Edward Seto - Publications

Affiliations: 
University of South Florida, Tampa, FL, United States 
Area:
Biochemistry

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ling H, Li Y, Peng C, Yang S, Seto E. HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance. Biorxiv : the Preprint Server For Biology. PMID 38106051 DOI: 10.1101/2023.12.05.570182  0.508
2023 Emmons MF, Bennett RL, Riva A, Gupta K, Carvalho LADC, Zhang C, Macaulay R, Dupéré-Richér D, Fang B, Seto E, Koomen JM, Li J, Chen YA, Forsyth PA, Licht JD, et al. HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. Nature Communications. 14: 7759. PMID 38030596 DOI: 10.1038/s41467-023-43519-1  0.345
2023 Ho TT, Peng C, Seto E, Lin H. Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11. Acs Chemical Biology. PMID 36977486 DOI: 10.1021/acschembio.2c00840  0.341
2021 Bahl S, Ling H, Acharige NPN, Santos-Barriopedro I, Pflum MKH, Seto E. EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function. Cell Death & Disease. 12: 469. PMID 33976119 DOI: 10.1038/s41419-021-03697-6  0.497
2021 Chen J, Cheng F, Sahakian E, Powers J, Wang Z, Tao J, Seto E, Pinilla-Ibarz J, Sotomayor EM. HDAC11 regulates expression of C/EBPβ and immunosuppressive molecules in myeloid-derived suppressor cells. Journal of Leukocyte Biology. 109: 891-900. PMID 33866588 DOI: 10.1002/JLB.1A1119-606RRR  0.352
2020 Bahl S, Seto E. Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance. Cellular and Molecular Life Sciences : Cmls. PMID 32683534 DOI: 10.1007/S00018-020-03599-4  0.565
2020 Heim CE, Bosch ME, Yamada KJ, Aldrich AL, Chaudhari SS, Klinkebiel D, Gries CM, Alqarzaee AA, Li Y, Thomas VC, Seto E, Karpf AR, Kielian T. Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection. Nature Microbiology. PMID 32661313 DOI: 10.1038/S41564-020-0756-3  0.319
2020 Li Y, Zhang X, Zhu S, Dejene EA, Peng W, Sepulveda A, Seto E. HDAC10 Regulates Cancer Stem-like Cell Properties in KRAS-driven Lung Adenocarcinoma. Cancer Research. PMID 32540961 DOI: 10.1158/0008-5472.Can-19-3613  0.386
2020 Dejene EA, Li Y, Showkatian Z, Ling H, Seto E. Regulation of poly(A)-specific ribonuclease activity by reversible lysine acetylation. The Journal of Biological Chemistry. PMID 32457045 DOI: 10.1074/Jbc.Ra120.012552  0.437
2019 Santos-Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines interaction with the proteasome receptor ADRM1. Genes & Cancer. 10: 119-133. PMID 31798765 DOI: 10.18632/Genesandcancer.197  0.469
2019 Rahhal R, Seto E. Emerging roles of histone modifications and HDACs in RNA splicing. Nucleic Acids Research. 47: 4911-4926. PMID 31162605 DOI: 10.1093/Nar/Gkz292  0.494
2019 Emmons MF, Faião-Flores F, Sharma R, Thapa R, Messina JL, Becker JC, Schadendorf D, Seto E, Sondak VK, Koomen JM, Chen YA, Lau EK, Wan L, Licht JD, Smalley KSM. HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy. Cancer Research. PMID 30987999 DOI: 10.1158/0008-5472.Can-19-0040  0.493
2019 Urdinguio RG, Lopez V, Bayón GF, Diaz de la Guardia R, Sierra MI, García-Toraño E, Perez RF, García MG, Carella A, Pruneda PC, Prieto C, Dmitrijeva M, Santamarina P, Belmonte T, Mangas C, ... ... Seto E, et al. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment. Nucleic Acids Research. PMID 30923829 DOI: 10.1093/Nar/Gkz195  0.517
2019 Cao J, Sun L, Aramsangtienchai P, Spiegelman NA, Zhang X, Huang W, Seto E, Lin H. HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2. Proceedings of the National Academy of Sciences of the United States of America. PMID 30819897 DOI: 10.1073/Pnas.1815365116  0.526
2019 Hu M, Armstrong N, Seto E, Li W, Zhu F, Wang PC, Tang Q. Sirtuin 6 Attenuates Kaposi's Sarcoma-associated herpesvirus (KSHV) Reactivation via Suppressing the Ori-Lyt Activity and Expression of RTA. Journal of Virology. PMID 30651359 DOI: 10.1128/Jvi.02200-18  0.475
2019 Emmons M, Flores F, Koomen J, Seto E, Messina J, Lau E, Licht J, Smalley K. Abstract 3800: HDAC8 regulates plasticity and escape from therapy in BRAF mutant melanoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3800  0.339
2018 Ling H, Peng L, Wang J, Rahhal R, Seto E. Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication. Cell Reports. 25: 2851-2865.e3. PMID 30517871 DOI: 10.1016/J.Celrep.2018.11.025  0.493
2018 Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, ... Seto E, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. Jci Insight. 3. PMID 30089714 DOI: 10.1172/Jci.Insight.120159  0.355
2018 Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, ... Seto E, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. Jci Insight. 3. PMID 30089714 DOI: 10.1172/Jci.Insight.120159  0.355
2018 Sun L, Marin de Evsikova C, Bian K, Achille A, Telles E, Pei H, Seto E. Programming and Regulation of Metabolic Homeostasis by HDAC11. Ebiomedicine. PMID 29958910 DOI: 10.1016/J.Ebiom.2018.06.025  0.453
2018 Bagchi R, Ferguson B, Stratton M, Hu T, Cavasin M, Lin Y, Song K, Scherer P, Collins S, Seto E, McKinsey T. Epigenetic regulation of cardiometabolic disease by HDAC-BET association Journal of Molecular and Cellular Cardiology. 124: 99. DOI: 10.1016/J.Yjmcc.2018.07.054  0.452
2017 Huang J, Wang L, Dahiya S, Beier UH, Han R, Samanta A, Bergman J, Sotomayor EM, Seto E, Kozikowski AP, Hancock WW. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Scientific Reports. 7: 8626. PMID 28819166 DOI: 10.1038/S41598-017-09211-3  0.42
2017 Sahakian E, Chen J, Powers JJ, Chen X, Maharaj K, Deng SL, Lienlaf M, Wang HW, Cheng F, Sodré AL, Distler A, Xing L, Perez-Villarroel P, Wei S, Villagra A, ... Seto E, et al. Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology. Journal of Leukocyte Biology. PMID 28550123 DOI: 10.1189/Jlb.1A0415-176Rrr  0.526
