Hilary Little - Publications


102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Rose AK, Shaw SG, Prendergast MA, Little HJ. The importance of glucocorticoids in alcohol dependence and neurotoxicity. Alcoholism, Clinical and Experimental Research. 34: 2011-8. PMID 21087289 DOI: 10.1111/j.1530-0277.2010.01298.x  1
2008 Brooks SP, Croft AP, Norman G, Shaw SG, Little HJ. Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. Neuroscience. 157: 376-84. PMID 18835336 DOI: 10.1016/j.neuroscience.2008.09.010  1
2008 Jacquot C, Croft AP, Prendergast MA, Mulholland P, Shaw SG, Little HJ. Effects of the glucocorticoid antagonist, mifepristone, on the consequences of withdrawal from long term alcohol consumption. Alcoholism, Clinical and Experimental Research. 32: 2107-16. PMID 18828802 DOI: 10.1111/j.1530-0277.2008.00799.x  1
2008 Little HJ, Croft AP, O'Callaghan MJ, Brooks SP, Wang G, Shaw SG. Selective increases in regional brain glucocorticoid: a novel effect of chronic alcohol. Neuroscience. 156: 1017-27. PMID 18801418 DOI: 10.1016/j.neuroscience.2008.08.029  1
2008 Croft AP, O'Callaghan MJ, Shaw SG, Connolly G, Jacquot C, Little HJ. Effects of minor laboratory procedures, adrenalectomy, social defeat or acute alcohol on regional brain concentrations of corticosterone. Brain Research. 1238: 12-22. PMID 18755165 DOI: 10.1016/j.brainres.2008.08.009  1
2008 Little HJ, McKinzie DL, Setnik B, Shram MJ, Sellers EM. Pharmacotherapy of alcohol dependence: Improving translation from the bench to the clinic Animal and Translational Models For Cns Drug Discovery. 3: 91-178. DOI: 10.1016/B978-0-12-373861-5.00025-4  1
2007 Prendergast MA, Little HJ. Adolescence, glucocorticoids and alcohol. Pharmacology, Biochemistry, and Behavior. 86: 234-45. PMID 16930684 DOI: 10.1016/j.pbb.2006.07.008  1
2007 Little HJ. Introduction to special issue of Alcohol and Alcoholism on alcohol and nicotine Alcohol and Alcoholism. 42: 165-166. DOI: 10.1093/alcalc/agm018  1
2006 Mulholland PJ, Self RL, Hensley AK, Little HJ, Littleton JM, Prendergast MA. A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis. Brain Research. 1082: 165-72. PMID 16510135 DOI: 10.1016/j.brainres.2006.01.069  1
2005 O'Callaghan MJ, Croft AP, Jacquot C, Little HJ. The hypothalamopituitary-adrenal axis and alcohol preference. Brain Research Bulletin. 68: 171-8. PMID 16325017 DOI: 10.1016/j.brainresbull.2005.08.006  1
2005 Croft AP, Brooks SP, Cole J, Little HJ. Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist. Psychopharmacology. 183: 163-70. PMID 16205917 DOI: 10.1007/s00213-005-0165-6  1
2005 Mulholland PJ, Self RL, Stepanyan TD, Little HJ, Littleton JM, Prendergast MA. Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro. Neuroscience. 135: 1129-39. PMID 16165302 DOI: 10.1016/j.neuroscience.2005.06.077  1
2005 Mulholland PJ, Self RL, Harris BR, Little HJ, Littleton JM, Prendergast MA. Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures. Alcoholism, Clinical and Experimental Research. 29: 871-81. PMID 15897733 DOI: 10.1097/01.ALC.0000163509.27577.DA  1
2005 Little HJ, Stephens DN, Ripley TL, Borlikova G, Duka T, Schubert M, Albrecht D, Becker HC, Lopez MF, Weiss F, Drummond C, Peoples M, Cunningham C. Alcohol withdrawal and conditioning. Alcoholism, Clinical and Experimental Research. 29: 453-64. PMID 15770122 DOI: 10.1097/01.ALC.0000156737.56425.E3  1
2005 Henderson G, Morton J, Little H. Drug abuse: From gene through cell to behaviour Current Opinion in Pharmacology. 5: 1-3. DOI: 10.1016/j.coph.2004.11.002  1
2004 Clark A, Little HJ. Interactions between low concentrations of ethanol and nicotine on firing rate of ventral tegmental dopamine neurones. Drug and Alcohol Dependence. 75: 199-206. PMID 15276226 DOI: 10.1016/j.drugalcdep.2004.03.001  1
