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Robert P. Bowser, PhD, Yale University - Publications

Pathology University of Pittsburgh, Pittsburgh, PA, United States 
molecular and cellular basis of neurodegenerative diseases

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lorenzini I, Alsop E, Levy J, Gittings LM, Lall D, Rabichow BE, Moore S, Pevey R, Bustos LM, Burciu C, Bhatia D, Singer M, Saul J, McQuade A, Tzioras M, ... ... Bowser R, et al. Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features. Frontiers in Cellular Neuroscience. 17: 1179796. PMID 37346371 DOI: 10.3389/fncel.2023.1179796  0.322
2021 Lehmkuhl EM, Loganathan S, Alsop E, Blythe AD, Kovalik T, Mortimore NP, Barrameda D, Kueth C, Eck RJ, Siddegowda BB, Joardar A, Ball H, Macias ME, Bowser R, Van Keuren-Jensen K, et al. TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6. Acta Neuropathologica Communications. 9: 52. PMID 33762006 DOI: 10.1186/s40478-021-01148-z  0.302
2020 Saul J, Hutchins E, Reiman R, Saul M, Ostrow LW, Harris BT, Van Keuren-Jensen K, Bowser R, Bakkar N. Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 8: 92. PMID 32586411 DOI: 10.1186/S40478-020-00968-9  0.401
2020 Collins M, Li Y, Bowser R. RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases. Acta Neuropathologica Communications. 8: 91. PMID 32586379 DOI: 10.1186/S40478-020-00965-Y  0.411
2020 Huang F, Zhu Y, Hsiao-Nakamoto J, Tang X, Dugas JC, Moscovitch-Lopatin M, Glass JD, Brown RH, Ladha SS, Lacomis D, Harris JM, Scearce-Levie K, Ho C, Bowser R, Berry JD. Longitudinal biomarkers in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology. PMID 32515902 DOI: 10.1002/Acn3.51078  0.575
2020 Vu L, An J, Kovalik T, Gendron T, Petrucelli L, Bowser R. Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31937582 DOI: 10.1136/Jnnp-2019-321916  0.424
2019 Benatar M, Wuu J, Lombardi V, Jeromin A, Bowser R, Andersen PM, Malaspina A. Neurofilaments in pre-symptomatic ALS and the impact of genotype. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 31432691 DOI: 10.1080/21678421.2019.1646769  0.373
2019 Manzo E, Lorenzini I, Barrameda D, O'Conner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Liévens JC, Bowser R, Sattler R, Zarnescu DC. Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS. Elife. 8. PMID 31180318 DOI: 10.7554/Elife.45114  0.338
2019 Manzo E, Lorenzini I, Barrameda D, O'Conner AG, Barrows JM, Starr A, Kovalik T, Rabichow BE, Lehmkuhl EM, Shreiner DD, Joardar A, Liévens J, Bowser R, Sattler R, Zarnescu DC. Author response: Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS Elife. DOI: 10.7554/Elife.45114.037  0.312
2018 Boehringer A, Bowser R. RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases. Advances in Neurobiology. 20: 85-101. PMID 29916017 DOI: 10.1007/978-3-319-89689-2_4  0.323
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Bowser R, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.354
2017 Bakkar N, Kovalik T, Lorenzini I, Spangler S, Lacoste A, Sponaugle K, Ferrante P, Argentinis E, Sattler R, Bowser R. Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 29134320 DOI: 10.1007/S00401-017-1785-8  0.406
2017 Boehringer A, Garcia-Mansfield K, Singh G, Bakkar N, Pirrotte P, Bowser R. ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export. Scientific Reports. 7: 14529. PMID 29109432 DOI: 10.1038/S41598-017-14924-6  0.366
2017 Jeromin A, Bowser R. Biomarkers in Neurodegenerative Diseases. Advances in Neurobiology. 15: 491-528. PMID 28674995 DOI: 10.1007/978-3-319-57193-5_20  0.348
