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Raymond A. Sobel, MD - Publications

Affiliations: 
Pathology Stanford University, Palo Alto, CA 
Area:
Cellular and molecular mechanisms of immune responses in the central nervous system; multiple sclerosis.
Website:
http://med.stanford.edu/profiles/neuroscience/faculty/Raymond_Sobel
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Year Citation  Score
2023 Sagan SA, Moinfar Z, Moseley CE, Dandekar R, Spencer CM, Verkman AS, Ottersen OP, Sobel RA, Sidney J, Sette A, Anderson MS, Steinman L, Wilson MR, Sabatino JJ, Zamvil SS. T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306572120. PMID 37463205 DOI: 10.1073/pnas.2306572120  0.31
2020 Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, et al. Checkpoint Receptor TIGIT Expressed on Tim-1 B Cells Regulates Tissue Inflammation. Cell Reports. 32: 107892. PMID 32668241 DOI: 10.1016/J.Celrep.2020.107892  0.356
2019 Sobel RA, Eaton MJ, Jaju PD, Lowry E, Hinojoza JR. Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation. Journal of Neuropathology and Experimental Neurology. 78: 819-843. PMID 31400116 DOI: 10.1093/Jnen/Nlz058  0.349
2019 Zhang X, Kiapour N, Kapoor S, Khan T, Thamilarasan M, Tao Y, Cohen S, Miller R, Sobel RA, Markovic-Plese S. IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 31341075 DOI: 10.4049/Jimmunol.1900311  0.331
2019 Graham KL, Werner BJ, Moyer KM, Patton AK, Krois CR, Yoo HS, Tverskoy M, LaJevic M, Napoli JL, Sobel RA, Zabel BA, Butcher EC. DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718413 DOI: 10.1073/Pnas.1817669116  0.405
2018 Meyer Zu Horste G, Przybylski D, Schramm MA, Wang C, Schnell A, Lee Y, Sobel R, Regev A, Kuchroo VK. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 48: 556-569.e7. PMID 29562202 DOI: 10.1016/J.Immuni.2018.03.008  0.371
2018 Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Sobel RA, Fukumura D, Jain RK, Anderson AC, Kuchroo VK, Joller N. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29500245 DOI: 10.4049/Jimmunol.1700407  0.365
2017 Krishnan B, Massilamany C, Basavalingappa RH, Gangaplara A, Rajasekaran RA, Afzal MZ, Khalilzad-Sharghi V, Zhou Y, Riethoven JJ, Nandi SS, Mishra PK, Sobel RA, Strande JL, Steffen D, Reddy J. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 29229678 DOI: 10.4049/Jimmunol.1701090  0.413
2017 Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS. Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. Journal of Visualized Experiments : Jove. PMID 28872108 DOI: 10.3791/56185  0.429
2016 Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, ... Sobel RA, et al. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940915 DOI: 10.1073/Pnas.1617859114  0.435
2016 Basavalingappa RH, Massilamany C, Krishnan B, Gangaplara A, Kang G, Khalilzad-Sharghi V, Han Z, Othman S, Li Q, Riethoven JJ, Sobel RA, Steffen D, Reddy J. Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice. The American Journal of Pathology. 186: 3160-3175. PMID 27876151 DOI: 10.1016/J.Ajpath.2016.08.005  0.364
2016 Varrin-Doyer M, Pekarek KL, Spencer CM, Bernard CC, Sobel RA, Cree BA, Schulze-Topphoff U, Zamvil SS. Treatment of spontaneous EAE by laquinimod reduces Tfh, B cell aggregates, and disease progression. Neurology(R) Neuroimmunology & Neuroinflammation. 3: e272. PMID 27704036 DOI: 10.1212/Nxi.0000000000000272  0.354
2016 McArdel SL, Brown DR, Sobel RA, Sharpe AH. Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27581174 DOI: 10.4049/Jimmunol.1600706  0.307
2016 Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain : a Journal of Neurology. PMID 27246324 DOI: 10.1093/Brain/Aww113  0.405
2016 Schulze-Topphoff U, Varrin-Doyer M, Pekarek K, Spencer CM, Shetty A, Sagan SA, Cree BA, Sobel RA, Wipke BT, Steinman L, Scannevin RH, Zamvil SS. Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27078105 DOI: 10.1073/Pnas.1603907113  0.404
2016 Lehmann-Horn K, Sagan SA, Winger RC, Spencer CM, Bernard CC, Sobel RA, Zamvil SS. CNS accumulation of regulatory B cells is VLA-4-dependent. Neurology® Neuroimmunology & Neuroinflammation. 3: e212. PMID 27027096 DOI: 10.1212/Nxi.0000000000000212  0.41
2015 Wang C, Yosef N, Gaublomme J, Wu C, Lee Y, Clish CB, Kaminski J, Xiao S, Zu Horste GM, Pawlak M, Kishi Y, Joller N, Karwacz K, Zhu C, Ordovas-Montanes M, ... ... Sobel RA, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. PMID 26607793 DOI: 10.1016/J.Cell.2015.10.068  0.334
2015 Lee Y, Mitsdoerffer M, Xiao S, Gu G, Sobel RA, Kuchroo VK. IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. PMID 26413871 DOI: 10.1172/Jci75933  0.337
2015 Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH. Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. The Journal of Experimental Medicine. 212: 1603-21. PMID 26371185 DOI: 10.1084/Jem.20141030  0.384
2015 Lehmann-Horn K, Sagan SA, Bernard CC, Sobel RA, Zamvil SS. B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity. Annals of Neurology. 77: 902-8. PMID 25712734 DOI: 10.1002/Ana.24387  0.389
2015 Xiao S, Brooks CR, Sobel RA, Kuchroo VK. Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 1602-8. PMID 25582854 DOI: 10.4049/Jimmunol.1402632  0.329
2015 Peters A, Burkett PR, Sobel RA, Buckley CD, Watson SP, Bettelli E, Kuchroo VK. Podoplanin negatively regulates CD4+ effector T cell responses. The Journal of Clinical Investigation. 125: 129-40. PMID 25415436 DOI: 10.1172/Jci74685  0.403
2014 Graham KL, Zhang JV, Lewén S, Burke TM, Dang T, Zoudilova M, Sobel RA, Butcher EC, Zabel BA. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. Plos One. 9: e112925. PMID 25437209 DOI: 10.1371/Journal.Pone.0112925  0.424
2014 Shetty A, Gupta SG, Varrin-Doyer M, Weber MS, Prod'homme T, Molnarfi N, Ji N, Nelson PA, Patarroyo JC, Schulze-Topphoff U, Fogal SE, Forsthuber T, Sobel RA, Bernard CC, Slavin AJ, et al. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology® Neuroimmunology & Neuroinflammation. 1: e22. PMID 25340074 DOI: 10.1212/Nxi.0000000000000022  0.365
2014 Massilamany C, Marciano-Cabral F, Rocha-Azevedo Bd, Jamerson M, Gangaplara A, Steffen D, Zabad R, Illes Z, Sobel RA, Reddy J. SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens. Plos One. 9: e98506. PMID 24879066 DOI: 10.1371/Journal.Pone.0098506  0.425
2014 Wang D, Bhat R, Sobel RA, Huang W, Wang LX, Olsson T, Steinman L. Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug Development Research. 75: 172-88. PMID 24648292 DOI: 10.1002/Ddr.21169  0.371
2014 Varrin-doyer M, Topphoff US, Pekarek K, Sobel RA, Zamvil SS. Laquinimod prevents disability progression in a model of spontaneous chronic EAE and interferes with development of follicular helper T cells Journal of Neuroimmunology. 275: 209. DOI: 10.1016/J.Jneuroim.2014.08.562  0.344
2013 Molnarfi N, Schulze-Topphoff U, Weber MS, Patarroyo JC, Prod'homme T, Varrin-Doyer M, Shetty A, Linington C, Slavin AJ, Hidalgo J, Jenne DE, Wekerle H, Sobel RA, Bernard CC, Shlomchik MJ, et al. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. The Journal of Experimental Medicine. 210: 2921-37. PMID 24323356 DOI: 10.1084/Jem.20130699  0.414
2013 Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, et al. Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nature Immunology. 14: 1166-72. PMID 24076635 DOI: 10.1038/Ni.2730  0.33
2013 Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Pekarek K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. The Journal of Experimental Medicine. 210: 1301-9. PMID 23797093 DOI: 10.1084/Jem.20121611  0.437
2012 Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9. PMID 22961052 DOI: 10.1038/Ni.2416  0.35
2012 Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, et al. Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. Nature Medicine. 18: 1394-400. PMID 22863785 DOI: 10.1038/Nm.2871  0.405
2012 Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 12105-10. PMID 22773818 DOI: 10.1073/Pnas.1120914109  0.36
2012 Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, ... ... Sobel RA, et al. Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. The Journal of Experimental Medicine. 209: 1325-34. PMID 22734047 DOI: 10.1084/Jem.20101974  0.366
2012 Schulze-Topphoff U, Shetty A, Varrin-Doyer M, Molnarfi N, Sagan SA, Sobel RA, Nelson PA, Zamvil SS. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. Plos One. 7: e33797. PMID 22479444 DOI: 10.1371/Journal.Pone.0033797  0.45
2012 Anderson AC, Chandwaskar R, Lee DH, Sullivan JM, Solomon A, Rodriguez-Manzanet R, Greve B, Sobel RA, Kuchroo VK. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2084-92. PMID 22279107 DOI: 10.4049/Jimmunol.1102186  0.402
2012 Shetty A, Gupta S, Weber M, Molnarfi N, Forsthuber T, Sobel R, Bernard C, Slavin A, Zamvil S. T Cell Epitope 119-132, but Not 35-55, Is the Immunodominant Encephalitogenic Determinant of the CNS Autoantigen, Myelin Oligodendrocyte Glycoprotein (P05.118) Neurology. 78: P05.118-P05.118. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.118  0.396
2012 Nelson P, Varrin-Doyer M, Spencer C, Sagan S, Boyd C, Sobel R, Bennett J, Zamvil S. Aquaporin-4 Peptide-Specific T Cells Induce CNS Inflammation (P02.134) Neurology. 78: P02.134-P02.134. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.134  0.347
