Simon N. Young, PhD - Publications

Affiliations: 
Psychiatry McGill University, Montreal, QC, Canada 
Area:
tryptophan, serotonin, behavior

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 aan het Rot M, Moskowitz DS, Hsu ZY, Young SN. Eating a meal is associated with elevations in agreeableness and reductions in dominance and submissiveness. Physiology & Behavior. 144: 103-9. PMID 25770700 DOI: 10.1016/J.Physbeh.2015.03.014  0.637
2015 aan Het Rot M, Moskowitz DS, Young SN. Impulsive behaviour in interpersonal encounters: associations with quarrelsomeness and agreeableness. British Journal of Psychology (London, England : 1953). 106: 152-61. PMID 24606671 DOI: 10.1111/Bjop.12070  0.631
2014 Booij L, Soucy JP, Young SN, Regoli M, Gravel P, Diksic M, Leyton M, Pihl RO, Benkelfat C. Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study. Journal of Neurochemistry. 131: 634-44. PMID 25041501 DOI: 10.1111/Jnc.12826  0.56
2014 Young SN, Moskowitz DS, aan het Rot M. Possible role of more positive social behaviour in the clinical effect of antidepressant drugs. Journal of Psychiatry & Neuroscience : Jpn. 39: 60-5. PMID 24280182 DOI: 10.1503/Jpn.130165  0.655
2014 Young SN, Regoli M, Leyton M, Pihl RO, Benkelfat C. The effect of acute tryptophan depletion on mood and impulsivity in polydrug ecstasy users. Psychopharmacology. 231: 707-16. PMID 24142202 DOI: 10.1007/S00213-013-3287-2  0.554
2014 Hsu ZY, Moskowitz DS, Young SN. The influence of light administration on interpersonal behavior and affect in people with mild to moderate seasonality. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 48: 92-101. PMID 24044973 DOI: 10.1016/J.Pnpbp.2013.09.004  0.311
2013 Young SN. Appropriate amino acid mixtures for tryptophan depletion and tyrosine/phenylalanine depletion and the safety of long-term amino acid depletion in humans. Psychopharmacology. 229: 377-8. PMID 23942520 DOI: 10.1007/S00213-013-3237-Z  0.342
2013 Cawley EI, Park S, aan het Rot M, Sancton K, Benkelfat C, Young SN, Boivin DB, Leyton M. Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder. Journal of Psychiatry & Neuroscience : Jpn. 38: 388-97. PMID 23735584 DOI: 10.1503/Jpn.120181  0.715
2013 Young SN. The effect of raising and lowering tryptophan levels on human mood and social behaviour. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20110375. PMID 23440461 DOI: 10.1098/Rstb.2011.0375  0.364
2013 Young SN. Acute tryptophan depletion in humans: a review of theoretical, practical and ethical aspects. Journal of Psychiatry & Neuroscience : Jpn. 38: 294-305. PMID 23428157 DOI: 10.1503/Jpn.120209  0.332
2013 Ellenbogen MA, Linnen AM, Santo JB, aan het Rot M, Hodgins S, Young SN. Salivary cortisol and interpersonal functioning: an event-contingent recording study in the offspring of parents with bipolar disorder. Psychoneuroendocrinology. 38: 997-1006. PMID 23131593 DOI: 10.1016/J.Psyneuen.2012.10.005  0.642
2011 Nantel-Vivier A, Pihl RO, Young SN, Parent S, Bélanger SA, Sutton R, Dubois ME, Tremblay RE, Séguin JR. Serotonergic contribution to boys' behavioral regulation. Plos One. 6: e20304. PMID 21673801 DOI: 10.1371/Journal.Pone.0020304  0.312
2011 Moskowitz DS, Zuroff DC, Aan het Rot M, Young SN. Tryptophan and interpersonal spin Journal of Research in Personality. 45: 692-696. DOI: 10.1016/J.Jrp.2011.08.002  0.644
