Christian Winkler - Publications

Neurology University of Freiburg, Germany, Freiburg im Breisgau, Baden-Württemberg, Germany 
Cell transplantation

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Winkler C, Reis J, Hoffmann N, Gellner AK, Münkel C, Curado MR, Furlanetti L, Garcia J, Döbrössy MD, Fritsch B. Anodal Transcranial Direct Current Stimulation Enhances Survival and Integration of Dopaminergic Cell Transplants in a Rat Parkinson Model. Eneuro. 4. PMID 28966974 DOI: 10.1523/ENEURO.0063-17.2017  0.603
2015 Furlanetti LL, Cordeiro JG, Cordeiro KK, García JA, Winkler C, Lepski GA, Coenen VA, Nikkhah G, Döbrössy MD. Continuous High-Frequency Stimulation of the Subthalamic Nucleus Improves Cell Survival and Functional Recovery Following Dopaminergic Cell Transplantation in Rodents. Neurorehabilitation and Neural Repair. PMID 25857428 DOI: 10.1177/1545968315581419  0.76
2014 Cordeiro KK, Cordeiro JG, Furlanetti LL, Garcia Salazar JA, Tenório SB, Winkler C, Döbrössy MD, Nikkhah G. Subthalamic nucleus lesion improves cell survival and functional recovery following dopaminergic cell transplantation in parkinsonian rats. The European Journal of Neuroscience. 39: 1474-84. PMID 24628951 DOI: 10.1111/Ejn.12541  0.67
2014 Piroth T, Pauly MC, Schneider C, Wittmer A, Möllers S, Döbrössy M, Winkler C, Nikkhah G. Transplantation of human fetal tissue for neurodegenerative diseases: validation of a new protocol for microbiological analysis and bacterial decontamination. Cell Transplantation. 23: 995-1007. PMID 23635602 DOI: 10.3727/096368913X666449  0.558
2013 Pauly MC, Döbrössy MD, Nikkhah G, Winkler C, Piroth T. Organization of the human fetal subpallium. Frontiers in Neuroanatomy. 7: 54. PMID 24474906 DOI: 10.3389/Fnana.2013.00054  0.563
2013 Piroth T, Pauly M, Döbrössy M, Nikkhah G, Winkler C. Regional characterization of fetal progenitor cells for cell transplantation in neurodegenerative diseases Basal Ganglia. 3: 55. DOI: 10.1016/J.Baga.2013.01.043  0.526
2013 Furlanetti L, Cordeiro K, Cordeiro J, Garcia J, Winkler C, Döbrössy M, Nikkhah G. The effect of subthalamic nucleus inhibition in the survival of dopaminergic grafts in a rat model of Parkinson's disease Basal Ganglia. 3: 46. DOI: 10.1016/J.Baga.2013.01.020  0.733
2013 Langer F, Garcia J, Carlsson T, Nikkhah G, Winkler C. Extrastriatal dopamine degeneration and dopaminergic grafts for the development of L-DOPA-induced dyskinesia Basal Ganglia. 3: 45-46. DOI: 10.1016/J.Baga.2013.01.019  0.795
2012 Lane EL, Winkler C. L-DOPA- and graft-induced dyskinesia following transplantation. Progress in Brain Research. 200: 143-68. PMID 23195418 DOI: 10.1016/B978-0-444-59575-1.00007-7  0.757
2012 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Impact of dopamine versus serotonin cell transplantation for the development of graft-induced dyskinesia in a rat Parkinson model. Brain Research. 1470: 119-29. PMID 22759908 DOI: 10.1016/J.Brainres.2012.06.029  0.777
2012 Shin E, Garcia J, Winkler C, Björklund A, Carta M. Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease. Neurobiology of Disease. 47: 393-406. PMID 22579773 DOI: 10.1016/J.Nbd.2012.03.038  0.747
2012 Kaindlstorfer C, García J, Winkler C, Wenning GK, Nikkhah G, Döbrössy MD. Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy. Journal of Neuroscience Research. 90: 1284-95. PMID 22488729 DOI: 10.1002/Jnr.23021  0.627
2011 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation. Experimental Neurology. 232: 270-9. PMID 21946270 DOI: 10.1016/J.Expneurol.2011.09.017  0.777
2011 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Impact of dopamine to serotonin cell ratio in transplants on behavioral recovery and L-DOPA-induced dyskinesia. Neurobiology of Disease. 43: 576-87. PMID 21600983 DOI: 10.1016/J.Nbd.2011.05.004  0.758
2011 Capetian P, Döbrössy M, Winkler C, Prinz M, Nikkhah G. To be or not to be accepted: the role of immunogenicity of neural stem cells following transplantation into the brain in animal and human studies. Seminars in Immunopathology. 33: 619-26. PMID 21533909 DOI: 10.1007/s00281-011-0272-x  0.599
2010 Lane EL, Björklund A, Dunnett SB, Winkler C. Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia. Progress in Brain Research. 184: 295-309. PMID 20887881 DOI: 10.1016/S0079-6123(10)84015-4  0.767