2012 Schulze Topphoff U, Shetty A, Varrin-Doyer M, Molnarfi N, Sagan S, Sobel R, Nelson P, Zamvil S. Laquinimod Promotes T Cell Immune Modulation in Central Nervous System Autoimmunity Via Type II (M2) Myeloid APC (P02.105) Neurology. 78: P02.105-P02.105. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.105  0.443
2011 Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity. 35: 986-96. PMID 22177922 DOI: 10.1016/J.Immuni.2011.10.015  0.4
2011 Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. Journal of Clinical Immunology. 31: 1010-20. PMID 21847523 DOI: 10.1007/S10875-011-9579-6  0.378
2010 Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A, Nguyen K, Mukundan L, Moshkova M, Dugas JC, Chawla A, Steinman L. Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. The Journal of Experimental Medicine. 207: 1599-608. PMID 20624891 DOI: 10.1084/Jem.20091663  0.386
2010 Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, Cornejo M, Nishi N, Yamauchi A, Quintana FJ, Sobel RA, Hirashima M, Kuchroo VK. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 1383-92. PMID 20574007 DOI: 10.4049/Jimmunol.0903275  0.371
2010 Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radical Biology & Medicine. 48: 1501-12. PMID 20188820 DOI: 10.1016/J.Freeradbiomed.2010.02.028  0.312
2009 Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. Journal of Immunology (Baltimore, Md. : 1950). 183: 7169-77. PMID 19890056 DOI: 10.4049/Jimmunol.0901906  0.403
2009 Graham KL, Zabel BA, Loghavi S, Zuniga LA, Ho PP, Sobel RA, Butcher EC. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 6717-23. PMID 19864606 DOI: 10.4049/Jimmunol.0803435  0.418
2009 Araki M, Chung D, Liu S, Rainbow DB, Chamberlain G, Garner V, Hunter KM, Vijayakrishnan L, Peterson LB, Oukka M, Sharpe AH, Sobel R, Kuchroo VK, Wicker LS. Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5146-57. PMID 19783679 DOI: 10.4049/Jimmunol.0802610  0.336
2009 Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14948-53. PMID 19706421 DOI: 10.1073/Pnas.0903958106  0.388
2008 Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nature Immunology. 9: 1347-55. PMID 18997793 DOI: 10.1038/Ni.1677  0.331
2008 Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 expressed on APCs induces T cell expansion and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 4706-13. PMID 18354194 DOI: 10.4049/Jimmunol.180.7.4706  0.37
2008 Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 451: 1076-81. PMID 18278032 DOI: 10.1038/Nature06559  0.332
2007 Illés Z, Waldner H, Reddy J, Anderson AC, Sobel RA, Kuchroo VK. Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background. International Immunology. 19: 1235-48. PMID 17804690 DOI: 10.1093/Intimm/Dxm094  0.388
2007 Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, Patarroyo JC, Stüve O, Sobel RA, Steinman L, Zamvil SS. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nature Medicine. 13: 935-43. PMID 17676050 DOI: 10.1038/Nm1620  0.406
2007 Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. The Journal of Experimental Medicine. 204: 1691-702. PMID 17606630 DOI: 10.1084/Jem.20062498  0.371
2007 Greve B, Weissert R, Hamdi N, Bettelli E, Sobel RA, Coyle A, Kuchroo VK, Rajewsky K, Schmidt-Supprian M. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 179-85. PMID 17579036 DOI: 10.4049/Jimmunol.179.1.179  0.424
2007 Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'Connor KC, Hafler DA, Sobel RA, Robinson WH, Steinman L. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature. 448: 474-9. PMID 17568699 DOI: 10.1038/Nature05935  0.431
2007 Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nature Medicine. 13: 423-31. PMID 17384649 DOI: 10.1038/Nm1564  0.412
2007 Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. The Journal of Experimental Medicine. 204: 321-30. PMID 17261635 DOI: 10.1084/Jem.20061839  0.382
2007 Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. The Journal of Clinical Investigation. 117: 438-47. PMID 17256058 DOI: 10.1172/Jci28844  0.387
2007 Sobel RA. Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse? The American Journal of Pathology. 170: 436-8. PMID 17255311 DOI: 10.2353/Ajpath.2007.061098  0.428
2007 Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nature Immunology. 8: 74-83. PMID 17143274 DOI: 10.1038/Ni1415  0.395
2007 Lee L, Burge M, Ho P, Sobel R, Shizuru J. Purified MHC-Matched Hematopoietic Stem Cell Transplantation Following Total Lymphoid Irradiation and Anti-Thymocyte Globulin (TLI+ATG) Blocks EAE Pathogenesis. Blood. 110: 3259-3259. DOI: 10.1182/Blood.V110.11.3259.3259  0.396
2007 Manzanet RR, Hartt-Meyers J, Slavik J, Dardalhon V, Kassam N, Greenfield EA, Sobel RA, Strom TB, Hafler DA, Kuchroo VK. Tim-4 Expressed on Antigen-presenting Cells Induces T Cell Expansion and Survival Clinical Immunology. 123: S124-S125. DOI: 10.1016/J.Clim.2007.03.533  0.354
2007 Dunn S, Ousman S, Sobel R, Baranzini S, Zuniga L, Youssef S, Oksenberg J, Steinman L. Peroxisome Poliferator-activated Receptor-α (PPARα) Expression in T Cells Mediates Gender Differences in Development of T Cell-mediated Autoimmunity Clinical Immunology. 123: S74. DOI: 10.1016/J.Clim.2007.03.390  0.343
2007 Korn T, Oukka M, Reddy J, Bettelli E, Awasthi A, Sobel R, Wucherpfennig K, Kuchroo V. Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation Clinical Immunology. 123: S152-S153. DOI: 10.1016/J.Clim.2007.03.073  0.402
2006 Bettelli E, Baeten D, Jäger A, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of Clinical Investigation. 116: 2393-402. PMID 16955141 DOI: 10.1172/Jci28334  0.418
2006 Waldner H, Sobel RA, Price N, Kuchroo VK. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 5455-62. PMID 16622013 DOI: 10.4049/Jimmunol.176.9.5455  0.35
2006 Stüve O, Youssef S, Weber MS, Nessler S, von Büdingen HC, Hemmer B, Prod'homme T, Sobel RA, Steinman L, Zamvil SS. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. The Journal of Clinical Investigation. 116: 1037-44. PMID 16543951 DOI: 10.1172/Jci25805  0.338
2006 Greenfield EA, Reddy J, Lees A, Dyer CA, Koul O, Nguyen K, Bell S, Kassam N, Hinojoza J, Eaton MJ, Lees MB, Kuchroo VK, Sobel RA. Monoclonal antibodies to distinct regions of human myelin proteolipid protein simultaneously recognize central nervous system myelin and neurons of many vertebrate species. Journal of Neuroscience Research. 83: 415-31. PMID 16416423 DOI: 10.1002/Jnr.20748  0.311
2006 Kanter JL, Narayana S, Ho PP, Catz I, Warren KG, Sobel RA, Steinman L, Robinson WH. Lipid microarrays identify key mediators of autoimmune brain inflammation. Nature Medicine. 12: 138-43. PMID 16341241 DOI: 10.1038/Nm1344  0.359
2006 Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Anderson A, Zhang Z, Gutierrez C, Sobel R, Umetsu D, Yagita H, Akiba H, Sayegh M, DeKruyff R, Khoury S, et al. TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity Clinical Immunology. 119: S44-S45. DOI: 10.1016/J.Clim.2006.04.412  0.341
2005 Miyamoto K, Kingsley CI, Zhang X, Jabs C, Izikson L, Sobel RA, Weiner HL, Kuchroo VK, Sharpe AH. The ICOS molecule plays a crucial role in the development of mucosal tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 7341-7. PMID 16301640 DOI: 10.4049/Jimmunol.175.11.7341  0.41
2005 Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science (New York, N.Y.). 310: 850-5. PMID 16272121 DOI: 10.1126/Science.1117634  0.403
2005 Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, et al. A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 175: 6226-34. PMID 16237121 DOI: 10.4049/Jimmunol.175.9.6226  0.327
2005 Reddy J, Waldner H, Zhang X, Illes Z, Wucherpfennig KW, Sobel RA, Kuchroo VK. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 5591-5. PMID 16237044 DOI: 10.4049/Jimmunol.175.9.5591  0.379
2005 Zhang Y, Da RR, Hilgenberg LG, Tourtellotte WW, Sobel RA, Smith MA, Olek M, Nagra R, Sudhir G, van den Noort S, Qin Y. Clonal expansion of IgA-positive plasma cells and axon-reactive antibodies in MS lesions. Journal of Neuroimmunology. 167: 120-30. PMID 16099056 DOI: 10.1016/J.Jneuroim.2005.05.006  0.314
2005 Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Tim-2 regulates T helper type 2 responses and autoimmunity. The Journal of Experimental Medicine. 202: 437-44. PMID 16043519 DOI: 10.1084/Jem.20050308  0.379
2005 Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. Journal of Immunology (Baltimore, Md. : 1950). 175: 1558-65. PMID 16034094 DOI: 10.4049/Jimmunol.175.3.1558  0.332
2005 Zhang Y, Da RR, Guo W, Ren HM, Hilgenberg LG, Sobel RA, Tourtellotte WW, Smith MA, Olek M, Gupta S, Robertson RT, Nagra R, Van Den Noort S, Qin Y. Axon reactive B cells clonally expanded in the cerebrospinal fluid of patients with multiple sclerosis. Journal of Clinical Immunology. 25: 254-64. PMID 15981091 DOI: 10.1007/S10875-005-4083-5  0.311
2004 Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L. Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 6981-92. PMID 15557195 DOI: 10.4049/Jimmunol.173.11.6981  0.394
2004 Reddy J, Illes Z, Zhang X, Encinas J, Pyrdol J, Nicholson L, Sobel RA, Wucherpfennig KW, Kuchroo VK. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15434-9. PMID 15492218 DOI: 10.1073/Pnas.0404444101  0.367
2004 Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, Kuchroo VK, Freeman GJ, Sharpe AH. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 10691-6. PMID 15249675 DOI: 10.1073/Pnas.0307252101  0.309
