Spiros Efthimiopoulos - Publications

Affiliations: 
University of Athens, Athens, Greece 

57/67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chatzistavraki M, Papazafiri P, Efthimiopoulos S. Amyloid-β Protein Precursor Regulates Depolarization-Induced Calcium-Mediated Synaptic Signaling in Brain Slices. Journal of Alzheimer's Disease : Jad. PMID 32597808 DOI: 10.3233/Jad-200290  0.355
2019 Efthimiopoulos S, Chatzistavraki M, Papazafiri P. Amyloid precursor protein regulates depolarization-induced calcium-mediated signaling in brain slices Ibro Reports. 6. DOI: 10.1016/J.Ibror.2019.07.754  0.349
2018 Thysiadis S, Katsamakas S, Mpousis S, Avramidis N, Efthimiopoulos S, Sarli V. Design and synthesis of gallocyanine inhibitors of DKK1/LRP6 interactions for treatment of Alzheimer's disease. Bioorganic Chemistry. 80: 230-244. PMID 29966869 DOI: 10.1016/J.Bioorg.2018.06.018  0.307
2017 Matis I, Delivoria DC, Mavroidi B, Papaevgeniou N, Panoutsou S, Bellou S, Papavasileiou KD, Linardaki ZI, Stavropoulou AV, Vekrellis K, Boukos N, Kolisis FN, Gonos ES, Margarity M, Papadopoulos MG, ... Efthimiopoulos S, et al. An integrated bacterial system for the discovery of chemical rescuers of disease-associated protein misfolding. Nature Biomedical Engineering. 1: 838-852. PMID 31015593 DOI: 10.1038/S41551-017-0144-3  0.395
2017 Mavroeidi P, Mavrofrydi O, Pappa E, Panopoulou M, Papazafiri P, Haralambous S, Efthimiopoulos S. Oxygen and Glucose Deprivation Alter Synaptic Distribution of Tau Protein: The Role of Phosphorylation. Journal of Alzheimer's Disease : Jad. PMID 28869464 DOI: 10.3233/Jad-170157  0.305
2016 Stavropoulou AV, Mavrofrydi O, Saftig P, Efthimiopoulos S. Serum starvation induces BACE1 processing and secretion. Current Alzheimer Research. PMID 27784219 DOI: 10.2174/1567205013666161026091530  0.418
2015 Mpousis S, Thysiadis S, Avramidis N, Katsamakas S, Efthimiopoulos S, Sarli V. Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies. European Journal of Medicinal Chemistry. 108: 28-38. PMID 26629858 DOI: 10.1016/J.Ejmech.2015.11.024  0.326
2015 Kyratzi E, Liakos A, Papadogiannaki G, Efthimiopoulos S. Structural and regulatory elements of the interaction between amyloid-β protein precursor and Homer3. Journal of Alzheimer's Disease : Jad. 45: 147-57. PMID 25589726 DOI: 10.3233/Jad-141992  0.422
2014 Kyratzi E, Efthimiopoulos S. Calcium regulates the interaction of amyloid precursor protein with Homer3 protein. Neurobiology of Aging. 35: 2053-63. PMID 24792907 DOI: 10.1016/J.Neurobiolaging.2014.03.019  0.38
2013 Tsachaki M, Fotinopoulou A, Slavi N, Zarkou V, Ghiso J, Efthimiopoulos S. BRI2 interacts with BACE1 and regulates its cellular levels by promoting its degradation and reducing its mRNA levels. Current Alzheimer Research. 10: 532-41. PMID 23701002 DOI: 10.2174/1567205011310050009  0.421
2013 Tsachaki M, Fotinopoulou A, Slavi N, Zarkou V, Ghiso J, Efthimiopoulos S. BRI2 Interacts with BACE1 and Reduces its Cellular Levels by Reducing the Levels of BACE1 mRNA and Inducing its Degradation Through the Lysosomal Pathway. Current Alzheimer Research. PMID 23627710  0.303
2013 Chatzistavraki M, Kyratzi E, Fotinopoulou A, Papazafiri P, Efthimiopoulos S. Downregulation of AβPP enhances both calcium content of endoplasmic reticulum and acidic stores and the dynamics of store operated calcium channel activity. Journal of Alzheimer's Disease : Jad. 34: 407-15. PMID 23241555 DOI: 10.3233/Jad-121768  0.333
2012 Papandreou MA, Tsachaki M, Efthimiopoulos S, Klimis-Zacas D, Margarity M, Lamari FN. Cell-line specific protection by berry polyphenols against hydrogen peroxide challenge and lack of effect on metabolism of amyloid precursor protein. Phytotherapy Research : Ptr. 26: 956-63. PMID 22086824 DOI: 10.1002/Ptr.3670  0.395
