Nicholas M. Boulis - Publications

Affiliations: 
Neurosurgery Emory University, Atlanta, GA 
Area:
Gene Therapy

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Texakalidis P, Tora MS, Federici T, Javidfar JJ, Boulis NM. Thoracoscopic delivery of therapeutics in the swine sympathetic chain: Implications for future neuromodulation. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 32336639 DOI: 10.1016/J.Jocn.2020.04.099  0.319
2020 Tora MS, Texakalidis P, Neill S, Wetzel J, Rindler RS, Hardcastle N, Nagarajan PP, Krasnopeyev A, Roach C, James R, Bruce JN, Canoll P, Federici T, Oshinski JN, Boulis NM. Lentiviral Vector Induced Modeling of High-Grade Spinal Cord Glioma in Minipigs. Scientific Reports. 10: 5291. PMID 32210315 DOI: 10.1038/S41598-020-62167-9  0.343
2019 O'Connor DM, Lutomski C, Jarrold MF, Boulis NM, Donsante A. Lot-to-lot Variation in Adeno-associated Virus Serotype 9 (AAV9) Preparations. Human Gene Therapy Methods. PMID 31752530 DOI: 10.1089/Hgtb.2019.105  0.309
2019 Texakalidis P, Tora MS, Nagarajan P, Keifer OP, Boulis NM. High cervical spinal cord stimulation for occipital neuralgia: a case series and literature review. Journal of Pain Research. 12: 2547-2553. PMID 31686897 DOI: 10.2147/Jpr.S214314  0.361
2019 Gross SK, Shim BS, Bartus RT, Deaver D, Mceachin Z, Betourne A, Boulis NM, Maragakis NJ. Focal and dose-dependent neuroprotection in ALS mice following AAV2-neurturin delivery. Experimental Neurology. 113091. PMID 31678350 DOI: 10.1016/J.Expneurol.2019.113091  0.394
2019 Texakalidis P, Tora MS, Canute S, Hardcastle N, Poth K, Donsante A, Federici T, Javidfar J, Boulis NM. Minimally Invasive Injection to the Phrenic Nerve in a Porcine Hemidiaphragmatic Paralysis Model: A Pilot Study. Neurosurgery. PMID 31625573 DOI: 10.1093/Neuros/Nyz473  0.39
2019 Anthony CL, Tora MS, Bentley JN, Texakalidis P, Boulis NM. Dorsal Root Ganglion Stimulation for Thoracic Neuralgia: A Report of Six Cases. Cureus. 11: e4615. PMID 31312542 DOI: 10.7759/Cureus.4615  0.314
2019 Mazzini L, Gelati M, Profico DC, Sorarù G, Ferrari D, Copetti M, Muzi G, Ricciolini C, Carletti S, Giorgi C, Spera C, Frondizi D, Masiero S, Stecco A, Cisari C, ... ... Boulis NM, et al. Results from Phase I Clinical Trial with Intraspinal Injection of Neural Stem Cells in Amyotrophic Lateral Sclerosis: A Long-Term Outcome. Stem Cells Translational Medicine. PMID 31104357 DOI: 10.1002/Sctm.18-0154  0.367
2019 Boulis NM. Intrathecal Riluzole for the Treatment of Patients With Amyotrophic Lateral Sclerosis Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_818  0.309
2019 Tora MS, Texakalidis P, Boulis NM. The Neurosurgeons' Armamentarium for the Management of Refractory Post-Herpetic Neuralgia Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_196  0.345
2018 Mlaver E, Keifer O, Tora MS, Campbell M, Boulis NM. Case Report: Phantom Sensation - An Underreported Sensory Outcome Following Intercostal-to-Musculocutaneous Nerve Transfer. World Neurosurgery. PMID 30415052 DOI: 10.1016/J.Wneu.2018.10.216  0.302
2018 Donsante A, Boulis NM. Progress in gene and cell therapies for the neuronal ceroid lipofuscinoses. Expert Opinion On Biological Therapy. PMID 29936867 DOI: 10.1080/14712598.2018.1492544  0.361
2018 Goutman SA, Brown MB, Glass JD, Boulis NM, Johe K, Hazel T, Cudkowicz M, Atassi N, Borges L, Patil PG, Sakowski SA, Feldman EL. Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS. Annals of Clinical and Translational Neurology. 5: 730-740. PMID 29928656 DOI: 10.1002/Acn3.567  0.316