2004 Anderson AC, Reddy J, Nazareno R, Sobel RA, Nicholson LB, Kuchroo VK. IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 828-34. PMID 15240669 DOI: 10.4049/Jimmunol.173.2.828  0.407
2004 Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/Jem.20031819  0.414
2004 Greve B, Reddy J, Waldner HP, Sobel RA, Kuchroo VK. Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes. European Journal of Immunology. 34: 1828-38. PMID 15214031 DOI: 10.1002/Eji.200425116  0.365
2004 Greve B, Vijayakrishnan L, Kubal A, Sobel RA, Peterson LB, Wicker LS, Kuchroo VK. The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 157-63. PMID 15210770 DOI: 10.4049/Jimmunol.173.1.157  0.376
2004 Maffei CM, Mirels LF, Sobel RA, Clemons KV, Stevens DA. Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis. Infection and Immunity. 72: 2338-49. PMID 15039359 DOI: 10.1128/Iai.72.4.2338-2349.2004  0.325
2004 Klein RS, Izikson L, Means T, Gibson HD, Lin E, Sobel RA, Weiner HL, Luster AD. IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 172: 550-9. PMID 14688366 DOI: 10.4049/Jimmunol.172.1.550  0.432
2003 Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. European Journal of Immunology. 33: 2022-2032. PMID 12884869 DOI: 10.1002/Eji.200323180  0.369
2003 Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of Experimental Medicine. 197: 1073-81. PMID 12732654 DOI: 10.1084/Jem.20021603  0.38
2003 Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, Madanat R, Garren H, Fontoura P, Tsai M, Galli SJ, Sobel RA, Steinman L. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proceedings of the National Academy of Sciences of the United States of America. 100: 1867-72. PMID 12576552 DOI: 10.1073/Pnas.252777399  0.386
2003 Kamberi P, Sobel RA, Clemons KV, Stevens DA, Pappagianis D, Williams PL. A murine model of coccidioidal meningitis. The Journal of Infectious Diseases. 187: 453-60. PMID 12552429 DOI: 10.1086/367961  0.304
2002 Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420: 78-84. PMID 12422218 DOI: 10.1038/Nature01158  0.396
2002 Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. European Journal of Immunology. 32: 2687-97. PMID 12207354 DOI: 10.1002/1521-4141(200209)32:9<2687::Aid-Immu2687>3.0.Co;2-1  0.322
2002 Chiller TM, Luque JC, Sobel RA, Farrokhshad K, Clemons KV, Stevens DA. Development of a murine model of cerebral aspergillosis. The Journal of Infectious Diseases. 186: 574-7. PMID 12195389 DOI: 10.1086/341567  0.334
2002 Kuruganti PA, Hinojoza JR, Eaton MJ, Ehmann UK, Sobel RA. Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 61: 710-24. PMID 12152786 DOI: 10.1093/Jnen/61.8.710  0.332
2002 Hurwitz AA, Sullivan TJ, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 3013-7. PMID 11867713 DOI: 10.1073/Pnas.042684699  0.42
2002 Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 415: 536-41. PMID 11823861 DOI: 10.1038/415536A  0.391
2001 Sobel RA, Ahmed AS. White matter extracellular matrix chondroitin sulfate/dermatan sulfate proteoglycans in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 60: 1198-207. PMID 11764092 DOI: 10.1093/Jnen/60.12.1198  0.326
2001 Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (New York, N.Y.). 294: 1731-5. PMID 11721059 DOI: 10.1126/Science.1062960  0.405
2001 Greer JM, Denis B, Sobel RA, Trifilieff E. Thiopalmitoylation of myelin proteolipid protein epitopes enhances immunogenicity and encephalitogenicity. Journal of Immunology (Baltimore, Md. : 1950). 166: 6907-13. PMID 11359852 DOI: 10.4049/Jimmunol.166.11.6907  0.362
2001 Encinas JA, Lees MB, Sobel RA, Symonowicz C, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis. International Immunology. 13: 257-64. PMID 11222494 DOI: 10.1093/Intimm/13.3.257  0.312
2000 Clemons KV, Grunig G, Sobel RA, Mirels LF, Rennick DM, Stevens DA. Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis. Clinical and Experimental Immunology. 122: 186-91. PMID 11091273 DOI: 10.1046/J.1365-2249.2000.01382.X  0.301
2000 Kuhns MS, Epshteyn V, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 12711-6. PMID 11050166 DOI: 10.1073/Pnas.220423597  0.387
2000 Clemons KV, Darbonne WC, Curnutte JT, Sobel RA, Stevens DA. Experimental histoplasmosis in mice treated with anti-murine interferon-gamma antibody and in interferon-gamma gene knockout mice. Microbes and Infection / Institut Pasteur. 2: 997-1001. PMID 10967280 DOI: 10.1016/S1286-4579(00)01253-3  0.317
2000 Sobel RA. Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides. Journal of Neuroimmunology. 108: 45-52. PMID 10900336 DOI: 10.1016/S0165-5728(99)00270-2  0.336
2000 Waldner H, Whitters MJ, Sobel RA, Collins M, Kuchroo VK. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 3412-7. PMID 10737797 DOI: 10.1073/Pnas.97.7.3412  0.422
2000 Smith-Norowitz TA, Sobel RA, Mokhtarian F. B cells and antibodies in the pathogenesis of myelin injury in Semliki Forest Virus encephalomyelitis. Cellular Immunology. 200: 27-35. PMID 10716880 DOI: 10.1006/Cimm.2000.1613  0.382
1999 Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 190: 733-40. PMID 10477557 DOI: 10.1084/Jem.190.5.733  0.392
1999 Adler H, Beland JL, Del-Pan NC, Kobzik L, Sobel RA, Rimm IJ. In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis. Journal of Neuroimmunology. 93: 208-13. PMID 10378885 DOI: 10.1016/S0165-5728(98)00236-7  0.377
1999 Beland JL, Sobel RA, Adler H, Del-Pan NC, Rimm IJ. B cell-deficient mice have increased susceptibility to HSV-1 encephalomyelitis and mortality. Journal of Neuroimmunology. 94: 122-6. PMID 10376944 DOI: 10.1016/S0165-5728(98)00238-0  0.35
1999 Mokhtarian F, Zhang Z, Shi Y, Gonzales E, Sobel RA. Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice. Journal of Neuroimmunology. 95: 43-54. PMID 10229114 DOI: 10.1016/S0165-5728(98)00254-9  0.348
1999 van der Maesen K, Hinojoza JR, Sobel RA. Endothelial cell class II major histocompatibility complex molecule expression in stereotactic brain biopsies of patients with acute inflammatory/demyelinating conditions. Journal of Neuropathology and Experimental Neurology. 58: 346-58. PMID 10218630 DOI: 10.1097/00005072-199904000-00005  0.337
1998 Carrizosa AM, Nicholson LB, Farzan M, Southwood S, Sette A, Sobel RA, Kuchroo VK. Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen. Journal of Immunology (Baltimore, Md. : 1950). 161: 3307-14. PMID 9759846 DOI: 10.1016/S0165-5728(98)91376-5  0.368
1998 Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 161: 3299-306. PMID 9759845 DOI: 10.1016/S0165-5728(98)91500-4  0.313
1998 Sobel RA. The extracellular matrix in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 57: 205-17. PMID 9600212 DOI: 10.1097/00005072-199803000-00001  0.324
1998 Santambrogio L, Lees MB, Sobel RA. Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS. Journal of Neuroimmunology. 81: 1-13. PMID 9521600 DOI: 10.1016/S0165-5728(97)00138-0  0.396
1998 Smith ME, van der Maesen K, Somera FP, Sobel RA. Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro. Neurochemical Research. 23: 427-34. PMID 9482257 DOI: 10.1023/A:1022478005243  0.318
1998 Mokhtarian F, Sobel R, Zhang Z, Shi Y, Gonzales E. Molecular mimicry between a viral peptide and a myelin peptide induced autoimmune demyelinating disease in mice Journal of Neuroimmunology. 90: 36. DOI: 10.1016/S0165-5728(98)91394-7  0.309
1997 Gilles FH, Sobel EL, Leviton A, Tavaré CJ, Hedley-Whyte ET, Rorke L, Adelman L, Sobel R. Quantitative histologic factors for grouping childhood infratentorial neuroglial tumors. Pediatric Pathology & Laboratory Medicine : Journal of the Society For Pediatric Pathology, Affiliated With the International Paediatric Pathology Association. 17: 809-34. PMID 9267891 DOI: 10.1080/107710497174499  0.43
1997 Greer JM, Klinguer C, Trifilieff E, Sobel RA, Lees MB. Encephalitogenicity of murine, but not bovine, DM20 in SJL mice is due to a single amino acid difference in the immunodominant encephalitogenic epitope. Neurochemical Research. 22: 541-7. PMID 9130268 DOI: 10.1023/A:1027336516785  0.339
1997 Hurwitz AA, Sullivan TJ, Krummel MF, Sobel RA, Allison JP. Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. Journal of Neuroimmunology. 73: 57-62. PMID 9058759 DOI: 10.1016/S0165-5728(96)00168-3  0.352
1996 Mokhtarian F, Wesselingh SL, Choi S, Maeda A, Griffin DE, Sobel RA, Grob D. Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. Journal of Neuroimmunology. 66: 11-22. PMID 8964904 DOI: 10.1016/0165-5728(95)00181-6  0.362
1996 al-Sabbagh A, Nelson PA, Akselband Y, Sobel RA, Weiner HL. Antigen-driven peripheral immune tolerance: suppression of experimental autoimmmune encephalomyelitis and collagen-induced arthritis by aerosol administration of myelin basic protein or type II collagen. Cellular Immunology. 171: 111-9. PMID 8660845 DOI: 10.1006/Cimm.1996.0180  0.375
1995 Sobel RA. The pathology of multiple sclerosis. Neurologic Clinics. 13: 1-21. PMID 7739499 DOI: 10.1016/S0733-8619(18)30059-8  0.354
1995 Nicholson LB, Greer JM, Sobel RA, Lees MB, Kuchroo VK. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity. 3: 397-405. PMID 7584131 DOI: 10.1016/1074-7613(95)90169-8  0.369
1995 Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6  0.356
