| Year |
Citation |
Score |
| 2023 |
Høilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village. Ageing Research Reviews. 93: 102173. PMID 38104639 DOI: 10.1016/j.arr.2023.102173 |
0.405 |
|
| 2023 |
Høilund-Carlsen PF, Revheim ME, Costa T, Alavi A, Kepp KP, Sensi SL, Perry G, Robakis NK, Barrio JR, Vissel B. Passive Alzheimer's immunotherapy: A promising or uncertain option? Ageing Research Reviews. 90: 101996. PMID 37414156 DOI: 10.1016/j.arr.2023.101996 |
0.346 |
|
| 2023 |
Kepp KP, Sensi SL, Johnsen KB, Barrio JR, Høilund-Carlsen PF, Neve RL, Alavi A, Herrup K, Perry G, Robakis NK, Vissel B, Espay AJ. The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes. Journal of Alzheimer's Disease : Jad. PMID 37334596 DOI: 10.3233/JAD-230099 |
0.376 |
|
| 2020 |
Yoon Y, Voloudakis G, Doran N, Zhang E, Dimovasili C, Chen L, Shao Z, Darmanis S, Tang C, Tang J, Wang VX, Hof PR, Robakis NK, Georgakopoulos A. PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Molecular Psychiatry. PMID 32541930 DOI: 10.1038/S41380-020-0812-7 |
0.362 |
|
| 2020 |
Robakis NK. What Do Recent Clinical Trials Teach Us About the Etiology of AD. Advances in Experimental Medicine and Biology. 1195: 167. PMID 32468473 DOI: 10.1007/978-3-030-32633-3_23 |
0.4 |
|
| 2020 |
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, Zhuang R, Hou X, Zhang Y, Robakis NK, Li YM, Dordick JS, Ubarretxena-Belandia I, Wang C. Substrate interaction inhibits γ-secretase production of amyloid-β peptides. Chemical Communications (Cambridge, England). PMID 32016207 DOI: 10.1039/C9Cc09170J |
0.365 |
|
| 2019 |
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, Zhuang M, Robakis NK, Li Y, Wang C. SUBSTRATE BINDING INHIBITS γ-SECRETASE CLEAVAGE OF AMYLOID PRECURSOR PROTEIN Alzheimers & Dementia. 15: 1595. DOI: 10.1016/J.Jalz.2019.09.052 |
0.367 |
|
| 2018 |
Warren NA, Voloudakis G, Yoon Y, Robakis NK, Georgakopoulos A. The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis. Cellular and Molecular Life Sciences : Cmls. PMID 29428965 DOI: 10.1007/S00018-018-2762-7 |
0.735 |
|
| 2017 |
Huang Q, Voloudakis G, Ren Y, Yoon Y, Zhang E, Kajiwara Y, Shao Z, Xuan Z, Lebedev D, Georgakopoulos A, Robakis NK. Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28855274 DOI: 10.1096/Fj.201700447Rr |
0.491 |
|
| 2017 |
Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics. PMID 28335009 DOI: 10.1093/Hmg/Ddx103 |
0.319 |
|
| 2016 |
Nikolakopoulou AM, Georgakopoulos A, Robakis NK. Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations. Neurobiology of Aging. 42: 41-9. PMID 27143420 DOI: 10.1016/J.Neurobiolaging.2016.02.028 |
0.339 |
|
| 2016 |
Robakis N. Mechanisms of neuronal death in familial Alzheimer disease and therapeutic implications Neurobiology of Aging. 39: S14. DOI: 10.1016/J.Neurobiolaging.2016.01.069 |
0.304 |
|
| 2015 |
Zhu L, Zhong M, Elder GA, Sano M, Holtzman DM, Gandy S, Cardozo C, Haroutunian V, Robakis NK, Cai D. Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 11965-70. PMID 26372964 DOI: 10.1073/Pnas.1510011112 |
0.362 |
|
| 2015 |
Bruban J, Voloudakis G, Huang Q, Kajiwara Y, Al Rahim M, Yoon Y, Shioi J, Gama Sosa MA, Shao Z, Georgakopoulos A, Robakis NK. Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25985800 DOI: 10.1096/Fj.15-270645 |
0.321 |
|
| 2015 |
Robakis NK. Molecular neuropathology of Alzheimer dementia and therapeutic approaches. Advances in Experimental Medicine and Biology. 822: 1. PMID 25416969 DOI: 10.1007/978-3-319-08927-0_1 |
0.364 |
|
| 2014 |
Robakis NK, Georgakopoulos A. Allelic interference: a mechanism for trans-dominant transmission of loss of function in the neurodegeneration of familial Alzheimer's disease. Neuro-Degenerative Diseases. 13: 126-30. PMID 24081144 DOI: 10.1159/000354241 |
0.442 |
|
| 2014 |
Robakis NK. Cell signaling abnormalities may drive neurodegeneration in familial Alzheimer disease. Neurochemical Research. 39: 570-5. PMID 23436150 DOI: 10.1007/S11064-013-1003-6 |
0.43 |
|
| 2013 |
Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight EM, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich ME, Robakis NK, Gandy SE, Cai D. Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model. The Journal of Biological Chemistry. 288: 32050-63. PMID 24052255 DOI: 10.1074/Jbc.M113.504365 |
0.426 |
|
| 2013 |
Xuan Z, Barthet G, Shioi J, Xu J, Georgakopoulos A, Bruban J, Robakis NK. Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B. The Journal of Biological Chemistry. 288: 30495-501. PMID 24025330 DOI: 10.1074/Jbc.M113.499004 |
0.57 |
|
| 2013 |
Barthet G, Dunys J, Shao Z, Xuan Z, Ren Y, Xu J, Arbez N, Mauger G, Bruban J, Georgakopoulos A, Shioi J, Robakis NK. Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors. Neurobiology of Aging. 34: 499-510. PMID 22475621 DOI: 10.1016/J.Neurobiolaging.2012.02.024 |
0.578 |
|
| 2012 |
Barthet G, Georgakopoulos A, Robakis NK. Cellular mechanisms of γ-secretase substrate selection, processing and toxicity. Progress in Neurobiology. 98: 166-75. PMID 22622135 DOI: 10.1016/J.Pneurobio.2012.05.006 |
0.388 |
|
| 2011 |
Xu J, Xilouri M, Bruban J, Shioi J, Shao Z, Papazoglou I, Vekrellis K, Robakis NK. Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling. Neurobiology of Aging. 32: 2326.e5-16. PMID 21820214 DOI: 10.1016/J.Neurobiolaging.2011.06.017 |
0.336 |
|
| 2011 |
Georgakopoulos A, Xu J, Xu C, Mauger G, Barthet G, Robakis NK. Presenilin1/gamma-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3594-604. PMID 21746865 DOI: 10.1096/Fj.11-187856 |
0.404 |
|
| 2011 |
Robakis NK. Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives. Neurobiology of Aging. 32: 372-9. PMID 20594619 DOI: 10.1016/J.Neurobiolaging.2010.05.022 |
0.437 |
|
| 2010 |
Pimplikar SW, Nixon RA, Robakis NK, Shen J, Tsai LH. Amyloid-independent mechanisms in Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14946-54. PMID 21068297 DOI: 10.1523/Jneurosci.4305-10.2010 |
0.395 |
|
| 2010 |
Robakis NK. Are Abeta and its derivatives causative agents or innocent bystanders in AD? Neuro-Degenerative Diseases. 7: 32-7. PMID 20160455 DOI: 10.1159/000266476 |
