Jordi Alberch - Publications

Universitat de Barcelona, Barcelona, Cataluña, Spain 

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Miguez A, Gomis C, Vila C, Monguió-Tortajada M, Fernández-García S, Bombau G, Galofré M, García-Bravo M, Sanders P, Fernández-Medina H, Poquet B, Salado-Manzano C, Roura S, Alberch J, Segovia JC, et al. Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease. Cellular and Molecular Life Sciences : Cmls. 80: 238. PMID 37535170 DOI: 10.1007/s00018-023-04882-w  0.374
2023 Ballasch I, García-García E, Vila C, Pérez-González A, Sancho-Balsells A, Fernández J, Soto D, Puigdellívol M, Gasull X, Alberch J, Rodríguez MJ, Canals JM, Giralt A. Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration. Brain, Behavior, and Immunity. 109: 144-161. PMID 36702234 DOI: 10.1016/j.bbi.2023.01.016  0.636
2022 Solés-Tarrés I, Cabezas-Llobet N, Lefranc B, Leprince J, Alberch J, Vaudry D, Xifró X. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington's Disease Models: Role of PAC1 Receptor. Frontiers in Pharmacology. 12: 797541. PMID 35153755 DOI: 10.3389/fphar.2021.797541  0.359
2021 Pérez-Sisqués L, Solana-Balaguer J, Campoy-Campos G, Martín-Flores N, Sancho-Balsells A, Vives-Isern M, Soler-Palazón F, Garcia-Forn M, Masana M, Alberch J, Pérez-Navarro E, Giralt A, Malagelada C. RTP801/REDD1 Is Involved in Neuroinflammation and Modulates Cognitive Dysfunction in Huntington's Disease. Biomolecules. 12. PMID 35053183 DOI: 10.3390/biom12010034  0.322
2021 García-García E, Chaparro-Cabanillas N, Coll-Manzano A, Carreras-Caballé M, Giralt A, Del Toro D, Alberch J, Masana M, Rodríguez MJ. Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain. International Journal of Molecular Sciences. 22. PMID 34884823 DOI: 10.3390/ijms222313018  0.364
2021 Pérez-Sisqués L, Sancho-Balsells A, Solana-Balaguer J, Campoy-Campos G, Vives-Isern M, Soler-Palazón F, Anglada-Huguet M, López-Toledano MÁ, Mandelkow EM, Alberch J, Giralt A, Malagelada C. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death & Disease. 12: 616. PMID 34131105 DOI: 10.1038/s41419-021-03899-y  0.322
2021 Pérez-Sisqués L, Sancho-Balsells A, Solana-Balaguer J, Campoy-Campos G, Vives-Isern M, Soler-Palazón F, Anglada-Huguet M, López-Toledano MÁ, Mandelkow EM, Alberch J, Giralt A, Malagelada C. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death & Disease. 12: 616. PMID 34131105 DOI: 10.1038/s41419-021-03899-y  0.322
2021 Pérez-Sisqués L, Martín-Flores N, Masana M, Solana J, Llobet A, Romaní-Aumedes J, Canal M, Campoy G, García-García E, Sánchez-Fernández N, Fernández-García S, Gilbert JP, Rodríguez MJ, Man HY, Feinstein E, ... ... Alberch J, et al. RTP801 regulates motor cortex synaptic transmission and learning. Experimental Neurology. 113755. PMID 33984337 DOI: 10.1016/j.expneurol.2021.113755  0.313
2020 Vidal-Sancho L, Fernández-García S, Solés-Tarrés I, Alberch J, Xifró X. Decreased Myocyte Enhancer Factor 2 Levels in the Hippocampus of Huntington's Disease Mice Are Related to Cognitive Dysfunction. Molecular Neurobiology. PMID 32757160 DOI: 10.1007/S12035-020-02041-X  0.387
2020 Martín-Flores N, Pérez-Sisqués L, Creus-Muncunill J, Masana M, Ginés S, Alberch J, Pérez-Navarro E, Malagelada C. Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease. Cell Death & Disease. 11: 569. PMID 32732871 DOI: 10.1038/S41419-020-02775-5  0.423
2020 Kim A, García-García E, Straccia M, Comella-Bolla A, Miguez A, Masana M, Alberch J, Canals JM, Rodríguez MJ. Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease. Frontiers in Cellular Neuroscience. 14: 163. PMID 32625064 DOI: 10.3389/Fncel.2020.00163  0.671
2020 Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, et al. Modulation of dopamine D receptors via histamine H receptors is a novel therapeutic target for Huntington's disease. Elife. 9. PMID 32513388 DOI: 10.7554/Elife.51093  0.435
2020 Fernández-García S, Sancho-Balsells A, Longueville S, Hervé D, Gruart A, Delgado-García JM, Alberch J, Giralt A. Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy. Cell Death & Disease. 11: 411. PMID 32483154 DOI: 10.1038/S41419-020-2615-9  0.46
2020 Sancho-Balsells A, Brito V, Fernández B, Pardo M, Straccia M, Ginés S, Alberch J, Hernández I, Arranz B, Canals JM, Giralt A. Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1. Frontiers in Cellular Neuroscience. 14: 93. PMID 32477064 DOI: 10.3389/Fncel.2020.00093  0.678
2020 Fernández-García S, Orlandi JG, García-Díaz Barriga GA, Rodríguez MJ, Masana M, Soriano J, Alberch J. Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington's disease. Bmc Biology. 18: 58. PMID 32466798 DOI: 10.1186/S12915-020-00794-4  0.337
2020 Comella-Bolla A, Orlandi JG, Miguez A, Straccia M, García-Bravo M, Bombau G, Galofré M, Sanders P, Carrere J, Segovia JC, Blasi J, Allen ND, Alberch J, Soriano J, Canals JM. Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation. Molecular Neurobiology. PMID 32356172 DOI: 10.1007/S12035-020-01907-4  0.675
2020 Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, et al. Author response: Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease Elife. DOI: 10.7554/Elife.51093.Sa2  0.302
2019 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martín-Ibáñez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, García-Torralba A, Pascual M, Pumarola M, Alberch J, Ginés S, et al. Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Experimental Neurology. 113095. PMID 31712124 DOI: 10.1016/J.Expneurol.2019.113095  0.622