2017 Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, ... ... Bowser R, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28356511 DOI: 10.1126/Scitranslmed.Aai7866  0.56
2016 Vu LT, Bowser R. Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27933485 DOI: 10.1007/S13311-016-0503-X  0.372
2016 Oeckl P, Jardel C, Salachas F, Lamari F, Andersen PM, Bowser R, de Carvalho M, Costa J, van Damme P, Gray E, Grosskreutz J, Hernández-Barral M, Herukka SK, Huss A, Jeromin A, et al. Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 17: 404-413. PMID 27415180 DOI: 10.3109/21678421.2016.1167913  0.366
2016 Li Y, Collins M, An J, Geiser R, Tegeler T, Tsantilas K, Garcia K, Pirrotte P, Bowser R. Immunoprecipitation and Mass Spectrometry Defines an Extensive RBM45 Protein-Protein Interaction Network. Brain Research. PMID 26979993 DOI: 10.1016/J.Brainres.2016.02.047  0.403
2015 Collins MA, An J, Hood BL, Conrads TP, Bowser RP. Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis. Journal of Proteome Research. PMID 26401960 DOI: 10.1021/Acs.Jproteome.5B00804  0.413
2015 Li Y, Collins M, Geiser R, Bakkar N, Riascos D, Bowser R. RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules. Scientific Reports. 5: 14262. PMID 26391765 DOI: 10.1038/Srep14262  0.345
2015 Smith R, Myers K, Ravits J, Bowser R. Amyotrophic lateral sclerosis: Is the spinal fluid pathway involved in seeding and spread? Medical Hypotheses. 85: 576-83. PMID 26220261 DOI: 10.1016/J.Mehy.2015.07.014  0.403
2015 Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Youk A, Talbott EO. Letter to the editor on "Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis". Environmental Pollution (Barking, Essex : 1987). PMID 26002179 DOI: 10.1016/J.Envpol.2015.05.014  0.459
2015 Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1. Molecular and Cellular Biology. 35: 2385-99. PMID 25939382 DOI: 10.1128/MCB.00087-15  0.318
2015 Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Ada Youk, Talbott EO. Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis. Environmental Pollution (Barking, Essex : 1987). 197: 181-6. PMID 25544309 DOI: 10.1016/J.Envpol.2014.12.010  0.513
2014 Coyne AN, Siddegowda BB, Estes PS, Johannesmeyer J, Kovalik T, Daniel SG, Pearson A, Bowser R, Zarnescu DC. Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15962-74. PMID 25429138 DOI: 10.1523/Jneurosci.2526-14.2014  0.399
2014 Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, ... ... Bowser R, et al. Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nature Neuroscience. 17: 664-6. PMID 24686783 DOI: 10.1038/Nn.3688  0.397
2014 Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Youk A, Stickler D, Lackland DT, Talbott EO. Environmental and occupational risk factors for amyotrophic lateral sclerosis: a case-control study. Neuro-Degenerative Diseases. 14: 31-8. PMID 24246552 DOI: 10.1159/000355344  0.506
2013 Pandya RS, Zhu H, Li W, Bowser R, Friedlander RM, Wang X. Therapeutic neuroprotective agents for amyotrophic lateral sclerosis. Cellular and Molecular Life Sciences : Cmls. 70: 4729-45. PMID 23864030 DOI: 10.1007/S00018-013-1415-0  0.387
2013 Quinn C, Macklin EA, Atassi N, Bowser R, Boylan K, Cudkowicz M, Fournier C, Ladha SS, Lacomis D, Berry J. Post-lumbar puncture headache is reduced with use of atraumatic needles in ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 632-4. PMID 23834161 DOI: 10.3109/21678421.2013.808227  0.568
