Jordi Alberch - Publications

Affiliations: 
Universitat de Barcelona, Barcelona, Cataluña, Spain 

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kim A, García-García E, Straccia M, Comella-Bolla A, Miguez A, Masana M, Alberch J, Canals JM, Rodríguez MJ. Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease. Frontiers in Cellular Neuroscience. 14: 163. PMID 32625064 DOI: 10.3389/Fncel.2020.00163  0.571
2020 Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, et al. Modulation of dopamine D receptors via histamine H receptors is a novel therapeutic target for Huntington's disease. Elife. 9. PMID 32513388 DOI: 10.7554/Elife.51093  0.365
2020 Fernández-García S, Sancho-Balsells A, Longueville S, Hervé D, Gruart A, Delgado-García JM, Alberch J, Giralt A. Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy. Cell Death & Disease. 11: 411. PMID 32483154 DOI: 10.1038/S41419-020-2615-9  0.382
2020 Sancho-Balsells A, Brito V, Fernández B, Pardo M, Straccia M, Ginés S, Alberch J, Hernández I, Arranz B, Canals JM, Giralt A. Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1. Frontiers in Cellular Neuroscience. 14: 93. PMID 32477064 DOI: 10.3389/Fncel.2020.00093  0.571
2020 Fernández-García S, Orlandi JG, García-Díaz Barriga GA, Rodríguez MJ, Masana M, Soriano J, Alberch J. Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington's disease. Bmc Biology. 18: 58. PMID 32466798 DOI: 10.1186/S12915-020-00794-4  0.308
2020 Comella-Bolla A, Orlandi JG, Miguez A, Straccia M, García-Bravo M, Bombau G, Galofré M, Sanders P, Carrere J, Segovia JC, Blasi J, Allen ND, Alberch J, Soriano J, Canals JM. Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation. Molecular Neurobiology. PMID 32356172 DOI: 10.1007/S12035-020-01907-4  0.648
2019 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martín-Ibáñez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, García-Torralba A, Pascual M, Pumarola M, Alberch J, Ginés S, et al. Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Experimental Neurology. 113095. PMID 31712124 DOI: 10.1016/J.Expneurol.2019.113095  0.603
2019 Creus-Muncunill J, Badillos-Rodríguez R, Garcia-Forn M, Masana M, Garcia-Díaz Barriga G, Guisado-Corcoll A, Alberch J, Malagelada C, Delgado-García JM, Gruart A, Pérez-Navarro E. Increased translation as a novel pathogenic mechanism in Huntington's disease. Brain : a Journal of Neurology. PMID 31365052 DOI: 10.1093/Brain/Awz230  0.351
2019 de Pins B, Cifuentes-Díaz C, Thamila Farah A, López-Molina L, Montalban E, Sancho-Balsells A, López A, Ginés S, Delgado-García JM, Alberch J, Gruart A, Girault JA, Giralt A. Conditional BDNF delivery from astrocytes rescues memory deficits, spine density and synaptic properties in the 5xFAD mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30700530 DOI: 10.1523/Jneurosci.2121-18.2019  0.353
2019 Montalban E, Al-Massadi O, Sancho-Balsells A, Brito V, de Pins B, Alberch J, Ginés S, Girault JA, Giralt A. Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes. Translational Psychiatry. 9: 3. PMID 30664624 DOI: 10.1038/S41398-018-0352-Y  0.3
2019 Rodríguez-Urgellés E, Fernández-García S, Orlandi J, Barriga GG, Rodríguez M, Soriano J, Alberch J, Masana M. Brain-derived neurotrophic factor modulates neuronal network structure and dynamics in striatal cultures: Implications for Huntington's disease European Neuropsychopharmacology. 29: S160-S161. DOI: 10.1016/J.Euroneuro.2018.11.280  0.359
2018 Saavedra A, Ballesteros JJ, Tyebji S, Martínez-Torres S, Blázquez G, López-Hidalgo R, Azkona G, Alberch J, Martín ED, Pérez-Navarro E. Proteolytic Degradation of Hippocampal STEP in LTP and Learning. Molecular Neurobiology. PMID 29948948 DOI: 10.1007/S12035-018-1170-1  0.311