2009 Carlsson T, Carta M, Muñoz A, Mattsson B, Winkler C, Kirik D, Björklund A. Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration. Brain : a Journal of Neurology. 132: 319-35. PMID 19039008 DOI: 10.1093/Brain/Awn305  0.817
2007 Carlsson T, Carta M, Winkler C, Björklund A, Kirik D. Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8011-22. PMID 17652591 DOI: 10.1523/Jneurosci.2079-07.2007  0.813
2007 Breysse N, Carlsson T, Winkler C, Björklund A, Kirik D. The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5849-56. PMID 17537955 DOI: 10.1523/Jneurosci.0626-07.2007  0.815
2007 Timmer M, Cesnulevicius K, Winkler C, Kolb J, Lipokatic-Takacs E, Jungnickel J, Grothe C. Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 459-71. PMID 17234579 DOI: 10.1523/Jneurosci.4493-06.2007  0.383
2006 Winkler C, Georgievska B, Carlsson T, Lacar B, Kirik D. Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats. Neuroscience. 141: 521-31. PMID 16697115 DOI: 10.1016/J.Neuroscience.2006.03.068  0.784
2006 Winkler C, Gil JM, Araújo IM, Riess O, Skripuletz T, von Hörsten S, Petersén A. Normal sensitivity to excitotoxicity in a transgenic Huntington's disease rat. Brain Research Bulletin. 69: 306-10. PMID 16564426 DOI: 10.1016/J.Brainresbull.2006.01.003  0.335
2006 Lane EL, Winkler C, Brundin P, Cenci MA. The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat. Neurobiology of Disease. 22: 334-45. PMID 16406222 DOI: 10.1016/J.Nbd.2005.11.011  0.802
2006 Carlsson T, Winkler C, Lundblad M, Cenci MA, Björklund A, Kirik D. Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiology of Disease. 21: 657-68. PMID 16256359 DOI: 10.1016/J.Nbd.2005.09.008  0.774
2006 Herrmann J, Timmer M, Nikkhah G, Dengler R, Winkler C. L-DOPA-induced dyskinesia in the rat Parkinson model: interhemispheric functional coupling of the two nigrostriatal pathways Aktuelle Neurologie. 33. DOI: 10.1055/S-2006-953139  0.526
2005 Puschban Z, Stefanova N, Petersén A, Winkler C, Brundin P, Poewe W, Wenning GK. Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy. Brain Research Bulletin. 68: 54-8. PMID 16325004 DOI: 10.1016/J.Brainresbull.2005.08.025  0.668
2005 Winkler C, Kirik D, Björklund A. Cell transplantation in Parkinson's disease: how can we make it work? Trends in Neurosciences. 28: 86-92. PMID 15667931 DOI: 10.1016/J.Tins.2004.12.006  0.648
2005 Carlsson T, Winkler C, Burger C, Muzyczka N, Mandel RJ, Cenci A, Björklund A, Kirik D. Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors. Brain : a Journal of Neurology. 128: 559-69. PMID 15659429 DOI: 10.1093/Brain/Awh374  0.794
2005 Winkler C, Carlsson T, Burger C, Muzyczka N, Mandel R, Cenci A, Björklund A, Dengler R, Kirik D. Normalisierung der striatalen Genexpression und Reduktion L-DOPA-induzierter Dyskinesien durch viralen Gentransfer im Tiermodell der Parkinson'schen Erkrankung Aktuelle Neurologie. 32. DOI: 10.1055/S-2005-866631  0.691
2005 Georgievska B, Winkler C, Carlsson T, Lacar B, Kirik D. 941. Delayed GDNF Exposure to Mature Dopaminergic Grafts Impairs Their Ability To Improve Motor Function in Parkinsonian Rats Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.484  0.77
2005 Lane EL, Winkler C, Mela F, Lundblad M, Brundin P, Cenci MA. The importance of graft size in the development of graft-induced dyskinesia [Abstract] Experimental Neurology. DOI: 10.1016/J.Expneurol.2005.02.005  0.755
2004 Georgievska B, Carlsson T, Lacar B, Winkler C, Kirik D. Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor. The European Journal of Neuroscience. 20: 3121-30. PMID 15579166 DOI: 10.1111/J.1460-9568.2004.03770.X  0.757
2004 Grothe C, Timmer M, Scholz T, Winkler C, Nikkhah G, Claus P, Itoh N, Arenas E. Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons. Neurobiology of Disease. 17: 163-70. PMID 15474354 DOI: 10.1016/J.Nbd.2004.07.007  0.638
2004 Timmer M, Müller-Ostermeyer F, Kloth V, Winkler C, Grothe C, Nikkhah G. Enhanced survival, reinnervation, and functional recovery of intrastriatal dopamine grafts co-transplanted with Schwann cells overexpressing high molecular weight FGF-2 isoforms. Experimental Neurology. 187: 118-36. PMID 15081594 DOI: 10.1016/J.Expneurol.2004.01.013  0.526