2011 Tsachaki M, Serlidaki D, Fetani A, Zarkou V, Rozani I, Ghiso J, Efthimiopoulos S. Glycosylation of BRI2 on asparagine 170 is involved in its trafficking to the cell surface but not in its processing by furin or ADAM10. Glycobiology. 21: 1382-8. PMID 21752865 DOI: 10.1093/Glycob/Cwr097  0.399
2010 Tsachaki M, Ghiso J, Rostagno A, Efthimiopoulos S. BRI2 homodimerizes with the involvement of intermolecular disulfide bonds. Neurobiology of Aging. 31: 88-98. PMID 18440095 DOI: 10.1016/J.Neurobiolaging.2008.03.004  0.398
2008 Tsachaki M, Ghiso J, Efthimiopoulos S. BRI2 as a central protein involved in neurodegeneration. Biotechnology Journal. 3: 1548-54. PMID 19072909 DOI: 10.1002/Biot.200800247  0.473
2008 Parisiadou L, Bethani I, Michaki V, Krousti K, Rapti G, Efthimiopoulos S. Homer2 and Homer3 interact with amyloid precursor protein and inhibit Abeta production. Neurobiology of Disease. 30: 353-64. PMID 18387811 DOI: 10.1016/J.Nbd.2008.02.004  0.769
2007 Talamagas AA, Efthimiopoulos S, Tsilibary EC, Figueiredo-Pereira ME, Tzinia AK. Abeta(1-40)-induced secretion of matrix metalloproteinase-9 results in sAPPalpha release by association with cell surface APP. Neurobiology of Disease. 28: 304-15. PMID 17761425 DOI: 10.1016/J.Nbd.2007.07.016  0.381
2007 Fassa A, Parisiadou L, Robakis NK, Efthimiopoulos S. Novel processing of Notch 1 within its intracellular domain by a cysteine protease. Neuro-Degenerative Diseases. 4: 148-55. PMID 17596709 DOI: 10.1159/000101839  0.753
2007 Parisiadou L, Efthimiopoulos S. Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha. Neurobiology of Aging. 28: 377-88. PMID 16458391 DOI: 10.1016/J.Neurobiolaging.2005.12.015  0.769
2006 Papandreou MA, Kanakis CD, Polissiou MG, Efthimiopoulos S, Cordopatis P, Margarity M, Lamari FN. Inhibitory activity on amyloid-beta aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents. Journal of Agricultural and Food Chemistry. 54: 8762-8. PMID 17090119 DOI: 10.1021/jf061932a  0.308
2006 Tsachaki M, Fotinopoulou A, Vlavaki M, Poulopoulos A, Rostagno A, Frangione B, Ghiso J, Efthimiopoulos S. O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation Alzheimer's & Dementia. 2: S36-S36. DOI: 10.1016/J.Jalz.2006.05.125  0.685
2005 Fassa A, Mehta P, Efthimiopoulos S. Notch 1 interacts with the amyloid precursor protein in a Numb-independent manner. Journal of Neuroscience Research. 82: 214-24. PMID 16175584 DOI: 10.1002/Jnr.20642  0.389
2005 Fotinopoulou A, Tsachaki M, Vlavaki M, Poulopoulos A, Rostagno A, Frangione B, Ghiso J, Efthimiopoulos S. BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production. The Journal of Biological Chemistry. 280: 30768-72. PMID 16027166 DOI: 10.1074/Jbc.C500231200  0.743
2004 Parisiadou L, Fassa A, Fotinopoulou A, Bethani I, Efthimiopoulos S. Presenilin 1 and cadherins: stabilization of cell-cell adhesion and proteolysis-dependent regulation of transcription. Neuro-Degenerative Diseases. 1: 184-91. PMID 16908988 DOI: 10.1159/000080984  0.769
2004 Braungart E, Gerlach M, Riederer P, Baumeister R, Hoener MC, Silva OABdCe, Vieira SI, Silva EFdCe, Froelich-Fabre S, Skoglund L, Ostojic J, Kilander L, Lindau M, Rebelo S, Hartmann D, ... ... Efthimiopoulos S, et al. DIADEM / Participants Directory Neurodegenerative Diseases. 1: 243-244. DOI: 10.1159/000082213  0.658
2002 Marambaud P, Shioi J, Serban G, Georgakopoulos A, Sarner S, Nagy V, Baki L, Wen P, Efthimiopoulos S, Shao Z, Wisniewski T, Robakis NK. A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. The Embo Journal. 21: 1948-56. PMID 11953314 DOI: 10.1093/Emboj/21.8.1948  0.705
