British Journal of Anaesthesia. 91: 656-61. PMID 14570786 DOI: 10.1093/bja/aeg234  0.76
2003 Geissler HJ, Mehlhorn U, Laine GA, Allen SJ, Booth JV, Schwinn DA. Myocardial protection with esmolol during coronary artery bypass grafting surgery [4] (multiple letters) Anesthesiology. 98: 1024-1025. PMID 12657872 DOI: 10.1097/00000542-200304000-00039  0.76
2003 Mathew JP, Grocott HP, Phillips-Bute B, Stafford-Smith M, Laskowitz DT, Rossignol D, Blumenthal JA, Newman MF, Bennett MJ, Booth JV, Clements FM, De Bruijn N, Grichnik K, Hill SE, Podgoreanu MV, ... ... Schwinn DA, et al. Lower endotoxin immunity predicts increased cognitive dysfunction in elderly patients after cardiac surgery Stroke. 34: 508-513. PMID 12574568 DOI: 10.1161/01.STR.0000053844.09493.58  0.76
2003 Hagen SA, Kondyra AL, Grocott HP, El-Moalem H, Bainbridge D, Mathew JP, Newman MF, Reves JG, Schwinn DA, Kwatra MM. Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells. Anesthesiology. 98: 343-8. PMID 12552191 DOI: 10.1097/00000542-200302000-00012  0.76
2003 Michelotti GA, Bauman MJ, Smith MP, Schwinn DA. Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia. The Journal of Biological Chemistry. 278: 8693-705. PMID 12471020 DOI: 10.1074/jbc.M211986200  0.76
2002 Booth JV, Spahn DR, McRae RL, Chesnut LC, El-Moalem H, Atwell DM, Leone BJ, Schwinn DA. Esmolol improves left ventricular function via enhanced beta-adrenergic receptor signaling in a canine model of coronary revascularization. Anesthesiology. 97: 162-9. PMID 12131118 DOI: 10.1097/00000542-200207000-00023  0.76
2002 Swaminathan M, McCreath BJ, Phillips-Bute BG, Newman MF, Mathew JP, Smith PK, Blumenthal JA, Stafford-Smith M, Grocott HP, Hill SE, Reves JG, Schwinn DA, Warner D, Harris M, Kirchner JL, et al. Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction Anesthesia and Analgesia. 95: 1-8. PMID 12088934 DOI: 10.1097/00000539-200207000-00001  0.76
2002 Amory DW, Grigore A, Amory JK, Gerhardt MA, White WD, Smith PK, Schwinn DA, Reves JG, Newman MF. Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2,575 patients. Journal of Cardiothoracic and Vascular Anesthesia. 16: 270-7. PMID 12073195 DOI: 10.1053/jcan.2002.124132  0.76
2002 Hampel C, Dolber PC, Smith MP, Savic SL, Th roff JW, Thor KB, Schwinn DA. Modulation of bladder alpha1-adrenergic receptor subtype expression by bladder outlet obstruction. The Journal of Urology. 167: 1513-21. PMID 11832780  0.76
2002 Schwinn DA, Booth JV. Genetics infuses new life into human physiology: implications of the human genome project for anesthesiology and perioperative medicine. Anesthesiology. 96: 261-3. PMID 11818753  0.76
2002 Price RR, Morris DP, Biswas G, Smith MP, Schwinn DA. Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants. The Journal of Biological Chemistry. 277: 9570-9. PMID 11781325 DOI: 10.1074/jbc.M111762200  0.76
2002 Grigore AM, Grocott HP, Mathew JP, Phillips-Bute B, Stanley TO, Butler A, Landolfo KP, Reves JG, Blumenthal JA, Newman MF, Clements FM, De Bruijn N, Grichnik K, Hill SE, Hilton AK, ... Schwinn DA, et al. The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery Anesthesia and Analgesia. 94: 4-10. PMID 11772792 DOI: 10.1097/00000539-200201000-00002  0.76
2001 Schwinn DA. The role of alpha1-adrenergic receptor subtypes in lower urinary tract symptoms. Bju International. 88: 27-34; discussion 49. PMID 11589667  0.76
2001 Newman MF, Booth JV, Laskowitz DT, Schwinn DA, Grocott HP, Mathew JP. Genetic predictors of perioperative neurological and cognitive injury and recovery Best Practice and Research: Clinical Anaesthesiology. 15: 247-276. DOI: 10.1053/bean.2001.0155  0.76