2004 Winkler C, Carlsson T, Burger C, Muzyczka N, Mandel R, Cenci A, Dengler R, Björklund A, Kirik D. Reversal of L-DOPA-induced dyskinesia by recombinant AAV-mediated gene transfer Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-833029  0.67
2003 Winkler C, Bentlage C, Cenci MA, Nikkhah G, Björklund A. Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model. Neuroscience. 118: 1063-77. PMID 12732251 DOI: 10.1016/S0306-4522(03)00007-1  0.526
2002 Winkler C, Kirik D, Björklund A, Cenci MA. L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiology of Disease. 10: 165-86. PMID 12127155 DOI: 10.1006/Nbdi.2002.0499  0.658
2002 Kirik D, Georgievska B, Burger C, Winkler C, Muzyczka N, Mandel RJ, Bjorklund A. Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 99: 4708-13. PMID 11917105 DOI: 10.1073/Pnas.062047599  0.658
2002 Lundblad M, Andersson M, Winkler C, Kirik D, Wierup N, Cenci MA. Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. The European Journal of Neuroscience. 15: 120-32. PMID 11860512 DOI: 10.1046/J.0953-816X.2001.01843.X  0.624
2001 Kirik D, Winkler C, Björklund A. Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2889-96. PMID 11306640 DOI: 10.1523/Jneurosci.21-08-02889.2001  0.715
2001 Roedter A, Winkler C, Samii M, Walter GF, Brandis A, Nikkhah G. Comparison of unilateral and bilateral intrastriatal 6-hydroxydopamine-induced axon terminal lesions: evidence for interhemispheric functional coupling of the two nigrostriatal pathways. The Journal of Comparative Neurology. 432: 217-29. PMID 11241387 DOI: 10.1002/Cne.1098  0.526
2000 Winkler C, Kirik D, Björklund A, Dunnett SB. Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement. Progress in Brain Research. 127: 233-65. PMID 11142030 DOI: 10.1016/S0079-6123(00)27012-X  0.764
2000 Fricker-Gates RA, Winkler C, Kirik D, Rosenblad C, Carpenter MK, Björklund A. EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum. Experimental Neurology. 165: 237-47. PMID 10993684 DOI: 10.1006/Exnr.2000.7482  0.628
2000 Rödter A, Winkler C, Samii M, Nikkhah G. Complex sensorimotor behavioral changes after terminal striatal 6-OHDA lesion and transplantation of dopaminergic embryonic micrografts. Cell Transplantation. 9: 197-214. PMID 10811393 DOI: 10.1177/096368970000900206  0.526
1999 Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Björklund A. Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5990-6005. PMID 10407037 DOI: 10.1523/Jneurosci.19-14-05990.1999  0.416
1999 Winkler C, Bentlage C, Nikkhah G, Samii M, Björklund A. Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants. Experimental Neurology. 155: 165-86. PMID 10072293 DOI: 10.1006/Exnr.1998.6916  0.526
1998 Olsson M, Bjerregaard K, Winkler C, Gates M, Björklund A, Campbell K. Incorporation of mouse neural progenitors transplanted into the rat embryonic forebrain is developmentally regulated and dependent on regional and adhesive properties. The European Journal of Neuroscience. 10: 71-85. PMID 9753115  0.523
1998 Winkler C, Fricker RA, Gates MA, Olsson M, Hammang JP, Carpenter MK, Björklund A. Incorporation and glial differentiation of mouse EGF-responsive neural progenitor cells after transplantation into the embryonic rat brain. Molecular and Cellular Neurosciences. 11: 99-116. PMID 9647689 DOI: 10.1006/Mcne.1998.0674  0.557
1997 Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP. Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice. Experimental Neurology. 148: 187-204. PMID 9398461 DOI: 10.1006/Exnr.1997.6657  0.458
1997 Björklund A, Rosenblad C, Winkler C, Kirik D. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiology of Disease. 4: 186-200. PMID 9361295 DOI: 10.1006/Nbdi.1997.0151  0.657
1997 Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK. Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease. The Journal of Comparative Neurology. 387: 96-113. PMID 9331174 DOI: 10.1002/(Sici)1096-9861(19971013)387:1<96::Aid-Cne8>3.0.Co;2-I  0.493
1996 Lundberg C, Winkler C, Whittemore SR, Björklund A. Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globus pallidus. Neurobiology of Disease. 3: 33-50. PMID 9173911 DOI: 10.1006/Nbdi.1996.0004  0.67
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