Raymond A. Sobel, MD - Publications

Affiliations: 
Pathology Stanford University, Palo Alto, CA 
Area:
Cellular and molecular mechanisms of immune responses in the central nervous system; multiple sclerosis.
Website:
http://med.stanford.edu/profiles/neuroscience/faculty/Raymond_Sobel

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Wang C, Yosef N, Gaublomme J, Wu C, Lee Y, Clish CB, Kaminski J, Xiao S, Zu Horste GM, Pawlak M, Kishi Y, Joller N, Karwacz K, Zhu C, Ordovas-Montanes M, ... ... Sobel RA, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. PMID 26607793 DOI: 10.1016/j.cell.2015.10.068  0.32
2014 Graham KL, Zhang JV, Lewén S, Burke TM, Dang T, Zoudilova M, Sobel RA, Butcher EC, Zabel BA. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. Plos One. 9: e112925. PMID 25437209 DOI: 10.1371/journal.pone.0112925  0.32
2014 Massilamany C, Marciano-Cabral F, Rocha-Azevedo Bd, Jamerson M, Gangaplara A, Steffen D, Zabad R, Illes Z, Sobel RA, Reddy J. SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens. Plos One. 9: e98506. PMID 24879066 DOI: 10.1371/journal.pone.0098506  0.32
2014 Wang D, Bhat R, Sobel RA, Huang W, Wang LX, Olsson T, Steinman L. Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug Development Research. 75: 172-88. PMID 24648292 DOI: 10.1002/ddr.21169  0.32
2013 Molnarfi N, Schulze-Topphoff U, Weber MS, Patarroyo JC, Prod'homme T, Varrin-Doyer M, Shetty A, Linington C, Slavin AJ, Hidalgo J, Jenne DE, Wekerle H, Sobel RA, Bernard CC, Shlomchik MJ, et al. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. The Journal of Experimental Medicine. 210: 2921-37. PMID 24323356 DOI: 10.1084/jem.20130699  0.32
2013 Hsu JL, Khan MA, Sobel RA, Jiang X, Clemons KV, Nguyen TT, Stevens DA, Martinez M, Nicolls MR. Aspergillus fumigatus invasion increases with progressive airway ischemia. Plos One. 8: e77136. PMID 24155924 DOI: 10.1371/journal.pone.0077136  0.32
2013 Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, et al. Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nature Immunology. 14: 1166-72. PMID 24076635 DOI: 10.1038/ni.2730  0.32
2013 Kurnellas MP, Adams CM, Sobel RA, Steinman L, Rothbard JB. Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation. Science Translational Medicine. 5: 179ra42. PMID 23552370 DOI: 10.1126/scitranslmed.3005681  0.32
2012 Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9. PMID 22961052 DOI: 10.1038/ni.2416  0.32
2012 Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB. Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. The Journal of Biological Chemistry. 287: 36423-34. PMID 22955287 DOI: 10.1074/jbc.M112.371229  0.32
2012 Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, et al. Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. Nature Medicine. 18: 1394-400. PMID 22863785 DOI: 10.1038/nm.2871  0.32
2012 Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 12105-10. PMID 22773818 DOI: 10.1073/pnas.1120914109  0.32
2012 Schulze-Topphoff U, Shetty A, Varrin-Doyer M, Molnarfi N, Sagan SA, Sobel RA, Nelson PA, Zamvil SS. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. Plos One. 7: e33797. PMID 22479444 DOI: 10.1371/journal.pone.0033797  0.32
2012 Anderson AC, Chandwaskar R, Lee DH, Sullivan JM, Solomon A, Rodriguez-Manzanet R, Greve B, Sobel RA, Kuchroo VK. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2084-92. PMID 22279107 DOI: 10.4049/jimmunol.1102186  0.32
2012 Sternberg Z, Cesario A, Rittenhouse-Olson K, Sobel RA, Leung YK, Pankewycz O, Zhu B, Whitcomb T, Sternberg DS, Munschauer FE. Acamprosate modulates experimental autoimmune encephalomyelitis. Inflammopharmacology. 20: 39-48. PMID 22090150 DOI: 10.1007/s10787-011-0097-1  0.32
2012 Zerboni L, Sobel RA, Lai M, Triglia R, Steain M, Abendroth A, Arvin A. Apparent expression of varicella-zoster virus proteins in latency resulting from reactivity of murine and rabbit antibodies with human blood group a determinants in sensory neurons. Journal of Virology. 86: 578-83. PMID 22013055 DOI: 10.1128/JVI.05950-11  0.32
2011 Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity. 35: 986-96. PMID 22177922 DOI: 10.1016/j.immuni.2011.10.015  0.32
2011 Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. Journal of Clinical Immunology. 31: 1010-20. PMID 21847523 DOI: 10.1007/s10875-011-9579-6  0.32
2011 Qi X, Disatnik MH, Shen N, Sobel RA, Mochly-Rosen D. Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo. Molecular Biology of the Cell. 22: 256-65. PMID 21119009 DOI: 10.1091/mbc.E10-06-0551  0.32
2010 Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A, Nguyen K, Mukundan L, Moshkova M, Dugas JC, Chawla A, Steinman L. Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. The Journal of Experimental Medicine. 207: 1599-608. PMID 20624891 DOI: 10.1084/jem.20091663  0.32
2010 Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, Cornejo M, Nishi N, Yamauchi A, Quintana FJ, Sobel RA, Hirashima M, Kuchroo VK. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 1383-92. PMID 20574007 DOI: 10.4049/jimmunol.0903275  0.32