2001 Schwinn DA. Potential role of different α1-adrenoceptor antagonists in lower urinary tract symptoms Drugs of Today. 37: 13-16.  0.76
2000 Schwinn DA. Novel role for alpha1-adrenergic receptor subtypes in lower urinary tract symptoms. Bju International. 86: 11-20; discussion 20. PMID 11501613  0.76
2000 Michelotti GA, Price DT, Schwinn DA. Alpha 1-adrenergic receptor regulation: basic science and clinical implications. Pharmacology & Therapeutics. 88: 281-309. PMID 11337028 DOI: 10.1016/S0163-7258(00)00092-9  0.76
2000 Price DT, Rudner X, Michelotti GA, Schwinn DA. Immortalization of a human prostate stromal cell line using a recombinant retroviral approach. The Journal of Urology. 164: 2145-50. PMID 11061945  0.76
2000 Shapiro RE, Winters B, Hales M, Barnett T, Schwinn DA, Flavahan N, Berkowitz DE. Endogenous circulating sympatholytic factor in orthostatic intolerance. Hypertension. 36: 553-60. PMID 11040235  0.76
2000 Kilts JD, Gerhardt MA, Richardson MD, Sreeram G, Mackensen GB, Grocott HP, White WD, Davis RD, Newman MF, Reves JG, Schwinn DA, Kwatra MM. Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i). Circulation Research. 87: 705-9. PMID 11029407  0.76
2000 Schwinn DA, Michelotti GA. alpha1-adrenergic receptors in the lower urinary tract and vascular bed: potential role for the alpha1d subtype in filling symptoms and effects of ageing on vascular expression. Bju International. 85: 6-11. PMID 10781179  0.76
2000 Ongioco RR, Richardson CD, Rudner XL, Stafford-Smith M, Schwinn DA. Alpha2-adrenergic receptors in human dorsal root ganglia: predominance of alpha2b and alpha2c subtype mRNAs. Anesthesiology. 92: 968-76. PMID 10754615  0.76
2000 Smith MS, Schwinn DA. In situ hybridization of adrenergic receptor mRNA in brain. Methods in Molecular Biology (Clifton, N.J.). 126: 519-33. PMID 10685433  0.76
2000 Schwinn DA. Latest results of the research on α1-adrenoceptor subtypes Drugs of Today. 36: 7-9.  0.76
1999 Rudner XL, Berkowitz DE, Booth JV, Funk BL, Cozart KL, D'Amico EB, El-Moalem H, Page SO, Richardson CD, Winters B, Marucci L, Schwinn DA. Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age. Circulation. 100: 2336-43. PMID 10587338  0.76
1999 Goepel M, Krege S, Price DT, Michelotti GA, Schwinn DA, Michel MC. Characterization of alpha-adrenoceptor subtypes in the corpus cavernosum of patients undergoing sex change surgery. The Journal of Urology. 162: 1793-9. PMID 10524937 DOI: 10.1016/S0022-5347(05)68240-7  0.76
1999 Price DT, Della Rocca G, Guo C, Ballo MS, Schwinn DA, Luttrell LM. Activation of extracellular signal-regulated kinase in human prostate cancer. The Journal of Urology. 162: 1537-42. PMID 10492251 DOI: 10.1016/S0022-5347(05)68354-1  0.76
1999 Langer SZ, Kirby R, Wyllie MG, Clarke DE, Andersson KE, Chapple C. Role of alpha1-adrenoceptors in the future treatment of urological diseases. European Urology. 36: 66-7. PMID 10438242 DOI: 10.1159/000052323  0.76
1999 Schwinn DA, Price RR. Molecular pharmacology of human alpha1-adrenergic receptors: unique features of the alpha 1a-subtype. European Urology. 36: 7-10. PMID 10393466  0.76
1999 Smith MS, Schambra UB, Wilson KH, Page SO, Schwinn DA. Alpha1-adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha1-adrenergic receptor subtypes at four distinct levels. Brain Research. Molecular Brain Research. 63: 254-61. PMID 9878769 DOI: 10.1016/S0169-328X(98)00287-3  0.76
1999 Debruyne FMJ, Clarke DE, Rankin, Wyllie MG, Andersson KE, Kirby R, De Groat WC, Schwinn DA. Discussion European Urology. 36: 65. DOI: 10.1159/000052322  0.76