2018 Suelves N, Miguez A, López-Benito S, Barriga GG, Giralt A, Alvarez-Periel E, Arévalo JC, Alberch J, Ginés S, Brito V. Early Downregulation of p75 by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington's Disease Mice. Molecular Neurobiology. PMID 29804232 DOI: 10.1007/S12035-018-1126-5  0.37
2018 Cabezas-Llobet N, Vidal-Sancho L, Masana M, Fournier A, Alberch J, Vaudry D, Xifró X. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Enhances Hippocampal Synaptic Plasticity and Improves Memory Performance in Huntington's Disease. Molecular Neurobiology. 55: 8263-8277. PMID 29526016 DOI: 10.1007/S12035-018-0972-5  0.322
2018 Creus-Muncunill J, Rué L, Alcalá-Vida R, Badillos-Rodríguez R, Romaní-Aumedes J, Marco S, Alberch J, Perez-Otaño I, Malagelada C, Pérez-Navarro E. Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration. Molecular Neurobiology. PMID 29460266 DOI: 10.1007/S12035-018-0956-5  0.414
2017 Giralt A, Gómez-Climent MÁ, Alcalá R, Bretin S, Bertrand D, María Delgado-García J, Pérez-Navarro E, Alberch J, Gruart A. The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice. Neuropharmacology. PMID 28603025 DOI: 10.1016/J.Neuropharm.2017.06.009  0.301
2017 Giralt A, Brito V, Chevy Q, Simonnet C, Otsu Y, Cifuentes-Díaz C, de Pins B, Coura R, Alberch J, Ginés S, Poncer JC, Girault JA. Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model. Nature Communications. 8: 15592. PMID 28555636 DOI: 10.1038/Ncomms15592  0.34
2017 García-Díaz Barriga G, Giralt A, Anglada-Huguet M, Gaja-Capdevila N, Orlandi JG, Soriano J, Canals JM, Alberch J. 7,8 Dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway. Human Molecular Genetics. PMID 28541476 DOI: 10.1093/Hmg/Ddx198  0.374
2017 Martín-Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Barriga GG, Edel MJ, Vicario-Abejón C, Alberch J, Girault JA, Chan S, Kastner P, et al. Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development (Cambridge, England). PMID 28289129 DOI: 10.1242/Dev.138248  0.649
2016 Canal M, Martín-Flores N, Pérez-Sisqués L, Romaní-Aumedes J, Altas B, Man HY, Kawabe H, Alberch J, Malagelada C. Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease. Oncotarget. PMID 27494837 DOI: 10.18632/Oncotarget.11020  0.369
2015 Fernández-Santiago R, Carballo-Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez-Danés A, Vilarrasa-Blasi R, Sánchez-Pla A, Mosquera JL, Soriano J, López-Barneo J, Canals JM, Alberch J, Raya Á, Vila M, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. Embo Molecular Medicine. PMID 26516212 DOI: 10.15252/Emmm.201505439  0.584
2015 Puigdellívol M, Cherubini M, Brito V, Giralt A, Suelves N, Ballesteros J, Zamora-Moratalla A, Martín ED, Eipper BA, Alberch J, Ginés S. A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease. Human Molecular Genetics. PMID 26464483 DOI: 10.1093/Hmg/Ddv426  0.32
2015 Straccia M, Garcia-Diaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal PB, Vinh NN, Yung S, Kelly CM, Svendsen CN, Kemp PJ, Arjomand J, Schoenfeld RC, Alberch J, Allen ND, et al. Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons. Molecular Therapy. Methods & Clinical Development. 2: 15030. PMID 26417608 DOI: 10.1038/Mtm.2015.30  0.613
2015 Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular Neurobiology. PMID 26223799 DOI: 10.1007/S12035-015-9335-7  0.382
2015 Fernández-Nogales M, Hernández F, Miguez A, Alberch J, Ginés S, Pérez-Navarro E, Lucas JJ. Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease. Human Molecular Genetics. 24: 5040-52. PMID 26082469 DOI: 10.1093/Hmg/Ddv224  0.337