2010 Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radical Biology & Medicine. 48: 1501-12. PMID 20188820 DOI: 10.1016/j.freeradbiomed.2010.02.028  0.32
2010 Zerboni L, Sobel RA, Ramachandran V, Rajamani J, Ruyechan W, Abendroth A, Arvin A. Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia. Journal of Virology. 84: 3421-30. PMID 20106930 DOI: 10.1128/JVI.02416-09  0.32
2009 Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. Journal of Immunology (Baltimore, Md. : 1950). 183: 7169-77. PMID 19890056 DOI: 10.4049/jimmunol.0901906  0.32
2009 Graham KL, Zabel BA, Loghavi S, Zuniga LA, Ho PP, Sobel RA, Butcher EC. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 6717-23. PMID 19864606 DOI: 10.4049/jimmunol.0803435  0.32
2009 Araki M, Chung D, Liu S, Rainbow DB, Chamberlain G, Garner V, Hunter KM, Vijayakrishnan L, Peterson LB, Oukka M, Sharpe AH, Sobel R, Kuchroo VK, Wicker LS. Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5146-57. PMID 19783679 DOI: 10.4049/jimmunol.0802610  0.32
2009 Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14948-53. PMID 19706421 DOI: 10.1073/pnas.0903958106  0.32
2009 Ganjoo KN, Raman R, Sobel RA, Pinto HA. Opportunistic enteroviral meningoencephalitis: an unusual treatable complication of rituximab therapy. Leukemia & Lymphoma. 50: 673-5. PMID 19373672 DOI: 10.1080/10428190902782210  0.32
2009 Clemons KV, Capilla J, Sobel RA, Martinez M, Tong AJ, Stevens DA. Comparative efficacies of lipid-complexed amphotericin B and liposomal amphotericin B against coccidioidal meningitis in rabbits. Antimicrobial Agents and Chemotherapy. 53: 1858-62. PMID 19273680 DOI: 10.1128/AAC.01538-08  0.32
2008 Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nature Immunology. 9: 1347-55. PMID 18997793 DOI: 10.1038/ni.1677  0.32
2008 Sobel RA. A novel unifying hypothesis of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 67: 1032-4. PMID 18978540 DOI: 10.1097/NEN.0b13e31818becal  0.32
2008 Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 expressed on APCs induces T cell expansion and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 4706-13. PMID 18354194  0.32
2008 Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 451: 1076-81. PMID 18278032 DOI: 10.1038/nature06559  0.32
2008 Liao YJ, Safa P, Chen YR, Sobel RA, Boyden ES, Tsien RW. Anti-Ca2+ channel antibody attenuates Ca2+ currents and mimics cerebellar ataxia in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 2705-10. PMID 18272482 DOI: 10.1073/pnas.0710771105  0.32
2008 Qi X, Inagaki K, Sobel RA, Mochly-Rosen D. Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats. The Journal of Clinical Investigation. 118: 173-82. PMID 18097471 DOI: 10.1172/JCI32636  0.32
2007 Qin Y, Sobel RA. Mechanisms of injury in multiple sclerosis: involvement of antineuroaxonal humoral autoimmunity. Expert Review of Clinical Immunology. 3: 653-7. PMID 20477013 DOI: 10.1586/1744666X.3.5.653  0.32
2007 Sobel RA. Neuropathology--for the living and the future. Journal of Neuropathology and Experimental Neurology. 66: 1057-8. PMID 18090914 DOI: 10.1097/NEN.0b013e31815d8c10  0.32
2007 Illés Z, Waldner H, Reddy J, Anderson AC, Sobel RA, Kuchroo VK. Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background. International Immunology. 19: 1235-48. PMID 17804690 DOI: 10.1093/intimm/dxm094  0.32
2007 Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, Patarroyo JC, Stüve O, Sobel RA, Steinman L, Zamvil SS. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nature Medicine. 13: 935-43. PMID 17676050 DOI: 10.1038/nm1620  0.32
2007 Capilla J, Clemons KV, Sobel RA, Stevens DA. Efficacy of amphotericin B lipid complex in a rabbit model of coccidioidal meningitis. The Journal of Antimicrobial Chemotherapy. 60: 673-6. PMID 17646202 DOI: 10.1093/jac/dkm264  0.32
2007 Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. The Journal of Experimental Medicine. 204: 1691-702. PMID 17606630 DOI: 10.1084/jem.20062498  0.32
2007 Greve B, Weissert R, Hamdi N, Bettelli E, Sobel RA, Coyle A, Kuchroo VK, Rajewsky K, Schmidt-Supprian M. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 179-85. PMID 17579036  0.32
2007 Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'Connor KC, Hafler DA, Sobel RA, Robinson WH, Steinman L. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature. 448: 474-9. PMID 17568699 DOI: 10.1038/nature05935  0.32
2007 Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nature Medicine. 13: 423-31. PMID 17384649 DOI: 10.1038/nm1564  0.32
2007 Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. The Journal of Experimental Medicine. 204: 321-30. PMID 17261635 DOI: 10.1084/jem.20061839  0.32
2007 Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. The Journal of Clinical Investigation. 117: 438-47. PMID 17256058 DOI: 10.1172/JCI28844  0.32
2007 Sobel RA. Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse? The American Journal of Pathology. 170: 436-8. PMID 17255311 DOI: 10.2353/ajpath.2007.061098  0.32
