Kozo Kaibuchi - Publications

Affiliations: 
Nagoya University Graduate School of Medicine, Nagoya-shi, Aichi-ken, Japan 

366 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kannon T, Murashige S, Nishioka T, Amano M, Funahashi Y, Tsuboi D, Yamahashi Y, Nagai T, Kaibuchi K, Yoshimoto J. KANPHOS: Kinase-associated neural phospho-signaling database for data-driven research. Frontiers in Molecular Neuroscience. 17: 1379089. PMID 38628370 DOI: 10.3389/fnmol.2024.1379089  0.304
2022 Hossen E, Funahashi Y, Faruk MO, Ahammad RU, Amano M, Yamada K, Kaibuchi K. Rho-Kinase/ROCK Phosphorylates PSD-93 Downstream of NMDARs to Orchestrate Synaptic Plasticity. International Journal of Molecular Sciences. 24. PMID 36613848 DOI: 10.3390/ijms24010404  0.307
2022 Hanafusa H, Kedashiro S, Gotoh M, Saitoh KH, Inaba H, Nishioka T, Kaibuchi K, Inagaki M, Hisamoto N, Matsumoto K. LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport. Journal of Cell Science. 135. PMID 36254578 DOI: 10.1242/jcs.259999  0.355
2022 Amano M, Kanazawa Y, Kozawa K, Kaibuchi K. Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase. Biomolecules. 12. PMID 35204659 DOI: 10.3390/biom12020159  0.328
2021 Ahammad RU, Nishioka T, Yoshimoto J, Kannon T, Amano M, Funahashi Y, Tsuboi D, Faruk MO, Yamahashi Y, Yamada K, Nagai T, Kaibuchi K. KANPHOS: A Database of Kinase-Associated Neural Protein Phosphorylation in the Brain. Cells. 11. PMID 35011609 DOI: 10.3390/cells11010047  0.319
2021 Ariza A, Funahashi Y, Kozawa S, Omar Faruk M, Nagai T, Amano M, Kaibuchi K. Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK. Journal of Neurochemistry. PMID 33449379 DOI: 10.1111/jnc.15303  0.795
2020 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, ... Kaibuchi K, et al. DSCAM regulates delamination of neurons in the developing midbrain. Science Advances. 6. PMID 32917586 DOI: 10.1126/Sciadv.Aba1693  0.337
2020 Sekiguchi M, Sobue A, Kushima I, Wang C, Arioka Y, Kato H, Kodama A, Kubo H, Ito N, Sawahata M, Hada K, Ikeda R, Shinno M, Mizukoshi C, Tsujimura K, ... ... Kaibuchi K, et al. ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk. Translational Psychiatry. 10: 247. PMID 32699248 DOI: 10.1038/S41398-020-00917-Z  0.393
2020 Chowdhury MIH, Nishioka T, Mishima N, Ohtsuka T, Kaibuchi K, Tsuboi D. Prickle2 and Igsf9b coordinately regulate the cytoarchitecture of the axon initial segment. Cell Structure and Function. PMID 32641624 DOI: 10.1247/Csf.20028  0.307
2020 Ikezu S, Ingraham Dixie KL, Koro L, Watanabe T, Kaibuchi K, Ikezu T. Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models. Acta Neuropathologica Communications. 8: 12. PMID 32019603 DOI: 10.1186/S40478-020-0890-4  0.401
2019 Funahashi Y, Ariza A, Emi R, Xu Y, Shan W, Suzuki K, Kozawa S, Ahammad RU, Wu M, Takano T, Yura Y, Kuroda K, Nagai T, Amano M, Yamada K, ... Kaibuchi K, et al. Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. Cell Reports. 29: 3235-3252.e9. PMID 31801086 DOI: 10.1016/J.Celrep.2019.10.116  0.793
2019 Koike R, Amano M, Kaibuchi K, Ota M. Protein kinases phosphorylate long disordered regions in intrinsically disordered proteins. Protein Science : a Publication of the Protein Society. PMID 31724233 DOI: 10.1002/Pro.3789  0.438
2019 Nishino T, Tamada K, Maeda A, Abe T, Kiyonari H, Funahashi Y, Kaibuchi K, Takumi T, Konishi H. Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain. Molecular Brain. 12: 94. PMID 31718706 DOI: 10.1186/S13041-019-0512-X  0.362
2019 Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, ... ... Kaibuchi K, et al. Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of its Interaction with Actin. Circulation. PMID 31564129 DOI: 10.1161/Circulationaha.119.041019  0.403
2019 Ogino K, Yamada K, Nishioka T, Oda Y, Kaibuchi K, Hirata H. Phosphorylation of gephyrin in zebrafish Mauthner cells governs glycine receptor clustering and behavioral desensitization to sound. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31558619 DOI: 10.1523/Jneurosci.1315-19.2019  0.336
2019 Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, Kimura T, Yoshimatsu S, Kisa F, Karch CM, Miyasaka T, Takashima A, Sahara N, Hisanaga SI, Ikeuchi T, ... Kaibuchi K, et al. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem Cell Reports. PMID 31543469 DOI: 10.1016/J.Stemcr.2019.08.011  0.312
2019 Kimura T, Yamaoka M, Terabayashi T, Kaibuchi K, Ishikawa T, Ishizaki T. GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion. Biological & Pharmaceutical Bulletin. 42: 1532-1537. PMID 31474712 DOI: 10.1248/Bpb.B19-00242  0.361
2019 Hanafusa H, Yagi T, Ikeda H, Hisamoto N, Nishioka T, Kaibuchi K, Shirakabe K, Matsumoto K. LRRK1 phosphorylation of Rab7 at Ser-72 links trafficking of EGFR-containing endosomes to its effector RILP. Journal of Cell Science. PMID 31085713 DOI: 10.1242/Jcs.228809  0.406
2019 Takano T, Funahashi Y, Kaibuchi K. Neuronal Polarity: Positive and Negative Feedback Signals. Frontiers in Cell and Developmental Biology. 7: 69. PMID 31069225 DOI: 10.3389/Fcell.2019.00069  0.313
2019 Nishioka T, Amano M, Funahashi Y, Tsuboi D, Yamahashi Y, Kaibuchi K. In Vivo Identification of Protein Kinase Substrates by Kinase-Oriented Substrate Screening (KIOSS). Current Protocols in Chemical Biology. e60. PMID 30615307 DOI: 10.1002/Cpch.60  0.469
2018 Amano M, Nishioka T, Tsuboi D, Kuroda K, Funahashi Y, Yamahashi Y, Kaibuchi K. Comprehensive analysis of kinase-oriented phospho-signaling pathways. Journal of Biochemistry. PMID 30590682 DOI: 10.1093/Jb/Mvy115  0.433
2018 Zhang X, Nagai T, Ahammad RU, Kuroda K, Nakamuta S, Nakano T, Yukinawa N, Funahashi Y, Yamahashi Y, Amano M, Yoshimoto J, Yamada K, Kaibuchi K. Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons. Neurochemistry International. PMID 30336179 DOI: 10.1016/J.Neuint.2018.10.008  0.371
2018 Bin Saifullah MA, Nagai T, Kuroda K, Wulaer B, Nabeshima T, Kaibuchi K, Yamada K. Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice. Scientific Reports. 8: 14413. PMID 30258218 DOI: 10.1038/S41598-018-32840-1  0.361
2018 Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H. Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. Nature Communications. 9: 433. PMID 29382817 DOI: 10.1038/S41467-018-02821-Z  0.371
2018 Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M. Meis1 coordinates cerebellar granule cell development by regulating Pax6 transcription, BMP signaling and Atoh1 degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29317485 DOI: 10.1523/Jneurosci.1545-17.2017  0.384
2017 Itoh N, Nagai T, Watanabe T, Taki K, Nabeshima T, Kaibuchi K, Yamada K. Valocin-containing protein (VCP) is a novel IQ motif containing GTPase activating protein 1 (IQGAP1) interacting protein. Biochemical and Biophysical Research Communications. PMID 28970065 DOI: 10.1016/J.Bbrc.2017.09.159  0.393
2017 Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M. Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus. Cell Reports. 20: 960-972. PMID 28746879 DOI: 10.1016/J.Celrep.2017.06.089  0.312
2017 Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K. Discovery of long-range inhibitory signaling to ensure single axon formation. Nature Communications. 8: 33. PMID 28652571 DOI: 10.1038/S41467-017-00044-2  0.412
2016 Li C, Imanishi A, Komatsu N, Terai K, Amano M, Kaibuchi K, Matsuda M. A FRET biosensor for ROCK based on a consensus substrate sequence identified by KISS technology. Cell Structure and Function. PMID 27885213 DOI: 10.1247/Csf.16016  0.364
2016 Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, Fujisawa H, Iwata N, Suga H, Watanabe T, Kaibuchi K, Oiso Y, Arima H, Sugimura Y. Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons. Plos One. 11: e0164544. PMID 27732637 DOI: 10.1371/Journal.Pone.0164544  0.38
2016 Amano M, Nishioka T, Yura Y, Kaibuchi K. Identification of Protein Kinase Substrates by the Kinase-Interacting Substrate Screening (KISS) Approach. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. 72: 14.16.1-14.16.12. PMID 27580705 DOI: 10.1002/Cpcb.8  0.421
2016 Nagai T, Yoshimoto J, Kannon T, Kuroda K, Kaibuchi K. Phosphorylation Signals in Striatal Medium Spiny Neurons. Trends in Pharmacological Sciences. PMID 27546785 DOI: 10.1016/J.Tips.2016.07.003  0.345
2016 Kobayashi K, Sano H, Kato S, Kuroda K, Nakamuta S, Isa T, Nambu A, Kaibuchi K, Kobayashi K. Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway. Neuroscience Letters. PMID 27424794 DOI: 10.1016/J.Neulet.2016.07.020  0.391
2016 Yura Y, Amano M, Takefuji M, Bando T, Suzuki K, Kato K, Hamaguchi T, Shohag MH, Takano T, Funahashi Y, Nakamuta S, Kuroda K, Nishioka T, Murohara T, Kaibuchi K. Focused proteomics revealed a novel Rho-kinase signaling pathway in the heart. Cell Structure and Function. PMID 27334702 DOI: 10.1247/Csf.16011  0.454
2016 Matsuzawa K, Akita H, Watanabe T, Kakeno M, Matsui T, Wang S, Kaibuchi K. PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions. Molecular Biology of the Cell. PMID 26941335 DOI: 10.1091/Mbc.E15-09-0670  0.391
2016 Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, ... ... Kaibuchi K, et al. Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo. Neuron. PMID 26804993 DOI: 10.1016/J.Neuron.2015.12.019  0.355
2015 Yamaoka M, Ando T, Terabayashi T, Okamoto M, Takei M, Nishioka T, Kaibuchi K, Matsunaga K, Ishizaki R, Izumi T, Niki I, Ishizaki T, Kimura T. PI3K regulates endocytosis after insulin secretion via signaling crosstalk between Arf6 and Rab27a. Journal of Cell Science. PMID 26683831 DOI: 10.1242/Jcs.180141  0.367
2015 Xu C, Funahashi Y, Watanabe T, Takano T, Nakamuta S, Namba T, Kaibuchi K. Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14517-32. PMID 26511243 DOI: 10.1523/Jneurosci.1266-15.2015  0.321
2015 Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K. TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. The Journal of Cell Biology. 210: 737-751. PMID 26323690 DOI: 10.1083/Jcb.201412075  0.435
2015 Hasanuzzaman Shohag M, Nishioka T, Uddin Ahammad R, Nakamuta S, Yura Y, Hamaguchi T, Kaibuchi K, Amano M. Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters. Cell Structure and Function. 40: 95-104. PMID 26119529 DOI: 10.1247/Csf.15004  0.425
2015 Amano M, Hamaguchi T, Shohag MH, Kozawa K, Kato K, Zhang X, Yura Y, Matsuura Y, Kataoka C, Nishioka T, Kaibuchi K. Kinase-interacting substrate screening is a novel method to identify kinase substrates. The Journal of Cell Biology. 209: 895-912. PMID 26101221 DOI: 10.1083/Jcb.201412008  0.442
2015 Watanabe T, Wang S, Kaibuchi K. IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics. Cell Structure and Function. 40: 69-77. PMID 26051604 DOI: 10.1247/Csf.15003  0.362
2015 Kobayashi T, Iwamoto Y, Takashima K, Isomura A, Kosodo Y, Kawakami K, Nishioka T, Kaibuchi K, Kageyama R. Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation. The Febs Journal. 282: 2475-87. PMID 25846153 DOI: 10.1111/Febs.13290  0.326
2015 Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, Shinoda T, Hikita T, Muraoka S, Iizuka M, Nimura A, Mizoguchi A, Shiina N, Sokabe M, Okano H, ... ... Kaibuchi K, et al. Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nature Neuroscience. 18: 698-707. PMID 25821909 DOI: 10.1038/Nn.3984  0.478
2015 Nishioka T, Shohag MH, Amano M, Kaibuchi K. Developing novel methods to search for substrates of protein kinases such as Rho-kinase. Biochimica Et Biophysica Acta. PMID 25770685 DOI: 10.1016/J.Bbapap.2015.03.001  0.445
