Anat O. Stemmer-Rachamimov, MD, University of Milan - Publications

Pathology Masssachusetts General Hospital, Boston, MA, United States 
Heredetary Brain Tumor Syndrome, NeuropathologyOphthalmic Pathology, Surgicals

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, ... ... Stemmer-Rachamimov AO, et al. DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome. Acta Neuropathologica. PMID 30123936 DOI: 10.1007/s00401-018-1899-7  0.32
2018 Wu LMN, Deng Y, Wang J, Zhao C, Wang J, Rao R, Xu L, Zhou W, Choi K, Rizvi TA, Remke M, Rubin JB, Johnson RL, Carroll TJ, Stemmer-Rachamimov AO, et al. Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell. 33: 292-308.e7. PMID 29438698 DOI: 10.1016/j.ccell.2018.01.005  0.36
2017 Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA. Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas. Journal of Neurosurgery. 1-10. PMID 28621619 DOI: 10.3171/2016.11.JNS16913  0.36
2016 Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, ... Stemmer-Rachamimov AO, et al. Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell. 29: 669-83. PMID 27165742 DOI: 10.1016/j.ccell.2016.03.027  0.36
2015 Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M. Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade. Neuro-Oncology. PMID 26597949 DOI: 10.1093/neuonc/nov285  0.36
2015 Gao X, Zhao Y, Stemmer-Rachamimov AO, Liu H, Huang P, Chin S, Selig MK, Plotkin SR, Jain RK, Xu L. Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model. Proceedings of the National Academy of Sciences of the United States of America. PMID 26554010 DOI: 10.1073/pnas.1512570112  0.36
2015 Marciscano AE, Stemmer-Rachamimov AO, Niemierko A, Larvie M, Curry WT, Barker FG, Martuza RL, McGuone D, Oh KS, Loeffler JS, Shih HA. Benign meningiomas (WHO Grade I) with atypical histological features: correlation of histopathological features with clinical outcomes. Journal of Neurosurgery. 1-9. PMID 26274991 DOI: 10.3171/2015.1.JNS142228  0.36
2015 Kim LA, Wong LL, Amarnani DS, Bigger-Allen AA, Hu Y, Marko CK, Eliott D, Shah VA, McGuone D, Stemmer-Rachamimov AO, Gai X, D'Amore PA, Arboleda-Velasquez JF. Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Molecular Vision. 21: 673-87. PMID 26120272  1
2015 Stivaros SM, Stemmer-Rachamimov AO, Alston R, Plotkin SR, Nadol JB, Quesnel A, O'Malley J, Whitfield GA, McCabe MG, Freeman SR, Lloyd SK, Wright NB, Kilday JP, Kamaly-Asl ID, Mills SJ, et al. Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2. Journal of Medical Genetics. PMID 26104281 DOI: 10.1136/jmedgenet-2015-103050  1
2015 Prabhakar S, Zhang X, Goto J, Han S, Lai C, Bronson R, Sena-Esteves M, Ramesh V, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO. Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model. Neurobiology of Disease. 82: 22-31. PMID 26019056 DOI: 10.1016/j.nbd.2015.04.018  1
2015 Redjal N, Agarwalla PK, Dietrich J, Dinevski N, Stemmer-Rachamimov A, Nahed BV, Loeffler JS. Remote acute demyelination after focal proton radiation therapy for optic nerve meningioma Journal of Clinical Neuroscience. 22: 1367-1369. PMID 25937571 DOI: 10.1016/j.jocn.2015.02.017  1
2015 Shapiro KA, McGuone D, Deshpande V, Sadow PM, Stemmer-Rachamimov A, Staley KJ. Failure to detect human papillomavirus in focal cortical dysplasia type IIb. Annals of Neurology. 78: 63-7. PMID 25893423 DOI: 10.1002/ana.24422  1
2015 Taylor JW, Dietrich J, Gerstner ER, Norden AD, Rinne ML, Cahill DP, Stemmer-Rachamimov A, Wen PY, Betensky RA, Giorgio DH, Snodgrass K, Randall AE, Batchelor TT, Chi AS. Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma. Journal of Neuro-Oncology. 121: 557-63. PMID 25411098 DOI: 10.1007/s11060-014-1667-z  1