2007 Kamberi P, Sobel RA, Clemons KV, Waldvogel A, Striebel JM, Williams PL, Stevens DA. Comparison of itraconazole and fluconazole treatments in a murine model of coccidioidal meningitis. Antimicrobial Agents and Chemotherapy. 51: 998-1003. PMID 17178793 DOI: 10.1128/AAC.00332-06  0.32
2007 Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nature Immunology. 8: 74-83. PMID 17143274 DOI: 10.1038/ni1415  0.32
2006 Capilla J, Maffei CM, Clemons KV, Sobel RA, Stevens DA. Experimental systemic infection with Cryptococcus neoformans var. grubii and Cryptococcus gattii in normal and immunodeficient mice. Medical Mycology. 44: 601-10. PMID 17071553 DOI: 10.1080/13693780600810040  0.32
2006 Bettelli E, Baeten D, Jäger A, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of Clinical Investigation. 116: 2393-402. PMID 16955141 DOI: 10.1172/JCI28334  0.32
2006 Waldner H, Sobel RA, Price N, Kuchroo VK. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 5455-62. PMID 16622013  0.32
2006 Stüve O, Youssef S, Weber MS, Nessler S, von Büdingen HC, Hemmer B, Prod'homme T, Sobel RA, Steinman L, Zamvil SS. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. The Journal of Clinical Investigation. 116: 1037-44. PMID 16543951 DOI: 10.1172/JCI25805  0.32
2006 Zucker KE, Kamberi P, Sobel RA, Cloud G, Meli DN, Clemons KV, Stevens DA, Williams PL, Leib SL. Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis. Clinical and Experimental Immunology. 143: 458-66. PMID 16487245 DOI: 10.1111/j.1365-2249.2006.03011.x  0.32
2006 Greenfield EA, Reddy J, Lees A, Dyer CA, Koul O, Nguyen K, Bell S, Kassam N, Hinojoza J, Eaton MJ, Lees MB, Kuchroo VK, Sobel RA. Monoclonal antibodies to distinct regions of human myelin proteolipid protein simultaneously recognize central nervous system myelin and neurons of many vertebrate species. Journal of Neuroscience Research. 83: 415-31. PMID 16416423 DOI: 10.1002/jnr.20748  0.32
2006 Kanter JL, Narayana S, Ho PP, Catz I, Warren KG, Sobel RA, Steinman L, Robinson WH. Lipid microarrays identify key mediators of autoimmune brain inflammation. Nature Medicine. 12: 138-43. PMID 16341241 DOI: 10.1038/nm1344  0.32
2005 Miyamoto K, Kingsley CI, Zhang X, Jabs C, Izikson L, Sobel RA, Weiner HL, Kuchroo VK, Sharpe AH. The ICOS molecule plays a crucial role in the development of mucosal tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 7341-7. PMID 16301640  0.32
2005 Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science (New York, N.Y.). 310: 850-5. PMID 16272121 DOI: 10.1126/science.1117634  0.32
2005 Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, et al. A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 175: 6226-34. PMID 16237121  0.32
2005 Reddy J, Waldner H, Zhang X, Illes Z, Wucherpfennig KW, Sobel RA, Kuchroo VK. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 5591-5. PMID 16237044  0.32
2005 Zhang Y, Da RR, Hilgenberg LG, Tourtellotte WW, Sobel RA, Smith MA, Olek M, Nagra R, Sudhir G, van den Noort S, Qin Y. Clonal expansion of IgA-positive plasma cells and axon-reactive antibodies in MS lesions. Journal of Neuroimmunology. 167: 120-30. PMID 16099056 DOI: 10.1016/j.jneuroim.2005.05.006  0.32
2005 Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Tim-2 regulates T helper type 2 responses and autoimmunity. The Journal of Experimental Medicine. 202: 437-44. PMID 16043519 DOI: 10.1084/jem.20050308  0.32
2005 Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. Journal of Immunology (Baltimore, Md. : 1950). 175: 1558-65. PMID 16034094  0.32
2005 Zhang Y, Da RR, Guo W, Ren HM, Hilgenberg LG, Sobel RA, Tourtellotte WW, Smith MA, Olek M, Gupta S, Robertson RT, Nagra R, Van Den Noort S, Qin Y. Axon reactive B cells clonally expanded in the cerebrospinal fluid of patients with multiple sclerosis. Journal of Clinical Immunology. 25: 254-64. PMID 15981091 DOI: 10.1007/s10875-005-4083-5  0.32
2005 Sobel RA. Ephrin A receptors and ligands in lesions and normal-appearing white matter in multiple sclerosis. Brain Pathology (Zurich, Switzerland). 15: 35-45. PMID 15779235  0.32
2005 Clemons KV, Kamberi P, Chiller TM, Sobel RA, Brummer E, Kolls J, Stevens DA. Effects of interferon-gene therapy in the murine central nervous system and concentrations in cerebrospinal fluid after intrathecal or intracerebral administration Biotechnology. 4: 11-18.  0.32
2004 Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L. Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 6981-92. PMID 15557195  0.32
2004 Reddy J, Illes Z, Zhang X, Encinas J, Pyrdol J, Nicholson L, Sobel RA, Wucherpfennig KW, Kuchroo VK. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15434-9. PMID 15492218 DOI: 10.1073/pnas.0404444101  0.32
2004 Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, Kuchroo VK, Freeman GJ, Sharpe AH. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 10691-6. PMID 15249675 DOI: 10.1073/pnas.0307252101  0.32
2004 Anderson AC, Reddy J, Nazareno R, Sobel RA, Nicholson LB, Kuchroo VK. IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 828-34. PMID 15240669  0.32
