| Year |
Citation |
Score |
| 2005 |
Mulholland PJ, Self RL, Stepanyan TD, Little HJ, Littleton JM, Prendergast MA. Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro. Neuroscience. 135: 1129-39. PMID 16165302 DOI: 10.1016/J.Neuroscience.2005.06.077 |
0.494 |
|
| 2005 |
Mulholland PJ, Self RL, Harris BR, Little HJ, Littleton JM, Prendergast MA. Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures. Alcoholism, Clinical and Experimental Research. 29: 871-81. PMID 15897733 DOI: 10.1097/01.Alc.0000163509.27577.Da |
0.558 |
|
| 2004 |
Clark A, Little HJ. Interactions between low concentrations of ethanol and nicotine on firing rate of ventral tegmental dopamine neurones. Drug and Alcohol Dependence. 75: 199-206. PMID 15276226 DOI: 10.1016/j.drugalcdep.2004.03.001 |
0.396 |
|
| 2004 |
Brooks SP, Hennebry G, Croft AP, Thomas A, Little HJ. Effects of corticosterone on place conditioning to ethanol. Psychopharmacology. 174: 291-9. PMID 14767631 DOI: 10.1007/s00213-003-1745-y |
0.453 |
|
| 2003 |
Diana M, Brodie M, Muntoni A, Puddu MC, Pillolla G, Steffensen S, Spiga S, Little HJ. Enduring effects of chronic ethanol in the CNS: basis for alcoholism. Alcoholism, Clinical and Experimental Research. 27: 354-61. PMID 12605085 DOI: 10.1097/01.Alc.0000057121.36127.19 |
0.414 |
|
| 2002 |
Brooks SP, Hennebry G, McAlpin GP, Norman G, Little HJ. Nimodipine prevents the effects of ethanol in tests of memory. Neuropharmacology. 42: 577-85. PMID 11955528 DOI: 10.1016/S0028-3908(02)00006-0 |
0.486 |
|
| 2002 |
O'Callaghan MJ, Croft AP, Watson WP, Brooks SP, Little HJ. Low alcohol preference among the "high alcohol preference" C57/BL10 mice; factors affecting such preference. Pharmacology, Biochemistry, and Behavior. 72: 475-81. PMID 11900822 DOI: 10.1016/S0091-3057(02)00717-7 |
0.324 |
|
| 2002 |
Watson WP, Little HJ. Selectivity of the protective effects of dihydropyridine calcium channel antagonists against the ethanol withdrawal syndrome. Brain Research. 930: 111-22. PMID 11879801 DOI: 10.1016/S0006-8993(02)02236-9 |
0.49 |
|
| 2001 |
Bailey CP, O'Callaghan MJ, Croft AP, Manley SJ, Little HJ. Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption. Neuropharmacology. 41: 989-99. PMID 11747903 DOI: 10.1016/S0028-3908(01)00146-0 |
0.301 |
|
| 2001 |
Holt JD, Watson WP, Little HJ. Studies on a model of long term alcohol drinking. Behavioural Brain Research. 123: 193-200. PMID 11399331 DOI: 10.1016/S0166-4328(01)00206-6 |
0.466 |
|
| 2000 |
Bailey CP, Andrews N, McKnight AT, Hughes J, Little HJ. Prolonged changes in neurochemistry of dopamine neurones after chronic ethanol consumption. Pharmacology, Biochemistry, and Behavior. 66: 153-61. PMID 10837855 DOI: 10.1016/S0091-3057(00)00230-6 |
0.374 |
|
| 2000 |
Little HJ, Clark A, Watson WP. Investigations into pharmacological antagonism of general anaesthesia. British Journal of Pharmacology. 129: 1755-63. PMID 10780983 DOI: 10.1038/sj.bjp.0703262 |
0.406 |
|
| 2000 |
Smith JW, Little HJ. Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance. Brain Research. 863: 9-19. PMID 10773188 DOI: 10.1016/S0006-8993(00)02064-3 |
0.582 |
|
| 2000 |
