John Gordon Ralph Jefferys, PhD - Publications

Pharmacology University of Oxford, Oxford, United Kingdom 
Neuronal networks, electrophysiology, epilepsy, prions, oscillations

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Morris G, Jiruska P, Jefferys JG, Powell AD. A New Approach of Modified Submerged Patch Clamp Recording Reveals Interneuronal Dynamics during Epileptiform Oscillations. Frontiers in Neuroscience. 10: 519. PMID 27881950 DOI: 10.3389/Fnins.2016.00519  0.828
2016 Mei H, Thackston K, Bercich R, Jefferys J, Irazoqui P. Cavity Resonator Wireless Power Transfer System for Freely Moving Animal Experiments. Ieee Transactions On Bio-Medical Engineering. PMID 27295647 DOI: 10.1109/Tbme.2016.2576469  0.552
2016 Mellström B, Kastanauskaite A, Knafo S, Gonzalez P, Dopazo XM, Ruiz-Nuño A, Jefferys JG, Zhuo M, Bliss TV, Naranjo JR, DeFelipe J. Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice. Molecular Brain. 9: 22. PMID 26928278 DOI: 10.1186/S13041-016-0204-8  0.381
2015 Avoli M, Crunelli V, Jefferys J. Preface for Methods and Models in Epilepsy Research. Journal of Neuroscience Methods. PMID 26642969 DOI: 10.1016/J.Jneumeth.2015.11.016  0.521
2015 Avoli M, Jefferys JG. Models of drug-induced epileptiform synchronization in vitro. Journal of Neuroscience Methods. PMID 26484784 DOI: 10.1016/J.Jneumeth.2015.10.006  0.617
2015 Jefferys J, Steinhäuser C, Bedner P. Chemically-induced TLE models: Topical application. Journal of Neuroscience Methods. PMID 25960204 DOI: 10.1016/J.Jneumeth.2015.04.011  0.344
2015 Rombo DM, Newton K, Nissen W, Badurek S, Horn JM, Minichiello L, Jefferys JG, Sebastiao AM, Lamsa KP. Synaptic mechanisms of adenosine A2A receptor-mediated hyperexcitability in the hippocampus. Hippocampus. 25: 566-80. PMID 25402014 DOI: 10.1002/Hipo.22392  0.435
2015 Janca R, Jezdik P, Cmejla R, Tomasek M, Worrell GA, Stead M, Wagenaar J, Jefferys JG, Krsek P, Komarek V, Jiruska P, Marusic P. Detection of interictal epileptiform discharges using signal envelope distribution modelling: application to epileptic and non-epileptic intracranial recordings. Brain Topography. 28: 172-83. PMID 24970691 DOI: 10.1007/S10548-014-0379-1  0.686
2015 Ferecskó AS, Jiruska P, Foss L, Powell AD, Chang WC, Sik A, Jefferys JG. Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy. Brain Structure & Function. 220: 1013-29. PMID 24442865 DOI: 10.1007/S00429-013-0697-1  0.808
2015 Marusic P, Janca R, Krsek P, Jezdik P, Cmejla R, Tomasek M, Jefferys JG, Komarek V, Jiruska P. 26. Functional organization of the irritative zone in neocortical epilepsy Clinical Neurophysiology. 126: e38. DOI: 10.1016/J.Clinph.2014.10.185  0.675
2014 Jefferys JG. How does epileptic activity spread? Epilepsy Currents / American Epilepsy Society. 14: 289-90. PMID 25346643 DOI: 10.5698/1535-7597-14.5.289  0.325
2014 Jefferys JG. Do seizures in the pilocarpine model start in the hippocampal formation? Epilepsy Currents / American Epilepsy Society. 14: 206-7. PMID 25170320 DOI: 10.5698/1535-7597-14.4.206  0.395
2014 Jiruska P, de Curtis M, Jefferys JG. Modern concepts of focal epileptic networks. International Review of Neurobiology. 114: 1-7. PMID 25078496 DOI: 10.1016/B978-0-12-418693-4.00001-7  0.688
2014 Jefferys JG. Are changes in synaptic function that underlie hyperexcitability responsible for seizure activity? Advances in Experimental Medicine and Biology. 813: 185-94. PMID 25012377 DOI: 10.1007/978-94-017-8914-1_15  0.521
2014 Powell AD, Saintot PP, Gill KK, Bharathan A, Buck SC, Morris G, Jiruska P, Jefferys JG. Reduced gamma oscillations in a mouse model of intellectual disability: a role for impaired repetitive neurotransmission? Plos One. 9: e95871. PMID 24800744 DOI: 10.1371/Journal.Pone.0095871  0.781
2014 Nieto-Rostro M, Sandhu G, Bauer CS, Jiruska P, Jefferys JG, Dolphin AC. Altered expression of the voltage-gated calcium channel subunit α₂δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain. Neuroscience. 283: 124-37. PMID 24641886 DOI: 10.1016/J.Neuroscience.2014.03.013  0.701
2014 Mellström B, Sahún I, Ruiz-Nuño A, Murtra P, Gomez-Villafuertes R, Savignac M, Oliveros JC, Gonzalez P, Kastanauskaite A, Knafo S, Zhuo M, Higuera-Matas A, Errington ML, Maldonado R, DeFelipe J, ... Jefferys JG, et al. DREAM controls the on/off switch of specific activity-dependent transcription pathways. Molecular and Cellular Biology. 34: 877-87. PMID 24366545 DOI: 10.1128/Mcb.00360-13  0.329