2015 Miguez A, García-Díaz Barriga G, Brito V, Straccia M, Giralt A, Ginés S, Canals JM, Alberch J. Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation. Human Molecular Genetics. 24: 4958-70. PMID 26063761 DOI: 10.1093/Hmg/Ddv218  0.571
2015 Martín-Flores N, Romaní-Aumedes J, Rué L, Canal M, Sanders P, Straccia M, Allen ND, Alberch J, Canals JM, Pérez-Navarro E, Malagelada C. RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death. Molecular Neurobiology. PMID 25876513 DOI: 10.1007/S12035-015-9166-6  0.654
2015 Tyebji S, Saavedra A, Canas PM, Pliassova A, Delgado-García JM, Alberch J, Cunha RA, Gruart A, Pérez-Navarro E. Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease. Neurobiology of Disease. 74: 41-57. PMID 25449908 DOI: 10.1016/J.Nbd.2014.11.004  0.333
2014 Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, et al. Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. Cell Death & Disease. 5: e1364. PMID 25101677 DOI: 10.1038/Cddis.2014.333  0.398
2014 Moreno B, Lopez I, Fernández-Díez B, Gottlieb M, Matute C, Sánchez-Gómez MV, Domercq M, Giralt A, Alberch J, Collon KW, Zhang H, Parent JM, Teixido M, Giralt E, Ceña V, et al. Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine. Plos One. 9: e90671. PMID 24599318 DOI: 10.1371/Journal.Pone.0090671  0.385
2014 Canadell M, Moreno-Delgado D, Rodriguez-Ruiz M, Moreno E, Botta J, Gasperini P, Cordomi A, Howell L, Navarro G, Casado V, Ferre S, Guzman M, Pardo L, Alberch J, Canela E, et al. M17 Targeting Dopamine D1-histamine H3 Receptor Heteromers As A Therapeutical Strategy To Prevent Cognitive Deficits And Neurodegeneration In Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A100-A100. DOI: 10.1136/Jnnp-2014-309032.289  0.349
2014 Saavedra A, Tyebji S, Canas P, Pliassova A, Delgado-Garcia J, Alberch J, Cunha R, Gruart A, Perez-Navarro E. M16 D1R and A2AR Blockade Normalises PKA Activity and Improves Hippocampal-dependent Cognitive Dysfunction but not Motor Deficits in Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A100. DOI: 10.1136/Jnnp-2014-309032.288  0.317
2014 Miguez A, Garcia G, Brito V, Straccia M, Giralt A, Gines S, Canals J, Alberch J. M15 Fingolimod (FTY720) Enhances Hippocampal Synaptic Plasticity and Memory in Huntington's Disease by Preventing P75NTR/TRKB Imbalance Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.287  0.571
2014 Diaz Barriga A, Giralt A, Anglada-Huguet M, Canals J, Alberch J. M14 7,8 Dihydroxyflavone Ameliorates Cognitive And Motor Deficits In A Huntingon's Disease Mouse Model Through A Different Activation Profile From Bdnf Journal of Neurology, Neurosurgery & Psychiatry. 85: A99-A99. DOI: 10.1136/Jnnp-2014-309032.286  0.571
2013 Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, ... Alberch J, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8. PMID 23852340 DOI: 10.1038/Nm.3246  0.373
2013 Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, et al. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Human Molecular Genetics. 22: 3869-82. PMID 23720495 DOI: 10.1093/Hmg/Ddt242  0.609
2012 Canela L, Selga E, García-Martínez JM, Amaral OB, Fernández-Dueñas V, Alberch J, Canela EI, Franco R, Noé V, Lluís C, Ciudad CJ, Ciruela F. Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene. 508: 199-205. PMID 22892378 DOI: 10.1016/J.Gene.2012.07.074  0.348
2012 Carretón O, Giralt A, Torres-Peraza JF, Brito V, Lucas JJ, Ginés S, Canals JM, Alberch J. Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels. Experimental Neurology. 237: 335-45. PMID 22776425 DOI: 10.1016/J.Expneurol.2012.06.033  0.571
2012 Ruiz C, Casarejos MJ, Rubio I, Gines S, Puigdellivol M, Alberch J, Mena MA, de Yebenes JG. The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins. Brain Research. 1459: 100-12. PMID 22560595 DOI: 10.1016/J.Brainres.2012.04.021  0.4