1995 Sobel RA, Chen M, Maeda A, Hinojoza JR. Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 54: 202-13. PMID 7533209 DOI: 10.1097/00005072-199503000-00007  0.325
1994 Kuchroo VK, Collins M, al-Sabbagh A, Sobel RA, Whitters MJ, Zamvil SS, Dorf ME, Hafler DA, Seidman JG, Weiner HL. T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. The Journal of Experimental Medicine. 179: 1659-64. PMID 8163944 DOI: 10.1084/Jem.179.5.1659  0.433
1994 Sobel RA, Greer JM, Kuchroo VK. Minireview: autoimmune responses to myelin proteolipid protein. Neurochemical Research. 19: 915-21. PMID 7528354 DOI: 10.1007/Bf00968701  0.373
1993 Centeno BA, Louis DN, Kupsky WJ, Preffer FI, Sobel RA. The AgNOR technique, PCNA immunohistochemistry, and DNA ploidy in the evaluation of choroid plexus biopsy specimens. American Journal of Clinical Pathology. 100: 690-6. PMID 7902669 DOI: 10.1093/Ajcp/100.6.690  0.45
1993 Miller A, Zhang ZJ, Sobel RA, al-Sabbagh A, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. VI. Suppression of adoptively transferred disease and differential effects of oral vs. intravenous tolerization. Journal of Neuroimmunology. 46: 73-82. PMID 7689596 DOI: 10.1016/0165-5728(93)90235-Q  0.352
1993 Abromson-Leeman S, Hayashi M, Martin C, Sobel R, al-Sabbagh A, Weiner H, Dorf ME. T cell responses to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice. Journal of Neuroimmunology. 45: 89-101. PMID 7687253 DOI: 10.1016/0165-5728(93)90168-X  0.433
1993 Greer J, Kuchroo V, Sobel R, Lees M. A second encephalitogenic PLP epitope for SJL mice Journal of Neuroimmunology. 43: 206. DOI: 10.1016/0165-5728(93)90108-B  0.308
1992 Gilles FH, Sobel E, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman LS, Sobel RA. Epidemiology of seizures in children with brain tumors. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 12: 53-68. PMID 1541979 DOI: 10.1007/Bf00172457  0.476
1992 Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA. Temporal trends among childhood brain tumor biopsies. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 13: 137-49. PMID 1432031 DOI: 10.1007/Bf00172763  0.493
1992 Tuohy VK, Sobel RA, Lu Z, Laursen RA, Lees MB. Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice. Journal of Neuroimmunology. 39: 67-74. PMID 1377711 DOI: 10.1016/0165-5728(92)90175-K  0.344
1991 Zamaroczy D, Schluesener HJ, Jolesz FA, Sobel RA, Colucci VM, Weiner HL, Sandor T. Differentiation of experimental white matter lesions using multiparametric magnetic resonance measurements. Investigative Radiology. 26: 317-24. PMID 2032819 DOI: 10.1097/00004424-199104000-00007  0.321
1991 Louis DN, Hamilton AJ, Sobel RA, Ojemann RG. Pseudopsammomatous meningioma with elevated serum carcinoembryonic antigen: a true secretory meningioma. Case report. Journal of Neurosurgery. 74: 129-32. PMID 1984492 DOI: 10.3171/Jns.1991.74.1.0129  0.464
1991 Weiner HL, Zhang ZJ, Khoury SJ, Miller A, al-Sabbagh A, Brod SA, Lider O, Higgins P, Sobel R, Nussenblatt RB. Antigen-driven peripheral immune tolerance. Suppression of organ-specific autoimmune diseases by oral administration of autoantigens. Annals of the New York Academy of Sciences. 636: 227-32. PMID 1793212 DOI: 10.1111/J.1749-6632.1991.Tb33454.X  0.309
1991 Kuchroo VK, Sobel RA, Yamamura T, Greenfield E, Dorf ME, Lees MB. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 59: 305-12. PMID 1716908 DOI: 10.1159/000163668  0.362
1991 Brod SA, al-Sabbagh A, Sobel RA, Hafler DA, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens: IV. Suppression of chronic relapsing disease in the Lewis rat and strain 13 guinea pig. Annals of Neurology. 29: 615-22. PMID 1716432 DOI: 10.1002/Ana.410290608  0.358
1991 Kuchroo VK, Sobel RA, Laning JC, Greenfield E, Ju S, Dorf ME, Lees MB. Heterogeneity of T cell clones specific for an encephalitogenic determinant of myelin proteolipid protein (PLP) Journal of Neuroimmunology. 35: 44. DOI: 10.1016/0165-5728(91)90913-R  0.366
1991 Sobel RA, Kuchroo VK, Wang Y, Dorf ME, Lees MB. Heterogeneous T cell receptor (TcR) Vβs of acute experimental allergic encephalomyelitis (EAE) induced with a myelin proteolipid protein (PLP) peptide and peptide-specific T cell clones Journal of Neuroimmunology. 35: 43. DOI: 10.1016/0165-5728(91)90912-Q  0.359
1990 Sobel RA, Tuohy VK, Lu ZJ, Laursen RA, Lees MB. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. Journal of Neuropathology and Experimental Neurology. 49: 468-79. PMID 2273404 DOI: 10.1097/00005072-199009000-00002  0.367
1990 Lampson LA, Kushner PD, Sobel RA. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Annals of Neurology. 28: 365-72. PMID 2241118 DOI: 10.1002/Ana.410280311  0.36
1989 Sobel RA. T-lymphocyte subsets in the multiple sclerosis lesion. Research in Immunology. 140: 208-11; discussion 2. PMID 2500682 DOI: 10.1016/0923-2494(89)90088-6  0.327
1989 Schluesener HJ, Lider O, Sobel RA. Induction of hyperacute brain inflammation and demyelination by activated encephalitogenic T cells and a monoclonal antibody specific for a myelin/oligodendrocyte glycoprotein. Autoimmunity. 2: 265-73. PMID 2491610 DOI: 10.3109/08916938909014690  0.387
1988 Sobel RA, Ames MB. Major histocompatibility complex molecule expression in the human central nervous system: immunohistochemical analysis of 40 patients. Journal of Neuropathology and Experimental Neurology. 47: 19-28. PMID 3119782 DOI: 10.1097/00005072-198801000-00003  0.319
1988 Sobel RA, Hafler DA, Castro EE, Morimoto C, Weiner HL. Immunohistochemical analysis of suppressor-inducer and helper-inducer T cells in multiple sclerosis brain tissue. Annals of the New York Academy of Sciences. 540: 306-8. PMID 2905121 DOI: 10.1016/0165-5728(87)90382-1  0.36
1988 Schluesener HJ, Sobel RA, Weiner HL. Demyelinating experimental allergic encephalomyelitis (EAE) in the rat: treatment with a monoclonal antibody against activated T cells. Journal of Neuroimmunology. 18: 341-51. PMID 2454946 DOI: 10.1016/0165-5728(88)90055-0  0.361
1987 Sobel RA, Natale JM, Schneeberger EE. The immunopathology of acute experimental allergic encephalomyelitis. IV. An ultrastructural immunocytochemical study of class II major histocompatibility complex molecule (Ia) expression. Journal of Neuropathology and Experimental Neurology. 46: 239-49. PMID 3549982 DOI: 10.1097/00005072-198705000-00001  0.376
1987 Scott CF, Lambert JM, Goldmacher VS, Blatter WA, Sobel R, Schlossman SF, Benacerraf B. The pharmacokinetics and toxicity of murine monoclonal antibodies and of gelonin conjugates of these antibodies. International Journal of Immunopharmacology. 9: 211-25. PMID 3495503 DOI: 10.1016/0192-0561(87)90096-8  0.322
1987 McKee AC, Lewandrowski KB, Sobel RA. THE NEUROPATHOLOGY OF THE SMITH-LEMLI-OPITZ SYNDROME–CASE REPORT Journal of Neuropathology and Experimental Neurology. 46: 386. DOI: 10.1097/00005072-198705000-00169  0.369
1987 Tuohy V, Sobel R, Lees M. EAE induced by myelin proteolipid apoprotein (PLP) in various strains of mice Journal of Neuroimmunology. 16: 174. DOI: 10.1016/0165-5728(87)90400-0  0.31
1986 Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Annals of Neurology. 20: 362-4. PMID 3639720 DOI: 10.1002/Ana.410200316  0.303
1986 Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel RA. Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Annals of Neurology. 20: 289-95. PMID 3532930 DOI: 10.1002/Ana.410200304  0.309
1986 van der Veen RC, Sobel RA, Lees MB. Chronic experimental allergic encephalomyelitis and antibody responses in rabbits immunized with bovine proteolipid apoprotein. Journal of Neuroimmunology. 11: 321-33. PMID 2423554 DOI: 10.1016/0165-5728(86)90085-8  0.323
1984 Sobel RA, Blanchette BW, Colvin RB. 97 CHRONIC EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (cEAE) FOLLOWS ANTI-T CELL MONOCLONAL ANTIBODY MODULATION OF ACUTE F.AE (aEAE) IN ADULT GUINEA PIGS (GP) Journal of Neuropathology and Experimental Neurology. 43: 325. DOI: 10.1097/00005072-198405000-00106  0.302
Low-probability matches (unlikely to be authored by this person)
2017 Cruz-Herranz A, Sagan SA, Sobel RA, Green AJ, Zamvil SS. T cells targeting neuromyelitis optica autoantigen aquaporin-4 cause paralysis and visual system injury. Journal of Nature and Science. 3. PMID 28748216  0.3
1997 Waldner H, Sobel RA, Howard E, Kuchroo VK. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 159: 3100-3. PMID 9317104  0.3
1994 Sobel RA, Greer JM, Isaac J, Fondren G, Lees MB. Immunolocalization of proteolipid protein peptide 103-116 in myelin. Journal of Neuroscience Research. 37: 36-43. PMID 7511704 DOI: 10.1002/Jnr.490370106  0.3
2010 Saleh MA, Ishii K, Kim Y, Murakami A, Amagai M, Shibaguchi H, Tsuru H, Kuroki M, Murata A, Okuyama K, Sawada A, Egawa Y, Sakano S, Yagita H, Zúñiga-Pflücker JC, ... ... Sobel RA, et al. Cell adhesion in immunity (WS-103) Chairpersons: Tatsuo Kinashi, Sirpa Jalkanen International Immunology. 22. DOI: 10.1093/Intimm/Dxq365  0.299
2009 Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho I, Khoury S, Oukka M, Kuchroo VK. Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cells Nature Immunology. 10: 551-551. DOI: 10.1038/Ni0509-551B  0.299
2009 Crespo O, Kang S, Daneman R, Sobel R, Ho P, Steinman L, Robinson W. T.77. Tyrosine Kinases in Autoimmune Demyelination Clinical Immunology. 131: S73. DOI: 10.1016/J.Clim.2009.03.212  0.297