2010 aan het Rot M, Coupland N, Boivin DB, Benkelfat C, Young SN. Recognizing emotions in faces: effects of acute tryptophan depletion and bright light. Journal of Psychopharmacology (Oxford, England). 24: 1447-54. PMID 19939873 DOI: 10.1177/0269881109348169  0.633
2009 Linnen AM, aan het Rot M, Ellenbogen MA, Young SN. Interpersonal functioning in adolescent offspring of parents with bipolar disorder. Journal of Affective Disorders. 114: 122-30. PMID 18692905 DOI: 10.1016/J.Jad.2008.06.016  0.642
2008 Barrett SP, Pihl RO, Benkelfat C, Brunelle C, Young SN, Leyton M. The role of dopamine in alcohol self-administration in humans: individual differences. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 439-47. PMID 18367384 DOI: 10.1016/J.Euroneuro.2008.01.008  0.516
2008 aan het Rot M, Russell JJ, Moskowitz DS, Young SN. Alcohol in a social context: findings from event-contingent recording studies of everyday social interactions. Alcoholism, Clinical and Experimental Research. 32: 459-71. PMID 18215215 DOI: 10.1111/J.1530-0277.2007.00590.X  0.629
2008 Newhouse PA, Dumas J, Hancur-Bucci C, Naylor M, Sites CK, Benkelfat C, Young SN. Estrogen administration negatively alters mood following monoaminergic depletion and psychosocial stress in postmenopausal women. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1514-27. PMID 17700646 DOI: 10.1038/Sj.Npp.1301530  0.331
2008 aan het Rot M, Benkelfat C, Boivin DB, Young SN. Bright light exposure during acute tryptophan depletion prevents a lowering of mood in mildly seasonal women. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 14-23. PMID 17582745 DOI: 10.1016/J.Euroneuro.2007.05.003  0.657
2008 aan het Rot M, Moskowitz DS, Young SN. Exposure to bright light is associated with positive social interaction and good mood over short time periods: A naturalistic study in mildly seasonal people. Journal of Psychiatric Research. 42: 311-9. PMID 17275841 DOI: 10.1016/j.jpsychires.2006.11.010  0.615
2007 Leyton M, aan het Rot M, Booij L, Baker GB, Young SN, Benkelfat C. Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion. Journal of Psychiatry & Neuroscience : Jpn. 32: 129-36. PMID 17353942  0.688
2007 Young SN, aan het Rot M, Pinard G, Moskowitz DS. The effect of tryptophan on quarrelsomeness, agreeableness, and mood in everyday life International Congress Series. 1304: 133-143. DOI: 10.1016/j.ics.2007.07.037  0.583
2006 Sakai Y, Nishikawa M, Leyton M, Benkelfat C, Young SN, Diksic M. Cortical trapping of alpha-[(11)C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males. Neuroimage. 33: 815-24. PMID 16996279 DOI: 10.1016/J.Neuroimage.2006.08.004  0.563
2006 aan het Rot M, Moskowitz DS, Pinard G, Young SN. Social behaviour and mood in everyday life: the effects of tryptophan in quarrelsome individuals. Journal of Psychiatry & Neuroscience : Jpn. 31: 253-62. PMID 16862243  0.639
2006 Casey KF, Benkelfat C, Young SN, Leyton M. Lack of effect of acute dopamine precursor depletion in nicotine-dependent smokers. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 512-20. PMID 16545549 DOI: 10.1016/J.Euroneuro.2006.02.002  0.506
2006 Steiger H, Gauvin L, Joober R, Israel M, Ng Ying Kin NM, Bruce KR, Richardson J, Young SN, Hakim J. Intrafamilial correspondences on platelet [3H-]paroxetine-binding indices in bulimic probands and their unaffected first-degree relatives. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1785-92. PMID 16407896 DOI: 10.1038/Sj.Npp.1301011  0.35