Cole JC, Littleton JM, Little HJ. Acamprosate, but not naltrexone, inhibits conditioned abstinence behaviour associated with repeated ethanol administration and exposure to a plus-maze. Psychopharmacology. 147: 403-11. PMID 10672634 DOI: 10.1007/S002130050009 |
0.314 |
|
| 1999 |
Wilson J, Woodruff GN, Little HJ. Concurrent chronic administration of a CCK(B) antagonist can decrease tolerance to the ataxic effects of ethanol. Addiction Biology. 4: 35-45. PMID 20575768 DOI: 10.1080/13556219971821 |
0.542 |
|
| 1999 |
Smith JW, Watson WP, Stephens DN, Little HJ. The calcium channel antagonist, nimodipine, decreases operant self-administration of low concentrations of ethanol. Behavioural Pharmacology. 10: 793-802. PMID 10780295 |
0.56 |
|
| 1999 |
Little HJ. The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanol. Pharmacology & Therapeutics. 84: 333-53. PMID 10665833 DOI: 10.1016/S0163-7258(99)00040-6 |
0.56 |
|
| 1999 |
Cole JC, Littleton JM, Little HJ. Effects of repeated ethanol administration in the plus maze; a simple model for conditioned abstinence behaviour. Psychopharmacology. 142: 270-9. PMID 10208319 DOI: 10.1007/S002130050889 |
0.536 |
|
| 1999 |
Watson WP, Little HJ. Correlation between increases in dihydropyridine binding in vivo and behavioural signs of ethanol withdrawal in mice. Alcohol and Alcoholism (Oxford, Oxfordshire). 34: 35-42. PMID 10075399 DOI: 10.1093/alcalc/34.1.35 |
0.414 |
|
| 1998 |
Watson WP, Homewood N, Little HJ. Differing acute interactions of ethanol with two structurally related dihydropyridines, nitrendipine and felodipine. Brain Research Bulletin. 47: 337-43. PMID 9886785 DOI: 10.1016/S0361-9230(98)00085-9 |
0.593 |
|
| 1998 |
Bailey CP, Manley SJ, Watson WP, Wonnacott S, Molleman A, Little HJ. Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability. Brain Research. 803: 144-52. PMID 9729345 DOI: 10.1016/S0006-8993(98)00654-4 |
0.491 |
|
| 1998 |
Wilson J, Watson WP, Little HJ. CCK(B) antagonists protect against anxiety-related behaviour produced by ethanol withdrawal, measured using the elevated plus maze. Psychopharmacology. 137: 120-31. PMID 9629998 DOI: 10.1007/s002130050601 |
0.491 |
|
| 1998 |
Wilson J, Little HJ. CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome. Pharmacology, Biochemistry, and Behavior. 59: 967-73. PMID 9586857 DOI: 10.1016/S0091-3057(97)00536-4 |
0.45 |
|
| 1998 |
Bailey CP, Molleman A, Little HJ. Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption. British Journal of Pharmacology. 123: 215-22. PMID 9489608 DOI: 10.1038/sj.bjp.0701596 |
0.581 |
|
| 1997 |
Watson WP, Robinson E, Little HJ. The novel anticonvulsant, gabapentin, protects against both convulsant and anxiogenic aspects of the ethanol withdrawal syndrome. Neuropharmacology. 36: 1369-75. PMID 9423924 DOI: 10.1016/S0028-3908(97)00118-4 |
0.495 |
|
| 1997 |
Manley SJ, Little HJ. Enhancement of amphetamine- and cocaine-induced locomotor activity after chronic ethanol administration. The Journal of Pharmacology and Experimental Therapeutics. 281: 1330-9. PMID 9190869 |
0.49 |
|
| 1996 |
Ripley TL, Whittington MA, Butterworth AR, Little HJ. Ethanol withdrawal hyperexcitability in vivo and in isolated mouse hippocampal slices. Alcohol and Alcoholism (Oxford, Oxfordshire). 31: 347-57. PMID 8879281 DOI: 10.1093/Oxfordjournals.Alcalc.A008161 |