2001 Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich VL, Robakis NK. Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Proceedings of the National Academy of Sciences of the United States of America. 98: 2381-6. PMID 11226248 DOI: 10.1073/Pnas.041603398  0.61
2000 Georgakopoulos A, Marambaud P, Friedrich VL, Shioi J, Efthimiopoulos S, Robakis NK. Presenilin-1: a component of synaptic and endothelial adherens junctions. Annals of the New York Academy of Sciences. 920: 209-14. PMID 11193152 DOI: 10.1111/J.1749-6632.2000.Tb06924.X  0.518
2000 Robakis N, Marambaud P, Baki L, Georgakopoulos A, Shioi J, Serhan G, Cui W, Efthimiopoulos S. Presenilin-1 is a component of synaptic and endothelial adherens junctions: Implications for FAD Neurobiology of Aging. 21: 70. DOI: 10.1016/S0197-4580(00)82533-6  0.523
2000 Baki L, Marambaud P, Efthimiopoulos S, Wen P, Georgakopoulos T, Robakis NK. PS1 is a regulatory component of the cadherin/catenin adherens junction system Neurobiology of Aging. 21: 68. DOI: 10.1016/S0197-4580(00)82527-0  0.54
2000 Georgakopoulos T, Shioi J, Gordon R, Holstein GR, Martinelli G, Efthimiopoulos S, Friedrich VL, Robakis NK. Localization of presenilin at synaptic sites Neurobiology of Aging. 21: 182. DOI: 10.1016/S0197-4580(00)82160-0  0.513
2000 Marambaud P, Baki L, Georgakopoulos A, Shioi J, Efthimiopoulos S, Ozawa M, Robakis NK. Molecular organization of presenilin 1 in the E-cadherin/catenins cell adhesion system Neurobiology of Aging. 21: 181. DOI: 10.1016/S0197-4580(00)82151-X  0.545
1999 Georgakopoulos A, Marambaud P, Efthimiopoulos S, Shioi J, Cui W, Li HC, Schütte M, Gordon R, Holstein GR, Martinelli G, Mehta P, Friedrich VL, Robakis NK. Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Molecular Cell. 4: 893-902. PMID 10635315 DOI: 10.1016/S1097-2765(00)80219-1  0.604
1999 Robakis NK, Efthimiopoulos S. Familial Alzheimer disease: changes in Abeta production may indicate a disturbance in protein transport or function caused by pleiotropic effects of FAD mutations. Neurobiology of Aging. 20: 81-3; discussion 87. PMID 10466898 DOI: 10.1016/S0197-4580(99)00011-1  0.563
1999 Dowjat WK, Wisniewski T, Efthimiopoulos S, Wisniewski HM. Inhibition of neurite outgrowth by familial Alzheimer's disease-linked presenilin-1 mutations. Neuroscience Letters. 267: 141-4. PMID 10400232 DOI: 10.1016/S0304-3940(99)00351-1  0.531
1999 Figueiredo-Pereira ME, Efthimiopoulos S, Tezapsidis N, Buku A, Ghiso J, Mehta P, Robakis NK. Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins Abeta1-40 and Abeta1-42, respectively. Journal of Neurochemistry. 72: 1417-22. PMID 10098844 DOI: 10.1046/J.1471-4159.1999.721417.X  0.658
1999 Hook VY, Sei C, Yasothornsrikul S, Toneff T, Kang YH, Efthimiopoulos S, Robakis NK, Van Nostrand W. The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles. The Journal of Biological Chemistry. 274: 3165-72. PMID 9915856 DOI: 10.1074/jbc.274.5.3165  0.609
1998 Efthimiopoulos S, Floor E, Georgakopoulos A, Shioi J, Cui W, Yasothornsrikul S, Hook VY, Wisniewski T, Buee L, Robakis NK. Enrichment of presenilin 1 peptides in neuronal large dense-core and somatodendritic clathrin-coated vesicles. Journal of Neurochemistry. 71: 2365-72. PMID 9832134 DOI: 10.1046/J.1471-4159.1998.71062365.X  0.587
1998 Wisniewski T, Dowjat WK, Buxbaum JD, Khorkova O, Efthimiopoulos S, Kulczycki J, Lojkowska W, Wegiel J, Wisniewski HM, Frangione B. A novel Polish presenilin-1 mutation (P117L) is associated with familial Alzheimer's disease and leads to death as early as the age of 28 years. Neuroreport. 9: 217-21. PMID 9507958 DOI: 10.1097/00001756-199801260-00008  0.531