2004 Brooks SP, Hennebry G, Croft AP, Thomas A, Little HJ. Effects of corticosterone on place conditioning to ethanol. Psychopharmacology. 174: 291-9. PMID 14767631 DOI: 10.1007/s00213-003-1745-y  1
2004 Little HJ. Alcohol is a drug; a cautionary note on its use as a drug solvent. Psychopharmacology. 171: 234-5. PMID 12961059 DOI: 10.1007/s00213-003-1580-1  1
2003 Diana M, Brodie M, Muntoni A, Puddu MC, Pillolla G, Steffensen S, Spiga S, Little HJ. Enduring effects of chronic ethanol in the CNS: basis for alcoholism. Alcoholism, Clinical and Experimental Research. 27: 354-61. PMID 12605085 DOI: 10.1097/01.ALC.0000057121.36127.19  1
2003 Little HJ. Comment on the paper by Horowski and Dorow. Psychopharmacology. 165: 320. PMID 12451440 DOI: 10.1007/s00213-002-1290-0  1
2002 Littleton J, Little H. Interactions between alcohol and nicotine dependence: a summary of potential mechanisms and implications for treatment. Alcoholism, Clinical and Experimental Research. 26: 1922-4. PMID 12500121 DOI: 10.1097/01.ALC.0000040941.36050.A7  1
2002 Norman G, Brooks SP, Hennebry GM, Eacott MJ, Little HJ. Nimodipine prevents scopolamine-induced impairments in object recognition. Journal of Psychopharmacology (Oxford, England). 16: 153-61. PMID 12095074  1
2002 Brooks SP, Hennebry G, McAlpin GP, Norman G, Little HJ. Nimodipine prevents the effects of ethanol in tests of memory. Neuropharmacology. 42: 577-85. PMID 11955528 DOI: 10.1016/S0028-3908(02)00006-0  1
2002 O'Callaghan MJ, Croft AP, Watson WP, Brooks SP, Little HJ. Low alcohol preference among the "high alcohol preference" C57/BL10 mice; factors affecting such preference. Pharmacology, Biochemistry, and Behavior. 72: 475-81. PMID 11900822 DOI: 10.1016/S0091-3057(02)00717-7  1
2002 Watson WP, Little HJ. Selectivity of the protective effects of dihydropyridine calcium channel antagonists against the ethanol withdrawal syndrome. Brain Research. 930: 111-22. PMID 11879801 DOI: 10.1016/S0006-8993(02)02236-9  1
2002 O'Callaghan MJ, Croft AP, Little HJ. Effects of intraperitoneal injections of saline on the alcohol and sucrose consumption of C57/BL10 mice. Psychopharmacology. 160: 206-12. PMID 11875639 DOI: 10.1007/s00213-001-0968-z  1
2001 Bailey CP, O'Callaghan MJ, Croft AP, Manley SJ, Little HJ. Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption. Neuropharmacology. 41: 989-99. PMID 11747903 DOI: 10.1016/S0028-3908(01)00146-0  1
2001 Clark A, Lindgren S, Brooks SP, Watson WP, Little HJ. Chronic infusion of nicotine can increase operant self-administration of alcohol. Neuropharmacology. 41: 108-17. PMID 11445191 DOI: 10.1016/S0028-3908(01)00037-5  1
2001 Holt JD, Watson WP, Little HJ. Studies on a model of long term alcohol drinking. Behavioural Brain Research. 123: 193-200. PMID 11399331 DOI: 10.1016/S0166-4328(01)00206-6  1
2000 Little HJ. Behavioral mechanisms underlying the link between smoking and drinking. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 24: 215-24. PMID 15986716  1
2000 Little HJ. Alcohol as a stimulant drug. Addiction (Abingdon, England). 95: 1751-3. PMID 11177488 DOI: 10.1080/09652140020011045  1
2000 Bailey CP, Andrews N, McKnight AT, Hughes J, Little HJ. Prolonged changes in neurochemistry of dopamine neurones after chronic ethanol consumption. Pharmacology, Biochemistry, and Behavior. 66: 153-61. PMID 10837855 DOI: 10.1016/S0091-3057(00)00230-6  1
2000 Little HJ, Clark A, Watson WP. Investigations into pharmacological antagonism of general anaesthesia. British Journal of Pharmacology. 129: 1755-63. PMID 10780983 DOI: 10.1038/sj.bjp.0703262  1
2000 Smith JW, Little HJ. Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance. Brain Research. 863: 9-19. PMID 10773188 DOI: 10.1016/S0006-8993(00)02064-3  1