0.732 |
|
| 1995 |
Ripley TL, Little HJ. Ethanol withdrawal hyperexcitability in vitro is selectively decreased by a competitive NMDA receptor antagonist. Brain Research. 699: 1-11. PMID 8616595 DOI: 10.1016/0006-8993(95)00445-V |
0.523 |
|
| 1995 |
Watson WP, Little HJ. Identification of distinct components, with different time courses, of the changes in response to convulsive stimuli during ethanol withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 272: 876-84. PMID 7853206 |
0.46 |
|
| 1995 |
Ripley TL, Little HJ. Effects on ethanol withdrawal hyperexcitability of chronic treatment with a competitive N-methyl-D-aspartate receptor antagonist. The Journal of Pharmacology and Experimental Therapeutics. 272: 112-8. PMID 7815323 |
0.579 |
|
| 1995 |
Mead AJ, Little HJ. Do GABAB receptors have a role in causing behavioural hyperexcitability, both during ethanol withdrawal and in naive mice? Psychopharmacology. 117: 232-9. PMID 7753972 DOI: 10.1007/BF02245192 |
0.505 |
|
| 1995 |
Whittington MA, Lambert JD, Little HJ. Increased NMDA receptor and calcium channel activity underlying ethanol withdrawal hyperexcitability. Alcohol and Alcoholism (Oxford, Oxfordshire). 30: 105-14. PMID 7748267 DOI: 10.1093/Oxfordjournals.Alcalc.A045686 |
0.682 |
|
| 1995 |
Ripley TL, Little HJ. Nitrendipine prevents the decrease caused by chronic ethanol intake in the maintenance of tetanic long-term potentiation. Experimental Brain Research. 103: 1-8. PMID 7615026 DOI: 10.1007/BF00241959 |
0.623 |
|
| 1995 |
Molleman A, Little HJ. Increases in non-N-methyl-D-aspartate glutamatergic transmission, but no change in gamma-aminobutyric acidB transmission, in CA1 neurons during withdrawal from in vivo chronic ethanol treatment. The Journal of Pharmacology and Experimental Therapeutics. 274: 1035-41. PMID 7562466 |
0.458 |
|
| 1994 |
Rabbani M, Brown J, Butterworth AR, Little HJ. Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal. Pharmacology, Biochemistry, and Behavior. 47: 675-80. PMID 8208788 DOI: 10.1016/0091-3057(94)90173-2 |
0.517 |
|
| 1994 |
Watson WP, Little HJ. Interactions between diltiazem and ethanol: differences from those seen with dihydropyridine calcium channel antagonists. Psychopharmacology. 114: 329-36. PMID 7838926 DOI: 10.1007/BF02244856 |
0.632 |
|
| 1994 |
Watson WP, Little HJ. Effects of diltiazem in convulsive states differ from those previously reported for dihydropyridine calcium channel antagonists. Psychopharmacology. 114: 321-8. PMID 7530854 DOI: 10.1007/BF02244855 |
0.335 |
|
| 1994 |
Watson WP, Misra A, Cross AJ, Green AR, Little HJ. The differential effects of felodipine and nitrendipine on cerebral dihydropyridine binding ex vivo and the ethanol withdrawal syndrome in mice. British Journal of Pharmacology. 112: 1017-24. PMID 7524989 |
0.467 |
|
| 1993 |
Whittington MA, Lambert JD, Little HJ. Increases in synaptic activation of calcium current as a mechanism for generation of ethanol withdrawal seizures. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 391-4. PMID 7748328 |
0.646 |
|
| 1993 |
