| Year |
Citation |
Score |
| 2023 |
Miguez A, Gomis C, Vila C, Monguió-Tortajada M, Fernández-García S, Bombau G, Galofré M, García-Bravo M, Sanders P, Fernández-Medina H, Poquet B, Salado-Manzano C, Roura S, Alberch J, Segovia JC, et al. Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease. Cellular and Molecular Life Sciences : Cmls. 80: 238. PMID 37535170 DOI: 10.1007/s00018-023-04882-w |
0.374 |
|
| 2023 |
Ballasch I, García-García E, Vila C, Pérez-González A, Sancho-Balsells A, Fernández J, Soto D, Puigdellívol M, Gasull X, Alberch J, Rodríguez MJ, Canals JM, Giralt A. Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration. Brain, Behavior, and Immunity. 109: 144-161. PMID 36702234 DOI: 10.1016/j.bbi.2023.01.016 |
0.636 |
|
| 2022 |
Solés-Tarrés I, Cabezas-Llobet N, Lefranc B, Leprince J, Alberch J, Vaudry D, Xifró X. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington's Disease Models: Role of PAC1 Receptor. Frontiers in Pharmacology. 12: 797541. PMID 35153755 DOI: 10.3389/fphar.2021.797541 |
0.359 |
|
| 2021 |
Pérez-Sisqués L, Solana-Balaguer J, Campoy-Campos G, Martín-Flores N, Sancho-Balsells A, Vives-Isern M, Soler-Palazón F, Garcia-Forn M, Masana M, Alberch J, Pérez-Navarro E, Giralt A, Malagelada C. RTP801/REDD1 Is Involved in Neuroinflammation and Modulates Cognitive Dysfunction in Huntington's Disease. Biomolecules. 12. PMID 35053183 DOI: 10.3390/biom12010034 |
0.322 |
|
| 2021 |
García-García E, Chaparro-Cabanillas N, Coll-Manzano A, Carreras-Caballé M, Giralt A, Del Toro D, Alberch J, Masana M, Rodríguez MJ. Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain. International Journal of Molecular Sciences. 22. PMID 34884823 DOI: 10.3390/ijms222313018 |
0.364 |
|
| 2021 |
Pérez-Sisqués L, Sancho-Balsells A, Solana-Balaguer J, Campoy-Campos G, Vives-Isern M, Soler-Palazón F, Anglada-Huguet M, López-Toledano MÁ, Mandelkow EM, Alberch J, Giralt A, Malagelada C. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death & Disease. 12: 616. PMID 34131105 DOI: 10.1038/s41419-021-03899-y |
0.322 |
|
| 2021 |
Pérez-Sisqués L, Sancho-Balsells A, Solana-Balaguer J, Campoy-Campos G, Vives-Isern M, Soler-Palazón F, Anglada-Huguet M, López-Toledano MÁ, Mandelkow EM, Alberch J, Giralt A, Malagelada C. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death & Disease. 12: 616. PMID 34131105 DOI: 10.1038/s41419-021-03899-y |
0.322 |
|
| 2021 |
Pérez-Sisqués L, Martín-Flores N, Masana M, Solana J, Llobet A, Romaní-Aumedes J, Canal M, Campoy G, García-García E, Sánchez-Fernández N, Fernández-García S, Gilbert JP, Rodríguez MJ, Man HY, Feinstein E, ... ... Alberch J, et al. RTP801 regulates motor cortex synaptic transmission and learning. Experimental Neurology. 113755. PMID 33984337 DOI: 10.1016/j.expneurol.2021.113755 |
0.313 |
|
| 2020 |
Vidal-Sancho L, Fernández-García S, Solés-Tarrés I, Alberch J, Xifró X. Decreased Myocyte Enhancer Factor 2 Levels in the Hippocampus of Huntington's Disease Mice Are Related to Cognitive Dysfunction. Molecular Neurobiology. PMID 32757160 DOI: 10.1007/S12035-020-02041-X |
0.387 |
|
| 2020 |
Martín-Flores N, Pérez-Sisqués L, Creus-Muncunill J, Masana M, Ginés S, Alberch J, Pérez-Navarro E, Malagelada C. Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease. Cell Death & Disease. 11: 569. PMID 32732871 DOI: 10.1038/S41419-020-02775-5 |
0.423 |
|
| 2020 |
Kim A, García-García E, Straccia M, Comella-Bolla A, Miguez A, Masana M, Alberch J, Canals JM, Rodríguez MJ. Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease. Frontiers in Cellular Neuroscience. 14: 163. PMID 32625064 DOI: 10.3389/Fncel.2020.00163 |
0.671 |
|
| 2020 |
Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, et al. Modulation of dopamine D receptors via histamine H receptors is a novel therapeutic target for Huntington's disease. Elife. 9. PMID 32513388 DOI: 10.7554/Elife.51093 |
0.435 |
|
| 2020 |
Fernández-García S, Sancho-Balsells A, Longueville S, Hervé D, Gruart A, Delgado-García JM, Alberch J, Giralt A. Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy. Cell Death & Disease. 11: 411. PMID 32483154 DOI: 10.1038/S41419-020-2615-9 |
0.46 |
|
| 2020 |
Sancho-Balsells A, Brito V, Fernández B, Pardo M, Straccia M, Ginés S, Alberch J, Hernández I, Arranz B, Canals JM, Giralt A. Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1. Frontiers in Cellular Neuroscience. 14: 93. PMID 32477064 DOI: 10.3389/Fncel.2020.00093 |
0.678 |
|
| 2020 |
Fernández-García S, Orlandi JG, García-Díaz Barriga GA, Rodríguez MJ, Masana M, Soriano J, Alberch J. Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington's disease. Bmc Biology. 18: 58. PMID 32466798 DOI: 10.1186/S12915-020-00794-4 |
0.337 |
|
| 2020 |
Comella-Bolla A, Orlandi JG, Miguez A, Straccia M, García-Bravo M, Bombau G, Galofré M, Sanders P, Carrere J, Segovia JC, Blasi J, Allen ND, Alberch J, Soriano J, Canals JM. Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation. Molecular Neurobiology. PMID 32356172 DOI: 10.1007/S12035-020-01907-4 |
0.675 |
|
| 2020 |
Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, et al. Author response: Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease Elife. DOI: 10.7554/Elife.51093.Sa2 |
0.302 |
|
| 2019 |
Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martín-Ibáñez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, García-Torralba A, Pascual M, Pumarola M, Alberch J, Ginés S, et al. Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Experimental Neurology. 113095. PMID 31712124 DOI: 10.1016/J.Expneurol.2019.113095 |
0.622 |
|
| 2019 |