2000 Cole JC, Littleton JM, Little HJ. Acamprosate, but not naltrexone, inhibits conditioned abstinence behaviour associated with repeated ethanol administration and exposure to a plus-maze. Psychopharmacology. 147: 403-11. PMID 10672634  1
1999 Wilson J, Woodruff GN, Little HJ. Concurrent chronic administration of a CCK(B) antagonist can decrease tolerance to the ataxic effects of ethanol. Addiction Biology. 4: 35-45. PMID 20575768 DOI: 10.1080/13556219971821  1
1999 Smith JW, Watson WP, Stephens DN, Little HJ. The calcium channel antagonist, nimodipine, decreases operant self-administration of low concentrations of ethanol. Behavioural Pharmacology. 10: 793-802. PMID 10780295  1
1999 Little HJ. The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanol. Pharmacology & Therapeutics. 84: 333-53. PMID 10665833 DOI: 10.1016/S0163-7258(99)00040-6  1
1999 Little HJ, O'Callaghan MJ, Butterworth AR, Wilson J, Cole J, Watson WP. Low alcohol preference among the "high alcohol preference" C57 strain of mice; preference increased by saline injections. Psychopharmacology. 147: 182-9. PMID 10591886  1
1999 Cho K, Little HJ. Effects of corticosterone on excitatory amino acid responses in dopamine-sensitive neurons in the ventral tegmental area. Neuroscience. 88: 837-45. PMID 10363821 DOI: 10.1016/S0306-4522(98)00264-4  1
1999 Watson WP, Little HJ. Prolonged effects of chronic ethanol treatment on responses to repeated nicotine administration: interactions with environmental cues. Neuropharmacology. 38: 587-95. PMID 10221762 DOI: 10.1016/S0028-3908(98)00220-2  1
1999 Cole JC, Littleton JM, Little HJ. Effects of repeated ethanol administration in the plus maze; a simple model for conditioned abstinence behaviour. Psychopharmacology. 142: 270-9. PMID 10208319 DOI: 10.1007/s002130050889  1
1999 Watson WP, Little HJ. Correlation between increases in dihydropyridine binding in vivo and behavioural signs of ethanol withdrawal in mice. Alcohol and Alcoholism (Oxford, Oxfordshire). 34: 35-42. PMID 10075399 DOI: 10.1093/alcalc/34.1.35  1
1999 Rabbani M, Little HJ. Increases in neuronal Ca2+ flux after withdrawal from chronic barbiturate treatment. European Journal of Pharmacology. 364: 221-7. PMID 9932727 DOI: 10.1016/S0014-2999(98)00781-X  1
1998 Watson WP, Homewood N, Little HJ. Differing acute interactions of ethanol with two structurally related dihydropyridines, nitrendipine and felodipine. Brain Research Bulletin. 47: 337-43. PMID 9886785 DOI: 10.1016/S0361-9230(98)00085-9  1
1998 Bailey CP, Manley SJ, Watson WP, Wonnacott S, Molleman A, Little HJ. Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability. Brain Research. 803: 144-52. PMID 9729345 DOI: 10.1016/S0006-8993(98)00654-4  1
1998 Wilson J, Watson WP, Little HJ. CCK(B) antagonists protect against anxiety-related behaviour produced by ethanol withdrawal, measured using the elevated plus maze. Psychopharmacology. 137: 120-31. PMID 9629998 DOI: 10.1007/s002130050601  1
1998 Wilson J, Little HJ. CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome. Pharmacology, Biochemistry, and Behavior. 59: 967-73. PMID 9586857 DOI: 10.1016/S0091-3057(97)00536-4  1
1998 Bailey CP, Molleman A, Little HJ. Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption. British Journal of Pharmacology. 123: 215-22. PMID 9489608 DOI: 10.1038/sj.bjp.0701596  1
1997 Watson WP, Robinson E, Little HJ. The novel anticonvulsant, gabapentin, protects against both convulsant and anxiogenic aspects of the ethanol withdrawal syndrome. Neuropharmacology. 36: 1369-75. PMID 9423924 DOI: 10.1016/S0028-3908(97)00118-4  1
1997 Manley SJ, Little HJ. Enhancement of amphetamine- and cocaine-induced locomotor activity after chronic ethanol administration. The Journal of Pharmacology and Experimental Therapeutics. 281: 1330-9. PMID 9190869  1
