Lindsay B. Hough - Publications

Affiliations: 
Neuropharmacology and Neuroscience Albany Medical College, Albany, NY, United States 
Area:
Pain research

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hough LB, Nalwalk JW, Ding X, Sheer N. Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26109562 DOI: 10.1124/dmd.115.065490  0.36
2015 Hough LB, Nalwalk JW, Yang W, Ding X. Neuronal cytochrome P450 activity and opioid analgesia: relevant sites and mechanisms. Brain Research. 1616: 10-8. PMID 25935691 DOI: 10.1016/j.brainres.2015.04.045  0.36
2014 Hough LB, Nalwalk JW, Cleary RA, Phillips JG, Fang C, Yang W, Ding X. Deficits in neuronal cytochrome P450 activity attenuate opioid analgesia but not opioid side effects. European Journal of Pharmacology. 740: 255-62. PMID 25062792 DOI: 10.1016/j.ejphar.2014.07.028  0.36
2014 Hough LB, Nalwalk JW, Yang W, Ding X. Significance of neuronal cytochrome P450 activity in opioid-mediated stress-induced analgesia. Brain Research. 1578: 30-7. PMID 25020125 DOI: 10.1016/j.brainres.2014.07.007  0.36
2013 Li L, Jia K, Zhou X, McCallum SE, Hough LB, Ding X. Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse. The Journal of Pharmacology and Experimental Therapeutics. 347: 746-54. PMID 24045421 DOI: 10.1124/jpet.113.208256  0.36
2013 Hoerbelt P, Nalwalk JW, Phillips JG, Wentland MP, Shan Z, Hough LB. Antinociceptive activity of CC44, a biotinylated improgan congener. European Journal of Pharmacology. 714: 464-71. PMID 23834775 DOI: 10.1016/j.ejphar.2013.06.041  0.36
2013 Agarwal JJ, Zhu Y, Zhang QY, Mongin AA, Hough LB. TRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activity. Plos One. 8: e63028. PMID 23667566 DOI: 10.1371/journal.pone.0063028  0.36
2013 Conroy JL, Nalwalk JW, Phillips JG, Hough LB. CC12, a P450/epoxygenase inhibitor, acts in the rat rostral, ventromedial medulla to attenuate morphine antinociception. Brain Research. 1499: 1-11. PMID 23298831 DOI: 10.1016/j.brainres.2012.12.030  0.36
2012 Yang J, VanAlstine MA, Phillips JG, Wentland MP, Hough LB. Cytochrome P450 2C24: Expression, Tissue Distribution, High-Throughput Assay, and Pharmacological Inhibition. Acta Pharmaceutica Sinica. B. 2: 137-145. PMID 25068100 DOI: 10.1016/j.apsb.2012.02.003  0.36
2012 Phillips RS, Cleary DR, Nalwalk JW, Arttamangkul S, Hough LB, Heinricher MM. Pain-facilitating medullary neurons contribute to opioid-induced respiratory depression. Journal of Neurophysiology. 108: 2393-404. PMID 22956800 DOI: 10.1152/jn.00563.2012  0.36
2012 Fleck MW, Thomson JL, Hough LB. Histamine-gated ion channels in mammals? Biochemical Pharmacology. 83: 1127-35. PMID 22192818 DOI: 10.1016/j.bcp.2011.12.011  0.36
2011 Albrecht PJ, Nalwalk JW, Hough LB. Efficacy of improgan, a non-opioid analgesic, in neuropathic pain. Brain Research. 1424: 32-7. PMID 22015352 DOI: 10.1016/j.brainres.2011.10.002  0.36
2011 VanAlstine MA, Hough LB. Effects of acetylenic epoxygenase inhibitors on recombinant cytochrome p450s. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1221-6. PMID 21460231 DOI: 10.1124/dmd.110.037424  0.36
2011 Hough LB, Nalwalk JW, Yang J, Conroy JL, VanAlstine MA, Yang W, Gargano J, Shan Z, Zhang SZ, Wentland MP, Phillips JG, Knapp BI, Bidlack JM, Zuiderveld OP, Leurs R, et al. Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic. Pain. 152: 878-87. PMID 21316152 DOI: 10.1016/j.pain.2011.01.001  0.36
2011 Hough LB, Rice FL. H3 receptors and pain modulation: peripheral, spinal, and brain interactions. The Journal of Pharmacology and Experimental Therapeutics. 336: 30-7. PMID 20864501 DOI: 10.1124/jpet.110.171264  0.36
2010 Heinricher MM, Maire JJ, Lee D, Nalwalk JW, Hough LB. Physiological basis for inhibition of morphine and improgan antinociception by CC12, a P450 epoxygenase inhibitor. Journal of Neurophysiology. 104: 3222-30. PMID 20926616 DOI: 10.1152/jn.00681.2010  0.36
2010 Heinricher MM, Martenson ME, Nalwalk JW, Hough LB. Neural basis for improgan antinociception. Neuroscience. 169: 1414-20. PMID 20570607 DOI: 10.1016/j.neuroscience.2010.05.042  0.36