2015 Gehlhausen JR, Park SJ, Hickox AE, Shew M, Staser K, Rhodes SD, Menon K, Lajiness JD, Mwanthi M, Yang X, Yuan J, Territo P, Hutchins G, Nalepa G, Yang FC, ... ... Stemmer-Rachamimov A, et al. A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation. Human Molecular Genetics. 24: 1-8. PMID 25113746 DOI: 10.1093/hmg/ddu414  1
2015 Beauchamp RL, James MF, DeSouza PA, Wagh V, Zhao WN, Jordan JT, Stemmer-Rachamimov A, Plotkin SR, Gusella JF, Haggarty SJ, Ramesh V. A high-throughput kinome screen reveals serum/glucocorticoidregulated kinase 1 as a therapeutic target for NF2-deficient meningiomas Oncotarget. 6: 16981-16997.  1
2014 Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Stemmer-Rachamimov AO, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/s40478-014-0167-x  1
2014 Thibert RL, Duhaime AC, Caruso PA, Stemmer-Rachamimov A. Case 34-2014: A 7-year-old boy with focal seizures and progressive weakness New England Journal of Medicine. 371: 1737-1746. PMID 25354108 DOI: 10.1056/NEJMcpc1305993  1
2014 Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, ... ... Stemmer-Rachamimov AO, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/ajmg.a.36754  1
2014 Pier DB, Nunes FP, Plotkin SR, Stemmer-Rachamimov AO, Kim JC, Shih HA, Brastianos P, Lin AE. Turner syndrome and meningioma: support for a possible increased risk of neoplasia in Turner syndrome. European Journal of Medical Genetics. 57: 269-74. PMID 24675142 DOI: 10.1016/j.ejmg.2014.03.005  1
2014 Antoszczyk S, Spyra M, Mautner VF, Kurtz A, Stemmer-Rachamimov AO, Martuza RL, Rabkin SD. Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus. Neuro-Oncology. 16: 1057-66. PMID 24470552 DOI: 10.1093/neuonc/not317  1
2014 Wu J, Patmore DM, Jousma E, Eaves DW, Breving K, Patel AV, Schwartz EB, Fuchs JR, Cripe TP, Stemmer-Rachamimov AO, Ratner N. EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors. Oncogene. 33: 173-80. PMID 23318430 DOI: 10.1038/onc.2012.579  1
2013 Mehendale RA, Stemmer-Rachamimov AO, Dagi LR. A 50-year-old man with a long-standing, large-angle exotropia and limitation of adduction in the left eye. Digital Journal of Ophthalmology : Djo / Sponsored by Massachusetts Eye and Ear Infirmary. 19: 64-7. PMID 24459459 DOI: 10.5693/djo.03.2013.09.004  1
2013 Mayes DA, Rizvi TA, Titus-Mitchell H, Oberst R, Ciraolo GM, Vorhees CV, Robinson AP, Miller SD, Cancelas JA, Stemmer-Rachamimov AO, Ratner N. Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature. Cell Reports. 4: 1197-212. PMID 24035394 DOI: 10.1016/j.celrep.2013.08.011  1
2013 Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL. The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Science Signaling. 6: ra77. PMID 24003254 DOI: 10.1126/scisignal.2004060  1
2013 Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y, Riedemann L, Taylor J, Ivy P, Duda DG, Ancukiewicz M, Plotkin SR, Chi AS, Gerstner ER, Eichler AF, ... ... Stemmer-Rachamimov AO, et al. Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma. Neuro-Oncology. 15: 1079-87. PMID 23828240 DOI: 10.1093/neuonc/not082  1
2013 Wallace ZS, Carruthers MN, Khosroshahi A, Carruthers R, Shinagare S, Stemmer-Rachamimov A, Deshpande V, Stone JH. IgG4-related disease and hypertrophic pachymeningitis. Medicine. 92: 206-16. PMID 23793110 DOI: 10.1097/MD.0b013e31829cce35  1
2013 Zhang W, Fulci G, Wakimoto H, Cheema TA, Buhrman JS, Jeyaretna DS, Stemmer Rachamimov AO, Rabkin SD, Martuza RL. Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models. Neoplasia (New York, N.Y.). 15: 591-9. PMID 23730207 DOI: 10.1593/neo.13158  0.36
2013 Prabhakar S, Goto J, Zhang X, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO. Stochastic model of Tsc1 lesions in mouse brain. Plos One. 8: e64224. PMID 23696872 DOI: 10.1371/journal.pone.0064224  1