2017 Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, ... ... Seto E, et al. T-cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model. Blood. PMID 28550044 DOI: 10.1182/Blood-2016-08-731505  0.42
2016 Li Y, Seto E. HDACs and HDAC Inhibitors in Cancer Development and Therapy. Cold Spring Harbor Perspectives in Medicine. PMID 27599530 DOI: 10.1101/Cshperspect.A026831  0.533
2016 Villagra A, Sahakian E, Seto E. Preparation and Biochemical Analysis of Classical Histone Deacetylases. Methods in Enzymology. 573: 161-81. PMID 27372753 DOI: 10.1016/Bs.Mie.2016.04.005  0.488
2016 Luo H, Shenoy AK, Li X, Jin Y, Jin L, Cai Q, Tang M, Liu Y, Chen H, Reisman D, Wu L, Seto E, Qiu Y, Dou Y, Casero RA, et al. MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition. Cell Reports. PMID 27292636 DOI: 10.1016/J.Celrep.2016.05.050  0.487
2016 Sotolongo A, Mónica FZ, Kots A, Xiao H, Liu J, Seto E, Bian K, Murad F. Epigenetic regulation of soluble guanylate cyclase (sGC) β1 in breast cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27279362 DOI: 10.1096/Fj.201600339R  0.476
2016 Lienlaf M, Perez-Villarroel P, Knox T, Pabon M, Sahakian E, Powers J, Woan KV, Lee C, Cheng F, Deng S, Smalley KS, Montecino M, Kozikowski A, Pinilla-Ibarz J, Sarnaik A, ... Seto E, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Molecular Oncology. PMID 26775640 DOI: 10.1016/J.Molonc.2015.12.012  0.453
2016 Chen J, Cheng F, Woods DM, Seto E, Villagra A, Sotomayor EM. Histone Deacetylase 11 (HDAC11) Interaction with Ikaros Represent a Novel Mechanism of Regulation of Essential Transcriptional Factors in CD4+ T Cells Blood. 128: 864-864. DOI: 10.1182/Blood.V128.22.864.864  0.558
2016 Monteiro JB, López AMM, Peng L, Flores I, Seto E. Abstract B06: Understanding of the ovarian endometriosis and gene expression functions in neoplastic transformation Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B06  0.479
2016 Knox T, Lienlaf M, Perez P, Pabon M, Lee C, Cheng F, Sahakian E, Powers J, Deng S, Keiran S, Kozikowski A, Pinilla J, Sarnaik A, Seto E, Weber J, et al. Abstract 2331: HDAC6, new role as master regulator of PD-L1 and immune-related pathways Cancer Research. 76: 2331-2331. DOI: 10.1158/1538-7445.Am2016-2331  0.39
2016 Villagra A, Sahakian E, Seto E. Preparation and Biochemical Analysis of Classical Histone Deacetylases Methods in Enzymology. DOI: 10.1016/bs.mie.2016.04.005  0.387
2015 Contreras PS, Gonzalez-Zuñiga M, González-Hódar L, Yáñez MJ, Dulcey A, Marugan J, Seto E, Alvarez AR, Zanlungo S. Neuronal gene repression in niemann-pick type C models is mediated by the c-Abl/HDAC2 signaling pathway. Biochimica Et Biophysica Acta. PMID 26603102 DOI: 10.1016/J.Bbagrm.2015.11.006  0.375
2015 Li Y, Peng L, Seto E. Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway. Molecular and Cellular Biology. 35: 3547-65. PMID 26240284 DOI: 10.1128/Mcb.00400-15  0.498
2015 Radhakrishnan R, Li Y, Xiang S, Yuan F, Yuan Z, Telles E, Fang J, Coppola D, Shibata D, Lane WS, Zhang Y, Zhang X, Seto E. Histone Deacetylase 10 Regulates DNA Mismatch Repair and May Involve the Deacetylation of MutS Homolog 2. The Journal of Biological Chemistry. PMID 26221039 DOI: 10.1074/Jbc.M114.612945  0.699
2015 Hernandez JM, Elahi A, Clark W, Humphries LA, Wang J, Achille A, Seto E, Shibata D. The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways. Dna and Cell Biology. 34: 541-549. PMID 26061044 DOI: 10.1089/Dna.2014.2730  0.394
2015 Woan KV, Lienlaf M, Perez-Villaroel P, Lee C, Cheng F, Knox T, Woods DM, Barrios K, Powers J, Sahakian E, Wang HW, Canales J, Marante D, Smalley KS, Bergman J, ... Seto E, et al. Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation. Molecular Oncology. PMID 25957812 DOI: 10.1016/J.Molonc.2015.04.002  0.391
2015 Sun L, Kokura K, Izumi V, Koomen JM, Seto E, Chen J, Fang J. MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition. Embo Reports. 16: 689-99. PMID 25870236 DOI: 10.15252/Embr.201439792  0.466
2015 Peng L, Yuan Z, Seto E. Histone deacetylase activity assay. Methods in Molecular Biology (Clifton, N.J.). 1288: 95-108. PMID 25827877 DOI: 10.1007/978-1-4939-2474-5_7  0.731
2015 Wu M, Seto E, Zhang J. E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells. Oncotarget. 6: 11252-63. PMID 25816777 DOI: 10.18632/Oncotarget.3594  0.493
2015 Peng L, Yuan Z, Li Y, Ling H, Izumi V, Fang B, Fukasawa K, Koomen J, Chen J, Seto E. Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival. The Journal of Biological Chemistry. 290: 8904-12. PMID 25670865 DOI: 10.1074/Jbc.M114.612796  0.611
2015 Zhang L, Liu S, Liu N, Zhang Y, Liu M, Li D, Seto E, Yao TP, Shui W, Zhou J. Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity. Protein & Cell. 6: 42-54. PMID 25311840 DOI: 10.1007/S13238-014-0102-8  0.538
2014 Gonzalez-Zuñiga M, Contreras PS, Estrada LD, Chamorro D, Villagra A, Zanlungo S, Seto E, Alvarez AR. c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease. Molecular Cell. 56: 163-73. PMID 25219501 DOI: 10.1016/J.Molcel.2014.08.013  0.409
2014 Cheng F, Lienlaf M, Wang HW, Perez-Villarroel P, Lee C, Woan K, Rock-Klotz J, Sahakian E, Woods D, Pinilla-Ibarz J, Kalin J, Tao J, Hancock W, Kozikowski A, Seto E, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 193: 2850-62. PMID 25108026 DOI: 10.4049/Jimmunol.1302778  0.492
2014 Guan D, Lim JH, Peng L, Liu Y, Lam M, Seto E, Kao HY. Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death. Cell Death & Disease. 5: e1340. PMID 25032863 DOI: 10.1038/Cddis.2014.185  0.403
2014 Li J, Chen S, Cleary RA, Wang R, Gannon OJ, Seto E, Tang DD. Histone deacetylase 8 regulates cortactin deacetylation and contraction in smooth muscle tissues. American Journal of Physiology. Cell Physiology. 307: C288-95. PMID 24920679 DOI: 10.1152/Ajpcell.00102.2014  0.423