2019 Creus-Muncunill J, Badillos-Rodríguez R, Garcia-Forn M, Masana M, Garcia-Díaz Barriga G, Guisado-Corcoll A, Alberch J, Malagelada C, Delgado-García JM, Gruart A, Pérez-Navarro E. Increased translation as a novel pathogenic mechanism in Huntington's disease. Brain : a Journal of Neurology. PMID 31365052 DOI: 10.1093/Brain/Awz230  0.426
2019 de Pins B, Cifuentes-Díaz C, Thamila Farah A, López-Molina L, Montalban E, Sancho-Balsells A, López A, Ginés S, Delgado-García JM, Alberch J, Gruart A, Girault JA, Giralt A. Conditional BDNF delivery from astrocytes rescues memory deficits, spine density and synaptic properties in the 5xFAD mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30700530 DOI: 10.1523/Jneurosci.2121-18.2019  0.439
2019 Montalban E, Al-Massadi O, Sancho-Balsells A, Brito V, de Pins B, Alberch J, Ginés S, Girault JA, Giralt A. Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes. Translational Psychiatry. 9: 3. PMID 30664624 DOI: 10.1038/S41398-018-0352-Y  0.337
2019 Rodríguez-Urgellés E, Fernández-García S, Orlandi J, Barriga GG, Rodríguez M, Soriano J, Alberch J, Masana M. Brain-derived neurotrophic factor modulates neuronal network structure and dynamics in striatal cultures: Implications for Huntington's disease European Neuropsychopharmacology. 29: S160-S161. DOI: 10.1016/J.Euroneuro.2018.11.280  0.403
2018 Blázquez G, Castañé A, Saavedra A, Masana M, Alberch J, Pérez-Navarro E. Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase. Frontiers in Behavioral Neuroscience. 12: 317. PMID 30760987 DOI: 10.3389/Fnbeh.2018.00317  0.303
2018 García-Forn M, Martínez-Torres S, García-Díaz Barriga G, Alberch J, Milà M, Azkona G, Pérez-Navarro E. Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease. Neurobiology of Disease. 120: 88-97. PMID 30176350 DOI: 10.1016/J.Nbd.2018.08.024  0.376
2018 Saavedra A, Ballesteros JJ, Tyebji S, Martínez-Torres S, Blázquez G, López-Hidalgo R, Azkona G, Alberch J, Martín ED, Pérez-Navarro E. Proteolytic Degradation of Hippocampal STEP in LTP and Learning. Molecular Neurobiology. PMID 29948948 DOI: 10.1007/S12035-018-1170-1  0.368
2018 Cabezas-Llobet N, Camprubí S, García B, Alberch J, Xifró X. Human alpha 1-antitrypsin protects neurons and glial cells against oxygen and glucose deprivation through inhibition of interleukins expression. Biochimica Et Biophysica Acta. PMID 29857082 DOI: 10.1016/J.Bbagen.2018.05.017  0.365
2018 Suelves N, Miguez A, López-Benito S, Barriga GG, Giralt A, Alvarez-Periel E, Arévalo JC, Alberch J, Ginés S, Brito V. Early Downregulation of p75 by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice. Molecular Neurobiology. PMID 29804232 DOI: 10.1007/S12035-018-1126-5  0.465
2018 Saavedra A, García-Díaz Barriga G, Pérez-Navarro E, Alberch J. Huntington's disease: novel therapeutic perspectives hanging in the balance. Expert Opinion On Therapeutic Targets. 1-15. PMID 29671352 DOI: 10.1080/14728222.2018.1465930  0.423
2018 Cabezas-Llobet N, Vidal-Sancho L, Masana M, Fournier A, Alberch J, Vaudry D, Xifró X. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Enhances Hippocampal Synaptic Plasticity and Improves Memory Performance in Huntington's Disease. Molecular Neurobiology. 55: 8263-8277. PMID 29526016 DOI: 10.1007/S12035-018-0972-5  0.395
2018 Creus-Muncunill J, Rué L, Alcalá-Vida R, Badillos-Rodríguez R, Romaní-Aumedes J, Marco S, Alberch J, Perez-Otaño I, Malagelada C, Pérez-Navarro E. Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration. Molecular Neurobiology. PMID 29460266 DOI: 10.1007/S12035-018-0956-5  0.505
2017 Alvarez-Periel E, Puigdellívol M, Brito V, Plattner F, Bibb JA, Alberch J, Ginés S. Cdk5 Contributes to Huntington's Disease Learning and Memory Deficits via Modulation of Brain Region-Specific Substrates. Molecular Neurobiology. PMID 29288339 DOI: 10.1007/S12035-017-0828-4  0.317
2017 Cases S, Saavedra A, Tyebji S, Giralt A, Alberch J, Pérez-Navarro E. Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF. Molecular and Cellular Neurosciences. PMID 29122705 DOI: 10.1016/J.Mcn.2017.11.003  0.405
2017 Giralt A, Gómez-Climent MÁ, Alcalá R, Bretin S, Bertrand D, María Delgado-García J, Pérez-Navarro E, Alberch J, Gruart A. The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice. Neuropharmacology. PMID 28603025 DOI: 10.1016/J.Neuropharm.2017.06.009  0.352
2017 Giralt A, Brito V, Chevy Q, Simonnet C, Otsu Y, Cifuentes-Díaz C, de Pins B, Coura R, Alberch J, Ginés S, Poncer JC, Girault JA. Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model. Nature Communications. 8: 15592. PMID 28555636 DOI: 10.1038/Ncomms15592  0.422
2017 García-Díaz Barriga G, Giralt A, Anglada-Huguet M, Gaja-Capdevila N, Orlandi JG, Soriano J, Canals JM, Alberch J. 7,8 Dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway. Human Molecular Genetics. PMID 28541476 DOI: 10.1093/Hmg/Ddx198  0.471
2017 Martín-Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Barriga GG, Edel MJ, Vicario-Abejón C, Alberch J, Girault JA, Chan S, Kastner P, et al. Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development (Cambridge, England). PMID 28289129 DOI: 10.1242/Dev.138248  0.686