2017 Hardcastle N, Boulis NM, Federici T. AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials. Expert Opinion On Biological Therapy. 1-15. PMID 29249183 DOI: 10.1080/14712598.2018.1416089  0.408
2017 Squires A, Oshinski JN, Boulis NM, Tse ZTH. SpinoBot: An MRI-Guided Needle Positioning System for Spinal Cellular Therapeutics. Annals of Biomedical Engineering. PMID 29150766 DOI: 10.1007/S10439-017-1960-Z  0.376
2017 Lamanna JJ, Gutierrez J, Espinosa JR, Wagner J, Urquia LN, Moreton C, Victor Hurtig C, Tora M, Kirk AD, Federici T, Boulis NM. Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 29089163 DOI: 10.1016/J.Jocn.2017.10.033  0.314
2017 Keifer OP, Diaz A, Campbell M, Bezchlibnyk YB, Boulis NM. Occipital Nerve Stimulation for the Treatment of Refractory Occipital Neuralgia: A Case Series. World Neurosurgery. PMID 28634063 DOI: 10.1016/J.Wneu.2017.06.064  0.304
2017 Lamanna JJ, Gutierrez J, Urquia LN, Hurtig CV, Amador E, Grin N, Svendsen CN, Federici T, Oshinski JN, Boulis NM. Ferumoxytol Labeling of Human Neural Progenitor Cells for Diagnostic Cellular Tracking in the Porcine Spinal Cord with Magnetic Resonance Imaging. Stem Cells Translational Medicine. 6: 139-150. PMID 28170192 DOI: 10.5966/Sctm.2015-0422  0.318
2017 Tora MS, Keifer OP, Lamanna JJ, Boulis NM. The challenges of developing a gene therapy for amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics. PMID 28132569 DOI: 10.1080/14737175.2017.1287565  0.306
2017 Lamanna JJ, Urquia LN, Hurtig CV, Gutierrez J, Anderson C, Piferi P, Federici T, Oshinski JN, Boulis NM. Magnetic Resonance Imaging-Guided Transplantation of Neural Stem Cells into the Porcine Spinal Cord. Stereotactic and Functional Neurosurgery. 95: 60-68. PMID 28132063 DOI: 10.1159/000448765  0.374
2016 Wagner JL, O'Connor DM, Donsante A, Boulis NM. Gene, Stem Cell, and Alternative Therapies for SCA 1. Frontiers in Molecular Neuroscience. 9: 67. PMID 27570504 DOI: 10.3389/Fnmol.2016.00067  0.332
2016 Gutierrez J, Federici T, Peterson B, Bartus R, Betourne A, Boulis NM. 321 Development of Intrathecal Riluzole: A New Route of Administration for the Treatment of Amyotrophic Lateral Sclerosis Patients. Neurosurgery. 63: 193. PMID 27399519 DOI: 10.1227/01.Neu.0000489810.52605.80  0.355
2016 Glass JD, Hertzberg VS, Boulis NM, Riley J, Polak M, Bordeau J, Fournier C, Johe K, Hazel T, Cudkowicz M, Atassi N, Borges LF, Rutkove SB, Duell J, Patil PG, et al. Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials. Neurology. PMID 27358335 DOI: 10.1212/Wnl.0000000000002889  0.356
2016 Donsante A, McEachin Z, Riley J, Leung CH, Kanz L, O'Connor DM, Boulis NM. Intracerebroventricular delivery of self-complementary adeno-associated virus serotype 9 to the adult rat brain. Gene Therapy. PMID 26824881 DOI: 10.1038/Gt.2016.6  0.533
2016 McEachin ZT, Donsante A, Boulis N. Gene Therapy for the Treatment of Neurological Disorders: Amyotrophic Lateral Sclerosis. Methods in Molecular Biology (Clifton, N.J.). 1382: 399-408. PMID 26611602 DOI: 10.1007/978-1-4939-3271-9_28  0.358
2015 Levy M, Boulis N, Rao M, Svendsen CN. Regenerative cellular therapies for neurologic diseases. Brain Research. PMID 26239912 DOI: 10.1016/J.Brainres.2015.06.053  0.33
2015 Gutierrez J, Lamanna JJ, Grin N, Hurtig CV, Miller JH, Riley J, Urquia L, Avalos P, Svendsen CN, Federici T, Boulis NM. Preclinical Validation of Multilevel Intraparenchymal Stem Cell Therapy in the Porcine Spinal Cord. Neurosurgery. 77: 604-12. PMID 26134596 DOI: 10.1227/Neu.0000000000000882  0.369
