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William R. Markesbery, MD, University of Kentucky - Publications

Affiliations: 
Pathology University of Kentucky, Lexington, KY 
Area:
neurology, oxidative stress, Alzheimer disease
Website:
http://www.research.uky.edu/odyssey/spring10/markesbery.html
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236 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Iacono D, Zandi P, Gross M, Markesbery WR, Pletnikova O, Rudow G, Troncoso JC. APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study. Oncotarget. 6: 14082-91. PMID 26101858  0.52
2015 Rahman-Filipiak A, Woodard JL, Miller LS, Martin P, Davey A, Poon LW. Octogenarian and centenarian performance on the Fuld Object Memory Evaluation. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition. 22: 438-51. PMID 25513737 DOI: 10.1080/13825585.2014.968085  0.52
2015 Cho J, Martin P, Poon LW. Successful aging and subjective well-being among oldest-old adults. The Gerontologist. 55: 132-43. PMID 25112594 DOI: 10.1093/geront/gnu074  0.52
2015 Davey A, Siegler IC, Martin P, Costa PT, Poon LW, Jazwinski SM, Woodard JL, Miller LS, Johnson MA, Hausman DB, MacDonald M, Gearing M, Green RC, Markesbery WR, Rodgers WL, et al. Personality Structure Among Centenarians: The Georgia Centenarian Study Experimental Aging Research. 41: 361-385. DOI: 10.1080/0361073X.2015.1053752  0.52
2013 Bains M, Cebak JE, Gilmer LK, Barnes CC, Thompson SN, Geddes JW, Hall ED, Markesbery WR. Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ-1945 in a mouse traumatic brain injury model Journal of Neurochemistry. 125: 125-132. PMID 23216523 DOI: 10.1111/jnc.12118  0.52
2012 Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE, ... ... Markesbery WR, et al. Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease. Aging Cell. 11: 559-68. PMID 22404891 DOI: 10.1111/j.1474-9726.2012.00817.x  0.52
2012 Ding Q, Zhu H, Zhang B, Soriano A, Burns R, Markesbery WR. Increased 5S rRNA oxidation in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 29: 201-9. PMID 22232003 DOI: 10.3233/JAD-2012-111058  0.52
2012 Bradley MA, Xiong-Fister S, Markesbery WR, Lovell MA. Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression. Neurobiology of Aging. 33: 1034-44. PMID 20965613 DOI: 10.1016/j.neurobiolaging.2010.08.016  0.52
2012 Gleichmann M, Zhang Y, Wood WH, Becker KG, Mughal MR, Pazin MJ, van Praag H, Kobilo T, Zonderman AB, Troncoso JC, Markesbery WR, Mattson MP. Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks. Neurobiology of Aging. 33: 205.e1-18. PMID 20947216 DOI: 10.1016/j.neurobiolaging.2010.08.012  0.52
2011 Robinson RA, Joshi G, Huang Q, Sultana R, Baker AS, Cai J, Pierce W, St Clair DK, Markesbery WR, Butterfield DA. Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease. Proteomics. 11: 4243-56. PMID 21954051 DOI: 10.1002/pmic.201000523  0.52
2011 Sultana R, Robinson RA, Di Domenico F, Abdul HM, St Clair DK, Markesbery WR, Cai J, Pierce WM, Butterfield DA. Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age. Journal of Proteomics. 74: 2430-40. PMID 21726674 DOI: 10.1016/j.jprot.2011.06.015  0.52
2011 Aluise CD, Robinson RA, Cai J, Pierce WM, Markesbery WR, Butterfield DA. Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI. Journal of Alzheimer's Disease : Jad. 23: 257-69. PMID 20930294 DOI: 10.3233/JAD-2010-101083  0.52
2011 Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, et al. Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiology of Aging. 32: 2113-22. PMID 20452100 DOI: 10.1016/j.neurobiolaging.2010.01.010  0.52
2010 Ebenezer PJ, Weidner AM, LeVine H, Markesbery WR, Murphy MP, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Gavilán E, Keller JN. Neuron specific toxicity of oligomeric amyloid-β: role for JUN-kinase and oxidative stress. Journal of Alzheimer's Disease : Jad. 22: 839-48. PMID 20858948 DOI: 10.3233/JAD-2010-101161  0.52
2010 Huang Q, Aluise CD, Joshi G, Sultana R, St Clair DK, Markesbery WR, Butterfield DA. Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment. Journal of Neuroscience Research. 88: 2618-29. PMID 20648652 DOI: 10.1002/jnr.22422  0.52
2010 Nelson PT, Schmitt FA, Jicha GA, Kryscio RJ, Abner EL, Smith CD, Van Eldik LJ, Markesbery WR. Association between male gender and cortical Lewy body pathology in large autopsy series. Journal of Neurology. 257: 1875-81. PMID 20563821 DOI: 10.1007/s00415-010-5630-4  0.52
2010 Aluise CD, Robinson RA, Beckett TL, Murphy MP, Cai J, Pierce WM, Markesbery WR, Butterfield DA. Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics. Neurobiology of Disease. 39: 221-8. PMID 20399861 DOI: 10.1016/j.nbd.2010.04.011  0.52
2010 Jicha GA, Markesbery WR. Omega-3 fatty acids: potential role in the management of early Alzheimer's disease. Clinical Interventions in Aging. 5: 45-61. PMID 20396634  0.52
2010 Dasuri K, Ebenezer P, Zhang L, Fernandez-Kim SO, Bruce-Keller AJ, Markesbery WR, Keller JN. Increased protein hydrophobicity in response to aging and Alzheimer disease. Free Radical Biology & Medicine. 48: 1330-7. PMID 20188163 DOI: 10.1016/j.freeradbiomed.2010.02.012  0.52
2010 Bradley MA, Markesbery WR, Lovell MA. Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free Radical Biology & Medicine. 48: 1570-6. PMID 20171275 DOI: 10.1016/j.freeradbiomed.2010.02.016  0.52
2010 Bader Lange ML, St Clair D, Markesbery WR, Studzinski CM, Murphy MP, Butterfield DA. Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease. Neurobiology of Disease. 38: 104-15. PMID 20083199 DOI: 10.1016/j.nbd.2010.01.004  0.52
2010 Lynn BC, Wang J, Markesbery WR, Lovell MA. Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 325-39. PMID 20061648 DOI: 10.3233/JAD-2010-1254  0.52
2010 Markesbery WR. Neuropathologic alterations in mild cognitive impairment: a review. Journal of Alzheimer's Disease : Jad. 19: 221-8. PMID 20061641 DOI: 10.3233/JAD-2010-1220  0.52
2010 Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H, Keller JN, Markesbery WR. NOX activity is increased in mild cognitive impairment. Antioxidants & Redox Signaling. 12: 1371-82. PMID 19929442 DOI: 10.1089/ars.2009.2823  0.52
2010 Nelson PT, Jicha GA, Kryscio RJ, Abner EL, Schmitt FA, Cooper G, Xu LO, Smith CD, Markesbery WR. Low sensitivity in clinical diagnoses of dementia with Lewy bodies. Journal of Neurology. 257: 359-66. PMID 19795154 DOI: 10.1007/s00415-009-5324-y  0.52
2010 Carr SA, Davis R, Spencer D, Smart M, Hudson J, Freeman S, Cooper GE, Schmitt FA, Markesbery WR, Danner D, Jicha GA. Comparison of recruitment efforts targeted at primary care physicians versus the community at large for participation in Alzheimer disease clinical trials. Alzheimer Disease and Associated Disorders. 24: 165-70. PMID 19571728 DOI: 10.1097/WAD.0b013e3181aba927  0.52
