Stephen J. Tucker - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Ion Channel Biophysics

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Klesse G, Tucker SJ, Sansom MSP. Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT Receptor Channel. Acs Nano. PMID 32673478 DOI: 10.1021/acsnano.0c04387  1
2020 Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, ... ... Tucker SJ, et al. A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature. PMID 32499642 DOI: 10.1038/s41586-020-2250-8  1
2020 Imbrici P, Nematian-Ardestani E, Hasan S, Pessia M, Tucker SJ, D'Adamo MC. Altered functional properties of a missense variant in the TRESK K channel (KCNK18) associated with migraine and intellectual disability. Pflugers Archiv : European Journal of Physiology. PMID 32394190 DOI: 10.1007/s00424-020-02382-5  1
2020 Klesse G, Rao S, Tucker SJ, Sansom MSP. Induced Polarization in MD Simulations of the 5HT3 Receptor Channel. Journal of the American Chemical Society. PMID 32336093 DOI: 10.1021/jacs.0c02394  1
2020 Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins. Nature Structural & Molecular Biology. PMID 32066965 DOI: 10.1038/s41594-020-0396-6  1
2020 Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. Structure and assembly of calcium homeostasis modulator proteins. Nature Structural & Molecular Biology. PMID 31988524 DOI: 10.1038/s41594-019-0369-9  1
2019 Nematian-Ardestani E, Abd-Wahab MF, Chatelain FC, Sun H, Schewe M, Baukrowitz T, Tucker SJ. Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ Channel. The Journal of Biological Chemistry. PMID 31806709 DOI: 10.1074/jbc.RA119.010612  1
2019 Rao S, Klesse G, Stansfeld PJ, Tucker SJ, Sansom MSP. A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates. Proceedings of the National Academy of Sciences of the United States of America. PMID 31235590 DOI: 10.1073/pnas.1902702116  1
2019 Klesse G, Rao S, Sansom MSP, Tucker SJ. CHAP: A Versatile Tool for the Structural and Functional Annotation of Ion Channel Pores. Journal of Molecular Biology. PMID 31220459 DOI: 10.1016/j.jmb.2019.06.003  1
2019 Schewe M, Sun H, Mert Ü, Mackenzie A, Pike ACW, Schulz F, Constantin C, Vowinkel KS, Conrad LJ, Kiper AK, Gonzalez W, Musinszki M, Tegtmeier M, Pryde DC, Belabed H, ... ... Tucker SJ, et al. A pharmacological master key mechanism that unlocks the selectivity filter gate in K channels. Science (New York, N.Y.). 363: 875-880. PMID 30792303 DOI: 10.1126/science.aav0569  1
2018 Rao S, Lynch CI, Klesse G, Oakley GE, Stansfeld PJ, Tucker SJ, Sansom MSP. Water and hydrophobic gates in ion channels and nanopores. Faraday Discussions. PMID 29969132 DOI: 10.1039/c8fd00013a  1
2017 Clausen MV, Jarerattanachat V, Carpenter EP, Sansom MSP, Tucker SJ. Asymmetric mechanosensitivity in a eukaryotic ion channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923939 DOI: 10.1073/pnas.1708990114  1
2017 Nematian-Ardestani E, Jarerattanachat V, Aryal P, Sansom MSP, Tucker SJ. The Effects of Stretch Activation on Ionic Selectivity of the TREK-2 K2P K(+) Channel. Channels (Austin, Tex.). 0. PMID 28723241 DOI: 10.1080/19336950.2017.1356955  1
2017 Lacin E, Aryal P, Glaaser IW, Bodhinathan K, Tsai E, Marsh N, Tucker SJ, Sansom MSP, Slesinger PA. Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology. PMID 28720589 DOI: 10.1085/jgp.201711801  1
2017 Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike AC, Carpenter EP, Baukrowitz T, Sansom MS, Tucker SJ. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Structure (London, England : 1993). PMID 28392258 DOI: 10.1016/j.str.2017.03.006  1
2017 Rao S, Klesse G, Stansfeld PJ, Tucker SJ, Sansom MS. A BEST Example of Channel Structure Annotation by Molecular Simulation. Channels (Austin, Tex.). 0. PMID 28319451 DOI: 10.1080/19336950.2017.1306163  1