Creus-Muncunill J, Badillos-Rodríguez R, Garcia-Forn M, Masana M, Garcia-Díaz Barriga G, Guisado-Corcoll A, Alberch J, Malagelada C, Delgado-García JM, Gruart A, Pérez-Navarro E. Increased translation as a novel pathogenic mechanism in Huntington's disease. Brain : a Journal of Neurology. PMID 31365052 DOI: 10.1093/Brain/Awz230 |
0.426 |
|
| 2019 |
de Pins B, Cifuentes-Díaz C, Thamila Farah A, López-Molina L, Montalban E, Sancho-Balsells A, López A, Ginés S, Delgado-García JM, Alberch J, Gruart A, Girault JA, Giralt A. Conditional BDNF delivery from astrocytes rescues memory deficits, spine density and synaptic properties in the 5xFAD mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30700530 DOI: 10.1523/Jneurosci.2121-18.2019 |
0.439 |
|
| 2019 |
Montalban E, Al-Massadi O, Sancho-Balsells A, Brito V, de Pins B, Alberch J, Ginés S, Girault JA, Giralt A. Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes. Translational Psychiatry. 9: 3. PMID 30664624 DOI: 10.1038/S41398-018-0352-Y |
0.337 |
|
| 2019 |
Rodríguez-Urgellés E, Fernández-García S, Orlandi J, Barriga GG, Rodríguez M, Soriano J, Alberch J, Masana M. Brain-derived neurotrophic factor modulates neuronal network structure and dynamics in striatal cultures: Implications for Huntington's disease European Neuropsychopharmacology. 29: S160-S161. DOI: 10.1016/J.Euroneuro.2018.11.280 |
0.403 |
|
| 2018 |
Blázquez G, Castañé A, Saavedra A, Masana M, Alberch J, Pérez-Navarro E. Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase. Frontiers in Behavioral Neuroscience. 12: 317. PMID 30760987 DOI: 10.3389/Fnbeh.2018.00317 |
0.303 |
|
| 2018 |
García-Forn M, Martínez-Torres S, García-Díaz Barriga G, Alberch J, Milà M, Azkona G, Pérez-Navarro E. Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease. Neurobiology of Disease. 120: 88-97. PMID 30176350 DOI: 10.1016/J.Nbd.2018.08.024 |
0.376 |
|
| 2018 |
Saavedra A, Ballesteros JJ, Tyebji S, Martínez-Torres S, Blázquez G, López-Hidalgo R, Azkona G, Alberch J, Martín ED, Pérez-Navarro E. Proteolytic Degradation of Hippocampal STEP in LTP and Learning. Molecular Neurobiology. PMID 29948948 DOI: 10.1007/S12035-018-1170-1 |
0.368 |
|
| 2018 |
Cabezas-Llobet N, Camprubí S, García B, Alberch J, Xifró X. Human alpha 1-antitrypsin protects neurons and glial cells against oxygen and glucose deprivation through inhibition of interleukins expression. Biochimica Et Biophysica Acta. PMID 29857082 DOI: 10.1016/J.Bbagen.2018.05.017 |
0.365 |
|
| 2018 |
Suelves N, Miguez A, López-Benito S, Barriga GG, Giralt A, Alvarez-Periel E, Arévalo JC, Alberch J, Ginés S, Brito V. Early Downregulation of p75 by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice. Molecular Neurobiology. PMID 29804232 DOI: 10.1007/S12035-018-1126-5 |
0.465 |
|
| 2018 |
Saavedra A, García-Díaz Barriga G, Pérez-Navarro E, Alberch J. Huntington's disease: novel therapeutic perspectives hanging in the balance. Expert Opinion On Therapeutic Targets. 1-15. PMID 29671352 DOI: 10.1080/14728222.2018.1465930 |
0.423 |
|
| 2018 |
Cabezas-Llobet N, Vidal-Sancho L, Masana M, Fournier A, Alberch J, Vaudry D, Xifró X. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Enhances Hippocampal Synaptic Plasticity and Improves Memory Performance in Huntington's Disease. Molecular Neurobiology. 55: 8263-8277. PMID 29526016 DOI: 10.1007/S12035-018-0972-5 |
0.395 |
|
| 2018 |
Creus-Muncunill J, Rué L, Alcalá-Vida R, Badillos-Rodríguez R, Romaní-Aumedes J, Marco S, Alberch J, Perez-Otaño I, Malagelada C, Pérez-Navarro E. Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration. Molecular Neurobiology. PMID 29460266 DOI: 10.1007/S12035-018-0956-5 |
0.505 |
|
| 2017 |
Alvarez-Periel E, Puigdellívol M, Brito V, Plattner F, Bibb JA, Alberch J, Ginés S. Cdk5 Contributes to Huntington's Disease Learning and Memory Deficits via Modulation of Brain Region-Specific Substrates. Molecular Neurobiology. PMID 29288339 DOI: 10.1007/S12035-017-0828-4 |
0.317 |
|
| 2017 |
Cases S, Saavedra A, Tyebji S, Giralt A, Alberch J, Pérez-Navarro E. Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF. Molecular and Cellular Neurosciences. PMID 29122705 DOI: 10.1016/J.Mcn.2017.11.003 |
0.405 |
|
| 2017 |
Giralt A, Gómez-Climent MÁ, Alcalá R, Bretin S, Bertrand D, María Delgado-García J, Pérez-Navarro E, Alberch J, Gruart A. The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice. Neuropharmacology. PMID 28603025 DOI: 10.1016/J.Neuropharm.2017.06.009 |
0.352 |
|
| 2017 |
Giralt A, Brito V, Chevy Q, Simonnet C, Otsu Y, Cifuentes-Díaz C, de Pins B, Coura R, Alberch J, Ginés S, Poncer JC, Girault JA. Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model. Nature Communications. 8: 15592. PMID 28555636 DOI: 10.1038/Ncomms15592 |
0.422 |
|
| 2017 |
García-Díaz Barriga G, Giralt A, Anglada-Huguet M, Gaja-Capdevila N, Orlandi JG, Soriano J, Canals JM, Alberch J. 7,8 Dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway. Human Molecular Genetics. PMID 28541476 DOI: 10.1093/Hmg/Ddx198 |
0.471 |
|
| 2017 |
Martín-Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Barriga GG, Edel MJ, Vicario-Abejón C, Alberch J, Girault JA, Chan S, Kastner P, et al. Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development (Cambridge, England). PMID 28289129 DOI: 10.1242/Dev.138248 |
0.686 |
|
| 2017 |
Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E. Chelerythrine promotes Ca(2+)-dependent calpain activation in neuronal cells in a PKC-independent manner. Biochimica Et Biophysica Acta. PMID 28130160 DOI: 10.1016/J.Bbagen.2017.01.021 |
0.386 |
|
| 2017 |
Moreno B, Vila G, Fernandez-Diez B, Vázquez R, Penta Ad, Errea O, Escala N, Miguez A, Alberch J, Villoslada P. Methylthioadenosine promotes remyelination by inducing oligodendrocyte differentiation Multiple Sclerosis and Demyelinating Disorders. 2: 1-13. DOI: 10.1186/S40893-017-0020-8 |
0.326 |
|
| 2016 |