2010 Lyubartseva G, Smith JL, Markesbery WR, Lovell MA. Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain. Brain Pathology (Zurich, Switzerland). 20: 343-50. PMID 19371353 DOI: 10.1111/j.1750-3639.2009.00283.x  0.52
2010 Jicha GA, Schmitt FA, Abner E, Nelson PT, Cooper GE, Smith CD, Markesbery WR. Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease. Neurobiology of Aging. 31: 1805-13. PMID 19026468 DOI: 10.1016/j.neurobiolaging.2008.09.017  0.52
2010 Nelson PT, Abner EL, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Davis DG, Poduska JW, Patel E, Mendiondo MS, Markesbery WR. Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathology (Zurich, Switzerland). 20: 66-79. PMID 19021630 DOI: 10.1111/j.1750-3639.2008.00244.x  0.52
2010 Jo DG, Arumugam TV, Woo HN, Park JS, Tang SC, Mughal M, Hyun DH, Park JH, Choi YH, Gwon AR, Camandola S, Cheng A, Cai H, Song W, Markesbery WR, et al. Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease. Neurobiology of Aging. 31: 917-25. PMID 18687504 DOI: 10.1016/j.neurobiolaging.2008.07.003  0.52
2009 Grear KE, Ling IF, Simpson JF, Furman JL, Simmons CR, Peterson SL, Schmitt FA, Markesbery WR, Liu Q, Crook JE, Younkin SG, Bu G, Estus S. Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain. Molecular Neurodegeneration. 4: 46. PMID 19889229 DOI: 10.1186/1750-1326-4-46  0.52
2009 Nelson PT, Kryscio RJ, Jicha GA, Abner EL, Schmitt FA, Xu LO, Cooper G, Smith CD, Markesbery WR. Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies. Neurology. 73: 1127-33. PMID 19805729 DOI: 10.1212/WNL.0b013e3181bacf9e  0.52
2009 Iacono D, Markesbery WR, Gross M, Pletnikova O, Rudow G, Zandi P, Troncoso JC. The Nun study: clinically silent AD, neuronal hypertrophy, and linguistic skills in early life. Neurology. 73: 665-73. PMID 19587326 DOI: 10.1212/WNL.0b013e3181b01077  0.52
2009 Nelson PT, Abner EL, Schmitt FA, Kryscio RJ, Jicha GA, Santacruz K, Smith CD, Patel E, Markesbery WR. Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 68: 774-84. PMID 19535994 DOI: 10.1097/NEN.0b013e3181aacbe9  0.52
2009 Markesbery WR, Jicha GA, Liu H, Schmitt FA. Lewy body pathology in normal elderly subjects. Journal of Neuropathology and Experimental Neurology. 68: 816-22. PMID 19535990 DOI: 10.1097/NEN.0b013e3181ac10a7  0.52
2009 Mortimer JA, Snowdon DA, Markesbery WR. The effect of APOE-epsilon4 on dementia is mediated by Alzheimer neuropathology. Alzheimer Disease and Associated Disorders. 23: 152-7. PMID 19484916 DOI: 10.1097/WAD.0b013e318190a855  0.52
2009 Price JL, McKeel DW, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, et al. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiology of Aging. 30: 1026-36. PMID 19376612 DOI: 10.1016/j.neurobiolaging.2009.04.002  0.52
2009 Reed TT, Pierce WM, Markesbery WR, Butterfield DA. Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD. Brain Research. 1274: 66-76. PMID 19374891 DOI: 10.1016/j.brainres.2009.04.009  0.52
2009 Lovell MA, Xiong S, Lyubartseva G, Markesbery WR. Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radical Biology & Medicine. 46: 1527-33. PMID 19303433 DOI: 10.1016/j.freeradbiomed.2009.03.008  0.52
2009 Nelson PT, Kryscio RJ, Abner EL, Schmitt FA, Jicha GA, Mendiondo MS, Cooper G, Smith CB, Markesbery WR. Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB. Journal of Alzheimer's Disease : Jad. 16: 29-34. PMID 19158418 DOI: 10.3233/JAD-2009-0926  0.52
2009 Nelson PT, Braak H, Markesbery WR. Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship. Journal of Neuropathology and Experimental Neurology. 68: 1-14. PMID 19104448 DOI: 10.1097/NEN.0b013e3181919a48  0.52
2009 Studzinski CM, Li F, Bruce-Keller AJ, Fernandez-Kim SO, Zhang L, Weidner AM, Markesbery WR, Murphy MP, Keller JN. Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice. Journal of Neurochemistry. 108: 860-6. PMID 19046405 DOI: 10.1111/j.1471-4159.2008.05798.x  0.52
2009 Nelson PT, Abner EL, Scheff SW, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Patel E, Markesbery WR. Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment. Neuroscience Letters. 450: 336-9. PMID 19010392 DOI: 10.1016/j.neulet.2008.11.006  0.52
2009 Nelson PT, Smith CD, Abner EA, Schmitt FA, Scheff SW, Davis GJ, Keller JN, Jicha GA, Davis D, Wang-Xia W, Hartman A, Katz DG, Markesbery WR. Human cerebral neuropathology of Type 2 diabetes mellitus. Biochimica Et Biophysica Acta. 1792: 454-69. PMID 18789386 DOI: 10.1016/j.bbadis.2008.08.005  0.52
2009 Reed TT, Pierce WM, Turner DM, Markesbery WR, Butterfield DA. Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule. Journal of Cellular and Molecular Medicine. 13: 2019-29. PMID 18752637 DOI: 10.1111/j.1582-4934.2008.00478.x  0.52
2008 Dong J, Robertson JD, Markesbery WR, Lovell MA. Serum zinc in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 15: 443-50. PMID 18997297  0.52
2008 Smith CD, Chebrolu H, Markesbery WR, Liu J. Improved predictive model for pre-symptomatic mild cognitive impairment and Alzheimer's disease. Neurological Research. 30: 1091-6. PMID 18768112 DOI: 10.1179/174313208X327973  0.52
2008 Abdul HM, Sultana R, St Clair DK, Markesbery WR, Butterfield DA. Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age. Free Radical Biology & Medicine. 45: 1420-5. PMID 18762245 DOI: 10.1016/j.freeradbiomed.2008.08.012  0.52
2008 Jicha GA, Abner E, Schmitt FA, Cooper GE, Stiles N, Hamon R, Carr S, Smith CD, Markesbery WR. Clinical features of mild cognitive impairment differ in the research and tertiary clinic settings. Dementia and Geriatric Cognitive Disorders. 26: 187-92. PMID 18724049 DOI: 10.1159/000151635  0.52
2008 Shao C, Xiong S, Li GM, Gu L, Mao G, Markesbery WR, Lovell MA. Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain. Free Radical Biology & Medicine. 45: 813-9. PMID 18598755 DOI: 10.1016/j.freeradbiomed.2008.06.003  0.52
2008 Tang SC, Lathia JD, Selvaraj PK, Jo DG, Mughal MR, Cheng A, Siler DA, Markesbery WR, Arumugam TV, Mattson MP. Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Experimental Neurology. 213: 114-21. PMID 18586243 DOI: 10.1016/j.expneurol.2008.05.014  0.52
2008 Mortimer JA, Snowdon DA, Markesbery WR. Small head circumference is associated with less education in persons at risk for Alzheimer disease in later life. Alzheimer Disease and Associated Disorders. 22: 249-54. PMID 18580587 DOI: 10.1097/WAD.0b013e318170d455  0.52
2008 Sonnen JA, Breitner JC, Lovell MA, Markesbery WR, Quinn JF, Montine TJ. Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models. Free Radical Biology & Medicine. 45: 219-30. PMID 18482592 DOI: 10.1016/j.freeradbiomed.2008.04.022  0.52
2008 Lovell MA, Lynn BC, Xiong S, Quinn JF, Kaye J, Markesbery WR. An aberrant protein complex in CSF as a biomarker of Alzheimer disease. Neurology. 70: 2212-8. PMID 18448869 DOI: 10.1212/01.wnl.0000312383.39973.88  0.52