2016 Trick JL, Chelvaniththilan S, Klesse G, Aryal P, Wallace EJ, Tucker SJ, Sansom MS. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure (London, England : 1993). PMID 27866853 DOI: 10.1016/j.str.2016.10.005  1
2016 Reed AP, Bucci G, Abd-Wahab F, Tucker SJ. Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. Plos One. 11: e0160114. PMID 27442432 DOI: 10.1371/journal.pone.0160114  1
2016 McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states. The Journal of General Physiology. 147: 497-505. PMID 27241700 DOI: 10.1085/jgp.201611601  1
2016 Reed AP, Bucci G, Abd-Wahab F, Tucker SJ. Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. Plos One. 11: e0156456. PMID 27228168 DOI: 10.1371/journal.pone.0156456  1
2016 Schewe M, Nematian-Ardestani E, Sun H, Musinszki M, Cordeiro S, Bucci G, de Groot BL, Tucker SJ, Rapedius M, Baukrowitz T. A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels. Cell. 164: 937-49. PMID 26919430 DOI: 10.1016/j.cell.2016.02.002  1
2015 Zubcevic L, Wang S, Bavro VN, Lee SJ, Nichols CG, Tucker SJ. Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic 'Inward Rectifier' (NirBac) channels. Scientific Reports. 5: 15305. PMID 26470642 DOI: 10.1038/srep15305  1
2015 Beale JH, Parker JL, Samsudin F, Barrett AL, Senan A, Bird LE, Scott D, Owens RJ, Sansom MS, Tucker SJ, Meredith D, Fowler PW, Newstead S. Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport. Structure (London, England : 1993). 23: 1889-99. PMID 26320580 DOI: 10.1016/j.str.2015.07.016  1
2015 Parolin Schnekenberg R, Perkins EM, Miller JW, Davies WI, D'Adamo MC, Pessia M, Fawcett KA, Sims D, Gillard E, Hudspith K, Skehel P, Williams J, O'Regan M, Jayawant S, Jefferson R, ... ... Tucker SJ, et al. De novo point mutations in patients diagnosed with ataxic cerebral palsy. Brain : a Journal of Neurology. 138: 1817-32. PMID 25981959 DOI: 10.1093/brain/awv117  1
2015 Trick JL, Aryal P, Tucker SJ, Sansom MS. Molecular simulation studies of hydrophobic gating in nanopores and ion channels. Biochemical Society Transactions. 43: 146-50. PMID 25849908 DOI: 10.1042/BST20140256  1
2015 Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, ... ... Tucker SJ, et al. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science (New York, N.Y.). 347: 1256-9. PMID 25766236 DOI: 10.1126/science.1261512  1
2015 Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel. Channels (Austin, Tex.). 9: 44-9. PMID 25487004 DOI: 10.4161/19336950.2014.981987  1
2015 Aryal P, Sansom MS, Tucker SJ. Hydrophobic gating in ion channels. Journal of Molecular Biology. 427: 121-30. PMID 25106689 DOI: 10.1016/j.jmb.2014.07.030  1
2015 Beale JH, Parker JL, Samsudin F, Barrett AL, Senan A, Bird LE, Scott D, Owens RJ, Sansom MSP, Tucker SJ, Meredith D, Fowler PW, Newstead S. Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport Structure. DOI: 10.1016/j.str.2015.07.016  1
2014 D'Adamo MC, Gallenmüller C, Servettini I, Hartl E, Tucker SJ, Arning L, Biskup S, Grottesi A, Guglielmi L, Imbrici P, Bernasconi P, Di Giovanni G, Franciolini F, Catacuzzeno L, Pessia M, et al. Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene. Frontiers in Physiology. 5: 525. PMID 25642194 DOI: 10.3389/fphys.2014.00525  1
2014 Fowler PW, Bollepalli MK, Rapedius M, Nematian-Ardestani E, Shang L, Sansom MS, Tucker SJ, Baukrowitz T. Insights into the structural nature of the transition state in the Kir channel gating pathway. Channels (Austin, Tex.). 8: 551-5. PMID 25483285 DOI: 10.4161/19336950.2014.962371  1
2014 Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel. Nature Communications. 5: 4377. PMID 25001086 DOI: 10.1038/ncomms5377  1
2014 Bollepalli MK, Fowler PW, Rapedius M, Shang L, Sansom MS, Tucker SJ, Baukrowitz T. State-dependent network connectivity determines gating in a K+ channel. Structure (London, England : 1993). 22: 1037-46. PMID 24980796 DOI: 10.1016/j.str.2014.04.018  1