2010 Conroy JL, Fang C, Gu J, Zeitlin SO, Yang W, Yang J, VanAlstine MA, Nalwalk JW, Albrecht PJ, Mazurkiewicz JE, Snyder-Keller A, Shan Z, Zhang SZ, Wentland MP, Behr M, ... ... Hough LB, et al. Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling. Nature Neuroscience. 13: 284-6. PMID 20139973 DOI: 10.1038/nn.2497  0.36
2010 Stadel R, Carpenter AB, Nalwalk JW, de Esch IJ, Janssen E, Hough LB. Inhibition of brain [(3)H]cimetidine binding by improgan-like antinociceptive drugs. European Journal of Pharmacology. 632: 33-8. PMID 20138862 DOI: 10.1016/j.ejphar.2010.01.026  0.36
2009 Grimberg BT, Jaworska MM, Hough LB, Zimmerman PA, Phillips JG. Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials. Bioorganic & Medicinal Chemistry Letters. 19: 5452-7. PMID 19666223 DOI: 10.1016/j.bmcl.2009.07.095  0.36
2009 Hough LB, Svokos K, Nalwalk JW. Non-opioid antinociception produced by brain stem injections of improgan: significance of local, but not cross-regional, cannabinoid mechanisms. Brain Research. 1247: 62-70. PMID 18983834 DOI: 10.1016/j.brainres.2008.10.008  0.36
2008 Stadel R, Yang J, Nalwalk JW, Phillips JG, Hough LB. High-affinity binding of [3H]cimetidine to a heme-containing protein in rat brain. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 614-21. PMID 18094038 DOI: 10.1124/dmd.107.017889  0.36
2007 Hough LB, Menge WM, van de Stolpe AC, Nalwalk JW, Leurs R, de Esch IJ. Antinociceptive activity of furan-containing congeners of improgan and ranitidine. Bioorganic & Medicinal Chemistry Letters. 17: 5715-9. PMID 17766108 DOI: 10.1016/j.bmcl.2007.07.060  0.36
2007 Cannon KE, Leurs R, Hough LB. Activation of peripheral and spinal histamine H3 receptors inhibits formalin-induced inflammation and nociception, respectively. Pharmacology, Biochemistry, and Behavior. 88: 122-9. PMID 17719621 DOI: 10.1016/j.pbb.2007.07.014  0.36
2007 Gehani NC, Nalwalk JW, Razdan RK, Martin BR, Sun X, Wentland M, Abood ME, Hough LB. Significance of cannabinoid CB1 receptors in improgan antinociception. The Journal of Pain : Official Journal of the American Pain Society. 8: 850-60. PMID 17644043 DOI: 10.1016/j.jpain.2007.05.015  0.36
2007 Salussolia CL, Nalwalk JW, Hough LB. Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature. Brain Research. 1152: 42-8. PMID 17433267 DOI: 10.1016/j.brainres.2007.03.033  0.36
2007 Hough LB, Nalwalk JW, Phillips JG, Kern B, Shan Z, Wentland MP, de Esch IJ, Janssen E, Barr T, Stadel R. CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist. Neuropharmacology. 52: 1244-55. PMID 17336343 DOI: 10.1016/j.neuropharm.2007.01.004  0.36
2007 Cannon KE, Chazot PL, Hann V, Shenton F, Hough LB, Rice FL. Immunohistochemical localization of histamine H3 receptors in rodent skin, dorsal root ganglia, superior cervical ganglia, and spinal cord: potential antinociceptive targets. Pain. 129: 76-92. PMID 17134835 DOI: 10.1016/j.pain.2006.09.039  0.36
2006 Nalwalk JW, Svokos K, Hough LB. Cannabinoid-improgan cross-tolerance: Improgan is a cannabinomimetic analgesic lacking affinity at the cannabinoid CB1 receptor. European Journal of Pharmacology. 549: 79-83. PMID 16989809 DOI: 10.1016/j.ejphar.2006.08.035  0.36
2006 Hough LB, de Esch IJ, Janssen E, Phillips J, Svokos K, Kern B, Trachler J, Abood ME, Leurs R, Nalwalk JW. Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic. Neuropharmacology. 51: 447-56. PMID 16806300 DOI: 10.1016/j.neuropharm.2006.04.003  0.36
2006 Dai H, Zhang Z, Zhu Y, Shen Y, Hu W, Huang Y, Luo J, Timmerman H, Leurs R, Chen Z. Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways. Journal of Neurochemistry. 96: 1390-400. PMID 16478529 DOI: 10.1111/j.1471-4159.2005.03633.x  0.36
2005 Hough LB, Nalwalk JW, Lu Q, Shan Z, Svokos K, Wentland MP, Montero MJ. Antinociceptive, brain-penetrating derivatives related to improgan, a non-opioid analgesic. European Journal of Pharmacology. 522: 38-46. PMID 16216240 DOI: 10.1016/j.ejphar.2005.08.040  0.36
2005 Taraschenko OD, Barnes WG, Herrick-Davis K, Yokoyama Y, Boyd DL, Hough LB. Actions of tacrine and galanthamine on histamine-N-methyltransferase. Methods and Findings in Experimental and Clinical Pharmacology. 27: 161-5. PMID 15834447 DOI: 10.1358/mf.2005.27.3.890872  0.36