Canal M, Martín-Flores N, Pérez-Sisqués L, Romaní-Aumedes J, Altas B, Man HY, Kawabe H, Alberch J, Malagelada C. Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease. Oncotarget. PMID 27494837 DOI: 10.18632/Oncotarget.11020 |
0.426 |
|
| 2016 |
Anglada-Huguet M, Giralt A, Rué L, Alberch J, Xifró X. Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease. Biochimica Et Biophysica Acta. PMID 27063456 DOI: 10.1016/J.Bbadis.2016.04.002 |
0.453 |
|
| 2015 |
Pont L, Benavente F, Jaumot J, Tauler R, Alberch J, Ginés S, Barbosa J, Sanz-Nebot V. Metabolic profiling for the identification of huntington biomarkers by on-line solid-phase extraction capillary electrophoresis mass spectrometry combined with advanced data analysis tools. Electrophoresis. PMID 26685060 DOI: 10.1002/Elps.201500378 |
0.317 |
|
| 2015 |
Fernández-Santiago R, Carballo-Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez-Danés A, Vilarrasa-Blasi R, Sánchez-Pla A, Mosquera JL, Soriano J, López-Barneo J, Canals JM, Alberch J, Raya Á, Vila M, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. Embo Molecular Medicine. PMID 26516212 DOI: 10.15252/Emmm.201505439 |
0.581 |
|
| 2015 |
Puigdellívol M, Cherubini M, Brito V, Giralt A, Suelves N, Ballesteros J, Zamora-Moratalla A, Martín ED, Eipper BA, Alberch J, Ginés S. A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease. Human Molecular Genetics. PMID 26464483 DOI: 10.1093/Hmg/Ddv426 |
0.383 |
|
| 2015 |
Straccia M, Garcia-Diaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal PB, Vinh NN, Yung S, Kelly CM, Svendsen CN, Kemp PJ, Arjomand J, Schoenfeld RC, Alberch J, Allen ND, et al. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy. Methods & Clinical Development. 2: 15030. PMID 26417608 DOI: 10.1038/Mtm.2015.30 |
0.626 |
|
| 2015 |
Anglada-Huguet M, Vidal L, Giralt A, García-Díaz Barriga G, Xifró X, Alberch J. Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity. Neurobiology of Disease. PMID 26369879 DOI: 10.1016/J.Nbd.2015.09.001 |
0.415 |
|
| 2015 |
Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular Neurobiology. PMID 26223799 DOI: 10.1007/S12035-015-9335-7 |
0.468 |
|
| 2015 |
Cherubini M, Puigdellívol M, Alberch J, Ginés S. Cdk5-mediated mitochondrial fission: A key player in dopaminergic toxicity in Huntington's disease. Biochimica Et Biophysica Acta. 1852: 2145-60. PMID 26143143 DOI: 10.1016/J.Bbadis.2015.06.025 |
0.313 |
|
| 2015 |
Fernández-Nogales M, Hernández F, Miguez A, Alberch J, Ginés S, Pérez-Navarro E, Lucas JJ. Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease. Human Molecular Genetics. 24: 5040-52. PMID 26082469 DOI: 10.1093/Hmg/Ddv224 |
0.413 |
|
| 2015 |
Miguez A, García-Díaz Barriga G, Brito V, Straccia M, Giralt A, Ginés S, Canals JM, Alberch J. Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation. Human Molecular Genetics. 24: 4958-70. PMID 26063761 DOI: 10.1093/Hmg/Ddv218 |
0.668 |
|
| 2015 |
Martín-Flores N, Romaní-Aumedes J, Rué L, Canal M, Sanders P, Straccia M, Allen ND, Alberch J, Canals JM, Pérez-Navarro E, Malagelada C. RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death. Molecular Neurobiology. PMID 25876513 DOI: 10.1007/S12035-015-9166-6 |
0.704 |
|
| 2015 |
Tyebji S, Saavedra A, Canas PM, Pliassova A, Delgado-García JM, Alberch J, Cunha RA, Gruart A, Pérez-Navarro E. Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease. Neurobiology of Disease. 74: 41-57. PMID 25449908 DOI: 10.1016/J.Nbd.2014.11.004 |
0.411 |
|
| 2014 |
Brito V, Giralt A, Enriquez-Barreto L, PuigdellÃvol M, Suelves N, Zamora-Moratalla A, Ballesteros JJ, MartÃn ED, Dominguez-Iturza N, Morales M, Alberch J, Ginés S. Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction. The Journal of Clinical Investigation. 124: 4411-28. PMID 25180603 DOI: 10.1172/Jci74809 |
0.33 |
|
| 2014 |
Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, et al. Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. Cell Death & Disease. 5: e1364. PMID 25101677 DOI: 10.1038/Cddis.2014.333 |
0.471 |
|
| 2014 |
Moreno B, Lopez I, Fernández-DÃez B, Gottlieb M, Matute C, Sánchez-Gómez MV, Domercq M, Giralt A, Alberch J, Collon KW, Zhang H, Parent JM, Teixido M, Giralt E, Ceña V, et al. Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine. Plos One. 9: e90671. PMID 24599318 DOI: 10.1371/Journal.Pone.0090671 |
0.454 |
|
| 2014 |
Anglada-Huguet M, Xifró X, Giralt A, Zamora-Moratalla A, MartÃn ED, Alberch J. Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease. Molecular Neurobiology. 49: 784-95. PMID 24198227 DOI: 10.1007/S12035-013-8556-X |
0.359 |
|
| 2014 |
Rué L, Alcalá-Vida R, López-Soop G, Creus-Muncunill J, Alberch J, Pérez-Navarro E. Early down-regulation of PKCδ as a pro-survival mechanism in Huntington's disease. Neuromolecular Medicine. 16: 25-37. PMID 23896721 DOI: 10.1007/S12017-013-8248-8 |
0.44 |
|
| 2014 |
Cherubini M, Puigdellivol M, Alberch J, Gines S. B31 Striatal Deregulation Of Cdk5 Alters Mitochondrial Dynamics In Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A20-A20. DOI: 10.1136/Jnnp-2014-309032.59 |
0.413 |
|
| 2014 |
Brito V, Giralt A, Enriquez-Barreto L, Puigdellivol M, Suelves N, Morales M, Martin E, Alberch J, Gines S. B22 Normalisation Of Aberrant P75NTR Levels Prevents Hippocampal Synaptic And Cognitive Deficits And Ameliorates Cortico-striatal Dysfunction In Huntington Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A16-A17. DOI: 10.1136/Jnnp-2014-309032.50 |
0.405 |
|
| 2014 |
Alcala R, Creus-Muncunill J, Azkona G, Alberch J, Perez-Navarro E. B10 Nuclear Lamina Is Differentially Altered In Huntington's Disease Brain Regions Journal of Neurology, Neurosurgery & Psychiatry. 85: A12-A12. DOI: 10.1136/Jnnp-2014-309032.38 |
0.386 |
|
| 2014 |