2004 Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/jem.20031819  0.32
2004 Greve B, Reddy J, Waldner HP, Sobel RA, Kuchroo VK. Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes. European Journal of Immunology. 34: 1828-38. PMID 15214031 DOI: 10.1002/eji.200425116  0.32
2004 Greve B, Vijayakrishnan L, Kubal A, Sobel RA, Peterson LB, Wicker LS, Kuchroo VK. The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 157-63. PMID 15210770  0.32
2004 Maffei CM, Mirels LF, Sobel RA, Clemons KV, Stevens DA. Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis. Infection and Immunity. 72: 2338-49. PMID 15039359 DOI: 10.1128/IAI.72.4.2338-2349.2004  0.32
2004 Klein RS, Izikson L, Means T, Gibson HD, Lin E, Sobel RA, Weiner HL, Luster AD. IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 172: 550-9. PMID 14688366  0.32
2003 Kaufman DL, Heinrich BS, Willett C, Perry A, Finseth F, Sobel RA, MacCollin M. Somatic instability of the NF2 gene in schwannomatosis. Archives of Neurology. 60: 1317-20. PMID 12975302 DOI: 10.1001/archneur.60.9.1317  0.32
2003 Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. European Journal of Immunology. 33: 2022-2032. PMID 12884869 DOI: 10.1002/eji.200323180  0.32
2003 Yenari MA, Zhao H, Giffard RG, Sobel RA, Sapolsky RM, Steinberg GK. Gene therapy and hypothermia for stroke treatment. Annals of the New York Academy of Sciences. 993: 54-68; discussion 79. PMID 12853295  0.32
2003 Han HS, Karabiyikoglu M, Kelly S, Sobel RA, Yenari MA. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 589-98. PMID 12771574 DOI: 10.1097/01.WCB.0000059566.39780.8D  0.32
2003 Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of Experimental Medicine. 197: 1073-81. PMID 12732654 DOI: 10.1084/jem.20021603  0.32
2003 Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, Madanat R, Garren H, Fontoura P, Tsai M, Galli SJ, Sobel RA, Steinman L. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proceedings of the National Academy of Sciences of the United States of America. 100: 1867-72. PMID 12576552 DOI: 10.1073/pnas.252777399  0.32
2003 Kamberi P, Sobel RA, Clemons KV, Stevens DA, Pappagianis D, Williams PL. A murine model of coccidioidal meningitis. The Journal of Infectious Diseases. 187: 453-60. PMID 12552429 DOI: 10.1086/367961  0.32
2003 Chiller TM, Sobel RA, Luque JC, Clemons KV, Stevens DA. Efficacy of amphotericin B or itraconazole in a murine model of central nervous system Aspergillus infection. Antimicrobial Agents and Chemotherapy. 47: 813-5. PMID 12543700 DOI: 10.1128/AAC.47.2.813-815.2003  0.32
2002 Williams PL, Leib SL, Kamberi P, Leppert D, Sobel RA, Bifrare YD, Clemons KV, Stevens DA. Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis. The Journal of Infectious Diseases. 186: 1692-5. PMID 12447750 DOI: 10.1086/345365  0.32
2002 Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420: 78-84. PMID 12422218 DOI: 10.1038/nature01158  0.32
2002 Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. European Journal of Immunology. 32: 2687-97. PMID 12207354 DOI: 10.1002/1521-4141(200209)32:9<2687::AID-IMMU2687>3.0.CO;2-1  0.32
2002 Chiller TM, Luque JC, Sobel RA, Farrokhshad K, Clemons KV, Stevens DA. Development of a murine model of cerebral aspergillosis. The Journal of Infectious Diseases. 186: 574-7. PMID 12195389 DOI: 10.1086/341567  0.32
2002 Kuruganti PA, Hinojoza JR, Eaton MJ, Ehmann UK, Sobel RA. Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 61: 710-24. PMID 12152786  0.32
2002 Clemons KV, Sobel RA, Williams PL, Pappagianis D, Stevens DA. Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits. Antimicrobial Agents and Chemotherapy. 46: 2420-6. PMID 12121913 DOI: 10.1128/AAC.46.8.2420-2426.2002  0.32
2002 Hurwitz AA, Sullivan TJ, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 3013-7. PMID 11867713 DOI: 10.1073/pnas.042684699  0.32
2002 Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 415: 536-41. PMID 11823861 DOI: 10.1038/415536a  0.32
2001 Sobel RA, Ahmed AS. White matter extracellular matrix chondroitin sulfate/dermatan sulfate proteoglycans in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 60: 1198-207. PMID 11764092  0.32
2001 Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (New York, N.Y.). 294: 1731-5. PMID 11721059 DOI: 10.1126/science.1062960  0.32
2001 Zhang Z, Sobel RA, Cheng D, Steinberg GK, Yenari MA. Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia. Brain Research. Molecular Brain Research. 95: 75-85. PMID 11687278 DOI: 10.1016/S0169-328X(01)00247-9  0.32
2001 Ringer TM, Neumann-Haefelin T, Sobel RA, Moseley ME, Yenari MA. Reversal of early diffusion-weighted magnetic resonance imaging abnormalities does not necessarily reflect tissue salvage in experimental cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 32: 2362-9. PMID 11588327  0.32
2001 Greer JM, Denis B, Sobel RA, Trifilieff E. Thiopalmitoylation of myelin proteolipid protein epitopes enhances immunogenicity and encephalitogenicity. Journal of Immunology (Baltimore, Md. : 1950). 166: 6907-13. PMID 11359852  0.32