2015 Kedashiro S, Pastuhov SI, Nishioka T, Watanabe T, Kaibuchi K, Matsumoto K, Hanafusa H. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. Journal of Cell Science. 128: 829. PMID 25681495 DOI: 10.1242/Jcs.169102  0.405
2015 Matsui T, Watanabe T, Matsuzawa K, Kakeno M, Okumura N, Sugiyama I, Itoh N, Kaibuchi K. PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity. Molecular Biology of the Cell. 26: 751-61. PMID 25518939 DOI: 10.1091/Mbc.E14-09-1382  0.389
2015 Kedashiro S, Pastuhov SI, Nishioka T, Watanabe T, Kaibuchi K, Matsumoto K, Hanafusa H. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. Journal of Cell Science. 128: 385-96. PMID 25413345 DOI: 10.1242/Jcs.161547  0.404
2015 Hamaguchi T, Nakamuta S, Funahashi Y, Takano T, Nishioka T, Shohag MH, Yura Y, Kaibuchi K, Amano M. In vivo screening for substrates of protein kinase A using a combination of proteomic approaches and pharmacological modulation of kinase activity. Cell Structure and Function. 40: 1-12. PMID 25399539 DOI: 10.1247/Csf.14014  0.429
2014 Hori K, Nagai T, Shan W, Sakamoto A, Taya S, Hashimoto R, Hayashi T, Abe M, Yamazaki M, Nakao K, Nishioka T, Sakimura K, Yamada K, Kaibuchi K, Hoshino M. Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. Cell Reports. 9: 2166-79. PMID 25533347 DOI: 10.1016/J.Celrep.2014.11.045  0.347
2014 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12168-81. PMID 25186760 DOI: 10.1523/Jneurosci.2513-13.2014  0.371
2014 Ota H, Hikita T, Sawada M, Nishioka T, Matsumoto M, Komura M, Ohno A, Kamiya Y, Miyamoto T, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K. Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA. Nature Communications. 5: 4532. PMID 25074242 DOI: 10.1038/Ncomms5532  0.317
2014 Weng L, Enomoto A, Miyoshi H, Takahashi K, Asai N, Morone N, Jiang P, An J, Kato T, Kuroda K, Watanabe T, Asai M, Ishida-Takagishi M, Murakumo Y, Nakashima H, ... Kaibuchi K, et al. Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin. The Embo Journal. 33: 2098-112. PMID 25061227 DOI: 10.15252/Embj.201488289  0.393
2014 Ito Y, Asada A, Kobayashi H, Takano T, Sharma G, Saito T, Ohta Y, Amano M, Kaibuchi K, Hisanaga S. Preferential targeting of p39-activated Cdk5 to Rac1-induced lamellipodia. Molecular and Cellular Neurosciences. 61: 34-45. PMID 24877974 DOI: 10.1016/J.Mcn.2014.05.006  0.331
2014 Kato T, Enomoto A, Watanabe T, Haga H, Ishida S, Kondo Y, Furukawa K, Urano T, Mii S, Weng L, Ishida-Takagishi M, Asai M, Asai N, Kaibuchi K, Murakumo Y, et al. TRIM27/MRTF-B-dependent integrin β1 expression defines leading cells in cancer cell collectives. Cell Reports. 7: 1156-67. PMID 24794433 DOI: 10.1016/J.Celrep.2014.03.068  0.302
2014 Namba T, Kibe Y, Funahashi Y, Nakamuta S, Takano T, Ueno T, Shimada A, Kozawa S, Okamoto M, Shimoda Y, Oda K, Wada Y, Masuda T, Sakakibara A, Igarashi M, ... ... Kaibuchi K, et al. Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron. 81: 814-29. PMID 24559674 DOI: 10.1016/J.Neuron.2013.12.015  0.344
2014 Kakeno M, Matsuzawa K, Matsui T, Akita H, Sugiyama I, Ishidate F, Nakano A, Takashima S, Goto H, Inagaki M, Kaibuchi K, Watanabe T. Plk1 phosphorylates CLIP-170 and regulates its binding to microtubules for chromosome alignment. Cell Structure and Function. 39: 45-59. PMID 24451569 DOI: 10.1247/Csf.14001  0.448
2013 Ota H, Hikita T, Nishioka T, Matsumoto M, Ito J, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K. Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain. Biochemical and Biophysical Research Communications. 442: 16-21. PMID 24211587 DOI: 10.1016/J.Bbrc.2013.10.126  0.351
2013 Kimura T, Yamaoka M, Taniguchi S, Okamoto M, Takei M, Ando T, Iwamatsu A, Watanabe T, Kaibuchi K, Ishizaki T, Niki I. Activated Cdc42-bound IQGAP1 determines the cellular endocytic site. Molecular and Cellular Biology. 33: 4834-43. PMID 24100016 DOI: 10.1128/Mcb.00895-13  0.328
2013 Takefuji M, Yura Y, Kaibuchi K, Murohara T. RhoGEF-mediated vasoconstriction in hypertension. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 36: 930-1. PMID 23966055 DOI: 10.1038/Hr.2013.101  0.307
2013 Funahashi Y, Namba T, Fujisue S, Itoh N, Nakamuta S, Kato K, Shimada A, Xu C, Shan W, Nishioka T, Kaibuchi K. ERK2-mediated phosphorylation of Par3 regulates neuronal polarization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13270-85. PMID 23946386 DOI: 10.1523/Jneurosci.4210-12.2013  0.415
2013 Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano S, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 61: 679-93. PMID 23382131 DOI: 10.1002/Glia.22461  0.306
2013 Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nature Cell Biology. 15: 249-60. PMID 23354168 DOI: 10.1038/Ncb2679  0.352
2013 Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, Yamada K. Neuronal Per Arnt Sim (PAS) domain protein 4 (NPAS4) regulates neurite outgrowth and phosphorylation of synapsin I. The Journal of Biological Chemistry. 288: 2655-64. PMID 23172225 DOI: 10.1074/Jbc.M112.413310  0.414
2012 Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration. The Journal of Cell Biology. 199: 331-45. PMID 23071154 DOI: 10.1083/Jcb.201202041  0.384
2012 Iizuka M, Kimura K, Wang S, Kato K, Amano M, Kaibuchi K, Mizoguchi A. Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues. Cell Structure and Function. 37: 155-75. PMID 22986902 DOI: 10.1247/Csf.12018  0.349
2012 Ishida-Takagishi M, Enomoto A, Asai N, Ushida K, Watanabe T, Hashimoto T, Kato T, Weng L, Matsumoto S, Asai M, Murakumo Y, Kaibuchi K, Kikuchi A, Takahashi M. The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nature Communications. 3: 859. PMID 22643886 DOI: 10.1038/Ncomms1861  0.393
2012 Chiyoda T, Sugiyama N, Shimizu T, Naoe H, Kobayashi Y, Ishizawa J, Arima Y, Tsuda H, Ito M, Kaibuchi K, Aoki D, Ishihama Y, Saya H, Kuninaka S. LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. The Journal of Cell Biology. 197: 625-41. PMID 22641346 DOI: 10.1083/Jcb.201110110  0.436
2012 Kato K, Yazawa T, Taki K, Mori K, Wang S, Nishioka T, Hamaguchi T, Itoh T, Takenawa T, Kataoka C, Matsuura Y, Amano M, Murohara T, Kaibuchi K. The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration. Molecular Biology of the Cell. 23: 2593-604. PMID 22593208 DOI: 10.1091/Mbc.E11-11-0958  0.353
2012 Ohara K, Enomoto A, Kato T, Hashimoto T, Isotani-Sakakibara M, Asai N, Ishida-Takagishi M, Weng L, Nakayama M, Watanabe T, Kato K, Kaibuchi K, Murakumo Y, Hirooka Y, Goto H, et al. Involvement of Girdin in the determination of cell polarity during cell migration. Plos One. 7: e36681. PMID 22574214 DOI: 10.1371/Journal.Pone.0036681  0.385
2012 Okada M, Hozumi Y, Iwazaki K, Misaki K, Yanagida M, Araki Y, Watanabe T, Yagisawa H, Topham MK, Kaibuchi K, Goto K. DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway. Biochemical and Biophysical Research Communications. 420: 479-84. PMID 22450320 DOI: 10.1016/J.Bbrc.2012.03.057  0.353
2012 Watanabe K, Akimoto Y, Yugi K, Uda S, Chung J, Nakamuta S, Kaibuchi K, Kuroda S. Latent process genes for cell differentiation are common decoders of neurite extension length. Journal of Cell Science. 125: 2198-211. PMID 22344266 DOI: 10.1242/Jcs.097709  0.303
2012 Nishioka T, Nakayama M, Amano M, Kaibuchi K. Proteomic screening for Rho-kinase substrates by combining kinase and phosphatase inhibitors with 14-3-3ζ affinity chromatography. Cell Structure and Function. 37: 39-48. PMID 22251793 DOI: 10.1247/Csf.11044  0.46
2011 Nakamuta S, Funahashi Y, Namba T, Arimura N, Picciotto MR, Tokumitsu H, Soderling TR, Sakakibara A, Miyata T, Kamiguchi H, Kaibuchi K. Local application of neurotrophins specifies axons through inositol 1,4,5-trisphosphate, calcium, and Ca2+/calmodulin-dependent protein kinases. Science Signaling. 4: ra76. PMID 22087032 DOI: 10.1126/Scisignal.2002011  0.348
2011 Kuroda K, Yamada S, Tanaka M, Iizuka M, Yano H, Mori D, Tsuboi D, Nishioka T, Namba T, Iizuka Y, Kubota S, Nagai T, Ibi D, Wang R, Enomoto A, ... ... Kaibuchi K, et al. Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Human Molecular Genetics. 20: 4666-83. PMID 21903668 DOI: 10.1093/Hmg/Ddr400  0.49
2011 Renault-Mihara F, Katoh H, Ikegami T, Iwanami A, Mukaino M, Yasuda A, Nori S, Mabuchi Y, Tada H, Shibata S, Saito K, Matsushita M, Kaibuchi K, Okada S, Toyama Y, et al. Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition. Embo Molecular Medicine. 3: 682-96. PMID 21898827 DOI: 10.1016/J.Neures.2011.07.248  0.321
2011 Sato K, Watanabe T, Wang S, Kakeno M, Matsuzawa K, Matsui T, Yokoi K, Murase K, Sugiyama I, Ozawa M, Kaibuchi K. Numb controls E-cadherin endocytosis through p120 catenin with aPKC. Molecular Biology of the Cell. 22: 3103-19. PMID 21775625 DOI: 10.1091/Mbc.E11-03-0274  0.325
2011 Li W, Miki T, Watanabe T, Kakeno M, Sugiyama I, Kaibuchi K, Goshima G. EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells. The Journal of Cell Biology. 193: 973-83. PMID 21646401 DOI: 10.1083/Jcb.201101108  0.356
2011 Takeda S, Fujimoto A, Yamauchi E, Hiyoshi M, Kido H, Watanabe T, Kaibuchi K, Ohta T, Konishi H. Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex. Biochemical and Biophysical Research Communications. 410: 29-33. PMID 21640080 DOI: 10.1016/J.Bbrc.2011.05.099  0.437
2011 Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, et al. Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8109-22. PMID 21632933 DOI: 10.1523/Jneurosci.1130-11.2011  0.367
2011 Naoki H, Nakamuta S, Kaibuchi K, Ishii S. Flexible search for single-axon morphology during neuronal spontaneous polarization. Plos One. 6: e19034. PMID 21559492 DOI: 10.1371/Journal.Pone.0019034  0.326
2011 Morinaka A, Yamada M, Itofusa R, Funato Y, Yoshimura Y, Nakamura F, Yoshimura T, Kaibuchi K, Goshima Y, Hoshino M, Kamiguchi H, Miki H. Thioredoxin mediates oxidation-dependent phosphorylation of CRMP2 and growth cone collapse. Science Signaling. 4: ra26. PMID 21521879 DOI: 10.1126/Scisignal.2001127  0.36
2011 Routray C, Liu C, Yaqoob U, Billadeau DD, Bloch KD, Kaibuchi K, Shah VH, Kang N. Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes. American Journal of Physiology. Cell Physiology. 301: C66-74. PMID 21451103 DOI: 10.1152/Ajpcell.00038.2011  0.46
2011 Qadota H, Miyauchi T, Nahabedian JF, Stirman JN, Lu H, Amano M, Benian GM, Kaibuchi K. PKN-1, a homologue of mammalian PKN, is involved in the regulation of muscle contraction and force transmission in C. elegans. Journal of Molecular Biology. 407: 222-31. PMID 21277858 DOI: 10.1016/J.Jmb.2011.01.039  0.357
2011 Kobayashi K, Masuda T, Takahashi M, Miyazaki J, Nakagawa M, Uchigashima M, Watanabe M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons. The European Journal of Neuroscience. 33: 612-21. PMID 21219475 DOI: 10.1111/J.1460-9568.2010.07554.X  0.375
2011 Heil A, Nazmi AR, Koltzscher M, Poeter M, Austermann J, Assard N, Baudier J, Kaibuchi K, Gerke V. S100P is a novel interaction partner and regulator of IQGAP1. The Journal of Biological Chemistry. 286: 7227-38. PMID 21177863 DOI: 10.1074/Jbc.M110.135095  0.376
2011 Katsumi A, Kiyoi H, Abe A, Tanizaki R, Iwasaki T, Kobayashi M, Matsushita T, Kaibuchi K, Senga T, Kojima T, Kohno T, Hamaguchi M, Naoe T. FLT3/ ITD regulates leukaemia cell adhesion through α4β1 integrin and Pyk2 signalling. European Journal of Haematology. 86: 191-8. PMID 21114537 DOI: 10.1111/J.1600-0609.2010.01556.X  0.399