Canadell M, Moreno-Delgado D, Rodriguez-Ruiz M, Moreno E, Botta J, Gasperini P, Cordomi A, Howell L, Navarro G, Casado V, Ferre S, Guzman M, Pardo L, Alberch J, Canela E, et al. M17 Targeting Dopamine D1-histamine H3 Receptor Heteromers As A Therapeutical Strategy To Prevent Cognitive Deficits And Neurodegeneration In Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A100-A100. DOI: 10.1136/Jnnp-2014-309032.289 |
0.409 |
|
| 2014 |
Saavedra A, Tyebji S, Canas P, Pliassova A, Delgado-Garcia J, Alberch J, Cunha R, Gruart A, Perez-Navarro E. M16 D1R and A2AR Blockade Normalises PKA Activity and Improves Hippocampal-dependent Cognitive Dysfunction but not Motor Deficits in Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A100. DOI: 10.1136/Jnnp-2014-309032.288 |
0.381 |
|
| 2014 |
Miguez A, Garcia G, Brito V, Straccia M, Giralt A, Gines S, Canals J, Alberch J. M15 Fingolimod (FTY720) Enhances Hippocampal Synaptic Plasticity and Memory in Huntington's Disease by Preventing P75NTR/TRKB Imbalance Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.287 |
0.654 |
|
| 2014 |
Diaz Barriga A, Giralt A, Anglada-Huguet M, Canals J, Alberch J. M14 7,8 Dihydroxyflavone Ameliorates Cognitive And Motor Deficits In A Huntingon's Disease Mouse Model Through A Different Activation Profile From Bdnf Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.286 |
0.67 |
|
| 2013 |
Saavedra A, Giralt A, Arumà H, Alberch J, Pérez-Navarro E. Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease. Plos One. 8: e73664. PMID 24040016 DOI: 10.1371/Journal.Pone.0073664 |
0.379 |
|
| 2013 |
Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, ... Alberch J, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8. PMID 23852340 DOI: 10.1038/Nm.3246 |
0.458 |
|
| 2013 |
Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, et al. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Human Molecular Genetics. 22: 3869-82. PMID 23720495 DOI: 10.1093/Hmg/Ddt242 |
0.639 |
|
| 2013 |
Giralt A, Sanchis D, Cherubini M, Ginés S, Cañas X, Comella JX, Alberch J. Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety. Experimental Neurology. 247: 122-9. PMID 23603365 DOI: 10.1016/J.Expneurol.2013.03.028 |
0.378 |
|
| 2013 |
Brito V, PuigdellÃvol M, Giralt A, del Toro D, Alberch J, Ginés S. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. Cell Death & Disease. 4: e595. PMID 23598407 DOI: 10.1038/Cddis.2013.116 |
0.468 |
|
| 2013 |
Giralt A, Saavedra A, Carretón O, Arumà H, Tyebji S, Alberch J, Pérez-Navarro E. PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model. Hippocampus. 23: 684-95. PMID 23576401 DOI: 10.1002/Hipo.22128 |
0.39 |
|
| 2013 |
Barroso E, del Valle J, Porquet D, Vieira Santos AM, Salvadó L, RodrÃguez-RodrÃguez R, Gutiérrez P, Anglada-Huguet M, Alberch J, Camins A, Palomer X, Pallà s M, Michalik L, Wahli W, Vázquez-Carrera M. Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice. Biochimica Et Biophysica Acta. 1832: 1241-8. PMID 23507144 DOI: 10.1016/J.Bbadis.2013.03.006 |
0.37 |
|
| 2013 |
Rué L, López-Soop G, Gelpi E, MartÃnez-Vicente M, Alberch J, Pérez-Navarro E. Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease. Neurobiology of Disease. 52: 219-28. PMID 23295856 DOI: 10.1016/J.Nbd.2012.12.008 |
0.455 |
|
| 2012 |
Giralt A, Saavedra A, Alberch J, Pérez-Navarro E. Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms. Journal of Huntington's Disease. 1: 155-73. PMID 25063329 DOI: 10.3233/Jhd-120023 |
0.371 |
|
| 2012 |
Canela L, Selga E, GarcÃa-MartÃnez JM, Amaral OB, Fernández-Dueñas V, Alberch J, Canela EI, Franco R, Noé V, LluÃs C, Ciudad CJ, Ciruela F. Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene. 508: 199-205. PMID 22892378 DOI: 10.1016/J.Gene.2012.07.074 |
0.396 |
|
| 2012 |
Carretón O, Giralt A, Torres-Peraza JF, Brito V, Lucas JJ, Ginés S, Canals JM, Alberch J. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental Neurology. 237: 335-45. PMID 22776425 DOI: 10.1016/J.Expneurol.2012.06.033 |
0.656 |
|
| 2012 |
Ruiz C, Casarejos MJ, Rubio I, Gines S, Puigdellivol M, Alberch J, Mena MA, de Yebenes JG. The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins. Brain Research. 1459: 100-12. PMID 22560595 DOI: 10.1016/J.Brainres.2012.04.021 |
0.478 |
|
| 2012 |
Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, Jiménez-Delgado S, Caig C, Mora S, Di Guglielmo C, Ezquerra M, Patel B, Giralt A, Canals JM, Memo M, Alberch J, López-Barneo J, Vila M, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. Embo Molecular Medicine. 4: 380-95. PMID 22407749 DOI: 10.1002/Emmm.201200215 |
0.59 |
|
| 2012 |
Anglada-Huguet M, Giralt A, Perez-Navarro E, Alberch J, Xifró X. Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease. Journal of Neurochemistry. 121: 639-48. PMID 22372926 DOI: 10.1111/J.1471-4159.2012.07711.X |
0.37 |
|
| 2012 |
MartÃn-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, MartÃnez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM. Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells and Development. 21: 2239-51. PMID 22142223 DOI: 10.1089/Scd.2011.0607 |
0.667 |
|
| 2012 |
Giralt A, PuigdellÃvol M, Carretón O, Paoletti P, Valero J, Parra-Damas A, Saura CA, Alberch J, Ginés S. Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity. Human Molecular Genetics. 21: 1203-16. PMID 22116937 DOI: 10.1093/Hmg/Ddr552 |
0.341 |
|
| 2011 |
Xifró X, Anglada-Huguet M, Rué L, Saavedra A, Pérez-Navarro E, Alberch J. Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity. Molecular Neurodegeneration. 6: 74. PMID 22041125 DOI: 10.1186/1750-1326-6-74 |
0.36 |
|
| 2011 |
Giralt A, Carretón O, Lao-Peregrin C, Martín ED, Alberch J. Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction. Molecular Neurodegeneration. 6: 71. PMID 21985529 DOI: 10.1186/1750-1326-6-71 |