2013 Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL, Rutkove SB, Shaw PJ, Shefner J, Fischbeck KH. Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 19-32. PMID 23678877 DOI: 10.3109/21678421.2013.778554  0.396
2013 Wilson ME, Boumaza I, Bowser R. Measurement of cystatin C functional activity in the cerebrospinal fluid of amyotrophic lateral sclerosis and control subjects. Fluids and Barriers of the Cns. 10: 15. PMID 23497730 DOI: 10.1186/2045-8118-10-15  0.582
2013 Bi F, Huang C, Tong J, Qiu G, Huang B, Wu Q, Li F, Xu Z, Bowser R, Xia XG, Zhou H. Reactive astrocytes secrete lcn2 to promote neuron death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4069-74. PMID 23431168 DOI: 10.1073/Pnas.1218497110  0.352
2013 Winer L, Srinivasan D, Chun S, Lacomis D, Jaffa M, Fagan A, Holtzman DM, Wancewicz E, Bennett CF, Bowser R, Cudkowicz M, Miller TM. SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy. Jama Neurology. 70: 201-7. PMID 23147550 DOI: 10.1001/Jamaneurol.2013.593  0.568
2012 Collins M, Riascos D, Kovalik T, An J, Krupa K, Krupa K, Hood BL, Conrads TP, Renton AE, Traynor BJ, Bowser R. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients. Acta Neuropathologica. 124: 717-32. PMID 22993125 DOI: 10.1007/S00401-012-1045-X  0.458
2012 Levine TD, Bowser R, Hank NC, Gately S, Stephan D, Saperstein DS, Van Keuren-Jensen K. A Pilot Trial of Pioglitazone HCl and Tretinoin in ALS: Cerebrospinal Fluid Biomarkers to Monitor Drug Efficacy and Predict Rate of Disease Progression. Neurology Research International. 2012: 582075. PMID 22830016 DOI: 10.1155/2012/582075  0.333
2012 Malek AM, Barchowsky A, Bowser R, Youk A, Talbott EO. Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies: pesticide exposure as a risk factor for ALS. Environmental Research. 117: 112-9. PMID 22819005 DOI: 10.1016/J.Envres.2012.06.007  0.318
2012 Pandya RS, Mao LL, Zhou EW, Bowser R, Zhu Z, Zhu Y, Wang X. Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy. Central Nervous System Agents in Medicinal Chemistry. 12: 15-27. PMID 22283698 DOI: 10.2174/187152412800229152  0.334
2012 Lawton KA, Cudkowicz ME, Brown MV, Alexander D, Caffrey R, Wulff JE, Bowser R, Lawson R, Jaffa M, Milburn MV, Ryals JA, Berry JD. Biochemical alterations associated with ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 110-8. PMID 22117131 DOI: 10.3109/17482968.2011.619197  0.375
2012 Malek A, Stickler D, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Talbott E, Lackland D. P-075 Epidemiology. 23: 1. DOI: 10.1097/01.Ede.0000417082.53368.56  0.433
2011 Bowser R, Turner MR, Shefner J. Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations. Nature Reviews. Neurology. 7: 631-8. PMID 21989244 DOI: 10.1038/Nrneurol.2011.151  0.377
2011 Ganesalingam J, An J, Shaw CE, Shaw G, Lacomis D, Bowser R. Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS. Journal of Neurochemistry. 117: 528-37. PMID 21418221 DOI: 10.1111/J.1471-4159.2011.07224.X  0.624
2011 Sherman A, Bowser R, Grasso D, Power B, Milligan C, Jaffa M, Cudkowicz M. Proposed BioRepository platform solution for the ALS research community. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 11-6. PMID 21128868 DOI: 10.3109/17482968.2010.539233  0.301
2010 Ranganathan S, Bowser R. p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS. The Open Pathology Journal. 4: 11-22. PMID 21572928 DOI: 10.2174/1874375701004010011  0.587