2011 Katsumi A, Kobayashi M, Matsushita T, Kiyoi H, Kojima T, Maruyama M, Kaibuchi K, Naoe T. RhoH Downregulates Rac Through RhoGAP Family Protein Blood. 118: 4792-4792. DOI: 10.1182/Blood.V118.21.4792.4792  0.428
2011 Funahashi Y, Nakamuta S, Namba T, Kaibuchi K. ERK2 phosphorylates Par3 and controls its transport in axons Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.566  0.322
2011 Nakamuta S, Funahashi Y, Namba T, Kamiguchi H, Kaibuchi K. Neurotrophins regulate neuronal polarity acting through inositol 1, 4, 5-trisphosphate/Ca2+/calmodulin-dependent protein kinase kinase Neuroscience Research. 71: e335. DOI: 10.1016/J.Neures.2011.07.1465  0.445
2011 Tsuboi D, Iizuka Y, Taya S, Shiina N, Okano H, Mikoshiba K, Kaibuchi K. Disrupted-in-Schizoprenia-1 regulates transport of neuronal mRNA for neural plasticity Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1412  0.47
2011 Iizuka Y, Kinoshita T, Tsuboi D, Mori D, Kuroda K, Kaibuchi K. Proteomic analysis reveals novel binging partner of DISC1, a candidate risk gene of schizophrenia Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1308  0.434
2011 Yun J, Nagai T, Hibi Y, Kuroda K, Kaibuchi K, Yamada K. Npas4 regulates neurite outgrowth and phosphoryation of synapsin I Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1025  0.335
2010 Amano M, Nakayama M, Kaibuchi K. Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity. Cytoskeleton (Hoboken, N.J.). 67: 545-54. PMID 20803696 DOI: 10.1002/Cm.20472  0.443
2010 Namba T, Kaibuchi K. Switching DISC1 function in neurogenesis: Dixdc1 selects DISC1 binding partners. Developmental Cell. 19: 7-8. PMID 20643344 DOI: 10.1016/J.Devcel.2010.07.002  0.342
2010 Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, Asano Y, Seguchi O, Higo S, Shintani Y, Asanuma H, Asakura M, Minamino T, Kaibuchi K, Mochizuki N, Kitakaze M, et al. AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nature Cell Biology. 12: 583-90. PMID 20495555 DOI: 10.1038/Ncb2060  0.47
2010 Matsumoto S, Fumoto K, Okamoto T, Kaibuchi K, Kikuchi A. Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells. The Embo Journal. 29: 1192-204. PMID 20224554 DOI: 10.1038/Emboj.2010.26  0.385
2010 Itoh N, Nakayama M, Nishimura T, Fujisue S, Nishioka T, Watanabe T, Kaibuchi K. Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI3-kinase) as Par3 partners by proteomic analysis. Cytoskeleton (Hoboken, N.J.). 67: 297-308. PMID 20191563 DOI: 10.1002/Cm.20444  0.456
2010 Amano M, Tsumura Y, Taki K, Harada H, Mori K, Nishioka T, Kato K, Suzuki T, Nishioka Y, Iwamatsu A, Kaibuchi K. A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase. Plos One. 5: e8704. PMID 20090853 DOI: 10.1371/Journal.Pone.0008704  0.441
2010 Terawaki S, Kitano K, Mori T, Zhai Y, Higuchi Y, Itoh N, Watanabe T, Kaibuchi K, Hakoshima T. The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module. The Embo Journal. 29: 236-50. PMID 19893486 DOI: 10.1038/Emboj.2009.323  0.31
2010 Watanabe T, Wang S, Matsuzawa K, Sato K, Kakeno M, Itoh N, Kaibuchi K. Targeting of Tiam1 to focal adhesion through talin for Rac1 activation and cell migration F1000research. 1. DOI: 10.7490/F1000Research.35.1  0.309
2010 Amano M, Kaibuchi K. A proteomic approach for comprehensively screening substrates of protein kinases Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.398  0.367
2010 Kobayashi K, Kato S, Kaibuchi K, Kobayashi K. Conditional suppression of rho GTPase signaling pathway in specific neuronal types with Cre-loxP recombination driven by double lentiviral vector system Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2549  0.303
2010 Funahashi Y, Fujisue S, Ito N, Yamaguchi R, Nakamuta S, Namba T, Kaibuchi K. ERK2-mediated phosphorylation of Par3 affects axon specification by modulating its interaction with KIF3A Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2190  0.358
2010 Yun J, Nagai T, Hibi Y, Koike H, Nitta A, Kuroda K, Kaibuchi K, Yamada K. The role of Npas4 in neurite outgrowth and phosphorylated synapsin I expression in Neuro2a cells and primary cultured hippocampal neurons Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.1112  0.353
2009 Watanabe T, Sato K, Kaibuchi K. Cadherin-mediated intercellular adhesion and signaling cascades involving small GTPases. Cold Spring Harbor Perspectives in Biology. 1: a003020. PMID 20066109 DOI: 10.1101/Cshperspect.A003020  0.327
2009 Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, ... ... Kaibuchi K, et al. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron. 63: 774-87. PMID 19778507 DOI: 10.1016/J.Neuron.2009.08.015  0.36
2009 Hou ST, Jiang SX, Aylsworth A, Ferguson G, Slinn J, Hu H, Leung T, Kappler J, Kaibuchi K. CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity. Journal of Neurochemistry. 111: 870-81. PMID 19735446 DOI: 10.1111/J.1471-4159.2009.06375.X  0.382
2009 Arimura N, Hattori A, Kimura T, Nakamuta S, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K. CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity. Journal of Neurochemistry. 111: 380-90. PMID 19659462 DOI: 10.1111/J.1471-4159.2009.06317.X  0.346
2009 Watanabe T, Noritake J, Kakeno M, Matsui T, Harada T, Wang S, Itoh N, Sato K, Matsuzawa K, Iwamatsu A, Galjart N, Kaibuchi K. Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules. Journal of Cell Science. 122: 2969-79. PMID 19638411 DOI: 10.1242/Jcs.046649  0.405
2009 Hikita T, Taya S, Fujino Y, Taneichi-Kuroda S, Ohta K, Tsuboi D, Shinoda T, Kuroda K, Funahashi Y, Uraguchi-Asaki J, Hashimoto R, Kaibuchi K. Proteomic analysis reveals novel binding partners of dysbindin, a schizophrenia-related protein. Journal of Neurochemistry. 110: 1567-74. PMID 19573021 DOI: 10.1111/J.1471-4159.2009.06257.X  0.336
2009 Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G. TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases. The Journal of Biological Chemistry. 284: 22059-66. PMID 19535326 DOI: 10.1016/J.Neures.2009.09.561  0.392
2009 Hata K, Kaibuchi K, Inagaki S, Yamashita T. Unc5B associates with LARG to mediate the action of repulsive guidance molecule. The Journal of Cell Biology. 184: 737-50. PMID 19273616 DOI: 10.1083/Jcb.200807029  0.412
2009 Mori K, Amano M, Takefuji M, Kato K, Morita Y, Nishioka T, Matsuura Y, Murohara T, Kaibuchi K. Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP. The Journal of Biological Chemistry. 284: 5067-76. PMID 19103606 DOI: 10.1074/Jbc.M806853200  0.436
2009 Funahashi Y, Arimura N, Nakamuta S, Kaibuchi K. Identification of PI 3-kinase as an Slp1-interacting protein by proteomic analysis Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1089  0.412
2008 Sugimoto M, Inoko A, Shiromizu T, Nakayama M, Zou P, Yonemura S, Hayashi Y, Izawa I, Sasoh M, Uji Y, Kaibuchi K, Kiyono T, Inagaki M. The keratin-binding protein Albatross regulates polarization of epithelial cells. The Journal of Cell Biology. 183: 19-28. PMID 18838552 DOI: 10.1083/Jcb.200803133  0.351
2008 Iwasaki T, Katsumi A, Kiyoi H, Tanizaki R, Ishikawa Y, Ozeki K, Kobayashi M, Abe A, Matsushita T, Watanabe T, Amano M, Kojima T, Kaibuchi K, Naoe T. Prognostic implication and biological roles of RhoH in acute myeloid leukaemia. European Journal of Haematology. 81: 454-60. PMID 18691253 DOI: 10.1111/J.1600-0609.2008.01132.X  0.319
2008 Yamashiro S, Yamakita Y, Totsukawa G, Goto H, Kaibuchi K, Ito M, Hartshorne DJ, Matsumura F. Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. Developmental Cell. 14: 787-97. PMID 18477460 DOI: 10.1016/J.Devcel.2008.02.013  0.45
2008 Nakayama M, Goto TM, Sugimoto M, Nishimura T, Shinagawa T, Ohno S, Amano M, Kaibuchi K. Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. Developmental Cell. 14: 205-15. PMID 18267089 DOI: 10.1016/J.Devcel.2007.11.021  0.446
2008 Patrakitkomjorn S, Kobayashi D, Morikawa T, Wilson MM, Tsubota N, Irie A, Ozawa T, Aoki M, Arimura N, Kaibuchi K, Saya H, Araki N. Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2. The Journal of Biological Chemistry. 283: 9399-413. PMID 18218617 DOI: 10.1074/Jbc.M708206200  0.448
2008 Yamamoto M, Ramirez SH, Sato S, Kiyota T, Cerny RL, Kaibuchi K, Persidsky Y, Ikezu T. Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells. The American Journal of Pathology. 172: 521-33. PMID 18187566 DOI: 10.2353/Ajpath.2008.070076  0.376
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, ... ... Kaibuchi K, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024  0.361
2007 Qadota H, Mercer KB, Miller RK, Kaibuchi K, Benian GM. Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle. Molecular Biology of the Cell. 18: 4317-26. PMID 17761533 DOI: 10.1091/Mbc.E07-03-0278  0.333
2007 Sugimoto M, Nakayama M, Goto TM, Amano M, Komori K, Kaibuchi K. Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells. Biochemical and Biophysical Research Communications. 361: 462-7. PMID 17651694 DOI: 10.1016/J.Bbrc.2007.07.030  0.441
2007 Brandt DT, Marion S, Griffiths G, Watanabe T, Kaibuchi K, Grosse R. Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation. The Journal of Cell Biology. 178: 193-200. PMID 17620407 DOI: 10.1083/Jcb.200612071  0.384
2007 Nishimura T, Kaibuchi K. Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Developmental Cell. 13: 15-28. PMID 17609107 DOI: 10.1016/J.Devcel.2007.05.003  0.424
2007 Mishima M, Maesaki R, Kasa M, Watanabe T, Fukata M, Kaibuchi K, Hakoshima T. Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. Proceedings of the National Academy of Sciences of the United States of America. 104: 10346-51. PMID 17563362 DOI: 10.1073/Pnas.0703876104  0.309
2007 Yagita Y, Kitagawa K, Sasaki T, Terasaki Y, Todo K, Omura-Matsuoka E, Kaibuchi K, Hori M. Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia. Journal of Neuroscience Research. 85: 2460-9. PMID 17526023 DOI: 10.1002/Jnr.21375  0.394
2007 Takefuji M, Mori K, Morita Y, Arimura N, Nishimura T, Nakayama M, Hoshino M, Iwamatsu A, Murohara T, Kaibuchi K, Amano M. Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation. Biochemical and Biophysical Research Communications. 355: 788-94. PMID 17320046 DOI: 10.1016/J.Bbrc.2007.02.028  0.485
2007 Arimura N, Kaibuchi K. Neuronal polarity: from extracellular signals to intracellular mechanisms. Nature Reviews. Neuroscience. 8: 194-205. PMID 17311006 DOI: 10.1038/Nrn2056  0.317
2007 Wang S, Watanabe T, Noritake J, Fukata M, Yoshimura T, Itoh N, Harada T, Nakagawa M, Matsuura Y, Arimura N, Kaibuchi K. IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth. Journal of Cell Science. 120: 567-77. PMID 17244649 DOI: 10.1242/Jcs.03356  0.383
2007 Shinoda T, Taya S, Tsuboi D, Hikita T, Matsuzawa R, Kuroda S, Iwamatsu A, Kaibuchi K. DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4-14. PMID 17202467 DOI: 10.1523/Jneurosci.3825-06.2007  0.359
2007 Kobayashi K, Masuda T, Takahashi M, Miyazaki J, Nakagawa M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Key role of Rho/Rho-kinase signaling in hindbrain motor axon patterning Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.908  0.343
2007 Taya S, Uraguchi-Asaki J, Kuroda K, Kaibuchi K. Regulation of DISC1 through phosphorylation by ERK Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.382  0.426
2006 Abe K, Tawara S, Oi K, Hizume T, Uwatoku T, Fukumoto Y, Kaibuchi K, Shimokawa H. Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice. Journal of Cardiovascular Pharmacology. 48: 280-5. PMID 17204906 DOI: 10.1097/01.Fjc.0000248244.64430.4A  0.362