0.459 |
|
| 2011 |
Giralt A, Saavedra A, Carretón O, Xifró X, Alberch J, Pérez-Navarro E. Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease. Human Molecular Genetics. 20: 4232-47. PMID 21835884 DOI: 10.1093/Hmg/Ddr351 |
0.379 |
|
| 2011 |
Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8150-62. PMID 21632937 DOI: 10.1523/Jneurosci.3446-10.2011 |
0.463 |
|
| 2011 |
Sánchez-Gómez MV, Alberdi E, Pérez-Navarro E, Alberch J, Matute C. Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2996-3006. PMID 21414921 DOI: 10.1523/Jneurosci.5578-10.2011 |
0.323 |
|
| 2011 |
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, ... ... Alberch J, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278 |
0.402 |
|
| 2010 |
Urbán N, MartÃn-Ibáñez R, Herranz C, Esgleas M, Crespo E, Pardo M, Crespo-EnrÃquez I, Méndez-Gómez HR, Waclaw R, Chatzi C, Alvarez S, Alvarez R, Duester G, Campbell K, de Lera AR, ... ... Alberch J, et al. Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling. Neural Development. 5: 21. PMID 20735826 DOI: 10.1186/1749-8104-5-21 |
0.626 |
|
| 2010 |
del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J. Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease. Journal of Neurochemistry. 115: 153-67. PMID 20663016 DOI: 10.1111/J.1471-4159.2010.06912.X |
0.617 |
|
| 2010 |
Giralt A, Friedman HC, Caneda-Ferrón B, Urbán N, Moreno E, Rubio N, Blanco J, Peterson A, Canals JM, Alberch J. BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease. Gene Therapy. 17: 1294-308. PMID 20463759 DOI: 10.1038/Gt.2010.71 |
0.651 |
|
| 2010 |
Ginés S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. The Journal of Biological Chemistry. 285: 21537-48. PMID 20442398 DOI: 10.1074/Jbc.M109.084202 |
0.42 |
|
| 2010 |
Twohig JP, Roberts MI, Gavalda N, Rees-Taylor EL, Giralt A, Adams D, Brooks SP, Bull MJ, Calder CJ, Cuff S, Yong AA, Alberch J, Davies A, Dunnett SB, Tolkovsky AM, et al. Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3782-92. PMID 20220013 DOI: 10.1523/Jneurosci.1928-09.2010 |
0.476 |
|
| 2010 |
Graus F, Boronat A, Xifró X, Boix M, Svigelj V, GarcÃa A, Palomino A, Sabater L, Alberch J, Saiz A. The expanding clinical profile of anti-AMPA receptor encephalitis. Neurology. 74: 857-9. PMID 20211911 DOI: 10.1212/Wnl.0B013E3181D3E404 |
0.324 |
|
| 2010 |
MartÃn-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, MarÃn O, Georgopoulos K, Mengod G, Fariñas I, ... ... Alberch J, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. The Journal of Comparative Neurology. 518: 329-51. PMID 19950118 DOI: 10.1002/Cne.22215 |
0.686 |
|
| 2010 |
Saavedra A, GarcÃa-MartÃnez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, DÃaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum. Cell Death and Differentiation. 17: 324-35. PMID 19745829 DOI: 10.1038/Cdd.2009.127 |
0.654 |
|
| 2010 |
Alberch J, Pérez-Navarro E, Canals JM. Animal Models of Huntington's Disease Encyclopedia of Neuroscience. 429-436. DOI: 10.1016/B978-008045046-9.00502-7 |
0.532 |
|
| 2009 |
Xifró X, Giralt A, Saavedra A, GarcÃa-MartÃnez JM, DÃaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity. Neurobiology of Disease. 36: 461-9. PMID 19733666 DOI: 10.1016/J.Nbd.2009.08.012 |
0.464 |
|
| 2009 |
Sabater L, Giralt A, Boronat A, Hankiewicz K, Blanco Y, Llufriu S, Alberch J, Graus F, Saiz A. Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study. Journal of Neuroimmunology. 215: 31-5. PMID 19695715 DOI: 10.1016/J.Jneuroim.2009.07.014 |
0.313 |
|
| 2009 |
DÃaz-Hernández M, DÃez-Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT, Lucas JJ. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1893-906. PMID 19171786 DOI: 10.1096/Fj.08-122275 |
0.69 |
|
| 2009 |
del Toro D, Alberch J, Lázaro-Diéguez F, MartÃn-Ibáñez R, Xifró X, Egea G, Canals JM. Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus. Molecular Biology of the Cell. 20: 1478-92. PMID 19144827 DOI: 10.1091/Mbc.E08-07-0726 |
0.603 |
|
| 2009 |
Giralt A, Rodrigo T, MartÃn ED, Gonzalez JR, Milà M, Ceña V, Dierssen M, Canals JM, Alberch J. Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression. Neuroscience. 158: 1234-50. PMID 19121372 DOI: 10.1016/J.Neuroscience.2008.11.024 |
0.654 |
|
| 2008 |
Paoletti P, Vila I, Rifé M, Lizcano JM, Alberch J, Ginés S. Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10090-101. PMID 18829967 DOI: 10.1523/Jneurosci.3237-08.2008 |
0.429 |
|
| 2008 |
Sabater L, Xifró X, Saiz A, Alberch J, Graus F. Analysis of antibodies to neuronal surface antigens in adult opsoclonus-myoclonus. Journal of Neuroimmunology. 196: 188-91. PMID 18462809 DOI: 10.1016/J.Jneuroim.2008.03.013 |
0.307 |
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| 2008 |
Gavaldà N, Pérez-Navarro E, GarcÃa-MartÃnez JM, Marco S, Benito A, Alberch J. Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury. Molecular and Cellular Neurosciences. 37: 663-72. PMID 18272391 DOI: 10.1016/J.Mcn.2007.12.013 |
0.388 |
|
| 2008 |
Xifró X, GarcÃa-MartÃnez JM, Del Toro D, Alberch J, Pérez-Navarro E. Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells. Journal of Neurochemistry. 105: 1596-612. PMID 18221365 DOI: 10.1111/J.1471-4159.2008.05252.X |
0.381 |
|
| 2008 |
Torres-Peraza JF, Giralt A, GarcÃa-MartÃnez JM, Pedrosa E, Canals JM, Alberch J. Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling. Neurobiology of Disease. 29: 409-21. PMID 18063376 DOI: 10.1016/J.Nbd.2007.10.003 |
0.664 |
|
| 2007 |
GarcÃa-MartÃnez JM, Pérez-Navarro E, Xifró X, Canals JM, DÃaz-Hernández M, Trioulier Y, Brouillet E, Lucas JJ, Alberch J. BH3-only proteins Bid and Bim(EL) are differentially involved in neuronal dysfunction in mouse models of Huntington's disease. Journal of Neuroscience Research. 85: 2756-69. PMID 17387706 DOI: 10.1002/Jnr.21258 |