2001 Sobel RA. The extracellular matrix in multiple sclerosis: an update. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 34: 603-9. PMID 11323746  0.32
2001 Encinas JA, Lees MB, Sobel RA, Symonowicz C, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis. International Immunology. 13: 257-64. PMID 11222494  0.32
2001 Clemons KV, Sobel RA, Williams PL, Stevens DA. Comparative toxicities and pharmacokinetics of intrathecal lipid (amphotericin B colloidal dispersion) and conventional deoxycholate formulations of amphotericin B in rabbits. Antimicrobial Agents and Chemotherapy. 45: 612-5. PMID 11158765 DOI: 10.1128/AAC.45.2.612-615.2001  0.32
2001 Sobel RA. Matrix metalloproteinases and diffuse white matter injury Stroke. 32: 1167-1168.  0.32
2000 Clemons KV, Grunig G, Sobel RA, Mirels LF, Rennick DM, Stevens DA. Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis. Clinical and Experimental Immunology. 122: 186-91. PMID 11091273 DOI: 10.1046/j.1365-2249.2000.01382.x  0.32
2000 Kuhns MS, Epshteyn V, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 12711-6. PMID 11050166 DOI: 10.1073/pnas.220423597  0.32
2000 Sorensen KN, Sobel RA, Clemons KV, Calderon L, Howell KJ, Irani PR, Pappagianis D, Williams PL, Stevens DA. Comparative efficacies of terbinafine and fluconazole in treatment of experimental coccidioidal meningitis in a rabbit model. Antimicrobial Agents and Chemotherapy. 44: 3087-91. PMID 11036027 DOI: 10.1128/AAC.44.11.3087-3091.2000  0.32
2000 Clemons KV, Darbonne WC, Curnutte JT, Sobel RA, Stevens DA. Experimental histoplasmosis in mice treated with anti-murine interferon-gamma antibody and in interferon-gamma gene knockout mice. Microbes and Infection / Institut Pasteur. 2: 997-1001. PMID 10967280 DOI: 10.1016/S1286-4579(00)01253-3  0.32
2000 Sobel RA. Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides. Journal of Neuroimmunology. 108: 45-52. PMID 10900336 DOI: 10.1016/S0165-5728(99)00270-2  0.32
2000 Sorensen KN, Sobel RA, Clemons KV, Pappagianis D, Stevens DA, Williams PL. Comparison of fluconazole and itraconazole in a rabbit model of coccidioidal meningitis. Antimicrobial Agents and Chemotherapy. 44: 1512-7. PMID 10817701 DOI: 10.1128/AAC.44.6.1512-1517.2000  0.32
2000 Waldner H, Whitters MJ, Sobel RA, Collins M, Kuchroo VK. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 3412-7. PMID 10737797 DOI: 10.1073/pnas.97.7.3412  0.32
2000 Smith-Norowitz TA, Sobel RA, Mokhtarian F. B cells and antibodies in the pathogenesis of myelin injury in Semliki Forest Virus encephalomyelitis. Cellular Immunology. 200: 27-35. PMID 10716880 DOI: 10.1006/cimm.2000.1613  0.32
2000 Clemons KV, Sobel RA, Stevens DA. Toxicity of LY303366, an echinocandin antifungal, in mice pretreated with glucocorticoids. Antimicrobial Agents and Chemotherapy. 44: 378-81. PMID 10639365 DOI: 10.1128/AAC.44.2.378-381.2000  0.32
1999 Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 190: 733-40. PMID 10477557 DOI: 10.1084/jem.190.5.733  0.32
1999 Adler H, Beland JL, Del-Pan NC, Kobzik L, Sobel RA, Rimm IJ. In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis. Journal of Neuroimmunology. 93: 208-13. PMID 10378885 DOI: 10.1016/S0165-5728(98)00236-7  0.32
1999 Beland JL, Sobel RA, Adler H, Del-Pan NC, Rimm IJ. B cell-deficient mice have increased susceptibility to HSV-1 encephalomyelitis and mortality. Journal of Neuroimmunology. 94: 122-6. PMID 10376944 DOI: 10.1016/S0165-5728(98)00238-0  0.32
1999 Mokhtarian F, Zhang Z, Shi Y, Gonzales E, Sobel RA. Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice. Journal of Neuroimmunology. 95: 43-54. PMID 10229114 DOI: 10.1016/S0165-5728(98)00254-9  0.32
1999 van der Maesen K, Hinojoza JR, Sobel RA. Endothelial cell class II major histocompatibility complex molecule expression in stereotactic brain biopsies of patients with acute inflammatory/demyelinating conditions. Journal of Neuropathology and Experimental Neurology. 58: 346-58. PMID 10218630  0.32
1999 Zhuo M, Zhang W, Son H, Mansuy I, Sobel RA, Seidman J, Kandel ER. A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 96: 4650-5. PMID 10200317 DOI: 10.1073/pnas.96.8.4650  0.32
1998 Williams PL, Sobel RA, Sorensen KN, Clemons KV, Shuer LM, Royaltey SS, Yao Y, Pappagianis D, Lutz JE, Reed C, River ME, Lee BC, Bhatti SU, Stevens DA. A model of coccidioidal meningoencephalitis and cerebrospinal vasculitis in the rabbit. The Journal of Infectious Diseases. 178: 1217-21. PMID 9806065  0.32
1998 Carrizosa AM, Nicholson LB, Farzan M, Southwood S, Sette A, Sobel RA, Kuchroo VK. Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen. Journal of Immunology (Baltimore, Md. : 1950). 161: 3307-14. PMID 9759846  0.32
1998 Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 161: 3299-306. PMID 9759845  0.32
1998 Sobel RA, Hinojoza JR, Maeda A, Chen M. Endothelial cell integrin laminin receptor expression in multiple sclerosis lesions. The American Journal of Pathology. 153: 405-15. PMID 9708801 DOI: 10.1016/S0002-9440(10)65584-8  0.32