1996 Ripley TL, Whittington MA, Butterworth AR, Little HJ. Ethanol withdrawal hyperexcitability in vivo and in isolated mouse hippocampal slices. Alcohol and Alcoholism (Oxford, Oxfordshire). 31: 347-57. PMID 8879281  1
1996 Little HJ. How has molecular pharmacology contributed to our understanding of the mechanism(s) of general anesthesia? Pharmacology & Therapeutics. 69: 37-58. PMID 8857302 DOI: 10.1016/0163-7258(95)02030-6  1
1995 Ripley TL, Little HJ. Ethanol withdrawal hyperexcitability in vitro is selectively decreased by a competitive NMDA receptor antagonist. Brain Research. 699: 1-11. PMID 8616595 DOI: 10.1016/0006-8993(95)00445-V  1
1995 Watson WP, Little HJ. Identification of distinct components, with different time courses, of the changes in response to convulsive stimuli during ethanol withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 272: 876-84. PMID 7853206  1
1995 Ripley TL, Little HJ. Effects on ethanol withdrawal hyperexcitability of chronic treatment with a competitive N-methyl-D-aspartate receptor antagonist. The Journal of Pharmacology and Experimental Therapeutics. 272: 112-8. PMID 7815323  1
1995 Mead AJ, Little HJ. Do GABAB receptors have a role in causing behavioural hyperexcitability, both during ethanol withdrawal and in naive mice? Psychopharmacology. 117: 232-9. PMID 7753972 DOI: 10.1007/BF02245192  1
1995 Whittington MA, Lambert JD, Little HJ. Increased NMDA receptor and calcium channel activity underlying ethanol withdrawal hyperexcitability. Alcohol and Alcoholism (Oxford, Oxfordshire). 30: 105-14. PMID 7748267  1
1995 Rabbani M, Wright EJ, Little HJ. Tolerance to competitive NMDA antagonists, but no crosstolerance with barbiturates. Pharmacology, Biochemistry, and Behavior. 50: 9-15. PMID 7700959 DOI: 10.1016/0091-3057(94)00215-5  1
1995 Little HJ. The role of calcium channels in drug dependence. Drug and Alcohol Dependence. 38: 173-94. PMID 7671768 DOI: 10.1016/0376-8716(95)01121-E  1
1995 Ripley TL, Little HJ. Nitrendipine prevents the decrease caused by chronic ethanol intake in the maintenance of tetanic long-term potentiation. Experimental Brain Research. 103: 1-8. PMID 7615026 DOI: 10.1007/BF00241959  1
1995 Molleman A, Little HJ. Increases in non-N-methyl-D-aspartate glutamatergic transmission, but no change in gamma-aminobutyric acidB transmission, in CA1 neurons during withdrawal from in vivo chronic ethanol treatment. The Journal of Pharmacology and Experimental Therapeutics. 274: 1035-41. PMID 7562466  1
1994 Rabbani M, Brown J, Butterworth AR, Little HJ. Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal. Pharmacology, Biochemistry, and Behavior. 47: 675-80. PMID 8208788 DOI: 10.1016/0091-3057(94)90173-2  1
1994 Rabbani M, Wright J, Butterworth AR, Zhou Q, Little HJ. Possible involvement of NMDA receptor-mediated transmission in barbiturate physical dependence. British Journal of Pharmacology. 111: 89-96. PMID 7912157  1
1994 Littleton J, Little H. Current concepts of ethanol dependence. Addiction (Abingdon, England). 89: 1397-412. PMID 7841849 DOI: 10.1111/j.1360-0443.1994.tb03736.x  1
1994 Watson WP, Little HJ. Interactions between diltiazem and ethanol: differences from those seen with dihydropyridine calcium channel antagonists. Psychopharmacology. 114: 329-36. PMID 7838926 DOI: 10.1007/BF02244856  1
1994 Watson WP, Little HJ. Effects of diltiazem in convulsive states differ from those previously reported for dihydropyridine calcium channel antagonists. Psychopharmacology. 114: 321-8. PMID 7530854 DOI: 10.1007/BF02244855  1