1992 Sobel RA, Kuchroo VK. The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions. Journal of Immunology (Baltimore, Md. : 1950). 149: 1444-51. PMID 1380045  0.297
2006 Platten M, Youssef S, Hur EM, Ho P, Ousman S, Sobel R, Steinman L. Sa.12. Blocking Angiotensin II Suppresses IL-12 Signaling in Autoreactive Th Cells and Treats Autoimmune Neuroinflammation Clinical Immunology. 119: S109. DOI: 10.1016/J.Clim.2006.04.244  0.297
2008 Sobel RA. A novel unifying hypothesis of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 67: 1032-4. PMID 18978540 DOI: 10.1097/Nen.0B13E31818Becal  0.295
2006 Capilla J, Maffei CM, Clemons KV, Sobel RA, Stevens DA. Experimental systemic infection with Cryptococcus neoformans var. grubii and Cryptococcus gattii in normal and immunodeficient mice. Medical Mycology. 44: 601-10. PMID 17071553 DOI: 10.1080/13693780600810040  0.293
2000 Clemons KV, Sobel RA, Stevens DA. Toxicity of LY303366, an echinocandin antifungal, in mice pretreated with glucocorticoids. Antimicrobial Agents and Chemotherapy. 44: 378-81. PMID 10639365 DOI: 10.1128/Aac.44.2.378-381.2000  0.293
2023 Schnell A, Huang L, Regan BML, Singh V, Vonficht D, Bollhagen A, Wang M, Hou Y, Bod L, Sobel RA, Chihara N, Madi A, Anderson AC, Regev A, Kuchroo VK. Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation. Nature Immunology. 24: 1908-1920. PMID 37828379 DOI: 10.1038/s41590-023-01645-4  0.293
1984 Sobel RA, Ellis WG, Nielsen SL, Davis RL. Central nervous system coccidioidomycosis: a clinicopathologic study of treatment with and without amphotericin B. Human Pathology. 15: 980-95. PMID 6479976 DOI: 10.1016/S0046-8177(84)80128-8  0.292
2003 Chiller TM, Sobel RA, Luque JC, Clemons KV, Stevens DA. Efficacy of amphotericin B or itraconazole in a murine model of central nervous system Aspergillus infection. Antimicrobial Agents and Chemotherapy. 47: 813-5. PMID 12543700 DOI: 10.1128/Aac.47.2.813-815.2003  0.29
2009 Awasthi A, Dardalhon V, Galileos G, Gao W, Strom T, Sobel R, Ho IC, Oukka M, Kuchroo V. OR.57. IL-4 Inhibits TGF-β-induced Foxp3+T Cells and, Together with TGF-β, Generates IL-9+IL-10+Foxp3-Effector T Cells Clinical Immunology. 131: S25. DOI: 10.1016/J.Clim.2009.03.069  0.29
1994 Chen M, Maeda A, Sobel R. Laminin (Ln) and endothelial cell (EC) integrin Ln receptors in multiple sclerosis (MS) lesions Journal of Neuroimmunology. 54: 198. DOI: 10.1016/0165-5728(94)90537-1  0.287
2002 Clemons KV, Sobel RA, Williams PL, Pappagianis D, Stevens DA. Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits. Antimicrobial Agents and Chemotherapy. 46: 2420-6. PMID 12121913 DOI: 10.1128/Aac.46.8.2420-2426.2002  0.287
1989 Sangruchi T, Sobel RA. Microglial and neural differentiation in human teratomas. Acta Neuropathologica. 78: 258-63. PMID 2763798 DOI: 10.1007/Bf00687755  0.286
2007 Sobel RA, Jaju P, Eaton MJ, Hinojoza JR. Monoclonal antibodies (mAbs) to myelin proteolipid protein (PLP) epitopes recognize neurons in the developing human CNS: 120.1 Journal of Neuropathology and Experimental Neurology. 66: 431. DOI: 10.1097/01.Jnen.0000268855.44172.F7  0.284
2007 Sobel RA, Jaju P, Eaton MJ, Hinojoza JR. Monoclonal antibodies (mAbs) to myelin proteolipid protein (PLP) epitopes recognize neurons in the developing human CNS Journal of Neuropathology and Experimental Neurology. 66: 431. DOI: 10.1096/Fasebj.21.5.A64-D  0.284
2005 Sobel RA. Ephrin A receptors and ligands in lesions and normal-appearing white matter in multiple sclerosis. Brain Pathology (Zurich, Switzerland). 15: 35-45. PMID 15779235 DOI: 10.1111/J.1750-3639.2005.Tb00098.X  0.284
1996 Maeda A, Sobel RA. Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 55: 300-9. PMID 8786388 DOI: 10.1097/00005072-199603000-00005  0.284
2019 Solomon DA, Geng H, Sobel RA, Subbaraj L, Tsang M, Rubenstein JL. Potential Genetic and Immunologic Mechanisms of Therapeutic Resistance and Disease Progression in CNS Lymphoma Elucidated Via Whole Brain Autopsy Studies Blood. 134: 1494-1494. DOI: 10.1182/Blood-2019-131302  0.284
2020 Sungnak W, Wagner A, Kowalczyk MS, Bod L, Kye YC, Sage PT, Sharpe AH, Sobel RA, Quintana FJ, Rozenblatt-Rosen O, Regev A, Wang C, Yosef N, Kuchroo VK. T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 33168576 DOI: 10.4049/jimmunol.2000748  0.283
2013 Kurnellas MP, Adams CM, Sobel RA, Steinman L, Rothbard JB. Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation. Science Translational Medicine. 5: 179ra42. PMID 23552370 DOI: 10.1126/Scitranslmed.3005681  0.283
2006 Zucker KE, Kamberi P, Sobel RA, Cloud G, Meli DN, Clemons KV, Stevens DA, Williams PL, Leib SL. Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis. Clinical and Experimental Immunology. 143: 458-66. PMID 16487245 DOI: 10.1111/J.1365-2249.2006.03011.X  0.283
2017 Clemons KV, Sobel RA, Martinez M, Correa-Oliveira R, Stevens DA. Lack of Efficacy of Liposomal Amphotericin B Against Acute and Chronic Trypanosoma cruzi Infection in Mice. The American Journal of Tropical Medicine and Hygiene. PMID 28820684 DOI: 10.4269/Ajtmh.16-0975  0.282
1998 Sobel RA, Hinojoza JR, Maeda A, Chen M. Endothelial cell integrin laminin receptor expression in multiple sclerosis lesions. The American Journal of Pathology. 153: 405-15. PMID 9708801 DOI: 10.1016/S0002-9440(10)65584-8  0.281
2006 Dunn S, Ousman S, Sobel R, Zuniga L, Baranzini S, Crowell A, Loh J, Oksenberg J, Steinman L. Sa.18. PPARα Mediates the Sexual Dimorphism in the Development of Th1-Mediated CNS Autoimmune Disease Clinical Immunology. 119: S111. DOI: 10.1016/J.Clim.2006.04.250  0.281
2009 Clemons KV, Capilla J, Sobel RA, Martinez M, Tong AJ, Stevens DA. Comparative efficacies of lipid-complexed amphotericin B and liposomal amphotericin B against coccidioidal meningitis in rabbits. Antimicrobial Agents and Chemotherapy. 53: 1858-62. PMID 19273680 DOI: 10.1128/Aac.01538-08  0.28
2008 Dardalhon V, Anderson A, Karman J, Chandwaskar R, Lee D, Cornejo M, Nishi N, Yamauchi A, Sobel R, Hirashima M, Kuchroo V. OR.26. Tim-3:Galectin-9 Pathway Expands Myeloid Suppressor Cells Clinical Immunology. 127: S12. DOI: 10.1016/J.Clim.2008.03.031  0.28
2012 Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB. Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. The Journal of Biological Chemistry. 287: 36423-34. PMID 22955287 DOI: 10.1074/Jbc.M112.371229  0.28
1993 Kuchroo VK, Martin CA, Greer JM, Ju ST, Sobel RA, Dorf ME. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 151: 4371-82. PMID 7691946  0.279
1996 Sobel RA, Zhang W, Wiederrecht G, Liu JS, Lu Y, Seidman CE, Nakanishi N, Seidman JG. CLINICOPATHOLOGIC CORRELATIONS IN CALCINEURIN Aα-DEFICIENT MICE Journal of Neuropathology and Experimental Neurology. 55: 620. DOI: 10.1097/00005072-199605000-00072  0.278
2008 Liao YJ, Safa P, Chen YR, Sobel RA, Boyden ES, Tsien RW. Anti-Ca2+ channel antibody attenuates Ca2+ currents and mimics cerebellar ataxia in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 2705-10. PMID 18272482 DOI: 10.1073/Pnas.0710771105  0.278
1998 Williams PL, Sobel RA, Sorensen KN, Clemons KV, Shuer LM, Royaltey SS, Yao Y, Pappagianis D, Lutz JE, Reed C, River ME, Lee BC, Bhatti SU, Stevens DA. A model of coccidioidal meningoencephalitis and cerebrospinal vasculitis in the rabbit. The Journal of Infectious Diseases. 178: 1217-21. PMID 9806065 DOI: 10.1086/515689  0.277
2000 Sorensen KN, Sobel RA, Clemons KV, Pappagianis D, Stevens DA, Williams PL. Comparison of fluconazole and itraconazole in a rabbit model of coccidioidal meningitis. Antimicrobial Agents and Chemotherapy. 44: 1512-7. PMID 10817701 DOI: 10.1128/Aac.44.6.1512-1517.2000  0.274
1993 Sobel RA, Greer JM, Isaac J, Fondren G, Lees MB. IMMUNOLOCALIZATION OF PROTEOLIPED PROTEIN (PLP) PEPTIDE 103–116 IN OLIGODENDROCYTES AND MYELIN Journal of Neuropathology and Experimental Neurology. 52: 287. DOI: 10.1097/00005072-199305000-00109  0.273
2007 Ousman S, Tomooka B, Van Noort J, O'Conner K, Wawrousek E, Hafler D, Sobel R, Robinson W, Steinman L. Protective and Therapeutic Role for α B-Crystallin in Autoimmune Demyelination Clinical Immunology. 123: S139. DOI: 10.1016/J.Clim.2007.03.034  0.272
2007 Capilla J, Clemons KV, Sobel RA, Stevens DA. Efficacy of amphotericin B lipid complex in a rabbit model of coccidioidal meningitis. The Journal of Antimicrobial Chemotherapy. 60: 673-6. PMID 17646202 DOI: 10.1093/Jac/Dkm264  0.271
1982 Ellis WG, Sobel RA, Nielsen SL. Leukoencephalopathy in patients treated with amphotericin B methyl ester. The Journal of Infectious Diseases. 146: 125-37. PMID 7108268 DOI: 10.1093/Infdis/146.2.125  0.269
1990 Lee JK, Choi B, Sobel RA, Chiocca EA, Martuza RL. Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. Journal of Neurosurgery. 73: 429-35. PMID 1696626 DOI: 10.3171/Jns.1990.73.3.0429  0.269
2016 Sati P, Oh J, Constable RT, Evangelou N, Guttmann CR, Henry RG, Klawiter EC, Mainero C, Massacesi L, McFarland H, Nelson F, Ontaneda D, Rauscher A, Rooney WD, Samaraweera AP, ... ... Sobel RA, et al. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nature Reviews. Neurology. PMID 27834394 DOI: 10.1038/Nrneurol.2016.166  0.268
1989 Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. Journal of Immunology (Baltimore, Md. : 1950). 142: 1523-7. PMID 2465343  0.268