2014 Pietersen AN, Ward PD, Hagger-Vaughan N, Wiggins J, Jefferys JG, Vreugdenhil M. Transition between fast and slow gamma modes in rat hippocampus area CA1 in vitro is modulated by slow CA3 gamma oscillations. The Journal of Physiology. 592: 605-20. PMID 24277864 DOI: 10.1113/Jphysiol.2013.263889  0.731
2013 Mormann F, Jefferys JG. Neuronal firing in human epileptic cortex: the ins and outs of synchrony during seizures. Epilepsy Currents / American Epilepsy Society. 13: 100-2. PMID 23646019 DOI: 10.5698/1535-7597-13.2.100  0.409
2013 Jiruska P, Shtaya AB, Bodansky DM, Chang WC, Gray WP, Jefferys JG. Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy. Neurobiology of Disease. 54: 492-8. PMID 23439313 DOI: 10.1016/J.Nbd.2013.02.001  0.807
2013 Jiruska P, de Curtis M, Jefferys JG, Schevon CA, Schiff SJ, Schindler K. Synchronization and desynchronization in epilepsy: controversies and hypotheses. The Journal of Physiology. 591: 787-97. PMID 23184516 DOI: 10.1113/Jphysiol.2012.239590  0.741
2013 Jefferys J. Cellular Mechanisms Of Epilepsy Journal of Neurology, Neurosurgery, and Psychiatry. 84. DOI: 10.1136/Jnnp-2013-306103.12  0.436
2012 Jefferys JG, Menendez de la Prida L, Wendling F, Bragin A, Avoli M, Timofeev I, Lopes da Silva FH. Mechanisms of physiological and epileptic HFO generation. Progress in Neurobiology. 98: 250-64. PMID 22420980 DOI: 10.1016/J.Pneurobio.2012.02.005  0.632
2012 Zijlmans M, Jiruska P, Zelmann R, Leijten FS, Jefferys JG, Gotman J. High-frequency oscillations as a new biomarker in epilepsy. Annals of Neurology. 71: 169-78. PMID 22367988 DOI: 10.1002/Ana.22548  0.737
2012 Powell AD, Gill KK, Saintot PP, Jiruska P, Chelly J, Billuart P, Jefferys JG. Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation. The Journal of Physiology. 590: 763-76. PMID 22124149 DOI: 10.1113/Jphysiol.2011.219907  0.794
2011 Richardson MP, Jefferys JG. Introduction--Epilepsy Research UK Workshop 2010 on "Preictal Phenomena". Epilepsy Research. 97: 229-30. PMID 22094447 DOI: 10.1016/J.Eplepsyres.2011.10.027  0.307
2011 Jiruska P, Marusic P, Jefferys JG, Krsek P, Cmejla R, Sebronova V, Komarek V. Sturge-Weber syndrome: a favourable surgical outcome in a case with contralateral seizure onset and myoclonic-astatic seizures. Epileptic Disorders : International Epilepsy Journal With Videotape. 13: 76-81. PMID 21393095 DOI: 10.1684/Epd.2011.0407  0.7
2011 Ratté S, Vreugdenhil M, Boult JK, Patel A, Asante EA, Collinge J, Jefferys JG. Threshold for epileptiform activity is elevated in prion knockout mice. Neuroscience. 179: 56-61. PMID 21277354 DOI: 10.1016/J.Neuroscience.2011.01.053  0.753
2011 Lu CB, Jefferys JG, Toescu EC, Vreugdenhil M. In vitro hippocampal gamma oscillation power as an index of in vivo CA3 gamma oscillation strength and spatial reference memory. Neurobiology of Learning and Memory. 95: 221-30. PMID 21093596 DOI: 10.1016/J.Nlm.2010.11.008  0.722
2010 Jefferys JG. Advances in understanding basic mechanisms of epilepsy and seizures. Seizure. 19: 638-46. PMID 21095139 DOI: 10.1016/J.Seizure.2010.10.026  0.38
2010 Jiruska P, Powell AD, Deans JK, Jefferys JG. Effects of direct brain stimulation depend on seizure dynamics. Epilepsia. 51: 93-7. PMID 20618410 DOI: 10.1111/J.1528-1167.2010.02619.X  0.798
2010 Jiruska P, Csicsvari J, Powell AD, Fox JE, Chang WC, Vreugdenhil M, Li X, Palus M, Bujan AF, Dearden RW, Jefferys JG. High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5690-701. PMID 20410121 DOI: 10.1523/Jneurosci.0535-10.2010  0.833
2010 Jiruska P, Finnerty GT, Powell AD, Lofti N, Cmejla R, Jefferys JG. Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy. Brain : a Journal of Neurology. 133: 1380-90. PMID 20400525 DOI: 10.1093/Brain/Awq070  0.818
2010 Oke OO, Magony A, Anver H, Ward PD, Jiruska P, Jefferys JG, Vreugdenhil M. High-frequency gamma oscillations coexist with low-frequency gamma oscillations in the rat visual cortex in vitro. The European Journal of Neuroscience. 31: 1435-45. PMID 20384769 DOI: 10.1111/J.1460-9568.2010.07171.X  0.804