2013 Las Heras F, Martuza R, Caruso P, Rincon S, Stemmer-Rachamimov A. 24-Year-old woman with an internal auditory canal mass Brain Pathology. 23: 361-362. PMID 23587143 DOI: 10.1111/bpa.12055  1
2013 Nunes FP, Merker VL, Jennings D, Caruso PA, di Tomaso E, Muzikansky A, Barker FG, Stemmer-Rachamimov A, Plotkin SR. Bevacizumab treatment for meningiomas in NF2: a retrospective analysis of 15 patients. Plos One. 8: e59941. PMID 23555840 DOI: 10.1371/journal.pone.0059941  1
2013 Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, et al. Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. American Journal of Medical Genetics. Part A. 161: 405-16. PMID 23401320 DOI: 10.1002/ajmg.a.35760  1
2013 Peyre M, Clermont-Taranchon E, Stemmer-Rachamimov A, Kalamarides M. Miniaturized handheld confocal microscopy identifies focal brain invasion in a mouse model of aggressive meningioma Brain Pathology. 23: 371-377. PMID 23356716 DOI: 10.1111/bpa.12039  1
2013 Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nature Genetics. 45: 285-9. PMID 23334667 DOI: 10.1038/ng.2526  1
2013 Prabhakar S, Taherian M, Gianni D, Conlon TJ, Fulci G, Brockmann J, Stemmer-Rachamimov A, Sena-Esteves M, Breakefield XO, Brenner GJ. Regression of schwannomas induced by adeno-associated virus-mediated delivery of caspase-1. Human Gene Therapy. 24: 152-62. PMID 23140466 DOI: 10.1089/hum.2012.094  1
2013 Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C, Volk A, Niwa-Kawakita M, Karboul N, Giovannini M, Kalamarides M. Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation Oncogene. 32: 4264-4272. PMID 23045274 DOI: 10.1038/onc.2012.436  1
2012 Smith MJ, Walker JA, Shen Y, Stemmer-Rachamimov A, Gusella JF, Plotkin SR. Expression of SMARCB1 (INI1) mutations in familial schwannomatosis. Human Molecular Genetics. 21: 5239-45. PMID 22949514 DOI: 10.1093/hmg/dds370  1
2012 Merker VL, Esparza S, Smith MJ, Stemmer-Rachamimov A, Plotkin SR. Clinical features of schwannomatosis: a retrospective analysis of 87 patients. The Oncologist. 17: 1317-22. PMID 22927469 DOI: 10.1634/theoncologist.2012-0162  1
2012 Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J. Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido. The New England Journal of Medicine. 367: 157-69. PMID 22784119 DOI: 10.1056/NEJMcpc1110053  1
2012 Huynh N, Stemmer-Rachamimov AO, Swearingen B, Cestari DM. Decreased vision and junctional scotoma from pituicytoma. Case Reports in Ophthalmology. 3: 190-6. PMID 22740829 DOI: 10.1159/000339242  1
2012 James MF, Stivison E, Beauchamp R, Han S, Li H, Wallace MR, Gusella JF, Stemmer-Rachamimov AO, Ramesh V. Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types. Molecular Cancer Research : McR. 10: 649-59. PMID 22426462 DOI: 10.1158/1541-7786.MCR-11-0425-T  1
2012 Hagel C, Stemmer-Rachamimov AO, Bornemann A, Schuhmann M, Nagel C, Huson S, Evans DG, Plotkin S, Matthies C, Kluwe L, Mautner VF. Clinical presentation, immunohistochemistry and electron microscopy indicate neurofibromatosis type 2-associated gliomas to be spinal ependymomas. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 32: 611-6. PMID 22394059 DOI: 10.1111/j.1440-1789.2012.01306.x  1
2012 Simon MV, Cole AJ, Chang EC, Buchbinder BR, Stufflebeam SM, Nozari A, Stemmer-Rachamimov AO, Eskandar EN. An intraoperative multimodal neurophysiologic approach to successful resection of precentral gyrus epileptogenic lesions. Epilepsia. 53: e75-9. PMID 22309192 DOI: 10.1111/j.1528-1167.2011.03400.x  1