2006 Berney A, Sookman D, Leyton M, Young SN, Benkelfat C. Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients. Biological Psychiatry. 59: 853-7. PMID 16213470 DOI: 10.1016/J.Biopsych.2005.08.023  0.549
2005 Nishikawa M, Kumakura Y, Young SN, Fiset P, Vogelzangs N, Leyton M, Benkelfat C, Diksic M. Increasing blood oxygen increases an index of 5-HT synthesis in human brain as measured using alpha-[(11)C]methyl-L-tryptophan and positron emission tomography. Neurochemistry International. 47: 556-64. PMID 16157418 DOI: 10.1016/J.Neuint.2005.07.006  0.549
2005 Bruce KR, Steiger H, Joober R, Ng Ying Kin NM, Israel M, Young SN. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 137: 40-4. PMID 15999344 DOI: 10.1002/Ajmg.B.30205  0.323
2005 Steiger H, Joober R, Israël M, Young SN, Ng Ying Kin NM, Gauvin L, Bruce KR, Joncas J, Torkaman-Zehi A. The 5HTTLPR polymorphism, psychopathologic symptoms, and platelet [3H-] paroxetine binding in bulimic syndromes. The International Journal of Eating Disorders. 37: 57-60. PMID 15690467 DOI: 10.1002/Eat.20073  0.323
2005 Diksic M, Sakai Y, Nishikawa M, Leyton M, Benkelfat C, Young SN. Serotonin synthesis is lower in the cortical areas of female than male healthy participants as measured with α-[11C]methyl-L-tryptophan positron emission tomography Journal of Cerebral Blood Flow & Metabolism. 25: S344-S344. DOI: 10.1038/Sj.Jcbfm.9591524.0344  0.551
2005 Young SN, Moskowitz DS. Serotonin and affiliative behavior Behavioral and Brain Sciences. 28: 367-368. DOI: 10.1017/S0140525X05390066  0.3
2004 Steiger H, Gauvin L, Israël M, Kin NM, Young SN, Roussin J. Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders. The Journal of Clinical Psychiatry. 65: 830-7. PMID 15291661 DOI: 10.4088/Jcp.V65N0615  0.344
2004 Bruce KR, Steiger H, Koerner NM, Israel M, Young SN. Bulimia nervosa with co-morbid avoidant personality disorder: behavioural characteristics and serotonergic function. Psychological Medicine. 34: 113-24. PMID 14971632 DOI: 10.1017/S003329170300864X  0.338
2004 Leyton M, Dagher A, Boileau I, Casey K, Baker GB, Diksic M, Gunn R, Young SN, Benkelfat C. Decreasing amphetamine-induced dopamine release by acute phenylalanine/tyrosine depletion: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 427-32. PMID 14583741 DOI: 10.1038/Sj.Npp.1300328  0.541
2003 Moskowitz DS, Pinard G, Zuroff DC, Annable L, Young SN. Tryptophan, serotonin and human social behavior. Advances in Experimental Medicine and Biology. 527: 215-24. PMID 15206735 DOI: 10.1007/978-1-4615-0135-0_25  0.305
2003 Leyton M, Pun VK, Benkelfat C, Young SN. A new method for rapidly and simultaneously decreasing serotonin and catecholamine synthesis in humans. Journal of Psychiatry & Neuroscience : Jpn. 28: 464-7. PMID 14631457  0.517
2003 Steiger H, Israël M, Gauvin L, Ng Ying Kin NM, Young SN. Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa. Psychiatry Research. 120: 219-29. PMID 14561433 DOI: 10.1016/S0165-1781(03)00195-1  0.362
2002 Leyton M, Young SN, Srivastava LK. The 25th annual meeting of the Canadian College of Neuropsychopharmacology. Ottawa, Ontario, Canada, June 9-12, 2002. Journal of Psychiatry & Neuroscience : Jpn. 27: 438-50. PMID 12491577  0.391