2010 Jiruska P, Powell AD, Chang WC, Jefferys JG. Electrographic high-frequency activity and epilepsy. Epilepsy Research. 89: 60-5. PMID 20031373 DOI: 10.1016/J.Eplepsyres.2009.11.008  0.806
2009 Jiruska P, Cmejla R, Powell AD, Chang WC, Vreugdenhil M, Jefferys JG. Reference noise method of removing powerline noise from recorded signals. Journal of Neuroscience Methods. 184: 110-4. PMID 19595705 DOI: 10.1016/J.Jneumeth.2009.07.003  0.75
2009 Pietersen AN, Patel N, Jefferys JG, Vreugdenhil M. Comparison between spontaneous and kainate-induced gamma oscillations in the mouse hippocampus in vitro. The European Journal of Neuroscience. 29: 2145-56. PMID 19490088 DOI: 10.1111/J.1460-9568.2009.06771.X  0.745
2009 Khelfaoui M, Pavlowsky A, Powell AD, Valnegri P, Cheong KW, Blandin Y, Passafaro M, Jefferys JG, Chelly J, Billuart P. Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation. Human Molecular Genetics. 18: 2575-83. PMID 19401298 DOI: 10.1093/Hmg/Ddp189  0.802
2008 Jiruska P, Tomasek M, Netuka D, Otahal J, Jefferys JG, Li X, Marusic P. Clinical impact of a high-frequency seizure onset zone in a case of bitemporal epilepsy. Epileptic Disorders : International Epilepsy Journal With Videotape. 10: 231-8. PMID 18782695 DOI: 10.1684/Epd.2008.0207  0.722
2008 Li X, Jefferys JG, Fox J, Yao X. Neuronal population oscillations of rat hippocampus during epileptic seizures. Neural Networks : the Official Journal of the International Neural Network Society. 21: 1105-11. PMID 18657392 DOI: 10.1016/J.Neunet.2008.06.002  0.61
2008 Ratté S, Prescott SA, Collinge J, Jefferys JG. Hippocampal bursts caused by changes in NMDA receptor-dependent excitation in a mouse model of variant CJD. Neurobiology of Disease. 32: 96-104. PMID 18638557 DOI: 10.1016/J.Nbd.2008.06.007  0.518
2008 Powell AD, Toescu EC, Collinge J, Jefferys JG. Alterations in Ca2+-buffering in prion-null mice: association with reduced afterhyperpolarizations in CA1 hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3877-86. PMID 18400886 DOI: 10.1523/Jneurosci.0675-08.2008  0.803
2007 Nateri AS, Raivich G, Gebhardt C, Da Costa C, Naumann H, Vreugdenhil M, Makwana M, Brandner S, Adams RH, Jefferys JG, Kann O, Behrens A. ERK activation causes epilepsy by stimulating NMDA receptor activity. The Embo Journal. 26: 4891-901. PMID 17972914 DOI: 10.1038/Sj.Emboj.7601911  0.725
2007 Li X, Cui D, Jiruska P, Fox JE, Yao X, Jefferys JG. Synchronization measurement of multiple neuronal populations. Journal of Neurophysiology. 98: 3341-8. PMID 17913983 DOI: 10.1152/Jn.00977.2007  0.75
2007 Deans JK, Powell AD, Jefferys JG. Sensitivity of coherent oscillations in rat hippocampus to AC electric fields. The Journal of Physiology. 583: 555-65. PMID 17599962 DOI: 10.1113/Jphysiol.2007.137711  0.791
2007 Mallucci GR, White MD, Farmer M, Dickinson A, Khatun H, Powell AD, Brandner S, Jefferys JG, Collinge J. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron. 53: 325-35. PMID 17270731 DOI: 10.1016/J.Neuron.2007.01.005  0.784
2007 Fox JE, Bikson M, Jefferys JG. The effect of neuronal population size on the development of epileptiform discharges in the low calcium model of epilepsy. Neuroscience Letters. 411: 158-61. PMID 17097230 DOI: 10.1016/J.Neulet.2006.10.021  0.675
2007 Li X, Yao X, Fox J, Jefferys JG. Interaction dynamics of neuronal oscillations analysed using wavelet transforms. Journal of Neuroscience Methods. 160: 178-85. PMID 16973218 DOI: 10.1016/J.Jneumeth.2006.08.006  0.491
2007 Fox J, Bikson M, Jefferys J. Depolarisation block underlies the interruption of synchronised neuronal discharges in the low calcium model of epilepsy Clinical Neurophysiology. 118: e143. DOI: 10.1016/J.Clinph.2006.07.188  0.57
2005 Bihi RI, Jefferys JG, Vreugdenhil M. The role of extracellular potassium in the epileptogenic transformation of recurrent GABAergic inhibition. Epilepsia. 46: 64-71. PMID 15987256 DOI: 10.1111/J.1528-1167.2005.01011.X  0.757
2005 Merrill DR, Bikson M, Jefferys JG. Electrical stimulation of excitable tissue: design of efficacious and safe protocols. Journal of Neuroscience Methods. 141: 171-98. PMID 15661300 DOI: 10.1016/J.Jneumeth.2004.10.020  0.467
2005 Vreugdenhil M, Bracci E, Jefferys JG. Layer-specific pyramidal cell oscillations evoked by tetanic stimulation in the rat hippocampal area CA1 in vitro and in vivo. The Journal of Physiology. 562: 149-64. PMID 15528242 DOI: 10.1113/Jphysiol.2004.075390  0.85