2015 O'Connor DM, Boulis NM. Gene therapy for neurodegenerative diseases. Trends in Molecular Medicine. 21: 504-12. PMID 26122838 DOI: 10.1016/J.Molmed.2015.06.001  0.345
2015 Mazzini L, Gelati M, Profico DC, Sgaravizzi G, Projetti Pensi M, Muzi G, Ricciolini C, Rota Nodari L, Carletti S, Giorgi C, Spera C, Domenico F, Bersano E, Petruzzelli F, Cisari C, ... ... Boulis NM, et al. Human neural stem cell transplantation in ALS: initial results from a phase I trial. Journal of Translational Medicine. 13: 17. PMID 25889343 DOI: 10.1186/S12967-014-0371-2  0.358
2015 Davis AS, Federici T, Ray WC, Boulis NM, O?Connor D, Clark KR, Bartlett JS. Rational design and engineering of a modified adeno-associated virus (AAV1)-based vector system for enhanced retrograde gene delivery. Neurosurgery. 76: 216-25; discussion 2. PMID 25549186 DOI: 10.1227/Neu.0000000000000589  0.4
2015 Gutierrez J, Moreton CL, Lamanna JJ, Schapiro R, Grin N, Hurtig CV, Miller JH, Riley J, Urquia L, Federici T, Boulis N. 203 Understanding Cell Migration After Direct Transplantation Into the Spinal Cord Neurosurgery. 62: 234. DOI: 10.1227/01.Neu.0000467124.38322.47  0.339
2014 Tadesse T, Gearing M, Senitzer D, Saxe D, Brat DJ, Bray R, Gebel H, Hill C, Boulis N, Riley J, Feldman E, Johe K, Hazel T, Polak M, Bordeau J, et al. Analysis of graft survival in a trial of stem cell transplant in ALS. Annals of Clinical and Translational Neurology. 1: 900-8. PMID 25540804 DOI: 10.1002/Acn3.134  0.361
2014 Keifer OP, Riley JP, Boulis NM. Deep brain stimulation for chronic pain: intracranial targets, clinical outcomes, and trial design considerations. Neurosurgery Clinics of North America. 25: 671-92. PMID 25240656 DOI: 10.1016/J.Nec.2014.07.009  0.3
2014 Feldman EL, Boulis NM, Hur J, Johe K, Rutkove SB, Federici T, Polak M, Bordeau J, Sakowski SA, Glass JD. Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: phase 1 trial outcomes. Annals of Neurology. 75: 363-73. PMID 24510776 DOI: 10.1002/Ana.24113  0.359
2014 Riley J, Glass J, Feldman EL, Polak M, Bordeau J, Federici T, Johe K, Boulis NM. Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I trial, cervical microinjection, and final surgical safety outcomes. Neurosurgery. 74: 77-87. PMID 24018694 DOI: 10.1227/Neu.0000000000000156  0.345
2013 Lamanna JJ, Miller JH, Riley JP, Hurtig CV, Boulis NM. Cellular therapeutics delivery to the spinal cord: technical considerations for clinical application. Therapeutic Delivery. 4: 1397-410. PMID 24228990 DOI: 10.4155/Tde.13.111  0.38
2013 Bethoux F, Boulis N, McClelland S, Willis MA, Hussain M, Machado A, Mychkovsky L, Stough D, Sutliff M, Pioro EP. Use of intrathecal baclofen for treatment of severe spasticity in selected patients with motor neuron disease. Neurorehabilitation and Neural Repair. 27: 828-33. PMID 23884016 DOI: 10.1177/1545968313496325  0.342
2013 Simonato M, Bennett J, Boulis NM, Castro MG, Fink DJ, Goins WF, Gray SJ, Lowenstein PR, Vandenberghe LH, Wilson TJ, Wolfe JH, Glorioso JC. Progress in gene therapy for neurological disorders. Nature Reviews. Neurology. 9: 277-91. PMID 23609618 DOI: 10.1038/Nrneurol.2013.56  0.34
2013 Boulis NM, Handy CR, Krudy CA, Donnelly EM, Federici T, Franz CK, Barrow EM, Teng Q, Kumar P, Cress D. Regulated neuronal neuromodulation via spinal cord expression of the gene for the inwardly rectifying potassium channel 2.1 (Kir2.1). Neurosurgery. 72: 653-61; discussion 6. PMID 23277370 DOI: 10.1227/Neu.0B013E318283F59A  0.695