2017 Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E. Chelerythrine promotes Ca(2+)-dependent calpain activation in neuronal cells in a PKC-independent manner. Biochimica Et Biophysica Acta. PMID 28130160 DOI: 10.1016/J.Bbagen.2017.01.021  0.386
2017 Moreno B, Vila G, Fernandez-Diez B, Vázquez R, Penta Ad, Errea O, Escala N, Miguez A, Alberch J, Villoslada P. Methylthioadenosine promotes remyelination by inducing oligodendrocyte differentiation Multiple Sclerosis and Demyelinating Disorders. 2: 1-13. DOI: 10.1186/S40893-017-0020-8  0.326
2016 Canal M, Martín-Flores N, Pérez-Sisqués L, Romaní-Aumedes J, Altas B, Man HY, Kawabe H, Alberch J, Malagelada C. Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease. Oncotarget. PMID 27494837 DOI: 10.18632/Oncotarget.11020  0.426
2016 Anglada-Huguet M, Giralt A, Rué L, Alberch J, Xifró X. Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease. Biochimica Et Biophysica Acta. PMID 27063456 DOI: 10.1016/J.Bbadis.2016.04.002  0.453
2015 Pont L, Benavente F, Jaumot J, Tauler R, Alberch J, Ginés S, Barbosa J, Sanz-Nebot V. Metabolic profiling for the identification of huntington biomarkers by on-line solid-phase extraction capillary electrophoresis mass spectrometry combined with advanced data analysis tools. Electrophoresis. PMID 26685060 DOI: 10.1002/Elps.201500378  0.317
2015 Fernández-Santiago R, Carballo-Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez-Danés A, Vilarrasa-Blasi R, Sánchez-Pla A, Mosquera JL, Soriano J, López-Barneo J, Canals JM, Alberch J, Raya Á, Vila M, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. Embo Molecular Medicine. PMID 26516212 DOI: 10.15252/Emmm.201505439  0.581
2015 Puigdellívol M, Cherubini M, Brito V, Giralt A, Suelves N, Ballesteros J, Zamora-Moratalla A, Martín ED, Eipper BA, Alberch J, Ginés S. A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease. Human Molecular Genetics. PMID 26464483 DOI: 10.1093/Hmg/Ddv426  0.383
2015 Straccia M, Garcia-Diaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal PB, Vinh NN, Yung S, Kelly CM, Svendsen CN, Kemp PJ, Arjomand J, Schoenfeld RC, Alberch J, Allen ND, et al. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy. Methods & Clinical Development. 2: 15030. PMID 26417608 DOI: 10.1038/Mtm.2015.30  0.626
2015 Anglada-Huguet M, Vidal L, Giralt A, García-Díaz Barriga G, Xifró X, Alberch J. Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity. Neurobiology of Disease. PMID 26369879 DOI: 10.1016/J.Nbd.2015.09.001  0.415
2015 Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular Neurobiology. PMID 26223799 DOI: 10.1007/S12035-015-9335-7  0.468
2015 Cherubini M, Puigdellívol M, Alberch J, Ginés S. Cdk5-mediated mitochondrial fission: A key player in dopaminergic toxicity in Huntington's disease. Biochimica Et Biophysica Acta. 1852: 2145-60. PMID 26143143 DOI: 10.1016/J.Bbadis.2015.06.025  0.313
2015 Fernández-Nogales M, Hernández F, Miguez A, Alberch J, Ginés S, Pérez-Navarro E, Lucas JJ. Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease. Human Molecular Genetics. 24: 5040-52. PMID 26082469 DOI: 10.1093/Hmg/Ddv224  0.413
2015 Miguez A, García-Díaz Barriga G, Brito V, Straccia M, Giralt A, Ginés S, Canals JM, Alberch J. Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation. Human Molecular Genetics. 24: 4958-70. PMID 26063761 DOI: 10.1093/Hmg/Ddv218  0.668
2015 Martín-Flores N, Romaní-Aumedes J, Rué L, Canal M, Sanders P, Straccia M, Allen ND, Alberch J, Canals JM, Pérez-Navarro E, Malagelada C. RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death. Molecular Neurobiology. PMID 25876513 DOI: 10.1007/S12035-015-9166-6  0.704
2015 Tyebji S, Saavedra A, Canas PM, Pliassova A, Delgado-García JM, Alberch J, Cunha RA, Gruart A, Pérez-Navarro E. Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease. Neurobiology of Disease. 74: 41-57. PMID 25449908 DOI: 10.1016/J.Nbd.2014.11.004  0.411
2014 Brito V, Giralt A, Enriquez-Barreto L, Puigdellívol M, Suelves N, Zamora-Moratalla A, Ballesteros JJ, Martín ED, Dominguez-Iturza N, Morales M, Alberch J, Ginés S. Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction. The Journal of Clinical Investigation. 124: 4411-28. PMID 25180603 DOI: 10.1172/Jci74809  0.33
2014 Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, et al. Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. Cell Death & Disease. 5: e1364. PMID 25101677 DOI: 10.1038/Cddis.2014.333  0.471
2014 Moreno B, Lopez I, Fernández-Díez B, Gottlieb M, Matute C, Sánchez-Gómez MV, Domercq M, Giralt A, Alberch J, Collon KW, Zhang H, Parent JM, Teixido M, Giralt E, Ceña V, et al. Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine. Plos One. 9: e90671. PMID 24599318 DOI: 10.1371/Journal.Pone.0090671  0.454
2014 Anglada-Huguet M, Xifró X, Giralt A, Zamora-Moratalla A, Martín ED, Alberch J. Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease. Molecular Neurobiology. 49: 784-95. PMID 24198227 DOI: 10.1007/S12035-013-8556-X  0.359
2014 Rué L, Alcalá-Vida R, López-Soop G, Creus-Muncunill J, Alberch J, Pérez-Navarro E. Early down-regulation of PKCδ as a pro-survival mechanism in Huntington's disease. Neuromolecular Medicine. 16: 25-37. PMID 23896721 DOI: 10.1007/S12017-013-8248-8  0.44
2014 Cherubini M, Puigdellivol M, Alberch J, Gines S. B31 Striatal Deregulation Of Cdk5 Alters Mitochondrial Dynamics In Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A20-A20. DOI: 10.1136/Jnnp-2014-309032.59  0.413