2012 Babovic-Vuksanovic D, Messiaen L, Nagel C, Brems H, Scheithauer B, Denayer E, Mao R, Sciot R, Janowski KM, Schuhmann MU, Claes K, Beert E, Garrity JA, Spinner RJ, Stemmer-Rachamimov A, et al. Multiple orbital neurofibromas, painful peripheral nerve tumors, distinctive face and marfanoid habitus: a new syndrome. European Journal of Human Genetics : Ejhg. 20: 618-25. PMID 22258529 DOI: 10.1038/ejhg.2011.275  1
2012 Fleming AJ, Hukin J, Rassekh R, Fryer C, Kim J, Stemmer-Rachamimov A, Birks DK, Huang A, Yip S, Dunham C. Atypical teratoid rhabdoid tumors (ATRTs): the British Columbia's Children's Hospital's experience, 1986-2006. Brain Pathology (Zurich, Switzerland). 22: 625-35. PMID 22188464 DOI: 10.1111/j.1750-3639.2011.00561.x  1
2012 Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, ... ... Stemmer-Rachamimov AO, et al. Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. American Journal of Medical Genetics. Part A. 158: 24-41. PMID 22140088 DOI: 10.1002/ajmg.a.34359  1
2012 Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, ... ... Stemmer-Rachamimov A, et al. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathologica. 123: 369-80. PMID 22083253 DOI: 10.1007/s00401-011-0905-0  1
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/neuonc/nor195  1
2012 Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA. Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex. Clinical Genetics. 82: 558-63. PMID 22035404 DOI: 10.1111/j.1399-0004.2011.01805.x  1
2012 Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 37-45. PMID 21915104 DOI: 10.1038/mt.2011.187  1
2012 Stemmer-Rachamimov A, Nielsen GP. Pathologic and molecular diagnostic features of peripheral nerve sheath tumors in NF1 Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 429-443. DOI: 10.1007/978-3-642-32864-0_28  1
2011 Bienfang DC, McKenna MJ, Papaliodis GN, Gonzalez RG, Stemmer-Rachamimov A. Case 24-2011: A 36-year-old man with headache, memory loss, and confusion New England Journal of Medicine. 365: 549-559. PMID 21830970 DOI: 10.1056/NEJMcpc1011324  1
2011 Darland DC, Cain JT, Berosik MA, Saint-Geniez M, Odens PW, Schaubhut GJ, Frisch S, Stemmer-Rachamimov A, Darland T, D'Amore PA. Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development. Developmental Biology. 358: 9-22. PMID 21803034 DOI: 10.1016/j.ydbio.2011.06.045  1
2011 Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4484-93. PMID 21558403 DOI: 10.1158/1078-0432.CCR-11-0575  1
2011 Mayes DA, Rizvi TA, Cancelas JA, Kolasinski NT, Ciraolo GM, Stemmer-Rachamimov AO, Ratner N. Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Research. 71: 4675-85. PMID 21551249 DOI: 10.1158/0008-5472.CAN-10-4558  1
2011 Gallagher A, Kovach A, Stemmer-Rachamimov A, Rosenberg AE, Eskandar E, Thiele EA. Metaplastic bone in a cortical tuber of a young patient with tuberous sclerosis complex. Neurology. 76: 1602-4. PMID 21536642 DOI: 10.1212/WNL.0b013e3182190d25  1
2011 Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 19: 527-40. PMID 21481793 DOI: 10.1016/j.ccr.2011.02.017  1
2011 Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, Taranchon E, Han ZY, Martinelli C, Lusis EA, Hegedus B, Gutmann DH, Giovannini M. Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 30: 2333-44. PMID 21242963 DOI: 10.1038/onc.2010.609  1
2011 Rodriguez FJ, Scheithauer BW, George D, Midha R, MacCollin M, Stemmer-Rachamimov AO. Superficial neurofibromas in the setting of schwannomatosis: nosologic implications. Acta Neuropathologica. 121: 663-8. PMID 21191601 DOI: 10.1007/s00401-010-0793-8  1
2011 Saydam O, Senol O, Würdinger T, Mizrak A, Ozdener GB, Stemmer-Rachamimov AO, Yi M, Stephens RM, Krichevsky AM, Saydam N, Brenner GJ, Breakefield XO. miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. Cancer Research. 71: 852-61. PMID 21156648 DOI: 10.1158/0008-5472.CAN-10-1219  1