2012 Lamanna JJ, Donnelly EM, Oshinski JN, Boulis NM, Federici T. 177 Pre-clinical Validation of Superparamagnetic Iron Oxide Nanoparticle-Labeled Neural Stem Cells for In Vivo Tracking and Post-Mortem Identification in the Spinal Cord. Neurosurgery. 71: E569. PMID 28175756 DOI: 10.1227/01.Neu.0000417765.10193.04  0.304
2012 Federici T, Hurtig CV, Burks KL, Riley JP, Krishna V, Miller BA, Sribnick EA, Miller JH, Grin N, Lamanna JJ, Boulis NM. Surgical technique for spinal cord delivery of therapies: demonstration of procedure in gottingen minipigs. Journal of Visualized Experiments : Jove. e4371. PMID 23242422 DOI: 10.3791/4371  0.382
2012 Riley J, Taub J, Raore B, Boulis NM. An overview of domestic and international clinical trials for delivery of cellular therapies to the spinal cord. Clinical Neurosurgery. 59: 98-104. PMID 22960520 DOI: 10.1227/Neu.0B013E31826B2Eee  0.357
2012 Donnelly EM, Boulis NM. Update on gene and stem cell therapy approaches for spinal muscular atrophy. Expert Opinion On Biological Therapy. 12: 1463-71. PMID 22849423 DOI: 10.1517/14712598.2012.711306  0.398
2012 Donnelly EM, Lamanna J, Boulis NM. Stem cell therapy for the spinal cord. Stem Cell Research & Therapy. 3: 24. PMID 22776143 DOI: 10.1186/Scrt115  0.378
2012 O'Connor DM, Boulis NM. Cellular and molecular approaches to motor neuron therapy in amyotrophic lateral sclerosis and spinal muscular atrophy. Neuroscience Letters. 527: 78-84. PMID 22579818 DOI: 10.1016/J.Neulet.2012.04.079  0.406
2012 Riley J, Federici T, Polak M, Kelly C, Glass J, Raore B, Taub J, Kesner V, Feldman EL, Boulis NM. Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I safety trial, technical note, and lumbar safety outcomes. Neurosurgery. 71: 405-16; discussion 4. PMID 22565043 DOI: 10.1227/Neu.0B013E31825Ca05F  0.403
2012 Glass JD, Boulis NM, Johe K, Rutkove SB, Federici T, Polak M, Kelly C, Feldman EL. Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: results of a phase I trial in 12 patients. Stem Cells (Dayton, Ohio). 30: 1144-51. PMID 22415942 DOI: 10.1002/Stem.1079  0.394
2012 Donnelly EM, Quach ET, Hillery TM, Heeke BL, Snyder BR, Handy CR, O'Connor DM, Boulis NM, Federici T. Characterization of a murine model of SMA. Neurobiology of Disease. 45: 992-8. PMID 22198571 DOI: 10.1016/J.Nbd.2011.12.018  0.39
2012 Federici T, Taub JS, Baum GR, Gray SJ, Grieger JC, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM. Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs. Gene Therapy. 19: 852-9. PMID 21918551 DOI: 10.1038/Gt.2011.130  0.426
2012 Federici T, Boulis NM. Gene therapy for amyotrophic lateral sclerosis. Neurobiology of Disease. 48: 236-42. PMID 21889591 DOI: 10.1016/J.Nbd.2011.08.018  0.356
2012 Riley J, Hurtig CV, Boulis N. Translating cellular therapies from bench to bedside for amyotrophic lateral sclerosis Personalized Medicine. 9: 645-655. DOI: 10.2217/Pme.12.74  0.319
2011 Boulis NM, Federici T, Glass JD, Lunn JS, Sakowski SA, Feldman EL. Translational stem cell therapy for amyotrophic lateral sclerosis. Nature Reviews. Neurology. 8: 172-6. PMID 22158518 DOI: 10.1038/Nrneurol.2011.191  0.328
2011 Kliem MA, Heeke BL, Franz CK, Radovitskiy I, Raore B, Barrow E, Snyder BR, Federici T, Kaye Spratt S, Boulis NM. Intramuscular administration of a VEGF zinc finger transcription factor activator (VEGF-ZFP-TF) improves functional outcomes in SOD1 rats. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 331-9. PMID 21864053 DOI: 10.3109/17482968.2011.574142  0.672