2014 Brito V, Giralt A, Enriquez-Barreto L, Puigdellivol M, Suelves N, Morales M, Martin E, Alberch J, Gines S. B22 Normalisation Of Aberrant P75NTR Levels Prevents Hippocampal Synaptic And Cognitive Deficits And Ameliorates Cortico-striatal Dysfunction In Huntington Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A16-A17. DOI: 10.1136/Jnnp-2014-309032.50  0.405
2014 Alcala R, Creus-Muncunill J, Azkona G, Alberch J, Perez-Navarro E. B10 Nuclear Lamina Is Differentially Altered In Huntington's Disease Brain Regions Journal of Neurology, Neurosurgery & Psychiatry. 85: A12-A12. DOI: 10.1136/Jnnp-2014-309032.38  0.386
2014 Canadell M, Moreno-Delgado D, Rodriguez-Ruiz M, Moreno E, Botta J, Gasperini P, Cordomi A, Howell L, Navarro G, Casado V, Ferre S, Guzman M, Pardo L, Alberch J, Canela E, et al. M17 Targeting Dopamine D1-histamine H3 Receptor Heteromers As A Therapeutical Strategy To Prevent Cognitive Deficits And Neurodegeneration In Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A100-A100. DOI: 10.1136/Jnnp-2014-309032.289  0.409
2014 Saavedra A, Tyebji S, Canas P, Pliassova A, Delgado-Garcia J, Alberch J, Cunha R, Gruart A, Perez-Navarro E. M16 D1R and A2AR Blockade Normalises PKA Activity and Improves Hippocampal-dependent Cognitive Dysfunction but not Motor Deficits in Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A100. DOI: 10.1136/Jnnp-2014-309032.288  0.381
2014 Miguez A, Garcia G, Brito V, Straccia M, Giralt A, Gines S, Canals J, Alberch J. M15 Fingolimod (FTY720) Enhances Hippocampal Synaptic Plasticity and Memory in Huntington's Disease by Preventing P75NTR/TRKB Imbalance Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.287  0.654
2014 Diaz Barriga A, Giralt A, Anglada-Huguet M, Canals J, Alberch J. M14 7,8 Dihydroxyflavone Ameliorates Cognitive And Motor Deficits In A Huntingon's Disease Mouse Model Through A Different Activation Profile From Bdnf Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.286  0.67
2013 Saavedra A, Giralt A, Arumí H, Alberch J, Pérez-Navarro E. Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease. Plos One. 8: e73664. PMID 24040016 DOI: 10.1371/Journal.Pone.0073664  0.379
2013 Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, ... Alberch J, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8. PMID 23852340 DOI: 10.1038/Nm.3246  0.458
2013 Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, et al. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Human Molecular Genetics. 22: 3869-82. PMID 23720495 DOI: 10.1093/Hmg/Ddt242  0.639
2013 Giralt A, Sanchis D, Cherubini M, Ginés S, Cañas X, Comella JX, Alberch J. Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety. Experimental Neurology. 247: 122-9. PMID 23603365 DOI: 10.1016/J.Expneurol.2013.03.028  0.378
2013 Brito V, Puigdellívol M, Giralt A, del Toro D, Alberch J, Ginés S. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. Cell Death & Disease. 4: e595. PMID 23598407 DOI: 10.1038/Cddis.2013.116  0.468
2013 Giralt A, Saavedra A, Carretón O, Arumí H, Tyebji S, Alberch J, Pérez-Navarro E. PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model. Hippocampus. 23: 684-95. PMID 23576401 DOI: 10.1002/Hipo.22128  0.39
2013 Barroso E, del Valle J, Porquet D, Vieira Santos AM, Salvadó L, Rodríguez-Rodríguez R, Gutiérrez P, Anglada-Huguet M, Alberch J, Camins A, Palomer X, Pallàs M, Michalik L, Wahli W, Vázquez-Carrera M. Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice. Biochimica Et Biophysica Acta. 1832: 1241-8. PMID 23507144 DOI: 10.1016/J.Bbadis.2013.03.006  0.37
2013 Rué L, López-Soop G, Gelpi E, Martínez-Vicente M, Alberch J, Pérez-Navarro E. Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease. Neurobiology of Disease. 52: 219-28. PMID 23295856 DOI: 10.1016/J.Nbd.2012.12.008  0.455
2012 Giralt A, Saavedra A, Alberch J, Pérez-Navarro E. Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms. Journal of Huntington's Disease. 1: 155-73. PMID 25063329 DOI: 10.3233/Jhd-120023  0.371
2012 Canela L, Selga E, García-Martínez JM, Amaral OB, Fernández-Dueñas V, Alberch J, Canela EI, Franco R, Noé V, Lluís C, Ciudad CJ, Ciruela F. Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene. 508: 199-205. PMID 22892378 DOI: 10.1016/J.Gene.2012.07.074  0.396
2012 Carretón O, Giralt A, Torres-Peraza JF, Brito V, Lucas JJ, Ginés S, Canals JM, Alberch J. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental Neurology. 237: 335-45. PMID 22776425 DOI: 10.1016/J.Expneurol.2012.06.033  0.656
2012 Ruiz C, Casarejos MJ, Rubio I, Gines S, Puigdellivol M, Alberch J, Mena MA, de Yebenes JG. The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins. Brain Research. 1459: 100-12. PMID 22560595 DOI: 10.1016/J.Brainres.2012.04.021  0.478
2012 Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, Jiménez-Delgado S, Caig C, Mora S, Di Guglielmo C, Ezquerra M, Patel B, Giralt A, Canals JM, Memo M, Alberch J, López-Barneo J, Vila M, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. Embo Molecular Medicine. 4: 380-95. PMID 22407749 DOI: 10.1002/Emmm.201200215  0.59
2012 Anglada-Huguet M, Giralt A, Perez-Navarro E, Alberch J, Xifró X. Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease. Journal of Neurochemistry. 121: 639-48. PMID 22372926 DOI: 10.1111/J.1471-4159.2012.07711.X  0.37