2007 Kamberi P, Sobel RA, Clemons KV, Waldvogel A, Striebel JM, Williams PL, Stevens DA. Comparison of itraconazole and fluconazole treatments in a murine model of coccidioidal meningitis. Antimicrobial Agents and Chemotherapy. 51: 998-1003. PMID 17178793 DOI: 10.1128/Aac.00332-06  0.263
2008 Qi X, Inagaki K, Sobel RA, Mochly-Rosen D. Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats. The Journal of Clinical Investigation. 118: 173-82. PMID 18097471 DOI: 10.1172/Jci32636  0.263
2000 Sorensen KN, Sobel RA, Clemons KV, Calderon L, Howell KJ, Irani PR, Pappagianis D, Williams PL, Stevens DA. Comparative efficacies of terbinafine and fluconazole in treatment of experimental coccidioidal meningitis in a rabbit model. Antimicrobial Agents and Chemotherapy. 44: 3087-91. PMID 11036027 DOI: 10.1128/Aac.44.11.3087-3091.2000  0.261
2001 Ringer TM, Neumann-Haefelin T, Sobel RA, Moseley ME, Yenari MA. Reversal of early diffusion-weighted magnetic resonance imaging abnormalities does not necessarily reflect tissue salvage in experimental cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 32: 2362-9. PMID 11588327 DOI: 10.1161/Hs1001.096058  0.261
2018 Sage PT, Schildberg FA, Sobel RA, Kuchroo VK, Freeman GJ, Sharpe AH. Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 29531164 DOI: 10.4049/Jimmunol.1701231  0.261
2023 Gupta S, Simic M, Sagan SA, Shepherd C, Duecker J, Sobel RA, Dandekar R, Wu GF, Wu W, Pak JE, Hauser SL, Lim W, Wilson MR, Zamvil SS. CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity. Neurology(R) Neuroimmunology & Neuroinflammation. 10. PMID 36657993 DOI: 10.1212/NXI.0000000000200080  0.261
2007 Sobel RA. Neuropathology--for the living and the future. Journal of Neuropathology and Experimental Neurology. 66: 1057-8. PMID 18090914 DOI: 10.1097/Nen.0B013E31815D8C10  0.261
1981 Sobel RA, DeArmond SJ, Forno LS, Eng LF. Glial fibrillary acidic protein in hepatic encephalopathy. An immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 40: 625-32. PMID 7028923 DOI: 10.1097/00005072-198111000-00004  0.258
2022 Sobel RA, Albertelli M, Hinojoza JR, Eaton MJ, Grimes KV, Rubenstein E. Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis. Journal of Neuropathology and Experimental Neurology. PMID 35521963 DOI: 10.1093/jnen/nlac028  0.256
2012 Zerboni L, Sobel RA, Lai M, Triglia R, Steain M, Abendroth A, Arvin A. Apparent expression of varicella-zoster virus proteins in latency resulting from reactivity of murine and rabbit antibodies with human blood group a determinants in sensory neurons. Journal of Virology. 86: 578-83. PMID 22013055 DOI: 10.1128/Jvi.05950-11  0.256
2014 Bruinsma I, Eijsink V, Kooi EJ, Baranzini S, Ji XH, Axtell R, Han M, Kuipers H, Sobel R, Polman C, Geurts J, Martens GJM, Poelmans G, Steinman L, Jong BD. Genome-wide RNA expression profiling in human grey and white matter tissue reveals a role for PSA-NCAM dysregulation in MS pathogenesis Journal of Neuroimmunology. 275: 180-181. DOI: 10.1016/J.Jneuroim.2014.08.485  0.255
2007 Qin Y, Sobel RA. Mechanisms of injury in multiple sclerosis: involvement of antineuroaxonal humoral autoimmunity. Expert Review of Clinical Immunology. 3: 653-7. PMID 20477013 DOI: 10.1586/1744666X.3.5.653  0.255
1992 Lee JK, Sobel RA, Chiocca EA, Kim TS, Martuza RL. Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. Journal of Neuro-Oncology. 14: 101-12. PMID 1432035 DOI: 10.1007/Bf00177613  0.254
2019 Singh AB, Kan CFK, Kraemer FB, Sobel RA, Liu J. Liver-specific knockdown of long-chain acyl-CoA synthetase 4 reveals its key role in VLDL-TG metabolism and phospholipid synthesis in mice fed a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. PMID 30721098 DOI: 10.1152/Ajpendo.00503.2018  0.253
2010 Zerboni L, Sobel RA, Ramachandran V, Rajamani J, Ruyechan W, Abendroth A, Arvin A. Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia. Journal of Virology. 84: 3421-30. PMID 20106930 DOI: 10.1128/Jvi.02416-09  0.253
2007 Graham KL, Zuniga LA, Zabel BA, Butcher EC, Sobel RA. Chemokine-like Receptor-1 (CMKLR1) Regulates Experimental Autoimmune Encephalomyelitis Clinical Immunology. 123: S138. DOI: 10.1016/J.Clim.2007.03.031  0.25
2003 Han HS, Karabiyikoglu M, Kelly S, Sobel RA, Yenari MA. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 589-98. PMID 12771574 DOI: 10.1097/01.Wcb.0000059566.39780.8D  0.249
2001 Zhang Z, Sobel RA, Cheng D, Steinberg GK, Yenari MA. Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia. Brain Research. Molecular Brain Research. 95: 75-85. PMID 11687278 DOI: 10.1016/S0169-328X(01)00247-9  0.249
1983 Sobel RA, Blanchette BW, Colvin RB. 167 FIBRONECTIN (Fn) IN ACUTE EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAF.). AN IMMUNOHISTOCHEHICAL STUDY USING MONOCLONAL ANTIBODIES (Mab) Journal of Neuropathology and Experimental Neurology. 42: 360. DOI: 10.1097/00005072-198305000-00172  0.249
2019 Harrison W, Elsamadicy AA, McMahon JT, Chagoya G, Sobel RA, McLendon RE, Adamson C. Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas. Journal of Neuropathology and Experimental Neurology. PMID 31361005 DOI: 10.1093/Jnen/Nlz060  0.248
1995 Brenner T, Galperin M, Gallily R, Sicsic C, Sobel R, Szafer F, Brocke S, Steinman L. Involvement of nitric oxide in CNS demyelination and inflammation Journal of Neuroimmunology. 56: 12-12. DOI: 10.1016/0165-5728(95)98888-I  0.247
1986 Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Sobel RA. IMMUNOHISTOCHEMICAL IDENTIFICATION OF HTLV-III ANTIGEN IN BRAIN FROM PATIENTS WITH THE SUBACUTE ENCEPHALITIS (SE) OF THE ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) Journal of Neuropathology and Experimental Neurology. 45: 331. DOI: 10.1097/00005072-198605000-00055  0.247
2013 Hsu JL, Khan MA, Sobel RA, Jiang X, Clemons KV, Nguyen TT, Stevens DA, Martinez M, Nicolls MR. Aspergillus fumigatus invasion increases with progressive airway ischemia. Plos One. 8: e77136. PMID 24155924 DOI: 10.1371/Journal.Pone.0077136  0.246
1996 Encinas JA, Lees MB, Sobel RA, Symonowicz C, Greer JM, Shovlin CL, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. Journal of Immunology (Baltimore, Md. : 1950). 157: 2186-92. PMID 8757345  0.245
2003 Yenari MA, Zhao H, Giffard RG, Sobel RA, Sapolsky RM, Steinberg GK. Gene therapy and hypothermia for stroke treatment. Annals of the New York Academy of Sciences. 993: 54-68; discussion 79. PMID 12853295 DOI: 10.1111/J.1749-6632.2003.Tb07511.X  0.245
1991 Halliday AL, Sobel RA, Martuza RL. Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2. Journal of Neurosurgery. 74: 248-53. PMID 1846409 DOI: 10.3171/Jns.1991.74.2.0248  0.244
1992 Greer JM, Kuchroo VK, Sobel RA, Lees MB. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. Journal of Immunology (Baltimore, Md. : 1950). 149: 783-8. PMID 1378866  0.244
1987 Sobel RA, Hanzakos JL, Blanchette BW, Williams AM, Dellapelle P, Colvin RB. Anti-T cell monoclonal antibodies in vivo. I. Inhibition of delayed hypersensitivity but not cutaneous basophil hypersensitivity reactions. Journal of Immunology (Baltimore, Md. : 1950). 138: 2500-6. PMID 3494071  0.243
2007 Han MH, Hwang S, Roy D, Raine C, Robinson WH, Sobel RA, Han D, Steinman L. Proteomic Profiling of Multiple Sclerosis Lesions Identify Potential Targets for Therapy Clinical Immunology. 123: S153. DOI: 10.1016/J.Clim.2007.03.075  0.243
1988 Sobel RA, Hafler DA, Castro EE, Morimoto C, Weiner HL. The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions. Journal of Immunology (Baltimore, Md. : 1950). 140: 2210-4. PMID 2965183  0.241
1988 Tuohy VK, Sobel RA, Lees MB. Susceptibility to PLP-induced EAE is regulated by non-H-2 genes. Annals of the New York Academy of Sciences. 540: 709-11. PMID 2462841 DOI: 10.1111/J.1749-6632.1988.Tb27221.X  0.237
1983 Hess JR, Michaud J, Sobel RA, Herman MM, Rubinstein LJ. The kinetics of human glioblastomas maintained in an organ culture system. An in vitro autoradiographic study. Acta Neuropathologica. 61: 1-9. PMID 6624382 DOI: 10.1007/Bf00688379  0.237
1989 Medhkour A, Van Roey M, Sobel RA, Fingert HJ, Lee J, Martuza RL. Implantation of human meningiomas into the subrenal capsule of the nude mouse. A model for studies of tumor growth. Journal of Neurosurgery. 71: 545-50. PMID 2477514 DOI: 10.3171/Jns.1989.71.4.0545  0.236
1980 Sobel RA, Ellis WG, Nielsen SL. 158 AMPHOTERICIN B METHYL ESTER EFFECTS OH HUMAN CENTRAL NERVOUS SYSTEM Journal of Neuropathology and Experimental Neurology. 39: 389. DOI: 10.1097/00005072-198005000-00165  0.234
1993 Sobel RA. Vestibular (acoustic) schwannomas: histologic features in neurofibromatosis 2 and in unilateral cases. Journal of Neuropathology and Experimental Neurology. 52: 106-13. PMID 8440992 DOI: 10.1097/00005072-199303000-00002  0.234
2022 Tang R, Acharya N, Subramanian A, Purohit V, Tabaka M, Hou Y, He D, Dixon KO, Lambden C, Xia J, Rozenblatt-Rosen O, Sobel RA, Wang C, Regev A, Anderson AC, et al. Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function. Science Immunology. 7: eabm0631. PMID 35275752 DOI: 10.1126/sciimmunol.abm0631  0.233
1987 Schluesener HJ, Sobel RA, Linington C, Weiner HL. A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 139: 4016-21. PMID 3500978  0.233
2002 Williams PL, Leib SL, Kamberi P, Leppert D, Sobel RA, Bifrare YD, Clemons KV, Stevens DA. Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis. The Journal of Infectious Diseases. 186: 1692-5. PMID 12447750 DOI: 10.1086/345365  0.23
