Kozo Kaibuchi - Publications

Affiliations: 
Nagoya University Graduate School of Medicine, Nagoya-shi, Aichi-ken, Japan 

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ariza A, Funahashi Y, Kozawa S, Omar Faruk M, Nagai T, Amano M, Kaibuchi K. Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK. Journal of Neurochemistry. PMID 33449379 DOI: 10.1111/jnc.15303  0.767
2020 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, ... Kaibuchi K, et al. DSCAM regulates delamination of neurons in the developing midbrain. Science Advances. 6. PMID 32917586 DOI: 10.1126/Sciadv.Aba1693  0.317
2020 Sekiguchi M, Sobue A, Kushima I, Wang C, Arioka Y, Kato H, Kodama A, Kubo H, Ito N, Sawahata M, Hada K, Ikeda R, Shinno M, Mizukoshi C, Tsujimura K, ... ... Kaibuchi K, et al. ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk. Translational Psychiatry. 10: 247. PMID 32699248 DOI: 10.1038/S41398-020-00917-Z  0.354
2020 Ikezu S, Ingraham Dixie KL, Koro L, Watanabe T, Kaibuchi K, Ikezu T. Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models. Acta Neuropathologica Communications. 8: 12. PMID 32019603 DOI: 10.1186/S40478-020-0890-4  0.351
2019 Funahashi Y, Ariza A, Emi R, Xu Y, Shan W, Suzuki K, Kozawa S, Ahammad RU, Wu M, Takano T, Yura Y, Kuroda K, Nagai T, Amano M, Yamada K, ... Kaibuchi K, et al. Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. Cell Reports. 29: 3235-3252.e9. PMID 31801086 DOI: 10.1016/J.Celrep.2019.10.116  0.765
2019 Nishino T, Tamada K, Maeda A, Abe T, Kiyonari H, Funahashi Y, Kaibuchi K, Takumi T, Konishi H. Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain. Molecular Brain. 12: 94. PMID 31718706 DOI: 10.1186/S13041-019-0512-X  0.341
2019 Ogino K, Yamada K, Nishioka T, Oda Y, Kaibuchi K, Hirata H. Phosphorylation of gephyrin in zebrafish Mauthner cells governs glycine receptor clustering and behavioral desensitization to sound. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31558619 DOI: 10.1523/Jneurosci.1315-19.2019  0.318
2019 Hanafusa H, Yagi T, Ikeda H, Hisamoto N, Nishioka T, Kaibuchi K, Shirakabe K, Matsumoto K. LRRK1 phosphorylation of Rab7 at Ser-72 links trafficking of EGFR-containing endosomes to its effector RILP. Journal of Cell Science. PMID 31085713 DOI: 10.1242/Jcs.228809  0.359
2018 Zhang X, Nagai T, Ahammad RU, Kuroda K, Nakamuta S, Nakano T, Yukinawa N, Funahashi Y, Yamahashi Y, Amano M, Yoshimoto J, Yamada K, Kaibuchi K. Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons. Neurochemistry International. PMID 30336179 DOI: 10.1016/J.Neuint.2018.10.008  0.353
2017 Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K. Discovery of long-range inhibitory signaling to ensure single axon formation. Nature Communications. 8: 33. PMID 28652571 DOI: 10.1038/S41467-017-00044-2  0.353
2016 Li C, Imanishi A, Komatsu N, Terai K, Amano M, Kaibuchi K, Matsuda M. A FRET biosensor for ROCK based on a consensus substrate sequence identified by KISS technology. Cell Structure and Function. PMID 27885213 DOI: 10.1247/Csf.16016  0.33
2016 Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, Fujisawa H, Iwata N, Suga H, Watanabe T, Kaibuchi K, Oiso Y, Arima H, Sugimura Y. Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons. Plos One. 11: e0164544. PMID 27732637 DOI: 10.1371/Journal.Pone.0164544  0.348
2016 Nagai T, Yoshimoto J, Kannon T, Kuroda K, Kaibuchi K. Phosphorylation Signals in Striatal Medium Spiny Neurons. Trends in Pharmacological Sciences. PMID 27546785 DOI: 10.1016/J.Tips.2016.07.003  0.337
2016 Kobayashi K, Sano H, Kato S, Kuroda K, Nakamuta S, Isa T, Nambu A, Kaibuchi K, Kobayashi K. Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway. Neuroscience Letters. PMID 27424794 DOI: 10.1016/J.Neulet.2016.07.020  0.345
2016 Yura Y, Amano M, Takefuji M, Bando T, Suzuki K, Kato K, Hamaguchi T, Shohag MH, Takano T, Funahashi Y, Nakamuta S, Kuroda K, Nishioka T, Murohara T, Kaibuchi K. Focused proteomics revealed a novel Rho-kinase signaling pathway in the heart. Cell Structure and Function. PMID 27334702 DOI: 10.1247/Csf.16011  0.385
2016 Matsuzawa K, Akita H, Watanabe T, Kakeno M, Matsui T, Wang S, Kaibuchi K. PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions. Molecular Biology of the Cell. PMID 26941335 DOI: 10.1091/Mbc.E15-09-0670  0.359
2016 Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, ... ... Kaibuchi K, et al. Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo. Neuron. PMID 26804993 DOI: 10.1016/J.Neuron.2015.12.019  0.35
2015 Yamaoka M, Ando T, Terabayashi T, Okamoto M, Takei M, Nishioka T, Kaibuchi K, Matsunaga K, Ishizaki R, Izumi T, Niki I, Ishizaki T, Kimura T. PI3K regulates endocytosis after insulin secretion via signaling crosstalk between Arf6 and Rab27a. Journal of Cell Science. PMID 26683831 DOI: 10.1242/Jcs.180141  0.337