2006 Yoshimura T, Arimura N, Kaibuchi K. Molecular mechanisms of axon specification and neuronal disorders. Annals of the New York Academy of Sciences. 1086: 116-25. PMID 17185510 DOI: 10.1196/Annals.1377.013  0.37
2006 Kim WY, Zhou FQ, Zhou J, Yokota Y, Wang YM, Yoshimura T, Kaibuchi K, Woodgett JR, Anton ES, Snider WD. Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth. Neuron. 52: 981-96. PMID 17178402 DOI: 10.1016/J.Neuron.2006.10.031  0.326
2006 Yoshimura T, Arimura N, Kaibuchi K. Signaling networks in neuronal polarization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10626-30. PMID 17050700 DOI: 10.1523/Jneurosci.3824-06.2006  0.375
2006 Ma Z, Kanai M, Kawamura K, Kaibuchi K, Ye K, Fukasawa K. Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication. Molecular and Cellular Biology. 26: 9016-34. PMID 17015463 DOI: 10.1128/Mcb.01383-06  0.378
2006 Jin HG, Yamashita H, Nagano Y, Fukuba H, Hiji M, Ohtsuki T, Takahashi T, Kohriyama T, Kaibuchi K, Matsumoto M. Hypoxia-induced upregulation of endothelial small G protein RhoA and Rho-kinase/ROCK2 inhibits eNOS expression. Neuroscience Letters. 408: 62-7. PMID 16996686 DOI: 10.1016/J.Neulet.2006.08.038  0.404
2006 Maeda A, Ozaki Y, Sivakumaran S, Akiyama T, Urakubo H, Usami A, Sato M, Kaibuchi K, Kuroda S. Ca2+ -independent phospholipase A2-dependent sustained Rho-kinase activation exhibits all-or-none response. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 1071-83. PMID 16923126 DOI: 10.1111/J.1365-2443.2006.01001.X  0.448
2006 Yamaguchi H, Miwa Y, Kasa M, Kitano K, Amano M, Kaibuchi K, Hakoshima T. Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632. Journal of Biochemistry. 140: 305-11. PMID 16891330 DOI: 10.1093/Jb/Mvj172  0.387
2006 Ito Y, Oinuma I, Katoh H, Kaibuchi K, Negishi M. Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse. Embo Reports. 7: 704-9. PMID 16799460 DOI: 10.1038/Sj.Embor.7400737  0.356
2006 Oguri T, Inoko A, Shima H, Izawa I, Arimura N, Yamaguchi T, Inagaki N, Kaibuchi K, Kikuchi K, Inagaki M. Vimentin-Ser82 as a memory phosphorylation site in astrocytes. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 531-40. PMID 16629905 DOI: 10.1111/J.1365-2443.2006.00961.X  0.412
2006 Mimura F, Yamagishi S, Arimura N, Fujitani M, Kubo T, Kaibuchi K, Yamashita T. Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism. The Journal of Biological Chemistry. 281: 15970-9. PMID 16595691 DOI: 10.1074/Jbc.M510934200  0.436
2006 Tanaka T, Nishimura D, Wu RC, Amano M, Iso T, Kedes L, Nishida H, Kaibuchi K, Hamamori Y. Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase. The Journal of Biological Chemistry. 281: 15320-9. PMID 16574662 DOI: 10.1074/Jbc.M510954200  0.416
2006 Yamaguchi H, Kasa M, Amano M, Kaibuchi K, Hakoshima T. Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil. Structure (London, England : 1993). 14: 589-600. PMID 16531242 DOI: 10.1016/J.Str.2005.11.024  0.434
2006 Persidsky Y, Heilman D, Haorah J, Zelivyanskaya M, Persidsky R, Weber GA, Shimokawa H, Kaibuchi K, Ikezu T. Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood. 107: 4770-80. PMID 16478881 DOI: 10.1182/Blood-2005-11-4721  0.359
2006 Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M. Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. Cellular Signalling. 18: 1408-16. PMID 16431080 DOI: 10.1016/J.Cellsig.2005.11.001  0.364
2006 Tahimic CG, Tomimatsu N, Nishigaki R, Fukuhara A, Toda T, Kaibuchi K, Shiota G, Oshimura M, Kurimasa A. Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells. Biochemical and Biophysical Research Communications. 340: 1244-50. PMID 16414354 DOI: 10.1016/J.Bbrc.2005.12.132  0.451
2006 Nishimura T, Yamaguchi T, Tokunaga A, Hara A, Hamaguchi T, Kato K, Iwamatsu A, Okano H, Kaibuchi K. Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Molecular Biology of the Cell. 17: 1273-85. PMID 16394100 DOI: 10.1091/Mbc.E05-07-0700  0.376
2006 Yoshimura T, Arimura N, Kawano Y, Kawabata S, Wang S, Kaibuchi K. Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway. Biochemical and Biophysical Research Communications. 340: 62-8. PMID 16343426 DOI: 10.1016/J.Bbrc.2005.11.147  0.432
2006 Sobue G, Takahashi M, Yoshida J, Kaibuchi K, Naoe T, Lahiri DK. Integrated molecular medicine for neuronal and neoplastic disorders Annals of the New York Academy of Sciences. 1086: xi-xii. DOI: 10.1196/Annals.1377.015  0.333
2005 Arimura N, Kaibuchi K. Key regulators in neuronal polarity. Neuron. 48: 881-4. PMID 16364893 DOI: 10.1016/J.Neuron.2005.11.007  0.348
2005 Watanabe T, Noritake J, Kaibuchi K. Roles of IQGAP1 in cell polarization and migration. Novartis Foundation Symposium. 269: 92-101; discussion 1. PMID 16355537 DOI: 10.1002/047001766X.Ch9  0.345
2005 Arimura N, Ménager C, Kawano Y, Yoshimura T, Kawabata S, Hattori A, Fukata Y, Amano M, Goshima Y, Inagaki M, Morone N, Usukura J, Kaibuchi K. Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Molecular and Cellular Biology. 25: 9973-84. PMID 16260611 DOI: 10.1128/Mcb.25.22.9973-9984.2005  0.443
2005 Kawano Y, Yoshimura T, Tsuboi D, Kawabata S, Kaneko-Kawano T, Shirataki H, Takenawa T, Kaibuchi K. CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation. Molecular and Cellular Biology. 25: 9920-35. PMID 16260607 DOI: 10.1128/Mcb.25.22.9920-9935.2005  0.312
2005 Tsuboi D, Hikita T, Qadota H, Amano M, Kaibuchi K. Regulatory machinery of UNC-33 Ce-CRMP localization in neurites during neuronal development in Caenorhabditis elegans. Journal of Neurochemistry. 95: 1629-41. PMID 16236031 DOI: 10.1111/J.1471-4159.2005.03490.X  0.359
2005 Kaneko T, Maeda A, Takefuji M, Aoyama H, Nakayama M, Kawabata S, Kawano Y, Iwamatsu A, Amano M, Kaibuchi K. Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 10: 973-87. PMID 16164598 DOI: 10.1111/J.1365-2443.2005.00895.X  0.423
2005 Enomoto A, Murakami H, Asai N, Morone N, Watanabe T, Kawai K, Murakumo Y, Usukura J, Kaibuchi K, Takahashi M. Akt/PKB regulates actin organization and cell motility via Girdin/APE. Developmental Cell. 9: 389-402. PMID 16139227 DOI: 10.1016/J.Devcel.2005.08.001  0.459
2005 Hikita T, Qadota H, Tsuboi D, Taya S, Moerman DG, Kaibuchi K. Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure. Biochemical and Biophysical Research Communications. 335: 139-45. PMID 16055082 DOI: 10.1016/J.Bbrc.2005.07.068  0.353
2005 Kimura T, Watanabe H, Iwamatsu A, Kaibuchi K. Tubulin and CRMP-2 complex is transported via Kinesin-1. Journal of Neurochemistry. 93: 1371-82. PMID 15935053 DOI: 10.1111/J.1471-4159.2005.03063.X  0.315
2005 Tamaru S, Fukuta T, Kaibuchi K, Matsuoka Y, Shiku H, Nishikawa M. Rho-kinase induces association of adducin with the cytoskeleton in platelet activation. Biochemical and Biophysical Research Communications. 332: 347-51. PMID 15910744 DOI: 10.1016/J.Bbrc.2005.04.127  0.385
2005 Noritake J, Watanabe T, Sato K, Wang S, Kaibuchi K. IQGAP1: a key regulator of adhesion and migration. Journal of Cell Science. 118: 2085-92. PMID 15890984 DOI: 10.1242/Jcs.02379  0.366
2005 Nishimura T, Yamaguchi T, Kato K, Yoshizawa M, Nabeshima Y, Ohno S, Hoshino M, Kaibuchi K. PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. Nature Cell Biology. 7: 270-7. PMID 15723051 DOI: 10.1038/Ncb1227  0.429
2005 Watanabe T, Noritake J, Kaibuchi K. Regulation of microtubules in cell migration. Trends in Cell Biology. 15: 76-83. PMID 15695094 DOI: 10.1016/J.Tcb.2004.12.006  0.334
2005 Nakayama M, Amano M, Katsumi A, Kaneko T, Kawabata S, Takefuji M, Kaibuchi K. Rho-kinase and myosin II activities are required for cell type and environment specific migration. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 10: 107-17. PMID 15676022 DOI: 10.1111/J.1365-2443.2005.00823.X  0.412
2005 Abe K, Morikawa K, Hizume T, Uwatoku T, Oi K, Seto M, Ikegaki I, Asano T, Kaibuchi K, Shimokawa H. Prostacyclin does not inhibit rho-kinase: an implication for the treatment of pulmonary hypertension. Journal of Cardiovascular Pharmacology. 45: 120-4. PMID 15654260 DOI: 10.1097/01.Fjc.0000151898.65260.6A  0.404
2005 Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K. GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell. 120: 137-49. PMID 15652488 DOI: 10.1016/J.Cell.2004.11.012  0.352
2004 Birukova AA, Birukov KG, Smurova K, Adyshev D, Kaibuchi K, Alieva I, Garcia JG, Verin AD. Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1879-90. PMID 15576491 DOI: 10.1096/Fj.04-2328Com  0.442
2004 Watanabe T, Wang S, Noritake J, Sato K, Fukata M, Takefuji M, Nakagawa M, Izumi N, Akiyama T, Kaibuchi K. Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Developmental Cell. 7: 871-83. PMID 15572129 DOI: 10.1016/J.Devcel.2004.10.017  0.355
2004 Nakaya Y, Kuroda S, Katagiri YT, Kaibuchi K, Takahashi Y. Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Developmental Cell. 7: 425-38. PMID 15363416 DOI: 10.1016/J.Devcel.2004.08.003  0.343
2004 Ito K, Hirooka Y, Sagara Y, Kimura Y, Kaibuchi K, Shimokawa H, Takeshita A, Sunagawa K. Inhibition of Rho-kinase in the brainstem augments baroreflex control of heart rate in rats. Hypertension. 44: 478-83. PMID 15353514 DOI: 10.1161/01.Hyp.0000143120.24612.68  0.353
2004 Birukova AA, Smurova K, Birukov KG, Usatyuk P, Liu F, Kaibuchi K, Ricks-Cord A, Natarajan V, Alieva I, Garcia JG, Verin AD. Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms. Journal of Cellular Physiology. 201: 55-70. PMID 15281089 DOI: 10.1002/Jcp.20055  0.415
2004 Hiroki J, Shimokawa H, Higashi M, Morikawa K, Kandabashi T, Kawamura N, Kubota T, Ichiki T, Amano M, Kaibuchi K, Takeshita A. Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology. 37: 537-46. PMID 15276023 DOI: 10.1016/J.Yjmcc.2004.05.008  0.448
2004 Kawabata S, Usukura J, Morone N, Ito M, Iwamatsu A, Kaibuchi K, Amano M. Interaction of Rho-kinase with myosin II at stress fibres. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 653-60. PMID 15265008 DOI: 10.1111/J.1356-9597.2004.00749.X  0.367
2004 Ren XD, Wang R, Li Q, Kahek LA, Kaibuchi K, Clark RA. Disruption of Rho signal transduction upon cell detachment. Journal of Cell Science. 117: 3511-8. PMID 15226371 DOI: 10.1242/Jcs.01205  0.475
2004 Moriki N, Ito M, Seko T, Kureishi Y, Okamoto R, Nakakuki T, Kongo M, Isaka N, Kaibuchi K, Nakano T. RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 27: 263-70. PMID 15127884 DOI: 10.1291/Hypres.27.263  0.433
2004 Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Tsutsui H, Kaibuchi K, Takeshita A. Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice. Circulation. 109: 2234-9. PMID 15096457 DOI: 10.1161/01.Cir.0000127939.16111.58  0.355
2004 Takami A, Iwakubo M, Okada Y, Kawata T, Odai H, Takahashi N, Shindo K, Kimura K, Tagami Y, Miyake M, Fukushima K, Inagaki M, Amano M, Kaibuchi K, Iijima H. Design and synthesis of Rho kinase inhibitors (I). Bioorganic & Medicinal Chemistry. 12: 2115-37. PMID 15080913 DOI: 10.1016/J.Bmc.2004.02.025  0.38
2004 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3480-8. PMID 15071095 DOI: 10.1523/Jneurosci.0295-04.2004  0.395
2004 Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K. Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity. Nature Cell Biology. 6: 328-34. PMID 15048131 DOI: 10.1038/Ncb1118  0.349
2004 Ménager C, Arimura N, Fukata Y, Kaibuchi K. PIP3 is involved in neuronal polarization and axon formation. Journal of Neurochemistry. 89: 109-18. PMID 15030394 DOI: 10.1046/J.1471-4159.2004.02302.X  0.364