1998 Sobel RA. The extracellular matrix in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 57: 205-17. PMID 9600212  0.32
1998 Santambrogio L, Lees MB, Sobel RA. Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS. Journal of Neuroimmunology. 81: 1-13. PMID 9521600 DOI: 10.1016/S0165-5728(97)00138-0  0.32
1998 Smith ME, van der Maesen K, Somera FP, Sobel RA. Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro. Neurochemical Research. 23: 427-34. PMID 9482257 DOI: 10.1023/A:1022478005243  0.32
1998 Sullivan TJ, Hurwitz AA, Sobel RA, Allison JP. Induction of CNS inflammatory disease as a consequence of CTLA-4/B7 blockade Faseb Journal. 12: A1092.  0.32
1997 Waldner H, Sobel RA, Howard E, Kuchroo VK. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 159: 3100-3. PMID 9317104  0.32
1997 Hevner R, Sobel RA. November 1996--premature baby with lethargy and coma. Brain Pathology (Zurich, Switzerland). 7: 839-40. PMID 9161734  0.32
1997 Greer JM, Klinguer C, Trifilieff E, Sobel RA, Lees MB. Encephalitogenicity of murine, but not bovine, DM20 in SJL mice is due to a single amino acid difference in the immunodominant encephalitogenic epitope. Neurochemical Research. 22: 541-7. PMID 9130268  0.32
1997 Brenner T, Brocke S, Szafer F, Sobel RA, Parkinson JF, Perez DH, Steinman L. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 158: 2940-6. PMID 9058833  0.32
1997 Hurwitz AA, Sullivan TJ, Krummel MF, Sobel RA, Allison JP. Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. Journal of Neuroimmunology. 73: 57-62. PMID 9058759 DOI: 10.1016/S0165-5728(96)00168-3  0.32
1996 Mokhtarian F, Wesselingh SL, Choi S, Maeda A, Griffin DE, Sobel RA, Grob D. Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. Journal of Neuroimmunology. 66: 11-22. PMID 8964904 DOI: 10.1016/0165-5728(95)00181-6  0.32
1996 Maeda A, Sobel RA. Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 55: 300-9. PMID 8786388  0.32
1996 Encinas JA, Lees MB, Sobel RA, Symonowicz C, Greer JM, Shovlin CL, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. Journal of Immunology (Baltimore, Md. : 1950). 157: 2186-92. PMID 8757345  0.32
1996 al-Sabbagh A, Nelson PA, Akselband Y, Sobel RA, Weiner HL. Antigen-driven peripheral immune tolerance: suppression of experimental autoimmmune encephalomyelitis and collagen-induced arthritis by aerosol administration of myelin basic protein or type II collagen. Cellular Immunology. 171: 111-9. PMID 8660845 DOI: 10.1006/cimm.1996.0180  0.32
1996 Greer JM, Sobel RA, Sette A, Southwood S, Lees MB, Kuchroo VK. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. Journal of Immunology (Baltimore, Md. : 1950). 156: 371-9. PMID 8598487  0.32
1996 Smith ME, Sobel RA. Effect of cytokines on phagocytic functions in macrophages and microglia Faseb Journal. 10: A1423.  0.32
1995 Sobel RA. The pathology of multiple sclerosis. Neurologic Clinics. 13: 1-21. PMID 7739499  0.32
1995 Nicholson LB, Greer JM, Sobel RA, Lees MB, Kuchroo VK. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity. 3: 397-405. PMID 7584131 DOI: 10.1016/1074-7613(95)90169-8  0.32
1995 Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6  0.32
1995 Sobel RA, Chen M, Maeda A, Hinojoza JR. Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 54: 202-13. PMID 7533209  0.32
1994 Kuchroo VK, Collins M, al-Sabbagh A, Sobel RA, Whitters MJ, Zamvil SS, Dorf ME, Hafler DA, Seidman JG, Weiner HL. T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. The Journal of Experimental Medicine. 179: 1659-64. PMID 8163944  0.32
1994 Gilles FH, Sobel EL, Leviton A, Tavaré CJ, Hedley-Whyte ET. Histologic feature reliability in childhood neural tumors. Childhood Brain Tumor Consortium. Journal of Neuropathology and Experimental Neurology. 53: 559-71. PMID 7964897  0.32
1994 Sobel RA, Greer JM, Kuchroo VK. Minireview: autoimmune responses to myelin proteolipid protein. Neurochemical Research. 19: 915-21. PMID 7528354 DOI: 10.1007/BF00968701  0.32
1994 Kuchroo VK, Greer JM, Kaul D, Ishioka G, Franco A, Sette A, Sobel RA, Lees MB. A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 153: 3326-36. PMID 7522258  0.32
1994 Sobel RA, Greer JM, Isaac J, Fondren G, Lees MB. Immunolocalization of proteolipid protein peptide 103-116 in myelin. Journal of Neuroscience Research. 37: 36-43. PMID 7511704 DOI: 10.1002/jnr.490370106  0.32
1993 Bell RB, Lindsey JW, Sobel RA, Hodgkinson S, Steinman L. Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 150: 4085-92. PMID 8473751  0.32
1993 Sobel RA. Vestibular (acoustic) schwannomas: histologic features in neurofibromatosis 2 and in unilateral cases. Journal of Neuropathology and Experimental Neurology. 52: 106-13. PMID 8440992  0.32
1993 Centeno BA, Louis DN, Kupsky WJ, Preffer FI, Sobel RA. The AgNOR technique, PCNA immunohistochemistry, and DNA ploidy in the evaluation of choroid plexus biopsy specimens. American Journal of Clinical Pathology. 100: 690-6. PMID 7902669  0.32
1993 Kuchroo VK, Martin CA, Greer JM, Ju ST, Sobel RA, Dorf ME. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 151: 4371-82. PMID 7691946  0.32