1998 Tezapsidis N, Li HC, Ripellino JA, Efthimiopoulos S, Vassilacopoulou D, Sambamurti K, Toneff T, Yasothornsrikul S, Hook VY, Robakis NK. Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes. Biochemistry. 37: 1274-82. PMID 9477953 DOI: 10.1021/Bi9714159  0.603
1997 Wu A, Pangalos MN, Efthimiopoulos S, Shioi J, Robakis NK. Appican expression induces morphological changes in C6 glioma cells and promotes adhesion of neural cells to the extracellular matrix. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4987-93. PMID 9185536 DOI: 10.1523/Jneurosci.17-13-04987.1997  0.603
1997 Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DL, Reiter RJ, Efthimiopoulos S, Robakis NK. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1683-90. PMID 9030627 DOI: 10.1523/Jneurosci.17-05-01683.1997  0.725
1996 Pangalos MN, Shioi J, Efthimiopoulos S, Wu A, Robakis NK. Characterization of appican, the chondroitin sulfate proteoglycan form of the Alzheimer amyloid precursor protein. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 445-51. PMID 9117561 DOI: 10.1006/Neur.1996.0061  0.656
1996 Elder GA, Tezapsidis N, Carter J, Shioi J, Bouras C, Li HC, Johnston JM, Efthimiopoulos S, Friedrich VL, Robakis NK. Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains. Journal of Neuroscience Research. 45: 308-20. PMID 8841992 DOI: 10.1002/(Sici)1097-4547(19960801)45:3<308::Aid-Jnr13>3.0.Co;2-#  0.571
1996 Efthimiopoulos S, Punj S, Manolopoulos V, Pangalos M, Wang GP, Refolo LM, Robakis NK. Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein. Journal of Neurochemistry. 67: 872-5. PMID 8764618 DOI: 10.1046/J.1471-4159.1996.67020872.X  0.637
1996 Efthimiopoulos S, Vassilacopoulou D, Ripellino JA, Tezapsidis N, Robakis NK. Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 8046-50. PMID 8755600 DOI: 10.1073/Pnas.93.15.8046  0.657
1996 Pappolla M, Sos M, Reiter R, Sambamurti K, Omar R, Robakis N, Efthimiopoulos S. 589 Melatonin prevents oxidative damage and heat-shock protein induction in cultured cells exposed to the Alzheimer's amyloid beta protein (Aβ) Neurobiology of Aging. 17: S146-S147. DOI: 10.1016/S0197-4580(96)80591-4  0.722
1996 Vassilacopoulou D, Efthimiopoulos S, Koliopoulou P, Robakis N. 396 Soluble full length app in synaptosomes and biological fluids Neurobiology of Aging. 17: S99. DOI: 10.1016/S0197-4580(96)80398-8  0.534
1996 Shioi J, Tezapsidis N, Carter J, Elder G, Li D, Efthimiopoulos S, Friedrich V, Robakis N. 64 Identification of neuron specific expression of the S182/presenilin I protein Neurobiology of Aging. 17: S16. DOI: 10.1016/S0197-4580(96)80066-2  0.549
1995 Pangalos MN, Efthimiopoulos S, Shioi J, Robakis NK. The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene. The Journal of Biological Chemistry. 270: 10388-91. PMID 7737970 DOI: 10.1074/Jbc.270.18.10388  0.651
1995 Pappolla MA, Sambamurti K, Efthimiopoulos S, Refolo L, Omar RA, Robakis NK. Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins. Neuroscience Letters. 192: 105-8. PMID 7675314 DOI: 10.1016/0304-3940(95)11627-9  0.718
1995 Refolo LM, Sambamurti K, Efthimiopoulos S, Pappolla MA, Robakis NK. Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization. Journal of Neuroscience Research. 40: 694-706. PMID 7602619 DOI: 10.1002/Jnr.490400515  0.723
1994 Efthimiopoulos S, Felsenstein KM, Sambamurti K, Robakis NK, Refolo LM. Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of a cholera toxin sensitive protein. Journal of Neuroscience Research. 38: 81-90. PMID 8057394 DOI: 10.1002/Jnr.490380111  0.646