2004 Asante EA, Li YG, Gowland I, Jefferys JG, Collinge J. Pathogenic human prion protein rescues PrP null phenotype in transgenic mice. Neuroscience Letters. 360: 33-6. PMID 15082172 DOI: 10.1016/J.Neulet.2004.01.049  0.503
2004 Fox JE, Bikson M, Jefferys JG. Tissue resistance changes and the profile of synchronized neuronal activity during ictal events in the low-calcium model of epilepsy. Journal of Neurophysiology. 92: 181-8. PMID 14999050 DOI: 10.1152/Jn.00123.2004  0.685
2004 Bikson M, Inoue M, Akiyama H, Deans JK, Fox JE, Miyakawa H, Jefferys JG. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. The Journal of Physiology. 557: 175-90. PMID 14978199 DOI: 10.1113/Jphysiol.2003.055772  0.736
2003 Jefferys JG, Deans J, Bikson M, Fox J. Effects of weak electric fields on the activity of neurons and neuronal networks. Radiation Protection Dosimetry. 106: 321-3. PMID 14690274 DOI: 10.1093/Oxfordjournals.Rpd.A006367  0.729
2003 Jefferys JG. Models and mechanisms of experimental epilepsies. Epilepsia. 44: 44-50. PMID 14641560 DOI: 10.1111/J.0013-9580.2003.12004.X  0.456
2003 Bikson M, Hahn PJ, Fox JE, Jefferys JG. Depolarization block of neurons during maintenance of electrographic seizures. Journal of Neurophysiology. 90: 2402-8. PMID 12801897 DOI: 10.1152/Jn.00467.2003  0.706
2003 Bikson M, Fox JE, Jefferys JG. Neuronal aggregate formation underlies spatiotemporal dynamics of nonsynaptic seizure initiation. Journal of Neurophysiology. 89: 2330-3. PMID 12686586 DOI: 10.1152/Jn.00764.2002  0.704
2003 Vreugdenhil M, Jefferys JG, Celio MR, Schwaller B. Parvalbumin-deficiency facilitates repetitive IPSCs and gamma oscillations in the hippocampus. Journal of Neurophysiology. 89: 1414-22. PMID 12626620 DOI: 10.1152/Jn.00576.2002  0.752
2002 Finnerty GT, Jefferys JG. Investigation of the neuronal aggregate generating seizures in the rat tetanus toxin model of epilepsy. Journal of Neurophysiology. 88: 2919-27. PMID 12466418 DOI: 10.1152/jn.00211.2002  0.766
2002 Bikson M, Id Bihi R, Vreugdenhil M, Köhling R, Fox JE, Jefferys JG. Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro. Neuroscience. 115: 251-61. PMID 12401338 DOI: 10.1016/S0306-4522(02)00320-2  0.828
2002 Vreugdenhil M, Hack SP, Draguhn A, Jefferys JG. Tetanus toxin induces long-term changes in excitation and inhibition in the rat hippocampal CA1 area. Neuroscience. 114: 983-94. PMID 12379253 DOI: 10.1016/S0306-4522(02)00212-9  0.847
2002 Saunders RD, Jefferys JG. Weak electric field interactions in the central nervous system. Health Physics. 83: 366-75. PMID 12199550 DOI: 10.1097/00004032-200209000-00006  0.327
2002 Doheny HC, Whittington MA, Jefferys JG, Patsalos PN. A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy. British Journal of Pharmacology. 135: 1425-34. PMID 11906955 DOI: 10.1038/Sj.Bjp.0704606  0.807
2002 Mallucci GR, Ratté S, Asante EA, Linehan J, Gowland I, Jefferys JG, Collinge J. Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. The Embo Journal. 21: 202-10. PMID 11823413 DOI: 10.1093/Emboj/21.3.202  0.552
2001 Finnerty GT, Whittington MA, Jefferys JG. Altered dentate filtering during the transition to seizure in the rat tetanus toxin model of epilepsy. Journal of Neurophysiology. 86: 2748-53. PMID 11731534 DOI: 10.1152/Jn.2001.86.6.2748  0.816
2001 Köhling R, Gladwell SJ, Bracci E, Vreugdenhil M, Jefferys JG. Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling. Neuroscience. 105: 579-87. PMID 11516825 DOI: 10.1016/S0306-4522(01)00222-6  0.84
2001 Bracci E, Vreugdenhil M, Hack SP, Jefferys JG. Dynamic modulation of excitation and inhibition during stimulation at gamma and beta frequencies in the CA1 hippocampal region. Journal of Neurophysiology. 85: 2412-22. PMID 11387387 DOI: 10.1152/Jn.2001.85.6.2412  0.845
2001 Gladwell SJ, Jefferys JG. Second messenger modulation of electrotonic coupling between region CA3 pyramidal cell axons in the rat hippocampus. Neuroscience Letters. 300: 1-4. PMID 11172925 DOI: 10.1016/S0304-3940(01)01530-0  0.804
2001 Empson RM, Jefferys JG. Ca(2+) entry through L-type Ca(2+) channels helps terminate epileptiform activity by activation of a Ca(2+) dependent afterhyperpolarisation in hippocampal CA3. Neuroscience. 102: 297-306. PMID 11166116 DOI: 10.1016/S0306-4522(00)00494-2  0.77