2005 Cannon KE, Hough LB. Inhibition of chemical and low-intensity mechanical nociception by activation of histamine H3 receptors. The Journal of Pain : Official Journal of the American Pain Society. 6: 193-200. PMID 15772913 DOI: 10.1016/j.jpain.2004.12.003  0.36
2005 Nalwalk JW, Svokos K, Leurs R, Hough LB. Absence of 5-HT3 and cholinergic mechanisms in improgan antinociception. Pharmacology, Biochemistry, and Behavior. 80: 505-10. PMID 15740793 DOI: 10.1016/j.pbb.2005.01.006  0.36
2004 Cannon KE, Fleck MW, Hough LB. Effects of cimetidine-like drugs on recombinant GABAA receptors. Life Sciences. 75: 2551-8. PMID 15363660 DOI: 10.1016/j.lfs.2004.05.020  0.36
2004 Nalwalk JW, Svokos K, Taraschenko O, Leurs R, Timmerman H, Hough LB. Activation of brain stem nuclei by improgan, a non-opioid analgesic. Brain Research. 1021: 248-55. PMID 15342273 DOI: 10.1016/j.brainres.2004.06.066  0.36
2004 Hough LB, Nalwalk JW, Svokos K, Leurs R, Timmermann H. Pain-relieving drugs and the brain histaminergic system: multiple analgesic mechanisms from histamine, improgan and cimetidine. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 53: S43-4. PMID 15054611 DOI: 10.1007/s00011-003-0320-7  0.36
2004 Barnes WG, Grinde E, Crawford DR, Herrick-Davis K, Hough LB. Characterization of a new mRNA species from the human histamine N-methyltransferase gene. Genomics. 83: 168-71. PMID 14667820 DOI: 10.1016/S0888-7543(03)00236-2  0.36
2004 Hough LB, Nalwalk JW, Menge W, Leurs R, Timmerman H. Improgan-like analgesics: A family of compounds derived from histamine antagonists Medicinal Chemistry Research. 13: 78-87. DOI: 10.1007/s00044-004-0012-z  0.36
2003 Cannon KE, Nalwalk JW, Stadel R, Ge P, Lawson D, Silos-Santiago I, Hough LB. Activation of spinal histamine H3 receptors inhibits mechanical nociception. European Journal of Pharmacology. 470: 139-47. PMID 12798951 DOI: 10.1016/S0014-2999(03)01737-0  0.36
2003 Izadi Mobarakeh J, Nalwalk JW, Watanabe T, Sakurada S, Hoffman M, Leurs R, Timmerman H, Silos-Santiago I, Yanai K, Hough LB. Improgan antinociception does not require neuronal histamine or histamine receptors. Brain Research. 974: 146-52. PMID 12742632 DOI: 10.1016/S0006-8993(03)02572-1  0.36
2002 Barnes WG, Hough LB. Membrane-bound histamine N-methyltransferase in mouse brain: possible role in the synaptic inactivation of neuronal histamine. Journal of Neurochemistry. 82: 1262-71. PMID 12358773 DOI: 10.1046/j.1471-4159.2002.01063.x  0.36
2002 Langlais PJ, McRee RC, Nalwalk JA, Hough LB. Depletion of brain histamine produces regionally selective protection against thiamine deficiency-induced lesions in the rat. Metabolic Brain Disease. 17: 199-210. PMID 12322789 DOI: 10.1023/A:1019930206196  0.36
2002 Hough LB, Nalwalk JW, Stadel R, Timmerman H, Leurs R, Paria BC, Wang X, Dey SK. Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors. The Journal of Pharmacology and Experimental Therapeutics. 303: 314-22. PMID 12235266 DOI: 10.1124/jpet.102.036251  0.36
2002 Strecker RE, Nalwalk J, Dauphin LJ, Thakkar MM, Chen Y, Ramesh V, Hough LB, McCarley RW. Extracellular histamine levels in the feline preoptic/anterior hypothalamic area during natural sleep-wakefulness and prolonged wakefulness: an in vivo microdialysis study. Neuroscience. 113: 663-70. PMID 12150786 DOI: 10.1016/S0306-4522(02)00158-6  0.36
2001 Svokos K, Nalwalk JW, Leurs R, Menge WM, Timmerman H, Hough LB. A role for spinal, but not supraspinal, alpha(2) adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic. Brain Research. 923: 12-9. PMID 11743967 DOI: 10.1016/S0006-8993(01)03191-2  0.36
2001 Barnes W, Boyd D, Hough L. Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site? European Journal of Pharmacology. 431: 215-21. PMID 11728428 DOI: 10.1016/S0014-2999(01)01453-4  0.36
2001 Hough LB, Nalwalk JW, Leurs R, Menge WM, Timmerman H. Significance of GABAergic systems in the action of improgan, a non-opioid analgesic. Life Sciences. 68: 2751-7. PMID 11400917 DOI: 10.1016/S0024-3205(01)01080-3  0.36
2001 Hough LB. Genomics meets histamine receptors: new subtypes, new receptors. Molecular Pharmacology. 59: 415-9. PMID 11179433  0.36