2011 Leung CH, Kliem MA, Heeke BL, McPhee SW, Federici T, Snyder BR, Boulis NM. Assessment of hippocampal adeno-associated viral vector gene delivery via frameless stereotaxis in a nonhuman primate. Stereotactic and Functional Neurosurgery. 89: 275-85. PMID 21849811 DOI: 10.1159/000328265  0.526
2011 Boulis N, Federici T. Surgical approach and safety of spinal cord stem cell transplantation Neurosurgery. 68: E599-E600. PMID 21654562 DOI: 10.1227/Neu.0B013E3182095E2E  0.34
2011 Riley JP, Raore B, Taub JS, Federici T, Boulis NM. Platform and cannula design improvements for spinal cord therapeutics delivery. Neurosurgery. 69: ons147-54; discussio. PMID 21471842 DOI: 10.1227/Neu.0B013E3182195680  0.369
2011 Snyder BR, Gray SJ, Quach ET, Huang JW, Leung CH, Samulski RJ, Boulis NM, Federici T. Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery. Human Gene Therapy. 22: 1129-35. PMID 21443428 DOI: 10.1089/Hum.2011.008  0.588
2011 Lunn JS, Sakowski SA, Federici T, Glass JD, Boulis NM, Feldman EL. Stem cell technology for the study and treatment of motor neuron diseases. Regenerative Medicine. 6: 201-13. PMID 21391854 DOI: 10.2217/Rme.11.6  0.353
2011 Raore B, Federici T, Taub J, Wu MC, Riley J, Franz CK, Kliem MA, Snyder B, Feldman EL, Johe K, Boulis NM. Cervical multilevel intraspinal stem cell therapy: assessment of surgical risks in Gottingen minipigs. Spine. 36: E164-71. PMID 21099736 DOI: 10.1097/Brs.0B013E3181D77A47  0.71
2011 Lunn JS, Sakowski SA, Federici T, Glass JD, Boulis NM, Feldman EL. Erratum: Stem cell technology for the study and treatment of motor neuron diseases, which appeared in the February issue of Regenerative Medicine (Regen. Med. (2011) 6:2 (201-213)) Regenerative Medicine. 6. DOI: 10.2217/Rme.11.30  0.319
2010 Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, et al. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. The Lancet. Neurology. 9: 1164-72. PMID 20970382 DOI: 10.1016/S1474-4422(10)70254-4  0.32
2010 Snyder BR, Boulis NM, Federici T. Viral vector-mediated gene transfer for CNS disease. Expert Opinion On Biological Therapy. 10: 381-94. PMID 20132059 DOI: 10.1517/14712590903514074  0.339
2009 Federici T, Riley J, Park J, Bain M, Boulis NM. Preclinical safety validation of a stabilized viral vector direct injection approach to the cervical spinal cord Clinical and Translational Science. 2: 165-167. PMID 20443884 DOI: 10.1111/J.1752-8062.2008.00084.X  0.384
2009 Federici T, Boulis NM. Invited review: festschrift edition of neurosurgery peripheral nervous system as a conduit for delivering therapies for diabetic neuropathy, amyotrophic lateral sclerosis, and nerve regeneration. Neurosurgery. 65: A87-92. PMID 19927084 DOI: 10.1227/01.Neu.0000335653.52938.F2  0.344
2009 Riley J, Federici T, Park J, Suzuki M, Franz CK, Tork C, McHugh J, Teng Q, Svendsen C, Boulis NM. Cervical spinal cord therapeutics delivery: preclinical safety validation of a stabilized microinjection platform. Neurosurgery. 65: 754-61; discussion 7. PMID 19834381 DOI: 10.1227/01.Neu.0000343524.45387.9E  0.678
2009 Franz CK, Quach ET, Krudy CA, Federici T, Kliem MA, Snyder BR, Raore B, Boulis NM. A conditioning lesion provides selective protection in a rat model of Amyotrophic Lateral Sclerosis. Plos One. 4: e7357. PMID 19806196 DOI: 10.1371/Journal.Pone.0007357  0.668
2009 Federici T, Kutner R, Zhang XY, Kuroda H, Tordo N, Boulis NM, Reiser J. Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus glycoproteins for neuronal gene transfer. Genetic Vaccines and Therapy. 7: 1. PMID 19144125 DOI: 10.1186/1479-0556-7-1  0.383