2011 Jeyaretna DS, Curry WT, Batchelor TT, Stemmer-Rachamimov A, Plotkin SR. Exacerbation of cerebral radiation necrosis by bevacizumab Journal of Clinical Oncology. 29: e159-e162. PMID 21149667 DOI: 10.1200/JCO.2010.31.4815  1
2011 Saydam O, Ozdener GB, Senol O, Mizrak A, Prabhakar S, Stemmer-Rachamimov AO, Breakefield XO, Brenner GJ. A novel imaging-compatible sciatic nerve schwannoma model. Journal of Neuroscience Methods. 195: 75-7. PMID 21111000 DOI: 10.1016/j.jneumeth.2010.10.021  1
2010 Gallagher A, Madan N, Stemmer-Rachamimov A, Thiele EA. Progressive calcified tuber in a young male with tuberous sclerosis complex Developmental Medicine and Child Neurology. 52: 1062-1065. PMID 21175459 DOI: 10.1111/j.1469-8749.2010.03792.x  1
2010 Saydam O, Senol O, Schaaij-Visser TB, Pham TV, Piersma SR, Stemmer-Rachamimov AO, Wurdinger T, Peerdeman SM, Jimenez CR. Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas. Journal of Proteome Research. 9: 485-94. PMID 19877719 DOI: 10.1021/pr900834h  1
2010 Prabhakar S, Brenner GJ, Sung B, Messerli SM, Mao J, Sena-Esteves M, Stemmer-Rachamimov A, Tannous B, Breakefield XO. Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter. Cancer Gene Therapy. 17: 266-74. PMID 19834516 DOI: 10.1038/cgt.2009.71  1
2009 Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, ... ... Stemmer-Rachamimov A, et al. Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. Embo Molecular Medicine. 1: 236-48. PMID 20049725 DOI: 10.1002/emmm.200900027  1
2009 Saydam O, Shen Y, Würdinger T, Senol O, Boke E, James MF, Tannous BA, Stemmer-Rachamimov AO, Yi M, Stephens RM, Fraefel C, Gusella JF, Krichevsky AM, Breakefield XO. Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Molecular and Cellular Biology. 29: 5923-40. PMID 19703993 DOI: 10.1128/MCB.00332-09  1
2009 Shen Y, Nunes F, Stemmer-Rachamimov A, James M, Mohapatra G, Plotkin S, Betensky RA, Engler DA, Roy J, Ramesh V, Gusella JF. Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas. Bmc Medical Genomics. 2: 42. PMID 19589153 DOI: 10.1186/1755-8794-2-42  1
2009 Plotkin SR, Stemmer-Rachamimov AO, Barker FG, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, di Tomaso E. Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. The New England Journal of Medicine. 361: 358-67. PMID 19587327 DOI: 10.1056/NEJMoa0902579  1
2009 McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, ... ... Stemmer-Rachamimov AO, et al. Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell. 16: 44-54. PMID 19573811 DOI: 10.1016/j.ccr.2009.05.009  1
2009 Stankovic KM, Mrugala MM, Martuza RL, Silver M, Betensky RA, Nadol JB, Stemmer-Rachamimov AO. Genetic determinants of hearing loss associated with vestibular schwannomas. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 30: 661-7. PMID 19546833 DOI: 10.1097/MAO.0b013e3181a66ece  1
2009 Sheikh SI, Stemmer-Rachamimov A, Attar EC. Autopsy diagnosis of progressive multifocal leukoencephalopathy with JC virus-negative CSF after cord blood stem-cell transplantation. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e46-7. PMID 19451419 DOI: 10.1200/JCO.2009.22.4451  1
2009 James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V. NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth. Molecular and Cellular Biology. 29: 4250-61. PMID 19451225 DOI: 10.1128/MCB.01581-08  1
2009 Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research. 69: 3472-81. PMID 19351838 DOI: 10.1158/0008-5472.CAN-08-3886  1
2009 Scheithauer BW, Swearingen B, Whyte ET, Auluck PK, Stemmer-Rachamimov AO. Ependymoma of the sella turcica: a variant of pituicytoma. Human Pathology. 40: 435-40. PMID 18992914 DOI: 10.1016/j.humpath.2008.08.013  1