2014 Wang J, Elahi A, Ajidahun A, Clark W, Hernandez J, Achille A, Hao JH, Seto E, Shibata D. The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer. Cancer Biology & Therapy. 15: 1198-207. PMID 24919179 DOI: 10.4161/Cbt.29500  0.53
2014 Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, ... ... Seto E, et al. HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. Molecular Cell. 55: 31-46. PMID 24882211 DOI: 10.1016/J.Molcel.2014.04.028  0.389
2014 Cheng F, Lienlaf M, Perez-Villarroel P, Wang HW, Lee C, Woan K, Woods D, Knox T, Bergman J, Pinilla-Ibarz J, Kozikowski A, Seto E, Sotomayor EM, Villagra A. Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells. Molecular Immunology. 60: 44-53. PMID 24747960 DOI: 10.1016/J.Molimm.2014.02.019  0.508
2014 Seto E, Yoshida M. Erasers of histone acetylation: the histone deacetylase enzymes. Cold Spring Harbor Perspectives in Biology. 6: a018713. PMID 24691964 DOI: 10.1101/Cshperspect.A018713  0.561
2014 Monteiro JB, Colón-Díaz M, García M, Gutierrez S, Colón M, Seto E, Laboy J, Flores I. Endometriosis is characterized by a distinct pattern of histone 3 and histone 4 lysine modifications. Reproductive Sciences (Thousand Oaks, Calif.). 21: 305-18. PMID 23899551 DOI: 10.1177/1933719113497267  0.458
2014 Knox T, Lienlaf M, Perez-Villarroel P, Lee C, Sahakian E, Powers JJ, Cheng F, Canales J, Marante D, Seto E, Sotomayor EM, Villagra A, Horna P. Selective Inhibition of HDAC6 Decreases Viability of Cutaneous T-Cell Lymphoma and Improves Immune Recognition Blood. 124: 5423-5423. DOI: 10.1182/Blood.V124.21.5423.5423  0.452
2014 Perez-Villarroel P, Lienlaf M, Lee C, Cheng F, Woods D, Barrios K, Woan K, Canales J, Knox T, Marante D, Wang H, Horna P, Smalley K, Celis E, Seto E, et al. Abstract 4086: Histone deacetylase 6 (HDAC6) as a new target modulating the proliferation and immune-related pathways in melanoma Cancer Research. 74: 4086-4086. DOI: 10.1158/1538-7445.Am2014-4086  0.484
2013 Zheng H, Yang L, Peng L, Izumi V, Koomen J, Seto E, Chen J. hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1. Molecular and Cellular Biology. 33: 4960-70. PMID 24126058 DOI: 10.1128/Mcb.00874-13  0.458
2013 Woods DM, Woan K, Cheng F, Wang H, Perez-Villarroel P, Lee C, Lienlaf M, Atadja P, Seto E, Weber J, Sotomayor EM, Villagra A. The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity. Melanoma Research. 23: 341-8. PMID 23963286 DOI: 10.1097/Cmr.0B013E328364C0Ed  0.37
2013 Yang L, Song T, Chen L, Kabra N, Zheng H, Koomen J, Seto E, Chen J. Regulation of SirT1-nucleomethylin binding by rRNA coordinates ribosome biogenesis with nutrient availability. Molecular and Cellular Biology. 33: 3835-48. PMID 23897426 DOI: 10.1128/Mcb.00476-13  0.417
2013 Lienlaf M, Perez-Villarroel P, Cheng F, Lee CK, Canales J, Knox T, Marante D, Yoder SJ, Woan KV, Pinilla-Ibarz J, Seto E, Sotomayor EM, Villagra A. Role Of Histone Deacetylase 6 (HDAC6) In The Modulation Of STAT Pathways and Immune Function Of APCs Blood. 122: 1032-1032. DOI: 10.1182/Blood.V122.21.1032.1032  0.504
2013 Lienlaf M, Perez-Villarroel P, Canales J, Knox T, Cheng F, Marante D, Woods D, Woan K, Wang H, Seto E, Weber JS, Sotomayor EM, Villagra A. Abstract 5246: Histone deacetylase 6 (HDAC6) as a new modulator of the JAK/STAT pathway in melanoma. Cancer Research. 73: 5246-5246. DOI: 10.1158/1538-7445.Am2013-5246  0.482
2013 Srikumar T, Telles E, Seto E. Abstract 1742: Potential roles of histone deacetylase 11 in cell cycle regulation and cancer. Cancer Research. 73: 1742-1742. DOI: 10.1158/1538-7445.Am2013-1742  0.479
2012 Zhang X, Zhao X, Fiskus W, Lin J, Lwin T, Rao R, Zhang Y, Chan JC, Fu K, Marquez VE, Chen-Kiang S, Moscinski LC, Seto E, Dalton WS, Wright KL, et al. Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas. Cancer Cell. 22: 506-23. PMID 23079660 DOI: 10.1016/J.Ccr.2012.09.003  0.306
2012 Ling H, Peng L, Seto E, Fukasawa K. Suppression of centrosome duplication and amplification by deacetylases. Cell Cycle (Georgetown, Tex.). 11: 3779-91. PMID 23022877 DOI: 10.4161/Cc.21985  0.492
2012 Liu Y, Peng L, Seto E, Huang S, Qiu Y. Modulation of histone deacetylase 6 (HDAC6) nuclear import and tubulin deacetylase activity through acetylation. The Journal of Biological Chemistry. 287: 29168-74. PMID 22778253 DOI: 10.1074/Jbc.M112.371120  0.588
2012 Peng L, Ling H, Yuan Z, Fang B, Bloom G, Fukasawa K, Koomen J, Chen J, Lane WS, Seto E. SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. Molecular and Cellular Biology. 32: 2823-36. PMID 22586264 DOI: 10.1128/Mcb.00496-12  0.661
2012 Srisuttee R, Koh SS, Kim SJ, Malilas W, Boonying W, Cho IR, Jhun BH, Ito M, Horio Y, Seto E, Oh S, Chung YH. Hepatitis B virus X (HBX) protein upregulates β-catenin in a human hepatic cell line by sequestering SIRT1 deacetylase. Oncology Reports. 28: 276-82. PMID 22562294 DOI: 10.3892/Or.2012.1798  0.388
2012 Kahali S, Sarcar B, Prabhu A, Seto E, Chinnaiyan P. Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2437-45. PMID 22389438 DOI: 10.1096/Fj.11-193706  0.554
2012 Colón-Díaz M, Báez-Vega P, García M, Ruiz A, Monteiro JB, Fourquet J, Bayona M, Alvarez-Garriga C, Achille A, Seto E, Flores I. HDAC1 and HDAC2 are differentially expressed in endometriosis. Reproductive Sciences (Thousand Oaks, Calif.). 19: 483-92. PMID 22344732 DOI: 10.1177/1933719111432870  0.455
2012 Telles E, Seto E. Modulation of cell cycle regulators by HDACs. Frontiers in Bioscience (Scholar Edition). 4: 831-9. PMID 22202094 DOI: 10.2741/S303  0.545
2012 Woan KV, Sahakian E, Sotomayor EM, Seto E, Villagra A. Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer. Immunology and Cell Biology. 90: 55-65. PMID 22105512 DOI: 10.1038/Icb.2011.96  0.356