2000 Köhling R, Vreugdenhil M, Bracci E, Jefferys JG. Ictal epileptiform activity is facilitated by hippocampal GABAA receptor-mediated oscillations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6820-9. PMID 10995826 DOI: 10.1523/Jneurosci.20-18-06820.2000  0.846
2000 Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K. Functional phenotype in transgenic mice expressing mutant human presenilin-1. Neurobiology of Disease. 7: 119-26. PMID 10783295 DOI: 10.1006/Nbdi.1999.0276  0.789
2000 Finnerty GT, Jefferys JG. 9-16 Hz oscillation precedes secondary generalization of seizures in the rat tetanus toxin model of epilepsy. Journal of Neurophysiology. 83: 2217-26. PMID 10758130 DOI: 10.1152/Jn.2000.83.4.2217  0.787
1999 Borck C, Jefferys JG. Seizure-like events in disinhibited ventral slices of adult rat hippocampus. Journal of Neurophysiology. 82: 2130-42. PMID 10561393 DOI: 10.1152/Jn.1999.82.5.2130  0.738
1999 Barrow PA, Holmgren CD, Tapper AJ, Jefferys JG. Intrinsic physiological and morphological properties of principal cells of the hippocampus and neocortex in hamsters infected with scrapie. Neurobiology of Disease. 6: 406-23. PMID 10527807 DOI: 10.1006/Nbdi.1999.0255  0.456
1999 Traub RD, Jefferys JG, Whittington MA. Functionally relevant and functionally disruptive (epileptic) synchronized oscillations in brain slices. Advances in Neurology. 79: 709-24. PMID 10514857  0.788
1999 Bracci E, Vreugdenhil M, Hack SP, Jefferys JG. On the synchronizing mechanisms of tetanically induced hippocampal oscillations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8104-13. PMID 10479710 DOI: 10.1523/Jneurosci.19-18-08104.1999  0.839
1999 Traub RD, Schmitz D, Jefferys JG, Draguhn A. High-frequency population oscillations are predicted to occur in hippocampal pyramidal neuronal networks interconnected by axoaxonal gap junctions. Neuroscience. 92: 407-26. PMID 10408594 DOI: 10.1016/S0306-4522(98)00755-6  0.706
1999 Jefferys JG. Hippocampal sclerosis and temporal lobe epilepsy: cause or consequence? Brain : a Journal of Neurology. 122: 1007-8. PMID 10356054 DOI: 10.1093/Brain/122.6.1007  0.38
1999 Doheny HC, Ratnaraj N, Whittington MA, Jefferys JG, Patsalos PN. Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat. Epilepsy Research. 34: 161-8. PMID 10210031 DOI: 10.1016/S0920-1211(98)00104-1  0.76
1999 Walker MC, Perry H, Scaravilli F, Patsalos PN, Shorvon SD, Jefferys JG. Halothane as a neuroprotectant during constant stimulation of the perforant path. Epilepsia. 40: 359-64. PMID 10080519 DOI: 10.1111/J.1528-1157.1999.Tb00718.X  0.326
1999 Traub RD, Whittington MA, Buhl EH, Jefferys JG, Faulkner HJ. On the mechanism of the gamma --> beta frequency shift in neuronal oscillations induced in rat hippocampal slices by tetanic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1088-105. PMID 9920671 DOI: 10.1523/Jneurosci.19-03-01088.1999  0.766
1998 Jefferys JG, Traub RD. Electrophysiological substrates for focal epilepsies. Progress in Brain Research. 116: 351-8. PMID 9932387 DOI: 10.1016/S0079-6123(08)60447-1  0.689
1998 Fox JE, Jefferys JG. Frequency and synchrony of tetanically-induced, gamma-frequency population discharges in the rat hippocampal slice: the effect of diazepam and propofol. Neuroscience Letters. 257: 101-4. PMID 9865937 DOI: 10.1016/S0304-3940(98)00812-X  0.562
1998 Jefferys JG, Traub RD. 'Dormant' inhibitory neurons: do they exist and what is their functional impact? Epilepsy Research. 32: 104-13. PMID 9761313 DOI: 10.1016/S0920-1211(98)00044-8  0.67
1998 Draguhn A, Traub RD, Schmitz D, Jefferys JG. Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro. Nature. 394: 189-92. PMID 9671303 DOI: 10.1038/28184  0.718
1998 Stanford IM, Traub RD, Jefferys JG. Limbic gamma rhythms. II. Synaptic and intrinsic mechanisms underlying spike doublets in oscillating subicular neurons. Journal of Neurophysiology. 80: 162-71. PMID 9658038 DOI: 10.1152/Jn.1998.80.1.162  0.837
1998 Colling SB, Stanford IM, Traub RD, Jefferys JG. Limbic gamma rhythms. I. Phase-locked oscillations in hippocampal CA1 and subiculum. Journal of Neurophysiology. 80: 155-61. PMID 9658037 DOI: 10.1152/Jn.1998.80.1.155  0.811