2004 Ito K, Hirooka Y, Kishi T, Kimura Y, Kaibuchi K, Shimokawa H, Takeshita A. Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition. Hypertension. 43: 156-62. PMID 14732730 DOI: 10.1161/01.Hyp.0000114602.82140.A4  0.365
2004 Birukova AA, Smurova K, Birukov KG, Kaibuchi K, Garcia JG, Verin AD. Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvascular Research. 67: 64-77. PMID 14709404 DOI: 10.1016/J.Mvr.2003.09.007  0.446
2004 Noritake J, Fukata M, Sato K, Nakagawa M, Watanabe T, Izumi N, Wang S, Fukata Y, Kaibuchi K. Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. Molecular Biology of the Cell. 15: 1065-76. PMID 14699063 DOI: 10.1091/Mbc.E03-08-0582  0.343
2004 Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K, Takeshit A. Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circulation Research. 94: 385-93. PMID 14670839 DOI: 10.1161/01.Res.0000111804.34509.94  0.327
2004 Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Kaibuchi K, Takeshita A. Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice. Circulation Research. 94: 46-52. PMID 14615290 DOI: 10.1161/01.Res.0000107196.21335.2B  0.345
2004 Arimura N, Menager C, Fukata Y, Kaibuchi K. Role of CRMP-2 in neuronal polarity. Journal of Neurobiology. 58: 34-47. PMID 14598368 DOI: 10.1002/Neu.10269  0.316
2003 Amano M, Kaneko T, Maeda A, Nakayama M, Ito M, Yamauchi T, Goto H, Fukata Y, Oshiro N, Shinohara A, Iwamatsu A, Kaibuchi K. Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase. Journal of Neurochemistry. 87: 780-90. PMID 14535960 DOI: 10.1046/J.1471-4159.2003.02054.X  0.428
2003 Fukata M, Nakagawa M, Kaibuchi K. Roles of Rho-family GTPases in cell polarisation and directional migration. Current Opinion in Cell Biology. 15: 590-7. PMID 14519394 DOI: 10.1016/S0955-0674(03)00097-8  0.392
2003 Becknell B, Shen T, Maghraby E, Taya S, Kaibuchi K, Caligiuri MA, Marcucci G. Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development. Cell and Tissue Research. 314: 361-6. PMID 14513355 DOI: 10.1007/S00441-003-0802-5  0.347
2003 Shimizu T, Ihara K, Maesaki R, Amano M, Kaibuchi K, Hakoshima T. Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. The Journal of Biological Chemistry. 278: 46046-51. PMID 12954645 DOI: 10.1074/Jbc.M306458200  0.436
2003 Nishimura T, Fukata Y, Kato K, Yamaguchi T, Matsuura Y, Kamiguchi H, Kaibuchi K. CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth. Nature Cell Biology. 5: 819-26. PMID 12942088 DOI: 10.1038/Ncb1039  0.324
2003 Ménager C, Kaibuchi K. [Rho proteins: their function in neurons]. Mã©Decine Sciences : M/S. 19: 358-63. PMID 12836419 DOI: 10.1051/Medsci/2003193358  0.323
2003 Tharaux PL, Bukoski RC, Rocha PN, Crowley SD, Ruiz P, Nataraj C, Howell DN, Kaibuchi K, Spurney RF, Coffman TM. Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 96-105. PMID 12816987 DOI: 10.4049/Jimmunol.171.1.96  0.439
2003 Ito K, Hirooka Y, Sakai K, Kishi T, Kaibuchi K, Shimokawa H, Takeshita A. Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension. Circulation Research. 92: 1337-43. PMID 12791705 DOI: 10.1161/01.Res.0000079941.59846.D4  0.38
2003 Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just I. Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex. The Journal of Biological Chemistry. 278: 28523-7. PMID 12750364 DOI: 10.1074/Jbc.M301915200  0.402
2003 Su L, Hattori M, Moriyama M, Murata N, Harazaki M, Kaibuchi K, Minato N. AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1. The Journal of Biological Chemistry. 278: 15232-8. PMID 12590145 DOI: 10.1074/Jbc.M211888200  0.348
2002 Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Molecular and Cellular Biology. 22: 8467-77. PMID 12446767 DOI: 10.1128/Mcb.22.24.8467-8477.2002  0.44
2002 Maeda A, Amano M, Fukata Y, Kaibuchi K. Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells. Biochemical and Biophysical Research Communications. 297: 1231-7. PMID 12372419 DOI: 10.1016/S0006-291X(02)02342-2  0.381
2002 Kawano Y, Yoshimura T, Kaibuchi K. [Involvement of small GTPase Rho in cardiovascular diseases]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 120: 149-58. PMID 12271510 DOI: 10.1254/Fpj.120.149  0.363
2002 Fukata Y, Itoh TJ, Kimura T, Ménager C, Nishimura T, Shiromizu T, Watanabe H, Inagaki N, Iwamatsu A, Hotani H, Kaibuchi K. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nature Cell Biology. 4: 583-91. PMID 12134159 DOI: 10.1038/Ncb825  0.312
2002 Fukata M, Watanabe T, Noritake J, Nakagawa M, Yamaga M, Kuroda S, Matsuura Y, Iwamatsu A, Perez F, Kaibuchi K. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell. 109: 873-85. PMID 12110184 DOI: 10.1016/S0092-8674(02)00800-0  0.33
2002 Kawano Y, Yoshimura T, Kaibuchi K. Smooth muscle contraction by small GTPase Rho. Nagoya Journal of Medical Science. 65: 1-8. PMID 12083286 DOI: 10.18999/Nagjms.65.1-2.1  0.344
2002 Soto MC, Qadota H, Kasuya K, Inoue M, Tsuboi D, Mello CC, Kaibuchi K. The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. Genes & Development. 16: 620-32. PMID 11877381 DOI: 10.1101/Gad.955702  0.35
2002 Kataoka C, Egashira K, Inoue S, Takemoto M, Ni W, Koyanagi M, Kitamoto S, Usui M, Kaibuchi K, Shimokawa H, Takeshita A. Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. Hypertension. 39: 245-50. PMID 11847192 DOI: 10.1161/Hy0202.103271  0.4
2002 Kandabashi T, Shimokawa H, Mukai Y, Matoba T, Kunihiro I, Morikawa K, Ito M, Takahashi S, Kaibuchi K, Takeshita A. Involvement of rho-kinase in agonists-induced contractions of arteriosclerotic human arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 243-8. PMID 11834523 DOI: 10.1161/Hq0202.104274  0.384
2001 Morishige K, Shimokawa H, Eto Y, Hoshijima M, Kaibuchi K, Takeshita A. In vivo gene transfer of dominant-negative rho-kinase induces regression of coronary arteriosclerosis in pigs. Annals of the New York Academy of Sciences. 947: 407-11. PMID 11795302 DOI: 10.1111/J.1749-6632.2001.Tb03974.X  0.366
2001 Fukata M, Kaibuchi K. Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nature Reviews. Molecular Cell Biology. 2: 887-97. PMID 11733768 DOI: 10.1038/35103068  0.358
2001 Pantaleon M, Kanai-Azuma M, Mattick JS, Kaibuchi K, Kaye PL, Wood SA. FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mechanisms of Development. 109: 151-60. PMID 11731229 DOI: 10.1016/S0925-4773(01)00551-2  0.318
2001 Delon J, Kaibuchi K, Germain RN. Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity. 15: 691-701. PMID 11728332 DOI: 10.1016/S1074-7613(01)00231-X  0.409
2001 Taya S, Inagaki N, Sengiku H, Makino H, Iwamatsu A, Urakawa I, Nagao K, Kataoka S, Kaibuchi K. Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. The Journal of Cell Biology. 155: 809-20. PMID 11724822 DOI: 10.1083/Jcb.200106139  0.383
2001 Kato M, Seki N, Sugano S, Hashimoto K, Masuho Y, Muramatsu M, Kaibuchi K, Nakafuku M. Identification of sonic hedgehog-responsive genes using cDNA microarray. Biochemical and Biophysical Research Communications. 289: 472-8. PMID 11716497 DOI: 10.1006/Bbrc.2001.5976  0.351
2001 Sato M, Tani E, Fujikawa H, Yamaura I, Arita N, Kaibuchi K. Importance of Rho-kinase-mediated phosphorylation of myosin light chain in vasospasm. Acta Neurochirurgica. Supplement. 77: 49-54. PMID 11563308 DOI: 10.1007/978-3-7091-6232-3_12  0.437
2001 Ohnaka K, Shimoda S, Nawata H, Shimokawa H, Kaibuchi K, Iwamoto Y, Takayanagi R. Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts. Biochemical and Biophysical Research Communications. 287: 337-42. PMID 11554731 DOI: 10.1006/Bbrc.2001.5597  0.418
2001 Szászi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J. Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. The Journal of Biological Chemistry. 276: 40761-8. PMID 11522794 DOI: 10.1074/Jbc.M106724200  0.434
2001 Zong H, Kaibuchi K, Quilliam LA. The insert region of RhoA is essential for Rho kinase activation and cellular transformation. Molecular and Cellular Biology. 21: 5287-98. PMID 11463812 DOI: 10.1128/Mcb.21.16.5287-5298.2001  0.446
2001 Funakoshi Y, Ichiki T, Shimokawa H, Egashira K, Takeda K, Kaibuchi K, Takeya M, Yoshimura T, Takeshita A. Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension. 38: 100-4. PMID 11463768 DOI: 10.1161/01.Hyp.38.1.100  0.393
2001 Shimokawa H, Morishige K, Miyata K, Kandabashi T, Eto Y, Ikegaki I, Asano T, Kaibuchi K, Takeshita A. Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovascular Research. 51: 169-77. PMID 11399259 DOI: 10.1016/S0008-6363(01)00291-7  0.343
2001 Shah V, Bharadwaj S, Kaibuchi K, Prasad GL. Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway. Oncogene. 20: 2112-21. PMID 11360195 DOI: 10.1038/Sj.Onc.1204291  0.38
2001 Katoh K, Kano Y, Amano M, Kaibuchi K, Fujiwara K. Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. American Journal of Physiology. Cell Physiology. 280: C1669-79. PMID 11350763 DOI: 10.1152/Ajpcell.2001.280.6.C1669  0.327
2001 Katoh K, Kano Y, Amano M, Onishi H, Kaibuchi K, Fujiwara K. Rho-kinase--mediated contraction of isolated stress fibers. The Journal of Cell Biology. 153: 569-84. PMID 11331307 DOI: 10.1083/Jcb.153.3.569  0.412
2001 Morishige K, Shimokawa H, Eto Y, Kandabashi T, Miyata K, Matsumoto Y, Hoshijima M, Kaibuchi K, Takeshita A. Adenovirus-mediated transfer of dominant-negative rho-kinase induces a regression of coronary arteriosclerosis in pigs in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 548-54. PMID 11304471 DOI: 10.1161/01.Atv.21.4.548  0.379
2001 Araki S, Ito M, Kureishi Y, Feng J, Machida H, Isaka N, Amano M, Kaibuchi K, Hartshorne DJ, Nakano T. Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase. Pflã¼Gers Archiv : European Journal of Physiology. 441: 596-603. PMID 11294240 DOI: 10.1007/S004240000462  0.444
2001 Mukai Y, Shimokawa H, Matoba T, Kandabashi T, Satoh S, Hiroki J, Kaibuchi K, Takeshita A. Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1062-4. PMID 11292668 DOI: 10.1096/Fj.00-0735Fje  0.338
2001 Fukata M, Nakagawa M, Itoh N, Kawajiri A, Yamaga M, Kuroda S, Kaibuchi K. Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering. Molecular and Cellular Biology. 21: 2165-83. PMID 11238950 DOI: 10.1128/Mcb.21.6.2165-2183.2001  0.33
2001 Shibata R, Kai H, Seki Y, Kato S, Morimatsu M, Kaibuchi K, Imaizumi T. Role of Rho-associated kinase in neointima formation after vascular injury. Circulation. 103: 284-9. PMID 11208690 DOI: 10.1161/01.Cir.103.2.284  0.392
2001 Fukata Y, Amano M, Kaibuchi K. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends in Pharmacological Sciences. 22: 32-9. PMID 11165670 DOI: 10.1016/S0165-6147(00)01596-0  0.36
2001 Keizo O, Shimoda S, Nawata H, Shimokawa H, Kaibuchi K, Iwamoto Y, Takayanagi R. Erratum: Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of rho-associated kinase in human osteoblasts (Biochemical and Biophysical Research Communications (2001) 287:2 (337-342)) Biochemical and Biophysical Research Communications. 287: 1167. DOI: 10.1006/Bbrc.2001.5717  0.341
2000 Amano M, Fukata Y, Kaibuchi K. Regulation and functions of Rho-associated kinase. Experimental Cell Research. 261: 44-51. PMID 11082274 DOI: 10.1006/Excr.2000.5046  0.444
2000 Miyata K, Shimokawa H, Kandabashi T, Higo T, Morishige K, Eto Y, Egashira K, Kaibuchi K, Takeshita A. Rho-kinase is involved in macrophage-mediated formation of coronary vascular lesions in pigs in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2351-8. PMID 11073837 DOI: 10.1161/01.Atv.20.11.2351  0.371