1998 Lee K, Richardson CD, Razik MA, Kwatra MM, Schwinn DA. Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. Dna Sequence : the Journal of Dna Sequencing and Mapping. 8: 271-6. PMID 10520459 DOI: 10.3109/10425179809008464  0.76
1998 Gerhardt MA, Booth JV, Chesnut LC, Funk BL, el-Moalem HE, Kwatra MM, Schwinn DA. Acute myocardial beta-adrenergic receptor dysfunction after cardiopulmonary bypass in patients with cardiac valve disease. Duke Heart Center Perioperative Desensitization Group. Circulation. 98: II275-81. PMID 9852914  0.76
1998 Booth JV, Landolfo KP, Chesnut LC, Bennett-Guerrero E, Gerhardt MA, Atwell DM, El-Moalem HE, Smith MS, Funk BL, Kuhn CM, Kwatra MM, Schwinn DA. Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group. Anesthesiology. 89: 602-11. PMID 9743395 DOI: 10.1097/00000542-199809000-00008  0.76
1998 Malloy BJ, Price DT, Price RR, Bienstock AM, Dole MK, Funk BL, Rudner XL, Richardson CD, Donatucci CF, Schwinn DA. Alpha1-adrenergic receptor subtypes in human detrusor. The Journal of Urology. 160: 937-43. PMID 9720591 DOI: 10.1016/S0022-5347(01)62836-2  0.76
1998 Schwinn DA, DeLong ER, Shafer SL. Writing successful research proposals for medical science. Anesthesiology. 88: 1660-6. PMID 9637661 DOI: 10.1097/00000542-199806000-00031  0.76
1998 Smiley RM, Kwatra MM, Schwinn DA. New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance. Journal of Cardiothoracic and Vascular Anesthesia. 12: 80-95. PMID 9509364 DOI: 10.1016/S1053-0770(98)90062-3  0.76
1998 Scanga DR, Schwinn DA. Transcriptional regulation of alpha-1 adrenergic receptors. Frontiers in Bioscience : a Journal and Virtual Library. 3: d348-53. PMID 9497274  0.76
1998 Nishimura K, Warabi K, Roush ED, Frederick J, Schwinn DA, Kwatra MM. Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes. Biochemistry. 37: 1192-8. PMID 9477943 DOI: 10.1021/bi972302s  0.76
1998 Mathes DD, Bennett-Guerrero E, Schwinn DA. Treatment of myxedema coma for emergency surgery [8] (multiple letters) Anesthesia and Analgesia. 86: 450-451. PMID 9459274 DOI: 10.1097/00000539-199802000-00056  0.76
1998 Schwinn DA, Kwatra MM. Expression and regulation of alpha 1-adrenergic receptors in human tissues. Advances in Pharmacology (San Diego, Calif.). 42: 390-4. PMID 9327922  0.76
1997 Wilson KH, Schambra UB, Smith MS, Page SO, Richardson CD, Fremeau RT, Schwinn DA. In situ hybridization: identification of rare mRNAs in human tissues. Brain Research. Brain Research Protocols. 1: 175-85. PMID 9385082 DOI: 10.1016/S1385-299X(96)00028-1  0.76
1997 Razik MA, Lee K, Price RR, Williams MR, Ongjoco RR, Dole MK, Rudner XL, Kwatra MM, Schwinn DA. Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region. The Journal of Biological Chemistry. 272: 28237-46. PMID 9353275 DOI: 10.1074/jbc.272.45.28237  0.76
1997 Richardson CD, Donatucci CF, Page SO, Wilson KH, Schwinn DA. Pharmacology of tamsulosin: saturation-binding isotherms and competition analysis using cloned alpha 1-adrenergic receptor subtypes. The Prostate. 33: 55-9. PMID 9294627 DOI: 10.1002/(SICI)1097-0045(19970915)33:1<55::AID-PROS9>3.0.CO;2-8  0.76
1997 Bennett-Guerrero E, Kramer DC, Schwinn DA. Effect of chronic and acute thyroid hormone reduction on perioperative outcome. Anesthesia and Analgesia. 85: 30-6. PMID 9212118 DOI: 10.1097/00000539-199707000-00006  0.76
1997 Tan JP, Seidler FJ, Schwinn DA, Page SO, Slotkin TA. A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors. Pediatric Research. 42: 93-102. PMID 9212043 DOI: 10.1203/00006450-199707000-00015  0.76