2014 Veale EL, Al-Moubarak E, Bajaria N, Omoto K, Cao L, Tucker SJ, Stevens EB, Mathie A. Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels. Molecular Pharmacology. 85: 671-81. PMID 24509840 DOI: 10.1124/mol.113.091199  1
2014 Zubcevic L, Bavro VN, Muniz JR, Schmidt MR, Wang S, De Zorzi R, Venien-Bryan C, Sansom MS, Nichols CG, Tucker SJ. Control of KirBac3.1 potassium channel gating at the interface between cytoplasmic domains. The Journal of Biological Chemistry. 289: 143-51. PMID 24257749 DOI: 10.1074/jbc.M113.501833  1
2013 Schmidt MR, Stansfeld PJ, Tucker SJ, Sansom MS. Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel. Biochemistry. 52: 279-81. PMID 23270460 DOI: 10.1021/bi301350s  1
2012 Rapedius M, Schmidt MR, Sharma C, Stansfeld PJ, Sansom MS, Baukrowitz T, Tucker SJ. State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1. Channels (Austin, Tex.). 6: 473-8. PMID 22991046 DOI: 10.4161/chan.22153  1
2012 Andres-Enguix I, Shang L, Stansfeld PJ, Morahan JM, Sansom MS, Lafrenière RG, Roy B, Griffiths LR, Rouleau GA, Ebers GC, Cader ZM, Tucker SJ. Functional analysis of missense variants in the TRESK (KCNK18) K channel. Scientific Reports. 2: 237. PMID 22355750 DOI: 10.1038/srep00237  1
2012 Bavro VN, De Zorzi R, Schmidt MR, Muniz JR, Zubcevic L, Sansom MS, Vénien-Bryan C, Tucker SJ. Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating. Nature Structural & Molecular Biology. 19: 158-63. PMID 22231399 DOI: 10.1038/nsmb.2208  1
2011 Piechotta PL, Rapedius M, Stansfeld PJ, Bollepalli MK, Ehrlich G, Erhlich G, Andres-Enguix I, Fritzenschaft H, Decher N, Sansom MS, Tucker SJ, Baukrowitz T. The pore structure and gating mechanism of K2P channels. The Embo Journal. 30: 3607-19. PMID 21822218 DOI: 10.1038/emboj.2011.268  1
2011 Paulais M, Bloch-Faure M, Picard N, Jacques T, Ramakrishnan SK, Keck M, Sohet F, Eladari D, Houillier P, Lourdel S, Teulon J, Tucker SJ. Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome. Proceedings of the National Academy of Sciences of the United States of America. 108: 10361-6. PMID 21633011 DOI: 10.1073/pnas.1101400108  1
2011 Leptihn S, Thompson JR, Ellory JC, Tucker SJ, Wallace MI. In vitro reconstitution of eukaryotic ion channels using droplet interface bilayers. Journal of the American Chemical Society. 133: 9370-5. PMID 21591742 DOI: 10.1021/ja200128n  1
2011 Trapp S, Tucker SJ, Gourine AV. Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16). Experimental Physiology. 96: 451-9. PMID 21239463 DOI: 10.1113/expphysiol.2010.055848  1
2011 D'Adamo MC, Shang L, Imbrici P, Brown SD, Pessia M, Tucker SJ. Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity. The Journal of Biological Chemistry. 286: 192-8. PMID 21047793 DOI: 10.1074/jbc.M110.189290  1
2010 Wang SC, Politis A, Di Bartolo N, Bavro VN, Tucker SJ, Booth PJ, Barrera NP, Robinson CV. Ion mobility mass spectrometry of two tetrameric membrane protein complexes reveals compact structures and differences in stability and packing. Journal of the American Chemical Society. 132: 15468-70. PMID 20949939 DOI: 10.1021/ja104312e  1
2010 Paynter JJ, Andres-Enguix I, Fowler PW, Tottey S, Cheng W, Enkvetchakul D, Bavro VN, Kusakabe Y, Sansom MS, Robinson NJ, Nichols CG, Tucker SJ. Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains. The Journal of Biological Chemistry. 285: 40754-61. PMID 20876570 DOI: 10.1074/jbc.M110.175687  1
2010 Lafrenière RG, Cader MZ, Poulin JF, Andres-Enguix I, Simoneau M, Gupta N, Boisvert K, Lafrenière F, McLaughlan S, Dubé MP, Marcinkiewicz MM, Ramagopalan S, Ansorge O, Brais B, Sequeiros J, ... ... Tucker SJ, et al. A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. Nature Medicine. 16: 1157-60. PMID 20871611 DOI: 10.1038/nm.2216  1
