☰

Michael B. Harbut, Ph.D. - Publications

Affiliations: 
2012 Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology, Parasitology Biology, Biochemistry, Genetics
Tree Info Grants Similar researchers PubMed Report error

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Harbut MB, Liu R, Yang B, Yano T, Vilcheze C, Lockner J, Guo H, Franzblau SG, Petrassi M, Jacobs WR, Rubin H, Chatterjee AK, Wang F. Small molecules targeting Mycobacterium tuberculosis type II NADH dehydrogenase with antimycobacterial activity. Angewandte Chemie (International Ed. in English). PMID 29388301 DOI: 10.1002/Anie.201800260  0.373
2017 Mietton F, Ferri E, Champleboux M, Zala N, Maubon D, Zhou Y, Harbut M, Spittler D, Garnaud C, Courçon M, Chauvel M, d'Enfert C, Kashemirov BA, Hull M, Cornet M, et al. Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nature Communications. 8: 15482. PMID 28516956 DOI: 10.1038/Ncomms15482  0.418
2015 Harbut MB, Vilchèze C, Luo X, Hensler ME, Guo H, Yang B, Chatterjee AK, Nizet V, Jacobs WR, Schultz PG, Wang F. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 112: 4453-8. PMID 25831516 DOI: 10.1073/Pnas.1504022112  0.352
2012 Harbut MB, Patel BA, Yeung BK, McNamara CW, Bright AT, Ballard J, Supek F, Golde TE, Winzeler EA, Diagana TT, Greenbaum DC. Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design. Proceedings of the National Academy of Sciences of the United States of America. 109: 21486-91. PMID 23236186 DOI: 10.1073/Pnas.1216016110  0.654
2011 Harbut MB, Velmourougane G, Dalal S, Reiss G, Whisstock JC, Onder O, Brisson D, McGowan S, Klemba M, Greenbaum DC. Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases. Proceedings of the National Academy of Sciences of the United States of America. 108: E526-34. PMID 21844374 DOI: 10.1073/Pnas.1105601108  0.669
2011 Velmourougane G, Harbut MB, Dalal S, McGowan S, Oellig CA, Meinhardt N, Whisstock JC, Klemba M, Greenbaum DC. Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase. Journal of Medicinal Chemistry. 54: 1655-66. PMID 21366301 DOI: 10.1021/Jm101227T  0.624
2009 Chandramohanadas R, Davis PH, Beiting DP, Harbut MB, Darling C, Velmourougane G, Lee MY, Greer PA, Roos DS, Greenbaum DC. Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science (New York, N.Y.). 324: 794-7. PMID 19342550 DOI: 10.1126/Science.1171085  0.637
2008 Harbut MB, Velmourougane G, Reiss G, Chandramohanadas R, Greenbaum DC. Development of bestatin-based activity-based probes for metallo-aminopeptidases. Bioorganic & Medicinal Chemistry Letters. 18: 5932-6. PMID 18823778 DOI: 10.1016/J.Bmcl.2008.09.021  0.594
2008 Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. Journal of Medicinal Chemistry. 51: 545-52. PMID 18173229 DOI: 10.1021/Jm070760L  0.622
Show low-probability matches.