2012 Zhang X, Chen X, Lin J, Lwin T, Wright G, Moscinski LC, Dalton WS, Seto E, Wright K, Sotomayor E, Tao J. Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas. Oncogene. 31: 3002-8. PMID 22002311 DOI: 10.1038/Onc.2011.470  0.35
2012 Cheng F, Wang Z, Wang H, Lienlaf M, Woan KV, Perez-Villarroel P, Rock-Klotz J, Sahakian E, Knox T, Woods DM, Powers J, Han R, Merino O, Deng S, Marante D, ... ... Seto E, et al. Physical Interaction of Histone Deacetylase 6 (HDAC6) with STAT3 Regulates IL-10 Gene Expression and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs) Blood. 120: 829-829. DOI: 10.1182/Blood.V120.21.829.829  0.48
2012 Lienlaf M, Perez-Villarroel P, Cheng F, Wang H, Marante D, Yoder S, V. WK, Knox T, Lagor S, Pinilla-Ibarz J, Seto E, Sotomayor EM, Villagra A. Critical Role for Histone Deacetylase 6 (HDAC6) in the Regulation of IL-6, and the JAK/STA3 Signaling Cascade in Macrophages Blood. 120: 1039-1039. DOI: 10.1182/Blood.V120.21.1039.1039  0.457
2012 Sahakian E, Powers J, Rock-Klotz J, Marsilio A, Woan K, Merino O, Gill A, Deng S, Cheng F, Villagra A, Luekette N, Seto E, Borrello I, Sotomayor E, Pinilla JI. Abstract 4260: Histone deacetylase 11 (HDAC11) as a novel therapeutic target in the regulation of myeloid-derived suppressor cell (MDSC) Cancer Research. 72: 4260-4260. DOI: 10.1158/1538-7445.Am2012-4260  0.445
2012 Woan KV, Vazquez L, Rock-Klotz J, Wang Z, Cheng F, Wang H, Woods D, Sahakian E, Perez P, Lienlaf M, Achille A, Bergman J, Kalin J, Gill A, Powers J, ... ... Seto E, et al. Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma Cancer Research. 72: 3555-3555. DOI: 10.1158/1538-7445.Am2012-3555  0.435
2012 Woods DM, Woan KV, Wang H, Cheng F, Wang Z, Vazquez L, Perez P, Lienlaf M, Rock-Klotz J, Sahakian E, Powers J, Deng S, Oscar M, Atadja P, Seto E, et al. Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progressionin vivo Cancer Research. 72: 3554-3554. DOI: 10.1158/1538-7445.Am2012-3554  0.339
2012 Wang J, Abul E, Hernandez J, Clark W, Achille A, Hao J, Seto E, Shibata D. Abstract 3136: C-Myc-mediated transcriptional repression of HPP1 in colon cancer by recruitment of HDACs Cancer Research. 72: 3136-3136. DOI: 10.1158/1538-7445.Am2012-3136  0.571
2011 Yao TP, Seto E. The discovery of histone deacetylase. Handbook of Experimental Pharmacology. 206: v. PMID 22046630  0.429
2011 Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Molecular and Cellular Biology. 31: 4720-34. PMID 21947282 DOI: 10.1128/Mcb.06147-11  0.715
2011 Tang M, Chen B, Lin T, Li Z, Pardo C, Pampo C, Chen J, Lien CL, Wu L, Ai L, Wang H, Yao K, Oh SP, Seto E, Smith LE, et al. Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation. Proceedings of the National Academy of Sciences of the United States of America. 108: 15231-6. PMID 21896759 DOI: 10.1073/Pnas.1104662108  0.381
2011 Peng L, Seto E. Deacetylation of nonhistone proteins by HDACs and the implications in cancer. Handbook of Experimental Pharmacology. 206: 39-56. PMID 21879445 DOI: 10.1007/978-3-642-21631-2_3  0.524
2011 Kaluza D, Kroll J, Gesierich S, Yao TP, Boon RA, Hergenreider E, Tjwa M, Rössig L, Seto E, Augustin HG, Zeiher AM, Dimmeler S, Urbich C. Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin. The Embo Journal. 30: 4142-56. PMID 21847094 DOI: 10.1038/Emboj.2011.298  0.545
2011 Radiloff DR, Wakeman TP, Feng J, Schilling S, Seto E, Wang XF. Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process. Proceedings of the National Academy of Sciences of the United States of America. 108: 6591-6. PMID 21451135 DOI: 10.1073/Pnas.1017269108  0.353
2011 Wang H, Cheng F, Woan K, Sahakian E, Merino O, Rock-Klotz J, Vicente-Suarez I, Pinilla-Ibarz J, Wright KL, Seto E, Bhalla K, Villagra A, Sotomayor EM. Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10. Journal of Immunology (Baltimore, Md. : 1950). 186: 3986-96. PMID 21368229 DOI: 10.4049/Jimmunol.1001101  0.426
2011 Yang Y, Tse AK, Li P, Ma Q, Xiang S, Nicosia SV, Seto E, Zhang X, Bai W. Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation. Oncogene. 30: 2207-18. PMID 21242980 DOI: 10.1038/Onc.2010.600  0.484
2011 Cheng F, Wang Z, Wang H, Woan KV, Sahakian E, Klotz JR, Wang L, Han R, Merino O, Deng S, Vazquez L, Gill AS, Marante D, Powers J, Hancock WW, ... ... Seto E, et al. Epigenetic Modulation of STAT3 by Histone Deacetylase 6 (HDAC6) Regulates IL-10 Gene Expression and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs) Blood. 118: 519-519. DOI: 10.1182/Blood.V118.21.519.519  0.439
2011 Woan KV, Wang D, Wang Z, Cheng F, Vazquez L, Woods D, Yu Y, Sahakian E, Wang H, Telles E, Peng L, Wang L, Hancock WW, Blazar BR, Luetteke N, ... Seto E, et al. Histone Deacetylase 11 (HDAC11) Is a Regulatory Checkpoint of T-Cell Function: Implications for T-Cell Adoptive Immunotherapy Blood. 118: 359-359. DOI: 10.1182/Blood.V118.21.359.359  0.375
2011 Sahakian E, Powers J, Rock-Klotz J, Adriani M, Woan KV, Merino O, Gill AS, Deng S, Cheng F, Villagra A, Luetteke N, Seto E, Sotomayor EM, Borrello IM, Pinilla-Ibarz J. A Novel Role of Histone Deacetylase 11 (HDAC11) in Regulation of Myeloid-Derived Suppressor Cell (MDSC) Expansion Blood. 118: 2439-2439. DOI: 10.1182/Blood.V118.21.2439.2439  0.447
2010 Wong PG, Glozak MA, Cao TV, Vaziri C, Seto E, Alexandrow M. Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin. Cell Cycle (Georgetown, Tex.). 9: 4351-63. PMID 20980834 DOI: 10.4161/Cc.9.21.13596  0.512
2010 Yuan Z, Peng L, Radhakrishnan R, Seto E. Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein. The Journal of Biological Chemistry. 285: 39329-38. PMID 20947501 DOI: 10.1074/Jbc.M110.179333  0.72
2010 Yuan Z, Villagra A, Peng L, Coppola D, Glozak M, Sotomayor EM, Chen J, Lane WS, Seto E. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Molecular and Cellular Biology. 30: 3004-15. PMID 20368352 DOI: 10.1128/Mcb.01023-09  0.595