2010 Paynter JJ, Shang L, Bollepalli MK, Baukrowitz T, Tucker SJ. Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels. Channels (Austin, Tex.). 4: 390-7. PMID 20699659 DOI: 10.4161/chan.4.5.13006  1
2010 Gupta S, Bavro VN, D'Mello R, Tucker SJ, Vénien-Bryan C, Chance MR. Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry. Structure (London, England : 1993). 18: 839-46. PMID 20637420 DOI: 10.1016/j.str.2010.04.012  1
2009 Shang L, Ranson SV, Tucker SJ. Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis. Biochemical and Biophysical Research Communications. 388: 501-5. PMID 19665991 DOI: 10.1016/j.bbrc.2009.08.032  1
2009 Imbrici P, Grottesi A, D'Adamo MC, Mannucci R, Tucker SJ, Pessia M. Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties. Channels (Austin, Tex.). 3: 39-45. PMID 19202350  1
2008 Imbrici P, Gualandi F, D'Adamo MC, Masieri MT, Cudia P, De Grandis D, Mannucci R, Nicoletti I, Tucker SJ, Ferlini A, Pessia M. A novel KCNA1 mutation identified in an Italian family affected by episodic ataxia type 1 Neuroscience. 157: 577-587. PMID 18926884 DOI: 10.1016/j.neuroscience.2008.09.022  1
2008 Paynter JJ, Sarkies P, Andres-Enguix I, Tucker SJ. Genetic selection of activatory mutations in KcsA. Channels (Austin, Tex.). 2: 413-8. PMID 18797191 DOI: 10.4161/chan.2.6.6874  1
2008 Nagaoka Y, Shang L, Banerjee A, Bayley H, Tucker SJ. Peptide backbone mutagenesis of putative gating hinges in a potassium ion channel. Chembiochem : a European Journal of Chemical Biology. 9: 1725-8. PMID 18543260 DOI: 10.1002/cbic.200800133  1
2008 Tucker SJ, Baukrowitz T. How highly charged anionic lipids bind and regulate ion channels. The Journal of General Physiology. 131: 431-8. PMID 18411329 DOI: 10.1085/jgp.200709936  1
2008 Shang L, Tucker SJ. Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels. European Biophysics Journal : Ebj. 37: 165-71. PMID 17657484 DOI: 10.1007/s00249-007-0206-7  1
2007 Rapedius M, Paynter JJ, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T. Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing. Channels (Austin, Tex.). 1: 327-30. PMID 18690035  1
2007 Rapedius M, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T. H bonding at the helix-bundle crossing controls gating in Kir potassium channels. Neuron. 55: 602-14. PMID 17698013 DOI: 10.1016/j.neuron.2007.07.026  1
2007 Haider S, Khalid S, Tucker SJ, Ashcroft FM, Sansom MS. Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study. Biochemistry. 46: 3643-52. PMID 17326663 DOI: 10.1021/bi062210f  1
2006 Rapedius M, Haider S, Browne KF, Shang L, Sansom MS, Baukrowitz T, Tucker SJ. Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel. Embo Reports. 7: 611-6. PMID 16641935 DOI: 10.1038/sj.embor.7400678  1
2006 Sun S, Gan JH, Paynter JJ, Tucker SJ. Cloning and functional characterization of a superfamily of microbial inwardly rectifying potassium channels. Physiological Genomics. 26: 1-7. PMID 16595742 DOI: 10.1152/physiolgenomics.00026.2006  1
2005 Rapedius M, Soom M, Shumilina E, Schulze D, Schönherr R, Kirsch C, Lang F, Tucker SJ, Baukrowitz T. Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels. The Journal of Biological Chemistry. 280: 30760-7. PMID 15980413 DOI: 10.1074/jbc.M503503200  1
2005 Shang L, Lucchese CJ, Haider S, Tucker SJ. Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility. Brain Research. Molecular Brain Research. 139: 178-83. PMID 15936844 DOI: 10.1016/j.molbrainres.2005.05.003  1
2003 Casamassima M, D'Adamo MC, Pessia M, Tucker SJ. Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels. The Journal of Biological Chemistry. 278: 43533-40. PMID 12923169 DOI: 10.1074/jbc.M306596200  1