2002 Blier P, Seletti B, Gilbert F, Young SN, Benkelfat C. Serotonin 1A receptor activation and hypothermia in humans: lack of evidence for a presynaptic mediation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 301-8. PMID 12093604 DOI: 10.1016/S0893-133X(02)00318-4  0.332
2002 Young SN, Leyton M. The role of serotonin in human mood and social interaction. Insight from altered tryptophan levels. Pharmacology, Biochemistry, and Behavior. 71: 857-65. PMID 11888576 DOI: 10.1016/S0091-3057(01)00670-0  0.616
2002 Diksic M, Okazawa S, Nishizawa S, Leyton M, Young S. A decrease in blood tryptophan concentration produces regionally specific changes in brain serotonin synthesis in men and women: A PET study with alpha-[11C]methyl-L-tryptophan European Neuropsychopharmacology. 12: 403-404. DOI: 10.1016/S0924-977X(02)80688-5  0.537
2002 Benkelfat C, Rosa P, Leyton M, Young S, Mzengeza S, Diksic M. In-vivo measurement of 5HT synthesis capacity in the human brain, using the PET/11 C-αmethyltryptophan method: Clinical applications European Neuropsychopharmacology. 12: 137-138. DOI: 10.1016/S0924-977X(02)80082-7  0.546
2001 Srivastava LK, Leyton M, Young SN. The 24th Annual Meeting of the Canadian College of Neuropsychopharmacology. Banff, Alberta, Canada, June 17-20, 2001. Journal of Psychiatry & Neuroscience : Jpn. 26: 375-84. PMID 11762205  0.391
2001 Diksic M, Young SN. Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan. Journal of Neurochemistry. 78: 1185-200. PMID 11579128 DOI: 10.1046/J.1471-4159.2001.00536.X  0.353
2001 Steiger H, Gauvin L, Israël M, Koerner N, Ng Ying Kin NM, Paris J, Young SN. Association of serotonin and cortisol indices with childhood abuse in bulimia nervosa. Archives of General Psychiatry. 58: 837-43. PMID 11545666 DOI: 10.1001/Archpsyc.58.9.837  0.327
2001 Steiger H, Koerner N, Engelberg MJ, Israël M, Ng Ying Kin NM, Young SN. Self-destructiveness and serotonin function in bulimia nervosa. Psychiatry Research. 103: 15-26. PMID 11472787 DOI: 10.1016/S0165-1781(01)00264-5  0.321
2001 Moskowitz DS, Pinard G, Zuroff DC, Annable L, Young SN. The effect of tryptophan on social interaction in everyday life: a placebo-controlled study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 277-89. PMID 11425511 DOI: 10.1016/S0893-133X(01)00219-6  0.345
2001 Leyton M, Okazawa H, Diksic M, Paris J, Rosa P, Mzengeza S, Young SN, Blier P, Benkelfat C. Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. The American Journal of Psychiatry. 158: 775-82. PMID 11329401 DOI: 10.1176/Appi.Ajp.158.5.775  0.564
2001 Steiger H, Young SN, Kin NM, Koerner N, Israel M, Lageix P, Paris J. Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa. Psychological Medicine. 31: 85-95. PMID 11200963 DOI: 10.1017/S003329179900313X  0.34
2000 Leyton M, Ghadirian AM, Young SN, Palmour RM, Blier P, Helmers KF, Benkelfat C. Depressive relapse following acute tryptophan depletion in patients with major depressive disorder. Journal of Psychopharmacology (Oxford, England). 14: 284-7. PMID 11106310 DOI: 10.1177/026988110001400317  0.542
2000 Steiger H, Léonard S, Kin NY, Ladouceur C, Ramdoyal D, Young SN. Childhood abuse and platelet tritiated-paroxetine binding in bulimia nervosa: implications of borderline personality disorder. The Journal of Clinical Psychiatry. 61: 428-35. PMID 10901341 DOI: 10.4088/Jcp.V61N0607  0.32