2012 Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, Jiménez-Delgado S, Caig C, Mora S, Di Guglielmo C, Ezquerra M, Patel B, Giralt A, Canals JM, Memo M, Alberch J, López-Barneo J, Vila M, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. Embo Molecular Medicine. 4: 380-95. PMID 22407749 DOI: 10.1002/Emmm.201200215  0.588
2012 Martín-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martínez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM. Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells and Development. 21: 2239-51. PMID 22142223 DOI: 10.1089/Scd.2011.0607  0.638
2011 Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8150-62. PMID 21632937 DOI: 10.1523/Jneurosci.3446-10.2011  0.371
2011 Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, ... ... Alberch J, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278  0.338
2010 Urbán N, Martín-Ibáñez R, Herranz C, Esgleas M, Crespo E, Pardo M, Crespo-Enríquez I, Méndez-Gómez HR, Waclaw R, Chatzi C, Alvarez S, Alvarez R, Duester G, Campbell K, de Lera AR, ... ... Alberch J, et al. Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling. Neural Development. 5: 21. PMID 20735826 DOI: 10.1186/1749-8104-5-21  0.609
2010 del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J. Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease. Journal of Neurochemistry. 115: 153-67. PMID 20663016 DOI: 10.1111/J.1471-4159.2010.06912.X  0.597
2010 Giralt A, Friedman HC, Caneda-Ferrón B, Urbán N, Moreno E, Rubio N, Blanco J, Peterson A, Canals JM, Alberch J. BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease. Gene Therapy. 17: 1294-308. PMID 20463759 DOI: 10.1038/Gt.2010.71  0.571
2010 Ginés S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. The Journal of Biological Chemistry. 285: 21537-48. PMID 20442398 DOI: 10.1074/Jbc.M109.084202  0.35
2010 Twohig JP, Roberts MI, Gavalda N, Rees-Taylor EL, Giralt A, Adams D, Brooks SP, Bull MJ, Calder CJ, Cuff S, Yong AA, Alberch J, Davies A, Dunnett SB, Tolkovsky AM, et al. Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3782-92. PMID 20220013 DOI: 10.1523/Jneurosci.1928-09.2010  0.387
2010 Martín-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, Marín O, Georgopoulos K, Mengod G, Fariñas I, ... ... Alberch J, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. The Journal of Comparative Neurology. 518: 329-51. PMID 19950118 DOI: 10.1002/Cne.22215  0.652
2010 Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum. Cell Death and Differentiation. 17: 324-35. PMID 19745829 DOI: 10.1038/Cdd.2009.127  0.571
2010 Alberch J, Pérez-Navarro E, Canals JM. Animal Models of Huntington's Disease Encyclopedia of Neuroscience. 429-436. DOI: 10.1016/B978-008045046-9.00502-7  0.527
2009 Díaz-Hernández M, Díez-Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT, Lucas JJ. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1893-906. PMID 19171786 DOI: 10.1096/Fj.08-122275  0.571
2009 del Toro D, Alberch J, Lázaro-Diéguez F, Martín-Ibáñez R, Xifró X, Egea G, Canals JM. Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus. Molecular Biology of the Cell. 20: 1478-92. PMID 19144827 DOI: 10.1091/Mbc.E08-07-0726  0.571
2009 Giralt A, Rodrigo T, Martín ED, Gonzalez JR, Milà M, Ceña V, Dierssen M, Canals JM, Alberch J. Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression. Neuroscience. 158: 1234-50. PMID 19121372 DOI: 10.1016/J.Neuroscience.2008.11.024  0.609
2008 Paoletti P, Vila I, Rifé M, Lizcano JM, Alberch J, Ginés S. Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10090-101. PMID 18829967 DOI: 10.1523/Jneurosci.3237-08.2008  0.362