2010 Villagra A, Sotomayor EM, Seto E. Histone deacetylases and the immunological network: Implications in cancer and inflammation Oncogene. 29: 157-173. PMID 19855430 DOI: 10.1038/Onc.2009.334  0.419
2010 Woan K, Cheng F, Wang H, Rock-Klotz J, Wang Z, Yu Y, Seto E, Luetteke N, Yu X, Villagra A, Sotomayor EM. Identification of a Discrete Subpopulation of T-Cells Over-Expressing HDAC11 with a TH17 Phenotype Blood. 116: 588-588. DOI: 10.1182/Blood.V116.21.588.588  0.422
2010 Zhang X, Chen X, Lin J, Lwin T, Ely SA, Chen-Kiang S, Dalton WS, Seto E, Wright K, Sotomayor EM, Tao J. Myc Represses miR15a/Mir-16-1 Expression through Recruitment of HDAC3 In Mantle Cell Lymphoma Blood. 116: 3121-3121. DOI: 10.1182/Blood.V116.21.3121.3121  0.385
2010 Shah BD, Villagra A, Merino O, Rock-Klotz J, Woan K, Seto E, Martin P, Leonard JP, Chen-Kiang S, Tao J, Sotomayor EM. HDAC Profiling In Mantle Cell Lymphoma Unveils HDAC11 and HDAC10 as Potential Molecular Targets Blood. 116: 2506-2506. DOI: 10.1182/Blood.V116.21.2506.2506  0.479
2010 Cheng F, Wang H, Woan K, Rock-Klotz J, Wang Z, Merino O, Gill A, Marante D, Vazquez L, Seto E, Pinilla-Ibarz J, Sotomayor EM, Villagra A. Targeting Histone Deacetylase 6 (HDAC6) as a Novel Approach to Overcome T-Cell Anergy. Blood. 116: 1483-1483. DOI: 10.1182/Blood.V116.21.1483.1483  0.417
2010 Wang D, Cheng F, Yu Y, Semple K, Peng L, Telles E, Luetteke N, Seto E, Anasetti C, Sotomayor EM, Yu X. HDAC11 Inhibits T-Cell Response to Alloantigens and Reduces Gvhd In Mice. Blood. 116: 1466-1466. DOI: 10.1182/Blood.V116.21.1466.1466  0.412
2010 Zhao LY, Li Q, Seto E, Liao D. Abstract 4517: HDAC inhibitors suppress p53 expression through transcriptional repression: Implication for therapy against metastatic breast cancer Cancer Research. 70: 4517-4517. DOI: 10.1158/1538-7445.Am10-4517  0.355
2010 Seto E, Yang XJ. Regulation of histone deacetylase activities and functions by phosphorylation and dephosphorylation Handbook of Cell Signaling, 2/E. 3: 2379-2388. DOI: 10.1016/B978-0-12-374145-5.00286-2  0.415
2009 López-Soto A, Folgueras AR, Seto E, Gonzalez S. HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: Potential implications for the immunosurveillance of cancer Oncogene. 28: 2370-2382. PMID 19430493 DOI: 10.1038/Onc.2009.117  0.463
2009 Yuan Z, Rezai-Zadeh N, Zhang X, Seto E. Histone deacetylase activity assay. Methods in Molecular Biology (Clifton, N.J.). 523: 279-93. PMID 19381932 DOI: 10.1007/978-1-59745-190-1_19  0.661
2009 Glozak MA, Seto E. Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1 Journal of Biological Chemistry. 284: 11446-11453. PMID 19276081 DOI: 10.1074/Jbc.M809394200  0.579
2009 Villagra A, Cheng F, Wang HW, Suarez I, Glozak M, Maurin M, Nguyen D, Wright KL, Atadja PW, Bhalla K, Pinilla-Ibarz J, Seto E, Sotomayor EM. The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nature Immunology. 10: 92-100. PMID 19011628 DOI: 10.1038/Ni.1673  0.436
2009 Cheng F, Wang H, Luetteke N, Pinilla J, Kozikowski A, Seto E, Villagra Av, Sotomayor E. A Novel Role for Histone Deacetylase 6 (HDAC6) in the Regulation of IL-10 and Immune Tolerance Mediated by Antigen-Presenting Cells (APCs). Blood. 114: 1360-1360. DOI: 10.1182/Blood.V114.22.1360.1360  0.476
2009 Villagra A, Cheng F, Wang H, Suarez I, Glozak M, Maurin M, Nguyen D, Wright KL, Atadja PW, Bhalla K, Pinilla-Ibarz J, Seto E, Sotomayor EM. Erratum: The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance Nature Immunology. 10: 665-665. DOI: 10.1038/Ni0609-665C  0.493
2008 Ellis DJ, Yuan Z, Seto E. Determination of protein lysine deacetylation. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 14.12. PMID 19016433 DOI: 10.1002/0471140864.Ps1412S54  0.713
2008 Yang XJ, Seto E. Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications Molecular Cell. 31: 449-461. PMID 18722172 DOI: 10.1016/J.Molcel.2008.07.002  0.53
2008 Roy S, Shor AC, Bagui TK, Seto E, Pledger WJ. Histone deacetylase 5 represses the transcription of cyclin D3 Journal of Cellular Biochemistry. 104: 2143-2154. PMID 18404677 DOI: 10.1002/Jcb.21771  0.531
2008 Yang XJ, Seto E. The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men Nature Reviews Molecular Cell Biology. 9: 206-218. PMID 18292778 DOI: 10.1038/Nrm2346  0.45
2008 Villagra Av, Maurin Mm, Cheng F, Wang H, Dessureault S, Seto E, Tao J, Wright K, Pinilla J, Sotomayor EM. Histone Deacetylase 11 (HDAC11) as a Novel Molecular Target in Mantle Cell Lymphoma Blood. 112: 4494-4494. DOI: 10.1182/Blood.V112.11.4494.4494  0.5
2008 Ellis DJP, Yuan Z, Seto E. Determination of protein lysine deacetylation Current Protocols in Protein Science. 14.12.1-14.12.14. DOI: 10.1002/0471140864.ps1412s54  0.529
2007 Yuan Z, Seto E. A functional link between SIRT1 deacetylase and NBS1 in DNA damage response Cell Cycle. 6: 2869-2871. PMID 18156798 DOI: 10.4161/Cc.6.23.5026  0.556
2007 Villagra A, Ulloa N, Zhang X, Yuan Z, Sotomayor E, Seto E. Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression Journal of Biological Chemistry. 282: 35457-35470. PMID 17925399 DOI: 10.1074/Jbc.M701719200  0.682
2007 Glozak MA, Seto E. Histone deacetylases and cancer Oncogene. 26: 5420-5432. PMID 17694083 DOI: 10.1038/sj.onc.1210610  0.49
2007 Yang XJ, Seto E. HATs and HDACs: From structure, function and regulation to novel strategies for therapy and prevention Oncogene. 26: 5310-5318. PMID 17694074 DOI: 10.1038/sj.onc.1210599  0.481
2007 Zhang X, Yuan Z, Zhang Y, Yong S, Salas-Burgos A, Koomen J, Olashaw N, Parsons JT, Yang XJ, Dent SR, Yao TP, Lane WS, Seto E. HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin Molecular Cell. 27: 197-213. PMID 17643370 DOI: 10.1016/J.Molcel.2007.05.033  0.612