1994 Watson WP, Misra A, Cross AJ, Green AR, Little HJ. The differential effects of felodipine and nitrendipine on cerebral dihydropyridine binding ex vivo and the ethanol withdrawal syndrome in mice. British Journal of Pharmacology. 112: 1017-24. PMID 7524989  1
1993 Whittington MA, Lambert JD, Little HJ. Increases in synaptic activation of calcium current as a mechanism for generation of ethanol withdrawal seizures. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 391-4. PMID 7748328  1
1993 Little HJ, Dolin SJ, Whittington MA. Calcium channel antagonists prevent adaptive responses to ethanol. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 263-7. PMID 7748308  1
1993 Whittington MA, Little HJ. Changes in voltage-operated calcium channels modify ethanol withdrawal hyperexcitability in mouse hippocampal slices. Experimental Physiology. 78: 347-70. PMID 7687135  1
1992 Whittington MA, Butterworth AR, Dolin SJ, Patch TL, Little HJ. The effects of chronic treatment with the dihydropyridine, Bay K 8644, on hyperexcitability due to ethanol withdrawal, in vivo and in vitro. British Journal of Pharmacology. 105: 285-92. PMID 1373096  1
1992 Whittington MA, Little HJ, Lambert JD. Changes in intrinsic inhibition in isolated hippocampal slices during ethanol withdrawal; lack of correlation with withdrawal hyperexcitability. British Journal of Pharmacology. 107: 521-7. PMID 1330182  1
1992 Little HJ, Andreasen M, Lambert JD. Chronic treatment with a benzodiazepine agonist in vivo increases the actions of the benzodiazepine partial inverse agonist, FG7142, on the hippocampal slice in vitro. Brain Research. 573: 243-50. PMID 1324078 DOI: 10.1016/0006-8993(92)90769-6  1
1992 Littleton J, Little H, Laverty R. Role of neuronal calcium channels in ethanol dependence: from cell cultures to the intact animal. Annals of the New York Academy of Sciences. 654: 324-34. PMID 1321573  1
1992 Morton B, Ripley TL, Whittington MA, Butterworth AR, Little HJ. Evidence that changes in hippocampal excitability in vitro are caused by withdrawal from chronic in vivo ethanol administration. Alcohol and Alcoholism (Oxford, Oxfordshire). 27: 71-9. PMID 1316122  1
1991 Whittington MA, Little HJ. Nitrendipine, given during drinking, decreases the electrophysiological changes in the isolated hippocampal slice, seen during ethanol withdrawal. British Journal of Pharmacology. 103: 1677-84. PMID 1933131  1
1991 Whittington MA, Dolin SJ, Patch TL, Siarey RJ, Butterworth AR, Little HJ. Chronic dihydropyridine treatment can reverse the behavioural consequences of and prevent adaptations to, chronic ethanol treatment. British Journal of Pharmacology. 103: 1669-76. PMID 1834295  1
1991 Whittington MA, Little HJ. A calcium channel antagonist stereoselectively decreases ethanol withdrawal hyperexcitability but not that due to bicuculline, in hippocampal slices. British Journal of Pharmacology. 103: 1313-20. PMID 1832063  1
1991 Dolin SJ, Patch TL, Rabbani M, Taberner PV, Little HJ. Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. Neuropharmacology. 30: 217-24. PMID 1712926 DOI: 10.1016/0028-3908(91)90148-5  1
1991 Little HJ. The benzodiazepines: anxiolytic and withdrawal effects. Neuropeptides. 19: 11-4. PMID 1679209 DOI: 10.1016/0143-4179(91)90077-V  1
1991 Little HJ. Mechanisms that may underlie the behavioural effects of ethanol. Progress in Neurobiology. 36: 171-94. PMID 1673253 DOI: 10.1016/0301-0082(91)90029-Z  1
1991 Little HJ. The role of neuronal calcium channels in dependence on ethanol and other sedatives/hypnotics. Pharmacology & Therapeutics. 50: 347-65. PMID 1661423 DOI: 10.1016/0163-7258(91)90050-V  1
1990 Whittington MA, Little HJ. Patterns of changes in field potentials in the isolated hippocampal slice on withdrawal from chronic ethanol treatment of mice in vivo. Brain Research. 523: 237-44. PMID 2400909 DOI: 10.1016/0006-8993(90)91492-Y  1