1993 Shioi J, Refolo LM, Efthimiopoulos S, Robakis NK. Chondroitin sulfate proteoglycan form of cellular and cell-surface Alzheimer amyloid precursor. Neuroscience Letters. 154: 121-4. PMID 8361624 DOI: 10.1016/0304-3940(93)90186-O  0.666
1993 Robakis NK, Vassilacopoulou D, Efthimiopoulos S, Sambamurti K, Refolo LM, Shioi J. Cellular processing and proteoglycan nature of amyloid precursor proteins. Annals of the New York Academy of Sciences. 695: 132-8. PMID 8239271 DOI: 10.1111/J.1749-6632.1993.Tb23041.X  0.671
1991 Efthimiopoulos S, Giompres P, Valcana T. Kinetics of dopamine and noradrenaline transport in synaptosomes from cerebellum, striatum and frontal cortex of normal and reeler mice. Journal of Neuroscience Research. 29: 510-9. PMID 1838778 DOI: 10.1002/jnr.490290411  0.602
Low-probability matches (unlikely to be authored by this person)
2018 Matis I, Delivoria DC, Mavroidi B, Papaevgeniou N, Panoutsou S, Bellou S, Papavasileiou KD, Linardaki ZI, Stavropoulou AV, Vekrellis K, Boukos N, Kolisis FN, Gonos ES, Margarity M, Papadopoulos MG, ... Efthimiopoulos S, et al. Publisher Correction: An integrated bacterial system for the discovery of chemical rescuers of disease-associated protein misfolding. Nature Biomedical Engineering. 2: 49. PMID 31015658 DOI: 10.1038/S41551-017-0164-Z  0.293
2011 Papandreou MA, Tsachaki M, Efthimiopoulos S, Cordopatis P, Lamari FN, Margarity M. Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection. Behavioural Brain Research. 219: 197-204. PMID 21238492 DOI: 10.1016/J.Bbr.2011.01.007  0.263
1996 Fagarasan MO, Efthimiopoulos S. Mechanism of amyloid beta-peptide (1-42) toxicity in PC12 cells. Molecular Psychiatry. 1: 398-403. PMID 9154234  0.256
1996 Fagarasan M, Efthimiopoulos S. 421 The mechanism of amyloid β-Peptide (1–42) toxicity in PC12 cells Neurobiology of Aging. 17: S105. DOI: 10.1016/S0197-4580(96)80423-4  0.213
2006 Papandreou MA, Efthimiopoulos S, Cordo-Patis P, Klimis-Zacas D, Margarity M, La-Mari FN. Inhibitory activity on amyloid-β protein aggregation and antioxidant properties of blueberry extract Review of Clinical Pharmacology and Pharmacokinetics, International Edition. 20: 105-107.  0.2
2020 Gourgouli K, Gourgouli I, Tsaousis G, Spai S, Niskopoulou M, Efthimiopoulos S, Lamnissou K. Investigation of genetic base in the treatment of age-related macular degeneration. International Ophthalmology. PMID 31916060 DOI: 10.1007/S10792-019-01274-7  0.192
2023 Paschou M, Liaropoulou D, Kalaitzaki V, Efthimiopoulos S, Papazafiri P. Knockdown of Amyloid Precursor Protein Increases Ion Channel Expression and Alters Ca Signaling Pathways. International Journal of Molecular Sciences. 24. PMID 36768625 DOI: 10.3390/ijms24032302  0.176
2007 Papandreou M, Kanakis C, Polissiou M, Efthimiopoulos S, Cordopatis P, Margarity M, Lamari F. Investigation of in vitro activities of Crocus sativus styles extract relevant to Alzheimer's disease Planta Medica. 73. DOI: 10.1055/S-2007-987288  0.131
2002 Gonos ES, Agrafiotis D, Dontas AS, Efthimiopoulos S, Galaris D, Karamanos NK, Kletsas D, Kolettas E, Panayotou G, Pratsinis H, Sekeri-Pataryas KE, Simoes D, Sourlingas TG, Stathakos D, Stratigos AJ, et al. Ageing research in Greece. Experimental Gerontology. 37: 735-47. PMID 12175474 DOI: 10.1016/S0531-5565(02)00017-7  0.098
2016 Thysiadis S, Mpousis S, Avramidis N, Katsamakas S, Balomenos A, Remelli R, Efthimiopoulos S, Sarli V. Discovery of novel phenoxazinone derivatives as DKK1/LRP6 interaction inhibitors: Synthesis, biological evaluation and structure-activity relationships Bioorganic and Medicinal Chemistry. 24: 1014-1022. DOI: 10.1016/j.bmc.2016.01.025  0.067
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