1997 Kirshbom PM, Page SO, Jacobs MT, Tsui SS, Bello E, Ungerleider RM, Schwinn DA, Gaynor JW. Cardiopulmonary bypass and circulatory arrest increase endothelin-1 production and receptor expression in the lung. The Journal of Thoracic and Cardiovascular Surgery. 113: 777-83. PMID 9104988 DOI: 10.1016/S0022-5223(97)70237-X  0.76
1997 Schwinn DA, Kwatra MM. α1,-Adrenoceptor Subtypes in the Human Cardiovascular and Urogenital Systems Advances in Pharmacology. 42: 390-394. DOI: 10.1016/S1054-3589(08)60771-1  0.76
1997 Kwatra MM, Nishimura K, Warabi K, Roush ED, Schwinn DA. Membrane-bound human substance p receptor undergoes agonist-dependent phosphorylation by g protein receptor kinase 2 (grk2) to a high stoichiometry and activates grk2 in the absence of gβγ Faseb Journal. 11: A1056.  0.76
1996 Bello EA, Schwinn DA. Molecular biology and medicine. A primer for the clinician. Anesthesiology. 85: 1462-78. PMID 8968195 DOI: 10.1097/00000542-199612000-00029  0.76
1996 Lacey JP, Donatucci CF, Price DT, Page SO, Bennett SA, Tenniswood MP, Schwinn DA. Effects of androgen deprivation on prostate alpha 1-adrenergic receptors. Urology. 48: 335-41. PMID 8753753 DOI: 10.1016/S0090-4295(96)00183-5  0.76
1996 Chen B, Leverette RD, Schwinn DA, Kwatra MM. Human G(alpha q): cDNA and tissue distribution. Biochimica Et Biophysica Acta. 1281: 125-8. PMID 8664309 DOI: 10.1016/0005-2736(96)00039-9  0.76
1996 Boylston BF, Bennett-Guerrero E, Schwinn DA. Triiodothyronine and cardiac surgery [3] Journal of the American Medical Association. 276: 100-101. PMID 8656493  0.76
1996 Kirshbom PM, Jacobs MT, Tsui SS, DiBernardo LR, Schwinn DA, Ungerleider RM, Gaynor JW. Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung. The Journal of Thoracic and Cardiovascular Surgery. 111: 1248-56. PMID 8642827 DOI: 10.1016/S0022-5223(96)70228-3  0.76
1996 Berkowitz DE, Richardson C, Elliott DA, Leslie JB, Schwinn DA. Hypotension resistant to therapy with alpha receptor agonists complicating cardiopulmonary bypass: lithium as a potential cause. Anesthesia and Analgesia. 82: 1082-5. PMID 8610874 DOI: 10.1097/00000539-199605000-00038  0.76
1996 Bennett-Guerrero E, Jimenez JL, White WD, D'Amico EB, Baldwin BI, Schwinn DA. Cardiovascular effects of intravenous triiodothyronine in patients undergoing coronary artery bypass graft surgery. A randomized, double-blind, placebo- controlled trial. Duke T3 study group. Jama. 275: 687-92. PMID 8594265 DOI: 10.1001/jama.275.9.687  0.76
1995 Smith MS, Schambra UB, Wilson KH, Page SO, Hulette C, Light AR, Schwinn DA. alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels. Brain Research. Molecular Brain Research. 34: 109-17. PMID 8750866 DOI: 10.1016/0169-328X(95)00148-L  0.76
1995 Kwatra MM, Schreurs J, Schwinn DA, Innis MA, Caron MG, Lefkowitz RJ. Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity. Protein Expression and Purification. 6: 717-21. PMID 8746622 DOI: 10.1006/prep.1995.0001  0.76
1995 Margolis JO, McGrath BJ, Kussin PS, Schwinn DA. Do not resuscitate (DNR) orders during surgery: ethical foundations for institutional policies in the United States. Anesthesia and Analgesia. 80: 806-9. PMID 7893039 DOI: 10.1097/00000539-199504000-00027  0.76
1995 Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman NP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ. Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. The Journal of Pharmacology and Experimental Therapeutics. 272: 134-42. PMID 7815325  0.76
1995 Kirshbom PM, Tsui SS, DiBernardo LR, Meliones JN, Schwinn DA, Ungerleider RM, Gaynor JW. Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest. Surgery. 118: 440-4; discussion 44. PMID 7638762 DOI: 10.1016/S0039-6060(05)80356-3  0.76