1990 Sobel RA, Mitchell ME, Fondren G. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. The American Journal of Pathology. 136: 1309-16. PMID 1972610  0.229
1985 Sobel RA, Michaud J. Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma. Acta Neuropathologica. 68: 256-8. PMID 4082928 DOI: 10.1007/Bf00690204  0.229
2003 Kaufman DL, Heinrich BS, Willett C, Perry A, Finseth F, Sobel RA, MacCollin M. Somatic instability of the NF2 gene in schwannomatosis. Archives of Neurology. 60: 1317-20. PMID 12975302 DOI: 10.1001/Archneur.60.9.1317  0.229
2001 Clemons KV, Sobel RA, Williams PL, Stevens DA. Comparative toxicities and pharmacokinetics of intrathecal lipid (amphotericin B colloidal dispersion) and conventional deoxycholate formulations of amphotericin B in rabbits. Antimicrobial Agents and Chemotherapy. 45: 612-5. PMID 11158765 DOI: 10.1128/Aac.45.2.612-615.2001  0.228
1981 Corkill G, Hanson FW, Sobel RA, Keller TM. Apoplexy in a prolactin microadenoma leading to remission of galactorrhea and amenorrhea. Surgical Neurology. 15: 114-5. PMID 7195610 DOI: 10.1016/0090-3019(81)90025-2  0.227
1994 Greer JM, Sobel RA, Sette A, Lees MB, Kuchroo VK. Autoantigenic PLP peptides identified by MHC binding Journal of Neuroimmunology. 54: 165. DOI: 10.1016/0165-5728(94)90341-7  0.226
1991 Sobel RA. Adhesion molecules (AM) in CNS immunopathology Journal of Neuroimmunology. 35: 5. DOI: 10.1016/0165-5728(91)90838-X  0.226
1979 Sobel RA, Ruebner BH. Buerger's disease involving the celiac artery. Human Pathology. 10: 112-5. PMID 428990 DOI: 10.1016/S0046-8177(79)80080-5  0.226
1999 Sobel RA, Elahi AW, Smith-Norowitz T, Mokhtarian F. PATHOGENESIS OF CNS WHITE MATTER (WM) INJURY IN SEMLIKI FOREST VIRUS (SFV) ENCEPHALITIS Journal of Neuropathology and Experimental Neurology. 58: 526. DOI: 10.1097/00005072-199905000-00078  0.225
2006 Araki M, Chung D, Vijaykrishnan L, Sobel R, Hunter K, Peterson L, Wicker L, Kuchroo V. OR.21. Idd5.4 On Chromosome 1 Mediates Resistance to Experimental Autoimmune Encephalomyelitis Clinical Immunology. 119: S11-S12. DOI: 10.1016/J.Clim.2006.04.023  0.224
2011 Qi X, Disatnik MH, Shen N, Sobel RA, Mochly-Rosen D. Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo. Molecular Biology of the Cell. 22: 256-65. PMID 21119009 DOI: 10.1091/Mbc.E10-06-0551  0.222
1999 Zhuo M, Zhang W, Son H, Mansuy I, Sobel RA, Seidman J, Kandel ER. A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 96: 4650-5. PMID 10200317 DOI: 10.1073/Pnas.96.8.4650  0.222
1990 Halliday AL, Sobel RA, Martuza RL. BENIGN INTRASPINAL NERVE SHEATH TUMORS (SNST) Journal of Neuropathology and Experimental Neurology. 49: 320. DOI: 10.1097/00005072-199005000-00182  0.222
1999 Encinas JA, Wicker LS, Peterson LB, Mukasa A, Teuscher C, Sobel R, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2. Nature Genetics. 21: 158-60. PMID 9988264 DOI: 10.1038/5941  0.221
2018 Hsu JL, Manouvakhova OV, Clemons KV, Inayathullah M, Tu AB, Sobel RA, Tian A, Nazik H, Pothineni VR, Pasupneti S, Jiang X, Dhillon GS, Bedi H, Rajadas J, Haas H, et al. Microhemorrhage-associated tissue iron enhances the risk forinvasion in a mouse model of airway transplantation. Science Translational Medicine. 10. PMID 29467298 DOI: 10.1126/Scitranslmed.Aag2616  0.219
2014 Hsu JL, Jiang X, Khan MA, Sobel RA, Clemons KV, Stevens DA, Nicolls MR. AspergillusInvasion Increases with Progressive Airway Ischemia Annals of the American Thoracic Society. 11: S79-S79. DOI: 10.1513/Annalsats.201307-240Mg  0.219
2018 Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Correction: Peroxisome proliferator-activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. The Journal of Experimental Medicine. PMID 29773642 DOI: 10.1084/jem.2006183905142018c  0.217
1981 Sobel RA, Trice JE, Nielsen SL, Ellis WG. Pineoblastoma with ganglionic and glial differentiation: report of two cases. Acta Neuropathologica. 55: 243-6. PMID 7349581 DOI: 10.1007/Bf00691324  0.216
1990 Sobel RA. Book Review Essential Pathology Edited by Emanuel Rubin and John L. Farber. 850 pp., illustrated. Philadelphia, J.B. Lippincott, 1990. $42.95. New England Journal of Medicine. 323: 1429-1429. DOI: 10.1056/Nejm199011153232022  0.216
1991 Sobel RA. Book Review Textbook of Fetal and Perinatal Pathology Edited by Jonathan S. Wigglesworth and Don B. Singer. 1308 pp. in two volumes, illustrated. Boston, Blackwell Scientific, 1991. $250. (Distributed by Mosby—Year Book, St. Louis.) New England Journal of Medicine. 325: 437-438. DOI: 10.1056/Nejm199108083250624  0.215
1996 Greer JM, Sobel RA, Sette A, Southwood S, Lees MB, Kuchroo VK. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. Journal of Immunology (Baltimore, Md. : 1950). 156: 371-9. PMID 8598487  0.214
1987 Gabuzda DH, Sobel RA. HIV antigen in brains of patients with AIDS. Annals of Neurology. 22: 668. PMID 3480698 DOI: 10.1002/Ana.410220526  0.214
2012 Sternberg Z, Cesario A, Rittenhouse-Olson K, Sobel RA, Leung YK, Pankewycz O, Zhu B, Whitcomb T, Sternberg DS, Munschauer FE. Acamprosate modulates experimental autoimmune encephalomyelitis. Inflammopharmacology. 20: 39-48. PMID 22090150 DOI: 10.1007/s10787-011-0097-1  0.213
2015 Herrick MK, Sobel RA. Lysia K.S. Forno, MD February 14, 1918-May 8, 2015. Journal of Neuropathology and Experimental Neurology. 74: 1180-2. PMID 26904767 DOI: 10.1093/Jnen/74.12.1180  0.213
1990 Hagler DA, Sobel RA. Case records of the Massachusetts General Hospital. A previously healthy 41-year-old man with meningoencephalitis and the rapid development of coma New England Journal of Medicine. 323: 1123-1135. PMID 2215581 DOI: 10.1056/Nejm199010183231608  0.208
1986 de la Monte SM, Bour C, Sobel RA, Radhakrishnan VV, Jupiter JB, Smith RJ, Hedley-Whyte ET. INFLUENCE OF REJECTION AND VASCULARIZATION ON REGENERATION OF NERVE GRAFTS (NG) IN RABBITS Journal of Neuropathology and Experimental Neurology. 45: 354. DOI: 10.1097/00005072-198605000-00119  0.206
2015 Sobel RA. Greenfield's Neuropathology, Ninth Edition: 2-Volume Set Journal of Neuropathology & Experimental Neurology. 74: 1185-1185. DOI: 10.1093/Jnen/74.12.1185  0.205
1983 Sobel RA, Nielsen SL, Hoeprich PD. Toxic effects of amphotericin B methyl ester Journal of Infectious Diseases. 147: 781-785. PMID 6842015 DOI: 10.1093/Infdis/147.4.784A  0.205
1997 Hevner R, Sobel RA. November 1996--premature baby with lethargy and coma. Brain Pathology (Zurich, Switzerland). 7: 839-40. PMID 9161734 DOI: 10.1111/J.1750-3639.1997.Tb01069.X  0.204
1987 Sobel RA, Blanchette BW, Russo MA, Williams AM, Colvin RB. Anti-T cell monoclonal antibodies in vivo. II. Modulation of acute and chronic experimental allergic encephalomyelitis (EAE) in guinea pigs. Journal of Immunology (Baltimore, Md. : 1950). 138: 2507-13. PMID 3494072  0.203
1988 Tuohy VK, Lu ZJ, Sobel RA, Laursen RA, Lees MB. A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 141: 1126-30. PMID 2456341  0.2
1994 Kuchroo VK, Greer JM, Kaul D, Ishioka G, Franco A, Sette A, Sobel RA, Lees MB. A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 153: 3326-36. PMID 7522258  0.199
1989 Sobel RA, Mitchell ME. Fibronectin in multiple sclerosis lesions. The American Journal of Pathology. 135: 161-8. PMID 2528301  0.197
1991 Sobel RA, Tuohy VK, Lees MB. Parental MHC molecule haplotype expression in (SJL/J x SWR)F1 mice with acute experimental allergic encephalomyelitis induced with two different synthetic peptides of myelin proteolipid protein. Journal of Immunology (Baltimore, Md. : 1950). 146: 543-9. PMID 1702806  0.197
1988 Sobel RA, Schneeberger EE, Colvin RB. The immunopathology of acute experimental allergic encephalomyelitis. V. A light microscopic and ultrastructural immunohistochemical analysis of fibronectin and fibrinogen. The American Journal of Pathology. 131: 547-58. PMID 2968050  0.196
2008 Araki M, Chung D, Vijayakrishnan L, Sobel R, Oukka M, Wicker L, Sharpe A, Kuchroo V. Sa.92. Ligand Independent CTLA-4 Can Replace Some but Not All the Functions of Full Length CTLA-4 Clinical Immunology. 127: S110-S111. DOI: 10.1016/J.Clim.2008.03.313  0.196
2007 Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity The Journal of Cell Biology. 176: i9-i9. DOI: 10.1083/JCB1764OIA9  0.191
1984 Sobel RA, Blanchette BW, Colvin RB. Pre-inflammatory expression of fibronectin (Fn) and Ia in acute experimental allergic encephalomyelitis (EAE): modulation of endothelial cells (EC) in the immune response detected by quantitative immunoperoxidase studies using monoclonal antibodies (MAb). Progress in Clinical and Biological Research. 146: 81-6. PMID 6201925  0.19
2021 Wagner A, Wang C, Fessler J, DeTomaso D, Avila-Pacheco J, Kaminski J, Zaghouani S, Christian E, Thakore P, Schellhaass B, Akama-Garren E, Pierce K, Singh V, Ron-Harel N, Douglas VP, ... ... Sobel RA, et al. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. PMID 34216539 DOI: 10.1016/j.cell.2021.05.045  0.19
2014 Graham KL, Zhang JV, Lewén S, Burke TM, Dang T, Zoudilova M, Sobel RA, Butcher EC, Zabel BA. Structure-activity relationship: charged ethyltrimethylamine critical for target potency. Plos One. DOI: 10.1371/Journal.Pone.0112925.T002  0.188
