Kristine Wiren - Publications

Affiliations: 
Behavioral Neuroscience Oregon Health and Science University, Portland, OR 
Area:
androgen receptor, androgen, estrogen, alcohol abuse, alcohol withdrawal, neurotoxicity, osteoporosis
Website:
http://www.ohsu.edu/xd/education/schools/school-of-medicine/departments/basic-science-departments/behn/people/wiren.cfm

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Hashimoto JG, Gavin DP, Wiren KM, Crabbe JC, Guizzetti M. Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence. Alcohol (Fayetteville, N.Y.). PMID 28433423 DOI: 10.1016/j.alcohol.2017.01.010  0.44
2016 Hashimoto J, Wiren KM, Wilhelm CJ. A neurotoxic alcohol exposure paradigm does not induce hepatic encephalopathy. Neurotoxicology and Teratology. PMID 27268733 DOI: 10.1016/j.ntt.2016.06.001  1
2015 Wilhelm CJ, Hashimoto JG, Roberts ML, Bloom SH, Andrew MR, Wiren KM. Astrocyte Dysfunction Induced by Alcohol in Females but Not Males. Brain Pathology (Zurich, Switzerland). PMID 26088166 DOI: 10.1111/bpa.12276  1
2015 Wilhelm CJ, Hashimoto JG, Roberts ML, Bloom SH, Beard DK, Wiren KM. Females uniquely vulnerable to alcohol-induced neurotoxicity show altered glucocorticoid signaling. Brain Research. 1601: 102-16. PMID 25601008 DOI: 10.1016/j.brainres.2015.01.002  1
2015 Russell PK, Clarke MV, Cheong K, Anderson PH, Morris HA, Wiren KM, Zajac JD, Davey RA. Androgen receptor action in osteoblasts in male mice is dependent on their stage of maturation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 809-23. PMID 25407961 DOI: 10.1002/jbmr.2413  1
2014 Wilhelm CJ, Hashimoto JG, Roberts ML, Sonmez MK, Wiren KM. Understanding the addiction cycle: a complex biology with distinct contributions of genotype vs. sex at each stage. Neuroscience. 279: 168-86. PMID 25194791 DOI: 10.1016/j.neuroscience.2014.08.041  1
2014 Cozzoli DK, Strong-Kaufman MN, Tanchuck MA, Hashimoto JG, Wiren KM, Finn DA. The effect of mGluR5 antagonism during binge drinking on subsequent ethanol intake in C57BL/6J mice: Sex- and age-induced differences Alcoholism: Clinical and Experimental Research. 38: 730-738. DOI: 10.1111/acer.12292  1
2013 Wiren KM. Males and females are just different: sexually dimorphic responses to chronic ethanol exposure in hippocampal slice cultures. Neuroscience Letters. 550: 1-5. PMID 23819983 DOI: 10.1016/j.neulet.2013.06.030  1
2013 Wiren KM. Androgens and Skeletal Biology: Basic Mechanisms Osteoporosis: Fourth Edition. 345-371. DOI: 10.1016/B978-0-12-415853-5.00015-7  1
2012 Wiren KM, Zhang XW, Olson DA, Turner RT, Iwaniec UT. Androgen prevents hypogonadal bone loss via inhibition of resorption mediated by mature osteoblasts/osteocytes. Bone. 51: 835-46. PMID 22910580 DOI: 10.1016/j.bone.2012.08.111  1
2011 Ayala P, Uchida M, Akiyoshi K, Cheng J, Hashimoto J, Jia T, Ronnekleiv OK, Murphy SJ, Wiren KM, Hurn PD. Androgen receptor overexpression is neuroprotective in experimental stroke. Translational Stroke Research. 2: 346-57. PMID 24323653 DOI: 10.1007/s12975-011-0079-z  1
2011 Wiren KM, Hashimoto JG, Zhang XW. Stem cell activation in adults can reverse detrimental changes in body composition to reduce fat and increase lean mass in both sexes. Journal of Cellular Biochemistry. 112: 3638-47. PMID 21793043 DOI: 10.1002/jcb.23288  1
2011 Wiren KM, Hashimoto JG, Semirale AA, Zhang XW. Bone vs. fat: embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts. Bone. 49: 662-72. PMID 21704206 DOI: 10.1016/j.bone.2011.06.010  1