1995 Berkowitz DE, Nardone NA, Smiley RM, Price DT, Kreutter DK, Fremeau RT, Schwinn DA. Distribution of beta 3-adrenoceptor mRNA in human tissues. European Journal of Pharmacology. 289: 223-8. PMID 7621895 DOI: 10.1016/0922-4106(95)90098-5  0.76
1995 D'Amico TA, Meyers CH, Koutlas TC, Peterseim DS, Sabiston DC, Van Trigt P, Schwinn DA. Desensitization of myocardial beta-adrenergic receptors and deterioration of left ventricular function after brain death. The Journal of Thoracic and Cardiovascular Surgery. 110: 746-51. PMID 7564442 DOI: 10.1016/S0022-5223(95)70107-9  0.76
1995 Michel MC, Kenny B, Schwinn DA. Classification of alpha 1-adrenoceptor subtypes. Naunyn-Schmiedeberg's Archives of Pharmacology. 352: 1-10. PMID 7477417 DOI: 10.1007/BF00169183  0.76
1994 Price DT, Lefkowitz RJ, Caron MG, Berkowitz D, Schwinn DA. Localization of mRNA for three distinct alpha 1-adrenergic receptor subtypes in human tissues: implications for human alpha-adrenergic physiology. Molecular Pharmacology. 45: 171-5. PMID 8114668  0.76
1994 Price DT, Chari RS, Berkowitz DE, Meyers WC, Schwinn DA. Expression of alpha 1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: implications for alpha 1-adrenergic receptor subtype classification. Molecular Pharmacology. 46: 221-6. PMID 8078485  0.76
1994 Berkowitz DE, Price DT, Bello EA, Page SO, Schwinn DA. Localization of messenger RNA for three distinct alpha 2-adrenergic receptor subtypes in human tissues. Evidence for species heterogeneity and implications for human pharmacology. Anesthesiology. 81: 1235-44. PMID 7978483  0.76
1994 Peterseim DS, Chesnut LC, Meyers CH, D'Amico TA, Van Trigt P, Schwinn DA. Stability of the beta-adrenergic receptor/adenylyl cyclase pathway of pediatric myocardium after brain death. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 13: 635-40. PMID 7947880  0.76
1994 Schwinn DA. Adrenergic receptors: unique localization in human tissues. Advances in Pharmacology (San Diego, Calif.). 31: 333-41. PMID 7532987 DOI: 10.1016/S1054-3589(08)60626-2  0.76
1993 Franiak RJ, Schwinn DA. Acute myelogenous leukemia: implications of acute blast crisis and cardiopulmonary bypass. Journal of Cardiothoracic and Vascular Anesthesia. 7: 455-7. PMID 8400103 DOI: 10.1016/1053-0770(93)90170-P  0.76
1993 Liggett SB, Freedman NJ, Schwinn DA, Lefkowitz RJ. Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 3665-9. PMID 8386380 DOI: 10.1073/pnas.90.8.3665  0.76
1993 Schwinn DA. Adrenoceptors as models for G protein-coupled receptors: structure, function and regulation. British Journal of Anaesthesia. 71: 77-85. PMID 8343342  0.76
1993 Price DT, Schwinn DA, Lomasney JW, Allen LF, Caron MG, Lefkowitz RJ. Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. The Journal of Urology. 150: 546-51. PMID 7686987 DOI: 10.1016/S0022-5347(17)35544-1  0.76
1993 Kwatra MM, Schwinn DA, Schreurs J, Blank JL, Kim CM, Benovic JL, Krause JE, Caron MG, Lefkowitz RJ. The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2. The Journal of Biological Chemistry. 268: 9161-4. PMID 7683643  0.76
1992 Lu CD, Schwinn DA. Management of a difficult intubation during acute myocardial ischemia following a failed angioplasty. Journal of Cardiothoracic and Vascular Anesthesia. 6: 335-7. PMID 1611001 DOI: 10.1016/1053-0770(92)90153-X  0.76
1992 Thomas RF, Holt BD, Schwinn DA, Liggett SB. Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements. Proceedings of the National Academy of Sciences of the United States of America. 89: 4490-4. PMID 1374904 DOI: 10.1073/pnas.89.10.4490  0.76