0.448 |
|
| 2009 |
Xu J, Litterst C, Georgakopoulos A, Zaganas I, Robakis NK. Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 284: 27220-8. PMID 19661068 DOI: 10.1074/Jbc.M109.048728 |
0.356 |
|
| 2009 |
Eder-Colli L, Abad-Estarlich N, Pannetier C, Vallet PG, Walzer C, Elder GA, Robakis NK, Bouras C, Savioz A. The presenilin-1 familial Alzheimer's disease mutation P117L decreases neuronal differentiation of embryonic murine neural progenitor cells. Brain Research Bulletin. 80: 296-301. PMID 19555743 DOI: 10.1016/J.Brainresbull.2009.06.007 |
0.343 |
|
| 2009 |
Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 731-40. PMID 19387109 DOI: 10.3233/Jad-2009-1021 |
0.492 |
|
| 2009 |
Kouchi Z, Barthet G, Serban G, Georgakopoulos A, Shioi J, Robakis NK. p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide. The Journal of Biological Chemistry. 284: 1954-61. PMID 19008223 DOI: 10.1074/Jbc.M806250200 |
0.66 |
|
| 2008 |
Baki L, Neve RL, Shao Z, Shioi J, Georgakopoulos A, Robakis NK. Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 483-90. PMID 18184791 DOI: 10.1523/Jneurosci.4067-07.2008 |
0.328 |
|
| 2008 |
Shioi J, Kouchi Z, Chan J, Robakis NK. P4-216: The cadherin-binding factor p120 promotes the γ-secretase processing of cadherins but inhibits APP processing and Aβ production Alzheimer's & Dementia. 4: T734-T735. DOI: 10.1016/J.Jalz.2008.05.2284 |
0.314 |
|
| 2008 |
Baki L, Neve RL, Shao Z, Shioi J, Georgakopoulos A, Robakis NK. P4-195: Presenilin1 prevents neurodegeneration by stimulating PI3K/Akt neuroprotective signaling: Effects of PS1 familial Alzheimer's disease mutations Alzheimer's & Dementia. 4: T728-T728. DOI: 10.1016/J.Jalz.2008.05.2262 |
0.327 |
|
| 2007 |
Fassa A, Parisiadou L, Robakis NK, Efthimiopoulos S. Novel processing of Notch 1 within its intracellular domain by a cysteine protease. Neuro-Degenerative Diseases. 4: 148-55. PMID 17596709 DOI: 10.1159/000101839 |
0.764 |
|
| 2007 |
Litterst C, Georgakopoulos A, Shioi J, Ghersi E, Wisniewski T, Wang R, Ludwig A, Robakis NK. Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor. The Journal of Biological Chemistry. 282: 16155-63. PMID 17428795 DOI: 10.1074/Jbc.M611449200 |
0.332 |
|
| 2007 |
Shioi J, Georgakopoulos A, Mehta P, Kouchi Z, Litterst CM, Baki L, Robakis NK. FAD mutants unable to increase neurotoxic Abeta 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta. Journal of Neurochemistry. 101: 674-81. PMID 17254019 DOI: 10.1111/J.1471-4159.2006.04391.X |
0.407 |
|
| 2006 |
Robakis NK. The discovery and mapping to chromosome 21 of the Alzheimer's amyloid gene: history revised. Journal of Alzheimer's Disease : Jad. 10: 453-5. PMID 17183160 DOI: 10.3233/Jad-2006-10417 |
0.389 |
|
| 2006 |
Arnaud L, Robakis NK, Figueiredo-Pereira ME. It may take inflammation, phosphorylation and ubiquitination to 'tangle' in Alzheimer's disease. Neuro-Degenerative Diseases. 3: 313-9. PMID 16954650 DOI: 10.1159/000095638 |
0.39 |
|
| 2006 |
Georgakopoulos A, Litterst C, Ghersi E, Baki L, Xu C, Serban G, Robakis NK. Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling. The Embo Journal. 25: 1242-52. PMID 16511561 DOI: 10.1038/Sj.Emboj.7601031 |
0.609 |
|
| 2006 |
Agiostratidou G, Muros RM, Shioi J, Marambaud P, Robakis NK. The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors. Journal of Neurochemistry. 96: 1182-8. PMID 16417575 DOI: 10.1111/J.1471-4159.2005.03616.X |
0.417 |
|
| 2006 |
Georgakopoulos A, Litterst C, Ghersi E, Baki L, Xu C, Serban G, Robakis NK. O3-03-02: PS1/γ-secretase regulate the EphB-induced Src signaling Alzheimer's & Dementia. 2: S56-S57. DOI: 10.1016/J.Jalz.2006.05.206 |
0.562 |
|
| 2006 |
Robakis NK, Baki L. P3-409: Presenilin FAD mutants promote neurodegeneration and AD pathology by inhibiting the presenilin function in PI3K/Akt signaling Alzheimer's & Dementia. 2: S496-S496. DOI: 10.1016/J.Jalz.2006.05.1680 |
0.338 |
|
| 2006 |
Shioi J, Dolcini V, Baki L, Mehta P, Georgakopoulos T, Robakis NK. P3-220: Test of PI3K/Akt signaling hypothesis for mechanism of AD using unique PS1 FAD mutations that do not affect Aβ42 production Alzheimer's & Dementia. 2: S440-S440. DOI: 10.1016/J.Jalz.2006.05.1489 |
0.33 |
|
| 2005 |
Serban G, Kouchi Z, Baki L, Georgakopoulos A, Litterst CM, Shioi J, Robakis NK. Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability. The Journal of Biological Chemistry. 280: 36007-12. PMID 16126725 DOI: 10.1074/Jbc.M507503200 |
0.628 |
|
| 2004 |
Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Experimental Neurology. 188: 224-37. PMID 15246822 DOI: 10.1016/J.Expneurol.2004.04.002 |
0.326 |
|
| 2004 |
Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK. PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. The Embo Journal. 23: 2586-96. PMID 15192701 DOI: 10.1038/Sj.Emboj.7600251 |
0.354 |
|
| 2004 |
Umehara Y, Yamada S, Nishimura S, Shioi J, Robakis NK, Sugahara K. Chondroitin sulfate of appican, the proteoglycan form of amyloid precursor protein, produced by C6 glioma cells interacts with heparin-binding neuroregulatory factors. Febs Letters. 557: 233-8. PMID 14741373 DOI: 10.1016/S0014-5793(03)01506-0 |
0.353 |
|
| 2004 |
Baki L, Shioi J, Wen P, Shao Z, Gama-Sosa M, Schwarzman A, Neve R, Robakis NK. P4-307 PS1 suppresses apoptosis and prevents Tau hyperphosphorylation via cadherin/PI3K signaling; effects of PS1 FAD mutations Neurobiology of Aging. 25: S562-S563. DOI: 10.1016/S0197-4580(04)81865-7 |
0.302 |
|
| 2004 |
Serban G, Marambaud P, Litterst C, Robakis N. P3-330 γ-secretase processing of VE-cadherin regulates CBP-mediated transcription Neurobiology of Aging. 25: S449. DOI: 10.1016/S0197-4580(04)81480-5 |
0.571 |
|
| 2004 |
Agiostratidou G, Minana R, Shoi J, Robakis NK. P1-232 The E-cadherin intracellular fragment, released by the γ-secretase-like cleavage, stimulates degradation of the precursors of Abeta peptide Neurobiology of Aging. 25: S162. DOI: 10.1016/S0197-4580(04)80545-1 |
0.344 |
|
| 2004 |
Robakis NK. PL-4-1 Alzheimer's disease: emerging pathogenic mechanisms based on inhibition of PS1 function in signal transduction Neurobiology of Aging. 25: S66. DOI: 10.1016/S0197-4580(04)80222-7 |