2008 Torres-Peraza JF, Giralt A, García-Martínez JM, Pedrosa E, Canals JM, Alberch J. Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling. Neurobiology of Disease. 29: 409-21. PMID 18063376 DOI: 10.1016/J.Nbd.2007.10.003  0.571
2007 García-Martínez JM, Pérez-Navarro E, Xifró X, Canals JM, Díaz-Hernández M, Trioulier Y, Brouillet E, Lucas JJ, Alberch J. BH3-only proteins Bid and Bim(EL) are differentially involved in neuronal dysfunction in mouse models of Huntington's disease. Journal of Neuroscience Research. 85: 2756-69. PMID 17387706 DOI: 10.1002/Jnr.21258  0.571
2007 Martín-Ibáñez R, Urbán N, Sergent-Tanguy S, Pineda JR, Garrido-Clua N, Alberch J, Canals JM. Interplay of leukemia inhibitory factor and retinoic acid on neural differentiation of mouse embryonic stem cells. Journal of Neuroscience Research. 85: 2686-701. PMID 17348039 DOI: 10.1002/Jnr.21228  0.624
2007 Torres-Peraza J, Pezzi S, Canals JM, Gavaldà N, García-Martínez JM, Pérez-Navarro E, Alberch J. Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. Neuroscience. 144: 462-71. PMID 17081696 DOI: 10.1016/J.Neuroscience.2006.09.038  0.571
2007 Pineda JR, Rubio N, Akerud P, Urbán N, Badimon L, Arenas E, Alberch J, Blanco J, Canals JM. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells. Gene Therapy. 14: 118-28. PMID 16943855 DOI: 10.1038/Sj.Gt.3302847  0.703
2006 del Toro D, Canals JM, Ginés S, Kojima M, Egea G, Alberch J. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12748-57. PMID 17151278 DOI: 10.1523/Jneurosci.3873-06.2006  0.571
2006 Dierssen M, Gratacòs M, Sahún I, Martín M, Gallego X, Amador-Arjona A, Martínez de Lagrán M, Murtra P, Martí E, Pujana MA, Ferrer I, Dalfó E, Martínez-Cué C, Flórez J, Torres-Peraza JF, ... Alberch J, et al. Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction. Neurobiology of Disease. 24: 403-18. PMID 16963267 DOI: 10.1016/J.Nbd.2006.07.015  0.363
2006 Pérez-Navarro E, Canals JM, Ginés S, Alberch J. Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington's disease. Histology and Histopathology. 21: 1217-32. PMID 16874665  0.527
2006 Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/Jci27607  0.63
2006 Ginés S, Bosch M, Marco S, Gavaldà N, Díaz-Hernández M, Lucas JJ, Canals JM, Alberch J. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. The European Journal of Neuroscience. 23: 649-58. PMID 16487146 DOI: 10.1111/J.1460-9568.2006.04590.X  0.709
2005 Alberch J, López M, Badenas C, Carrasco JL, Milà M, Muñoz E, Canals JM. Association between BDNF Val66Met polymorphism and age at onset in Huntington disease. Neurology. 65: 964-5. PMID 16186551 DOI: 10.1212/01.Wnl.0000175977.57661.B1  0.571
2005 Orive G, De Castro M, Ponce S, Hernández RM, Gascón AR, Bosch M, Alberch J, Pedraz JL. Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 283-9. PMID 15935736 DOI: 10.1016/J.Ymthe.2005.04.002  0.503
2005 Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J. Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease. Journal of Neurochemistry. 93: 1057-68. PMID 15934928 DOI: 10.1111/J.1471-4159.2005.03047.X  0.72
2005 Canudas AM, Pezzi S, Canals JM, Pallàs M, Alberch J. Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury. Brain Research. Molecular Brain Research. 134: 147-54. PMID 15790538 DOI: 10.1016/J.Molbrainres.2004.11.012  0.571
2004 Bosch M, Pineda JR, Suñol C, Petriz J, Cattaneo E, Alberch J, Canals JM. Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease. Experimental Neurology. 190: 42-58. PMID 15473979 DOI: 10.1016/J.Expneurol.2004.06.027  0.714
2004 Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7727-39. PMID 15342740 DOI: 10.1523/Jneurosci.1197-04.2004  0.73