2009 Chang Z, Guo CL, Ahronowitz I, Stemmer-Rachamimov AO, MacCollin M, Nunes FP. A role for the p53 pathway in the pathology of meningiomas with NF2 loss. Journal of Neuro-Oncology. 91: 265-70. PMID 18974932 DOI: 10.1007/s11060-008-9721-3  1
2008 Smith ER, Loeffler J, Misra M, Pomerantz SR, Stemmer-Rachamimov A, Post MD. Case records of the Massachusetts General Hospital. Case 37-2008. A 17-year-old boy with a pituitary tumor and skull abnormalities. The New England Journal of Medicine. 359: 2367-77. PMID 19038883 DOI: 10.1056/NEJMcpc0806983  1
2008 Jones GN, Tep C, Towns WH, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS. Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production. Neoplasia (New York, N.Y.). 10: 1213-21. PMID 18953430 DOI: 10.1593/neo.08652  1
2008 Yi C, Wilker EW, Yaffe MB, Stemmer-Rachamimov A, Kissil JL. Validation of the p21-activated kinases as targets for inhibition in neurofibromatosis type 2 Cancer Research. 68: 7932-7937. PMID 18829550 DOI: 10.1158/0008-5472.CAN-08-0866  1
2008 Snuderl M, Chi SN, De Santis SM, Stemmer-Rachamimov AO, Betensky RA, De Girolami U, Kieran MW. Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas. Journal of Neuropathology and Experimental Neurology. 67: 911-20. PMID 18716553 DOI: 10.1097/NEN.0b013e318184f413  1
2008 Maguire CA, Meijer DH, LeRoy SG, Tierney LA, Broekman ML, Costa FF, Breakefield XO, Stemmer-Rachamimov A, Sena-Esteves M. Preventing growth of brain tumors by creating a zone of resistance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1695-702. PMID 18714312 DOI: 10.1038/mt.2008.168  1
2008 Patil S, Perry A, Maccollin M, Dong S, Betensky RA, Yeh TH, Gutmann DH, Stemmer-Rachamimov AO. Immunohistochemical analysis supports a role for INI1/SMARCB1 in hereditary forms of schwannomas, but not in solitary, sporadic schwannomas. Brain Pathology (Zurich, Switzerland). 18: 517-9. PMID 18422762 DOI: 10.1111/j.1750-3639.2008.00155.x  1
2008 Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell. 13: 105-16. PMID 18242511 DOI: 10.1016/j.ccr.2007.12.027  1
2008 Huang S, Vader D, Wang Z, Stemmer-Rachamimov A, Weitz DA, Dai G, Rosen BR, Deisboeck TS. Using magnetic resonance microscopy to study the growth dynamics of a glioma spheroid in collagen I: A case study. Bmc Medical Imaging. 8: 3. PMID 18230155 DOI: 10.1186/1471-2342-8-3  1
2008 Gabeau-Lacet D, Grant E, Stemmer-Rachamimov A, Yock T, Tarbell NJ. Sellar abnormalities in female first-degree relatives. Clinical Neurology and Neurosurgery. 110: 202-6. PMID 18035480 DOI: 10.1016/j.clineuro.2007.09.021  1
2008 James MF, Lelke JM, Maccollin M, Plotkin SR, Stemmer-Rachamimov AO, Ramesh V, Gusella JF. Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth. Neurobiology of Disease. 29: 278-92. PMID 17962031 DOI: 10.1016/j.nbd.2007.09.002  1
2008 Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathology (Zurich, Switzerland). 18: 62-70. PMID 17924978 DOI: 10.1111/j.1750-3639.2007.00105.x  1
2008 Desantis SM, Houseman EA, Coull BA, Stemmer-Rachamimov A, Betensky RA. A penalized latent class model for ordinal data Biostatistics. 9: 249-262. PMID 17626225 DOI: 10.1093/biostatistics/kxm026  1
2007 Samuels MA, Gonzalez RG, Kim AY, Stemmer-Rachamimov A. Case records of the Massachusetts General Hospital. Case 34-2007. A 77-year-old man with ear pain, difficulty speaking, and altered mental status. The New England Journal of Medicine. 357: 1957-65. PMID 17989389 DOI: 10.1056/NEJMcpc079028  1
2007 Lessell S, Kim JW, Hatton MP, Stemmer-Rachamimov A, Thiagalingham S, Rubin PAD. Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma Journal of Neuro-Ophthalmology. 27: 104-106. PMID 17548993 DOI: 10.1097/WNO.0b013e318064e495  1