2003 Konstas AA, Korbmacher C, Tucker SJ. Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels. American Journal of Physiology. Cell Physiology. 284: C910-7. PMID 12456399 DOI: 10.1152/ajpcell.00479.2002  1
2002 Konstas AA, Koch JP, Tucker SJ, Korbmacher C. Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel. The Journal of Biological Chemistry. 277: 25377-84. PMID 11994290 DOI: 10.1074/jbc.M201925200  1
2002 Konstas AA, Dabrowski M, Korbmacher C, Tucker SJ. Intrinsic sensitivity of Kir1.1 (ROMK) to glibenclamide in the absence of SUR2B. Implications for the identity of the renal ATP-regulated secretory K+ channel. The Journal of Biological Chemistry. 277: 21346-51. PMID 11927600 DOI: 10.1074/jbc.M202005200  1
2001 Jones PA, Tucker SJ, Ashcroft FM. Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2. Febs Letters. 508: 85-9. PMID 11707273 DOI: 10.1016/S0014-5793(01)03023-X  1
2001 Pessia M, Imbrici P, Cristina D'Adamo M, Salvatore L, Tucker SJ. Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1 Journal of Physiology. 532: 359-367. PMID 11306656 DOI: 10.1111/j.1469-7793.2001.0359f.x  1
2000 Imbrici P, Tucker SJ, D'Adamo MC, Pessia M. Role of receptor protein tyrosine phosphatase α (RPTPα) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels Pflugers Archiv European Journal of Physiology. 441: 257-262. PMID 11211111 DOI: 10.1007/s004240000406  1
2000 Gribble FM, Loussouarn G, Tucker SJ, Zhao C, Nichols CG, Ashcroft FM. A novel method for measurement of submembrane ATP concentration. The Journal of Biological Chemistry. 275: 30046-9. PMID 10866996 DOI: 10.1074/jbc.M001010200  1
2000 Tanabe K, Tucker SJ, Ashcroft FM, Proks P, Kioka N, Amachi T, Ueda K. Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide. Biochemical and Biophysical Research Communications. 272: 316-9. PMID 10833411 DOI: 10.1006/bbrc.2000.2780  1
2000 Tucker SJ, Imbrici P, Salvatore L, D'Adamo MC, Pessia M. pH Dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia Journal of Biological Chemistry. 275: 16404-16407. PMID 10764726 DOI: 10.1074/jbc.C000127200  1
1999 Matsuo M, Tucker SJ, Ashcroft FM, Amachi T, Ueda K. NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1. Febs Letters. 458: 292-4. PMID 10570926 DOI: 10.1016/S0014-5793(99)01170-9  1
1999 Tucker SJ, Ashcroft FM. Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2. The Journal of Biological Chemistry. 274: 33393-7. PMID 10559219 DOI: 10.1074/jbc.274.47.33393  1
1999 Reimann F, Ryder TJ, Tucker SJ, Ashcroft FM. The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP. The Journal of Physiology. 520: 661-9. PMID 10545134 DOI: 10.1111/j.1469-7793.1999.00661.x  1
1999 Reimann F, Tucker SJ, Proks P, Ashcroft FM. Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor. The Journal of Physiology. 518: 325-36. PMID 10381582 DOI: 10.1111/j.1469-7793.1999.0325p.x  1
1999 Baukrowitz T, Tucker SJ, Schulte U, Benndorf K, Ruppersberg JP, Fakler B. Inward rectification in K(ATP) channels: A pH switch in the pore Embo Journal. 18: 847-853. PMID 10022827 DOI: 10.1093/emboj/18.4.847  1
1999 Tanabe K, Tucker SJ, Matsuo M, Proks P, Ashcroft FM, Seino S, Amachi T, Ueda K. Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. The Journal of Biological Chemistry. 274: 3931-3. PMID 9933580 DOI: 10.1074/jbc.274.7.3931  1
1999 Proks P, Gribble FM, Adhikari R, Tucker SJ, Ashcroft FM. Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP. The Journal of Physiology. 514: 19-25. PMID 9831713 DOI: 10.1111/j.1469-7793.1999.019af.x  1
1998 Baukrowitz T, Schulte U, Oliver D, Herlitze S, Krauter T, Tucker SJ, Ruppersberg JP, Fakler B. PIP2 and PIP as determinants for ATP inhibition of KATP channels. Science (New York, N.Y.). 282: 1141-4. PMID 9804555  1