2008 Reed T, Perluigi M, Sultana R, Pierce WM, Klein JB, Turner DM, Coccia R, Markesbery WR, Butterfield DA. Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiology of Disease. 30: 107-20. PMID 18325775 DOI: 10.1016/j.nbd.2007.12.007  0.52
2008 Lovell MA, Markesbery WR. Oxidatively modified RNA in mild cognitive impairment. Neurobiology of Disease. 29: 169-75. PMID 17920285 DOI: 10.1016/j.nbd.2007.07.030  0.52
2007 Nelson PT, Jicha GA, Schmitt FA, Liu H, Davis DG, Mendiondo MS, Abner EL, Markesbery WR. Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity. Journal of Neuropathology and Experimental Neurology. 66: 1136-46. PMID 18090922 DOI: 10.1097/nen.0b013e31815c5efb  0.52
2007 Youn H, Ji I, Ji HP, Markesbery WR, Ji TH. Under-expression of Kalirin-7 Increases iNOS activity in cultured cells and correlates to elevated iNOS activity in Alzheimer's disease hippocampus. Journal of Alzheimer's Disease : Jad. 12: 271-81. PMID 18057561  0.52
2007 Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Research. 35: 7497-504. PMID 17947327 DOI: 10.1093/nar/gkm821  0.52
2007 Tyas SL, Snowdon DA, Desrosiers MF, Riley KP, Markesbery WR. Healthy ageing in the Nun Study: definition and neuropathologic correlates. Age and Ageing. 36: 650-5. PMID 17906306 DOI: 10.1093/ageing/afm120  0.52
2007 Youn H, Jeoung M, Koo Y, Ji H, Markesbery WR, Ji I, Ji TH. Kalirin is under-expressed in Alzheimer's disease hippocampus. Journal of Alzheimer's Disease : Jad. 11: 385-97. PMID 17851188  0.52
2007 Weissman L, Jo DG, Sørensen MM, de Souza-Pinto NC, Markesbery WR, Mattson MP, Bohr VA. Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. Nucleic Acids Research. 35: 5545-55. PMID 17704129 DOI: 10.1093/nar/gkm605  0.52
2007 Murphy MP, Beckett TL, Ding Q, Patel E, Markesbery WR, St Clair DK, LeVine H, Keller JN. Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice. Neurobiology of Disease. 27: 301-11. PMID 17651976 DOI: 10.1016/j.nbd.2007.06.002  0.52
2007 Markesbery WR, Lovell MA. Damage to lipids, proteins, DNA, and RNA in mild cognitive impairment. Archives of Neurology. 64: 954-6. PMID 17620484 DOI: 10.1001/archneur.64.7.954  0.32
2007 Lovell MA, Markesbery WR. Oxidative damage in mild cognitive impairment and early Alzheimer's disease. Journal of Neuroscience Research. 85: 3036-40. PMID 17510979 DOI: 10.1002/jnr.21346  0.52
2007 Smith CD, Chebrolu H, Wekstein DR, Schmitt FA, Jicha GA, Cooper G, Markesbery WR. Brain structural alterations before mild cognitive impairment. Neurology. 68: 1268-73. PMID 17438217 DOI: 10.1212/01.wnl.0000259542.54830.34  0.52
2007 Mao G, Pan X, Zhu BB, Zhang Y, Yuan F, Huang J, Lovell MA, Lee MP, Markesbery WR, Li GM, Gu L. Identification and characterization of OGG1 mutations in patients with Alzheimer's disease. Nucleic Acids Research. 35: 2759-66. PMID 17426120 DOI: 10.1093/nar/gkm189  0.52
2007 Butterfield DA, Reed TT, Perluigi M, De Marco C, Coccia R, Keller JN, Markesbery WR, Sultana R. Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease. Brain Research. 1148: 243-8. PMID 17395167 DOI: 10.1016/j.brainres.2007.02.084  0.52
2007 Xiong S, Markesbery WR, Shao C, Lovell MA. Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death. Antioxidants & Redox Signaling. 9: 457-67. PMID 17280487 DOI: 10.1089/ars.2006.1363  0.52
2007 Neumann M, Mackenzie IR, Cairns NJ, Boyer PJ, Markesbery WR, Smith CD, Taylor JP, Kretzschmar HA, Kimonis VE, Forman MS. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. Journal of Neuropathology and Experimental Neurology. 66: 152-7. PMID 17279000 DOI: 10.1097/nen.0b013e31803020b9  0.52
2007 Smith CD, Chebrolu H, Wekstein DR, Schmitt FA, Markesbery WR. Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly. Neurobiology of Aging. 28: 1075-87. PMID 16774798 DOI: 10.1016/j.neurobiolaging.2006.05.018  0.52
2007 Kryscio RJ, Schmitt FA, Mendiondo MS, Markesbery WR. Hypertension as a risk factor for transitions from normal to dementia or mild cognitive impairment Research and Practice in Alzheimer's Disease. 12: 139-143.  0.52
2006 Markesbery WR. Commentary on "Vascular cognitive impairment: today and tomorrow". Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 205-6. PMID 19595887 DOI: 10.1016/j.jalz.2006.04.004  0.52
2006 Markesbery WR, Lovell MA. DNA oxidation in Alzheimer's disease. Antioxidants & Redox Signaling. 8: 2039-45. PMID 17034348 DOI: 10.1089/ars.2006.8.2039  0.52
2006 Lovell MA, Markesbery WR. Amyloid beta peptide, 4-hydroxynonenal and apoptosis. Current Alzheimer Research. 3: 359-64. PMID 17017866 DOI: 10.2174/156720506778249506  0.52
2006 Ross GW, Abbott RD, Petrovitch H, Tanner CM, Davis DG, Nelson J, Markesbery WR, Hardman J, Masaki K, Launer L, White LR. Association of olfactory dysfunction with incidental Lewy bodies. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 2062-7. PMID 16991138 DOI: 10.1002/mds.21076  0.52
2006 Forman MS, Mackenzie IR, Cairns NJ, Swanson E, Boyer PJ, Drachman DA, Jhaveri BS, Karlawish JH, Pestronk A, Smith TW, Tu PH, Watts GD, Markesbery WR, Smith CD, Kimonis VE. Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations. Journal of Neuropathology and Experimental Neurology. 65: 571-81. PMID 16783167 DOI: 10.1097/00005072-200606000-00005  0.52
2006 Shao C, Roberts KN, Markesbery WR, Scheff SW, Lovell MA. Oxidative stress in head trauma in aging. Free Radical Biology & Medicine. 41: 77-85. PMID 16781455 DOI: 10.1016/j.freeradbiomed.2006.03.007  0.52
2006 Lovell MA, Smith JL, Markesbery WR. Elevated zinc transporter-6 in mild cognitive impairment, Alzheimer disease, and pick disease. Journal of Neuropathology and Experimental Neurology. 65: 489-98. PMID 16772872 DOI: 10.1097/01.jnen.0000229237.98124.91  0.52
2006 Ding Q, Markesbery WR, Cecarini V, Keller JN. Decreased RNA, and increased RNA oxidation, in ribosomes from early Alzheimer's disease. Neurochemical Research. 31: 705-10. PMID 16770743 DOI: 10.1007/s11064-006-9071-5  0.52
2006 Ding Q, Dimayuga E, Markesbery WR, Keller JN. Proteasome inhibition induces reversible impairments in protein synthesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1055-63. PMID 16770004 DOI: 10.1096/fj.05-5495com  0.52
2006 Anantharaman M, Tangpong J, Keller JN, Murphy MP, Markesbery WR, Kiningham KK, St Clair DK. Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. The American Journal of Pathology. 168: 1608-18. PMID 16651627 DOI: 10.2353/ajpath.2006.051223  0.52
2006 Espinosa PS, Kryscio RJ, Mendiondo MS, Schmitt FA, Wekstein DR, Markesbery WR, Smith CD. Alzheimer's disease and head circumference. Journal of Alzheimer's Disease : Jad. 9: 77-80. PMID 16627937  0.52
2006 Smith JL, Xiong S, Markesbery WR, Lovell MA. Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. Neuroscience. 140: 879-88. PMID 16580781 DOI: 10.1016/j.neuroscience.2006.02.049  0.52