2007 Prabhakar S, Messerli SM, Stemmer-Rachamimov AO, Liu TC, Rabkin S, Martuza R, Breakefield XO. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Therapy. 14: 460-7. PMID 17304235 DOI: 10.1038/sj.cgt.7701037  1
2006 O'Neill GN, Gonzalez RG, Cros DP, Ackerman RH, Brown RH, Stemmer-Rachamimov A. Case 22-2006: A 77-year-old man with a rapidly progressive gait disorder New England Journal of Medicine. 355: 296-304. PMID 16855271 DOI: 10.1056/NEJMcpc069013  1
2005 Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery Human Gene Therapy. 16: 1367-1376. PMID 16390268 DOI: 10.1089/hum.2005.16.1367  1
2005 Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH, Louis DN. Histology-based expression profiling yields novel prognostic markers in human glioblastoma. Journal of Neuropathology and Experimental Neurology. 64: 948-55. PMID 16254489  1
2005 Nunes F, Shen Y, Niida Y, Beauchamp R, Stemmer-Rachamimov AO, Ramesh V, Gusella J, MacCollin M. Inactivation patterns of NF2 and DAL-1/4.1B (EPB41L3) in sporadic meningioma. Cancer Genetics and Cytogenetics. 162: 135-9. PMID 16213361 DOI: 10.1016/j.cancergencyto.2005.04.003  1
2005 MacCollin M, Chiocca EA, Evans DG, Friedman JM, Horvitz R, Jaramillo D, Lev M, Mautner VF, Niimura M, Plotkin SR, Sang CN, Stemmer-Rachamimov A, Roach ES. Diagnostic criteria for schwannomatosis. Neurology. 64: 1838-45. PMID 15955931 DOI: 10.1212/01.WNL.0000163982.78900.AD  1
2005 Korf BR, Henson JW, Stemmer-Rachamimov A. Case 13-2005: A 48-year-old man with weakness of the limbs and multiple tumors of spinal nerves New England Journal of Medicine. 352: 1800-1808. PMID 15858190 DOI: 10.1056/NEJMcpc059008  1
2005 Nutt CL, Betensky RA, Brower MA, Batchelor TT, Louis DN, Stemmer-Rachamimov AO. YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2258-64. PMID 15788675 DOI: 10.1158/1078-0432.CCR-04-1601  1
2005 Perry A, Kurtkaya-Yapicier O, Scheithauer BW, Robinson S, Prayson RA, Kleinschmidt-DeMasters BK, Stemmer-Rachamimov AO, Gutmann DH. Insights into meningioangiomatosis with and without meningioma: a clinicopathologic and genetic series of 24 cases with review of the literature. Brain Pathology (Zurich, Switzerland). 15: 55-65. PMID 15779237  1
2004 Lee-Jones L, Aligianis I, Davies PA, Puga A, Farndon PA, Stemmer-Rachamimov A, Ramesh V, Sampson JR. Sacrococcygeal chordomas in patients with tuberous sclerosis complex show somatic loss of TSC1 or TSC2 Genes Chromosomes and Cancer. 41: 80-85. PMID 15236319 DOI: 10.1002/gcc.20052  1
2004 Eckstein O, Stemmer-Rachamimov A, Nunes F, Hoch D, Ojemann R, MacCollin M. Multiple meningiomas in brain and lung due to acquired mutation of the NF2 gene. Neurology. 62: 1904-5. PMID 15159511  1
2004 Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.CAN-03-4079  1
2004 Nestler U, Wakimoto H, Siller-Lopez F, Aguilar LK, Chakravarti A, Muzikansky A, Stemmer-Rachamimov A, Chiocca EA, Aguilar-Cordova E, Hochberg FH. The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects Journal of Neuro-Oncology. 67: 177-188. PMID 15072465 DOI: 10.1023/  1
2004 Han S, Santos TM, Puga A, Roy J, Thiele EA, McCollin M, Stemmer-Rachamimov A, Ramesh V. Phosphorylation of Tuberin as a Novel Mechanism for Somatic Inactivation of the Tuberous Sclerosis Complex Proteins in Brain Lesions Cancer Research. 64: 812-816. PMID 14871804 DOI: 10.1158/0008-5472.CAN-03-3277  1
2003 Heinrich B, Hartmann C, Stemmer-Rachamimov AO, Louis DN, MacCollin M. Multiple meningiomas: Investigating the molecular basis of sporadic and familial forms. International Journal of Cancer. Journal International Du Cancer. 103: 483-8. PMID 12478663 DOI: 10.1002/ijc.10840  1