2010 Liu J, Akhavan A, Lu M, Gruzman A, Lingappa VR, An J, Bowser R. Carbonic anhydrase I is recognized by an SOD1 antibody upon biotinylation of human spinal cord extracts. International Journal of Molecular Sciences. 11: 4051-62. PMID 21152319 DOI: 10.3390/Ijms11104051  0.341
2010 Wilson ME, Boumaza I, Lacomis D, Bowser R. Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis. Plos One. 5: e15133. PMID 21151566 DOI: 10.1371/Journal.Pone.0015133  0.707
2010 Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderweyde T, Vanderwyde T, Citro A, Mehta T, Zaarur N, McKee A, Bowser R, Sherman M, Petrucelli L, Wolozin B. Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. Plos One. 5: e13250. PMID 20948999 DOI: 10.1371/Journal.Pone.0013250  0.394
2010 Ryberg H, An J, Darko S, Lustgarten JL, Jaffa M, Gopalakrishnan V, Lacomis D, Cudkowicz M, Bowser R. Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics. Muscle & Nerve. 42: 104-11. PMID 20583124 DOI: 10.1002/Mus.21683  0.61
2010 Caltagarone J, Hamilton RL, Murdoch G, Jing Z, DeFranco DB, Bowser R. Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi. Journal of Neuropathology and Experimental Neurology. 69: 356-71. PMID 20448481 DOI: 10.1097/Nen.0B013E3181D53D98  0.365
2010 Zhou H, Huang C, Chen H, Wang D, Landel CP, Xia PY, Bowser R, Liu YJ, Xia XG. Transgenic rat model of neurodegeneration caused by mutation in the TDP gene. Plos Genetics. 6: e1000887. PMID 20361056 DOI: 10.1371/Journal.Pgen.1000887  0.347
2010 Ganesalingam J, Lacomis D, Lustgarten J, Shaw C, Bowser R, An J. PATH45 Cytoskeletal and inflammatory protein biomarkers for amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.13  0.595
2009 Bowser R, Lacomis D. Applying proteomics to the diagnosis and treatment of ALS and related diseases. Muscle & Nerve. 40: 753-62. PMID 19670321 DOI: 10.1002/Mus.21488  0.628
2009 Henkel JS, Beers DR, Wen S, Bowser R, Appel SH. Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS. Neurology. 72: 1614-6. PMID 19414730 DOI: 10.1212/Wnl.0B013E3181A41228  0.344
2009 Jing Z, Caltagarone J, Bowser R. Altered subcellular distribution of c-Abl in Alzheimer's disease. Journal of Alzheimer's Disease. 17: 409-422. PMID 19363261 DOI: 10.3233/Jad-2009-1062  0.32
2008 Bonneh-Barkay D, Bissel SJ, Wang G, Fish KN, Nicholl GC, Darko SW, Medina-Flores R, Murphey-Corb M, Rajakumar PA, Nyaundi J, Mellors JW, Bowser R, Wiley CA. YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. The American Journal of Pathology. 173: 130-43. PMID 18556781 DOI: 10.2353/Ajpath.2008.080045  0.521
2008 Ryberg H, Bowser R. Protein biomarkers for amyotrophic lateral sclerosis. Expert Review of Proteomics. 5: 249-262. PMID 18466055 DOI: 10.1586/14789450.5.2.249  0.395
2007 Ranganathan S, Nicholl GC, Henry S, Lutka F, Sathanoori R, Lacomis D, Bowser R. Comparative proteomic profiling of cerebrospinal fluid between living and post mortem ALS and control subjects. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 8: 373-9. PMID 17852009 DOI: 10.1080/17482960701549681  0.71
2007 Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, Halperin RF, Stamper C, Jensen KR, Letizia D, Hesterlee SE, Pestronk A, Levine T, Bertorini T, Graves MC, ... ... Bowser R, et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. The New England Journal of Medicine. 357: 775-88. PMID 17671248 DOI: 10.1056/Nejmoa070174  0.351
2007 Gruzman A, Wood WL, Alpert E, Prasad MD, Miller RG, Rothstein JD, Bowser R, Hamilton R, Wood TD, Cleveland DW, Lingappa VR, Liu J. Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12524-9. PMID 17636119 DOI: 10.1073/Pnas.0705044104  0.402