1998 Whittington MA, Traub RD, Faulkner HJ, Jefferys JG, Chettiar K. Morphine disrupts long-range synchrony of gamma oscillations in hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 95: 5807-11. PMID 9576966 DOI: 10.1073/Pnas.95.10.5807  0.756
1998 Jefferys JG. Mechanisms and experimental models of seizure generation. Current Opinion in Neurology. 11: 123-7. PMID 9551292 DOI: 10.1097/00019052-199804000-00008  0.383
1997 Whittington MA, Traub RD, Faulkner HJ, Stanford IM, Jefferys JG. Recurrent excitatory postsynaptic potentials induced by synchronized fast cortical oscillations. Proceedings of the National Academy of Sciences of the United States of America. 94: 12198-203. PMID 9342386 DOI: 10.1073/Pnas.94.22.12198  0.832
1997 Whittington MA, Stanford IM, Colling SB, Jefferys JG, Traub RD. Spatiotemporal patterns of gamma frequency oscillations tetanically induced in the rat hippocampal slice. The Journal of Physiology. 502: 591-607. PMID 9279811 DOI: 10.1111/J.1469-7793.1997.591Bj.X  0.828
1997 Colling SB, Khana M, Collinge J, Jefferys JG. Mossy fibre reorganization in the hippocampus of prion protein null mice. Brain Research. 755: 28-35. PMID 9163538 DOI: 10.1016/S0006-8993(97)00087-5  0.814
1997 Traub RD, Jefferys JG, Whittington MA. Simulation of gamma rhythms in networks of interneurons and pyramidal cells. Journal of Computational Neuroscience. 4: 141-50. PMID 9154520 DOI: 10.1023/A:1008839312043  0.777
1996 Colling SB, Man WD, Draguhn A, Jefferys JG. Dendritic shrinkage and dye-coupling between rat hippocampal CA1 pyramidal cells in the tetanus toxin model of epilepsy. Brain Research. 741: 38-43. PMID 9001702 DOI: 10.1016/S0006-8993(96)00884-0  0.82
1996 Jefferys JG, Whittington MA. Review of the role of inhibitory neurons in chronic epileptic foci induced by intracerebral tetanus toxin. Epilepsy Research. 26: 59-66. PMID 8985687 DOI: 10.1016/S0920-1211(96)00040-X  0.678
1996 Whittington MA, Jefferys JG, Traub RD. Effects of intravenous anaesthetic agents on fast inhibitory oscillations in the rat hippocampus in vitro. British Journal of Pharmacology. 118: 1977-86. PMID 8864532 DOI: 10.1111/J.1476-5381.1996.Tb15633.X  0.743
1996 Traub RD, Whittington MA, Stanford IM, Jefferys JG. A mechanism for generation of long-range synchronous fast oscillations in the cortex. Nature. 383: 621-4. PMID 8857537 DOI: 10.1038/383621A0  0.829
1996 Traub RD, Borck C, Colling SB, Jefferys JG. On the structure of ictal events in vitro. Epilepsia. 37: 879-91. PMID 8814102 DOI: 10.1111/J.1528-1157.1996.Tb00042.X  0.828
1996 Traub RD, Whittington MA, Colling SB, Buzsáki G, Jefferys JG. Analysis of gamma rhythms in the rat hippocampus in vitro and in vivo. The Journal of Physiology. 493: 471-84. PMID 8782110 DOI: 10.1113/Jphysiol.1996.Sp021397  0.842
1996 Colling SB, Collinge J, Jefferys JG. Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents. Neuroscience Letters. 209: 49-52. PMID 8734907 DOI: 10.1016/0304-3940(96)12596-9  0.809
1996 Jefferys JG, Traub RD, Whittington MA. Neuronal networks for induced '40 Hz' rhythms. Trends in Neurosciences. 19: 202-8. PMID 8723208 DOI: 10.1016/S0166-2236(96)10023-0  0.76
1995 Traub RD, Colling SB, Jefferys JG. Cellular mechanisms of 4-aminopyridine-induced synchronized after-discharges in the rat hippocampal slice. The Journal of Physiology. 489: 127-40. PMID 8583397 DOI: 10.1113/Jphysiol.1995.Sp021036  0.842
1995 Whittington MA, Traub RD, Jefferys JG. Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation. Nature. 373: 612-5. PMID 7854418 DOI: 10.1038/373612A0  0.776
1995 Whittington MA, Sidle KC, Gowland I, Meads J, Hill AF, Palmer MS, Jefferys JG, Collinge J. Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein. Nature Genetics. 9: 197-201. PMID 7719349 DOI: 10.1038/Ng0295-197  0.646
1995 Jefferys JG, Borck C, Mellanby J. Chronic focal epilepsy induced by intracerebral tetanus toxin. Italian Journal of Neurological Sciences. 16: 27-32. PMID 7642348 DOI: 10.1007/BF02229071  0.713
1995 Walker MC, Galley PT, Errington ML, Shorvon SD, Jefferys JG. Ascorbate and glutamate release in the rat hippocampus after perforant path stimulation: a "dialysis electrode" study. Journal of Neurochemistry. 65: 725-31. PMID 7616229 DOI: 10.1046/J.1471-4159.1995.65020725.X  0.592