2000 Izawa T, Fukata Y, Kimura T, Iwamatsu A, Dohi K, Kaibuchi K. Elongation factor-1 alpha is a novel substrate of rho-associated kinase. Biochemical and Biophysical Research Communications. 278: 72-8. PMID 11071857 DOI: 10.1006/Bbrc.2000.3772  0.45
2000 Amano M, Fukata Y, Shimokawa H, Kaibuchi K. Purification and in vitro activity of Rho-associated kinase. Methods in Enzymology. 325: 149-55. PMID 11036600 DOI: 10.1016/S0076-6879(00)25439-6  0.443
2000 Nakamura N, Oshiro N, Fukata Y, Amano M, Fukata M, Kuroda S, Matsuura Y, Leung T, Lim L, Kaibuchi K. Phosphorylation of ERM proteins at filopodia induced by Cdc42. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 5: 571-81. PMID 10947843 DOI: 10.1046/J.1365-2443.2000.00348.X  0.457
2000 Ihara K, Shimizu T, Maesaki R, Okada K, Amano M, Kaibuchi K, Hakoshima T. Crystallization and preliminary crystallographic analysis of the Rho-binding domain of bovine Rho-kinase. Acta Crystallographica. Section D, Biological Crystallography. 56: 1042-4. PMID 10944348 DOI: 10.1107/S0907444900007174  0.39
2000 Sato M, Tani E, Fujikawa H, Kaibuchi K. Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm. Circulation Research. 87: 195-200. PMID 10926869 DOI: 10.1161/01.Res.87.3.195  0.417
2000 Hamaguchi T, Ito M, Feng J, Seko T, Koyama M, Machida H, Takase K, Amano M, Kaibuchi K, Hartshorne DJ, Nakano T. Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. Biochemical and Biophysical Research Communications. 274: 825-30. PMID 10924361 DOI: 10.1006/Bbrc.2000.3225  0.46
2000 Szászi K, Kurashima K, Kapus A, Paulsen A, Kaibuchi K, Grinstein S, Orlowski J. RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation. The Journal of Biological Chemistry. 275: 28599-606. PMID 10893221 DOI: 10.1016/S1095-6433(00)80283-4  0.433
2000 Kaneko T, Amano M, Maeda A, Goto H, Takahashi K, Ito M, Kaibuchi K. Identification of calponin as a novel substrate of Rho-kinase. Biochemical and Biophysical Research Communications. 273: 110-6. PMID 10873572 DOI: 10.1006/Bbrc.2000.2901  0.459
2000 Hashimoto R, Nakamura Y, Komai S, Kashiwagi Y, Tamura K, Goto T, Aimoto S, Kaibuchi K, Shiosaka S, Takeda M. Site-specific phosphorylation of neurofilament-L is mediated by calcium/calmodulin-dependent protein kinase II in the apical dendrites during long-term potentiation. Journal of Neurochemistry. 75: 373-82. PMID 10854283 DOI: 10.1046/J.1471-4159.2000.0750373.X  0.409
2000 Inagaki N, Nishizawa M, Arimura N, Yamamoto H, Takeuchi Y, Miyamoto E, Kaibuchi K, Inagaki M. Activation of Ca2+/calmodulin-dependent protein kinase II within post-synaptic dendritic spines of cultured hippocampal neurons. The Journal of Biological Chemistry. 275: 27165-71. PMID 10852918 DOI: 10.1074/Jbc.M003751200  0.406
2000 Eto Y, Shimokawa H, Hiroki J, Morishige K, Kandabashi T, Matsumoto Y, Amano M, Hoshijima M, Kaibuchi K, Takeshita A. Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs. American Journal of Physiology. Heart and Circulatory Physiology. 278: H1744-50. PMID 10843868 DOI: 10.1152/Ajpheart.2000.278.6.H1744  0.386
2000 Arimura N, Inagaki N, Chihara K, Ménager C, Nakamura N, Amano M, Iwamatsu A, Goshima Y, Kaibuchi K. Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse. The Journal of Biological Chemistry. 275: 23973-80. PMID 10818093 DOI: 10.1074/Jbc.M001032200  0.464
2000 Royal I, Lamarche-Vane N, Lamorte L, Kaibuchi K, Park M. Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation. Molecular Biology of the Cell. 11: 1709-25. PMID 10793146 DOI: 10.1091/Mbc.11.5.1709  0.472
2000 Oude Weernink PA, Schulte P, Guo Y, Wetzel J, Amano M, Kaibuchi K, Haverland S, Voss M, Schmidt M, Mayr GW, Jakobs KH. Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase. The Journal of Biological Chemistry. 275: 10168-74. PMID 10744700 DOI: 10.1074/Jbc.275.14.10168  0.447
2000 Kandabashi T, Shimokawa H, Miyata K, Kunihiro I, Kawano Y, Fukata Y, Higo T, Egashira K, Takahashi S, Kaibuchi K, Takeshita A. Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta. Circulation. 101: 1319-23. PMID 10725293 DOI: 10.1161/01.Cir.101.11.1319  0.335
1999 Kaibuchi K, Kuroda S, Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annual Review of Biochemistry. 68: 459-86. PMID 10872457 DOI: 10.1146/Annurev.Biochem.68.1.459  0.35
1999 Fukata Y, Oshiro N, Kaibuchi K. Activation of moesin and adducin by Rho-kinase downstream of Rho. Biophysical Chemistry. 82: 139-47. PMID 10631797 DOI: 10.1016/S0301-4622(99)00113-1  0.481
1999 Taya S, Yamamoto T, Kanai-Azuma M, Wood SA, Kaibuchi K. The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 4: 757-67. PMID 10620020 DOI: 10.1046/J.1365-2443.1999.00297.X  0.303
1999 Maesaki R, Ihara K, Shimizu T, Kuroda S, Kaibuchi K, Hakoshima T. The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Molecular Cell. 4: 793-803. PMID 10619026 DOI: 10.1016/S1097-2765(00)80389-5  0.345
1999 Shimokawa H, Seto M, Katsumata N, Amano M, Kozai T, Yamawaki T, Kuwata K, Kandabashi T, Egashira K, Ikegaki I, Asano T, Kaibuchi K, Takeshita A. Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm. Cardiovascular Research. 43: 1029-39. PMID 10615430 DOI: 10.1016/S0008-6363(99)00144-3  0.412
1999 Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, Ito M, Matsumura F, Inagaki M, Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. The Journal of Cell Biology. 147: 1023-38. PMID 10579722 DOI: 10.1083/Jcb.147.5.1023  0.474
1999 Inada H, Togashi H, Nakamura Y, Kaibuchi K, Nagata K, Inagaki M. Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments. The Journal of Biological Chemistry. 274: 34932-9. PMID 10574968 DOI: 10.1074/Jbc.274.49.34932  0.467
1999 Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. Cell adhesion and Rho small GTPases. Journal of Cell Science. 112: 4491-500. PMID 10574699  0.3
1999 Mizuno T, Amano M, Kaibuchi K, Nishida Y. Identification and characterization of Drosophila homolog of Rho-kinase. Gene. 238: 437-44. PMID 10570971 DOI: 10.1016/S0378-1119(99)00351-0  0.446
1999 Yamamoto T, Taya S, Kaibuchi K. Ras-induced transformation and signaling pathway. Journal of Biochemistry. 126: 799-803. PMID 10544270 DOI: 10.1093/Oxfordjournals.Jbchem.A022519  0.344
1999 Amano M, Chihara K, Nakamura N, Kaneko T, Matsuura Y, Kaibuchi K. The COOH terminus of Rho-kinase negatively regulates rho-kinase activity. The Journal of Biological Chemistry. 274: 32418-24. PMID 10542285 DOI: 10.1074/Jbc.274.45.32418  0.457
1999 Kuwahara H, Araki N, Makino K, Masuko N, Honda S, Kaibuchi K, Fukunaga K, Miyamoto E, Ogawa M, Saya H. A novel NE-dlg/SAP102-associated protein, p51-nedasin, related to the amidohydrolase superfamily, interferes with the association between NE-dlg/SAP102 and N-methyl-D-aspartate receptor. The Journal of Biological Chemistry. 274: 32204-14. PMID 10542258 DOI: 10.1074/Jbc.274.45.32204  0.377
1999 Kaibuchi K, Kuroda S, Fukata M, Nakagawa M. Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases. Current Opinion in Cell Biology. 11: 591-6. PMID 10508646 DOI: 10.1016/S0955-0674(99)00014-9  0.363
1999 Hashimoto R, Nakamura Y, Kosako H, Amano M, Kaibuchi K, Inagaki M, Takeda M. Distribution of Rho-kinase in the bovine brain. Biochemical and Biophysical Research Communications. 263: 575-9. PMID 10491334 DOI: 10.1006/Bbrc.1999.1409  0.452
1999 Fukata M, Kuroda S, Nakagawa M, Kawajiri A, Itoh N, Shoji I, Matsuura Y, Yonehara S, Fujisawa H, Kikuchi A, Kaibuchi K. Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin. The Journal of Biological Chemistry. 274: 26044-50. PMID 10473551 DOI: 10.1074/Jbc.274.37.26044  0.315
1999 Kuroda S, Fukata M, Nakagawa M, Kaibuchi K. Cdc42, Rac1, and their effector IQGAP1 as molecular switches for cadherin-mediated cell-cell adhesion. Biochemical and Biophysical Research Communications. 262: 1-6. PMID 10448058 DOI: 10.1006/Bbrc.1999.1122  0.352
1999 Maesaki R, Shimizu T, Ihara K, Kuroda S, Kaibuchi K, Hakoshima T. Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA. Journal of Structural Biology. 126: 166-70. PMID 10388627 DOI: 10.1006/Jsbi.1999.4114  0.39
1999 Hoshino M, Sone M, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C. Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. The Journal of Biological Chemistry. 274: 17837-44. PMID 10364228 DOI: 10.1074/Jbc.274.25.17837  0.406
1999 Kosako H, Goto H, Yanagida M, Matsuzawa K, Fujita M, Tomono Y, Okigaki T, Odai H, Kaibuchi K, Inagaki M. Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments. Oncogene. 18: 2783-8. PMID 10348354 DOI: 10.1038/Sj.Onc.1202633  0.428
1999 Schmidt M, Voss M, Weernink PA, Wetzel J, Amano M, Kaibuchi K, Jakobs KH. A role for rho-kinase in rho-controlled phospholipase D stimulation by the m3 muscarinic acetylcholine receptor. The Journal of Biological Chemistry. 274: 14648-54. PMID 10329658 DOI: 10.1074/Jbc.274.21.14648  0.456
1999 Tsubakimoto K, Matsumoto K, Abe H, Ishii J, Amano M, Kaibuchi K, Endo T. Small GTPase RhoD suppresses cell migration and cytokinesis. Oncogene. 18: 2431-40. PMID 10229194 DOI: 10.1038/Sj.Onc.1202604  0.347
1999 Fukata Y, Oshiro N, Kinoshita N, Kawano Y, Matsuoka Y, Bennett V, Matsuura Y, Kaibuchi K. Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility. The Journal of Cell Biology. 145: 347-61. PMID 10209029 DOI: 10.1083/Jcb.145.2.347  0.416
1999 Kaibuchi K. Regulation of cytoskeleton and cell adhesion by Rho targets. Progress in Molecular and Subcellular Biology. 22: 23-38. PMID 10081063 DOI: 10.1007/978-3-642-58591-3_2  0.348
1999 Nilius B, Voets T, Prenen J, Barth H, Aktories K, Kaibuchi K, Droogmans G, Eggermont J. Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells. The Journal of Physiology. 516: 67-74. PMID 10066923 DOI: 10.1111/J.1469-7793.1999.067Aa.X  0.409
1999 Takahashi N, Tuiki H, Saya H, Kaibuchi K. Localization of the gene coding for ROCK II/Rho kinase on human chromosome 2p24. Genomics. 55: 235-7. PMID 9933571 DOI: 10.1006/Geno.1998.5344  0.317
1999 Feng J, Ito M, Kureishi Y, Ichikawa K, Amano M, Isaka N, Okawa K, Iwamatsu A, Kaibuchi K, Hartshorne DJ, Nakano T. Rho-associated kinase of chicken gizzard smooth muscle. The Journal of Biological Chemistry. 274: 3744-52. PMID 9920927 DOI: 10.1074/Jbc.274.6.3744  0.439
1998 Amano M, Fukata Y, Kaibuchi K. Regulation of Cytoskeleton and Cell Adhesions by the Small GTPase Rho and Its Targets. Trends in Cardiovascular Medicine. 8: 162-8. PMID 21235928 DOI: 10.1016/S1050-1738(97)00145-X  0.401
1998 Izawa I, Amano M, Chihara K, Yamamoto T, Kaibuchi K. Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation. Oncogene. 17: 2863-71. PMID 9879992 DOI: 10.1038/Sj.Onc.1202213  0.36
1998 Inada H, Goto H, Tanabe K, Nishi Y, Kaibuchi K, Inagaki M. Rho-associated kinase phosphorylates desmin, the myogenic intermediate filament protein, at unique amino-terminal sites. Biochemical and Biophysical Research Communications. 253: 21-5. PMID 9875213 DOI: 10.1006/Bbrc.1998.9732  0.449
1998 Oshiro N, Fukata Y, Kaibuchi K. Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. The Journal of Biological Chemistry. 273: 34663-6. PMID 9856983 DOI: 10.1074/Jbc.273.52.34663  0.461
1998 Yasui Y, Amano M, Nagata K, Inagaki N, Nakamura H, Saya H, Kaibuchi K, Inagaki M. Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments. The Journal of Cell Biology. 143: 1249-58. PMID 9832553 DOI: 10.1083/Jcb.143.5.1249  0.471