2009 Franz CK, Federici T, Yang J, Backus C, Oh SS, Teng Q, Carlton E, Bishop KM, Gasmi M, Bartus RT, Feldman EL, Boulis NM. Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. Neurobiology of Disease. 33: 473-81. PMID 19135533 DOI: 10.1016/J.Nbd.2008.12.003  0.703
2009 Federici T, Riley J, Boulis N. Gene-Based Neuromodulation Neuromodulation. 1: 131-141. DOI: 10.1016/B978-0-12-374248-3.00014-8  0.338
2008 Carlton E, Teng Q, Federici T, Yang J, Riley J, Boulis NM. Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons. Neurosurgery. 63: 1175-82; discussion . PMID 19057331 DOI: 10.1227/01.Neu.0000334415.45003.Ea  0.359
2008 Riley J, Sweeney W, Boulis N. Shifting the balance: cell-based therapeutics as modifiers of the amyotrophic lateral sclerosis-specific neuronal microenvironment. Neurosurgical Focus. 24: E10. PMID 18341386 DOI: 10.3171/Foc/2008/24/3-4/E9  0.333
2008 Riley J, Butler J, Baker KB, McClelland S, Teng Q, Yang J, Garrity-Moses M, Federici T, Boulis NM. Targeted spinal cord therapeutics delivery: stabilized platform and microelectrode recording guidance validation. Stereotactic and Functional Neurosurgery. 86: 67-74. PMID 18073518 DOI: 10.1159/000112426  0.384
2007 Federici T, Boulis N. Gene therapy for peripheral nervous system diseases. Current Gene Therapy. 7: 239-48. PMID 17969557 DOI: 10.2174/156652307781369083  0.344
2007 Yang J, Teng Q, Garrity-Moses ME, McClelland S, Federici T, Carlton E, Riley J, Boulis NM. Reversible unilateral nigrostriatal pathway inhibition induced through expression of adenovirus-mediated clostridial light chain gene in the substantia nigra. Neuromolecular Medicine. 9: 276-84. PMID 17914186 DOI: 10.1007/S12017-007-8003-0  0.305
2007 Alexopoulos AV, Gonugunta V, Yang J, Boulis NM. Electrical stimulation and gene-based neuromodulation for control of medically-refractory epilepsy. Acta Neurochirurgica. Supplement. 97: 293-309. PMID 17691316 DOI: 10.1007/978-3-211-33081-4_33  0.307
2007 Federici T, Liu JK, Teng Q, Yang J, Boulis NM. A means for targeting therapeutics to peripheral nervous system neurons with axonal damage. Neurosurgery. 60: 911-8; discussion 91. PMID 17460527 DOI: 10.1227/01.Neu.0000255444.44365.B9  0.359
2007 McClelland S, Teng Q, Benson LS, Boulis NM. Motor neuron inhibition-based gene therapy for spasticity. American Journal of Physical Medicine & Rehabilitation / Association of Academic Physiatrists. 86: 412-21. PMID 17449986 DOI: 10.1097/Phm.0B013E31804A83Cf  0.393
2007 Federici T, Boulis NM. Ribonucleic acid interference for neurological disorders: candidate diseases, potential targets, and current approaches. Neurosurgery. 60: 3-15; discussion 15-. PMID 17228249 DOI: 10.1227/01.Neu.0000249214.42461.A5  0.312
2007 Yang J, Teng Q, Federici T, Najm I, Chabardes S, Moffitt M, Alexopoulos A, Riley J, Boulis NM. Viral clostridial light chain gene-based control of penicillin-induced neocortical seizures. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 542-51. PMID 17213837 DOI: 10.1038/Sj.Mt.6300069  0.313
2006 Garrity-Moses ME, Teng Q, Krudy C, Yang J, Federici T, Boulis NM. X-Linked inhibitor of apoptosis protein gene-based neuroprotection for the peripheral nervous system. Neurosurgery. 59: 172-82; discussion 1. PMID 16823314 DOI: 10.1227/01.Neu.0000219237.69329.B7  0.347
2006 Zhao Z, Krishnaney A, Teng Q, Yang J, Garrity-Moses M, Liu JK, Venkiteswaran K, Subramanian T, Davis M, Boulis NM. Anatomically discrete functional effects of adenoviral clostridial light chain gene-based synaptic inhibition in the midbrain. Gene Therapy. 13: 942-52. PMID 16511525 DOI: 10.1038/Sj.Gt.3302733  0.444