2004 Sieber BA, Kuzmin A, Canals JM, Danielsson A, Paratcha G, Arenas E, Alberch J, Ogren SO, Ibáñez CF. Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Molecular and Cellular Neurosciences. 26: 418-28. PMID 15234346 DOI: 10.1016/J.Mcn.2004.03.009  0.701
2004 Alberch J, Pérez-Navarro E, Canals JM. Neurotrophic factors in Huntington's disease. Progress in Brain Research. 146: 195-229. PMID 14699966 DOI: 10.1016/S0079-6123(03)46014-7  0.571
2003 Alberch J, Canals JM, Pérez-Navarro E. Therapeutic strategies in Huntington's disease Expert Opinion On Therapeutic Patents. 13: 449-465. DOI: 10.1517/13543776.13.4.449  0.571
2002 Alberch J, Pérez-Navarro E, Canals JM. Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease. Brain Research Bulletin. 57: 817-22. PMID 12031278 DOI: 10.1016/S0361-9230(01)00775-4  0.571
2002 Marco S, Canudas AM, Canals JM, Gavaldà N, Pérez-Navarro E, Alberch J. Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum. Experimental Neurology. 174: 243-52. PMID 11922665 DOI: 10.1006/Exnr.2001.7859  0.571
2002 Marco S, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. Journal of Neurobiology. 50: 323-32. PMID 11891666 DOI: 10.1002/Neu.10033  0.614
2002 Reiriz J, Holm PC, Alberch J, Arenas E. BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors. Journal of Neurobiology. 50: 291-304. PMID 11891664 DOI: 10.1002/Neu.10034  0.609
2001 Checa N, Canals JM, Gratacòs E, Alberch J. TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia. Experimental Neurology. 172: 282-92. PMID 11716553 DOI: 10.1006/Exnr.2001.7796  0.571
2001 Gratacòs E, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members. Journal of Neurochemistry. 78: 1287-96. PMID 11579137 DOI: 10.1046/J.1471-4159.2001.00538.X  0.622
2001 Canals JM, Checa N, Marco S, Akerud P, Michels A, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 117-24. PMID 11150327 DOI: 10.1523/Jneurosci.21-01-00117.2001  0.722
2000 Pérez-Navarro E, Canudas AM, Akerund P, Alberch J, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. Journal of Neurochemistry. 75: 2190-9. PMID 11183872 DOI: 10.1046/J.1471-4159.2000.0752190.X  0.623
2000 Checa N, Canals JM, Alberch J. Developmental regulation of BDNF and NT-3 expression by quinolinic acid in the striatum and its main connections. Experimental Neurology. 165: 118-24. PMID 10964490 DOI: 10.1006/Exnr.2000.7451  0.571
2000 Pérez-Navarro E, Akerud P, Marco S, Canals JM, Tolosa E, Arenas E, Alberch J. Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease. Neuroscience. 98: 89-96. PMID 10858615 DOI: 10.1016/S0306-4522(00)00074-9  0.73
1999 Pérez-Navarro E, Alberch J, Neveu I, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo. Neuroscience. 91: 1257-64. PMID 10391433 DOI: 10.1016/S0306-4522(98)00723-4  0.626
1999 Akerud P, Alberch J, Eketjäll S, Wagner J, Arenas E. Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. Journal of Neurochemistry. 73: 70-8. PMID 10386956 DOI: 10.1046/J.1471-4159.1999.0730070.X  0.747
1999 Canals JM, Checa N, Marco S, Michels A, Pérez-Navarro E, Alberch J. The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum. Brain Research. Molecular Brain Research. 69: 242-8. PMID 10366745 DOI: 10.1016/S0169-328X(99)00130-8  0.571
1999 Pérez-Navarro E, Arenas E, Marco S, Alberch J. Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo. The European Journal of Neuroscience. 11: 241-9. PMID 9987028 DOI: 10.1046/J.1460-9568.1999.00433.X  0.628
1998 Canals JM, Marco S, Checa N, Michels A, Pérez-Navarro E, Arenas E, Alberch J. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiology of Disease. 5: 357-64. PMID 10069578 DOI: 10.1006/Nbdi.1998.0211  0.715