2007 Caltagarone J, Jing Z, Bowser R. Focal adhesions regulate Aβ signaling and cell death in Alzheimer's disease Biochimica Et Biophysica Acta. 1772: 438-445. PMID 17215111 DOI: 10.1016/J.Bbadis.2006.11.007  0.364
2007 Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochemical Research. 32: 639-44. PMID 17006760 DOI: 10.1007/S11064-006-9146-3  0.381
2007 Kolarcik CL, Darko SW, Bowser R. Protein biomarkers of amyotrophic lateral sclerosis: mass spectrometry-based characterization of transthyretin Journal of Neuropathology and Experimental Neurology. 66: 425. DOI: 10.1097/01.Jnen.0000268832.00285.25  0.326
2007 Kolarcik CL, Darko SW, Bowser R. Protein biomarkers of amyotrophic lateral sclerosis: mass spectrometry‐based characterization of transthyretin The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A25-B  0.338
2006 Ranganathan S, Polshyna A, Nicholl G, Lyons-Weiler J, Bowser R. Assessment of Protein Stability in Cerebrospinal Fluid Using Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Protein Profiling. Clinical Proteomics. 2: 91-101. PMID 20200596 DOI: 10.1385/Cp:2:1:91  0.534
2006 Kolarcik C, Bowser R. Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease Molecular Diagnosis and Therapy. 10: 281-292. PMID 17022691 DOI: 10.1007/Bf03256203  0.429
2006 Chalovich EM, Zhu JH, Caltagarone J, Bowser R, Chu CT. Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells. The Journal of Biological Chemistry. 281: 17870-81. PMID 16621793 DOI: 10.1074/Jbc.M602632200  0.38
2005 Bowser R, Shyjan A. Biomarker World Congress 2005. Personalized Medicine. 2: 209-212. PMID 29793266 DOI: 10.2217/17410541.2.3.209  0.301
2005 Ranganathan S, Williams E, Ganchev P, Gopalakrishnan V, Lacomis D, Urbinelli L, Newhall K, Cudkowicz ME, Brown RH, Bowser R. Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis. Journal of Neurochemistry. 95: 1461-71. PMID 16313519 DOI: 10.1111/J.1471-4159.2005.03478.X  0.708
2005 Yu X, Caltagarone J, Smith MA, Bowser R. DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells. Journal of Alzheimer's Disease : Jad. 8: 7-21. PMID 16155345 DOI: 10.3233/Jad-2005-8102  0.356
2004 Strachan GD, Morgan KL, Otis LL, Caltagarone J, Gittis A, Bowser R, Jordan-Sciutto KL. Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein. Biochemistry. 43: 12113-22. PMID 15379550 DOI: 10.1021/Bi0494166  0.665
2004 Hamilton RL, Bowser R. Alzheimer disease pathology in amyotrophic lateral sclerosis. Acta Neuropathologica. 107: 515-22. PMID 15024584 DOI: 10.1007/S00401-004-0843-1  0.381
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. Journal of Neuroscience Research. 75: 698-703. PMID 14991845 DOI: 10.1002/Jnr.20028  0.378
2004 Wilson C, Henry S, Smith MA, Bowser R. The p53 homologue p73 accumulates in the nucleus and localizes to neurites and neurofibrillary tangles in Alzheimer disease brain. Neuropathology and Applied Neurobiology. 30: 19-29. PMID 14720173 DOI: 10.1046/J.0305-1846.2003.00496.X  0.371
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk J, Shah S, Atwood CS, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80133-7  0.323
2003 Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B. SEPT5_v2 is a parkin-binding protein. Brain Research. Molecular Brain Research. 117: 179-89. PMID 14559152 DOI: 10.1016/S0169-328X(03)00318-8  0.325