0.334 |
|
| 2004 |
Marambaud P, Wen PH, Dutt A, Shioi J, Serban G, Takashima A, Siman R, Robakis NK. O3-05-02 FAD-linked presenilin-1 mutations affect the N-cadherin/CBP signaling pathway via a loss-of-function mechanism Neurobiology of Aging. 25: S61-S62. DOI: 10.1016/S0197-4580(04)80207-0 |
0.566 |
|
| 2003 |
Qin W, Ho L, Pompl PN, Peng Y, Zhao Z, Xiang Z, Robakis NK, Shioi J, Suh J, Pasinetti GM. Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. The Journal of Biological Chemistry. 278: 50970-7. PMID 14507922 DOI: 10.1074/Jbc.M307699200 |
0.411 |
|
| 2003 |
Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell. 114: 635-45. PMID 13678586 DOI: 10.1016/J.Cell.2003.08.008 |
0.357 |
|
| 2003 |
Robakis NK. An Alzheimer's disease hypothesis based on transcriptional dysregulation. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 10: 80-5. PMID 12964415 DOI: 10.3109/13506120309041729 |
0.379 |
|
| 2002 |
Wen PH, Shao X, Shao Z, Hof PR, Wisniewski T, Kelley K, Friedrich VL, Ho L, Pasinetti GM, Shioi J, Robakis NK, Elder GA. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice. Neurobiology of Disease. 10: 8-19. PMID 12079399 DOI: 10.1006/Nbdi.2002.0490 |
0.326 |
|
| 2002 |
Bussière T, Friend PD, Sadeghi N, Wicinski B, Lin GI, Bouras C, Giannakopoulos P, Robakis NK, Morrison JH, Perl DP, Hof PR. Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease. Neuroscience. 112: 75-91. PMID 12044473 DOI: 10.1016/S0306-4522(02)00056-8 |
0.335 |
|
| 2002 |
Marambaud P, Shioi J, Serban G, Georgakopoulos A, Sarner S, Nagy V, Baki L, Wen P, Efthimiopoulos S, Shao Z, Wisniewski T, Robakis NK. A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. The Embo Journal. 21: 1948-56. PMID 11953314 DOI: 10.1093/Emboj/21.8.1948 |
0.748 |
|
| 2002 |
Wen PH, Friedrich VL, Shioi J, Robakis NK, Elder GA. Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice. Neuroscience Letters. 318: 53-6. PMID 11796184 DOI: 10.1016/S0304-3940(01)02485-5 |
0.313 |
|
| 2001 |
Tsuchida K, Shioi J, Yamada S, Boghosian G, Wu A, Cai H, Sugahara K, Robakis NK. Appican, the proteoglycan form of the amyloid precursor protein, contains chondroitin sulfate E in the repeating disaccharide region and 4-O-sulfated galactose in the linkage region. The Journal of Biological Chemistry. 276: 37155-60. PMID 11479316 DOI: 10.1074/Jbc.M105818200 |
0.36 |
|
| 2001 |
Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich VL, Robakis NK. Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Proceedings of the National Academy of Sciences of the United States of America. 98: 2381-6. PMID 11226248 DOI: 10.1073/Pnas.041603398 |
0.678 |
|
| 2000 |
Georgakopoulos A, Marambaud P, Friedrich VL, Shioi J, Efthimiopoulos S, Robakis NK. Presenilin-1: a component of synaptic and endothelial adherens junctions. Annals of the New York Academy of Sciences. 920: 209-14. PMID 11193152 DOI: 10.1111/J.1749-6632.2000.Tb06924.X |
0.613 |
|
| 2000 |
Blitzer RD, Wong T, Giovannini MG, Pangalos MN, Robakis NK, Landau EM. Amyloid beta peptides activate the phosphoinositide signaling pathway in oocytes expressing rat brain RNA. Brain Research. Molecular Brain Research. 76: 115-20. PMID 10719221 DOI: 10.1016/S0169-328X(99)00340-X |
0.412 |
|
| 2000 |
Robakis N, Marambaud P, Baki L, Georgakopoulos A, Shioi J, Serhan G, Cui W, Efthimiopoulos S. Presenilin-1 is a component of synaptic and endothelial adherens junctions: Implications for FAD Neurobiology of Aging. 21: 70. DOI: 10.1016/S0197-4580(00)82533-6 |
0.617 |
|
| 2000 |
Baki L, Marambaud P, Efthimiopoulos S, Wen P, Georgakopoulos T, Robakis NK. PS1 is a regulatory component of the cadherin/catenin adherens junction system Neurobiology of Aging. 21: 68. DOI: 10.1016/S0197-4580(00)82527-0 |
0.627 |
|
| 2000 |
Georgakopoulos T, Shioi J, Gordon R, Holstein GR, Martinelli G, Efthimiopoulos S, Friedrich VL, Robakis NK. Localization of presenilin at synaptic sites Neurobiology of Aging. 21: 182. DOI: 10.1016/S0197-4580(00)82160-0 |
0.609 |
|
| 2000 |
Marambaud P, Baki L, Georgakopoulos A, Shioi J, Efthimiopoulos S, Ozawa M, Robakis NK. Molecular organization of presenilin 1 in the E-cadherin/catenins cell adhesion system Neurobiology of Aging. 21: 181. DOI: 10.1016/S0197-4580(00)82151-X |
0.629 |
|
| 1999 |
Omar RA, Chyan YJ, Andorn AC, Poeggeler B, Robakis NK, Pappolla MA. Increased Expression but Reduced Activity of Antioxidant Enzymes in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 1: 139-145. PMID 12213999 DOI: 10.3233/Jad-1999-1301 |
0.56 |
|
| 1999 |
Georgakopoulos A, Marambaud P, Efthimiopoulos S, Shioi J, Cui W, Li HC, Schütte M, Gordon R, Holstein GR, Martinelli G, Mehta P, Friedrich VL, Robakis NK. Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Molecular Cell. 4: 893-902. PMID 10635315 DOI: 10.1016/S1097-2765(00)80219-1 |
0.67 |
|
| 1999 |
Giannakopoulos P, Kövari E, Buée L, Shioi J, Hof PR, Robakis NK, Bouras C. Presenilin-1 expression in Pick's disease. Acta Neuropathologica. 98: 488-92. PMID 10541872 DOI: 10.1007/S004010051114 |
0.348 |
|
| 1999 |
Robakis NK, Efthimiopoulos S. Familial Alzheimer disease: changes in Abeta production may indicate a disturbance in protein transport or function caused by pleiotropic effects of FAD mutations. Neurobiology of Aging. 20: 81-3; discussion 87. PMID 10466898 DOI: 10.1016/S0197-4580(99)00011-1 |
0.643 |
|
| 1999 |
Figueiredo-Pereira ME, Efthimiopoulos S, Tezapsidis N, Buku A, Ghiso J, Mehta P, Robakis NK. Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins Abeta1-40 and Abeta1-42, respectively. Journal of Neurochemistry. 72: 1417-22. PMID 10098844 DOI: 10.1046/J.1471-4159.1999.721417.X |
0.709 |
|
| 1999 |
Hook VY, Sei C, Yasothornsrikul S, Toneff T, Kang YH, Efthimiopoulos S, Robakis NK, Van Nostrand W. The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles. The Journal of Biological Chemistry. 274: 3165-72. PMID 9915856 DOI: 10.1074/jbc.274.5.3165 |
0.676 |
|
| 1998 |