2000 Hough LB, Nalwalk JW, Chen Y, Schuller A, Zhu Y, Zhang J, Menge WM, Leurs R, Timmerman H, Pintar JE. Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice. Brain Research. 880: 102-8. PMID 11032994 DOI: 10.1016/S0006-8993(00)02776-1  0.36
2000 Hough LB, Nalwalk JW, Barnes WG, Leurs R, Menge WM, Timmerman H, Wentland M. A third life for burimamide. Discovery and characterization of a novel class of non-opioid analgesics derived from histamine antagonists. Annals of the New York Academy of Sciences. 909: 25-40. PMID 10911922  0.36
2000 Hough LB, Bagal AA, Glick SD. Pharmacokinetic characterization of the indole alkaloid ibogaine in rats. Methods and Findings in Experimental and Clinical Pharmacology. 22: 77-81. PMID 10849889  0.36
2000 McRee RC, Terry-Ferguson M, Langlais PJ, Chen Y, Nalwalk JW, Blumenstock FA, Hough LB. Increased histamine release and granulocytes within the thalamus of a rat model of Wernicke's encephalopathy. Brain Research. 858: 227-36. PMID 10708674 DOI: 10.1016/S0006-8993(99)02309-4  0.36
2000 Hough LB, Nalwalk JW, Leurs R, Menge WM, Timmerman H. Antinociceptive activity of derivatives of improgran and burimamide. Pharmacology, Biochemistry, and Behavior. 65: 61-6. PMID 10638637 DOI: 10.1016/S0091-3057(99)00187-2  0.36
1999 Yates SL, Tedford CE, Gregory R, Pawlowski GP, Handley MK, Boyd DL, Hough LB. Effects of selected histamine H3 receptor antagonists on tele-methylhistamine levels in rat cerebral cortex. Biochemical Pharmacology. 57: 1059-66. PMID 10796076 DOI: 10.1016/S0006-2952(98)00378-5  0.36
1999 Hough LB, Nalwalk JW, Leurs R, Menge WM, Timmerman H. Antinociceptive activity of impentamine, a histamine congener, after CNS administration. Life Sciences. 64: PL79-86. PMID 10072195  0.36
1999 Glick SD, Maisonneuve IM, Hough LB, Kuehne ME, Bandarage UK. (±)- 18-methoxycoronaridine: A novel Iboga alkaloid congener having potential anti-addictive efficacy Cns Drug Reviews. 5: 27-42.  0.36
1998 Bannoura MD, Nalwalk JW, Tang Y, Carlile M, Leurs R, Menge WM, Timmerman H, Hough LB. Absence of antinociceptive tolerance to improgan, a cimetidine analog, in rats. Brain Research. 814: 218-21. PMID 9838126 DOI: 10.1016/S0006-8993(98)01024-5  0.36
1997 Hough LB, Nalwalk JW, Li BY, Leurs R, Menge WM, Timmerman H, Carlile ME, Cioffi C, Wentland M. Novel qualitative structure-activity relationships for the antinociceptive actions of H2 antagonists, H3 antagonists and derivatives. The Journal of Pharmacology and Experimental Therapeutics. 283: 1534-43. PMID 9400031  0.36
1997 Pearl SM, Hough LB, Boyd DL, Glick SD. Sex differences in ibogaine antagonism of morphine-induced locomotor activity and in ibogaine brain levels and metabolism. Pharmacology, Biochemistry, and Behavior. 57: 809-15. PMID 9259010 DOI: 10.1016/S0091-3057(96)00383-8  0.36
1997 Li BY, Nalwalk JW, Hough LB. Effects of naltrexone and histamine antagonists on the antinociceptive activity of the cimetidine analog SKF92374 in rats. Brain Research. 748: 168-74. PMID 9067458 DOI: 10.1016/S0006-8993(96)01288-7  0.36
1996 Bagal AA, Hough LB, Nalwalk JW, Glick SD. Modulation of morphine-induced antinociception by ibogaine and noribogaine. Brain Research. 741: 258-62. PMID 9001731 DOI: 10.1016/S0006-8993(96)00938-9  0.36
1996 Prell GD, Hough LB, Khandelwal J, Green JP. Lack of a precursor-product relationship between histamine and its metabolites in brain after histidine loading. Journal of Neurochemistry. 67: 1938-44. PMID 8863498  0.36
1996 Mischler SA, Hough LB, Battles AH. Characteristics of carbon dioxide-induced antinociception. Pharmacology, Biochemistry, and Behavior. 53: 205-12. PMID 8848452 DOI: 10.1016/0091-3057(95)00181-6  0.36
1996 Hough LB, Pearl SM, Glick SD. Tissue distribution of ibogaine after intraperitoneal and subcutaneous administration. Life Sciences. 58: PL119-22. PMID 8632705 DOI: 10.1016/0024-3205(95)02322-4  0.36
1996 Li BY, Nalwalk JW, Barker LA, Cumming P, Parsons ME, Hough LB. Characterization of the antinociceptive properties of cimetidine and a structural analog. The Journal of Pharmacology and Experimental Therapeutics. 276: 500-8. PMID 8632315  0.36