2006 Kryscio RJ, Schmitt FA, Salazar JC, Mendiondo MS, Markesbery WR. Risk factors for transitions from normal to mild cognitive impairment and dementia. Neurology. 66: 828-32. PMID 16567698 DOI: 10.1212/01.wnl.0000203264.71880.45  0.52
2006 Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease. Journal of Neurochemistry. 96: 1322-35. PMID 16478525 DOI: 10.1111/j.1471-4159.2005.03647.x  0.52
2006 Butterfield DA, Poon HF, St Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR. Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease. Neurobiology of Disease. 22: 223-32. PMID 16466929 DOI: 10.1016/j.nbd.2005.11.002  0.52
2006 Wang J, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. Journal of Neurochemistry. 96: 825-32. PMID 16405502 DOI: 10.1111/j.1471-4159.2005.03615.x  0.52
2006 Markesbery WR, Schmitt FA, Kryscio RJ, Davis DG, Smith CD, Wekstein DR. Neuropathologic substrate of mild cognitive impairment. Archives of Neurology. 63: 38-46. PMID 16401735 DOI: 10.1001/archneur.63.1.38  0.52
2006 Sultana R, Poon HF, Cai J, Pierce WM, Merchant M, Klein JB, Markesbery WR, Butterfield DA. Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiology of Disease. 22: 76-87. PMID 16378731 DOI: 10.1016/j.nbd.2005.10.004  0.52
2006 Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Merchant M, Markesbery WR, Butterfield DA. Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiology of Aging. 27: 1564-76. PMID 16271804 DOI: 10.1016/j.neurobiolaging.2005.09.021  0.52
2006 Smith CD, Wekstein DR, Markesbery WR, Frye CA. 3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia. Psychopharmacology. 186: 481-5. PMID 16231167 DOI: 10.1007/s00213-005-0186-1  0.52
2006 Williams TI, Lynn BC, Markesbery WR, Lovell MA. Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiology of Aging. 27: 1094-9. PMID 15993986 DOI: 10.1016/j.neurobiolaging.2005.06.004  0.52
2006 Lovell MA, Geiger H, Van Zant GE, Lynn BC, Markesbery WR. Isolation of neural precursor cells from Alzheimer's disease and aged control postmortem brain. Neurobiology of Aging. 27: 909-17. PMID 15979211 DOI: 10.1016/j.neurobiolaging.2005.05.004  0.52
2006 Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Markesbery WR, Zhou XZ, Lu KP, Butterfield DA. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis. Neurobiology of Aging. 27: 918-25. PMID 15950321 DOI: 10.1016/j.neurobiolaging.2005.05.005  0.52
2006 Bing G, Nguyen XV, Liu M, Markesbery WR, Sun A. Biophysical and biochemical characterization of the intrinsic fluorescence from neurofibrillary tangles. Neurobiology of Aging. 27: 823-30. PMID 15946772 DOI: 10.1016/j.neurobiolaging.2005.04.005  0.52
2006 Martin P, Da Rosa G, Siegler IC, Davey A, MacDonald M, Poon LW, Jazwinski SM, Green RC, Gearing M, Markesbery WR, Woodard JL, Johnson MA, Tenover JS, Rodgers WL, Hausman DB, et al. Personality and longevity: Findings from the Georgia centenarian study Age. 28: 343-352. DOI: 10.1007/s11357-006-9022-8  0.52
2006 Johnson MA, Davey A, Hausman DB, Park S, Poon LW, Jazwinski SM, Green RC, Gearing M, Markesbery WR, Woodard JL, Tenover JS, Siegler IC, Martin P, MacDonald M, Rott C, et al. Dietary differences between centenarians residing in communities and in skilled nursing facilities: The Georgia centenarian study Age. 28: 333-341. DOI: 10.1007/s11357-006-9021-9  0.52
2006 Caban-Holt AM, Schmitt FA, Runyons CR, Kryscio RJ, Mendiondo MS, Healey MS, Markesbery WR, Coltman CA, Crowley JJ, Goodman PJ, Hartline JL. Studying the effects of vitamin E and selenium for Alzheimer's disease prevention: The preadvise model Research and Practice in Alzheimer's Disease. 11: 124-130.  0.52
2005 Markesbery WR, Kryscio RJ, Lovell MA, Morrow JD. Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment. Annals of Neurology. 58: 730-5. PMID 16240347 DOI: 10.1002/ana.20629  0.52
2005 Ding Q, Markesbery WR, Chen Q, Li F, Keller JN. Ribosome dysfunction is an early event in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9171-5. PMID 16207876 DOI: 10.1523/JNEUROSCI.3040-05.2005  0.52
2005 Lovell MA, Smith JL, Xiong S, Markesbery WR. Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. Neurotoxicity Research. 7: 265-71. PMID 16179263 DOI: 10.1007/BF03033884  0.52
2005 Lovell MA, Markesbery WR. Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease. Journal of Neuropathology and Experimental Neurology. 64: 675-80. PMID 16106215  0.52
2005 Wang J, Xiong S, Xie C, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease. Journal of Neurochemistry. 93: 953-62. PMID 15857398 DOI: 10.1111/j.1471-4159.2005.03053.x  0.52
2005 Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfield DA, Markesbery WR. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology. 64: 1152-6. PMID 15824339 DOI: 10.1212/01.WNL.0000156156.13641.BA  0.52
2005 Lovell MA, Xiong S, Markesbery WR, Lynn BC. Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide. Neurochemical Research. 30: 113-22. PMID 15756939 DOI: 10.1007/s11064-004-9692-5  0.52
2005 Montine TJ, Montine KS, McMahan W, Markesbery WR, Quinn JF, Morrow JD. F2-isoprostanes in Alzheimer and other neurodegenerative diseases. Antioxidants & Redox Signaling. 7: 269-75. PMID 15650414 DOI: 10.1089/ars.2005.7.269  0.52
2005 Riley KP, Snowdon DA, Desrosiers MF, Markesbery WR. Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study. Neurobiology of Aging. 26: 341-7. PMID 15639312 DOI: 10.1016/j.neurobiolaging.2004.06.019  0.52
2004 Lovell MA, Xiong S, Xie C, Davies P, Markesbery WR. Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3. Journal of Alzheimer's Disease : Jad. 6: 659-71; discussion 6. PMID 15665406  0.52
2004 Kashon ML, Ross GW, O'Callaghan JP, Miller DB, Petrovitch H, Burchfiel CM, Sharp DS, Markesbery WR, Davis DG, Hardman J, Nelson J, White LR. Associations of cortical astrogliosis with cognitive performance and dementia status. Journal of Alzheimer's Disease : Jad. 6: 595-604; discussion . PMID 15665400  0.52
2004 Ding Q, Dimayuga E, Markesbery WR, Keller JN. Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures. Journal of Neurochemistry. 91: 1211-8. PMID 15569264 DOI: 10.1111/j.1471-4159.2004.02802.x  0.52
2004 Jorm AF, Masaki KH, Davis DG, Hardman J, Nelson J, Markesbery WR, Petrovitch H, Ross GW, White LR. Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease. Neurology. 63: 1960-1. PMID 15557525 DOI: 10.1212/01.WNL.0000144348.70643.F2  0.52
2004 Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, ... Markesbery WR, et al. Genetic and expression profiles of cerebellar liponeurocytomas. Brain Pathology (Zurich, Switzerland). 14: 281-9. PMID 15446583 DOI: 10.1111/j.1750-3639.2004.tb00065.x  0.52