2000 Shansis FM, Busnello JV, Quevedo J, Forster L, Young S, Izquierdo I, Kapczinski F. Behavioural effects of acute tryptophan depletion in healthy male volunteers. Journal of Psychopharmacology (Oxford, England). 14: 157-63. PMID 10890310 DOI: 10.1177/026988110001400205  0.324
2000 Leyton M, Young SN, Blier P, Baker GB, Pihl RO, Benkelfat C. Acute tyrosine depletion and alcohol ingestion in healthy women. Alcoholism, Clinical and Experimental Research. 24: 459-64. PMID 10798581 DOI: 10.1111/J.1530-0277.2000.Tb02012.X  0.541
2000 Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. Effects on mood of acute phenylalanine/tyrosine depletion in healthy women. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 52-63. PMID 10633491 DOI: 10.1016/S0893-133X(99)00086-X  0.578
1999 Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women. Advances in Experimental Medicine and Biology. 467: 67-71. PMID 10721039 DOI: 10.1007/978-1-4615-4709-9_8  0.555
1999 Young SN, Leyton M, Benkelfat C. Pet studies of serotonin synthesis in the human brain. Advances in Experimental Medicine and Biology. 467: 11-8. PMID 10721033 DOI: 10.1007/978-1-4615-4709-9_2  0.571
1999 Knott VJ, Howson AL, Perugini M, Ravindran AV, Young SN. The effect of acute tryptophan depletion and fenfluramine on quantitative EEG and mood in healthy male subjects. Biological Psychiatry. 46: 229-38. PMID 10418698 DOI: 10.1016/S0006-3223(98)00338-2  0.365
1999 Benkelfat C, Young SN, Okazawa H, Leyton M, Diksic M. The validity of the PET/alpha-[11C]methyl-L-tryptophan method for measuring rates of serotonin synthesis in the human brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 153-7. PMID 10379530 DOI: 10.1016/S0893-133X(98)00140-7  0.566
1999 Ellenbogen MA, Young SN, Dean P, Palmour RM, Benkelfat C. Acute tryptophan depletion in healthy young women with a family history of major affective disorder. Psychological Medicine. 29: 35-46. PMID 10077292 DOI: 10.1017/S0033291798007685  0.339
1999 Steinberg S, Annable L, Young SN, Liyanage N. A placebo-controlled clinical trial of L-tryptophan in premenstrual dysphoria. Biological Psychiatry. 45: 313-20. PMID 10023508 DOI: 10.1016/S0006-3223(98)00005-5  0.311
1998 Palmour RM, Ervin FR, Baker GB, Young SN. An amino acid mixture deficient in phenylalanine and tyrosine reduces cerebrospinal fluid catecholamine metabolites and alcohol consumption in vervet monkeys. Psychopharmacology. 136: 1-7. PMID 9537676 DOI: 10.1007/S002130050532  0.305
1998 Finn PR, Young SN, Pihl RO, Ervin FR. The effects of acute plasma tryptophan manipulation on hostile mood: The influence of trait hostility Aggressive Behavior. 24: 173-185. DOI: 10.1002/(Sici)1098-2337(1998)24:3<173::Aid-Ab2>3.0.Co;2-M  0.352
1997 Helmers KF, Danoff D, Steinert Y, Leyton M, Young SN. Stress and depressed mood in medical students, law students, and graduate students at McGill University. Academic Medicine : Journal of the Association of American Medical Colleges. 72: 708-14. PMID 9282148 DOI: 10.1097/00001888-199708000-00018  0.469
1997 Leyton M, Young SN, Benkelfat C. Relapse of depression after rapid depletion of tryptophan. Lancet. 349: 1840-1. PMID 9269238 DOI: 10.1016/S0140-6736(05)61726-6  0.497
1997 Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P, Diksic M. Differences between males and females in rates of serotonin synthesis in human brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5308-13. PMID 9144233 DOI: 10.1073/Pnas.94.10.5308  0.553