1990 Green AR, Davies EM, Little HJ, Whittington MA, Cross AJ. Action of chlormethiazole in a model of ethanol withdrawal. Psychopharmacology. 102: 239-42. PMID 2177205 DOI: 10.1007/BF02245928  1
1990 Stanford SC, Gettins D, Little HJ. Adverse effects on rat cardiac function ex vivo after repeated administration of the benzodiazepine partial inverse agonist, FG7142. British Journal of Pharmacology. 99: 441-4. PMID 2158841  1
1990 Dolin SJ, Patch TL, Rabbani M, Siarey RJ, Bowhay AR, Little HJ. Nitrendipine decreases benzodiazepine withdrawal seizures but not the development of benzodiazepine tolerance or withdrawal signs. British Journal of Pharmacology. 101: 691-7. PMID 1963805  1
1990 Appleyard ME, Taylor SC, Little HJ. Acetylcholinesterase activity in regions of mouse brain following acute and chronic treatment with a benzodiazepine inverse agonist. British Journal of Pharmacology. 101: 599-604. PMID 1963800  1
1990 Littleton JM, Little HJ, Whittington MA. Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644. Psychopharmacology. 100: 387-92. PMID 1690434 DOI: 10.1007/BF02244612  1
1989 Halsey MJ, Little HJ, Wardley-Smith B. Systemically administered glycine protects against strychnine convulsions, but not the behavioural effects of high pressure, in mice. The Journal of Physiology. 408: 431-41. PMID 2778736  1
1989 Dolin SJ, Little HJ. Are changes in neuronal calcium channels involved in ethanol tolerance? The Journal of Pharmacology and Experimental Therapeutics. 250: 985-91. PMID 2570870  1
1989 Dolin SJ, Little HJ. Effects of "nitrendipine" on nitrous oxide anesthesia, tolerance, and physical dependence. Anesthesiology. 70: 91-7. PMID 2521437  1
1989 Little HJ, Dolin SJ, Whittington MA. Possible role of calcium channels in ethanol tolerance and dependence Annals of the New York Academy of Sciences. 560: 465-466.  1
1988 Little HJ. Chronic benzodiazepine treatment increases the effects of inverse agonists. Advances in Biochemical Psychopharmacology. 45: 307-23. PMID 2902745  1
1988 Little HJ, Gale R, Sellars N, Nutt DJ, Taylor SC. Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142. Neuropharmacology. 27: 383-9. PMID 2901672 DOI: 10.1016/0028-3908(88)90147-5  1
1988 Taylor SC, Johnston AL, Wilks LJ, Nicholass JM, File SE, Little HJ. Kindling with the beta-carboline FG7142 suggests separation between changes in seizure threshold and anxiety-related behaviour. Neuropsychobiology. 19: 195-201. PMID 2854610 DOI: 10.1159/000118460  1
1988 Nutt DJ, Taylor SC, Little HJ, Standing BL, Gale RG. Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice. Psychopharmacology. 95: 407-12. PMID 2842814 DOI: 10.1007/BF00181957  1
1988 Dolin SJ, Hunter AB, Halsey MJ, Little HJ. Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine. European Journal of Pharmacology. 152: 19-27. PMID 2463174 DOI: 10.1016/0014-2999(88)90831-X  1
1988 Dolin SJ, Halsey MJ, Little HJ. Effects of the calcium channel activator Bay K 8644 on general anaesthetic potency in mice. British Journal of Pharmacology. 94: 413-22. PMID 2456117  1
1988 Littleton JM, Little HJ. Dihydropyridine-sensitive Ca2+ channels in brain are involved in the central nervous system hyperexcitability associated with alcohol withdrawal states Annals of the New York Academy of Sciences. 522: 199-202.  1
1986 Little HJ, Dolin SJ, Halsey MJ. Calcium channel antagonists decrease the ethanol withdrawal syndrome. Life Sciences. 39: 2059-65. PMID 3784769  0.72
1986 Dolin SJ, Little HJ. Augmentation by calcium channel antagonists of general anaesthetic potency in mice. British Journal of Pharmacology. 88: 909-14. PMID 2943355  0.72
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