0.673 |
|
| 2007 |
MartÃn-Ibáñez R, Urbán N, Sergent-Tanguy S, Pineda JR, Garrido-Clua N, Alberch J, Canals JM. Interplay of leukemia inhibitory factor and retinoic acid on neural differentiation of mouse embryonic stem cells. Journal of Neuroscience Research. 85: 2686-701. PMID 17348039 DOI: 10.1002/Jnr.21228 |
0.638 |
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| 2007 |
Sahún I, Delgado-García JM, Amador-Arjona A, Giralt A, Alberch J, Dierssen M, Gruart A. Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2253-60. PMID 17329422 DOI: 10.1523/Jneurosci.4055-06.2007 |
0.338 |
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| 2007 |
Torres-Peraza J, Pezzi S, Canals JM, Gavaldà N, GarcÃa-MartÃnez JM, Pérez-Navarro E, Alberch J. Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. Neuroscience. 144: 462-71. PMID 17081696 DOI: 10.1016/J.Neuroscience.2006.09.038 |
0.714 |
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| 2007 |
Pineda JR, Rubio N, Akerud P, Urbán N, Badimon L, Arenas E, Alberch J, Blanco J, Canals JM. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells. Gene Therapy. 14: 118-28. PMID 16943855 DOI: 10.1038/Sj.Gt.3302847 |
0.717 |
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| 2006 |
del Toro D, Canals JM, Ginés S, Kojima M, Egea G, Alberch J. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12748-57. PMID 17151278 DOI: 10.1523/Jneurosci.3873-06.2006 |
0.645 |
|
| 2006 |
Dierssen M, Gratacòs M, Sahún I, MartÃn M, Gallego X, Amador-Arjona A, MartÃnez de Lagrán M, Murtra P, Martà E, Pujana MA, Ferrer I, Dalfó E, MartÃnez-Cué C, Flórez J, Torres-Peraza JF, ... Alberch J, et al. Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction. Neurobiology of Disease. 24: 403-18. PMID 16963267 DOI: 10.1016/J.Nbd.2006.07.015 |
0.425 |
|
| 2006 |
Pérez-Navarro E, Canals JM, Ginés S, Alberch J. Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington's disease. Histology and Histopathology. 21: 1217-32. PMID 16874665 |
0.628 |
|
| 2006 |
Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/Jci27607 |
0.679 |
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| 2006 |
Ginés S, Bosch M, Marco S, Gavaldà N, DÃaz-Hernández M, Lucas JJ, Canals JM, Alberch J. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. The European Journal of Neuroscience. 23: 649-58. PMID 16487146 DOI: 10.1111/J.1460-9568.2006.04590.X |
0.764 |
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| 2006 |
GarcÃa-MartÃnez JM, Pérez-Navarro E, Gavaldà N, Alberch J. Glial cell line-derived neurotrophic factor promotes the arborization of cultured striatal neurons through the p42/p44 mitogen-activated protein kinase pathway. Journal of Neuroscience Research. 83: 68-79. PMID 16323212 DOI: 10.1002/Jnr.20713 |
0.41 |
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| 2005 |
DÃaz-Hernández M, Torres-Peraza J, Salvatori-Abarca A, Morán MA, Gómez-Ramos P, Alberch J, Lucas JJ. Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9773-81. PMID 16237181 DOI: 10.1523/Jneurosci.3183-05.2005 |
0.463 |
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| 2005 |
Alberch J, López M, Badenas C, Carrasco JL, Milà M, Muñoz E, Canals JM. Association between BDNF Val66Met polymorphism and age at onset in Huntington disease. Neurology. 65: 964-5. PMID 16186551 DOI: 10.1212/01.Wnl.0000175977.57661.B1 |
0.62 |
|
| 2005 |
Orive G, De Castro M, Ponce S, Hernández RM, Gascón AR, Bosch M, Alberch J, Pedraz JL. Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 283-9. PMID 15935736 DOI: 10.1016/J.Ymthe.2005.04.002 |
0.538 |
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| 2005 |
Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J. Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease. Journal of Neurochemistry. 93: 1057-68. PMID 15934928 DOI: 10.1111/J.1471-4159.2005.03047.X |
0.777 |
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| 2005 |
Pezzi S, Checa N, Alberch J. The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 23: 343-9. PMID 15927758 DOI: 10.1016/J.Ijdevneu.2004.12.007 |
0.428 |
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| 2005 |
Blanco Y, Saiz A, Costa M, Torres-Peraza JF, Carreras E, Alberch J, Jaraquemada D, Graus F. Evolution of brain-derived neurotrophic factor levels after autologous hematopietic stem cell transplantation in multiple sclerosis. Neuroscience Letters. 380: 122-6. PMID 15854763 DOI: 10.1016/J.Neulet.2005.01.032 |
0.364 |
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| 2005 |
Canudas AM, Pezzi S, Canals JM, Pallàs M, Alberch J. Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury. Brain Research. Molecular Brain Research. 134: 147-54. PMID 15790538 DOI: 10.1016/J.Molbrainres.2004.11.012 |
0.698 |
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| 2005 |
Pérez-Navarro E, Gavaldà N, Gratacòs E, Alberch J. Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum. Journal of Neurochemistry. 92: 678-91. PMID 15659237 DOI: 10.1111/J.1471-4159.2004.02904.X |
0.406 |
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| 2004 |
Bosch M, Pineda JR, Suñol C, Petriz J, Cattaneo E, Alberch J, Canals JM. Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease. Experimental Neurology. 190: 42-58. PMID 15473979 DOI: 10.1016/J.Expneurol.2004.06.027 |
0.746 |
|
| 2004 |
Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, MartÃn-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7727-39. PMID 15342740 DOI: 10.1523/Jneurosci.1197-04.2004 |
0.789 |
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| 2004 |