2012 Martín-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martínez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM. Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells and Development. 21: 2239-51. PMID 22142223 DOI: 10.1089/Scd.2011.0607  0.667
2012 Giralt A, Puigdellívol M, Carretón O, Paoletti P, Valero J, Parra-Damas A, Saura CA, Alberch J, Ginés S. Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity. Human Molecular Genetics. 21: 1203-16. PMID 22116937 DOI: 10.1093/Hmg/Ddr552  0.341
2011 Xifró X, Anglada-Huguet M, Rué L, Saavedra A, Pérez-Navarro E, Alberch J. Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity. Molecular Neurodegeneration. 6: 74. PMID 22041125 DOI: 10.1186/1750-1326-6-74  0.36
2011 Giralt A, Carretón O, Lao-Peregrin C, Martín ED, Alberch J. Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction. Molecular Neurodegeneration. 6: 71. PMID 21985529 DOI: 10.1186/1750-1326-6-71  0.459
2011 Giralt A, Saavedra A, Carretón O, Xifró X, Alberch J, Pérez-Navarro E. Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease. Human Molecular Genetics. 20: 4232-47. PMID 21835884 DOI: 10.1093/Hmg/Ddr351  0.379
2011 Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8150-62. PMID 21632937 DOI: 10.1523/Jneurosci.3446-10.2011  0.463
2011 Sánchez-Gómez MV, Alberdi E, Pérez-Navarro E, Alberch J, Matute C. Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2996-3006. PMID 21414921 DOI: 10.1523/Jneurosci.5578-10.2011  0.323
2011 Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, ... ... Alberch J, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278  0.402
2010 Urbán N, Martín-Ibáñez R, Herranz C, Esgleas M, Crespo E, Pardo M, Crespo-Enríquez I, Méndez-Gómez HR, Waclaw R, Chatzi C, Alvarez S, Alvarez R, Duester G, Campbell K, de Lera AR, ... ... Alberch J, et al. Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling. Neural Development. 5: 21. PMID 20735826 DOI: 10.1186/1749-8104-5-21  0.626
2010 del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J. Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease. Journal of Neurochemistry. 115: 153-67. PMID 20663016 DOI: 10.1111/J.1471-4159.2010.06912.X  0.617
2010 Giralt A, Friedman HC, Caneda-Ferrón B, Urbán N, Moreno E, Rubio N, Blanco J, Peterson A, Canals JM, Alberch J. BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease. Gene Therapy. 17: 1294-308. PMID 20463759 DOI: 10.1038/Gt.2010.71  0.651
2010 Ginés S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. The Journal of Biological Chemistry. 285: 21537-48. PMID 20442398 DOI: 10.1074/Jbc.M109.084202  0.42
2010 Twohig JP, Roberts MI, Gavalda N, Rees-Taylor EL, Giralt A, Adams D, Brooks SP, Bull MJ, Calder CJ, Cuff S, Yong AA, Alberch J, Davies A, Dunnett SB, Tolkovsky AM, et al. Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3782-92. PMID 20220013 DOI: 10.1523/Jneurosci.1928-09.2010  0.476
2010 Graus F, Boronat A, Xifró X, Boix M, Svigelj V, García A, Palomino A, Sabater L, Alberch J, Saiz A. The expanding clinical profile of anti-AMPA receptor encephalitis. Neurology. 74: 857-9. PMID 20211911 DOI: 10.1212/Wnl.0B013E3181D3E404  0.324
2010 Martín-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, Marín O, Georgopoulos K, Mengod G, Fariñas I, ... ... Alberch J, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. The Journal of Comparative Neurology. 518: 329-51. PMID 19950118 DOI: 10.1002/Cne.22215  0.686
2010 Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum. Cell Death and Differentiation. 17: 324-35. PMID 19745829 DOI: 10.1038/Cdd.2009.127  0.654
2010 Alberch J, Pérez-Navarro E, Canals JM. Animal Models of Huntington's Disease Encyclopedia of Neuroscience. 429-436. DOI: 10.1016/B978-008045046-9.00502-7  0.532
2009 Xifró X, Giralt A, Saavedra A, García-Martínez JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity. Neurobiology of Disease. 36: 461-9. PMID 19733666 DOI: 10.1016/J.Nbd.2009.08.012  0.464
2009 Sabater L, Giralt A, Boronat A, Hankiewicz K, Blanco Y, Llufriu S, Alberch J, Graus F, Saiz A. Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study. Journal of Neuroimmunology. 215: 31-5. PMID 19695715 DOI: 10.1016/J.Jneuroim.2009.07.014  0.313
2009 Díaz-Hernández M, Díez-Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT, Lucas JJ. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1893-906. PMID 19171786 DOI: 10.1096/Fj.08-122275  0.69
2009 del Toro D, Alberch J, Lázaro-Diéguez F, Martín-Ibáñez R, Xifró X, Egea G, Canals JM. Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus. Molecular Biology of the Cell. 20: 1478-92. PMID 19144827 DOI: 10.1091/Mbc.E08-07-0726  0.603
2009 Giralt A, Rodrigo T, Martín ED, Gonzalez JR, Milà M, Ceña V, Dierssen M, Canals JM, Alberch J. Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression. Neuroscience. 158: 1234-50. PMID 19121372 DOI: 10.1016/J.Neuroscience.2008.11.024  0.654
2008 Paoletti P, Vila I, Rifé M, Lizcano JM, Alberch J, Ginés S. Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10090-101. PMID 18829967 DOI: 10.1523/Jneurosci.3237-08.2008  0.429
2008 Sabater L, Xifró X, Saiz A, Alberch J, Graus F. Analysis of antibodies to neuronal surface antigens in adult opsoclonus-myoclonus. Journal of Neuroimmunology. 196: 188-91. PMID 18462809 DOI: 10.1016/J.Jneuroim.2008.03.013  0.307
2008 Gavaldà N, Pérez-Navarro E, García-Martínez JM, Marco S, Benito A, Alberch J. Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury. Molecular and Cellular Neurosciences. 37: 663-72. PMID 18272391 DOI: 10.1016/J.Mcn.2007.12.013  0.388