2011 Semirale AA, Zhang XW, Wiren KM. Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation. Journal of Cellular Biochemistry. 112: 1773-86. PMID 21381083 DOI: 10.1002/jcb.23098  1
2011 Lebold KM, Grant KA, Freeman WM, Wiren KM, Miller GW, Kiley C, Leonard SW, Traber MG. Individual differences in hyperlipidemia and vitamin E status in response to chronic alcohol self-administration in cynomolgus monkeys. Alcoholism, Clinical and Experimental Research. 35: 474-83. PMID 21118275 DOI: 10.1111/j.1530-0277.2010.01364.x  1
2011 Hashimoto JG, Forquer MR, Tanchuck MA, Finn DA, Wiren KM. Importance of genetic background for risk of relapse shown in altered prefrontal cortex gene expression during abstinence following chronic alcohol intoxication. Neuroscience. 173: 57-75. PMID 21081154 DOI: 10.1016/j.neuroscience.2010.11.006  1
2011 Forquer MR, Hashimoto JG, Roberts ML, Wiren KM. Elevated testosterone in females reveals a robust sex difference in altered androgen levels during chronic alcohol withdrawal. Alcohol (Fayetteville, N.Y.). 45: 161-71. PMID 20843636 DOI: 10.1016/j.alcohol.2010.08.013  1
2010 Wiren KM, Semirale AA, Hashimoto JG, Zhang XW. Signaling pathways implicated in androgen regulation of endocortical bone. Bone. 46: 710-23. PMID 19895913 DOI: 10.1016/j.bone.2009.10.039  1
2010 Wiren KM, Orwoll ES. Androgens and Bone: Basic Aspects Osteoporosis in Men. 295-317. DOI: 10.1016/B978-0-12-374602-3.00025-0  1
2009 Tanchuck MA, Long SL, Ford MM, Hashimoto J, Crabbe JC, Roselli CE, Wiren KM, Finn DA. Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression. Alcoholism, Clinical and Experimental Research. 33: 2077-87. PMID 19740134 DOI: 10.1111/j.1530-0277.2009.01047.x  1
2009 Wheeler JM, Reed C, Burkhart-Kasch S, Li N, Cunningham CL, Janowsky A, Franken FH, Wiren KM, Hashimoto JG, Scibelli AC, Phillips TJ. Genetically correlated effects of selective breeding for high and low methamphetamine consumption. Genes, Brain, and Behavior. 8: 758-71. PMID 19689456 DOI: 10.1111/j.1601-183X.2009.00522.x  1
2008 Wiren KM, Semirale AA, Zhang XW, Woo A, Tommasini SM, Price C, Schaffler MB, Jepsen KJ. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton. Bone. 43: 440-51. PMID 18595795 DOI: 10.1016/j.bone.2008.04.026  1
2008 Hashimoto JG, Wiren KM. Neurotoxic consequences of chronic alcohol withdrawal: expression profiling reveals importance of gender over withdrawal severity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1084-96. PMID 17593928 DOI: 10.1038/sj.npp.1301494  1
2008 Wiren KM. Androgens Receptor Expression and Steroid Action in Bone Principles of Bone Biology, Two-Volume Set. 2: 1001-1023. DOI: 10.1016/B978-0-12-373884-4.00062-8  1
2007 Gorin-Meyer RE, Wiren KM, Tanchuck MA, Long SL, Yoneyama N, Finn DA. Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice. Neuroscience. 146: 1302-15. PMID 17428611 DOI: 10.1016/j.neuroscience.2007.02.051  1
2006 Beadles-Bohling AS, Wiren KM. Anticonvulsive effects of kappa-opioid receptor modulation in an animal model of ethanol withdrawal. Genes, Brain, and Behavior. 5: 483-96. PMID 16923153 DOI: 10.1111/j.1601-183X.2005.00200.x  1
2006 Bliziotes M, Eshleman A, Burt-Pichat B, Zhang XW, Hashimoto J, Wiren K, Chenu C. Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells Bone. 39: 1313-1321. PMID 16884969 DOI: 10.1016/j.bone.2006.06.009  1
2006 Finn DA, Beadles-Bohling AS, Beckley EH, Ford MM, Gililland KR, Gorin-Meyer RE, Wiren KM. A new look at the 5alpha-reductase inhibitor finasteride. Cns Drug Reviews. 12: 53-76. PMID 16834758 DOI: 10.1111/j.1527-3458.2006.00053.x  1