1993 Miller A, Zhang ZJ, Sobel RA, al-Sabbagh A, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. VI. Suppression of adoptively transferred disease and differential effects of oral vs. intravenous tolerization. Journal of Neuroimmunology. 46: 73-82. PMID 7689596 DOI: 10.1016/0165-5728(93)90235-Q  0.32
1992 Gilles FH, Sobel E, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman LS, Sobel RA. Epidemiology of seizures in children with brain tumors. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 12: 53-68. PMID 1541979 DOI: 10.1007/BF00172457  0.32
1992 Lee JK, Sobel RA, Chiocca EA, Kim TS, Martuza RL. Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. Journal of Neuro-Oncology. 14: 101-12. PMID 1432035 DOI: 10.1007/BF00177613  0.32
1992 Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA. Temporal trends among childhood brain tumor biopsies. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 13: 137-49. PMID 1432031 DOI: 10.1007/BF00172763  0.32
1992 Sobel RA, Kuchroo VK. The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions. Journal of Immunology (Baltimore, Md. : 1950). 149: 1444-51. PMID 1380045  0.32
1992 Greer JM, Kuchroo VK, Sobel RA, Lees MB. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. Journal of Immunology (Baltimore, Md. : 1950). 149: 783-8. PMID 1378866  0.32
1992 Tuohy VK, Sobel RA, Lu Z, Laursen RA, Lees MB. Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice. Journal of Neuroimmunology. 39: 67-74. PMID 1377711 DOI: 10.1016/0165-5728(92)90175-K  0.32
1992 Kuchroo VK, Sobel RA, Laning JC, Martin CA, Greenfield E, Dorf ME, Lees MB. Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. Journal of Immunology (Baltimore, Md. : 1950). 148: 3776-82. PMID 1376341  0.32
1992 Gruber ML, Sobel RA. A 45-year-old man with confusion, seizures, and few focal findings New England Journal of Medicine. 327: 107-116.  0.32
1991 Zamaroczy D, Schluesener HJ, Jolesz FA, Sobel RA, Colucci VM, Weiner HL, Sandor T. Differentiation of experimental white matter lesions using multiparametric magnetic resonance measurements. Investigative Radiology. 26: 317-24. PMID 2032819  0.32
1991 Louis DN, Hamilton AJ, Sobel RA, Ojemann RG. Pseudopsammomatous meningioma with elevated serum carcinoembryonic antigen: a true secretory meningioma. Case report. Journal of Neurosurgery. 74: 129-32. PMID 1984492 DOI: 10.3171/jns.1991.74.1.0129  0.32
1991 Halliday AL, Sobel RA, Martuza RL. Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2. Journal of Neurosurgery. 74: 248-53. PMID 1846409 DOI: 10.3171/jns.1991.74.2.0248  0.32
1991 Brod SA, al-Sabbagh A, Sobel RA, Hafler DA, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens: IV. Suppression of chronic relapsing disease in the Lewis rat and strain 13 guinea pig. Annals of Neurology. 29: 615-22. PMID 1716432 DOI: 10.1002/ana.410290608  0.32
1991 Sobel RA, Tuohy VK, Lees MB. Parental MHC molecule haplotype expression in (SJL/J x SWR)F1 mice with acute experimental allergic encephalomyelitis induced with two different synthetic peptides of myelin proteolipid protein. Journal of Immunology (Baltimore, Md. : 1950). 146: 543-9. PMID 1702806  0.32
1991 Samuels MA, Sobel RA. A 35-year-old man with changed mental status and multiple intracerebral lesions New England Journal of Medicine. 325: 414-422.  0.32
1991 Lees MB, Kuchroo VK, Sobel RA. Myelin proteolipid protein: Its role in experimental allergic encephalomyelitis International Pediatrics. 6: 84-90.  0.32
1991 Wen PY, Sobel RA. A 60-year-old man with multiple cerebral infarcts and cutaneous hemorrhagic lesions New England Journal of Medicine. 325: 714-726.  0.32
1991 Leifer D, Sobel RA. A 71-year-old woman with a sensorimotor neuropathy and radiographically demonstrable abnormalities New England Journal of Medicine. 325: 1723-1735.  0.32
1990 Sobel RA, Tuohy VK, Lu ZJ, Laursen RA, Lees MB. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. Journal of Neuropathology and Experimental Neurology. 49: 468-79. PMID 2273404  0.32
1990 Lampson LA, Kushner PD, Sobel RA. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Annals of Neurology. 28: 365-72. PMID 2241118 DOI: 10.1002/ana.410280311  0.32
1990 Hagler DA, Sobel RA. Case records of the Massachusetts General Hospital. A previously healthy 41-year-old man with meningoencephalitis and the rapid development of coma New England Journal of Medicine. 323: 1123-1135. PMID 2215581  0.32
1990 Sobel RA, Mitchell ME, Fondren G. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. The American Journal of Pathology. 136: 1309-16. PMID 1972610  0.32
1990 Lee JK, Choi B, Sobel RA, Chiocca EA, Martuza RL. Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. Journal of Neurosurgery. 73: 429-35. PMID 1696626 DOI: 10.3171/jns.1990.73.3.0429  0.32
1989 Sangruchi T, Sobel RA. Microglial and neural differentiation in human teratomas. Acta Neuropathologica. 78: 258-63. PMID 2763798 DOI: 10.1007/BF00687755  0.32