Efthimiopoulos S, Floor E, Georgakopoulos A, Shioi J, Cui W, Yasothornsrikul S, Hook VY, Wisniewski T, Buee L, Robakis NK. Enrichment of presenilin 1 peptides in neuronal large dense-core and somatodendritic clathrin-coated vesicles. Journal of Neurochemistry. 71: 2365-72. PMID 9832134 DOI: 10.1046/J.1471-4159.1998.71062365.X |
0.671 |
|
| 1998 |
Bursztajn S, DeSouza R, McPhie DL, Berman SA, Shioi J, Robakis NK, Neve RL. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9790-9. PMID 9822738 DOI: 10.1523/Jneurosci.18-23-09790.1998 |
0.36 |
|
| 1998 |
Pappolla M, Bozner P, Soto C, Shao H, Robakis NK, Zagorski M, Frangione B, Ghiso J. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. The Journal of Biological Chemistry. 273: 7185-8. PMID 9516407 DOI: 10.1074/Jbc.273.13.7185 |
0.627 |
|
| 1998 |
Tezapsidis N, Li HC, Ripellino JA, Efthimiopoulos S, Vassilacopoulou D, Sambamurti K, Toneff T, Yasothornsrikul S, Hook VY, Robakis NK. Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes. Biochemistry. 37: 1274-82. PMID 9477953 DOI: 10.1021/Bi9714159 |
0.671 |
|
| 1998 |
Neve RL, Robakis NK. Alzheimer's disease: a re-examination of the amyloid hypothesis. Trends in Neurosciences. 21: 15-9. PMID 9464679 DOI: 10.1016/S0166-2236(97)01168-5 |
0.391 |
|
| 1997 |
Wu A, Pangalos MN, Efthimiopoulos S, Shioi J, Robakis NK. Appican expression induces morphological changes in C6 glioma cells and promotes adhesion of neural cells to the extracellular matrix. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4987-93. PMID 9185536 DOI: 10.1523/Jneurosci.17-13-04987.1997 |
0.667 |
|
| 1997 |
Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DL, Reiter RJ, Efthimiopoulos S, Robakis NK. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1683-90. PMID 9030627 DOI: 10.1523/Jneurosci.17-05-01683.1997 |
0.753 |
|
| 1997 |
Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DLM, Reiter RJ, Efthimiopoulos S, Robakis NK. Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide The Journal of Neuroscience. 17: 1683-1690. DOI: 10.1523/JNEUROSCI.17-05-01683.1997 |
0.587 |
|
| 1996 |
Pangalos MN, Shioi J, Efthimiopoulos S, Wu A, Robakis NK. Characterization of appican, the chondroitin sulfate proteoglycan form of the Alzheimer amyloid precursor protein. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 445-51. PMID 9117561 DOI: 10.1006/Neur.1996.0061 |
0.712 |
|
| 1996 |
Elder GA, Tezapsidis N, Carter J, Shioi J, Bouras C, Li HC, Johnston JM, Efthimiopoulos S, Friedrich VL, Robakis NK. Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains. Journal of Neuroscience Research. 45: 308-20. PMID 8841992 DOI: 10.1002/(Sici)1097-4547(19960801)45:3<308::Aid-Jnr13>3.0.Co;2-# |
0.64 |
|
| 1996 |
Efthimiopoulos S, Punj S, Manolopoulos V, Pangalos M, Wang GP, Refolo LM, Robakis NK. Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein. Journal of Neurochemistry. 67: 872-5. PMID 8764618 DOI: 10.1046/J.1471-4159.1996.67020872.X |
0.697 |
|
| 1996 |
Efthimiopoulos S, Vassilacopoulou D, Ripellino JA, Tezapsidis N, Robakis NK. Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 8046-50. PMID 8755600 DOI: 10.1073/Pnas.93.15.8046 |
0.71 |
|
| 1996 |
Shioi J, Pangalos MN, Wu A, Robakis NK. Structure and function of appican, the proteoglycan form of the alzheimer amyloid precursor Trends in Glycoscience and Glycotechnology. 8: 253-263. DOI: 10.4052/Tigg.8.253 |
0.4 |
|
| 1996 |
Pappolla M, Sos M, Reiter R, Sambamurti K, Omar R, Robakis N, Efthimiopoulos S. 589 Melatonin prevents oxidative damage and heat-shock protein induction in cultured cells exposed to the Alzheimer's amyloid beta protein (Aβ) Neurobiology of Aging. 17: S146-S147. DOI: 10.1016/S0197-4580(96)80591-4 |
0.76 |
|
| 1996 |
Vassilacopoulou D, Efthimiopoulos S, Koliopoulou P, Robakis N. 396 Soluble full length app in synaptosomes and biological fluids Neurobiology of Aging. 17: S99. DOI: 10.1016/S0197-4580(96)80398-8 |
0.624 |
|
| 1996 |
Robakis N, Elder G, Tezapsidis N, Carter J, Shioi J, Bourse C, Eflhimiopoulos S. 148 Identification and brain expression of the S182/presenilin I. Relationship to APP processing Neurobiology of Aging. 17: S38. DOI: 10.1016/S0197-4580(96)80150-3 |
0.307 |
|
| 1996 |
Shioi J, Tezapsidis N, Carter J, Elder G, Li D, Efthimiopoulos S, Friedrich V, Robakis N. 64 Identification of neuron specific expression of the S182/presenilin I protein Neurobiology of Aging. 17: S16. DOI: 10.1016/S0197-4580(96)80066-2 |
0.646 |
|
| 1995 |
Shioi J, Pangalos MN, Ripellino JA, Vassilacopoulou D, Mytilineou C, Margolis RU, Robakis NK. The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures. The Journal of Biological Chemistry. 270: 11839-44. PMID 7744833 DOI: 10.1074/Jbc.270.20.11839 |
0.391 |
|
| 1995 |
Pangalos MN, Efthimiopoulos S, Shioi J, Robakis NK. The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene. The Journal of Biological Chemistry. 270: 10388-91. PMID 7737970 DOI: 10.1074/Jbc.270.18.10388 |
0.708 |
|
| 1995 |
Vassilacopoulou D, Ripellino JA, Tezapsidis N, Hook VY, Robakis NK. Full-length and truncated Alzheimer amyloid precursors in chromaffin granules: solubilization of membrane amyloid precursor is mediated by an enzymatic mechanism. Journal of Neurochemistry. 64: 2140-6. PMID 7722498 DOI: 10.1046/J.1471-4159.1995.64052140.X |
0.431 |
|
| 1995 |
Pappolla MA, Sambamurti K, Efthimiopoulos S, Refolo L, Omar RA, Robakis NK. Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins. Neuroscience Letters. 192: 105-8. PMID 7675314 DOI: 10.1016/0304-3940(95)11627-9 |
0.738 |
|
| 1995 |
Pangalos MN, Shioi J, Robakis NK. Expression of the chondroitin sulfate proteoglycans of amyloid precursor (appican) and amyloid precursor-like protein 2. Journal of Neurochemistry. 65: 762-9. PMID 7616233 DOI: 10.1046/J.1471-4159.1995.65020762.X |
0.451 |
|
| 1995 |
Refolo LM, Sambamurti K, Efthimiopoulos S, Pappolla MA, Robakis NK. Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization. Journal of Neuroscience Research. 40: 694-706. PMID 7602619 DOI: 10.1002/Jnr.490400515 |
0.742 |
|
| 1994 |
Efthimiopoulos S, Felsenstein KM, Sambamurti K, Robakis NK, Refolo LM. Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of a cholera toxin sensitive protein. Journal of Neuroscience Research. 38: 81-90. PMID 8057394 DOI: 10.1002/Jnr.490380111 |