2007 Yuan Z, Zhang X, Sengupta N, Lane WS, Seto E. SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Molecular Cell. 27: 149-62. PMID 17612497 DOI: 10.1016/J.Molcel.2007.05.029  0.594
2007 Feng W, Lu Z, Luo RZ, Zhang X, Seto E, Liao WS, Yu Y. Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. International Journal of Cancer. Journal International Du Cancer. 120: 1664-8. PMID 17230502 DOI: 10.1002/Ijc.22474  0.428
2007 Grégoire S, Xiao L, Nie J, Zhang X, Xu M, Li J, Wong J, Seto E, Yang XJ. Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2 Molecular and Cellular Biology. 27: 1280-1295. PMID 17158926 DOI: 10.1128/Mcb.00882-06  0.578
2007 Joshi B, Rastogi S, Morris M, Carastro LM, DeCook C, Seto E, Chellappan SP. Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites. The Biochemical Journal. 401: 155-66. PMID 16918502 DOI: 10.1042/Bj20060364  0.388
2007 Wang H, Cheng F, Nguyen D, Suarez I, Wright K, Atadja A, Seto E, Bhalla K, Villagra A, Sotomayor E. A Novel Role of Histone Deacetylase 11 (HDAC11) in the Regulation of IL-10 Production and Immune Tolerance Mediated by Antigen-Presenting Cells. Blood. 110: 1330-1330. DOI: 10.1182/Blood.V110.11.1330.1330  0.467
2006 Lee H, Sengupta N, Villagra A, Rezai-Zadeh N, Seto E. Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation Molecular and Cellular Biology. 26: 5259-5269. PMID 16809764 DOI: 10.1128/Mcb.01971-05  0.582
2006 Xu Y, Sengupta PK, Seto E, Smith BD. Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression. The Journal of Biological Chemistry. 281: 9260-70. PMID 16464847 DOI: 10.1074/Jbc.M511724200  0.562
2005 Glozak MA, Sengupta N, Zhang X, Seto E. Acetylation and deacetylation of non-histone proteins. Gene. 363: 15-23. PMID 16289629 DOI: 10.1016/J.Gene.2005.09.010  0.546
2005 Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ, Chen J. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. The Embo Journal. 24: 3279-90. PMID 16107876 DOI: 10.1038/Sj.Emboj.7600791  0.373
2005 Bali P, Pranpat M, Bradner J, Balasis M, Fiskus W, Guo F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, Seto E, Bhalla K. Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors. The Journal of Biological Chemistry. 280: 26729-34. PMID 15937340 DOI: 10.1074/Jbc.C500186200  0.498
2005 Baumeister P, Luo S, Skarnes WC, Sui G, Seto E, Shi Y, Lee AS. Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Molecular and Cellular Biology. 25: 4529-40. PMID 15899857 DOI: 10.1128/Mcb.25.11.4529-4540.2005  0.445
2005 Gao Z, Chiao P, Zhang X, Zhang X, Lazar MA, Seto E, Young HA, Ye J. Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. The Journal of Biological Chemistry. 280: 21091-8. PMID 15811852 DOI: 10.1074/Jbc.M500754200  0.435
2005 Zhang X, Ozawa Y, Lee H, Wen YD, Tan TH, Wadzinski BE, Seto E. Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4. Genes & Development. 19: 827-39. PMID 15805470 DOI: 10.1101/Gad.1286005  0.737
2004 Sengupta N, Seto E. Regulation of histone deacetylase activities. Journal of Cellular Biochemistry. 93: 57-67. PMID 15352162 DOI: 10.1002/Jcb.20179  0.603
2004 Zhang X, Wharton W, Yuan Z, Tsai SC, Olashaw N, Seto E. Activation of the growth-differentiation factor 11 gene by the histone deacetylase (HDAC) inhibitor trichostatin A and repression by HDAC3. Molecular and Cellular Biology. 24: 5106-18. PMID 15169878 DOI: 10.1128/Mcb.24.12.5106-5118.2004  0.774
2004 Nguyen N, Zhang X, Olashaw N, Seto E. Molecular cloning and functional characterization of the transcription factor YY2. The Journal of Biological Chemistry. 279: 25927-34. PMID 15087442 DOI: 10.1074/Jbc.M402525200  0.687
2004 Gyory I, Wu J, Fejér G, Seto E, Wright KL. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nature Immunology. 5: 299-308. PMID 14985713 DOI: 10.1038/Ni1046  0.466
2004 Rezai-Zadeh N, Tsai SC, Wen YD, Yao YL, Yang WM, Seto E. Histone deacetylases: purification of the enzymes, substrates, and assay conditions. Methods in Enzymology. 377: 167-79. PMID 14979024 DOI: 10.1016/S0076-6879(03)77009-8  0.775
2004 Lee H, Rezai-Zadeh N, Seto E. Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A. Molecular and Cellular Biology. 24: 765-73. PMID 14701748 DOI: 10.1128/Mcb.24.2.765-773.2004  0.571
2003 Kapustin GV, Fejér G, Gronlund JL, McCafferty DG, Seto E, Etzkorn FA. Phosphorus-based SAHA analogues as histone deacetylase inhibitors. Organic Letters. 5: 3053-6. PMID 12916979 DOI: 10.1021/Ol035056N  0.424
2003 Seto E. Histone modifications Methods. 31: 1-2. PMID 12893167 DOI: 10.1016/S1046-2023(03)00081-1  0.43
2003 Weiss C, Schneider S, Wagner EF, Zhang X, Seto E, Bohmann D. JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. The Embo Journal. 22: 3686-95. PMID 12853483 DOI: 10.1093/Emboj/Cdg364  0.396
2003 Rezai-Zadeh N, Zhang X, Namour F, Fejer G, Wen YD, Yao YL, Gyory I, Wright K, Seto E. Targeted recruitment of a histone H4-specific methyltransferase by the transcription factor YY1. Genes & Development. 17: 1019-29. PMID 12704081 DOI: 10.1101/Gad.1068003  0.792
2003 Yang XJ, Seto E. Collaborative spirit of histone deacetylases in regulating chromatin structure and gene expression. Current Opinion in Genetics & Development. 13: 143-53. PMID 12672491 DOI: 10.1016/S0959-437X(03)00015-7  0.581
2003 Györy I, Fejér G, Ghosh N, Seto E, Wright KL. Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines. Journal of Immunology (Baltimore, Md. : 1950). 170: 3125-33. PMID 12626569 DOI: 10.4049/Jimmunol.170.6.3125  0.454
2003 Wen YD, Cress WD, Roy AL, Seto E. Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I. The Journal of Biological Chemistry. 278: 1841-7. PMID 12393887 DOI: 10.1074/Jbc.M206528200  0.758