2006 Wiren KM, Hashimoto JG, Alele PE, Devaud LL, Price KL, Middaugh LD, Grant KA, Finn DA. Impact of sex: determination of alcohol neuroadaptation and reinforcement. Alcoholism, Clinical and Experimental Research. 30: 233-42. PMID 16441272 DOI: 10.1111/j.1530-0277.2006.00032.x  1
2006 Wiren KM, Toombs AR, Semirale AA, Zhang X. Osteoblast and osteocyte apoptosis associated with androgen action in bone: requirement of increased Bax/Bcl-2 ratio. Bone. 38: 637-51. PMID 16413235 DOI: 10.1016/j.bone.2005.10.029  1
2005 Wiren KM. Androgens and bone growth: it's location, location, location. Current Opinion in Pharmacology. 5: 626-32. PMID 16185926 DOI: 10.1016/j.coph.2005.06.003  1
2005 Warden SJ, Bliziotes MM, Wiren KM, Eshleman AJ, Turner CH. Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine). Molecular and Cellular Endocrinology. 242: 1-9. PMID 16085354 DOI: 10.1016/j.mce.2005.06.005  1
2005 Beadles-Bohling AS, Wiren KM. Alteration of kappa-opioid receptor system expression in distinct brain regions of a genetic model of enhanced ethanol withdrawal severity. Brain Research. 1046: 77-89. PMID 15869750 DOI: 10.1016/j.brainres.2005.03.043  1
2005 McBride WJ, Kerns RT, Rodd ZA, Strother WN, Edenberg HJ, Hashimoto JG, Wiren KM, Miles MF. Alcohol effects on central nervous system gene expression in genetic animal models. Alcoholism, Clinical and Experimental Research. 29: 167-75. PMID 15714040 DOI: 10.1097/01.ALC.0000153539.40955.42  1
2004 Wiren KM, Zhang XW, Toombs AR, Kasparcova V, Gentile MA, Harada S, Jepsen KJ. Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals. Endocrinology. 145: 3507-22. PMID 15131013 DOI: 10.1210/en.2003-1016  1
2004 Wiren KM, Toombs AR, Zhang XW. Androgen inhibition of MAP kinase pathway and Elk-1 activation in proliferating osteoblasts Journal of Molecular Endocrinology. 32: 209-226. PMID 14766003 DOI: 10.1677/jme.0.0320209  1
2004 Finn DA, Ford MM, Wiren KM, Roselli CE, Crabbe JC. The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches. Pharmacology & Therapeutics. 101: 91-112. PMID 14761701 DOI: 10.1016/j.pharmthera.2003.10.006  1
2004 Hashimoto JG, Beadles-Bohling AS, Wiren KM. Comparison of RiboGreen and 18S rRNA quantitation for normalizing real-time RT-PCR expression analysis. Biotechniques. 36: 54-6, 58-60. PMID 14740484  1
2002 Wiren KM, Evans AC, Zhang XW. Osteoblast differentiation influences androgen and estrogen receptor-α and -β expression Journal of Endocrinology. 175: 683-694. PMID 12475379 DOI: 10.1677/joe.0.1750683  1
2002 Bliziotes M, Gunness M, Eshleman A, Wiren K. The role of dopamine and serotonin in regulating bone mass and strength: Studies on dopamine and serotonin transporter null mice Journal of Musculoskeletal Neuronal Interactions. 2: 291-295.  1
2001 Bliziotes MM, Eshleman AJ, Zhang XW, Wiren KM. Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone. 29: 477-86. PMID 11704501 DOI: 10.1016/S8756-3282(01)00593-2  1
2001 Schafer GL, Crabbe JC, Wiren KM. Ethanol-regulated gene expression of neuroendocrine specific protein in mice: brain region and genotype specificity. Brain Research. 897: 139-49. PMID 11282367 DOI: 10.1016/S0006-8993(01)02110-2  1
2001 Billiard J, Umayahara Y, Wiren K, Centrella M, McCarthy TL, Rotwein P. Regulated Nuclear-Cytoplasmic Localization of CCAAT/Enhancer-binding Protein δ in Osteoblasts Journal of Biological Chemistry. 276: 15354-15361. PMID 11278589 DOI: 10.1074/jbc.M009973200  1
2000 Bliziotes M, Gunness M, Zhang XW, Nissenson R, Wiren K. Reduced G-protein-coupled-receptor kinase 2 activity results in impairment of osteoblast function Bone. 27: 367-373. PMID 10962347 DOI: 10.1016/S8756-3282(00)00338-0  1