1998 Takada Y, Yamada K, Taguchi Y, Kino K, Matsuo M, Tucker SJ, Komano T, Amachi T, Ueda K. Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein. Biochimica Et Biophysica Acta. 1373: 131-6. PMID 9733949 DOI: 10.1016/S0005-2736(98)00099-6  1
1998 Gribble FM, Tucker SJ, Seino S, Ashcroft FM. Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels. Diabetes. 47: 1412-8. PMID 9726229  1
1998 Trapp S, Proks P, Tucker SJ, Ashcroft FM. Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP. The Journal of General Physiology. 112: 333-49. PMID 9725893 DOI: 10.1085/jgp.112.3.333  1
1998 Trapp S, Tucker SJ, Ashcroft FM. Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification. The Journal of General Physiology. 112: 325-32. PMID 9725892 DOI: 10.1085/jgp.112.3.325  1
1998 Tucker SJ, Ashcroft FM. A touching case of channel regulation: the ATP-sensitive K+ channel. Current Opinion in Neurobiology. 8: 316-20. PMID 9687347 DOI: 10.1016/S0959-4388(98)80055-X  1
1998 Tucker SJ, Gribble FM, Proks P, Trapp S, Ryder TJ, Haug T, Reimann F, Ashcroft FM. Molecular determinants of KATP channel inhibition by ATP. The Embo Journal. 17: 3290-6. PMID 9628866 DOI: 10.1093/emboj/17.12.3290  1
1998 Gribble FM, Tucker SJ, Haug T, Ashcroft FM. MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. Proceedings of the National Academy of Sciences of the United States of America. 95: 7185-90. PMID 9618560 DOI: 10.1073/pnas.95.12.7185  1
1998 Singer TD, Tucker SJ, Marshall WS, Higgins CF. A divergent CFTR homologue: highly regulated salt transport in the euryhaline teleost F. heteroclitus. The American Journal of Physiology. 274: C715-23. PMID 9530103  1
1997 Gribble FM, Tucker SJ, Ashcroft FM. The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation. The Journal of Physiology. 504: 35-45. PMID 9350615 DOI: 10.1111/j.1469-7793.1997.00035.x  1
1997 Trapp S, Tucker SJ, Ashcroft FM. Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits. Proceedings of the National Academy of Sciences of the United States of America. 94: 8872-7. PMID 9238070 DOI: 10.1073/pnas.94.16.8872  1
1997 Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM. Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. Nature. 387: 179-83. PMID 9144288 DOI: 10.1038/387179a0  1
1997 Gribble FM, Tucker SJ, Ashcroft FM. The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. The Embo Journal. 16: 1145-52. PMID 9135131 DOI: 10.1093/emboj/16.6.1145  1
1996 Tucker SJ, Pessia M, Adelman JP. Muscarine-gated K+ channel: Subunit stoichiometry and structural domains essential for G protein stimulation American Journal of Physiology - Heart and Circulatory Physiology. 271: H379-H385. PMID 8760196  1
1996 Tucker SJ, Pessia M, Moorhouse AJ, Gribble F, Ashcroft FM, Maylie J, Adelman JP. Heteromeric channel formation and Ca2+-free media reduce the toxic effect of the weaver K(ir), 3.2 allele Febs Letters. 390: 253-257. PMID 8706871 DOI: 10.1016/0014-5793(96)00635-7  1
1996 Pessia M, Tucker SJ, Lee K, Bond CT, Adelman JP. Subunit positional effects revealed by novel heteromeric inwardly rectifying K+ channels Embo Journal. 15: 2980-2987. PMID 8670799  1
1996 Tucker SJ, Bond CT, Herson P, Pessia M, Adelman JP. Inhibitory interactions between two inward rectifier K+ channel subunits mediated by the transmembrane domains Journal of Biological Chemistry. 271: 5866-5870. PMID 8621458 DOI: 10.1074/jbc.271.10.5866  1
1995 Tucker SJ, James MR, Adelman JP. Assignment of KATP-1, the Cardiac ATP-Sensitive Potassium Channel Gene (KCNJ5), to Human Chromosome 11q24 Genomics. 28: 127-128. PMID 7590741 DOI: 10.1006/geno.1995.1121  1
1992 Tucker SJ, Tannahill D, Higgins CF. Identification and developmental expression of the Xenopus laevis cystic fibrosis transmembrane conductance regulator gene. Human Molecular Genetics. 1: 77-82. PMID 1284470 DOI: 10.1093/hmg/1.2.77  1
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