2004 Drake J, Petroze R, Castegna A, Ding Q, Keller JN, Markesbery WR, Lovell MA, Butterfield DA. 4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease. Neuroscience Letters. 356: 155-8. PMID 15036618 DOI: 10.1016/j.neulet.2003.11.047  0.52
2004 Mortimer JA, Gosche KM, Riley KP, Markesbery WR, Snowdon DA. Delayed recall, hippocampal volume and Alzheimer neuropathology: findings from the Nun Study. Neurology. 62: 428-32. PMID 14872025 DOI: 10.1212/01.WNL.0000106463.66966.65  0.52
2004 Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proceedings of the National Academy of Sciences of the United States of America. 101: 2173-8. PMID 14769913 DOI: 10.1073/pnas.0308512100  0.52
2004 Kryscio RJ, Mendiondo MS, Schmitt FA, Markesbery WR. Designing a large prevention trial: statistical issues. Statistics in Medicine. 23: 285-96. PMID 14716729 DOI: 10.1002/sim.1716  0.52
2003 Lovell MA, Xie C, Xiong S, Markesbery WR. Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. Brain Research. 983: 84-96. PMID 12914969 DOI: 10.1016/S0006-8993(03)03032-4  0.52
2003 Lovell MA, Xie C, Xiong S, Markesbery WR. Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid. Journal of Alzheimer's Disease : Jad. 5: 229-39. PMID 12897407  0.52
2003 Mortimer JA, Snowdon DA, Markesbery WR. Head circumference, education and risk of dementia: findings from the Nun Study. Journal of Clinical and Experimental Neuropsychology. 25: 671-9. PMID 12815504 DOI: 10.1076/jcen.25.5.671.14584  0.52
2003 Pulliam JF, Jennings CD, Kryscio RJ, Davis DG, Wilson D, Montine TJ, Schmitt FA, Markesbery WR. Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 119: 48-53. PMID 12707938 DOI: 10.1002/ajmg.b.10069  0.52
2003 Nath A, Hall E, Tuzova M, Dobbs M, Jons M, Anderson C, Woodward J, Guo Z, Fu W, Kryscio R, Wekstein D, Smith C, Markesbery WR, Mattson MP. Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development. Neuromolecular Medicine. 3: 29-39. PMID 12665674 DOI: 10.1385/NMM:3:1:29  0.52
2002 White L, Petrovitch H, Hardman J, Nelson J, Davis DG, Ross GW, Masaki K, Launer L, Markesbery WR. Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants. Annals of the New York Academy of Sciences. 977: 9-23. PMID 12480729  0.52
2002 Castegna A, Aksenov M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. Journal of Neurochemistry. 82: 1524-32. PMID 12354300 DOI: 10.1046/j.1471-4159.2002.01103.x  0.52
2002 Bassett CN, Swift LL, Montine KS, Markesbery WR, Montine TJ. Cerebrospinal fluid lipoprotein delivery to human neuronal cells is increased in Alzheimer's disease and is dependent on apoE monomer concentration. Journal of Alzheimer's Disease : Jad. 4: 19-30. PMID 12214015  0.52
2002 Montine TJ, Neely MD, Quinn JF, Beal MF, Markesbery WR, Roberts LJ, Morrow JD. Lipid peroxidation in aging brain and Alzheimer's disease. Free Radical Biology & Medicine. 33: 620-6. PMID 12208348 DOI: 10.1016/S0891-5849(02)00807-9  0.52
2002 Castegna A, Aksenov M, Aksenova M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radical Biology & Medicine. 33: 562-71. PMID 12160938 DOI: 10.1016/S0891-5849(02)00914-0  0.52
2002 Riley KP, Snowdon DA, Markesbery WR. Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study. Annals of Neurology. 51: 567-77. PMID 12112102 DOI: 10.1002/ana.10161  0.52
2002 Gosche KM, Mortimer JA, Smith CD, Markesbery WR, Snowdon DA. Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study. Neurology. 58: 1476-82. PMID 12034782  0.52
2002 Williamson KS, Gabbita SP, Mou S, West M, Pye QN, Markesbery WR, Cooney RV, Grammas P, Reimann-Philipp U, Floyd RA, Hensley K. The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 6: 221-7. PMID 11890747 DOI: 10.1006/niox.2001.0399  0.52
2002 Lovell MA, Robertson JD, Buchholz BA, Xie C, Markesbery WR. Use of bomb pulse carbon-14 to age senile plaques and neurofibrillary tangles in Alzheimer's disease. Neurobiology of Aging. 23: 179-86. PMID 11804701 DOI: 10.1016/S0197-4580(01)00281-0  0.52
2002 Robertson JD, Crafford AM, Markesbery WR, Lovell MA. Disruption of zinc homeostasis in Alzheimer's disease Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms. 189: 454-458. DOI: 10.1016/S0168-583X(01)01124-7  0.52
2001 Ko LW, Sheu KF, Thaler HT, Markesbery WR, Blass JP. Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability? Journal of Molecular Neuroscience : Mn. 17: 361-9. PMID 11859932 DOI: 10.1385/JMN:17:3:361  0.52
2001 Reich EE, Markesbery WR, Roberts LJ, Swift LL, Morrow JD, Montine TJ. Quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Advances in Experimental Medicine and Biology. 500: 253-6. PMID 11764949  0.52
2001 Schmitt FA, Wetherby MM, Wekstein DR, Dearth CM, Markesbery WR. Brain donation in normal aging: procedures, motivations, and donor characteristics from the Biologically Resilient Adults in Neurological Studies (BRAiNS) Project. The Gerontologist. 41: 716-22. PMID 11723339 DOI: 10.1093/geront/41.6.716  0.52
2001 Gosche KM, Mortimer JA, Smith CD, Markesbery WR, Snowdon DA. An automated technique for measuring hippocampal volumes from MR imaging studies. Ajnr. American Journal of Neuroradiology. 22: 1686-9. PMID 11673162  0.52
2001 Picklo MJ, Olson SJ, Hayes JD, Markesbery WR, Montine TJ. Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease. Brain Research. 916: 229-38. PMID 11597610 DOI: 10.1016/S0006-8993(01)02897-9  0.52
2001 Petrovitch H, White LR, Ross GW, Steinhorn SC, Li CY, Masaki KH, Davis DG, Nelson J, Hardman J, Curb JD, Blanchette PL, Launer LJ, Yano K, Markesbery WR. Accuracy of clinical criteria for AD in the Honolulu-Asia Aging Study, a population-based study. Neurology. 57: 226-34. PMID 11468306 DOI: 10.1212/WNL.57.2.226  0.52
2001 Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42. Journal of Neurochemistry. 78: 413-6. PMID 11461977 DOI: 10.1046/j.1471-4159.2001.00451.x  0.52
2001 Picklo MJ, Olson SJ, Markesbery WR, Montine TJ. Expression and activities of aldo-keto oxidoreductases in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 686-95. PMID 11444797  0.52
2001 Xie C, Lovell MA, Xiong S, Kindy MS, Guo J, Xie J, Amaranth V, Montine TJ, Markesbery WR. Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress. Free Radical Biology & Medicine. 31: 73-81. PMID 11425492 DOI: 10.1016/S0891-5849(01)00553-6  0.52
2001 Wackerbarth SB, Johnson MM, Markesbery WR, Smith CD. Urban-rural differences in a memory disorders clinical population. Journal of the American Geriatrics Society. 49: 647-50. PMID 11380760 DOI: 10.1046/j.1532-5415.2001.49127.x  0.52
2001 Lauderback CM, Hackett JM, Keller JN, Varadarajan S, Szweda L, Kindy M, Markesbery WR, Butterfield DA. Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease. Biochemistry. 40: 2548-54. PMID 11327877 DOI: 10.1021/bi002312k  0.52
2001 Aksenov MY, Markesbery WR. Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neuroscience Letters. 302: 141-5. PMID 11290407 DOI: 10.1016/S0304-3940(01)01636-6  0.52