1998 Essler M, Hermann K, Amano M, Kaibuchi K, Heesemann J, Weber PC, Aepfelbacher M. Pasteurella multocida toxin increases endothelial permeability via Rho kinase and myosin light chain phosphatase. Journal of Immunology (Baltimore, Md. : 1950). 161: 5640-6. PMID 9820544  0.311
1998 Taya S, Yamamoto T, Kano K, Kawano Y, Iwamatsu A, Tsuchiya T, Tanaka K, Kanai-Azuma M, Wood SA, Mattick JS, Kaibuchi K. The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme. The Journal of Cell Biology. 142: 1053-62. PMID 9722616 DOI: 10.1083/Jcb.142.4.1053  0.317
1998 Hock B, Böhme B, Karn T, Yamamoto T, Kaibuchi K, Holtrich U, Holland S, Pawson T, Rübsamen-Waigmann H, Strebhardt K. PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 95: 9779-84. PMID 9707552 DOI: 10.1073/Pnas.95.17.9779  0.396
1998 Essler M, Amano M, Kruse HJ, Kaibuchi K, Weber PC, Aepfelbacher M. Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells. The Journal of Biological Chemistry. 273: 21867-74. PMID 9705325 DOI: 10.1074/Jbc.273.34.21867  0.388
1998 Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, Ookubo T, Izawa I, Nagase T, Nomura N, Tani H, Shoji I, Matsuura Y, Yonehara S, Kaibuchi K. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (New York, N.Y.). 281: 832-5. PMID 9694656 DOI: 10.1126/Science.281.5378.832  0.324
1998 Amano M, Chihara K, Nakamura N, Fukata Y, Yano T, Shibata M, Ikebe M, Kaibuchi K. Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 3: 177-88. PMID 9619630 DOI: 10.1046/J.1365-2443.1998.00181.X  0.429
1998 Hashimoto R, Nakamura Y, Goto H, Wada Y, Sakoda S, Kaibuchi K, Inagaki M, Takeda M. Domain- and site-specific phosphorylation of bovine NF-L by Rho-associated kinase. Biochemical and Biophysical Research Communications. 245: 407-11. PMID 9571164 DOI: 10.1006/Bbrc.1998.8446  0.384
1998 Fujioka M, Takahashi N, Odai H, Araki S, Ichikawa K, Feng J, Nakamura M, Kaibuchi K, Hartshorne DJ, Nakano T, Ito M. A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping. Genomics. 49: 59-68. PMID 9570949 DOI: 10.1006/Geno.1998.5222  0.311
1998 Goto H, Kosako H, Tanabe K, Yanagida M, Sakurai M, Amano M, Kaibuchi K, Inagaki M. Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis. The Journal of Biological Chemistry. 273: 11728-36. PMID 9565595 DOI: 10.1074/Jbc.273.19.11728  0.454
1998 Fukata Y, Kimura K, Oshiro N, Saya H, Matsuura Y, Kaibuchi K. Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. The Journal of Cell Biology. 141: 409-18. PMID 9548719 DOI: 10.1083/Jcb.141.2.409  0.481
1998 Kita Y, Kimura KD, Kobayashi M, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Nagata S, Fukui Y. Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. Journal of Cell Science. 111: 907-15. PMID 9490635  0.335
1998 Kimura K, Fukata Y, Matsuoka Y, Bennett V, Matsuura Y, Okawa K, Iwamatsu A, Kaibuchi K. Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase. The Journal of Biological Chemistry. 273: 5542-8. PMID 9488679 DOI: 10.1074/Jbc.273.10.5542  0.472
1998 Matsui T, Maeda M, Doi Y, Yonemura S, Amano M, Kaibuchi K, Tsukita S, Tsukita S. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. The Journal of Cell Biology. 140: 647-57. PMID 9456324 DOI: 10.1083/Jcb.140.3.647  0.452
1998 Kobayashi K, Kuroda S, Fukata M, Nakamura T, Nagase T, Nomura N, Matsuura Y, Yoshida-Kubomura N, Iwamatsu A, Kaibuchi K. p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase. The Journal of Biological Chemistry. 273: 291-5. PMID 9417078 DOI: 10.1074/Jbc.273.1.291  0.407
1998 Kaibuchi K. Rho-kinase regulates neurite retraction downstream of the small GTPase Rho Neuroscience Research. 31. DOI: 10.1016/S0168-0102(98)81610-6  0.446
1997 Kuroda S, Fukata M, Fujii K, Nakamura T, Izawa I, Kaibuchi K. Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases. Biochemical and Biophysical Research Communications. 240: 430-5. PMID 9388496 DOI: 10.1006/Bbrc.1997.7675  0.335
1997 Fukata M, Kuroda S, Fujii K, Nakamura T, Shoji I, Matsuura Y, Okawa K, Iwamatsu A, Kikuchi A, Kaibuchi K. Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42. The Journal of Biological Chemistry. 272: 29579-83. PMID 9368021 DOI: 10.1074/Jbc.272.47.29579  0.33
1997 Yamamoto T, Harada N, Kano K, Taya S, Canaani E, Matsuura Y, Mizoguchi A, Ide C, Kaibuchi K. The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. The Journal of Cell Biology. 139: 785-95. PMID 9348294 DOI: 10.1083/Jcb.139.3.785  0.305
1997 Chihara K, Amano M, Nakamura N, Yano T, Shibata M, Tokui T, Ichikawa H, Ikebe R, Ikebe M, Kaibuchi K. Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase. The Journal of Biological Chemistry. 272: 25121-7. PMID 9312122 DOI: 10.1074/Jbc.272.40.25121  0.426
1997 Kobayashi M, Nagata S, Kita Y, Nakatsu N, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Saitoh I, Fukui Y. Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system. The Journal of Biological Chemistry. 272: 16089-92. PMID 9195902 DOI: 10.1074/Jbc.272.26.16089  0.469
1997 Matsuzawa K, Kosako H, Inagaki N, Shibata H, Mukai H, Ono Y, Amano M, Kaibuchi K, Matsuura Y, Azuma I, Inagaki M. Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN. Biochemical and Biophysical Research Communications. 234: 621-5. PMID 9175763 DOI: 10.1006/Bbrc.1997.6669  0.442
1997 Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, Ito M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. The Journal of Biological Chemistry. 272: 12257-60. PMID 9139666 DOI: 10.1074/Jbc.272.19.12257  0.388
1997 Kosako H, Amano M, Yanagida M, Tanabe K, Nishi Y, Kaibuchi K, Inagaki M. Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase. The Journal of Biological Chemistry. 272: 10333-6. PMID 9099667 DOI: 10.1074/Jbc.272.16.10333  0.453
1997 Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y, Kaibuchi K. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science (New York, N.Y.). 275: 1308-11. PMID 9036856 DOI: 10.1126/Science.275.5304.1308  0.361
1997 Inagaki N, Nishizawa M, Ito M, Fujioka M, Nakano T, Tsujino S, Matsuzawa K, Kimura K, Kaibuchi K, Inagaki M. Myosin binding subunit of smooth muscle myosin phosphatase at the cell-cell adhesion sites in MDCK cells. Biochemical and Biophysical Research Communications. 230: 552-6. PMID 9015360 DOI: 10.1006/Bbrc.1996.5986  0.322
1997 Sone M, Hoshino M, Suzuki E, Kuroda S, Kaibuchi K, Nakagoshi H, Saigo K, Nabeshima Y, Hama C. Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers. Science (New York, N.Y.). 275: 543-7. PMID 8999801 DOI: 10.1126/Science.275.5299.543  0.386
1997 Nakai K, Suzuki Y, Kihira H, Wada H, Fujioka M, Ito M, Nakano T, Kaibuchi K, Shiku H, Nishikawa M. Regulation of Myosin Phosphatase Through Phosphorylation of the Myosin-Binding Subunit in Platelet Activation Blood. 90: 3936-3942. DOI: 10.1182/Blood.V90.10.3936  0.405
1996 Kuroda S, Fukata M, Kobayashi K, Nakafuku M, Nomura N, Iwamatsu A, Kaibuchi K. Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1 Journal of Biological Chemistry. 271: 23363-23367. PMID 8798539 DOI: 10.1074/Jbc.271.38.23363  0.421
1996 Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). The Journal of Biological Chemistry. 271: 20246-9. PMID 8702756 DOI: 10.1074/Jbc.271.34.20246  0.442
1996 Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho- kinase) Science. 273: 245-248. PMID 8662509 DOI: 10.1126/Science.273.5272.245  0.467
1996 Shibata H, Mukai H, Inagaki Y, Homma Y, Kimura K, Kaibuchi K, Narumiya S, Ono Y. Characterization of the interaction between RhoA and the amino-terminal region of PKN. Febs Letters. 385: 221-4. PMID 8647255 DOI: 10.1016/0014-5793(96)00385-7  0.313
1996 Amano M, Mukai H, Ono Y, Chihara K, Matsui T, Hamajima Y, Okawa K, Iwamatsu A, Kaibuchi K. Identification of a putative target for Rho as the serine-threonine kinase protein kinase N. Science (New York, N.Y.). 271: 648-50. PMID 8571127 DOI: 10.1126/Science.271.5249.648  0.471
1996 Gotoh T, Hattori S, Nakamura S, Kitayama H, Noda M, Takai Y, Kaibuchi K, Matsui H, Hatase O, Takahashi H. Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G. Molecular and Cellular Biology. 15: 6746-53. PMID 8524240 DOI: 10.1128/Mcb.15.12.6746  0.331
1996 Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. The Embo Journal. 15: 2208-2216. DOI: 10.1002/J.1460-2075.1996.Tb00574.X  0.468
1995 Miyazaki M, Shirataki H, Kohno H, Kaibuchi K, Tsugita A, Takai Y. Identification as beta-adducin of a protein interacting with rabphilin-3A in the presence of Ca2+ and phosphatidylserine. Biochemical and Biophysical Research Communications. 205: 460-6. PMID 7999065 DOI: 10.1006/Bbrc.1994.2688  0.35
1995 Kuroda S, Shimizu K, Yamamori B, Matsuda S, Imazumi K, Kaibuchi K, Takai Y. Purification and characterization of REKS from Xenopus eggs. Identification of REKS as a Ras-dependent mitogen-activated protein kinase kinase kinase. The Journal of Biological Chemistry. 270: 2460-5. PMID 7852306 DOI: 10.1074/Jbc.270.6.2460  0.349
1995 Miyazaki M, Kaibuchi K, Shirataki H, Kohno H, Ueyama T, Nishikawa J, Takai Y. Rabphilin-3A binds to a M(r) 115,000 polypeptide in a phosphatidylserine- and Ca(2+)-dependent manner. Brain Research. Molecular Brain Research. 28: 29-36. PMID 7707875 DOI: 10.1016/0169-328X(94)00180-M  0.317
1995 Takai Y, Kaibuchi K, Kikuchi A, Sasaki T. Effects of prenyl modifications on interactions of small G proteins with regulators. Methods in Enzymology. 250: 122-33. PMID 7651145 DOI: 10.1016/0076-6879(95)50067-7  0.337
1994 Nakanishi H, Orita S, Kaibuchi K, Miura K, Miki H, Takenawa T, Takai Y. Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein. Biochemical and Biophysical Research Communications. 198: 1255-61. PMID 8117282 DOI: 10.1006/Bbrc.1994.1177  0.335
1994 Kim YS, Hong KS, Seong YS, Park JB, Kuroda S, Kishi K, Kaibuchi K, Takai Y. Phosphorylation and activation of mitogen-activated protein kinase by kainic acid-induced seizure in rat hippocampus. Biochemical and Biophysical Research Communications. 202: 1163-8. PMID 7519421 DOI: 10.1006/Bbrc.1994.2050  0.394
1993 Shirataki H, Kaibuchi K, Sakoda T, Kishida S, Yamaguchi T, Wada K, Miyazaki M, Takai Y. Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin. Molecular and Cellular Biology. 13: 2061-8. PMID 8384302 DOI: 10.1128/Mcb.13.4.2061  0.328
1993 Itoh T, Kaibuchi K, Masuda T, Yamamoto T, Matsuura Y, Maeda A, Shimizu K, Takai Y. A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase. Proceedings of the National Academy of Sciences of the United States of America. 90: 975-9. PMID 8381539 DOI: 10.1073/Pnas.90.3.975  0.419
1993 Garrett MD, Kabcenell AK, Zahner JE, Kaibuchi K, Sasaki T, Takai Y, Cheney CM, Novick PJ. Interaction of Sec4 with GDI proteins from bovine brain, Drosophila melanogaster and Saccharomyces cerevisiae. Conservation of GDI membrane dissociation activity. Febs Letters. 331: 233-8. PMID 8375508 DOI: 10.1016/0014-5793(93)80343-S  0.301
1993 Takai Y, Kaibuchi K, Kikuchi A, Sasaki T. GDP/GTP Exchange Proteins for Small GTP-Binding Proteins Handbook of Experimental Pharmacology. 108: 613-624. DOI: 10.1007/978-3-642-78267-1_39  0.326
1992 Hiraoka K, Kaibuchi K, Ando S, Musha T, Takaishi K, Mizuno T, Asada M, Ménard L, Tomhave E, Didsbury J. Both stimulatory and inhibitory GDP/GTP exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins. Biochemical and Biophysical Research Communications. 182: 921-30. PMID 1734890 DOI: 10.1016/0006-291X(92)91820-G  0.329