2003 Jahroudi N, Schmaier A, Srikanth S, Mahdi F, Lutka FA, Bowser R. Von Willebrand factor promoter targets the expression of amyloid beta protein precursor to brain vascular endothelial cells of transgenic mice. Journal of Alzheimer's Disease : Jad. 5: 149-58. PMID 12719632 DOI: 10.3233/Jad-2003-5209  0.307
2003 Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathologica. 105: 524-8. PMID 12677454 DOI: 10.1007/S00401-003-0684-3  0.346
2003 Rhodes J, Lutka FA, Jordan-Sciutto KL, Bowser R. Altered expression and distribution of FAC1 during NGF-induced neurite outgrowth of PC12 cells. Neuroreport. 14: 449-52. PMID 12634501 DOI: 10.1097/00001756-200303030-00030  0.611
2003 Ranganathan S, Bowser R. Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis. The American Journal of Pathology. 162: 823-35. PMID 12598317 DOI: 10.1016/S0002-9440(10)63879-5  0.606
2002 Ranganathan S, Bowser R. The 12th International Symposium on ALS/MND: scientific advancements in amyotrophic lateral sclerosis. November 18-20, 2001, Oakland, Calif. Brain Pathology (Zurich, Switzerland). 12: 511-4. PMID 12408238 DOI: 10.1111/J.1750-3639.2002.Tb00469.X  0.554
2002 Bowser R, Smith MA. Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. Journal of Alzheimer's Disease : Jad. 4: 249-54. PMID 12226545 DOI: 10.3233/Jad-2002-4316  0.391
2002 Jordan-Sciutto KL, Malaiyandi LM, Bowser R. Altered distribution of cell cycle transcriptional regulators during Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 61: 358-67. PMID 11939591 DOI: 10.1093/Jnen/61.4.358  0.669
2001 Ranganathan S, Scudiere S, Bowser R. Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis. Journal of Alzheimer's Disease : Jad. 3: 377-385. PMID 12214040 DOI: 10.3233/Jad-2001-3403  0.649
2001 Counts SE, Perez SE, Kahl U, Bartfai T, Bowser RP, Deecher DC, Mash DC, Crawley JN, Mufson EJ. Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease. Cns Drug Reviews. 7: 445-70. PMID 11830760 DOI: 10.1111/J.1527-3458.2001.Tb00210.X  0.344
2001 Jordan-Sciutto K, Rhodes J, Bowser R. Altered subcellular distribution of transcriptional regulators in response to Aβ peptide and during Alzheimer's disease Mechanisms of Ageing and Development. 123: 11-20. PMID 11640947 DOI: 10.1016/S0047-6374(01)00334-7  0.656
2001 Walker MP, Schlaberg R, Hays AP, Bowser R, Lipkin WI. Absence of echovirus sequences in brain and spinal cord of amyotrophic lateral sclerosis patients Annals of Neurology. 49: 249-253. DOI: 10.1002/1531-8249(20010201)49:2<249::Aid-Ana46>3.0.Co;2-3  0.321
2000 Jordan-Sciutto KL, Dragich JM, Caltagarone J, Hall DJ, Bowser R. Fetal Alz-50 clone 1 (FAC1) protein interacts with the Myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity. Biochemistry. 39: 3206-15. PMID 10727212 DOI: 10.1021/Bi992211Q  0.759
2000 Bowser RP, Jordan-Sciutto KL, Rhodes JL. Functional role of transcription factors during aβinduced neuronal cell death Neurobiology of Aging. 21: 53. DOI: 10.1016/S0197-4580(00)82916-4  0.62
1999 Jordan-Sciutto KL, Morgan K, Bowser R. Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 1: 409-417. PMID 12214116 DOI: 10.3233/Jad-1999-1605  0.646
1999 Jordan-Sciutto KL, Dragich JM, Rhodes JL, Bowser R. Fetal Alz-50 clone 1, a novel zinc finger protein, binds a specific DNA sequence and acts as a transcriptional regulator. The Journal of Biological Chemistry. 274: 35262-8. PMID 10575013 DOI: 10.1074/Jbc.274.49.35262  0.755
1999 Jordan-Sciutto KL, Dragich JM, Bowser R. DNA binding activity of the fetal Alz-50 clone 1 (FAC1) protein is enhanced by phosphorylation. Biochemical and Biophysical Research Communications. 260: 785-9. PMID 10403843 DOI: 10.1006/Bbrc.1999.0986  0.762