Little HJ, Dolin SJ, Whittington MA. Calcium channel antagonists prevent adaptive responses to ethanol. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 263-7. PMID 7748308 |
0.723 |
|
| 1993 |
Whittington MA, Little HJ. Changes in voltage-operated calcium channels modify ethanol withdrawal hyperexcitability in mouse hippocampal slices. Experimental Physiology. 78: 347-70. PMID 7687135 DOI: 10.1113/Expphysiol.1993.Sp003690 |
0.69 |
|
| 1992 |
Whittington MA, Butterworth AR, Dolin SJ, Patch TL, Little HJ. The effects of chronic treatment with the dihydropyridine, Bay K 8644, on hyperexcitability due to ethanol withdrawal, in vivo and in vitro. British Journal of Pharmacology. 105: 285-92. PMID 1373096 DOI: 10.1111/J.1476-5381.1992.Tb14247.X |
0.677 |
|
| 1992 |
Whittington MA, Little HJ, Lambert JD. Changes in intrinsic inhibition in isolated hippocampal slices during ethanol withdrawal; lack of correlation with withdrawal hyperexcitability. British Journal of Pharmacology. 107: 521-7. PMID 1330182 DOI: 10.1111/J.1476-5381.1992.Tb12777.X |
0.593 |
|
| 1992 |
Little HJ, Andreasen M, Lambert JD. Chronic treatment with a benzodiazepine agonist in vivo increases the actions of the benzodiazepine partial inverse agonist, FG7142, on the hippocampal slice in vitro. Brain Research. 573: 243-50. PMID 1324078 DOI: 10.1016/0006-8993(92)90769-6 |
0.304 |
|
| 1992 |
Littleton J, Little H, Laverty R. Role of neuronal calcium channels in ethanol dependence: from cell cultures to the intact animal. Annals of the New York Academy of Sciences. 654: 324-34. PMID 1321573 DOI: 10.1111/j.1749-6632.1992.tb25978.x |
0.47 |
|
| 1992 |
Morton B, Ripley TL, Whittington MA, Butterworth AR, Little HJ. Evidence that changes in hippocampal excitability in vitro are caused by withdrawal from chronic in vivo ethanol administration. Alcohol and Alcoholism (Oxford, Oxfordshire). 27: 71-9. PMID 1316122 DOI: 10.1093/Oxfordjournals.Alcalc.A045196 |
0.713 |
|
| 1991 |
Whittington MA, Little HJ. Nitrendipine, given during drinking, decreases the electrophysiological changes in the isolated hippocampal slice, seen during ethanol withdrawal. British Journal of Pharmacology. 103: 1677-84. PMID 1933131 DOI: 10.1111/J.1476-5381.1991.Tb09846.X |
0.74 |
|
| 1991 |
Whittington MA, Dolin SJ, Patch TL, Siarey RJ, Butterworth AR, Little HJ. Chronic dihydropyridine treatment can reverse the behavioural consequences of and prevent adaptations to, chronic ethanol treatment. British Journal of Pharmacology. 103: 1669-76. PMID 1834295 DOI: 10.1111/J.1476-5381.1991.Tb09845.X |
0.716 |
|
| 1991 |
Whittington MA, Little HJ. A calcium channel antagonist stereoselectively decreases ethanol withdrawal hyperexcitability but not that due to bicuculline, in hippocampal slices. British Journal of Pharmacology. 103: 1313-20. PMID 1832063 DOI: 10.1111/J.1476-5381.1991.Tb09786.X |
0.726 |
|
| 1991 |
Dolin SJ, Patch TL, Rabbani M, Taberner PV, Little HJ. Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. Neuropharmacology. 30: 217-24. PMID 1712926 DOI: 10.1016/0028-3908(91)90148-5 |
0.349 |
|
| 1991 |
Little HJ. The benzodiazepines: anxiolytic and withdrawal effects. Neuropeptides. 19: 11-4. PMID 1679209 DOI: 10.1016/0143-4179(91)90077-V |