1989 Sobel RA, Mitchell ME. Fibronectin in multiple sclerosis lesions. The American Journal of Pathology. 135: 161-8. PMID 2528301  0.32
1989 Sobel RA. T-lymphocyte subsets in the multiple sclerosis lesion. Research in Immunology. 140: 208-11; discussion 2. PMID 2500682 DOI: 10.1016/0923-2494(89)90088-6  0.32
1989 Schluesener HJ, Lider O, Sobel RA. Induction of hyperacute brain inflammation and demyelination by activated encephalitogenic T cells and a monoclonal antibody specific for a myelin/oligodendrocyte glycoprotein. Autoimmunity. 2: 265-73. PMID 2491610 DOI: 10.3109/08916938909014690  0.32
1989 Medhkour A, Van Roey M, Sobel RA, Fingert HJ, Lee J, Martuza RL. Implantation of human meningiomas into the subrenal capsule of the nude mouse. A model for studies of tumor growth. Journal of Neurosurgery. 71: 545-50. PMID 2477514 DOI: 10.3171/jns.1989.71.4.0545  0.32
1989 Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. Journal of Immunology (Baltimore, Md. : 1950). 142: 1523-7. PMID 2465343  0.32
1989 Brown RH, Sobel RA. A 60-year-old man with granulomatous interstitial nephritis followed by neurologic disease New England Journal of Medicine. 321: 739-750.  0.32
1988 Tuohy VK, Sobel RA, Lees MB. Myelin proteolipid protein-induced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice. Journal of Immunology (Baltimore, Md. : 1950). 140: 1868-73. PMID 3257990  0.32
1988 Sobel RA, Ames MB. Major histocompatibility complex molecule expression in the human central nervous system: immunohistochemical analysis of 40 patients. Journal of Neuropathology and Experimental Neurology. 47: 19-28. PMID 3119782  0.32
1988 Sobel RA, Schneeberger EE, Colvin RB. The immunopathology of acute experimental allergic encephalomyelitis. V. A light microscopic and ultrastructural immunohistochemical analysis of fibronectin and fibrinogen. The American Journal of Pathology. 131: 547-58. PMID 2968050  0.32
1988 Sobel RA, Hafler DA, Castro EE, Morimoto C, Weiner HL. The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions. Journal of Immunology (Baltimore, Md. : 1950). 140: 2210-4. PMID 2965183  0.32
1988 Sobel RA, Hafler DA, Castro EE, Morimoto C, Weiner HL. Immunohistochemical analysis of suppressor-inducer and helper-inducer T cells in multiple sclerosis brain tissue. Annals of the New York Academy of Sciences. 540: 306-8. PMID 2905121  0.32
1988 Tuohy VK, Sobel RA, Lees MB. Susceptibility to PLP-induced EAE is regulated by non-H-2 genes. Annals of the New York Academy of Sciences. 540: 709-11. PMID 2462841  0.32
1988 Tuohy VK, Lu ZJ, Sobel RA, Laursen RA, Lees MB. A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 141: 1126-30. PMID 2456341  0.32
1988 Schluesener HJ, Sobel RA, Weiner HL. Demyelinating experimental allergic encephalomyelitis (EAE) in the rat: treatment with a monoclonal antibody against activated T cells. Journal of Neuroimmunology. 18: 341-51. PMID 2454946 DOI: 10.1016/0165-5728(88)90055-0  0.32
1988 Kowall NW, Sobel RA. A 27-year-old man with acute myelomonocytic leukemia in remission and repeated intracranial hemorrhages New England Journal of Medicine. 318: 427-440.  0.32
1988 Parker SW, Sobel RA. A 72-year-old man with headaches and multiple cranial-nerve palsies New England Journal of Medicine. 318: 760-768.  0.32
1987 Schluesener HJ, Sobel RA, Linington C, Weiner HL. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 139: 4016-21. PMID 3500978  0.32
1987 Sobel RA, Hanzakos JL, Blanchette BW, Williams AM, Dellapelle P, Colvin RB. Anti-T cell monoclonal antibodies in vivo. I. Inhibition of delayed hypersensitivity but not cutaneous basophil hypersensitivity reactions. Journal of Immunology (Baltimore, Md. : 1950). 138: 2500-6. PMID 3494071  0.32
1987 Gabuzda DH, Sobel RA. HIV antigen in brains of patients with AIDS. Annals of Neurology. 22: 668. PMID 3480698 DOI: 10.1002/ana.410220524  0.32
1986 Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Annals of Neurology. 20: 362-4. PMID 3639720 DOI: 10.1002/ana.410200316  0.32
1985 Sobel RA, Michaud J. Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma. Acta Neuropathologica. 68: 256-8. PMID 4082928 DOI: 10.1007/BF00690204  0.32
1984 Sobel RA, Ellis WG, Nielsen SL, Davis RL. Central nervous system coccidioidomycosis: a clinicopathologic study of treatment with and without amphotericin B. Human Pathology. 15: 980-95. PMID 6479976 DOI: 10.1016/S0046-8177(84)80128-8  0.32
1983 Hess JR, Michaud J, Sobel RA, Herman MM, Rubinstein LJ. The kinetics of human glioblastomas maintained in an organ culture system. An in vitro autoradiographic study. Acta Neuropathologica. 61: 1-9. PMID 6624382 DOI: 10.1007/BF00688379  0.32
1982 Ellis WG, Sobel RA, Nielsen SL. Leukoencephalopathy in patients treated with amphotericin B methyl ester. The Journal of Infectious Diseases. 146: 125-37. PMID 7108268  0.32
1981 Sobel RA, Trice JE, Nielsen SL, Ellis WG. Pineoblastoma with ganglionic and glial differentiation: report of two cases. Acta Neuropathologica. 55: 243-6. PMID 7349581 DOI: 10.1007/BF00691324  0.32
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