2001 Lovell MA, Markesbery WR. Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid. Archives of Neurology. 58: 392-6. PMID 11255442  0.52
2001 Aksenov MY, Aksenova MV, Butterfield DA, Geddes JW, Markesbery WR. Protein oxidation in the brain in Alzheimer's disease. Neuroscience. 103: 373-83. PMID 11246152 DOI: 10.1016/S0306-4522(00)00580-7  0.52
2001 Lovell MA, Xie C, Markesbery WR. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiology of Aging. 22: 187-94. PMID 11182468 DOI: 10.1016/S0197-4580(00)00235-9  0.52
2001 Reich EE, Markesbery WR, Roberts LJ, Swift LL, Morrow JD, Montine TJ. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. The American Journal of Pathology. 158: 293-7. PMID 11141503 DOI: 10.1016/S0002-9440(10)63968-5  0.52
2001 Markesbery WR. Use of bomb pulse 14C to age senile plaques and neurofibrillary tangles in the Alzheimer's disease brain Journal of Radioanalytical and Nuclear Chemistry. 249: 443-447. DOI: 10.1023/A:1013299426601  0.52
2000 Lovell MA, Xie C, Markesbery WR. Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. Free Radical Biology & Medicine. 29: 714-20. PMID 11053772 DOI: 10.1016/S0891-5849(00)00346-4  0.52
2000 Rulon LL, Robertson JD, Lovell MA, Deibel MA, Ehmann WD, Markesbery WR. Serum zinc levels and Alzheimer's disease Biological Trace Element Research. 75: 79-85. PMID 11051598  0.52
2000 Schmitt FA, Davis DG, Wekstein DR, Smith CD, Ashford JW, Markesbery WR. "Preclinical" AD revisited: neuropathology of cognitively normal older adults. Neurology. 55: 370-6. PMID 10932270 DOI: 10.1212/WNL.55.3.370  0.52
2000 Keller JN, Markesbery WR. Proteasome inhibition results in increased poly-ADP-ribosylation: implications for neuron death. Journal of Neuroscience Research. 61: 436-42. PMID 10931530 DOI: 10.1002/1097-4547(20000815)61:4<436::AID-JNR10>3.0.CO;2-Z  0.52
2000 Keller JN, Huang FF, Markesbery WR. Decreased levels of proteasome activity and proteasome expression in aging spinal cord. Neuroscience. 98: 149-56. PMID 10858621 DOI: 10.1016/S0306-4522(00)00067-1  0.52
2000 Keller JN, Hanni KB, Markesbery WR. Impaired proteasome function in Alzheimer's disease. Journal of Neurochemistry. 75: 436-9. PMID 10854289 DOI: 10.1046/j.1471-4159.2000.0750436.x  0.52
2000 Aksenov M, Aksenova M, Butterfield DA, Markesbery WR. Oxidative modification of creatine kinase BB in Alzheimer's disease brain. Journal of Neurochemistry. 74: 2520-7. PMID 10820214 DOI: 10.1046/j.1471-4159.2000.0742520.x  0.52
2000 Snowdon DA, Greiner LH, Markesbery WR. Linguistic ability in early life and the neuropathology of Alzheimer's disease and cerebrovascular disease. Findings from the Nun Study. Annals of the New York Academy of Sciences. 903: 34-8. PMID 10818486  0.52
2000 Xie C, Markesbery WR, Lovell MA. Survival of hippocampal and cortical neurons in a mixture of MEM+ and B27-supplemented neurobasal medium. Free Radical Biology & Medicine. 28: 665-72. PMID 10754261 DOI: 10.1016/S0891-5849(99)00268-3  0.52
2000 Keller JN, Lauderback CM, Butterfield DA, Kindy MS, Yu J, Markesbery WR. Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice. Journal of Neurochemistry. 74: 1579-86. PMID 10737615 DOI: 10.1046/j.1471-4159.2000.0741579.x  0.52
2000 Snowdon DA, Tully CL, Smith CD, Riley KP, Markesbery WR. Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study. The American Journal of Clinical Nutrition. 71: 993-8. PMID 10731508  0.52
2000 Keller JN, Hanni KB, Markesbery WR. Possible involvement of proteasome inhibition in aging: implications for oxidative stress. Mechanisms of Ageing and Development. 113: 61-70. PMID 10708250 DOI: 10.1016/S0047-6374(99)00101-3  0.52
2000 Lovell MA, Xie C, Gabbita SP, Markesbery WR. Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain. Free Radical Biology & Medicine. 28: 418-27. PMID 10699754 DOI: 10.1016/S0891-5849(99)00258-0  0.52
2000 Smith CD, Snowdon DA, Wang H, Markesbery WR. White matter volumes and periventricular white matter hyperintensities in aging and dementia. Neurology. 54: 838-42. PMID 10690973  0.52
2000 Smith CD, Snowdon D, Markesbery WR. Periventricular white matter hyperintensities on MRI: correlation with neuropathologic findings. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 10: 13-6. PMID 10666976  0.52
2000 Lovell MA, Xie C, Markesbery WR. Decreased base excision repair and increased helicase activity in Alzheimer's disease brain. Brain Research. 855: 116-23. PMID 10650137 DOI: 10.1016/S0006-8993(99)02335-5  0.52
1999 Bassett CN, Neely MD, Sidell KR, Markesbery WR, Swift LL, Montine TJ. Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo. Lipids. 34: 1273-80. PMID 10652986  0.52
1999 Arnold SM, Young AB, Munn RK, Patchell RA, Nanayakkara N, Markesbery WR. Expression of p53, bcl-2, E-cadherin, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinases-1 in paired primary tumors and brain metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 4028-33. PMID 10632335  0.52
1999 Wolf DS, Gearing M, Snowdon DA, Mori H, Markesbery WR, Mirra SS. Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study. Alzheimer Disease and Associated Disorders. 13: 226-31. PMID 10609672  0.52
1999 Markesbery WR. The role of oxidative stress in Alzheimer disease. Archives of Neurology. 56: 1449-52. PMID 10593298  0.52
1999 Keller JN, Hanni KB, Markesbery WR. 4-hydroxynonenal increases neuronal susceptibility to oxidative stress. Journal of Neuroscience Research. 58: 823-30. PMID 10583913 DOI: 10.1002/(SICI)1097-4547(19991215)58:6<823::AID-JNR9>3.0.CO;2-T  0.52
1999 Montine TJ, Sidell KR, Crews BC, Markesbery WR, Marnett LJ, Roberts LJ, Morrow JD. Elevated CSF prostaglandin E2 levels in patients with probable AD. Neurology. 53: 1495-8. PMID 10534257  0.52
1999 Smith CD, Umberger GH, Manning EL, Slevin JT, Wekstein DR, Schmitt FA, Markesbery WR, Zhang Z, Gerhardt GA, Kryscio RJ, Gash DM. Critical decline in fine motor hand movements in human aging. Neurology. 53: 1458-61. PMID 10534251 DOI: 10.1212/WNL.53.7.1458  0.52
1999 Aksenova MV, Aksenov MY, Markesbery WR, Butterfield DA. Aging in a dish: age-dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long-term hippocampal cell culture. Journal of Neuroscience Research. 58: 308-17. PMID 10502287 DOI: 10.1002/(SICI)1097-4547(19991015)58:2<308::AID-JNR11>3.0.CO;2-#  0.52
1999 Gabbita SP, Aksenov MY, Lovell MA, Markesbery WR. Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain. Journal of Neurochemistry. 73: 1660-6. PMID 10501213 DOI: 10.1046/j.1471-4159.1999.0731660.x  0.52
1999 Montine TJ, Markesbery WR, Zackert W, Sanchez SC, Roberts LJ, Morrow JD. The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients. The American Journal of Pathology. 155: 863-8. PMID 10487843 DOI: 10.1016/S0002-9440(10)65185-1  0.52