1999 Beites CL, Xie H, Bowser R, Trimble WS. The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nature Neuroscience. 2: 434-9. PMID 10321247 DOI: 10.1038/8100  0.328
1998 Mufson EJ, Kahl U, Bowser R, Mash DC, Kordower JH, Deecher DC. Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential. Annals of the New York Academy of Sciences. 863: 291-304. PMID 9928179 DOI: 10.1111/J.1749-6632.1998.Tb10703.X  0.347
1998 Bowser R, Reilly S. Expression of FAC1 in activated microglia during Alzheimer's disease Neuroscience Letters. 253: 163-166. PMID 9792236 DOI: 10.1016/S0304-3940(98)00636-3  0.389
1998 Caltagarone J, Rhodes J, Honer WG, Bowser R. Localization of a novel septin protein, hCDCrel-1, in neurons of human brain. Neuroreport. 9: 2907-2912. PMID 9760144 DOI: 10.1097/00001756-199808240-00042  0.326
1998 Jordan-Sciutto K, Bowser R. Alzheimer's disease and brain development: common molecular pathways Frontiers in Bioscience : a Journal and Virtual Library. 3: d100-112. PMID 9422711  0.631
1997 Mu X, Springer JE, Bowser R. FAC1 Expression and Localization in Motor Neurons of Developing, Adult, and Amyotrophic Lateral Sclerosis Spinal Cord Experimental Neurology. 146: 17-24. PMID 9225734 DOI: 10.1006/Exnr.1997.6508  0.343
1997 Bowser R, Kordower JH, Mufson EJ. A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 7: 723-30. PMID 9161723 DOI: 10.1111/J.1750-3639.1997.Tb01058.X  0.313
1997 Jicha GA, Bowser R, Kazam IG, Davies P. Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. Journal of Neuroscience Research. 48: 128-32. PMID 9130141 DOI: 10.1002/(Sici)1097-4547(19970415)48:2<128::Aid-Jnr5>3.0.Co;2-E  0.585
1996 Zhu P, Bowser R. Identification and analysis of the complete cDNA sequence for the human FAC1 gene. Biochimica Et Biophysica Acta. 1309: 5-8. PMID 8950167 DOI: 10.1016/S0167-4781(96)00127-3  0.323
1996 Schoonover S, Davies P, Bowser R. Immunolocalization and redistribution of the FAC1 protein in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology. 55: 444-55. PMID 8786404 DOI: 10.1097/00005072-199604000-00007  0.486
1996 Ksiezak-Reding H, Leibowitz RL, Bowser R, Davies P. Binding of Alz 50 depends on Phe8 in tau synthetic peptides and varies between native and denatured tau proteins. Brain Research. 697: 63-75. PMID 8593596 DOI: 10.1016/0006-8993(95)00785-O  0.38
1996 Wiley CA, Baldwin M, Dorsey R, Bowser R, Achim CL. Changes In Gene Expression During Hiv Encephalitis And AlzheimerʼS Disease Journal of Neuropathology and Experimental Neurology. 55: 659. DOI: 10.1097/00005072-199605000-00222  0.417
1995 Govindan B, Bowser R, Novick P. The role of Myo2, a yeast class V myosin, in vesicular transport. The Journal of Cell Biology. 128: 1055-68. PMID 7896871 DOI: 10.1083/Jcb.128.6.1055  0.304
1995 Bowser R, Giambrone A, Davies P. FAC1, a novel gene identified with the monoclonal antibody Alz50, is developmentally regulated in human brain. Developmental Neuroscience. 17: 20-37. PMID 7621746 DOI: 10.1159/000111270  0.402
1995 Bowser R, Giambrone A, Davies P. FAC1, a Novel Gene Identified with the Monoclonal Antibody Alz50, Is Developmentally Regulated in Human Brain (Part 2 of 2) Developmental Neuroscience. 17: 30-37. DOI: 10.1159/000315743  0.359
1992 Potenza M, Bowser R, Müller H, Novick P. SEC6 encodes an 85 kDa soluble protein required for exocytosis in yeast. Yeast (Chichester, England). 8: 549-58. PMID 1523887 DOI: 10.1002/Yea.320080706  0.312
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