Sieber BA, Kuzmin A, Canals JM, Danielsson A, Paratcha G, Arenas E, Alberch J, Ogren SO, Ibáñez CF. Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Molecular and Cellular Neurosciences. 26: 418-28. PMID 15234346 DOI: 10.1016/J.Mcn.2004.03.009 |
0.722 |
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| 2004 |
Gavaldà N, Pérez-Navarro E, Gratacòs E, Comella JX, Alberch J. Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons. Molecular and Cellular Neurosciences. 25: 460-8. PMID 15033174 DOI: 10.1016/J.Mcn.2003.11.012 |
0.469 |
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| 2004 |
Alberch J, Pérez-Navarro E, Canals JM. Neurotrophic factors in Huntington's disease. Progress in Brain Research. 146: 195-229. PMID 14699966 DOI: 10.1016/S0079-6123(03)46014-7 |
0.703 |
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| 2003 |
Saura J, Parés M, Bové J, Pezzi S, Alberch J, Marin C, Tolosa E, Martà MJ. Intranigral infusion of interleukin-1beta activates astrocytes and protects from subsequent 6-hydroxydopamine neurotoxicity. Journal of Neurochemistry. 85: 651-61. PMID 12694391 |
0.304 |
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| 2003 |
Alberch J, Canals JM, Pérez-Navarro E. Therapeutic strategies in Huntington's disease Expert Opinion On Therapeutic Patents. 13: 449-465. DOI: 10.1517/13543776.13.4.449 |
0.673 |
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| 2002 |
Gratacòs E, Gavaldà N, Alberch J. Bone morphogenetic protein-6 is a neurotrophic factor for calbindin-positive striatal neurons. Journal of Neuroscience Research. 70: 638-44. PMID 12424731 DOI: 10.1002/Jnr.10438 |
0.457 |
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| 2002 |
Marco S, Saura J, Pérez-Navarro E, José Martà M, Tolosa E, Alberch J. Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease. Journal of Neurobiology. 52: 343-51. PMID 12210101 DOI: 10.1002/Neu.10082 |
0.477 |
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| 2002 |
Alberch J, Pérez-Navarro E, Canals JM. Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease. Brain Research Bulletin. 57: 817-22. PMID 12031278 DOI: 10.1016/S0361-9230(01)00775-4 |
0.695 |
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| 2002 |
Marco S, Canudas AM, Canals JM, Gavaldà N, Pérez-Navarro E, Alberch J. Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum. Experimental Neurology. 174: 243-52. PMID 11922665 DOI: 10.1006/Exnr.2001.7859 |
0.671 |
|
| 2002 |
Marco S, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. Journal of Neurobiology. 50: 323-32. PMID 11891666 DOI: 10.1002/Neu.10033 |
0.655 |
|
| 2002 |
Reiriz J, Holm PC, Alberch J, Arenas E. BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors. Journal of Neurobiology. 50: 291-304. PMID 11891664 DOI: 10.1002/Neu.10034 |
0.65 |
|
| 2001 |
Gratacòs E, Checa N, Pérez-Navarro E, Alberch J. Brain-derived neurotrophic factor (BDNF) mediates bone morphogenetic protein-2 (BMP-2) effects on cultured striatal neurones. Journal of Neurochemistry. 79: 747-55. PMID 11723167 DOI: 10.1046/J.1471-4159.2001.00570.X |
0.456 |
|
| 2001 |
Checa N, Canals JM, Gratacòs E, Alberch J. TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia. Experimental Neurology. 172: 282-92. PMID 11716553 DOI: 10.1006/Exnr.2001.7796 |
0.654 |
|
| 2001 |
Gratacòs E, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members. Journal of Neurochemistry. 78: 1287-96. PMID 11579137 DOI: 10.1046/J.1471-4159.2001.00538.X |
0.668 |
|
| 2001 |
Gratacòs E, Checa N, Alberch J. Bone morphogenetic protein-2, but not bone morphogenetic protein-7, promotes dendritic growth and calbindin phenotype in cultured rat striatal neurons. Neuroscience. 104: 783-90. PMID 11440809 DOI: 10.1016/S0306-4522(01)00122-1 |
0.358 |
|
| 2001 |
Canals JM, Checa N, Marco S, Akerud P, Michels A, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 117-24. PMID 11150327 DOI: 10.1523/Jneurosci.21-01-00117.2001 |
0.756 |
|
| 2000 |
Pérez-Navarro E, Canudas AM, Akerund P, Alberch J, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. Journal of Neurochemistry. 75: 2190-9. PMID 11183872 DOI: 10.1046/J.1471-4159.2000.0752190.X |
0.673 |
|
| 2000 |
Checa N, Canals JM, Alberch J. Developmental regulation of BDNF and NT-3 expression by quinolinic acid in the striatum and its main connections. Experimental Neurology. 165: 118-24. PMID 10964490 DOI: 10.1006/Exnr.2000.7451 |
0.676 |
|
| 2000 |
Pérez-Navarro E, Akerud P, Marco S, Canals JM, Tolosa E, Arenas E, Alberch J. Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease. Neuroscience. 98: 89-96. PMID 10858615 DOI: 10.1016/S0306-4522(00)00074-9 |
0.754 |
|
| 2000 |
PavÃa J, Alberch J, Alvárez I, Toledano A, de Ceballos ML. Repeated intracerebroventricular administration of beta-amyloid(25-35) to rats decreases muscarinic receptors in cerebral cortex. Neuroscience Letters. 278: 69-72. PMID 10643803 DOI: 10.1016/S0304-3940(99)00900-3 |
0.36 |
|
| 1999 |
Pérez-Navarro E, Alberch J, Neveu I, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo. Neuroscience. 91: 1257-64. PMID 10391433 DOI: 10.1016/S0306-4522(98)00723-4 |
0.677 |
|
| 1999 |
Akerud P, Alberch J, Eketjäll S, Wagner J, Arenas E. Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. Journal of Neurochemistry. 73: 70-8. PMID 10386956 DOI: 10.1046/J.1471-4159.1999.0730070.X |
0.778 |
|
| 1999 |
Canals JM, Checa N, Marco S, Michels A, Pérez-Navarro E, Alberch J. The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum. Brain Research. Molecular Brain Research. 69: 242-8. PMID 10366745 DOI: 10.1016/S0169-328X(99)00130-8 |
0.645 |
|
| 1999 |
Reiriz J, Espejo M, Ventura F, Ambrosio S, Alberch J. Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons. Journal of Neurobiology. 38: 161-70. PMID 10022564 DOI: 10.1002/(Sici)1097-4695(19990205)38:2<161::Aid-Neu1>3.0.Co;2-3 |
0.418 |
|