1999 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease. Neurochemical Research. 24: 767-74. PMID 10447460 DOI: 10.1023/A:1020783614031  0.52
1999 Keller JN, Hanni KB, Markesbery WR. Oxidized low-density lipoprotein induces neuronal death: implications for calcium, reactive oxygen species, and caspases. Journal of Neurochemistry. 72: 2601-9. PMID 10349872 DOI: 10.1046/j.1471-4159.1999.0722601.x  0.52
1999 Morris DJ, Carroll W, Yaes RJ, Patchell RA, Tibbs PA, Regine WF, Mohiuddin M, Kryscio RJ, Markesbery WR, Foon KA, Young B, Dempsey RJ. Postoperative radiotherapy for single brain metastases [3] (multiple letters) Journal of the American Medical Association. 281: 1695-1696. PMID 10328062 DOI: 10.1001/jama.281.18.1695  0.52
1999 Lanska DJ, Markesbery WR. CADASIL in a North American family. Neurology. 52: 1518-9. PMID 10227656  0.52
1999 Keller JN, Hanni KB, Pedersen WA, Cashman NR, Mattson MP, Gabbita SP, Friebe V, Markesbery WR. Opposing actions of native and oxidized lipoprotein on motor neuron-like cells. Experimental Neurology. 157: 202-10. PMID 10222123 DOI: 10.1006/exnr.1999.7043  0.52
1999 Davis DG, Schmitt FA, Wekstein DR, Markesbery WR. Alzheimer neuropathologic alterations in aged cognitively normal subjects. Journal of Neuropathology and Experimental Neurology. 58: 376-88. PMID 10218633 DOI: 10.1097/00005072-199904000-00008  0.52
1999 Hensley K, Floyd RA, Zheng NY, Nael R, Robinson KA, Nguyen X, Pye QN, Stewart CA, Geddes J, Markesbery WR, Patel E, Johnson GV, Bing G. p38 kinase is activated in the Alzheimer's disease brain. Journal of Neurochemistry. 72: 2053-8. PMID 10217284 DOI: 10.1046/j.1471-4159.1999.0722053.x  0.52
1999 Goedert M, Spillantini MG, Crowther RA, Chen SG, Parchi P, Tabaton M, Lanska DJ, Markesbery WR, Wilhelmsen KC, Dickson DW, Petersen RB, Gambetti P. Tau gene mutation in familial progressive subcortical gliosis. Nature Medicine. 5: 454-7. PMID 10202939 DOI: 10.1038/7454  0.52
1999 Lovell MA, Xie C, Markesbery WR. Protection against amyloid beta peptide toxicity by zinc. Brain Research. 823: 88-95. PMID 10095015 DOI: 10.1016/S0006-8993(99)01114-2  0.52
1999 Saxe SR, Wekstein MW, Kryscio RJ, Henry RG, Cornett CR, Snowdon DA, Grant FT, Schmitt FA, Donegan SJ, Wekstein DR, Ehmann WD, Markesbery WR. Alzheimer's disease, dental amalgam and mercury. Journal of the American Dental Association (1939). 130: 191-9. PMID 10036842 DOI: 10.14219/JADA.ARCHIVE.1999.0168  0.52
1999 Aksenova MV, Aksenov MY, Payne RM, Trojanowski JQ, Schmidt ML, Carney JM, Butterfield DA, Markesbery WR. Oxidation of cytosolic proteins and expression of creatine kinase BB in frontal lobe in different neurodegenerative disorders. Dementia and Geriatric Cognitive Disorders. 10: 158-65. PMID 10026391 DOI: 10.1159/000017098  0.52
1999 Markesbery WR, Carney JM. Oxidative alterations in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 9: 133-46. PMID 9989456  0.52
1999 Lovell MA, Gabbita SP, Markesbery WR. Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF. Journal of Neurochemistry. 72: 771-6. PMID 9930752 DOI: 10.1046/j.1471-4159.1999.0720771.x  0.52
1999 Smith CD, Malcein M, Meurer K, Schmitt FA, Markesbery WR, Pettigrew LC. MRI temporal lobe volume measures and neuropsychologic function in Alzheimer's disease. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 9: 2-9. PMID 9922716  0.52
1998 Yatin SM, Aksenova M, Aksenov M, Markesbery WR, Aulick T, Butterfield DA. Temporal relations among amyloid beta-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses. Journal of Molecular Neuroscience : Mn. 11: 183-97. PMID 10344789 DOI: 10.1385/JMN:11:3:183  0.52
1998 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 11: 151-64. PMID 10096042 DOI: 10.1385/JMN:11:2:151  0.52
1998 Keller JN, Hanni KB, Mattson MP, Markesbery WR. Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity. Neuroreport. 9: 3731-4. PMID 9858387 DOI: 10.1097/00001756-199811160-00029  0.52
1998 Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease. Neurology. 51: 1562-6. PMID 9855502  0.52
1998 Xie C, Lovell MA, Markesbery WR. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radical Biology & Medicine. 25: 979-88. PMID 9840744 DOI: 10.1016/S0891-5849(98)00186-5  0.52
1998 Montine KS, Bassett CN, Ou JJ, Markesbery WR, Swift LL, Montine TJ. Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins. Journal of Lipid Research. 39: 2443-51. PMID 9831633  0.52
1998 Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ, Markesbery WR, Foon KA, Young B. Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. Jama. 280: 1485-9. PMID 9809728 DOI: 10.1001/jama.280.17.1485  0.52
1998 Zhang D, Dhillon H, Prasad MR, Markesbery WR. Regional levels of brain phospholipase Cgamma in Alzheimer's disease. Brain Research. 811: 161-5. PMID 9804940 DOI: 10.1016/S0006-8993(98)00935-4  0.52
1998 Gabbita SP, Lovell MA, Markesbery WR. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. Journal of Neurochemistry. 71: 2034-40. PMID 9798928  0.52
1998 Montine TJ, Markesbery WR, Morrow JD, Roberts LJ. Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease. Annals of Neurology. 44: 410-3. PMID 9749613 DOI: 10.1002/ana.410440322  0.32
1998 Lovell MA, Robertson JD, Teesdale WJ, Campbell JL, Markesbery WR. Copper, iron and zinc in Alzheimer's disease senile plaques. Journal of the Neurological Sciences. 158: 47-52. PMID 9667777 DOI: 10.1016/S0022-510X(98)00092-6  0.32
1998 Lanska DJ, Markesbery WR, Cochran E, Bennett D, Lanska MJ, Cohen M. Late-onset sporadic progressive subcortical gliosis. Journal of the Neurological Sciences. 157: 143-7. PMID 9619636 DOI: 10.1016/S0022-510X(98)00063-X  0.52
1998 Bruce-Keller AJ, Li YJ, Lovell MA, Kraemer PJ, Gary DS, Brown RR, Markesbery WR, Mattson MP. 4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats. Journal of Neuropathology and Experimental Neurology. 57: 257-67. PMID 9600218 DOI: 10.1097/00005072-199803000-00007  0.32
1998 Challa VR, Lovell MA, Moody DM, Brown WR, Reboussin DM, Markesbery WR. Laser microprobe mass spectrometric study of aluminum and silicon in brain emboli related to cardiac surgery. Journal of Neuropathology and Experimental Neurology. 57: 140-7. PMID 9600206  0.32
1998 Tekirian TL, Saido TC, Markesbery WR, Russell MJ, Wekstein DR, Patel E, Geddes JW. N-terminal heterogeneity of parenchymal and cerebrovascular Abeta deposits. Journal of Neuropathology and Experimental Neurology. 57: 76-94. PMID 9600199 DOI: 10.1097/00005072-199801000-00009  0.44
1998 Montine KS, Reich E, Neely MD, Sidell KR, Olson SJ, Markesbery WR, Montine TJ. Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype. Journal of Neuropathology and Experimental Neurology. 57: 415-25. PMID 9596412  0.32
1998 Roberts LJ, Montine TJ, Markesbery WR, Tapper AR, Hardy P, Chemtob S, Dettbarn WD, Morrow JD. Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid. The Journal of Biological Chemistry. 273: 13605-12. PMID 9593698 DOI: 10.1074/jbc.273.22.13605  0.32