1995 Hough LB, Nalwalk JW. Role of stress in histamine-morphine interactions. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 44: S40-1. PMID 8520992 DOI: 10.1007/BF01674386  0.36
1995 Gallagher CA, Hough LB, Keefner SM, Seyed-Mozaffari A, Archer S, Glick SD. Identification and quantification of the indole alkaloid ibogaine in biological samples by gas chromatography-mass spectrometry. Biochemical Pharmacology. 49: 73-9. PMID 7840786 DOI: 10.1016/0006-2952(94)00441-N  0.36
1995 Nalwalk JW, Hough LB. Importance of histamine H2 receptors in restraint-morphine interactions. Life Sciences. 57: PL153-8. PMID 7674814 DOI: 10.1016/0024-3205(95)02078-W  0.36
1995 Nalwalk JW, Koch JE, Barke KE, Bodnar RJ, Hough LB. Modulation of morphine antinociception by the brain-penetrating H2 antagonist zolantidine: detailed characterization in five nociceptive test systems. Pharmacology, Biochemistry, and Behavior. 50: 421-9. PMID 7617681 DOI: 10.1016/0091-3057(94)00291-P  0.36
1995 Tedford CE, Yates SL, Pawlowski GP, Nalwalk JW, Hough LB, Khan MA, Phillips JG, Durant GJ, Frederickson RC. Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies. The Journal of Pharmacology and Experimental Therapeutics. 275: 598-604. PMID 7473144  0.36
1994 Skratt JJ, Hough LB, Nalwalk JW, Barke KE. alpha-Fluoromethylhistidine-induced inhibition of brain histidine decarboxylase. Implications for the CO2-trapping enzymatic method. Biochemical Pharmacology. 47: 397-402. PMID 8304983 DOI: 10.1016/0006-2952(94)90031-0  0.36
1994 Servos P, Barke KE, Hough LB, Vanderwolf CH. Histamine does not play an essential role in electrocortical activation during waking behavior. Brain Research. 636: 98-102. PMID 8156416 DOI: 10.1016/0006-8993(94)90180-5  0.36
1994 Mischler SA, Alexander M, Battles AH, Raucci JA, Nalwalk JW, Hough LB. Prolonged antinociception following carbon dioxide anesthesia in the laboratory rat. Brain Research. 640: 322-7. PMID 8004460 DOI: 10.1016/0006-8993(94)91888-0  0.36
1994 Thoburn KK, Hough LB, Nalwalk JW, Mischler SA. Histamine-induced modulation of nociceptive responses. Pain. 58: 29-37. PMID 7970837 DOI: 10.1016/0304-3959(94)90182-1  0.36
1994 Langlais PJ, Zhang SX, Weilersbacher G, Hough LB, Barke KE. Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy. Journal of Neuroscience Research. 38: 565-74. PMID 7529327 DOI: 10.1002/jnr.490380509  0.36
1994 Barke KE, Hough LB. Characterization of basal and morphine-induced histamine release in the rat periaqueductal gray. Journal of Neurochemistry. 63: 238-44. PMID 7515945  0.36
1993 Barke KE, Hough LB. Opiates, mast cells and histamine release. Life Sciences. 53: 1391-9. PMID 7694026 DOI: 10.1016/0024-3205(93)90581-M  0.36
1993 Barke KE, Hough LB. Simultaneous measurement of opiate-induced histamine release in the periaqueductal gray and opiate antinociception: an in vivo microdialysis study. The Journal of Pharmacology and Experimental Therapeutics. 266: 934-42. PMID 7689107  0.36
1992 Barke KE, Hough LB. Morphine-induced increases of extracellular histamine levels in the periaqueductal grey in vivo: a microdialysis study. Brain Research. 572: 146-53. PMID 1611509 DOI: 10.1016/0006-8993(92)90463-J  0.36
1992 Glick SD, Gallagher CA, Hough LB, Rossman KL, Maisonneuve IM. Differential effects of ibogaine pretreatment on brain levels of morphine and (+)-amphetamine. Brain Research. 588: 173-6. PMID 1393568 DOI: 10.1016/0006-8993(92)91360-Q  0.36
1992 Swaab RL, Battles AM, Bruner CA, Hough LB. Dimaprit--induced neurotoxicity. Agents and Actions. 35: 179-84. PMID 1388319 DOI: 10.1007/BF01997497  0.36
1992 Hough LB, Nalwalk JW. Modulation of morphine antinociception by antagonism of H2 receptors in the periaqueductal gray. Brain Research. 588: 58-66. PMID 1356588 DOI: 10.1016/0006-8993(92)91344-E  0.36
1992 Hough LB, Nalwalk JW. Inhibition of morphine antinociception by centrally administered histamine H2 receptor antagonists. European Journal of Pharmacology. 215: 69-74. PMID 1355443 DOI: 10.1016/0014-2999(92)90610-G  0.36
1992 Koch JE, Hough LB, Bodnar RJ. Potentiation of 2-deoxy-D-glucose antinociception, but not hyperphagia by zolantidine, a histamine (H2) receptor antagonist. Pharmacology, Biochemistry, and Behavior. 41: 371-6. PMID 1349437 DOI: 10.1016/0091-3057(92)90113-T  0.36