| 1999 |
Pérez-Navarro E, Arenas E, Marco S, Alberch J. Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo. The European Journal of Neuroscience. 11: 241-9. PMID 9987028 DOI: 10.1046/J.1460-9568.1999.00433.X |
0.679 |
|
| 1998 |
Canals JM, Marco S, Checa N, Michels A, Pérez-Navarro E, Arenas E, Alberch J. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiology of Disease. 5: 357-64. PMID 10069578 DOI: 10.1006/Nbdi.1998.0211 |
0.746 |
|
| 1998 |
Graus F, Gultekin SH, Ferrer I, Reiriz J, Alberch J, Dalmau J. Localization of the neuronal antigen recognized by anti-Tr antibodies from patients with paraneoplastic cerebellar degeneration and Hodgkin's disease in the rat nervous system. Acta Neuropathologica. 96: 1-7. PMID 9678507 DOI: 10.1007/S004010050853 |
0.373 |
|
| 1998 |
Ferrer I, Ballabriga J, Martà E, Pérez E, Alberch J, Arenas E. BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia. Brain Pathology (Zurich, Switzerland). 8: 253-61. PMID 9546284 DOI: 10.1111/J.1750-3639.1998.Tb00151.X |
0.628 |
|
| 1997 |
Canals JM, Pérez-Navarro E, Ruiz-Avila L, Alberch J, Calvo N, MartÃn-Zanca D, Marsal J. A brain-derived neurotrophic factor (BDNF) related system is involved in the maintenance of the polyinnervate Torpedo electric organ. Neurochemistry International. 31: 33-8. PMID 9185162 DOI: 10.1016/S0197-0186(96)00133-7 |
0.634 |
|
| 1996 |
Calvo N, Reiriz J, Pérez-Navarro E, Alberch J. Tachykinins protect cholinergic neurons from quinolinic acid excitotoxicity in striatal cultures. Brain Research. 740: 323-8. PMID 8973830 DOI: 10.1016/S0006-8993(96)00879-7 |
0.425 |
|
| 1996 |
Pérez-Navarro E, Arenas E, Reiriz J, Calvo N, Alberch J. Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage. Neuroscience. 75: 345-52. PMID 8931001 DOI: 10.1016/0306-4522(96)00336-3 |
0.675 |
|
| 1996 |
van Praag H, Alberch J, Perez-Navarro E, Wu H, Qu PM, Black IB, Dreyfus CF. Unilateral neonatal hippocampal lesion alters septal innervation and trophism of the entorhinal cortex. Experimental Neurology. 141: 130-40. PMID 8797675 DOI: 10.1006/Exnr.1996.0146 |
0.335 |
|
| 1995 |
Pérez-Navarro E, Alberch J. Protective role of nerve growth factor against excitatory amino acid injury during neostriatal cholinergic neurons postnatal development. Experimental Neurology. 135: 146-52. PMID 7589325 DOI: 10.1006/Exnr.1995.1073 |
0.381 |
|
| 1995 |
Mount HT, Dean DO, Alberch J, Dreyfus CF, Black IB. Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9092-6. PMID 7568079 DOI: 10.1073/Pnas.92.20.9092 |
0.462 |
|
| 1994 |
Pérez-Navarro E, Alberch J, Arenas E, Calvo N, Marsal J. Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum. The European Journal of Neuroscience. 6: 706-11. PMID 8075815 DOI: 10.1111/J.1460-9568.1994.Tb00982.X |
0.585 |
|
| 1993 |
Pérez-Navarro E, Alberch J, Arenas E, Marsal J. Nerve growth factor and its receptor are differentially modified by chronic naltrexone treatment during rat brain development. Neuroscience Letters. 149: 47-50. PMID 8469378 DOI: 10.1016/0304-3940(93)90344-K |
0.573 |
|
| 1993 |
Pérez-Navarro E, Alberch J, Marsal J. Postnatal development of functional dopamine, opioid and tachykinin receptors that regulate acetylcholine release from rat neostriatal slices. Effect of 6-hydroxydopamine lesion. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 11: 701-8. PMID 8135128 DOI: 10.1016/0736-5748(93)90059-M |
0.339 |
|
| 1993 |
Arenas E, Pérez-Navarro E, Alberch J, Marsal J. Selective resistance of tachykinin-responsive cholinergic neurons in the quinolinic acid lesioned neostriatum. Brain Research. 603: 317-20. PMID 7681719 DOI: 10.1016/0006-8993(93)91254-P |
0.592 |
|
| 1993 |
Alberch J, Arenas E, Pérez-Navarro E, Marsal J. Control of tachykinin-evoked acetylcholine release from rat striatal slices by dopaminergic neurons. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 445-9. PMID 7509458 DOI: 10.1007/Bf00173201 |
0.568 |
|
| 1991 |
Arenas E, Alberch J, Pérez-Navarro E, Solsona C, Marsal J. Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release. Brain Research. 556: 349-52. PMID 1933369 DOI: 10.1016/0006-8993(91)90329-T |
0.54 |
|
| 1991 |
Arenas E, Alberch J, Marsal J. Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices. Neuroscience. 42: 707-14. PMID 1683474 DOI: 10.1016/0306-4522(91)90039-Q |
0.539 |
|
| 1991 |
Alberch J, Brito B, Notario V, Castro R. Prenatal haloperidol treatment decreases nerve growth factor receptor and mRNA in neonate rat forebrain. Neuroscience Letters. 131: 228-32. PMID 1662344 DOI: 10.1016/0304-3940(91)90620-9 |
0.308 |
|
| 1991 |
Alberch J, Pérez-Navarro E, Arenas E, Marsal J. Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats. Journal of Neurochemistry. 57: 1483-7. PMID 1655975 DOI: 10.1111/J.1471-4159.1991.Tb06342.X |
0.56 |
|
| 1991 |
Arenas E, Alberch J, Perez-Navarro E, Solsona C, Marsal J. Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2332-8. PMID 1651375 DOI: 10.1523/Jneurosci.11-08-02332.1991 |
0.591 |
|
| 1990 |
Alberch J, Arenas E, Sánchez Arroyos R, Marsal J. Excitatory amino acids release endogenous acetylcholine from rat striatal slices: Regulation by gamma-aminobutyric acid. Neurochemistry International. 17: 107-16. PMID 20504609 DOI: 10.1016/0197-0186(90)90074-4 |
0.54 |
|
| 1990 |
Arenas E, Marsal J, Alberch J. GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices. Neuroscience Letters. 120: 201-4. PMID 1981386 DOI: 10.1016/0304-3940(90)90038-B |
0.542 |
|
| 1990 |
Arenas E, Alberch J, Sanchez Arroyos R, Marsal J. Effect of opioids on acetylcholine release evoked by K+ or glutamic acid from rat neostriatal slices. Brain Research. 523: 51-6. PMID 1976420 DOI: 10.1016/0006-8993(90)91633-R |
0.538 |
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