1998 Markesbery WR, Lovell MA. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiology of Aging. 19: 33-6. PMID 9562500 DOI: 10.1016/S0197-4580(98)00009-8  0.32
1998 Pettigrew LC, Bieber F, Lettieri J, Wermeling DP, Schmitt FA, Tikhtman AJ, Ashford JW, Smith CD, Wekstein DR, Markesbery WR, Orazem J, Ruzicka BB, Mas J, Gulanski B. Pharmacokinetics, pharmacodynamics, and safety of metrifonate in patients with Alzheimer's disease. Journal of Clinical Pharmacology. 38: 236-45. PMID 9549662 DOI: 10.1002/j.1552-4604.1998.tb04421.x  0.48
1998 Prasad MR, Lovell MA, Yatin M, Dhillon H, Markesbery WR. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochemical Research. 23: 81-8. PMID 9482271 DOI: 10.1023/A:1022457605436  0.32
1997 Lovell MA, Ehmann WD, Mattson MP, Markesbery WR. Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiology of Aging. 18: 457-61. PMID 9390770 DOI: 10.1016/S0197-4580(97)00108-5  0.32
1997 Geddes JW, Tekirian TL, Soultanian NS, Ashford JW, Davis DG, Markesbery WR. Comparison of neuropathologic criteria for the diagnosis of Alzheimer's disease. Neurobiology of Aging. 18: S99-105. PMID 9330997  0.44
1997 Aksenov MY, Aksenova MV, Payne RM, Smith CD, Markesbery WR, Carney JM. The expression of creatine kinase isoenzymes in neocortex of patients with neurodegenerative disorders: Alzheimer's and Pick's disease. Experimental Neurology. 146: 458-65. PMID 9270056 DOI: 10.1006/exnr.1997.6550  0.48
1997 Montine KS, Kim PJ, Olson SJ, Markesbery WR, Montine TJ. 4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease. Journal of Neuropathology and Experimental Neurology. 56: 866-71. PMID 9258256 DOI: 10.1097/00005072-199708000-00004  0.32
1997 Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. Journal of Neurochemistry. 68: 255-64. PMID 8978733  0.32
1996 Lovell MA, Ehmann WD, Markesbery WR, Melethil S, Swyt CR, Zatta PF. Standardization in biological analyses of aluminum: what are the needs? Journal of Toxicology and Environmental Health. 48: 637-48. PMID 8772803  0.32
1996 Tekirian TL, Cole GM, Russell MJ, Yang F, Wekstein DR, Patel E, Snowdon DA, Markesbery WR, Geddes JW. Carboxy terminal of beta-amyloid deposits in aged human, canine, and polar bear brains. Neurobiology of Aging. 17: 249-57. PMID 8744406  0.44
1995 Petersen RB, Tabaton M, Chen SG, Monari L, Richardson SL, Lynch T, Manetto V, Lanska DJ, Markesbery WR, Lynches T [corrected to Lynch T]. Familial progressive subcortical gliosis: presence of prions and linkage to chromosome 17. Neurology. 45: 1062-7. PMID 7783864 DOI: 10.1212/WNL.45.6.1062  0.52
1995 Lovell MA, Ehmann WD, Butler SM, Markesbery WR. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology. 45: 1594-601. PMID 7644059  0.32
1995 Mattson MP, Lovell MA, Furukawa K, Markesbery WR. Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. Journal of Neurochemistry. 65: 1740-51. PMID 7561872  0.32
1993 Smith CD, Gallenstein LG, Layton WJ, Kryscio RJ, Markesbery WR. 31P magnetic resonance spectroscopy in Alzheimer's and Pick's disease. Neurobiology of Aging. 14: 85-92. PMID 8450937 DOI: 10.1016/0197-4580(93)90026-8  0.48
1993 Mattson MP, Lovell MA, Ehmann WD, Markesbery WR. Comparison of the effects of elevated intracellular aluminum and calcium levels on neuronal survival and tau immunoreactivity. Brain Research. 602: 21-31. PMID 8448655 DOI: 10.1016/0006-8993(93)90236-G  0.32
1993 Markesbery WR, Wang HZ, Kowall NW, Kosik KS, McKee AC. Morphometric image analysis of neuropil threads in Alzheimer's disease. Neurobiology of Aging. 14: 303-7. PMID 8367011 DOI: 10.1016/0197-4580(93)90115-R  0.52
1993 Hamill RW, Markesbery WR, McDaniel K, Coleman PD. Characterization of brain samples in studies of aging, Alzheimer's, and other neurodegenerative diseases. Neurobiology of Aging. 14: 539-45. PMID 8295656 DOI: 10.1016/0197-4580(93)90037-C  0.52
1993 Lovell MA, Ehmann WD, Markesbery WR. Laser microprobe analysis of brain aluminum in Alzheimer's disease. Annals of Neurology. 33: 36-42. PMID 8257483 DOI: 10.1002/ana.410330107  0.32
1993 Davis DG, Wilson D, Schmitz M, Markesbery WR. Lipidized medulloblastoma in adults. Human Pathology. 24: 990-5. PMID 8068063 DOI: 10.1016/0046-8177(93)90113-U  0.44
1992 Davis DG, Markesbery WR. Perivascular siderophages in skeletal muscle from a patient with diabetic neuropathy. Acta Neuropathologica. 84: 216-20. PMID 1523977 DOI: 10.1007/BF00311399  0.44
1992 Russell MJ, White R, Patel E, Markesbery WR, Watson CR, Geddes JW. Familial influence on plaque formation in the beagle brain. Neuroreport. 3: 1093-6. PMID 1493222  0.44
1992 Smith CD, Carney JM, Tatsumo T, Stadtman ER, Floyd RA, Markesbery WR. Protein oxidation in aging brain. Annals of the New York Academy of Sciences. 663: 110-9. PMID 1362341 DOI: 10.1111/j.1749-6632.1992.tb38654.x  0.52
1992 DeKosky ST, Harbaugh RE, Schmitt FA, Bakay RA, Chui HC, Knopman DS, Reeder TM, Shetter AG, Senter HJ, Markesbery WR. Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group. Annals of Neurology. 32: 625-32. PMID 1360195 DOI: 10.1002/ana.410320505  0.48
1992 Sparks DL, Hunsaker JC, Slevin JT, DeKosky ST, Kryscio RJ, Markesbery WR. Monoaminergic and cholinergic synaptic markers in the nucleus basalis of Meynert (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease. Annals of Neurology. 31: 611-20. PMID 1355334 DOI: 10.1002/ana.410310608  0.48
1992 Davis DG, Wang HZ, Markesbery WR. Image analysis of neuropil threads in Alzheimer's, Pick's, diffuse Lewy body disease and in progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. 51: 594-600. PMID 1336541  0.44
1991 Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, Markesbery WR. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 88: 10540-3. PMID 1683703 DOI: 10.1073/pnas.88.23.10540  0.52
1990 Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B. A randomized trial of surgery in the treatment of single metastases to the brain. The New England Journal of Medicine. 322: 494-500. PMID 2405271 DOI: 10.1056/NEJM199002223220802  0.48
1990 Davis DG, Nelson KR, Markesbery WR. Congenital myopathy and cardiomyopathy with identical ultrastructural changes. Archives of Neurology. 47: 1141-4. PMID 2222249 DOI: 10.1001/archneur.1990.00530100111026  0.44
1990 Smith CD, Thomas GS, Kryscio RJ, Markesbery WR. 31P spectroscopy in experimental embolic stroke: correlation with infarct size. Nmr in Biomedicine. 3: 259-64. PMID 2092741  0.48
1990 Sparks DL, Hunsaker JC, Scheff SW, Kryscio RJ, Henson JL, Markesbery WR. Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease. Neurobiology of Aging. 11: 601-7. PMID 1704106 DOI: 10.1016/0197-4580(90)90024-T  0.48
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