0.673 |
|
| 1994 |
Robakis NK, Pappolla MA. Oxygen-free radicals and amyloidosis in Alzheimer's disease: is there a connection? Neurobiology of Aging. 15: 457-9; discussion 47. PMID 7969722 DOI: 10.1016/0197-4580(94)90077-9 |
0.566 |
|
| 1994 |
Robakis NK, Pangalos MN. Involvement of amyloid as a central step in the development of Alzheimer's disease. Neurobiology of Aging. 15: S127-9. PMID 7700436 DOI: 10.1016/0197-4580(94)90189-9 |
0.372 |
|
| 1994 |
Ripellino JA, Vassilacopoulou D, Robakis NK. Solubilization of full-length amyloid precursor proteins from PC12 cell membranes. Journal of Neuroscience Research. 39: 211-8. PMID 7530778 DOI: 10.1002/jnr.490390211 |
0.326 |
|
| 1993 |
Shioi J, Refolo LM, Efthimiopoulos S, Robakis NK. Chondroitin sulfate proteoglycan form of cellular and cell-surface Alzheimer amyloid precursor. Neuroscience Letters. 154: 121-4. PMID 8361624 DOI: 10.1016/0304-3940(93)90186-O |
0.712 |
|
| 1993 |
Robakis NK, Vassilacopoulou D, Efthimiopoulos S, Sambamurti K, Refolo LM, Shioi J. Cellular processing and proteoglycan nature of amyloid precursor proteins. Annals of the New York Academy of Sciences. 695: 132-8. PMID 8239271 DOI: 10.1111/J.1749-6632.1993.Tb23041.X |
0.721 |
|
| 1992 |
Shioi J, Anderson JP, Ripellino JA, Robakis NK. Chondroitin sulfate proteoglycan form of the Alzheimer's beta-amyloid precursor. The Journal of Biological Chemistry. 267: 13819-22. PMID 1629183 |
0.336 |
|
| 1992 |
Sambamurti K, Shioi J, Anderson JP, Pappolla MA, Robakis NK. Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells. Journal of Neuroscience Research. 33: 319-29. PMID 1453494 DOI: 10.1002/jnr.490330216 |
0.61 |
|
| 1992 |
Pappolla MA, Omar RA, Sambamurti K, Anderson JP, Robakis NK. The genesis of the senile plaque. Further evidence in support of its neuronal origin. The American Journal of Pathology. 141: 1151-9. PMID 1443049 |
0.589 |
|
| 1992 |
Anderson JP, Chen Y, Kim KS, Robakis NK. An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence. Journal of Neurochemistry. 59: 2328-31. PMID 1431910 |
0.37 |
|
| 1992 |
Vallet PG, Guntern R, Hof PR, Golaz J, Delacourte A, Robakis NK, Bouras C. A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease. Acta Neuropathologica. 83: 170-8. PMID 1373017 DOI: 10.1007/Bf00308476 |
0.348 |
|
| 1992 |
Pappolla MA, Omar RA, Kim KS, Robakis NK. Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. The American Journal of Pathology. 140: 621-8. PMID 1372157 |
0.592 |
|
| 1992 |
Sambamurti K, Refolo LM, Shioi J, Pappolla MA, Robakis NK. The Alzheimer's amyloid precursor is cleaved intracellularly in the trans-Golgi network or in a post-Golgi compartment. Annals of the New York Academy of Sciences. 674: 118-28. PMID 1283818 DOI: 10.1111/j.1749-6632.1992.tb27481.x |
0.575 |
|
| 1991 |
Anderson JP, Esch FS, Keim PS, Sambamurti K, Lieberburg I, Robakis NK. Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neuroscience Letters. 128: 126-8. PMID 1922940 DOI: 10.1016/0304-3940(91)90775-O |
0.314 |
|
| 1991 |
Robakis NK, Anderson JP, Refolo LM, Wallace W. Expression of the Alzheimer amyloid precursor in brain tissue and effects of NGF and EGF on its metabolism. Clinical Neuropharmacology. 14: S15-23. PMID 1913706 DOI: 10.1097/00002826-199114001-00004 |
0.409 |
|
| 1991 |
Probst A, Langui D, Ipsen S, Robakis N, Ulrich J. Deposition of beta/A4 protein along neuronal plasma membranes in diffuse senile plaques. Acta Neuropathologica. 83: 21-9. PMID 1724335 DOI: 10.1007/Bf00294426 |
0.35 |
|
| 1991 |
Refolo LM, Wittenberg IS, Friedrich VL, Robakis NK. The Alzheimer amyloid precursor is associated with the detergent-insoluble cytoskeleton. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3888-97. PMID 1683901 DOI: 10.1523/Jneurosci.11-12-03888.1991 |
0.463 |
|
| 1990 |
Berkenbosch F, Refolo LM, Friedrich VL, Casper D, Blum M, Robakis NK. The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia. Journal of Neuroscience Research. 25: 431-40. PMID 2109094 DOI: 10.1002/Jnr.490250321 |
0.399 |
|
| 1990 |
Brown HR, Goller NL, Rudelli RD, Merz GS, Wolfe GC, Wisniewski HM, Robakis NK. The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells. Acta Neuropathologica. 80: 1-6. PMID 1972856 DOI: 10.1007/Bf00294214 |
0.502 |
|
| 1989 |
Jenkins EC, Devine-Gage EA, Yao XL, Houck GE, Brown WT, Robakis NK, Wisniewski KE, Silverman WP, Reisberg B, Wisniewski HM. Beta-amyloid protein probe hybridized to chromosome 9 in 3 Alzheimer disease individuals. Progress in Clinical and Biological Research. 317: 269-75. PMID 2690102 DOI: 10.1097/00002093-198802030-00134 |
0.499 |
|
| 1989 |
Anderson JP, Refolo LM, Wallace W, Mehta P, Krishnamurthi M, Gotlib J, Bierer L, Haroutunian V, Perl D, Robakis NK. Differential brain expression of the Alzheimer's amyloid precursor protein. The Embo Journal. 8: 3627-32. PMID 2583112 DOI: 10.1002/J.1460-2075.1989.Tb08536.X |
0.316 |
|
| 1989 |
La Fauci G, Lahiri DK, Salton SR, Robakis NK. Characterization of the 5'-end region and the first two exons of the beta-protein precursor gene. Biochemical and Biophysical Research Communications. 159: 297-304. PMID 2538123 DOI: 10.1016/0006-291X(89)92437-6 |
0.34 |
|
| 1989 |
Refolo LM, Salton SR, Anderson JP, Mehta P, Robakis NK. Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures. Biochemical and Biophysical Research Communications. 164: 664-70. PMID 2510719 DOI: 10.1016/0006-291X(89)91511-8 |
0.385 |
|
| 1989 |
Wallace W, Krishnamurthi M, Gotlib J, Refolo L, Haroutunian V, Robakis NK. Characterization of newly synthesized beta-amyloid precursor protein in rat and human Biological Psychiatry. 25: A118. DOI: 10.1016/0006-3223(89)91724-1 |
0.357 |
|
| 1989 |
Anderson JP, Refolo LM, Haroutunian V, Bierer L, Perl D, Robakis NK, Davis KL. Processing and regional specificity of variant forms of the Alzheimer amyloid precursor protein Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91721-6 |
0.399 |
|
| 1989 |