1997 Leyton M, Young SN, Blier P, Ellenbogen MA, Palmour RM, Ghadirian AM, Benkelfat C. The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 294-7. PMID 9094147 DOI: 10.1016/S0893-133X(96)00262-X  0.528
1997 Leyton M, Diksic M, Young S, Okazawa H, Nishizawa S, Paris J, Mzengeza S, Benkelfat C. Brain regional rates of serotonin synthesis in patients with borderline personality disorder: A PET study with α-[11C]methyl-L-tryptophan Biological Psychiatry. 42: 16S. DOI: 10.1016/S0006-3223(97)86918-1  0.537
1996 Ellenbogen MA, Young SN, Dean P, Palmour RM, Benkelfat C. Mood response to acute tryptophan depletion in healthy volunteers: sex differences and temporal stability. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 465-74. PMID 8914119 DOI: 10.1016/S0893-133X(96)00056-5  0.346
1996 Young SN, Pihl RO, Benkelfat C, Palmour R, Ellenbogen M, Lemarquand D. The effect of low brain serotonin on mood and aggression in humans. Influence of baseline mood and genetic factors. Advances in Experimental Medicine and Biology. 398: 45-50. PMID 8906239 DOI: 10.1007/978-1-4613-0381-7_5  0.39
1996 Koszycki D, Zacharko RM, Le Melledo JM, Young SN, Bradwejn J. Effect of acute tryptophan depletion on behavioral, cardiovascular, and hormonal sensitivity to cholecystokinin-tetrapeptide challenge in healthy volunteers. Biological Psychiatry. 40: 648-55. PMID 8886299 DOI: 10.1016/0006-3223(95)00479-3  0.383
1996 Young SN. Behavioral effects of dietary neurotransmitter precursors: basic and clinical aspects. Neuroscience and Biobehavioral Reviews. 20: 313-23. PMID 8811719 DOI: 10.1016/0149-7634(95)00022-4  0.301
1995 Koski KG, Lanoue L, Young SN. Maternal dietary carbohydrate restriction influences the developmental profile of postnatal rat brain indoleamine metabolism. Biology of the Neonate. 67: 122-31. PMID 7539298 DOI: 10.1159/000244153  0.363
1995 Pihl RO, Young SN, Harden P, Plotnick S, Chamberlain B, Ervin FR. Acute effect of altered tryptophan levels and alcohol on aggression in normal human males. Psychopharmacology. 119: 353-60. PMID 7480513 DOI: 10.1007/Bf02245849  0.322
1995 Teff KL, Young SN. The effect of carbohydrate and protein administration on amino acids in the pancreas, brain, intestine, and plasma of the rat The Journal of Nutritional Biochemistry. 6: 564-569. DOI: 10.1016/0955-2863(95)00130-R  0.642
1994 Benkelfat C, Ellenbogen MA, Dean P, Palmour RM, Young SN. Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders. Archives of General Psychiatry. 51: 687-97. PMID 8080345 DOI: 10.1001/Archpsyc.1994.03950090019003  0.345
1993 Koski KG, Lanoue L, Young SN. Restriction of maternal dietary carbohydrate decreases fetal brain indoles and glycogen in rats. The Journal of Nutrition. 123: 42-51. PMID 8421229 DOI: 10.1093/Jn/123.1.42  0.302
1991 Young SN. The 1989 Borden Award Lecture. Some effects of dietary components (amino acids, carbohydrate, folic acid) on brain serotonin synthesis, mood, and behavior. Canadian Journal of Physiology and Pharmacology. 69: 893-903. PMID 1954564 DOI: 10.1139/Y91-136  0.399
1991 Young SN. Acute effects of meals on brain tryptophan and serotonin in humans. Advances in Experimental Medicine and Biology. 294: 417-23. PMID 1722945 DOI: 10.1007/978-1-4684-5952-4_38  0.366
1990 Franklin KB, Abbott FV, English MJ, Jeans ME, Tasker RA, Young SN. Tryptophan-morphine interactions and postoperative pain. Pharmacology, Biochemistry, and Behavior. 35: 157-63. PMID 2315355 DOI: 10.1016/0091-3057(90)90221-3  0.331