1995 Jefferys JG. Nonsynaptic modulation of neuronal activity in the brain: electric currents and extracellular ions. Physiological Reviews. 75: 689-723. PMID 7480159 DOI: 10.1152/Physrev.1995.75.4.689  0.35
1995 Whittington MA, Traub RD, Jefferys JG. Erosion of inhibition contributes to the progression of low magnesium bursts in rat hippocampal slices. The Journal of Physiology. 486: 723-34. PMID 7473233 DOI: 10.1113/Jphysiol.1995.Sp020848  0.761
1994 Jefferys JG, Empson RM, Whittington MA, Prusiner SB. Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones. Neurobiology of Disease. 1: 25-30. PMID 9216983 DOI: 10.1006/Nbdi.1994.0004  0.81
1994 Collinge J, Whittington MA, Sidle KC, Smith CJ, Palmer MS, Clarke AR, Jefferys JG. Prion protein is necessary for normal synaptic function. Nature. 370: 295-7. PMID 8035877 DOI: 10.1038/370295A0  0.694
1994 Traub RD, Jefferys JG, Whittington MA. Enhanced NMDA conductance can account for epileptiform activity induced by low Mg2+ in the rat hippocampal slice. The Journal of Physiology. 478: 379-93. PMID 7965853 DOI: 10.1113/Jphysiol.1994.Sp020259  0.773
1994 Traub RD, Jefferys JG, Miles R, Whittington MA, Tóth K. A branching dendritic model of a rodent CA3 pyramidal neurone. The Journal of Physiology. 481: 79-95. PMID 7853251 DOI: 10.1113/Jphysiol.1994.Sp020420  0.783
1994 Traub RD, Jefferys JG. Simulations of epileptiform activity in the hippocampal CA3 region in vitro. Hippocampus. 4: 281-5. PMID 7842050 DOI: 10.1002/Hipo.450040310  0.653
1994 Traub RD, Jefferys JG. Are there unifying principles underlying the generation of epileptic afterdischarges in vitro? Progress in Brain Research. 102: 383-94. PMID 7800828 DOI: 10.1016/S0079-6123(08)60554-3  0.748
1994 Whittington MA, Jefferys JG. Epileptic activity outlasts disinhibition after intrahippocampal tetanus toxin in the rat. The Journal of Physiology. 481: 593-604. PMID 7707228 DOI: 10.1113/Jphysiol.1994.Sp020466  0.69
1994 Jefferys JG. Experimental neurobiology of epilepsies. Current Opinion in Neurology. 7: 113-22. PMID 7517278 DOI: 10.1097/00019052-199404000-00007  0.504
1993 Watts AE, Jefferys JG. Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices. British Journal of Pharmacology. 108: 819-23. PMID 8467367 DOI: 10.1111/J.1476-5381.1993.Tb12884.X  0.776
1993 Traub RD, Miles R, Jefferys JG. Synaptic and intrinsic conductances shape picrotoxin-induced synchronized after-discharges in the guinea-pig hippocampal slice. The Journal of Physiology. 461: 525-47. PMID 8350274 DOI: 10.1113/Jphysiol.1993.Sp019527  0.707
1993 Williams SF, Colling SB, Whittington MA, Jefferys JG. Epileptic focus induced by intrahippocampal cholera toxin in rat: time course and properties in vivo and in vitro. Epilepsy Research. 16: 137-46. PMID 8269912 DOI: 10.1016/0920-1211(93)90028-6  0.848
1993 Finnerty GT, Jefferys JG. Functional connectivity from CA3 to the ipsilateral and contralateral CA1 in the rat dorsal hippocampus. Neuroscience. 56: 101-8. PMID 8232909 DOI: 10.1016/0306-4522(93)90566-X  0.747
1993 Traub RD, Jefferys JG, Miles R. Analysis of the propagation of disinhibition-induced after-discharges along the guinea-pig hippocampal slice in vitro. The Journal of Physiology. 472: 267-87. PMID 8145144 DOI: 10.1113/Jphysiol.1993.Sp019946  0.701
1993 Empson RM, Amitai Y, Jefferys JG, Gutnick MJ. Injection of tetanus toxin into the neocortex elicits persistent epileptiform activity but only transient impairment of GABA release. Neuroscience. 57: 235-9. PMID 8115035 DOI: 10.1016/0306-4522(93)90058-N  0.821
1993 Watts AE, Whittington MA, Jefferys JG. Epileptic focus induced in rat by intrahippocampal cholera toxin: neuronal properties in vitro. Neuroscience. 55: 45-56. PMID 8102480 DOI: 10.1016/0306-4522(93)90453-M  0.834
1993 Empson RM, Jefferys JG. Synaptic inhibition in primary and secondary chronic epileptic foci induced by intrahippocampal tetanus toxin in the rat. The Journal of Physiology. 465: 595-614. PMID 7901403 DOI: 10.1113/Jphysiol.1993.Sp019695  0.807
1992 Jordan SJ, Jefferys JG. Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin. Epilepsy Research. 11: 119-29. PMID 1618177 DOI: 10.1016/0920-1211(92)90046-V  0.692
1992 Jefferys JG, Evans BJ, Hughes SA, Williams SF. Neuropathology of the chronic epileptic syndrome induced by intrahippocampal tetanus toxin in rat: preservation of pyramidal cells and incidence of dark cells. Neuropathology and Applied Neurobiology. 18: 53-70. PMID 1579200  0.351