2008 Xifró X, García-Martínez JM, Del Toro D, Alberch J, Pérez-Navarro E. Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells. Journal of Neurochemistry. 105: 1596-612. PMID 18221365 DOI: 10.1111/J.1471-4159.2008.05252.X  0.381
2008 Torres-Peraza JF, Giralt A, García-Martínez JM, Pedrosa E, Canals JM, Alberch J. Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling. Neurobiology of Disease. 29: 409-21. PMID 18063376 DOI: 10.1016/J.Nbd.2007.10.003  0.664
2007 García-Martínez JM, Pérez-Navarro E, Xifró X, Canals JM, Díaz-Hernández M, Trioulier Y, Brouillet E, Lucas JJ, Alberch J. BH3-only proteins Bid and Bim(EL) are differentially involved in neuronal dysfunction in mouse models of Huntington's disease. Journal of Neuroscience Research. 85: 2756-69. PMID 17387706 DOI: 10.1002/Jnr.21258  0.673
2007 Martín-Ibáñez R, Urbán N, Sergent-Tanguy S, Pineda JR, Garrido-Clua N, Alberch J, Canals JM. Interplay of leukemia inhibitory factor and retinoic acid on neural differentiation of mouse embryonic stem cells. Journal of Neuroscience Research. 85: 2686-701. PMID 17348039 DOI: 10.1002/Jnr.21228  0.638
2007 Sahún I, Delgado-García JM, Amador-Arjona A, Giralt A, Alberch J, Dierssen M, Gruart A. Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2253-60. PMID 17329422 DOI: 10.1523/Jneurosci.4055-06.2007  0.338
2007 Torres-Peraza J, Pezzi S, Canals JM, Gavaldà N, García-Martínez JM, Pérez-Navarro E, Alberch J. Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. Neuroscience. 144: 462-71. PMID 17081696 DOI: 10.1016/J.Neuroscience.2006.09.038  0.714
2007 Pineda JR, Rubio N, Akerud P, Urbán N, Badimon L, Arenas E, Alberch J, Blanco J, Canals JM. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells. Gene Therapy. 14: 118-28. PMID 16943855 DOI: 10.1038/Sj.Gt.3302847  0.717
2006 del Toro D, Canals JM, Ginés S, Kojima M, Egea G, Alberch J. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12748-57. PMID 17151278 DOI: 10.1523/Jneurosci.3873-06.2006  0.645
2006 Dierssen M, Gratacòs M, Sahún I, Martín M, Gallego X, Amador-Arjona A, Martínez de Lagrán M, Murtra P, Martí E, Pujana MA, Ferrer I, Dalfó E, Martínez-Cué C, Flórez J, Torres-Peraza JF, ... Alberch J, et al. Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction. Neurobiology of Disease. 24: 403-18. PMID 16963267 DOI: 10.1016/J.Nbd.2006.07.015  0.425
2006 Pérez-Navarro E, Canals JM, Ginés S, Alberch J. Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington's disease. Histology and Histopathology. 21: 1217-32. PMID 16874665  0.628
2006 Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/Jci27607  0.679
2006 Ginés S, Bosch M, Marco S, Gavaldà N, Díaz-Hernández M, Lucas JJ, Canals JM, Alberch J. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. The European Journal of Neuroscience. 23: 649-58. PMID 16487146 DOI: 10.1111/J.1460-9568.2006.04590.X  0.764
2006 García-Martínez JM, Pérez-Navarro E, Gavaldà N, Alberch J. Glial cell line-derived neurotrophic factor promotes the arborization of cultured striatal neurons through the p42/p44 mitogen-activated protein kinase pathway. Journal of Neuroscience Research. 83: 68-79. PMID 16323212 DOI: 10.1002/Jnr.20713  0.41
2005 Díaz-Hernández M, Torres-Peraza J, Salvatori-Abarca A, Morán MA, Gómez-Ramos P, Alberch J, Lucas JJ. Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9773-81. PMID 16237181 DOI: 10.1523/Jneurosci.3183-05.2005  0.463
2005 Alberch J, López M, Badenas C, Carrasco JL, Milà M, Muñoz E, Canals JM. Association between BDNF Val66Met polymorphism and age at onset in Huntington disease. Neurology. 65: 964-5. PMID 16186551 DOI: 10.1212/01.Wnl.0000175977.57661.B1  0.62
2005 Orive G, De Castro M, Ponce S, Hernández RM, Gascón AR, Bosch M, Alberch J, Pedraz JL. Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 283-9. PMID 15935736 DOI: 10.1016/J.Ymthe.2005.04.002  0.538
2005 Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J. Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease. Journal of Neurochemistry. 93: 1057-68. PMID 15934928 DOI: 10.1111/J.1471-4159.2005.03047.X  0.777
2005 Pezzi S, Checa N, Alberch J. The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 23: 343-9. PMID 15927758 DOI: 10.1016/J.Ijdevneu.2004.12.007  0.428
2005 Blanco Y, Saiz A, Costa M, Torres-Peraza JF, Carreras E, Alberch J, Jaraquemada D, Graus F. Evolution of brain-derived neurotrophic factor levels after autologous hematopietic stem cell transplantation in multiple sclerosis. Neuroscience Letters. 380: 122-6. PMID 15854763 DOI: 10.1016/J.Neulet.2005.01.032  0.364
2005 Canudas AM, Pezzi S, Canals JM, Pallàs M, Alberch J. Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury. Brain Research. Molecular Brain Research. 134: 147-54. PMID 15790538 DOI: 10.1016/J.Molbrainres.2004.11.012  0.698
2005 Pérez-Navarro E, Gavaldà N, Gratacòs E, Alberch J. Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum. Journal of Neurochemistry. 92: 678-91. PMID 15659237 DOI: 10.1111/J.1471-4159.2004.02904.X  0.406
2004 Bosch M, Pineda JR, Suñol C, Petriz J, Cattaneo E, Alberch J, Canals JM. Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease. Experimental Neurology. 190: 42-58. PMID 15473979 DOI: 10.1016/J.Expneurol.2004.06.027  0.746
2004 Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7727-39. PMID 15342740 DOI: 10.1523/Jneurosci.1197-04.2004  0.789