1991 Kishikawa H, Willinger SM, Jackowski S, Barke K, Hough LB. Histidine decarboxylase measurement in brain by 14CO2 trapping. Biochemical Pharmacology. 42: 217-22. PMID 1907141 DOI: 10.1016/0006-2952(91)90706-B  0.36
1990 Licata SP, Nalwalk JW, Hough LB. Actions of morphine on histamine dynamics in the mouse brain: a strain comparison. Biochemical Pharmacology. 39: 978-81. PMID 2310423 DOI: 10.1016/0006-2952(90)90219-B  0.36
1990 Licata SP, Nalwalk JW, Hough LB. Differential effects of morphine on histamine metabolism in brain and spinal cord of mice. Brain Research. 521: 125-30. PMID 2207651 DOI: 10.1016/0006-8993(90)91532-L  0.36
1989 Prell GD, Khandelwal JK, Hough LB, Green JP. pros-methylimidazoleacetic acid in rat brain: its regional distribution and relationship to metabolic pathways of histamine. Journal of Neurochemistry. 52: 561-7. PMID 2911030  0.36
1989 Thompson C, Blumenstock FA, Saba TM, Feustel PJ, Kaplan JE, Fortune JB, Hough L, Gray V. Plasma fibronectin synthesis in normal and injured humans as determined by stable isotope incorporation Journal of Clinical Investigation. 84: 1226-1235. PMID 2794059  0.36
1989 Gogas KR, Hough LB. Inhibition of naloxone-resistant antinociception by centrally administered H2-antagonists. The Journal of Pharmacology and Experimental Therapeutics. 248: 262-7. PMID 2563290  0.36
1989 Gogas KR, Hough LB, Eberle NB, Lyon RA, Glick SD, Ward SJ, Young RC, Parsons ME. A role for histamine and H2-receptors in opioid antinociception. The Journal of Pharmacology and Experimental Therapeutics. 250: 476-84. PMID 2547933  0.36
1989 Gannon MN, Hough LB, Weinstein H. A metactoid sensitization model to describe multiple receptors linked to a common response: application to histamine receptors coupled to [3H]cyclic AMP accumulation in guinea pig cortex. Molecular Pharmacology. 35: 205-13. PMID 2537458  0.36
1988 Licata SP, Werber AH, Hough LB. Cimetidine-sensitive analgesia: investigation of the importance of stress-induced changes in arterial pressure. Physiology & Behavior. 42: 563-8. PMID 3413231 DOI: 10.1016/0031-9384(88)90158-8  0.36
1988 Weinstein IJ, Hough LB, Gogas KR. Cross-tolerance and cross-sensitization between morphine analgesia and naloxone-sensitive and cimetidine-sensitive stress-induced analgesia. The Journal of Pharmacology and Experimental Therapeutics. 244: 253-8. PMID 3336002  0.36
1988 Hough LB. Cellular localization and possible functions for brain histamine: recent progress. Progress in Neurobiology. 30: 469-505. PMID 3287452 DOI: 10.1016/0301-0082(88)90032-9  0.36
1988 Hough LB, Jackowski S, Eberle N, Gogas KR, Camarota NA, Cue D. Actions of the brain-penetrating H2-antagonist zolantidine on histamine dynamics and metabolism in rat brain. Biochemical Pharmacology. 37: 4707-11. PMID 3202904 DOI: 10.1016/0006-2952(88)90341-3  0.36
1988 Gogas KR, Hough LB. H2-receptor-mediated stress-induced analgesia is dependent on neither pituitary nor adrenal activation. Pharmacology, Biochemistry, and Behavior. 30: 791-4. PMID 2905473 DOI: 10.1016/0091-3057(88)90101-3  0.36
1988 Gogas KR, Hough LB. Effects of zolantidine a brain-penetrating H2-receptor antagonist, on naloxone-sensitive and naloxone-resistant analgesia. Neuropharmacology. 27: 357-62. PMID 2901671 DOI: 10.1016/0028-3908(88)90143-8  0.36
1988 Robertson JA, Hough LB, Bodnar RJ. Potentiation of opioid and nonopioid forms of swim analgesia by cimetidine. Pharmacology, Biochemistry, and Behavior. 31: 107-12. PMID 2855266 DOI: 10.1016/0091-3057(88)90320-6  0.36
1988 Gannon MN, Hough LB. Histamine receptors coupled to [3H]cAMP accumulation in brain: pharmacological characterization in a vesicular preparation of guinea pig cortex. Molecular Pharmacology. 33: 44-50. PMID 2826998  0.36
1987 Newton MV, Hough LB, Weinstein H. A metactoid-sensitization model for the classification of histamine receptors coupled to [3H]cAMP accumulation in a vesicular preparation of guinea pig cerebral cortex Annals of the New York Academy of Sciences. 494: 243-246.  0.36