2002 Tussié-Luna MI, Bayarsaihan D, Seto E, Ruddle FH, Roy AL. Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta. Proceedings of the National Academy of Sciences of the United States of America. 99: 12807-12. PMID 12239342 DOI: 10.1073/Pnas.192464499  0.494
2002 Sun JM, Chen HY, Moniwa M, Litchfield DW, Seto E, Davie JR. The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2. The Journal of Biological Chemistry. 277: 35783-6. PMID 12176973 DOI: 10.1074/Jbc.C200378200  0.46
2002 Tsai SC, Seto E. Regulation of histone deacetylase 2 by protein kinase CK2. The Journal of Biological Chemistry. 277: 31826-33. PMID 12082111 DOI: 10.1074/Jbc.M204149200  0.706
2002 Gavva NR, Wen SC, Daftari P, Moniwa M, Yang WM, Yang-Feng LP, Seto E, Davie JR, Shen CK. NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor. Genomics. 79: 423-31. PMID 11863372 DOI: 10.1006/Geno.2002.6714  0.755
2002 Yang WM, Tsai SC, Wen YD, Fejer G, Seto E. Functional domains of histone deacetylase-3. The Journal of Biological Chemistry. 277: 9447-54. PMID 11779848 DOI: 10.1074/Jbc.M105993200  0.829
2001 Guo J, Casolaro V, Seto E, Yang WM, Chang C, Seminario MC, Keen J, Georas SN. Yin-Yang 1 activates interleukin-4 gene expression in T cells. The Journal of Biological Chemistry. 276: 48871-8. PMID 11687571 DOI: 10.1074/Jbc.M101592200  0.343
2001 Osborne A, Zhang H, Yang W, Seto E, Blanck G. Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase, I-hypersensitive chromatin conformation Molecular and Cellular Biology. 21: 6495-6506. PMID 11533238 DOI: 10.1128/Mcb.21.19.6495-6506.2001  0.515
2001 Yang WM, Yao YL, Seto E. The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1. The Embo Journal. 20: 4814-25. PMID 11532945 DOI: 10.1093/Emboj/20.17.4814  0.715
2001 Yao YL, Yang WM, Seto E. Regulation of transcription factor YY1 by acetylation and deacetylation. Molecular and Cellular Biology. 21: 5979-91. PMID 11486036 DOI: 10.1128/Mcb.21.17.5979-5991.2001  0.723
2001 Franco PJ, Farooqui M, Seto E, Wei LN. The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. Molecular Endocrinology (Baltimore, Md.). 15: 1318-28. PMID 11463856 DOI: 10.1210/Mend.15.8.0682  0.559
2001 Wagner M, Brosch G, Zwerschke W, Seto E, Loidl P, Jansen-Dürr P. Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2. Febs Letters. 499: 101-6. PMID 11418121 DOI: 10.1016/S0014-5793(01)02524-8  0.542
2001 Lai A, Kennedy BK, Barbie DA, Bertos NR, Yang XJ, Theberge MC, Tsai SC, Seto E, Zhang Y, Kuzmichev A, Lane WS, Reinberg D, Harlow E, Branton PE. RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest. Molecular and Cellular Biology. 21: 2918-32. PMID 11283269 DOI: 10.1128/Mcb.21.8.2918-2932.2001  0.713
2001 Wu WS, Vallian S, Seto E, Yang WM, Edmondson D, Roth S, Chang KS. The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases Molecular and Cellular Biology. 21: 2259-2268. PMID 11259576 DOI: 10.1128/Mcb.21.7.2259-2268.2001  0.59
2000 Tsai SC, Valkov N, Yang WM, Gump J, Sullivan D, Seto E. Histone deacetylase interacts directly with DNA topoisomerase II. Nature Genetics. 26: 349-53. PMID 11062478 DOI: 10.1038/81671  0.723
2000 Jepsen K, Hermanson O, Onami TM, Gleiberman AS, Lunyak V, McEvilly RJ, Kurokawa R, Kumar V, Liu F, Seto E, Hedrick SM, Mandel G, Glass CK, Rose DW, Rosenfeld MG. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell. 102: 753-63. PMID 11030619 DOI: 10.1016/S0092-8674(00)00064-7  0.473
2000 Wei LN, Hu X, Chandra D, Seto E, Farooqui M. Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. The Journal of Biological Chemistry. 275: 40782-7. PMID 11006275 DOI: 10.1074/Jbc.M004821200  0.56
2000 Wharton W, Savell J, Cress WD, Seto E, Pledger WJ. Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. The Journal of Biological Chemistry. 275: 33981-7. PMID 10945992 DOI: 10.1074/Jbc.M005600200  0.383
2000 Wen YD, Perissi V, Staszewski LM, Yang WM, Krones A, Glass CK, Rosenfeld MG, Seto E. The histone deacetylase-3 complex contains nuclear receptor corepressors. Proceedings of the National Academy of Sciences of the United States of America. 97: 7202-7. PMID 10860984 DOI: 10.1073/Pnas.97.13.7202  0.719
2000 Cress WD, Seto E. Histone deacetylases, transcriptional control, and cancer. Journal of Cellular Physiology. 184: 1-16. PMID 10825229 DOI: 10.1002/(Sici)1097-4652(200007)184:1<1::Aid-Jcp1>3.0.Co;2-7  0.577
2000 Juan LJ, Shia WJ, Chen MH, Yang WM, Seto E, Lin YS, Wu CW. Histone deacetylases specifically down-regulate p53-dependent gene activation Journal of Biological Chemistry. 275: 20436-20443. PMID 10777477 DOI: 10.1074/Jbc.M000202200  0.47
2000 Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia Journal of Biological Chemistry. 275: 651-656. PMID 10617663 DOI: 10.1074/Jbc.275.1.651  0.387
1999 Sasaki S, Lesoon-Wood LA, Dey A, Kuwata T, Weintraub BD, Humphrey G, Yang WM, Seto E, Yen PM, Howard BH, Ozato K. Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene. The Embo Journal. 18: 5389-98. PMID 10508171 DOI: 10.1093/Emboj/18.19.5389  0.503
1999 Lai A, Lee JM, Yang WM, Decaprio JA, Kaelin WG, Seto E, Branton PE. RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins Molecular and Cellular Biology. 19: 6632-6641. PMID 10490602 DOI: 10.1128/Mcb.19.10.6632  0.564
1999 Thomas MJ, Seto E. Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key? Gene. 236: 197-208. PMID 10452940 DOI: 10.1016/S0378-1119(99)00261-9  0.595
1999 Tang CM, Westling J, Seto E. trans repression of the human metallothionein IIA gene promoter by PZ120, a novel 120-kilodalton zinc finger protein Molecular and Cellular Biology. 19: 680-689. PMID 9858591 DOI: 10.1128/Mcb.19.1.680  0.468
1998 Azizan A, Cong YS, Shain K, Tsai SC, Yao YL, Olashaw N, Seto E. Transactivation by expression of the hepatitis B virus X protein with an inducible system. Molecular Biology Reports. 25: 231-6. PMID 9870613 DOI: 10.1023/A:1006933629329  0.697