0.349 |
|
| 1991 |
Little HJ. Mechanisms that may underlie the behavioural effects of ethanol. Progress in Neurobiology. 36: 171-94. PMID 1673253 DOI: 10.1016/0301-0082(91)90029-Z |
0.497 |
|
| 1991 |
Little HJ. The role of neuronal calcium channels in dependence on ethanol and other sedatives/hypnotics. Pharmacology & Therapeutics. 50: 347-65. PMID 1661423 DOI: 10.1016/0163-7258(91)90050-V |
0.543 |
|
| 1990 |
Whittington MA, Little HJ. Patterns of changes in field potentials in the isolated hippocampal slice on withdrawal from chronic ethanol treatment of mice in vivo. Brain Research. 523: 237-44. PMID 2400909 DOI: 10.1016/0006-8993(90)91492-Y |
0.704 |
|
| 1990 |
Green AR, Davies EM, Little HJ, Whittington MA, Cross AJ. Action of chlormethiazole in a model of ethanol withdrawal. Psychopharmacology. 102: 239-42. PMID 2177205 DOI: 10.1007/Bf02245928 |
0.688 |
|
| 1990 |
Dolin SJ, Patch TL, Rabbani M, Siarey RJ, Bowhay AR, Little HJ. Nitrendipine decreases benzodiazepine withdrawal seizures but not the development of benzodiazepine tolerance or withdrawal signs. British Journal of Pharmacology. 101: 691-7. PMID 1963805 |
0.383 |
|
| 1990 |
Littleton JM, Little HJ, Whittington MA. Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644. Psychopharmacology. 100: 387-92. PMID 1690434 DOI: 10.1007/Bf02244612 |
0.707 |
|
| 1989 |
Dolin SJ, Little HJ. Are changes in neuronal calcium channels involved in ethanol tolerance? The Journal of Pharmacology and Experimental Therapeutics. 250: 985-91. PMID 2570870 |
0.62 |
|
| 1989 |
Dolin SJ, Little HJ. Effects of "nitrendipine" on nitrous oxide anesthesia, tolerance, and physical dependence. Anesthesiology. 70: 91-7. PMID 2521437 |
0.3 |
|
| 1989 |
Little HJ, Dolin SJ, Whittington MA. Possible role of calcium channels in ethanol tolerance and dependence Annals of the New York Academy of Sciences. 560: 465-466. |
0.681 |
|
| 1988 |
Dolin SJ, Hunter AB, Halsey MJ, Little HJ. Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine. European Journal of Pharmacology. 152: 19-27. PMID 2463174 DOI: 10.1016/0014-2999(88)90831-X |
0.386 |
|
| 1988 |
Dolin SJ, Halsey MJ, Little HJ. Effects of the calcium channel activator Bay K 8644 on general anaesthetic potency in mice. British Journal of Pharmacology. 94: 413-22. PMID 2456117 |
0.45 |
|
| 1987 |
Dolin S, Little H, Hudspith M, Pagonis C, Littleton J. Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence. Neuropharmacology. 26: 275-9. PMID 2438583 DOI: 10.1016/0028-3908(87)90220-6 |
0.452 |
|
| 1986 |
Little HJ, Dolin SJ, Halsey MJ. Calcium channel antagonists decrease the ethanol withdrawal syndrome. Life Sciences. 39: 2059-65. PMID 3784769 |
0.492 |
|
| 1986 |
Dolin SJ, Little HJ. Augmentation by calcium channel antagonists of general anaesthetic potency in mice. British Journal of Pharmacology. 88: 909-14. PMID 2943355 |
0.456 |
|
| 1985 |
Little HJ, Taylor SC, Nutt DJ, Cowen PJ. The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats. European Journal of Pharmacology. 107: 375-7. PMID 3920059 DOI: 10.1016/0014-2999(85)90265-1 |
0.443 |
|
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