1992 Takai Y, Kaibuchi K, Kikuchi A, Kawata M. Small GTP-binding proteins. International Review of Cytology. 133: 187-230. PMID 1577587 DOI: 10.1016/S0074-7696(08)61861-6  0.303
1992 Miura Y, Kaibuchi K, Itoh T, Corbin JD, Francis SH, Takai Y. Phosphorylation of smg p21B/rap1B p21 by cyclic GMP-dependent protein kinase Febs Letters. 297: 171-174. PMID 1551424 DOI: 10.1016/0014-5793(92)80353-I  0.449
1992 Muramatsu M, Kaibuchi K, Arai K. Protein kinase C mutants in the auto-inhibitory region exhibit two distinct properties. Febs Letters. 311: 75-9. PMID 1397296 DOI: 10.1016/0014-5793(92)81371-R  0.473
1991 Mizuno T, Kaibuchi K, Yamamoto T, Kawamura M, Sakoda T, Fujioka H, Matsuura Y, Takai Y. A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. Proceedings of the National Academy of Sciences of the United States of America. 88: 6442-6. PMID 1907371 DOI: 10.1073/Pnas.88.15.6442  0.303
1991 Itoh T, Kaibuchi K, Sasaki T, Takai Y. The smg GDS-induced activation of smg p21 is initiated by cyclic AMP-dependent protein kinase-catalyzed phosphorylation of smg p21. Biochemical and Biophysical Research Communications. 177: 1319-24. PMID 1905539 DOI: 10.1016/0006-291X(91)90685-Z  0.455
1991 Sasaki T, Kaibuchi K, Kabcenell AK, Novick PJ, Takai Y. A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein. Molecular and Cellular Biology. 11: 2909-12. PMID 1901952 DOI: 10.1128/Mcb.11.5.2909  0.396
1991 Kaibuchi K, Mizuno T, Fujioka H, Yamamoto T, Kishi K, Fukumoto Y, Hori Y, Takai Y. Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. Molecular and Cellular Biology. 11: 2873-80. PMID 1901951 DOI: 10.1128/Mcb.11.5.2873  0.326
1991 Shimizu K, Kaibuchi K, Nonaka H, Yamamoto J, Takai Y. Tissue and subcellular distributions of an inhibitory GDP/GTP exchange protein (GDI) for the rho proteins by use of its specific antibody. Biochemical and Biophysical Research Communications. 175: 199-206. PMID 1900152 DOI: 10.1016/S0006-291X(05)81220-3  0.326
1991 Kawamura S, Kaibuchi K, Hiroyoshi M, Hata Y, Takai Y. Stoichiometric interaction of smg p21 with its GDP/GTP exchange protein and its novel action to regulate the translocation of smg p21 between membrane and cytoplasm. Biochemical and Biophysical Research Communications. 174: 1095-102. PMID 1900001 DOI: 10.1016/0006-291X(91)91533-I  0.305
1991 Araki S, Kaibuchi K, Sasaki T, Hata Y, Takai Y. Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein. Molecular and Cellular Biology. 11: 1438-47. PMID 1899908 DOI: 10.1128/Mcb.11.3.1438  0.322
1991 Nonaka H, Kaibuchi K, Shimizu K, Yamamoto J, Takai Y. Tissue and subcellular distributions of an inhibitory GDP/GTP exchange protein (GDI) for smg p25A by use of its antibody. Biochemical and Biophysical Research Communications. 174: 556-63. PMID 1899568 DOI: 10.1016/0006-291X(91)91453-J  0.31
1991 Fujimoto A, Kai S, Akiyama T, Toyoshima K, Kaibuchi K, Takai Y, Yamamoto T. Transactivation of the TPA-responsive element by the oncogenic C-erbB-2 protein is partly mediated by protein kinase C. Biochemical and Biophysical Research Communications. 178: 724-32. PMID 1677566 DOI: 10.1016/0006-291X(91)90168-7  0.39
1990 Oku N, Kaibuchi K, Fukumoto Y, Hori Y, Fujioka H, Takai Y. Comparison of the mode of action of ras p21 with those of protein kinases A and C in the stimulation of gene expression in NIH/3T3 cells. Febs Letters. 269: 148-52. PMID 2117552 DOI: 10.1016/0014-5793(90)81141-A  0.369
1990 Isomura M, Kaibuchi K, Yamamoto T, Kawamura S, Katayama M, Takai Y. Partial purification and characterization of GDP dissociation stimulator (GDS) for the rho proteins from bovine brain cytosol. Biochemical and Biophysical Research Communications. 169: 652-9. PMID 2113382 DOI: 10.1016/0006-291X(90)90380-6  0.359
1988 Matsumoto K, Nakafuku M, Nakayama N, Miyajima I, Kaibuchi K, Miyajima A, Brenner C, Arai K, Kaziro Y. The role of G proteins in yeast signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 567-575. PMID 2855496 DOI: 10.1101/Sqb.1988.053.01.065  0.31
1987 Miyajima I, Nakafuku M, Nakayama N, Brenner C, Miyajima A, Kaibuchi K, Arai Ki, Kaziro Y, Matsumoto K. GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction Cell. 50: 1011-1019. PMID 3113739 DOI: 10.1016/0092-8674(87)90167-X  0.362
1987 Tsuda T, Hamamori Y, Fukumoto Y, Kaibuchi K, Takai Y. Epidermal growth factor increases c-myc mRNA without eliciting phosphoinositide turnover, protein kinase C activation, or calcium ion mobilization in Swiss 3T3 fibroblasts. Journal of Biochemistry. 100: 1631-5. PMID 3032920 DOI: 10.1093/Oxfordjournals.Jbchem.A121871  0.359
1986 Takai Y, Kaibuchi K, Tsuda T, Hoshijima M. Role of protein kinase C in transmembrane signaling. Journal of Cellular Biochemistry. 29: 143-55. PMID 4066778 DOI: 10.1002/Jcb.240290209  0.437
1986 Takeyama Y, Tanimoto T, Hoshijima M, Kaibuchi K, Ohyanagi H, Saitoh Y, Takai Y. Enhancement of fibroblast growth factor-induced diacylglycerol formation and protein kinase C activation by colon tumor-promoting bile acid in Swiss 3T3 cells. Different modes of action between bile acid and phorbol ester. Febs Letters. 197: 339-43. PMID 3949019 DOI: 10.1016/0014-5793(86)80353-2  0.427
1986 Katakami Y, Nakao Y, Matsui T, Koizumi T, Kaibuchi K, Takai Y, Fujita T. Possible involvement of protein kinase C in interleukin-1 production by mouse peritoneal macrophages. Biochemical and Biophysical Research Communications. 135: 355-62. PMID 3083809 DOI: 10.1016/0006-291X(86)90002-1  0.352
1986 Kawahara Y, Fukuzaki H, Kaibuchi K, Tsuda T, Hoshijima M, Takai Y. Activation of protein kinase C by the action of 9,11-epithio-11,12-methano-thromboxane A2 (STA2), a stable analogue of thromboxane A2, in human platelets. Thrombosis Research. 41: 811-8. PMID 3010491 DOI: 10.1016/0049-3848(86)90379-8  0.433
1986 Takeyama Y, Nakanishi H, Ohyanagi H, Saitoh Y, Kaibuchi K, Takai Y. Enhancement of secretagogue-induced phosphoinositide turnover and amylase secretion by bile acids in isolated rat pancreatic acini. The Journal of Clinical Investigation. 78: 1604-11. PMID 2431003 DOI: 10.1172/Jci112753  0.354
1985 Sano K, Nakamura H, Matsuo T, Kawahara Y, Fukuzaki H, Kaibuchi K, Takai Y. Comparison of the modes of action of Ca2+ ionophore A23187 and thrombin in protein kinase C activation in human platelets. Febs Letters. 192: 4-8. PMID 3932095 DOI: 10.1016/0014-5793(85)80031-4  0.404
1985 Kaibuchi K, Takai Y, Nishizuka Y. Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes. The Journal of Biological Chemistry. 260: 1366-9. PMID 3155734  0.559
1985 Tsuda T, Kaibuchi K, Kawahara Y, Fukuzaki H, Takai Y. Induction of protein kinase C activation and Ca2+ mobilization by fibroblast growth factor in Swiss 3T3 cells. Febs Letters. 191: 205-10. PMID 2996931 DOI: 10.1016/0014-5793(85)80009-0  0.387
1984 Kikkawa U, Kaibuchi K, Castagna M, Yamanishi J, Sano K, Tanaka Y, Miyake R, Takai Y, Nishizuka Y. Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 437-42. PMID 6328930  0.559
1984 Miyake R, Tanaka Y, Tsuda T, Kaibuchi K, Kikkawa U, Nishizuka Y. Activation of protein kinase C by non-phorbol tumor promoter, mezerein. Biochemical and Biophysical Research Communications. 121: 649-56. PMID 6233978 DOI: 10.1016/0006-291X(84)90231-6  0.592
1984 Katakami Y, Kaibuchi K, Sawamura M, Takai Y, Nishizuka Y. Synergistic action of protein kinase C and calcium for histamine release from rat peritoneal mast cells. Biochemical and Biophysical Research Communications. 121: 573-8. PMID 6203533 DOI: 10.1016/0006-291X(84)90220-1  0.625
1984 Takai Y, Kikkawa U, Kaibuchi K, Nishizuka Y. Membrane phospholipid metabolism and signal transduction for protein phosphorylation. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 18: 119-58. PMID 6093478  0.504
1984 Nishizuka Y, Takai Y, Kishimoto A, Kikkawa U, Kaibuchi K. Phospholipid turnover in hormone action. Recent Progress in Hormone Research. 40: 301-45. PMID 6091193 DOI: 10.1016/B978-0-12-571140-1.50012-8  0.575
1983 Kaibuchi K, Takai Y, Sawamura M, Hoshijima M, Fujikura T, Nishizuka Y. Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation. The Journal of Biological Chemistry. 258: 6701-4. PMID 6406488  0.588
1983 Yamanishi J, Takai Y, Kaibuchi K, Sano K, Castagna M, Nishizuka Y. Synergistic functions of phorbol ester and calcium in serotonin release from human platelets. Biochemical and Biophysical Research Communications. 112: 778-86. PMID 6405748 DOI: 10.1016/0006-291X(83)91529-2  0.599
1983 Kajikawa N, Kaibuchi K, Matsubara T, Kikkawa U, Takai Y, Nishizuka Y, Itoh K, Tomioka C. A possible role of protein kinase C in signal-induced lysosomal enzyme release. Biochemical and Biophysical Research Communications. 116: 743-50. PMID 6228230 DOI: 10.1016/0006-291X(83)90587-9  0.578
1982 Ieyasu H, Takai Y, Kaibuchi K, Sawamura M, Nishizuka Y. A role of calcium-activated, phospholipid-dependent protein kinase in platelet-activating factor-induced serotonin release from rabbit platelets. Biochemical and Biophysical Research Communications. 108: 1701-8. PMID 7181916 DOI: 10.1016/S0006-291X(82)80107-1  0.624
1982 Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. The Journal of Biological Chemistry. 257: 7847-51. PMID 7085651  0.582
1982 Takai Y, Minakuchi R, Kikkawa U, Sano K, Kaibuchi K, Yu B, Matsubara T, Nishizuka Y. Membrane phospholipid turnover, receptor function and protein phosphorylation. Progress in Brain Research. 56: 287-301. PMID 6298874 DOI: 10.1016/S0079-6123(08)63780-2  0.544
1982 Kaibuchi K, Takai Y, Ogawa Y, Kimura S, Nishizuka Y, Nakamura T, Tomomura A, Ichihara A. Inhibitory action of adenosine 3',5'-monophosphate on phosphatidylinositol turnover: difference in tissue response. Biochemical and Biophysical Research Communications. 104: 105-12. PMID 6280686 DOI: 10.1016/0006-291X(82)91946-5  0.558
1982 Takai Y, Kaibuchi K, Sano K, Nishizuka Y. Counteraction of calcium-activated, phospholipid-dependent protein kinase activation by adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in platelets. Journal of Biochemistry. 91: 403-6. PMID 6279587 DOI: 10.1093/Oxfordjournals.Jbchem.A133700  0.617
1982 Kaibuchi K, Sano K, Hoshijima M, Takai Y, Nishizuka Y. Phosphatidylinositol turnover in platelet activation; calcium mobilization and protein phosphorylation. Cell Calcium. 3: 323-35. PMID 6218878 DOI: 10.1016/0143-4160(82)90020-3  0.604
1981 Takai Y, Kishimoto A, Kawahara Y, Minakuchi R, Sano K, Kikkawa U, Mori T, Yu B, Kaibuchi K, Nishizuka Y. Calcium and phosphatidylinositol turnover as signalling for transmembrane control of protein phosphorylation. Advances in Cyclic Nucleotide Research. 14: 301-13. PMID 7282484  0.51
1981 Kaibuchi K, Takai Y, Nishizuka Y. Cooperative roles of various membrane phospholipids in the activation of calcium-activated, phospholipid-dependent protein kinase. The Journal of Biological Chemistry. 256: 7146-9. PMID 7251589  0.517
1981 Takai Y, Kaibuchi K, Matsubara T, Nishizuka Y. Inhibitory action of guanosine 3', 5'-monophosphate on thrombin-induced phosphatidylinositol turnover and protein phosphorylation in human platelets. Biochemical and Biophysical Research Communications. 101: 61-7. PMID 6269550 DOI: 10.1016/S0006-291X(81)80010-1  0.586
1981 KAWAHARA Y, SANO K, MINAKUCHI R, KIKKAWA U, YU B, MORI T, KAIBUCHI K, TAKAHASHI J, TAKAI Y, NISHIZUKA Y. Blood & Vessel. 12: 532-540. DOI: 10.2491/Jjsth1970.12.532  0.502
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