1998 Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Molecular and Cellular Biology. 18: 7176-84. PMID 9819404 DOI: 10.1128/Mcb.18.12.7176  0.506
1998 Zeng Y, Tang CM, Yao YL, Yang WM, Seto E. Cloning and characterization of the mouse histone deacetylase-2 gene. The Journal of Biological Chemistry. 273: 28921-30. PMID 9786895 DOI: 10.1074/Jbc.273.44.28921  0.688
1998 Yao YL, Dupont BR, Ghosh S, Fang Y, Leach RJ, Seto E. Cloning, chromosomal localization and promoter analysis of the human transcription factor YY1. Nucleic Acids Research. 26: 3776-83. PMID 9685495 DOI: 10.1093/Nar/26.16.3776  0.613
1998 McNeil S, Guo B, Stein JL, Lian JB, Bushmeyer S, Seto E, Atchison ML, Penman S, van Wijnen AJ, Stein GS. Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. Journal of Cellular Biochemistry. 68: 500-10. PMID 9493912 DOI: 10.1002/(Sici)1097-4644(19980315)68:4<500::Aid-Jcb9>3.0.Co;2-U  0.385
1997 Yang WM, Yao YL, Sun JM, Davie JR, Seto E. Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. The Journal of Biological Chemistry. 272: 28001-7. PMID 9346952 DOI: 10.1074/Jbc.272.44.28001  0.678
1997 Cong YS, Yao YL, Yang WM, Kuzhandaivelu N, Seto E. The hepatitis B virus X-associated protein, XAP3, is a protein kinase C-binding protein. The Journal of Biological Chemistry. 272: 16482-9. PMID 9195957 DOI: 10.1074/Jbc.272.26.16482  0.584
1997 Söderström M, Vo A, Heinzel T, Lavinsky RM, Yang WM, Seto E, Peterson DA, Rosenfeld MG, Glass CK. Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Molecular Endocrinology (Baltimore, Md.). 11: 682-92. PMID 9171232 DOI: 10.1210/Mend.11.6.0018  0.381
1997 Laherty CD, Yang WM, Sun JM, Davie JR, Seto E, Eisenman RN. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell. 89: 349-56. PMID 9150134 DOI: 10.1016/S0092-8674(00)80215-9  0.598
1997 Heinzel T, Lavinsky RM, Mullen TM, Söderstrom M, Laherty CD, Torchia J, Yang WM, Brard G, Ngo SD, Davie JR, Seto E, Eisenman RN, Rose DW, Glass CK, Rosenfeld MG. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature. 387: 43-8. PMID 9139820 DOI: 10.1038/387043A0  0.51
1996 Kuzhandaivelu N, Cong YS, Inouye C, Yang WM, Seto E. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation Nucleic Acids Research. 24: 4741-4750. PMID 8972861 DOI: 10.1093/Nar/24.23.4741  0.32
1996 Yang WM, Inouye C, Zeng Y, Bearss D, Seto E. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3 Proceedings of the National Academy of Sciences of the United States of America. 93: 12845-12850. PMID 8917507 DOI: 10.1073/Pnas.93.23.12845  0.478
1996 Tang CM, Tomkinson AE, Lane WS, Wold MS, Seto E. Replication protein A is a component of a complex that binds the human metallothionein IIA gene transcription start site. The Journal of Biological Chemistry. 271: 21637-44. PMID 8702952 DOI: 10.1074/Jbc.271.35.21637  0.465
1996 Ghosh S, Toth C, Peterlin BM, Seto E. Synergistic activation of transcription by the mutant and wild-type minimal transcriptional activation domain of VP16 Journal of Biological Chemistry. 271: 9911-9918. PMID 8626627 DOI: 10.1074/Jbc.271.17.9911  0.393
1996 Adrian GS, Seto E, Fischbach KS, Rivera EV, Adrian EK, Herbert DC, Walter CA, Weaker FJ, Bowman BH. YY1 and Sp1 transcription factors bind the human transferrin gene in an age-related manner Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 51: B66-B75. PMID 8548503 DOI: 10.1093/Gerona/51A.1.B66  0.365
1995 Lewis BA, Tullis G, Seto E, Horikoshi N, Weinmann R, Shenk T. Adenovirus E1A proteins interact with the cellular YY1 transcription factor Journal of Virology. 69: 1628-1636. PMID 7853498 DOI: 10.1128/Jvi.69.3.1628-1636.1995  0.42
1995 Yang WM, Inouye CJ, Seto E. Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity Journal of Biological Chemistry. 270: 15187-15193. PMID 7541038 DOI: 10.1074/Jbc.270.25.15187  0.453
1994 Inouye CJ, Seto E. Relief of YY1-induced transcriptional repression by protein-protein interaction with the nucleolar phosphoprotein B23 Journal of Biological Chemistry. 269: 6506-6510. PMID 8120001  0.361
1993 Seto E, Lewist B, Shenk T. Interaction between transcription factors Spl and YY1 Nature. 365: 462-464. PMID 8003102 DOI: 10.1038/365462A0  0.427
1992 Seto E, Usheva A, Zambetti GP, Momand J, Horikoshi N, Weinmann R, Levine AJ, Shenk T. Wild-type p53 binds to the TATA-binding protein and represses transcription Proceedings of the National Academy of Sciences of the United States of America. 89: 12028-12032. PMID 1465435 DOI: 10.1073/Pnas.89.24.12028  0.383
1991 Seto E, Yen TSB. Mutual Functional Antagonism of the Simian Virus 40 T Antigen and the Hepatitis B Virus trans Activator Journal of Virology. 65: 2351-2356. PMID 1850016 DOI: 10.1128/Jvi.65.5.2351-2356.1991  0.319
1991 Seto E, Shi Y, Shenk T. YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro Nature. 354: 241-245. PMID 1720509 DOI: 10.1038/354241A0  0.421
1991 Shi Y, Seto E, Chang LS, Shenk T. Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein Cell. 67: 377-388. PMID 1655281 DOI: 10.1016/0092-8674(91)90189-6  0.459
1990 Seto E, Mitchell PJ, Yen TSB. Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors Nature. 344: 72-74. PMID 2154703 DOI: 10.1038/344072A0  0.423
1989 Seto E, Zhou DX, Matija Peterlin B, Benedict Yen TS. trans-Activation by the hepatitis B virus X protein shows cell-type specificity Virology. 173: 764-766. PMID 2596037 DOI: 10.1016/0042-6822(89)90594-1  0.346
1988 Seto E, Yen TSB, Peterlin BM, Ou JH. Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein Proceedings of the National Academy of Sciences of the United States of America. 85: 8286-8290. PMID 3186723 DOI: 10.1073/Pnas.85.21.8286  0.306
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