Robakis N, Refolo L, Salton S, Anderson J. Effects of nerve growth factor on the expression and post-translational processing of the beta-amyloid precursor proteins in PC12 cells Biological Psychiatry. 25: A116. DOI: 10.1016/0006-3223(89)91720-4 |
0.364 |
|
| 1988 |
Jenkins EC, Devine-Gage EA, Robakis NK, Yao XL, Brown WT, Houck GE, Wolfe G, Ramakrishna N, Silverman WP, Wisniewski HM. Fine mapping of an Alzheimer disease-associated gene encoding beta-amyloid protein. Biochemical and Biophysical Research Communications. 151: 1-8. PMID 3279948 DOI: 10.1016/0006-291X(88)90551-7 |
0.534 |
|
| 1988 |
Wu Y, Dobkin C, Devine-Gage E, Ramakrishna N, Brown WT, Wisniewski HM, Robakis NK. A high frequency NcoI RFLP detected in the Alzheimer amyloid peptide gene. Nucleic Acids Research. 16: 1647. PMID 2894637 DOI: 10.1093/nar/16.4.1647 |
0.425 |
|
| 1988 |
WALLACE W, ANDERSON J, HAROTUNIAN V, ROBAKIS NK. CHARACTERIZATION OF PROTEIN SYNTHESIS DURING ALZHEIMER??S DISEASE Alzheimer Disease & Associated Disorders. 2: 282. DOI: 10.1097/00002093-198802030-00131 |
0.345 |
|
| 1988 |
Lafauci G, Lahiri D, Refolo L, Wallace W, Anderson J, Mehta P, Robakis NK. STRUCTURAL AND EXPRESSION STUDIES OF THE ALZHEIMER AMYLOID PRECURSOR Alzheimer Disease & Associated Disorders. 2: 279. DOI: 10.1097/00002093-198802030-00128 |
0.369 |
|
| 1988 |
Devine-Gage EA, Jenkins EC, Brown WT, Robakis NK, Wisniewski HM. The genetics of Familial Alzheimer's Disease Age. 11: 98-102. DOI: 10.1007/Bf02431747 |
0.504 |
|
| 1987 |
Robakis NK, Ramakrishna N, Wolfe G, Wisniewski HM. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proceedings of the National Academy of Sciences of the United States of America. 84: 4190-4. PMID 3035574 DOI: 10.1073/Pnas.84.12.4190 |
0.515 |
|
| 1987 |
Reeves RH, Robakis NK, Oster-Granite ML, Wisniewski HM, Coyle JT, Gearhart JD. Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man. Brain Research. 388: 215-21. PMID 2960420 DOI: 10.1016/0169-328X(87)90028-3 |
0.495 |
|
| 1987 |
David F, Robakis NK, Lucotte G. A new TaqI polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease. Nucleic Acids Research. 15: 9103. PMID 2891111 DOI: 10.1093/Nar/15.21.9103 |
0.395 |
|
| 1987 |
Jenkins EC, Devine-Gage EA, Yao XL, Houck GE, Brown WT, Wisniewski HM, Robakis NK. In-situ hybridisation of the beta-amyloid protein probe to chromosome 9 in patients with familial Alzheimer's disease. Lancet. 2: 1155-6. PMID 2890057 DOI: 10.1016/S0140-6736(87)91591-1 |
0.469 |
|
| 1987 |
Wu Y, Brown WT, Robakis NK, Dobkin C, Devine-Gage E, Merz P, Wisniewski HM. A PvuII RFLP detected in the human prion protein (PrP) gene. Nucleic Acids Research. 15: 3191. PMID 2882483 DOI: 10.1093/Nar/15.7.3191 |
0.446 |
|
| 1987 |
Robakis NK, Wisniewski HM, Jenkins EC, Devine-Gage EA, Houck GE, Yao XL, Ramakrishna N, Wolfe G, Silverman WP, Brown WT. Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome. Lancet. 1: 384-5. PMID 2880184 DOI: 10.1016/S0140-6736(87)91754-5 |
0.454 |
|
| 1986 |
Robakis NK, Sawh PR, Wolfe GC, Rubenstein R, Carp RI, Innis MA. Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues. Proceedings of the National Academy of Sciences of the United States of America. 83: 6377-81. PMID 3529083 DOI: 10.1073/Pnas.83.17.6377 |
0.311 |
|
| 1986 |
Kascsak RJ, Rubenstein R, Merz PA, Carp RI, Robakis NK, Wisniewski HM, Diringer H. Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains. Journal of Virology. 59: 676-83. PMID 2426470 |
0.364 |
|
| 1986 |
Rubenstein R, Kascsak RJ, Merz PA, Papini MC, Carp RI, Robakis NK, Wisniewski HM. Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations. The Journal of General Virology. 67: 671-81. PMID 2420924 DOI: 10.1099/0022-1317-67-4-671 |
0.476 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1991 |
Wallace WC, Bragin V, Robakis NK, Sambamurti K, VanderPutten D, Merril CR, Davis KL, Santucci AC, Haroutunian V. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Research. Molecular Brain Research. 10: 173-8. PMID 1649369 DOI: 10.1016/0169-328X(91)90108-A |
0.298 |
|
| 1996 |
Pasinetti G, Mall N, Shioi J, Tezapsidis N, Li H, Robakis N. 550 Expression of Presenilin 1 (PS-1; S182) in response to experimental lesion models of Alzheimer disease Neurobiology of Aging. 17: S137. DOI: 10.1016/S0197-4580(96)80552-5 |
0.295 |
|
| 1982 |
Peacock S, Cenatiempo Y, Robakis N, Brot N, Weissbach H. In vitro synthesis of the first dipeptide of the beta subunit of Escherichia coli RNA polymerase Proceedings of the National Academy of Sciences of the United States of America. 79: 4609-4612. PMID 6289308 DOI: 10.1073/Pnas.79.15.4609 |
0.292 |
|
| 1994 |
Roberts SB, Ripellino JA, Ingalls KM, Robakis NK, Felsenstein KM. Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase. The Journal of Biological Chemistry. 269: 3111-6. PMID 8300647 |
0.289 |
|
| 1982 |
Cenatiempo Y, Robakis N, Meza-Basso L, Brot N, Weissbach H, Reid BR. Use of different tRNASer isoacceptor species in vitro to discriminate between the expression of plasmid genes. Proceedings of the National Academy of Sciences of the United States of America. 79: 1466-8. PMID 6803242 DOI: 10.1073/Pnas.79.5.1466 |
0.289 |
|
| 2011 |
Barthet G, Shioi J, Shao Z, Ren Y, Georgakopoulos A, Robakis NK. Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2937-46. PMID 21597003 DOI: 10.1096/fj.11-183806 |
0.285 |
|
| 2016 |
Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, ... Robakis NK, et al. Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia. Science Signaling. 9: ra5. PMID 26758213 DOI: 10.1126/Scisignal.Aab0467 |
0.282 |
|
| 1986 |
Robakis NK, Devine-Gage EA, Jenkins EC, Kascsak RJ, Brown WT, Krawczun MS, Silverman WP. Localization of a human gene homologous to the PrP gene on the p arm of chromosome 20 and detection of PrP-related antigens in normal human brain. Biochemical and Biophysical Research Communications. 140: 758-65. PMID 2877664 DOI: 10.1016/0006-291X(86)90796-5 |
0.279 |
|
| 2010 |
Robakis NK. Alzheimer's disease: new light on etiology and management. The Mount Sinai Journal of Medicine, New York. 77: 1-2. PMID 20101717 DOI: 10.1002/Msj.20166 |
0.273 |
|
| 1983 |