2006 Federici T, Boulis NM. Gene-based treatment of motor neuron diseases. Muscle & Nerve. 33: 302-23. PMID 16228969 DOI: 10.1002/Mus.20439  0.404
2006 Teng Q, Bartlett J, Federici T, Yang J, Boulis N. 500. Tetanus Toxin Heavy Chain-Streptoavidin Fusion Protein for Targeted Motor Neuron Gene Delivery through Metabolically Biotinylated AAV Molecular Therapy. 13: S193. DOI: 10.1016/J.Ymthe.2006.08.570  0.339
2006 Yang J, Teng Q, Garrity-Moses ME, Federici T, Butler J, McClelland S, Boulis NM. 240. Hemiparkisonism Induced through Unilateral Expression of Adenovirus-Mediated Clostridial Light Chain Gene in the Substantia Nigra Molecular Therapy. 13: S92. DOI: 10.1016/J.Ymthe.2006.08.267  0.301
2005 Garrity-Moses ME, Teng Q, Liu J, Tanase D, Boulis NM. Neuroprotective adeno-associated virus Bcl-xL gene transfer in models of motor neuron disease. Muscle & Nerve. 32: 734-44. PMID 16116646 DOI: 10.1002/Mus.20418  0.355
2005 Liu JK, Teng Q, Garrity-Moses M, Federici T, Tanase D, Imperiale MJ, Boulis NM. A novel peptide defined through phage display for therapeutic protein and vector neuronal targeting. Neurobiology of Disease. 19: 407-18. PMID 16023583 DOI: 10.1016/J.Nbd.2005.01.022  0.307
2005 Teng Q, Garrity-Moses M, Federici T, Tanase D, Liu JK, Mazarakis ND, Azzouz M, Walmsley LE, Carlton E, Boulis NM. Trophic activity of Rabies G protein-pseudotyped equine infectious anemia viral vector mediated IGF-I motor neuron gene transfer in vitro. Neurobiology of Disease. 20: 694-700. PMID 16005636 DOI: 10.1016/J.Nbd.2005.05.016  0.339
2005 Teng Q, Tanase D, Tanase DK, Liu JK, Garrity-Moses ME, Baker KB, Boulis NM. Adenoviral clostridial light chain gene-based synaptic inhibition through neuronal synaptobrevin elimination. Gene Therapy. 12: 108-19. PMID 15496959 DOI: 10.1038/Sj.Gt.3302400  0.385
2005 Federici T, Liu JK, Teng Q, Garrity-Moses M, Yang J, Boulis NM. 855. In Vivo Spinal Cord Uptake and Neuronal Binding Properties of Tet1: A Potential Means for Enhanced Spinal Cord AAV Delivery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.398  0.358
2005 Davis A, Stachler M, Shi W, Liu J, Boulis N, Bartlett J. 113. Manipulating AAV2 Tropism for Enhanced Delivery of AAV Vectors to the Spinal Cord Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.118  0.421
2004 Vincent AM, Feldman EL, Song DK, Jung V, Schild A, Zhang W, Imperiale MJ, Boulis NM. Adeno-associated viral-mediated insulin-like growth factor delivery protects motor neurons in vitro. Neuromolecular Medicine. 6: 79-85. PMID 15970625 DOI: 10.1385/Nmm:6:2-3:079  0.376
2004 Tanase K, Teng Q, Krishnaney AA, Liu JK, Garrity-Moses ME, Boulis NM. Cervical spinal cord delivery of a rabies G protein pseudotyped lentiviral vector in the SOD-1 transgenic mouse. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004. Journal of Neurosurgery. Spine. 1: 128-36. PMID 15291033 DOI: 10.3171/Spi.2004.1.1.0128  0.403
2004 Teng Q, Garrity-Moses M, Liu JK, Tanase D, Azzouz M, Walmsley L, Mazarakis ND, Boulis NM. 735. EIAV-IGF-I Gene Transfer to Motor Neurons Enhances Axonal Length In Vitro Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.679  0.392
2004 Tanase D, Teng Q, Krishnaney AA, Liu JK, Garrity-Moses ME, Mazarakis N, Walmsley LE, Azzouz M, Boulis NM. 532. Cervical Spinal Cord Delivery of a Lentiviral Vector in SOD-1 Transgenic Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.479  0.416