1989 Young SN, Ghadirian AM. Folic acid and psychopathology. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 841-63. PMID 2682787 DOI: 10.1016/0278-5846(89)90037-7  0.317
1989 Young SN, Teff KL. Tryptophan availability, 5HT synthesis and 5HT function. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 373-9. PMID 2664890 DOI: 10.1016/0278-5846(89)90126-7  0.655
1989 Teff KL, Young SN, Blundell JE. The effect of protein or carbohydrate breakfasts on subsequent plasma amino acid levels, satiety and nutrient selection in normal males. Pharmacology, Biochemistry, and Behavior. 34: 829-37. PMID 2623036 DOI: 10.1016/0091-3057(89)90282-7  0.638
1989 Young SN, Ervin FR, Pihl RO, Finn P. Biochemical aspects of tryptophan depletion in primates. Psychopharmacology. 98: 508-11. PMID 2505291 DOI: 10.1007/Bf00441950  0.312
1989 Teff KL, Young SN, Marchand L, Botez MI. Acute effect of protein or carbohydrate breakfasts on human cerebrospinal fluid monoamine precursor and metabolite levels. Journal of Neurochemistry. 52: 235-41. PMID 2462018 DOI: 10.1111/J.1471-4159.1989.Tb10922.X  0.64
1988 Boal AS, Young SN, Sutherland M, Ervin FR, Coppinger R. The effect of breakfast on social behavior and brain amine metabolism in vervet monkeys. Pharmacology, Biochemistry, and Behavior. 29: 115-23. PMID 3353416 DOI: 10.1016/0091-3057(88)90283-3  0.312
1988 Young SN, Tourjman SV, Teff KL, Pihl RO, Anderson GH. The effect of lowering plasma tryptophan on food selection in normal males. Pharmacology, Biochemistry, and Behavior. 31: 149-52. PMID 3252245 DOI: 10.1016/0091-3057(88)90326-7  0.634
1988 Teff KL, Young SN. Effects of carbohydrate and protein administration on rat tryptophan and 5-hydroxytryptamine: differential effects on the brain, intestine, pineal, and pancreas. Canadian Journal of Physiology and Pharmacology. 66: 683-8. PMID 3167682 DOI: 10.1139/Y88-108  0.661
1988 Young SN, Pihl RO, Ervin FR. The effect of altered tryptophan levels on mood and behavior in normal human males. Clinical Neuropharmacology. 11: S207-15. PMID 3052819  0.302
1988 Abbott FV, Young SN. Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test. Pharmacology, Biochemistry, and Behavior. 31: 855-60. PMID 2472642 DOI: 10.1016/0091-3057(88)90395-4  0.327
1987 Smith SE, Pihl RO, Young SN, Ervin FR. A test of possible cognitive and environmental influences on the mood lowering effect of tryptophan depletion in normal males. Psychopharmacology. 91: 451-7. PMID 3108925 DOI: 10.1007/Bf00216010  0.39
1987 Anderson GM, Teff KL, Young SN. Serotonin in cisternal cerebrospinal fluid of the rat: measurement and use as an index of functionally active serotonin. Life Sciences. 40: 2253-60. PMID 2438530 DOI: 10.1016/0024-3205(87)90061-0  0.648
1986 Smith SE, Pihl RO, Young SN, Ervin FR. Elevation and reduction of plasma tryptophan and their effects on aggression and perceptual sensitivity in normal males Aggressive Behavior. 12: 393-407. DOI: 10.1002/1098-2337(1986)12:6<393::Aid-Ab2480120602>3.0.Co;2-L  0.391
1985 Young SN, Smith SE, Pihl RO, Ervin FR. Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology. 87: 173-7. PMID 3931142 DOI: 10.1007/Bf00431803  0.359
1982 Gibson CJ, Deikel SM, Young SN, Binik YM. Behavioural and biochemical effects of tryptophan, tyrosine and phenylalanine in mice. Psychopharmacology. 76: 118-21. PMID 6805020 DOI: 10.1007/Bf00435264  0.303