2004 Sieber BA, Kuzmin A, Canals JM, Danielsson A, Paratcha G, Arenas E, Alberch J, Ogren SO, Ibáñez CF. Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Molecular and Cellular Neurosciences. 26: 418-28. PMID 15234346 DOI: 10.1016/J.Mcn.2004.03.009  0.722
2004 Gavaldà N, Pérez-Navarro E, Gratacòs E, Comella JX, Alberch J. Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons. Molecular and Cellular Neurosciences. 25: 460-8. PMID 15033174 DOI: 10.1016/J.Mcn.2003.11.012  0.469
2004 Alberch J, Pérez-Navarro E, Canals JM. Neurotrophic factors in Huntington's disease. Progress in Brain Research. 146: 195-229. PMID 14699966 DOI: 10.1016/S0079-6123(03)46014-7  0.703
2003 Saura J, Parés M, Bové J, Pezzi S, Alberch J, Marin C, Tolosa E, Martí MJ. Intranigral infusion of interleukin-1beta activates astrocytes and protects from subsequent 6-hydroxydopamine neurotoxicity. Journal of Neurochemistry. 85: 651-61. PMID 12694391  0.304
2003 Alberch J, Canals JM, Pérez-Navarro E. Therapeutic strategies in Huntington's disease Expert Opinion On Therapeutic Patents. 13: 449-465. DOI: 10.1517/13543776.13.4.449  0.673
2002 Gratacòs E, Gavaldà N, Alberch J. Bone morphogenetic protein-6 is a neurotrophic factor for calbindin-positive striatal neurons. Journal of Neuroscience Research. 70: 638-44. PMID 12424731 DOI: 10.1002/Jnr.10438  0.457
2002 Marco S, Saura J, Pérez-Navarro E, José Martí M, Tolosa E, Alberch J. Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease. Journal of Neurobiology. 52: 343-51. PMID 12210101 DOI: 10.1002/Neu.10082  0.477
2002 Alberch J, Pérez-Navarro E, Canals JM. Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease. Brain Research Bulletin. 57: 817-22. PMID 12031278 DOI: 10.1016/S0361-9230(01)00775-4  0.695
2002 Marco S, Canudas AM, Canals JM, Gavaldà N, Pérez-Navarro E, Alberch J. Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum. Experimental Neurology. 174: 243-52. PMID 11922665 DOI: 10.1006/Exnr.2001.7859  0.671
2002 Marco S, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. Journal of Neurobiology. 50: 323-32. PMID 11891666 DOI: 10.1002/Neu.10033  0.655
2002 Reiriz J, Holm PC, Alberch J, Arenas E. BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors. Journal of Neurobiology. 50: 291-304. PMID 11891664 DOI: 10.1002/Neu.10034  0.65
2001 Gratacòs E, Checa N, Pérez-Navarro E, Alberch J. Brain-derived neurotrophic factor (BDNF) mediates bone morphogenetic protein-2 (BMP-2) effects on cultured striatal neurones. Journal of Neurochemistry. 79: 747-55. PMID 11723167 DOI: 10.1046/J.1471-4159.2001.00570.X  0.456
2001 Checa N, Canals JM, Gratacòs E, Alberch J. TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia. Experimental Neurology. 172: 282-92. PMID 11716553 DOI: 10.1006/Exnr.2001.7796  0.654
2001 Gratacòs E, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members. Journal of Neurochemistry. 78: 1287-96. PMID 11579137 DOI: 10.1046/J.1471-4159.2001.00538.X  0.668
2001 Gratacòs E, Checa N, Alberch J. Bone morphogenetic protein-2, but not bone morphogenetic protein-7, promotes dendritic growth and calbindin phenotype in cultured rat striatal neurons. Neuroscience. 104: 783-90. PMID 11440809 DOI: 10.1016/S0306-4522(01)00122-1  0.358
2001 Canals JM, Checa N, Marco S, Akerud P, Michels A, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 117-24. PMID 11150327 DOI: 10.1523/Jneurosci.21-01-00117.2001  0.756
2000 Pérez-Navarro E, Canudas AM, Akerund P, Alberch J, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. Journal of Neurochemistry. 75: 2190-9. PMID 11183872 DOI: 10.1046/J.1471-4159.2000.0752190.X  0.673
2000 Checa N, Canals JM, Alberch J. Developmental regulation of BDNF and NT-3 expression by quinolinic acid in the striatum and its main connections. Experimental Neurology. 165: 118-24. PMID 10964490 DOI: 10.1006/Exnr.2000.7451  0.676
2000 Pérez-Navarro E, Akerud P, Marco S, Canals JM, Tolosa E, Arenas E, Alberch J. Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease. Neuroscience. 98: 89-96. PMID 10858615 DOI: 10.1016/S0306-4522(00)00074-9  0.754
2000 Pavía J, Alberch J, Alvárez I, Toledano A, de Ceballos ML. Repeated intracerebroventricular administration of beta-amyloid(25-35) to rats decreases muscarinic receptors in cerebral cortex. Neuroscience Letters. 278: 69-72. PMID 10643803 DOI: 10.1016/S0304-3940(99)00900-3  0.36
1999 Pérez-Navarro E, Alberch J, Neveu I, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo. Neuroscience. 91: 1257-64. PMID 10391433 DOI: 10.1016/S0306-4522(98)00723-4  0.677
1999 Akerud P, Alberch J, Eketjäll S, Wagner J, Arenas E. Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. Journal of Neurochemistry. 73: 70-8. PMID 10386956 DOI: 10.1046/J.1471-4159.1999.0730070.X  0.778
1999 Canals JM, Checa N, Marco S, Michels A, Pérez-Navarro E, Alberch J. The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum. Brain Research. Molecular Brain Research. 69: 242-8. PMID 10366745 DOI: 10.1016/S0169-328X(99)00130-8  0.645
1999 Reiriz J, Espejo M, Ventura F, Ambrosio S, Alberch J. Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons. Journal of Neurobiology. 38: 161-70. PMID 10022564 DOI: 10.1002/(Sici)1097-4695(19990205)38:2<161::Aid-Neu1>3.0.Co;2-3  0.418
1999 Pérez-Navarro E, Arenas E, Marco S, Alberch J. Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo. The European Journal of Neuroscience. 11: 241-9. PMID 9987028 DOI: 10.1046/J.1460-9568.1999.00433.X  0.679