2004 Krishnaney AA, Zhao Z, Teng Q, Liu J, Tenase D, Garrity-Moses M, Davis M, Boulis NM. 45. Adenoviral tetanus toxin light chain gene expression in the brainstem induces specific motor inhibition Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.067  0.447
2003 Boulis NM, Noordmans AJ, Song DK, Imperiale MJ, Rubin A, Leone P, During M, Feldman EL. Adeno-associated viral vector gene expression in the adult rat spinal cord following remote vector delivery. Neurobiology of Disease. 14: 535-41. PMID 14678769 DOI: 10.1016/J.Nbd.2003.08.025  0.41
2003 Garrity-Moses ME, Liu JK, Boulis NM. Molecular biology and gene therapy in the treatment of chronic pain. Neurosurgery Clinics of North America. 14: 419-35. PMID 14567143 DOI: 10.1016/S1042-3680(03)00008-1  0.338
2003 Rubin A, Mobley B, Hogikyan N, Bell K, Sullivan K, Boulis N, Feldman E. Delivery of an adenoviral vector to the crushed recurrent laryngeal nerve. The Laryngoscope. 113: 985-9. PMID 12782809 DOI: 10.1097/00005537-200306000-00013  0.331
2003 Boulis NM, Willmarth NE, Song DK, Feldman EL, Imperiale MJ. Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery. Neurosurgery. 52: 381-7; discussion 38. PMID 12535368 DOI: 10.1227/01.Neu.0000044459.24519.3E  0.387
2002 Boulis NM, Turner DE, Imperiale MJ, Feldman EL. Neuronal survival following remote adenovirus gene delivery. Journal of Neurosurgery. 96: 212-9. PMID 12450285 DOI: 10.3171/Spi.2002.96.2.0212  0.405
2001 Turner DE, Noordmans AJ, Feldman EL, Boulis NM. Remote adenoviral gene delivery to the spinal cord: contralateral delivery and reinjection. Neurosurgery. 48: 1309-16; discussion . PMID 11383735 DOI: 10.1097/00006123-200106000-00026  0.397
1999 Boulis NM, Turner DE, Dice JA, Bhatia V, Feldman EL. Characterization of adenoviral gene expression in spinal cord after remote vector delivery. Neurosurgery. 45: 131-7; discussion 13. PMID 10414575 DOI: 10.1097/00006123-199907000-00029  0.397
1999 Boulis NM, Bhatia V, Brindle TI, Holman HT, Krauss DJ, Blaivas M, Hoff JT. Adenoviral nerve growth factor and beta-galactosidase transfer to spinal cord: a behavioral and histological analysis. Journal of Neurosurgery. 90: 99-108. PMID 10413133 DOI: 10.3171/Spi.1999.90.1.0099  0.398
1991 Kehne JH, Boulis NM, Davis M. Effects of the phosphodiesterase inhibitor rolipram on the acoustic startle response in rats. Psychopharmacology. 105: 27-36. PMID 1660609 DOI: 10.1007/Bf02316860  0.454
1990 Boulis NM, Davis M. Blockade of the spinal excitatory effect of cAMP on the startle reflex by intrathecal administration of the isoquinoline sulfonamide H-8: comparison to the protein kinase C inhibitor H-7. Brain Research. 525: 198-204. PMID 2174710 DOI: 10.1016/0006-8993(90)90864-8  0.401
1990 Boulis NM, Kehne JH, Miserendino MJ, Davis M. Differential blockade of early and late components of acoustic startle following intrathecal infusion of 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) or D,L-2-amino-5-phosphonovaleric acid (AP-5). Brain Research. 520: 240-6. PMID 1976408 DOI: 10.1016/0006-8993(90)91711-O  0.405
1989 Davis M, Commissaris RL, Yang S, Wagner KR, Kehne JH, Cassella JV, Boulis NM. Spinal vs. supraspinal sites of action of the alpha 2-adrenergic agonists clonidine and ST-91 on the acoustic startle reflex. Pharmacology, Biochemistry, and Behavior. 33: 233-40. PMID 2571168 DOI: 10.1016/0091-3057(89)90455-3  0.4
1989 Boulis NM, Davis M. Footshock-induced sensitization of electrically elicited startle reflexes. Behavioral Neuroscience. 103: 504-508. PMID 2544200 DOI: 10.1037//0735-7044.103.3.504  0.426
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