1986 Hough LB, Khandelwal JK, Green JP. Inhibition of brain histamine metabolism by metoprine. Biochemical Pharmacology. 35: 307-10. PMID 3942601 DOI: 10.1016/0006-2952(86)90530-7  0.36
1986 Gogas KR, Hough LB, Glick SD, Su K. Opposing actions of cimetidine on naloxone-sensitive and naloxone-insensitive forms of footshock-induced analgesia. Brain Research. 370: 370-4. PMID 3708333 DOI: 10.1016/0006-8993(86)90496-8  0.36
1986 Hough LB, Glick SD, Su K. Cimetidine penetrates brain and inhibits non-opiate footshock-induced analgesia. Pharmacology, Biochemistry, and Behavior. 24: 1257-61. PMID 3487801 DOI: 10.1016/0091-3057(86)90181-4  0.36
1986 Shapiro RM, Glick SD, Hough LB. Striatal dopamine uptake asymmetries and rotational behavior in unlesioned rats: revising the model? Psychopharmacology. 89: 25-30. PMID 3090589 DOI: 10.1007/BF00175184  0.36
1986 Gannon MN, Hough LB. Properties of a 3H-adenine prelabeled vesicular preparation from guinea pig cerebral cortex. Optimization of incubation conditions for basal- and histamine-stimulated 3H-cyclic AMP levels. Journal of Pharmacological Methods. 16: 315-28. PMID 3023756 DOI: 10.1016/0160-5402(86)90034-3  0.36
1985 Goldschmidt RC, Hough LB, Glick SD. Rat brain mast cells: contribution to brain histamine levels. Journal of Neurochemistry. 44: 1943-7. PMID 3989570 DOI: 10.1111/j.1471-4159.1985.tb07191.x  0.36
1985 Hough LB, Glick SD, Su K. A role for histamine and histamine H2-receptors in non-opiate footshock-induced analgesia. Life Sciences. 36: 859-66. PMID 2858046 DOI: 10.1016/0024-3205(85)90210-3  0.36
1984 Hough LB, Khandelwal JK, Goldschmidt RC, Diomande M, Glick SD. Normal levels of histamine and tele-methylhistamine in mast cell-deficient mouse brain. Brain Research. 292: 133-8. PMID 6697200 DOI: 10.1016/0006-8993(84)90897-7  0.36
1984 Hough LB, Khandelwal JK, Green JP. Histamine turnover in regions of rat brain. Brain Research. 291: 103-9. PMID 6697175 DOI: 10.1016/0006-8993(84)90655-3  0.36
1984 Khandelwal JK, Hough LB, Green JP. Regional distribution of the histamine metabolite, tele-methylimidazoleacetic acid, in rat brain: effects of pargyline and probenecid. Journal of Neurochemistry. 42: 519-22. PMID 6693885  0.36
1984 Hough LB, Su KL, Goldschmidt RC, Khandelwal JK, Newton MV, Glick SD. No evidence for histamine-mediated morphine analgesia. Neuropharmacology. 23: 705-9. PMID 6462376 DOI: 10.1016/0028-3908(84)90169-2  0.36
1984 Goldschmidt RC, Khandelwal JK, Hough LB. Presence and measurement of tele-methylhistamine in mast cells. Agents and Actions. 14: 174-8. PMID 6201055 DOI: 10.1007/BF01966638  0.36
1984 Goldschmidt RC, Hough LB, Glick SD, Padawer J. Mast cells in rat thalamus: nuclear localization, sex difference and left-right asymmetry. Brain Research. 323: 209-17. PMID 6084538 DOI: 10.1016/0006-8993(84)90291-9  0.36
1984 Khandelwal JK, Hough LB, Kline T, Green JP. SIMULTANEOUS MEASUREMENT OF HISTAMINE METABOLITES BY GC-MS Annual Conference On Mass Spectrometry and Allied Topics. 73.  0.36
1984 Goldschmidt RC, Hough LB, Glick SD, Padawer J. Characterization of mast cells in rat brain Federation Proceedings. 43: no. 3935.  0.36
1983 Barker LA, Hough LB. Selectivity of 4-methylhistamine at H1- and H2-receptors in the guinea-pig isolated ileum. British Journal of Pharmacology. 80: 65-71. PMID 6228278  0.36
1982 Khandelwal JK, Hough LB, Morrishow AM, Green JP. Measurement of tele-methylhistamine and histamine in human cerebrospinal fluid, urine, and plasma. Agents and Actions. 12: 583-90. PMID 7164933 DOI: 10.1007/BF01965064  0.36
1982 Hough LB, Khandelwal JK, Green JP. Effects of pargyline on tele-methylhistamine and histamine in rat brain. Biochemical Pharmacology. 31: 4074-6. PMID 7159483 DOI: 10.1016/0006-2952(82)90660-8  0.36
1982 Khandelwal JK, Hough LB, Green JP. Histamine and some of its metabolites in human body fluids. Klinische Wochenschrift. 60: 914-8. PMID 7132243  0.36
1982 Khandelwal JK, Hough LB, Pazhenchevsky B, Morrishow AM, Green JP. Presence and measurement of methylimidazoleacetic acids in brain and body fluids. The Journal of Biological Chemistry. 257: 12815-9. PMID 7130180  0.36