1992 Najlerahim A, Williams SF, Pearson RC, Jefferys JG. Increased expression of GAD mRNA during the chronic epileptic syndrome due to intrahippocampal tetanus toxin. Experimental Brain Research. 90: 332-42. PMID 1397147 DOI: 10.1007/Bf00227246  0.424
1991 Jefferys JG, Mitchell P, O'Hara L, Tiley C, Hardy J, Jordan SJ, Lynch M, Wadsworth J. Ex vivo release of GABA from tetanus toxin-induced chronic epileptic foci decreased during the active seizure phase. Neurochemistry International. 18: 373-9. PMID 20504714 DOI: 10.1016/0197-0186(91)90169-E  0.617
1991 Brener K, Amitai Y, Jefferys JG, Gutnick MJ. Chronic epileptic foci in neocortex: in vivo and in vitro effects of tetanus toxin. The European Journal of Neuroscience. 3: 47-54. PMID 12106268 DOI: 10.1111/J.1460-9568.1991.Tb00810.X  0.697
1990 Ives AE, Jefferys JG. Synchronization of epileptiform bursts induced by 4-aminopyridine in the in vitro hippocampal slice preparation. Neuroscience Letters. 112: 239-45. PMID 2359522 DOI: 10.1016/0304-3940(90)90210-Z  0.476
1990 Jefferys JG, Empson RM. Development of chronic secondary epileptic foci following intrahippocampal injection of tetanus toxin in the rat. Experimental Physiology. 75: 733-6. PMID 2245026 DOI: 10.1113/Expphysiol.1990.Sp003455  0.77
1990 Francis PT, Lowe SL, Bowen DM, Jefferys JG. Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats. Epilepsia. 31: 697-701. PMID 1700950 DOI: 10.1111/J.1528-1157.1990.Tb05508.X  0.308
1989 Jefferys JG. Chronic epileptic foci in vitro in hippocampal slices from rats with the tetanus toxin epileptic syndrome. Journal of Neurophysiology. 62: 458-68. PMID 2504891 DOI: 10.1152/Jn.1989.62.2.458  0.37
1987 Jefferys JG, Williams SF. Physiological and behavioural consequences of seizures induced in the rat by intrahippocampal tetanus toxin. Brain : a Journal of Neurology. 110: 517-32. PMID 3567534 DOI: 10.1093/Brain/110.2.517  0.429
1985 Brace HM, Jefferys JG, Mellanby J. Long-term changes in hippocampal physiology and learning ability of rats after intrahippocampal tetanus toxin. The Journal of Physiology. 368: 343-57. PMID 4078743 DOI: 10.1113/jphysiol.1985.sp015861  0.356
1984 Bliss TV, Errington ML, Jefferys JG, Hjorth-Simonsen A, Laurberg S. Structure and function of aberrant perforant path synapses in the hippocampus of neonatally X-irradiated rats. Neuroscience Letters. 50: 1-6. PMID 6493616 DOI: 10.1016/0304-3940(84)90452-X  0.369
1984 Haas HL, Jefferys JG. Low-calcium field burst discharges of CA1 pyramidal neurones in rat hippocampal slices. The Journal of Physiology. 354: 185-201. PMID 6481633 DOI: 10.1113/jphysiol.1984.sp015371  0.582
1984 Haas HL, Jefferys JG, Slater NT, Carpenter DO. Modulation of low calcium induced field bursts in the hippocampus by monoamines and cholinomimetics. PflüGers Archiv : European Journal of Physiology. 400: 28-33. PMID 6324067 DOI: 10.1007/BF00670532  0.473
1982 Jefferys JG, Haas HL. Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission. Nature. 300: 448-50. PMID 6292731  0.542
1981 Thomas PK, Jefferys JG, Smith IS, Loulakakis D. Spinal somatosensory evoked potentials in hereditary spastic paraplegia. Journal of Neurology, Neurosurgery, and Psychiatry. 44: 243-6. PMID 7229648  0.379
1981 Thomas PK, Jefferys JG, Sharma AK, Bajada S. Nerve conduction velocity in experimental diabetes in the rat and rabbit. Journal of Neurology, Neurosurgery, and Psychiatry. 44: 233-8. PMID 7229647  0.31
1980 Brismar T, Jefferys JG. Convulsants (benzylpenicillin and pentylenetetrazol) on potential clamped myelinated axons from the rat. Acta Physiologica Scandinavica. 110: 145-8. PMID 7211400 DOI: 10.1111/j.1748-1716.1980.tb06644.x  0.498
1980 Jefferys JG, Brismar T. Analysis of peripheral nerve function in streptozotocin diabetic rats. Journal of the Neurological Sciences. 48: 435-44. PMID 6255106 DOI: 10.1016/0022-510X(80)90114-8  0.473
1978 Jefferys JG, Palmano KP, Sharma AK, Thomas PK. Influence of dietary myoinositol on nerve conduction and inositol phospholipids in normal and diabetic rats. Journal of Neurology, Neurosurgery, and Psychiatry. 41: 333-9. PMID 650240 DOI: 10.1136/Jnnp.41.4.333  0.416
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