2001 Niida Y, Stemmer-Rachamimov AO, Logrip M, Tapon D, Perez R, Kwiatkowski DJ, Sims K, MacCollin M, Louis DN, Ramesh V. Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions. American Journal of Human Genetics. 69: 493-503. PMID 11468687 DOI: 10.1086/321972  1
2001 Deisboeck TS, Berens ME, Kansal AR, Torquato S, Stemmer-Rachamimov AO, Chiocca EA. Pattern of self-organization in tumour systems: complex growth dynamics in a novel brain tumour spheroid model. Cell Proliferation. 34: 115-34. PMID 11348426 DOI: 10.1046/j.1365-2184.2001.00202.x  1
2001 Ino Y, Betensky RA, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Ramsay DA, Cairncross JG, Louis DN. Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 839-45. PMID 11309331  1
2001 Murthy V, Stemmer-Rachamimov AO, Haddad LA, Roy JE, Cutone AN, Beauchamp RL, Smith N, Louis DN, Ramesh V. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin. Acta Neuropathologica. 101: 202-10. PMID 11307618  1
2001 Stemmer-Rachamimov AO, Wiederhold T, Nielsen GP, James M, Pinney-Michalowski D, Roy JE, Cohen WA, Ramesh V, Louis DN. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas. The American Journal of Pathology. 158: 57-62. PMID 11141479 DOI: 10.1016/S0002-9440(10)63944-2  1
2001 Ropper AH, Gonzalez RG, Heller HM, Stemmer-Rachamimov A. Weekly clinicopathological exercises New England Journal of Medicine. 345: 126-131. DOI: 10.1056/NEJM200107123450208  1
2000 Ino Y, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Jhung S, Ramsay DA, von Deimling A, Louis DN, Cairncross JG. Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. Journal of Neurosurgery. 92: 983-90. PMID 10839259 DOI: 10.3171/jns.2000.92.6.0983  1
1999 Nielsen GP, Stemmer-Rachamimov AO, Ino Y, Moller MB, Rosenberg AE, Louis DN. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. The American Journal of Pathology. 155: 1879-84. PMID 10595918 DOI: 10.1016/S0002-9440(10)65507-1  1
1999 Nielsen GP, Stemmer-Rachamimov AO, Shaw J, Roy JE, Koh J, Louis DN. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1137-43. PMID 10496532  1
1999 Taylor MD, Perry J, Zlatescu MC, Stemmer-Rachamimov AO, Ang LC, Ino Y, Schwartz M, Becker LE, Louis DN, Cairncross JG. The hPMS2 exon 5 mutation and malignant glioma. Case report. Journal of Neurosurgery. 90: 946-50. PMID 10223463 DOI: 10.3171/jns.1999.90.5.0946  1
1998 Stemmer-Rachamimov AO, Nielsen GP, Rosenberg AE, Louis DN, Jones D, Ramesh V, Gusella JF, Jacoby LB. The NF2 gene and merlin protein in human osteosarcomas. Neurogenetics. 2: 73-4. PMID 9933303 DOI: 10.1007/s100480050054  1
1998 Stemmer-Rachamimov AO, Ino Y, Lim ZY, Jacoby LB, MacCollin M, Gusella JF, Ramesh V, Louis DN. Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2. Journal of Neuropathology and Experimental Neurology. 57: 1164-7. PMID 9862639  1
1998 Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG, Iliopoulos O. The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Molecular Cell. 1: 959-68. PMID 9651579  1
1997 Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, Burwick JA, Pinney D, Beauchamp R, Jacoby LB, Gusella JF, Ramesh V, Louis DN. Universal absence of merlin, but not other ERM family members, in schwannomas. The American Journal of Pathology. 151: 1649-54. PMID 9403715  1
1997 Stemmer-Rachamimov AO, Louis DN. Histopathologic and immunohistochemical prognostic factors in malignant gliomas. Current Opinion in Oncology. 9: 230-4. PMID 9229144  1
1997 Stemmer-Rachamimov AO, Gonzalez-Agosti C, Xu L, Burwick JA, Beauchamp R, Pinney D, Louis DN, Ramesh V. Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 56: 735-42. PMID 9184664  1
1997 Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261  1
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