2000 Beadles-Bohling AS, Crabbe JC, Wiren KM. Elevated prodynorphin expression associated with ethanol withdrawal convulsions. Neurochemistry International. 37: 463-72. PMID 10871698 DOI: 10.1016/S0197-0186(00)00056-5  1
1999 Wiren K, Keenan E, Zhang X, Ramsey B, Orwoll E. Homologous androgen receptor up-regulation in osteoblastic cells may be associated with enhanced functional androgen responsiveness. Endocrinology. 140: 3114-24. PMID 10385404 DOI: 10.1210/endo.140.7.6753  1
1998 Schafer GL, Crabbe JC, Wiren KM. Identification of neuroendocrine-specific protein as an ethanol-regulated gene with mRNA differential display. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 979-82. PMID 9880663 DOI: 10.1007/s003359900910  1
1997 Wiren KM, Zhang X, Chang C, Keenan E, Orwoll ES. Transcriptional up-regulation of the human androgen receptor by androgen in bone cells. Endocrinology. 138: 2291-300. PMID 9165014 DOI: 10.1210/endo.138.6.5163  1
1996 Bliziotes M, Murtagh J, Wiren K. β-Adrenergic receptor kinase-like activity and β-arrestin are expressed in osteoblastic cells Journal of Bone and Mineral Research. 11: 820-826. PMID 8725179  1
1995 Birnbaum RS, Bowsher RR, Wiren KM. Changes in IGF-I and -II expression and secretion during the proliferation and differentiation of normal rat osteoblasts Journal of Endocrinology. 144: 251-259. PMID 7535835  1
1994 Birnbaum RS, Wiren KM. Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts Endocrinology. 135: 223-230. PMID 8013356 DOI: 10.1210/en.135.1.223  1
1993 Klein RF, Wiren KM. Regulation of osteoblastic gene expression by lead Endocrinology. 132: 2531-2537. PMID 8504755  1
1992 Baba H, Karaplis AC, Wiren KM, Keutmann HT, Kronenberg HM. Interaction of nascent preproparathyroid hormone molecules with microsomal membranes Journal of Bone and Mineral Research. 7: 199-206. PMID 1570764  1
1992 Kuijper JL, Wiren KM, Mathies LD, Gray CL, Hagen FS. Functional cloning vectors for use in directional cDNA cloning using cohesive ends produced with T4 DNA polymerase Gene. 112: 147-155. PMID 1532564 DOI: 10.1016/0378-1119(92)90370-5  1
1991 Plymate SR, Loop SM, Hoop RC, Wiren KM, Ostenson R, Hryb DJ, Rosner W. Effects of sex hormone binding globulin (SHBG) on human prostatic carcinoma Journal of Steroid Biochemistry and Molecular Biology. 40: 833-839. PMID 1958578 DOI: 10.1016/0960-0760(91)90309-S  1
1989 Wiren KM, Ivashkiv L, Ma P, Freeman MW, Potts JT, Kronenberg HM. Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties Molecular Endocrinology. 3: 240-250. PMID 2710131  1
1988 Wiren KM, Potts JT, Kronenberg HM. Importance of the propeptide sequence of human preproparathyroid hormone for signal sequence function Journal of Biological Chemistry. 263: 19771-19777. PMID 3198649  1
1987 Wiren KM, Freeman MW, Potts JT, Kronenberg HM. Preproparathyroid hormone. A model for analyzing the secretory pathway Annals of the New York Academy of Sciences. 493: 43-49. PMID 3473968  1
1987 Freeman MW, Wiren KM, Rapoport A, Lazar M, Potts JT, Kronenberg HM. Consequences of amino-terminal deletions of preproparathyroid hormone signal sequence Molecular Endocrinology (Baltimore, Md.). 1: 628-638. PMID 3153480  1
1986 Kronenberg HM, Igarashi T, Freeman MW, Okazaki T, Brand SJ, Wiren KM, Potts JT. Structure and expression of the human parathyroid hormone gene Recent Progress in Hormone Research. 42: 641-663. PMID 3526456  1
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