1998 Canals JM, Marco S, Checa N, Michels A, Pérez-Navarro E, Arenas E, Alberch J. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiology of Disease. 5: 357-64. PMID 10069578 DOI: 10.1006/Nbdi.1998.0211  0.746
1998 Graus F, Gultekin SH, Ferrer I, Reiriz J, Alberch J, Dalmau J. Localization of the neuronal antigen recognized by anti-Tr antibodies from patients with paraneoplastic cerebellar degeneration and Hodgkin's disease in the rat nervous system. Acta Neuropathologica. 96: 1-7. PMID 9678507 DOI: 10.1007/S004010050853  0.373
1998 Ferrer I, Ballabriga J, Martí E, Pérez E, Alberch J, Arenas E. BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia. Brain Pathology (Zurich, Switzerland). 8: 253-61. PMID 9546284 DOI: 10.1111/J.1750-3639.1998.Tb00151.X  0.628
1997 Canals JM, Pérez-Navarro E, Ruiz-Avila L, Alberch J, Calvo N, Martín-Zanca D, Marsal J. A brain-derived neurotrophic factor (BDNF) related system is involved in the maintenance of the polyinnervate Torpedo electric organ. Neurochemistry International. 31: 33-8. PMID 9185162 DOI: 10.1016/S0197-0186(96)00133-7  0.634
1996 Calvo N, Reiriz J, Pérez-Navarro E, Alberch J. Tachykinins protect cholinergic neurons from quinolinic acid excitotoxicity in striatal cultures. Brain Research. 740: 323-8. PMID 8973830 DOI: 10.1016/S0006-8993(96)00879-7  0.425
1996 Pérez-Navarro E, Arenas E, Reiriz J, Calvo N, Alberch J. Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage. Neuroscience. 75: 345-52. PMID 8931001 DOI: 10.1016/0306-4522(96)00336-3  0.675
1996 van Praag H, Alberch J, Perez-Navarro E, Wu H, Qu PM, Black IB, Dreyfus CF. Unilateral neonatal hippocampal lesion alters septal innervation and trophism of the entorhinal cortex. Experimental Neurology. 141: 130-40. PMID 8797675 DOI: 10.1006/Exnr.1996.0146  0.335
1995 Pérez-Navarro E, Alberch J. Protective role of nerve growth factor against excitatory amino acid injury during neostriatal cholinergic neurons postnatal development. Experimental Neurology. 135: 146-52. PMID 7589325 DOI: 10.1006/Exnr.1995.1073  0.381
1995 Mount HT, Dean DO, Alberch J, Dreyfus CF, Black IB. Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9092-6. PMID 7568079 DOI: 10.1073/Pnas.92.20.9092  0.462
1994 Pérez-Navarro E, Alberch J, Arenas E, Calvo N, Marsal J. Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum. The European Journal of Neuroscience. 6: 706-11. PMID 8075815 DOI: 10.1111/J.1460-9568.1994.Tb00982.X  0.585
1993 Pérez-Navarro E, Alberch J, Arenas E, Marsal J. Nerve growth factor and its receptor are differentially modified by chronic naltrexone treatment during rat brain development. Neuroscience Letters. 149: 47-50. PMID 8469378 DOI: 10.1016/0304-3940(93)90344-K  0.573
1993 Pérez-Navarro E, Alberch J, Marsal J. Postnatal development of functional dopamine, opioid and tachykinin receptors that regulate acetylcholine release from rat neostriatal slices. Effect of 6-hydroxydopamine lesion. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 11: 701-8. PMID 8135128 DOI: 10.1016/0736-5748(93)90059-M  0.339
1993 Arenas E, Pérez-Navarro E, Alberch J, Marsal J. Selective resistance of tachykinin-responsive cholinergic neurons in the quinolinic acid lesioned neostriatum. Brain Research. 603: 317-20. PMID 7681719 DOI: 10.1016/0006-8993(93)91254-P  0.592
1993 Alberch J, Arenas E, Pérez-Navarro E, Marsal J. Control of tachykinin-evoked acetylcholine release from rat striatal slices by dopaminergic neurons. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 445-9. PMID 7509458 DOI: 10.1007/Bf00173201  0.568
1991 Arenas E, Alberch J, Pérez-Navarro E, Solsona C, Marsal J. Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release. Brain Research. 556: 349-52. PMID 1933369 DOI: 10.1016/0006-8993(91)90329-T  0.54
1991 Arenas E, Alberch J, Marsal J. Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices. Neuroscience. 42: 707-14. PMID 1683474 DOI: 10.1016/0306-4522(91)90039-Q  0.539
1991 Alberch J, Brito B, Notario V, Castro R. Prenatal haloperidol treatment decreases nerve growth factor receptor and mRNA in neonate rat forebrain. Neuroscience Letters. 131: 228-32. PMID 1662344 DOI: 10.1016/0304-3940(91)90620-9  0.308
1991 Alberch J, Pérez-Navarro E, Arenas E, Marsal J. Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats. Journal of Neurochemistry. 57: 1483-7. PMID 1655975 DOI: 10.1111/J.1471-4159.1991.Tb06342.X  0.56
1991 Arenas E, Alberch J, Perez-Navarro E, Solsona C, Marsal J. Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2332-8. PMID 1651375 DOI: 10.1523/Jneurosci.11-08-02332.1991  0.591
1990 Alberch J, Arenas E, Sánchez Arroyos R, Marsal J. Excitatory amino acids release endogenous acetylcholine from rat striatal slices: Regulation by gamma-aminobutyric acid. Neurochemistry International. 17: 107-16. PMID 20504609 DOI: 10.1016/0197-0186(90)90074-4  0.54
1990 Arenas E, Marsal J, Alberch J. GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices. Neuroscience Letters. 120: 201-4. PMID 1981386 DOI: 10.1016/0304-3940(90)90038-B  0.542
1990 Arenas E, Alberch J, Sanchez Arroyos R, Marsal J. Effect of opioids on acetylcholine release evoked by K+ or glutamic acid from rat neostriatal slices. Brain Research. 523: 51-6. PMID 1976420 DOI: 10.1016/0006-8993(90)91633-R  0.538
Show low-probability matches.