1997 Brenner T, Brocke S, Szafer F, Sobel RA, Parkinson JF, Perez DH, Steinman L. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 158: 2940-6. PMID 9058833  0.187
1992 Kuchroo VK, Sobel RA, Laning JC, Martin CA, Greenfield E, Dorf ME, Lees MB. Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. Journal of Immunology (Baltimore, Md. : 1950). 148: 3776-82. PMID 1376341  0.187
2001 Sobel RA. The extracellular matrix in multiple sclerosis: an update. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 34: 603-9. PMID 11323746  0.186
2017 Sobel RA. Editor's Note: Transitions at the JNEN. Journal of Neuropathology and Experimental Neurology. PMID 28419288 DOI: 10.1093/Jnen/Nlx019  0.183
2009 Ganjoo KN, Raman R, Sobel RA, Pinto HA. Opportunistic enteroviral meningoencephalitis: an unusual treatable complication of rituximab therapy. Leukemia & Lymphoma. 50: 673-5. PMID 19373672 DOI: 10.1080/10428190902782210  0.181
1981 Sobel RA, Woerner S. Rubinstein-Taybi syndrome and nasopharyngeal rhabdomyosarcoma. The Journal of Pediatrics. 99: 1000-1. PMID 7310576 DOI: 10.1016/S0022-3476(81)80043-1  0.181
1988 Tuohy VK, Sobel RA, Lees MB. Myelin proteolipid protein-induced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice. Journal of Immunology (Baltimore, Md. : 1950). 140: 1868-73. PMID 3257990  0.175
1993 Bell RB, Lindsey JW, Sobel RA, Hodgkinson S, Steinman L. Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 150: 4085-92. PMID 8473751  0.171
1984 Sobel RA, Blanchette BW, Bhan AK, Colvin RB. The immunopathology of experimental allergic encephalomyelitis. II. Endothelial cell Ia increases prior to inflammatory cell infiltration. Journal of Immunology (Baltimore, Md. : 1950). 132: 2402-7. PMID 6425402  0.17
1984 Sobel RA, Blanchette BW, Bhan AK, Colvin RB. The immunopathology of experimental allergic encephalomyelitis. I. Quantitative analysis of inflammatory cells in situ. Journal of Immunology (Baltimore, Md. : 1950). 132: 2393-401. PMID 6371137  0.164
2005 Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Correction Journal of Experimental Medicine. 202: 877-877. DOI: 10.1084/Jem.20050308082505C  0.162
1998 Sullivan TJ, Hurwitz AA, Sobel RA, Allison JP. Induction of CNS inflammatory disease as a consequence of CTLA-4/B7 blockade Faseb Journal. 12: A1092.  0.154
1997 Sobel RA, Hinoioza JR. ENDOTHELIAL CELL (EC) INTEGRES LAMINHM (Ln) RECEPTOR EXPRESSION IN MULTIPLE SCLEROSIS (MS) LESIONS-IMMUNOELECTRON MICROSCOPY (IEM) AND FUNCTIONAL CORRELATES Journal of Neuropathology and Experimental Neurology. 56: 579. DOI: 10.1097/00005072-199705000-00047  0.149
1991 Lees MB, Kuchroo VK, Sobel RA. Myelin proteolipid protein: Its role in experimental allergic encephalomyelitis International Pediatrics. 6: 84-90.  0.149
2022 Shen Q, Otoki Y, Sobel RA, Nagra RM, Taha AY. Evidence of increased sequestration of pro-resolving lipid mediators within brain esterified lipid pools of multiple sclerosis patients. Multiple Sclerosis and Related Disorders. 68: 104236. PMID 36308971 DOI: 10.1016/j.msard.2022.104236  0.128
1987 Sobel RA, Ames MB. MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) MOLECULE EXPRESSION IN THE HUMAN CENTRAL NERVOUS SYSTEM (CNS)–IMMUNOHISTOCHEMICAL ANALYSIS OF 40 CASES Journal of Neuropathology and Experimental Neurology. 46: 398. DOI: 10.1097/00005072-198705000-00207  0.125
2024 Sur M, Rasquinha MT, Mone K, Massilamany C, Lasrado N, Gurumurthy C, Sobel RA, Reddy J. Investigation into Cardiac Myhc-α 334-352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity. Cells. 13. PMID 38334626 DOI: 10.3390/cells13030234  0.12
1989 Sobel RA. FIBRONECTIN (FN) IN MULTIPLE SCLEROSIS (MS) LESIONS Journal of Neuropathology and Experimental Neurology. 48: 324. DOI: 10.1097/00005072-198905000-00075  0.117
1986 Sobel RA, van der Veen RC, Lees MB. The immunopathology of chronic experimental allergic encephalomyelitis induced in rabbits with bovine proteolipid protein. Journal of Immunology (Baltimore, Md. : 1950). 136: 157-63. PMID 2415615  0.114
1986 Sobel RA, Collins AB, Colvin RB, Bhan AK. The in situ cellular immune response in acute herpes simplex encephalitis. The American Journal of Pathology. 125: 332-8. PMID 3789090  0.113
2012 Sternberg Z, Cesario A, Rittenhouse-Olson K, Sobel RA, Leung Y, Pankewycz O, Zhu B, Whitcomb T, Sternberg DS, Munschauer FE. Erratum to: Acamprosate modulates experimental autoimmune encephalomyelitis Inflammopharmacology. 20: 49-49. DOI: 10.1007/s10787-012-0120-1  0.109
2022 Rasquinha MT, Lasrado N, Sur M, Mone K, Qiu H, Riethoven JJ, Sobel RA, Reddy J. A Monovalent Mt10-CVB3 Vaccine Prevents CVB4-Accelerated Type 1 Diabetes in NOD Mice. Vaccines. 11. PMID 36679922 DOI: 10.3390/vaccines11010076  0.108
1996 Smith ME, Sobel RA. Effect of cytokines on phagocytic functions in macrophages and microglia Faseb Journal. 10: A1423.  0.098
1985 Sobel RA, Colvin RB. The immunopathology of experimental allergic encephalomyelitis (EAE). III. Differential in situ expression of strain 13 Ia on endothelial and inflammatory cells of (strain 2 x strain 13)F1 guinea pigs with EAE. Journal of Immunology (Baltimore, Md. : 1950). 134: 2333-7. PMID 2579141  0.097
1987 Sobel RA. Book ReviewHuman Pathology: An introduction to the study of disease New England Journal of Medicine. 316: 490-490. DOI: 10.1056/NEJM198702193160826  0.094
2005 Clemons KV, Kamberi P, Chiller TM, Sobel RA, Brummer E, Kolls J, Stevens DA. Effects of interferon-gene therapy in the murine central nervous system and concentrations in cerebrospinal fluid after intrathecal or intracerebral administration Biotechnology. 4: 11-18.  0.084
1989 Brown RH, Sobel RA. A 60-year-old man with granulomatous interstitial nephritis followed by neurologic disease New England Journal of Medicine. 321: 739-750.  0.081
1994 Mokhtarian F, Maeda A, Chen M, Sobel R. TH1 cytokines in Semliki Forest Virus (SFV) encephalitis Journal of Neuroimmunology. 54: 198. DOI: 10.1016/0165-5728(94)90538-X  0.078
1991 Wen PY, Sobel RA. A 60-year-old man with multiple cerebral infarcts and cutaneous hemorrhagic lesions New England Journal of Medicine. 325: 714-726.  0.078
1989 Sobel RA. Book ReviewPathology: The mechanisms of disease New England Journal of Medicine. 321: 914-914. DOI: 10.1056/NEJM198909283211329  0.072
1991 Samuels MA, Sobel RA. A 35-year-old man with changed mental status and multiple intracerebral lesions New England Journal of Medicine. 325: 414-422.  0.065
1996 Shuster DL, Sobel RA, Ratner N. THE BLOOD-TUMOR BARRIER IN NEUROFIBROMA Journal of Neuropathology and Experimental Neurology. 55: 628. DOI: 10.1097/00005072-199605000-00103  0.063
1986 Sobel RA, Colvin RB. Responder strain-specific enhancement of endothelial and mononuclear cell Ia in delayed hypersensitivity reactions in (strain 2 X strain 13)F1 guinea pigs. Journal of Immunology (Baltimore, Md. : 1950). 137: 2132-8. PMID 3531327  0.061
1991 Leifer D, Sobel RA. A 71-year-old woman with a sensorimotor neuropathy and radiographically demonstrable abnormalities New England Journal of Medicine. 325: 1723-1735.  0.057
1988 Parker SW, Sobel RA. A 72-year-old man with headaches and multiple cranial-nerve palsies New England Journal of Medicine. 318: 760-768.  0.055
1988 Kowall NW, Sobel RA. A 27-year-old man with acute myelomonocytic leukemia in remission and repeated intracranial hemorrhages New England Journal of Medicine. 318: 427-440.  0.048
1981 Sobel RA, DeArmond SJ, Forno LS, Eng LF. 70 GLIAL FIBRILLARY ACIDIC PROTEIN IN HEPATIC ENCEPHALOPATHY Journal of Neuropathology and Experimental Neurology. 40: 322. DOI: 10.1097/00005072-198105000-00077  0.046
2001 Sobel RA. Matrix metalloproteinases and diffuse white matter injury Stroke. 32: 1167-1168.  0.044
1965 Spitzer SP, Sobel R. Selective Perception and Staff Consensus in the Viewing of Psychiatric Patients Journal of Counseling Psychology. 12: 100. DOI: 10.1037/h0020500  0.043
1992 Gruber ML, Sobel RA. A 45-year-old man with confusion, seizures, and few focal findings New England Journal of Medicine. 327: 107-116.  0.032
1968 Socolow EL, Dunlap D, Sobel RA, Ingbar SH. A correlative study of the effect of iodide administration in the rat on thyroidal iodide transport and organic iodine content. Endocrinology. 83: 737-43. PMID 5685963 DOI: 10.1210/endo-83-4-737  0.028
1998 Goldstein AO, Sobel RA, Martin JD, Crocker SD, Malek SH. How does North Carolina law enforcement limit youth access to tobacco products? A study of officers' attitudes and behaviors. North Carolina Medical Journal. 59: 90-4. PMID 9558895  0.021
1999 Goldstein AO, Sobel RA, Newman GR. Tobacco and alcohol use in G-rated children's animated films. Jama. 281: 1131-6. PMID 10188668 DOI: 10.1001/jama.281.12.1131  0.02
1998 Sobel RA, Goldstein AO, Ives TJ. Impact of smoking control rules on restaurants in Orange County, North Carolina. North Carolina Medical Journal. 59: 288. PMID 9785901  0.012
1998 Goldstein AO, Sobel RA. Environmental tobacco smoke regulations have not hurt restaurant sales in North Carolina. North Carolina Medical Journal. 59: 284-7. PMID 9785900  0.01
1985 Sobel RA. Book ReviewPathology of Skeletal Muscle New England Journal of Medicine. 312: 382-382. DOI: 10.1056/NEJM198502073120622  0.01
1969 Sheehan EF, Robb HE, Sobel R. From Left to Right The History Teacher. 2: 57. DOI: 10.2307/3054270  0.01
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