1992 Hoehe MR, Berrettini WH, Schwinn DA, Hsieh WT. A two-allele PstI RFLP for the alpha-1C adrenergic receptor gene (ADRA1C). Human Molecular Genetics. 1: 349. PMID 1363873  0.76
1992 Schwinn DA, Lomasney JW. Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype. European Journal of Pharmacology. 227: 433-6. PMID 1359975 DOI: 10.1016/0922-4106(92)90162-O  0.76
1992 Scheinin M, Schwinn DA. The locus coeruleus. Site of hypnotic actions of alpha 2-adrenoceptor agonists? Anesthesiology. 76: 873-5. PMID 1350888  0.76
1991 Schwinn DA. Beta-adrenergic receptor function in surgical patients. Anesthesia and Analgesia. 72: 412. PMID 1847279  0.76
1991 Lomasney JW, Cotecchia S, Lorenz W, Leung WY, Schwinn DA, Yang-Feng TL, Brownstein M, Lefkowitz RJ, Caron MG. Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. The Journal of Biological Chemistry. 266: 6365-9. PMID 1706716  0.76
1991 Schwinn DA, Correa-Sales C, Page SO, Maze M. Functional effects of activation of alpha-1 adrenoceptors by dexmedetomidine: in vivo and in vitro studies. The Journal of Pharmacology and Experimental Therapeutics. 259: 1147-52. PMID 1684815  0.76
1991 Liggett SB, Schwinn DA. Multiple potential regulatory elements in the 5' flanking region of the beta 3-adrenergic receptor. Dna Sequence : the Journal of Dna Sequencing and Mapping. 2: 61-3. PMID 1666313 DOI: 10.3109/10425179109008441  0.76
1991 Schwinn DA, Leone BJ, Spahn DR, Chesnut LC, Page SO, McRae RL, Liggett SB. Desensitization of myocardial beta-adrenergic receptors during cardiopulmonary bypass. Evidence for early uncoupling and late downregulation. Circulation. 84: 2559-67. PMID 1659956 DOI: 10.1161/01.CIR.84.6.2559  0.76
1991 Schwinn DA, Page SO, Middleton JP, Lorenz W, Liggett SB, Yamamoto K, Lapetina EG, Caron MG, Lefkowitz RJ, Cotecchia S. The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity. Molecular Pharmacology. 40: 619-26. PMID 1658600  0.76
1990 Schwinn DA. Pro-choice/abortion? Journal of the American Medical Women's Association (1972). 45: 66-7. PMID 2335691  0.76
1990 Schwinn DA, McIntyre RW, Reves JG. Isoflurane-induced vasodilation: role of the alpha-adrenergic nervous system. Anesthesia and Analgesia. 71: 451-9. PMID 1977331  0.76
1990 Schwinn DA, Lomasney JW, Lorenz W, Szklut PJ, Fremeau RT, Yang-Feng TL, Caron MG, Lefkowitz RJ, Cotecchia S. Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. The Journal of Biological Chemistry. 265: 8183-9. PMID 1970822  0.76
1990 Schwinn DA, Cotecchia S, Lorenz W, Caron MG, Lefkowitz RJ. The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family. Transactions of the Association of American Physicians. 103: 112-8. PMID 1966743  0.76
1989 Schwinn DA, Reves JG. Time course and hemodynamic effects of alpha-1-adrenergic bolus administration in anesthetized patients with myocardial disease. Anesthesia and Analgesia. 68: 571-8. PMID 2541637  0.76
1989 McIntyre RW, Schwinn DA. Atrial natriuretic peptide. Journal of Cardiothoracic Anesthesia. 3: 91-8. PMID 2535291 DOI: 10.1016/0888-6296(89)90018-5  0.76
1988 Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7159-63. PMID 2845398 DOI: 10.1073/PNAS.85.19.7159  0.76
1988 Schwinn DA, McIntyre RW, Hawkins ED, Kates RA, Reves JG. alpha 1-Adrenergic responsiveness during coronary artery bypass surgery: effect of preoperative ejection fraction. Anesthesiology. 69: 206-17. PMID 2841891  0.76
1981 Bieber CP, Hunt SA, Schwinn DA, Jamieson SA, Reitz BA, Oyer PE, Shumway NE, Stinson EB. Complications in long-term survivors of cardiac transplantation. Transplantation Proceedings. 13: 207-11. PMID 7022823  0.76
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