1982 Young SN, Gauthier S, Chouinard G, Anderson GM, Purdy WC. The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels. Journal of Neural Transmission. 53: 83-7. PMID 6801200 DOI: 10.1007/Bf01243522  0.377
1982 Young SN, Anderson GM. Factors influencing melatonin, 5-hydroxytryptophol, 5-hydroxyindoleacetic acid, 5-hydroxytryptamine and tryptophan in rat pineal glands. Neuroendocrinology. 35: 464-8. PMID 6185873 DOI: 10.1159/000123423  0.351
1981 Young SN. Mechanism of decline in rat brain 5-hydroxytryptamine after induction of liver tryptophan pyrrolase by hydrocortisone: roles of tryptophan catabolism and kynurenine synthesis. British Journal of Pharmacology. 74: 695-700. PMID 7296169 DOI: 10.1111/J.1476-5381.1981.Tb10480.X  0.378
1981 Young SN, Gauthier S. Tryptophan availability and the control of 5-hydroxytryptamine and tryptamine synthesis in human CNS. Advances in Experimental Medicine and Biology. 133: 221-30. PMID 6172015 DOI: 10.1007/978-1-4684-3860-4_12  0.367
1981 Young SN, Gauthier S. Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid. Journal of Neurology, Neurosurgery, and Psychiatry. 44: 323-8. PMID 6165809 DOI: 10.1136/Jnnp.44.4.323  0.35
1980 Young SN, Gauthier S, Anderson GM, Purdy WC. Tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human cerebrospinal fluid: interrelationships and the influence of age, sex, epilepsy and anticonvulsant drugs. Journal of Neurology, Neurosurgery, and Psychiatry. 43: 438-45. PMID 6158559 DOI: 10.1136/Jnnp.43.5.438  0.309
1980 Young SN, Anderson GM, Purdy WC. Indoleamine metabolism in rat brain studied through measurements of tryptophan, 5-hydroxyindoleacetic acid, and indoleacetic acid in cerebrospinal fluid. Journal of Neurochemistry. 34: 309-15. PMID 6157779 DOI: 10.1111/J.1471-4159.1980.Tb06598.X  0.376
1979 Botez MI, Young SN, Bachevalier J, Gauthier S. Folate deficiency and decreased brain 5-hydroxytryptamine synthesis in man and rat. Nature. 278: 182-3. PMID 763364 DOI: 10.1038/278182A0  0.371
1979 Young SN, Oravec M. The effect of growth hormone on the metabolism of a tryptophan load in the liver and brain of hypophysectomized rats. Canadian Journal of Biochemistry. 57: 517-22. PMID 38890 DOI: 10.1139/O79-065  0.305
1976 Young SN, Etienne P, Sourkes TL. Relationship between rat brain and cisternal CSF tryptophan concentrations. Journal of Neurology, Neurosurgery, and Psychiatry. 39: 239-43. PMID 945332 DOI: 10.1136/Jnnp.39.3.239  0.306
1976 Etienne P, Young SN, Sourkes TL. Inhibition by albumin of tryptophan uptake by rat brain Nature. 262: 144-145. PMID 934332 DOI: 10.1038/262144A0  0.353
1975 Green AR, Sourkes TL, Young SN. Liver and brain tryptophan metabolism following hydrocortisone administration to rats and gerbils. British Journal of Pharmacology. 53: 287-92. PMID 1148489 DOI: 10.1111/J.1476-5381.1975.Tb07360.X  0.347
1974 Young SN, Garelis E, Lal S, Martin JB, Molina-Negro P, Ethier R, Sourkes TL. Tryptophan and 5-hydroxyindoleacetic acid in human cerebrospinal fluid. Journal of Neurochemistry. 22: 777-9. PMID 4407274 DOI: 10.1111/J.1471-4159.1974.Tb04294.X  0.365
1974 Garelis E, Young SN, Lal S, Sourkes TL. Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies. Brain Research. 79: 1-8. PMID 4279131 DOI: 10.1016/0006-8993(74)90562-9  0.316
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