Robakis N, Cenatiempo Y, Meza-Basso L, Brot N, Weissbach H. A coupled DNA-directed in vitro system to study gene expression based on di- and tripeptide formation. Methods in Enzymology. 101: 690-706. PMID 6310342 DOI: 10.1016/0076-6879(83)01048-4 |
0.272 |
|
| 1992 |
Bouras C, Giannakopoulos P, Hof P, Robakis N, Delacourte A, Surini M, Michel J. Neuropathological study of 21 centenarians Neurobiology of Aging. 13: S39. DOI: 10.1016/0197-4580(92)90280-B |
0.272 |
|
| 2011 |
Michailidis IE, Rusinova R, Georgakopoulos A, Chen Y, Iyengar R, Robakis NK, Logothetis DE, Baki L. Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. Pflã¼Gers Archiv : European Journal of Physiology. 461: 387-97. PMID 21107857 DOI: 10.1007/S00424-010-0904-3 |
0.271 |
|
| 1991 |
Lahiri DK, Robakis NK. The promoter activity of the gene encoding Alzheimer beta-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences. Brain Research. Molecular Brain Research. 9: 253-7. PMID 1851527 DOI: 10.1016/0169-328X(91)90009-M |
0.27 |
|
| 2005 |
Marambaud P, Robakis NK. Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation. Genes, Brain, and Behavior. 4: 134-46. PMID 15810902 DOI: 10.1111/j.1601-183X.2005.00086.x |
0.268 |
|
| 1981 |
Robakis N, Meza-Basso L, Brot N, Weissbach H. Translational control of ribosomal protein L10 synthesis occurs prior to formation of first peptide bond Proceedings of the National Academy of Sciences of the United States of America. 78: 4261-4264. PMID 7027258 DOI: 10.1073/Pnas.78.7.4261 |
0.261 |
|
| 1992 |
Roch JM, Shapiro IP, Sundsmo MP, Otero DA, Refolo LM, Robakis NK, Saitoh T. Bacterial expression, purification, and functional mapping of the amyloid beta/A4 protein precursor. The Journal of Biological Chemistry. 267: 2214-21. PMID 1346393 |
0.258 |
|
| 2021 |
Robakis NK. On the Nomenclature of the Alzheimer's Disease Amyloid and Its Precursor1. Journal of Alzheimer's Disease : Jad. PMID 34420977 DOI: 10.3233/JAD-215138 |
0.256 |
|
| 1990 |
Harris MS, Devine-Gage E, Robakis NK. An AluI RFLP detected in the human prion protein (PrP) gene. Nucleic Acids Research. 18: 385. PMID 1970165 DOI: 10.1093/Nar/18.2.385-A |
0.256 |
|
| 1987 |
Warren AC, Robakis NK, Ramakrishna N, Koo EH, Ross CA, Robb AS, Folstein MF, Price DL, Antonarakis SE. beta-Amyloid gene is not present in three copies in autopsy-validated Alzheimer's disease. Genomics. 1: 307-12. PMID 2966761 DOI: 10.1016/0888-7543(87)90029-2 |
0.253 |
|
| 1993 |
Buée L, Ding W, Anderson JP, Narindrasorasak S, Kisilevsky R, Boyle NJ, Robakis NK, Delacourte A, Greenberg B, Fillit HM. Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide. Brain Research. 627: 199-204. PMID 8298962 DOI: 10.1016/0006-8993(93)90321-D |
0.252 |
|
| 1987 |
David F, Robakis NK, Lucotte G. A new TaqI polymorphism detected by the cDNA encoding amyloid beta protein of alzhemer's disease Nucleic Acids Research. 15: 9103. DOI: 10.1093/nar/15.21.9103 |
0.249 |
|
| 2013 |
Alonso Adel C, ElAkkad E, Gong C, Liu F, Tanaka T, Kudo T, Tatebayashi Y, Pei J, Wang J, Khatoon S, Flory M, Ghetti B, Gozes I, Novak M, Novak M, ... Robakis NK, et al. Inge Grundke-Iqbal, Ph.D. (1937–2012): the discoverer of the abnormal hyperphosphorylation of tau in Alzheimer’s disease. Journal of Molecular Neuroscience : Mn. 49: 430-5. PMID 24883456 DOI: 10.1007/S12031-012-9925-Z |
0.247 |
|
| 2010 |
Shioi J, Xu J, Lan P, Georgakopoulos A, Robakis NK. P2-302: Progranulin activates MAP kinase and protects neurons against glutamate toxicity and oxidative stress Alzheimer's & Dementia. 6: S402-S402. DOI: 10.1016/J.Jalz.2010.05.1353 |
0.246 |
|
| 2004 |
Shioi J, Baki L, Wen P, Shao Z, Davies P, Robakis NK. P4-320 Role of presenilin 1 and its FAD mutations in cadherin/PI3K/AKT pathway investigated in animal models Neurobiology of Aging. 25: S566. DOI: 10.1016/S0197-4580(04)81878-5 |
0.245 |
|
| 2023 |
Kepp KP, Robakis NK, Høilund-Carlsen PF, Sensi SL, Vissel B. The amyloid cascade hypothesis: an updated critical review. Brain : a Journal of Neurology. PMID 37183523 DOI: 10.1093/brain/awad159 |
0.244 |
|
| 1989 |
Altstiel LD, Robakis NK. Expression of beta-amyloid precursor protein on neuron plasma membranes Biological Psychiatry. 25: A118-A119. DOI: 10.1016/0006-3223(89)91725-3 |
0.235 |
|
| 2004 |
Georgakopoulos A, Litterst C, Xu C, Wen P, Shao Z, Robakis N. P4-301 Presenilin-1/gamma secretase cleavage of ephrinb ligands and EPHB receptors Neurobiology of Aging. 25: S560-S561. DOI: 10.1016/S0197-4580(04)81859-1 |
0.233 |
|
| 2014 |
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, ... ... Robakis NK, et al. A role for noncoding variation in schizophrenia. Cell Reports. 9: 1417-29. PMID 25453756 DOI: 10.1016/J.Celrep.2014.10.015 |
0.231 |
|
| 1990 |
Robakis NK, Altstiel LD, Refolo LM, Anderson JP. Function and metabolism of the protease inhibitor-containing Alzheimer amyloid precursors Molecular Biology and Genetics of Alzheimer's Disease: Proceedings of the International Symposium On Dementia: Molecular Biology and Genetics of Alzheimer's Disease. Ics884. 179-188. |
0.23 |
|
| 1997 |
Giannakopoulos P, Bouras C, Kövari E, Shioi J, Tezapsidis N, Hof PR, Robakis NK. Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease. The American Journal of Pathology. 150: 429-36. PMID 9033258 |
0.229 |
|
| 2000 |
Shioi J, Tsuchida K, Yamada S, Sugahara K, Boghosian G, Wu A, Cai H, Robakis NK. Chemical characterization of appican's chondrotin sulfate glycosaminoglycan chains Neurobiology of Aging. 21: 183. DOI: 10.1016/S0197-4580(00)82164-8 |
0.222 |
|
| 2020 |
Al Rahim M, Yoon Y, Dimovasili C, Shao Z, Huang Q, Zhang E, Kezunovic N, Chen L, Schaffner A, Huntley GW, Ubarretxena-Belandia I, Georgakopoulos A, Robakis NK. Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of -methyl-d-aspartate receptor. Brain Communications. 2: fcaa100. PMID 33005890 DOI: 10.1093/braincomms/fcaa100 |
0.217 |
|
| 1990 |
Robakis NK, Mohamadi M, Fu DY, Sambamurti K, Refolo LM. Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region. Nucleic Acids Research. 18: 1299. PMID 2138729 DOI: 10.1093/Nar/18.5.1299 |
0.214 |
|
| 2022 |
Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, et al. Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling. Nature Cell Biology. PMID 36456828 DOI: 10.1038/s41556-022-01031-6 |
0.213 |
|
| 2011 |
Roussos P, Giakoumaki SG, Georgakopoulos A, Robakis NK, Bitsios P. The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males. Bipolar Disorders. 13: 250-9. PMID 21676128 DOI: 10.1111/J.1399-5618.2011.00924.X |
0.201 |
|
| 1995 |
Robakis NK. Molecular biology of Alzheimer's disease pathology Journal of Neuropathology and Experimental Neurology. 54: 16S-17S. |
0.186 |
|
| 1987 |
Robakis NK, Ramakrishna N, Wolfe G, Wisniewski HM, Iqbal K. CLONING AND CHARACTERIZATION OF A cDNA ENCODING THE ALZHEIMERʼS DISEASE AND DOWNʼS SYNDROME AMYLOID PEPTIDE Journal of Neuropathology and Experimental Neurology. 46: 396. DOI: 10.1097/00005072-198705000-00200 |
0.182 |
|
| 2007 |
Robakis NK. Alzheimer research forum discussion: Gain or loss of function - Time to shake up assumptions on γ-secretase in Alzheimer disease? Commentary Journal of Alzheimer's Disease. 11: 401. |
0.179 |
|
| 1996 |
Bouras C, Giannakopoulos P, Schioi J, Tezapsidis N, Robakis NK. Presenilin-1 polymorphism and Alzheimer's disease. Lancet. 347: 1185-6. PMID 8609782 |
0.172 |
|
| 1996 |
Kehoe P, Williams J, Lovestone S, Wilcock G, Owen MJ, Holmans P, Liddell M, Holmes C, Powall J, Neal J, Bouras C, Giannakopoulos P, Schioi J, Tezapsidis N, Robakis NK, et al. Presenilin-1 polymorphism and Alzheimer's disease [6] Lancet. 347: 185-187. |
0.172 |
|
| 2006 |
Wollmer MA, Nitsch RM, Hock C, Papassotiropoulos A, Marlowe L, Peila R, Benke KS, Figueiredo-Pereira ME, Robakis NK, Hardy J, White LR, Wu YR, Arnaud L, Gibbs JR, Launer LJ, et al. Subject Index Vol. 3, 2006 Complexus. 3: 254-254. DOI: 10.1159/000098409 |
0.168 |
|
| 2006 |
Wollmer MA, Nitsch RM, Hock C, Papassotiropoulos A, Marlowe L, Peila R, Benke KS, Figueiredo-Pereira ME, Robakis NK, Hardy J, White LR, Wu YR, Arnaud L, Gibbs JR, Launer LJ, et al. Contents Vol. 3, 2006 Neurodegenerative Diseases. 3: 359-360. DOI: 10.1159/000098410 |
0.163 |
|
| 1992 |
Roch JM, Shapiro IP, Sundsmo MP, Otero DAC, Refolo LM, Robakis NK, Saitoh T. Bacterial expression, purification, and functional mapping of the amyloid β/A4 protein precursor Journal of Biological Chemistry. 267: 2214-2221. |
0.159 |
|
| 1994 |
Shashidharan P, Michaelidis TM, Robakis NK, Kresovali A, Papamatheakis J, Plaitakis A. Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. The Journal of Biological Chemistry. 269: 16971-6. PMID 8207021 |
0.148 |
|
| 1983 |
Robakis NK, Rossman TG, Shapiro R, Szer W. The effects of bisulfite on growth and macromolecular synthesis in Escherichia coli. Chemico-Biological Interactions. 43: 289-98. PMID 6402316 DOI: 10.1016/0009-2797(83)90113-8 |
0.142 |
|
| 1983 |
Robakis NK, Shapiro R, Szer W. Reversal of growth inhibition in Escherichia coli by bisulfite. Chemico-Biological Interactions. 43: 299-311. PMID 6337733 DOI: 10.1016/0009-2797(83)90114-X |
0.129 |
|
| 2006 |
Robakis NK, Marambaud P. The Presenilin/γ-Secretase Complex Regulates Production of Transcriptional Factors: Effects of FAD Mutations Transcription Factors in the Nervous System: Development, Brain Function, and Diseases. 398-416. DOI: 10.1002/3527608036.ch19 |
0.125 |
|
| 1990 |
Harris MS, Devine-Gage E, Robakis NK. An Alul RFLP detected in the human prion protein (PrP) gene Nucleic Acids Research. 18: 385. |
0.109 |
|
| 2013 |
del Carmen Alonso A, ElAkkad E, Gong C, Liu F, Tanaka T, Kudo T, Tatebayashi Y, Pei J, Wang J, Khatoon S, Flory M, Ghetti B, Gozes I, Novak M, Novak M, ... Robakis NK, et al. Erratum to: Inge Grundke-Iqbal, Ph.D. (1937–2012): the Discoverer of the Abnormal Hyperphosphorylation of Tau in Alzheimer’s Disease Journal of Molecular Neuroscience. 49: 639-640. DOI: 10.1007/s12031-013-9963-1 |
0.094 |
|
| 1995 |
Fu D, Skryabin BV, Brosius J, Robakis NK. Molecular cloning and characterization of the mouse dopamine D3 receptor gene: an additional intron and an mRNA variant. Dna and Cell Biology. 14: 485-92. PMID 7598803 |
0.082 |
|
| 2013 |
Bruban J, Shioi J, Lan P, Xu J, Robakis N. P3-038: A novel PKC-dependent phosphorylation of doublecortin: Potential implications in the context of excitotoxicity Alzheimer's & Dementia. 9: P565-P565. DOI: 10.1016/j.jalz.2013.05.1107 |
0.079 |
|
| 2021 |
Yoon Y, Voloudakis G, Doran N, Zhang E, Dimovasili C, Chen L, Shao Z, Darmanis S, Tang C, Tang J, Wang VX, Hof PR, Robakis NK, Georgakopoulos A. Detection of brain neovascularization induced by focal ischemia. Molecular Psychiatry. 26: 1719. PMID 34522038 DOI: 10.1038/s41380-021-01279-8 |
0.076 |
|
| 2018 |
Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics. PMID 29982455 DOI: 10.1093/hmg/ddy229 |
0.06 |
|
| 1999 |
Jung MY, Skryabin BV, Arai M, Abbondanzo S, Fu D, Brosius J, Robakis NK, Polites HG, Pintar JE, Schmauss C. Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors. Neuroscience. 91: 911-24. PMID 10391470 DOI: 10.1016/S0306-4522(98)00705-2 |
0.043 |
|
| 1982 |
Robakis N, Boublik M. Conformation of free and ribosome bound rRNAs and E. coli. Biochemical and Biophysical Research Communications. 103: 1401-8. PMID 7037005 DOI: 10.1016/0006-291X(81)90279-5 |
0.043 |
|
| 2011 |
Roussos P, Giakoumaki SG, Adamaki E, Georgakopoulos A, Anastasios G, Robakis NK, Nikos RK, Bitsios P. The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1677-88. PMID 21471957 DOI: 10.1038/npp.2011.49 |
0.028 |
|
| 1985 |
ROBAKIS NK, PALLERONI NJ, DESPREAUX CW, BOUBLIK M, BAKER CA, CHURN PJ, CLAUS GW. Isolation and Characterization of two Phages for Gluconobacter oxydans Microbiology. 131: 2467-2473. DOI: 10.1099/00221287-131-9-2467 |
0.025 |
|
| 1985 |
Robakis NK, Palleroni NJ, Despreaux CW. Isolation and characterization of two phages of Gluconobacter oxydans Journal of General Microbiology. 131: 2467-2473. |
0.025 |
|
| 1985 |
Robakis NK, Palleroni NJ, Boublik M, Despreaux CW. Construction of a restriction map of the Gluconobacter bacteriophage A-1 genome Journal of General Microbiology. 131: 2475-2477. |
0.017 |
|
| Hide low-probability matches. |