1982 Hough LB, Khandelwal JK, Green JP. Ontogeny of subcellular distribution of rat brain tele-methylhistamine. Journal of Neurochemistry. 38: 1593-9. PMID 7077329  0.36
1982 Newton MV, Hough LB, Azmitia EC. Histamine-sensitive adenylate cyclase in monkey brain. Brain Research. 239: 639-43. PMID 6284312 DOI: 10.1016/0006-8993(82)90542-X  0.36
1982 Maayani S, Hough LB, Weinstein H, Green JP. Response of the histamine h2-receptor in brain to antidepressant drugs. Advances in Biochemical Psychopharmacology. 31: 133-47. PMID 6123221  0.36
1982 Glick SD, Ross DA, Hough LB. Lateral asymmetry of neurotransmitters in human brain. Brain Research. 234: 53-63. PMID 6120746 DOI: 10.1016/0006-8993(82)90472-3  0.36
1982 Goldschmidt RC, Khandelwal JK, Hough LB. Presence and characterization of tele-methylhistamine in mast cells Federation Proceedings. 41: No. 8416.  0.36
1981 Hough LB, Khandelwal JK, Mittag TW. Alpha-methylhistamine methylation by histamine methyltransferase. Agents and Actions. 11: 425-8. PMID 7337069 DOI: 10.1007/BF02004701  0.36
1981 Hough LB, Khandelwal JK, Morrishow AM, Green JP. An improved GCMS method to measure tele-methylhistamine. Journal of Pharmacological Methods. 5: 143-8. PMID 7230838 DOI: 10.1016/0160-5402(81)90006-1  0.36
1981 Hough LB, Green JP. Histamine-activated adenylate cyclase in brain homogenates of several species. Brain Research. 219: 363-70. PMID 6266607 DOI: 10.1016/0006-8993(81)90299-7  0.36
1981 Hough LB, Barker LA. Histamine H2-receptor antagonism by propantheline and derivatives. The Journal of Pharmacology and Experimental Therapeutics. 219: 453-8. PMID 6116801  0.36
1981 Hough LB. Tricyclic anticholinergic drugs block brain H2-receptors Federation Proceedings. 40: 2519.  0.36
1981 Hough LB, Khandelwal JK, Green JP. Sex-related differenced in rat brain tele-methylhistamine Federation Proceedings. 40: 2520.  0.36
1980 Hough LB, Green JP. Possible functions of brain histamine. Psychopharmacology Bulletin. 16: 42-4. PMID 7360838  0.36
1980 Green JP, Maayani S, Weinstein H, Hough LB. Histamine and psychotropic drugs. Psychopharmacology Bulletin. 16: 36-8. PMID 7360834  0.36
1980 Hough LB, Weinstein H, Green JP. One agonist and two receptors mediating the same effect: histamine receptors linked to adenylate cyclase in the brain. Advances in Biochemical Psychopharmacology. 21: 183-92. PMID 6103645  0.36
1979 Hough LB, Stetson PL, Domino EF. Gas chromatography--mass spectrometric characteristics and assay of tele-methylhistamine. Analytical Biochemistry. 96: 56-63. PMID 495991 DOI: 10.1016/0003-2697(79)90553-0  0.36
1979 Hough LB, Domino EF. Tele-methylhistamine distribution in rat brain. Journal of Neurochemistry. 32: 1865-6. PMID 448374  0.36
1979 Hough LB, Domino EF. Tele-methylhistamine oxidation by type B monoamine oxidase. The Journal of Pharmacology and Experimental Therapeutics. 208: 422-8. PMID 430361  0.36
1978 Tessel RE, Smith CB, Russ DN, Hough LB. The effects of cocaine HC1 and a quaternary derivative of cocaine, cocaine methiodide, on isolated guinea-pig and rat atria. The Journal of Pharmacology and Experimental Therapeutics. 205: 568-76. PMID 660530  0.36
1978 Hough LB, Domino EF. Tele-Methylhistamine oxidation by type B MAO Pharmacologist. 20: 633.  0.36
1978 Tessel RE, Smith CB, Russ DN, Hough LB. The effects of cocaine HCl and a quaternary derivative of cocaine, cocaine methiodide, on isolated guinea pig and rat atria Journal of Pharmacology and Experimental Therapeutics. 205: 569-576.  0.36
1977 Hough LB, Domino EF. Elevation in rat brain histamine content after focused microwave irradiation. Journal of Neurochemistry. 29: 199-204. PMID 886326  0.36
1977 Salberg DJ, Hough LB, Kaplan DE, Domino EF. A reverse double-isotope enzymatic histamine assay: advantages over single-isotope methods. Life Sciences. 21: 1439-46. PMID 73117 DOI: 10.1016/0024-3205(77)90198-9  0.36
1977 Hough LB, Domino EF. Gas chromatography mass fragmentography assay of rat brain 3-methylhistamine Federation Proceedings. 36: No.3691.  0.36
1975 Hough LB, Domino EF. The effect of focusing microwave irradiation (MWI), on rat brain histamine (H) Pharmacologist. 17: 028.  0.36
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