1998 Ferrer I, Ballabriga J, Martí E, Pérez E, Alberch J, Arenas E. BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia. Brain Pathology (Zurich, Switzerland). 8: 253-61. PMID 9546284 DOI: 10.1111/J.1750-3639.1998.Tb00151.X  0.59
1997 Canals JM, Pérez-Navarro E, Ruiz-Avila L, Alberch J, Calvo N, Martín-Zanca D, Marsal J. A brain-derived neurotrophic factor (BDNF) related system is involved in the maintenance of the polyinnervate Torpedo electric organ. Neurochemistry International. 31: 33-8. PMID 9185162 DOI: 10.1016/S0197-0186(96)00133-7  0.571
1996 Pérez-Navarro E, Arenas E, Reiriz J, Calvo N, Alberch J. Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage. Neuroscience. 75: 345-52. PMID 8931001 DOI: 10.1016/0306-4522(96)00336-3  0.628
1996 van Praag H, Alberch J, Perez-Navarro E, Wu H, Qu PM, Black IB, Dreyfus CF. Unilateral neonatal hippocampal lesion alters septal innervation and trophism of the entorhinal cortex. Experimental Neurology. 141: 130-40. PMID 8797675 DOI: 10.1006/Exnr.1996.0146  0.303
1995 Mount HT, Dean DO, Alberch J, Dreyfus CF, Black IB. Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9092-6. PMID 7568079 DOI: 10.1073/Pnas.92.20.9092  0.404
1994 Pérez-Navarro E, Alberch J, Arenas E, Calvo N, Marsal J. Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum. The European Journal of Neuroscience. 6: 706-11. PMID 8075815 DOI: 10.1111/J.1460-9568.1994.Tb00982.X  0.564
1993 Pérez-Navarro E, Alberch J, Arenas E, Marsal J. Nerve growth factor and its receptor are differentially modified by chronic naltrexone treatment during rat brain development. Neuroscience Letters. 149: 47-50. PMID 8469378 DOI: 10.1016/0304-3940(93)90344-K  0.554
1993 Arenas E, Pérez-Navarro E, Alberch J, Marsal J. Selective resistance of tachykinin-responsive cholinergic neurons in the quinolinic acid lesioned neostriatum. Brain Research. 603: 317-20. PMID 7681719 DOI: 10.1016/0006-8993(93)91254-P  0.576
1993 Alberch J, Arenas E, Pérez-Navarro E, Marsal J. Control of tachykinin-evoked acetylcholine release from rat striatal slices by dopaminergic neurons. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 445-9. PMID 7509458 DOI: 10.1007/Bf00173201  0.556
1991 Arenas E, Alberch J, Pérez-Navarro E, Solsona C, Marsal J. Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release. Brain Research. 556: 349-52. PMID 1933369 DOI: 10.1016/0006-8993(91)90329-T  0.543
1991 Arenas E, Alberch J, Marsal J. Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices. Neuroscience. 42: 707-14. PMID 1683474 DOI: 10.1016/0306-4522(91)90039-Q  0.54
1991 Alberch J, Pérez-Navarro E, Arenas E, Marsal J. Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats. Journal of Neurochemistry. 57: 1483-7. PMID 1655975 DOI: 10.1111/J.1471-4159.1991.Tb06342.X  0.543
1991 Arenas E, Alberch J, Perez-Navarro E, Solsona C, Marsal J. Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2332-8. PMID 1651375 DOI: 10.1523/Jneurosci.11-08-02332.1991  0.573
1990 Alberch J, Arenas E, Sánchez Arroyos R, Marsal J. Excitatory amino acids release endogenous acetylcholine from rat striatal slices: Regulation by gamma-aminobutyric acid. Neurochemistry International. 17: 107-16. PMID 20504609 DOI: 10.1016/0197-0186(90)90074-4  0.538
1990 Arenas E, Marsal J, Alberch J. GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices. Neuroscience Letters. 120: 201-4. PMID 1981386 DOI: 10.1016/0304-3940(90)90038-B  0.543
1990 Arenas E, Alberch J, Sanchez Arroyos R, Marsal J. Effect of opioids on acetylcholine release evoked by K+ or glutamic acid from rat neostriatal slices. Brain Research. 523: 51-6. PMID 1976420 DOI: 10.1016/0006-8993(90)91633-R  0.54
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