2015 Amano M, Hamaguchi T, Shohag MH, Kozawa K, Kato K, Zhang X, Yura Y, Matsuura Y, Kataoka C, Nishioka T, Kaibuchi K. Kinase-interacting substrate screening is a novel method to identify kinase substrates. The Journal of Cell Biology. 209: 895-912. PMID 26101221 DOI: 10.1083/Jcb.201412008  0.373
2015 Watanabe T, Wang S, Kaibuchi K. IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics. Cell Structure and Function. 40: 69-77. PMID 26051604 DOI: 10.1247/Csf.15003  0.328
2015 Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, Shinoda T, Hikita T, Muraoka S, Iizuka M, Nimura A, Mizoguchi A, Shiina N, Sokabe M, Okano H, ... ... Kaibuchi K, et al. Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nature Neuroscience. 18: 698-707. PMID 25821909 DOI: 10.1038/Nn.3984  0.48
2015 Kedashiro S, Pastuhov SI, Nishioka T, Watanabe T, Kaibuchi K, Matsumoto K, Hanafusa H. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. Journal of Cell Science. 128: 829. PMID 25681495 DOI: 10.1242/Jcs.169102  0.357
2015 Matsui T, Watanabe T, Matsuzawa K, Kakeno M, Okumura N, Sugiyama I, Itoh N, Kaibuchi K. PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity. Molecular Biology of the Cell. 26: 751-61. PMID 25518939 DOI: 10.1091/Mbc.E14-09-1382  0.343
2015 Kedashiro S, Pastuhov SI, Nishioka T, Watanabe T, Kaibuchi K, Matsumoto K, Hanafusa H. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. Journal of Cell Science. 128: 385-96. PMID 25413345 DOI: 10.1242/Jcs.161547  0.356
2014 Hori K, Nagai T, Shan W, Sakamoto A, Taya S, Hashimoto R, Hayashi T, Abe M, Yamazaki M, Nakao K, Nishioka T, Sakimura K, Yamada K, Kaibuchi K, Hoshino M. Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. Cell Reports. 9: 2166-79. PMID 25533347 DOI: 10.1016/J.Celrep.2014.11.045  0.323
2014 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12168-81. PMID 25186760 DOI: 10.1523/Jneurosci.2513-13.2014  0.341
2014 Ota H, Hikita T, Sawada M, Nishioka T, Matsumoto M, Komura M, Ohno A, Kamiya Y, Miyamoto T, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K. Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA. Nature Communications. 5: 4532. PMID 25074242 DOI: 10.1038/Ncomms5532  0.305
2014 Weng L, Enomoto A, Miyoshi H, Takahashi K, Asai N, Morone N, Jiang P, An J, Kato T, Kuroda K, Watanabe T, Asai M, Ishida-Takagishi M, Murakumo Y, Nakashima H, ... Kaibuchi K, et al. Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin. The Embo Journal. 33: 2098-112. PMID 25061227 DOI: 10.15252/Embj.201488289  0.356
2014 Namba T, Kibe Y, Funahashi Y, Nakamuta S, Takano T, Ueno T, Shimada A, Kozawa S, Okamoto M, Shimoda Y, Oda K, Wada Y, Masuda T, Sakakibara A, Igarashi M, ... ... Kaibuchi K, et al. Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron. 81: 814-29. PMID 24559674 DOI: 10.1016/J.Neuron.2013.12.015  0.307
2014 Kakeno M, Matsuzawa K, Matsui T, Akita H, Sugiyama I, Ishidate F, Nakano A, Takashima S, Goto H, Inagaki M, Kaibuchi K, Watanabe T. Plk1 phosphorylates CLIP-170 and regulates its binding to microtubules for chromosome alignment. Cell Structure and Function. 39: 45-59. PMID 24451569 DOI: 10.1247/Csf.14001  0.381
2013 Ota H, Hikita T, Nishioka T, Matsumoto M, Ito J, Asai N, Enomoto A, Takahashi M, Kaibuchi K, Sobue K, Sawamoto K. Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain. Biochemical and Biophysical Research Communications. 442: 16-21. PMID 24211587 DOI: 10.1016/J.Bbrc.2013.10.126  0.328
2013 Kimura T, Yamaoka M, Taniguchi S, Okamoto M, Takei M, Ando T, Iwamatsu A, Watanabe T, Kaibuchi K, Ishizaki T, Niki I. Activated Cdc42-bound IQGAP1 determines the cellular endocytic site. Molecular and Cellular Biology. 33: 4834-43. PMID 24100016 DOI: 10.1128/Mcb.00895-13  0.312
2013 Funahashi Y, Namba T, Fujisue S, Itoh N, Nakamuta S, Kato K, Shimada A, Xu C, Shan W, Nishioka T, Kaibuchi K. ERK2-mediated phosphorylation of Par3 regulates neuronal polarization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13270-85. PMID 23946386 DOI: 10.1523/Jneurosci.4210-12.2013  0.358
2013 Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano S, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 61: 679-93. PMID 23382131 DOI: 10.1002/Glia.22461  0.301
2013 Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nature Cell Biology. 15: 249-60. PMID 23354168 DOI: 10.1038/Ncb2679  0.323
2013 Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, Yamada K. Neuronal Per Arnt Sim (PAS) domain protein 4 (NPAS4) regulates neurite outgrowth and phosphorylation of synapsin I. The Journal of Biological Chemistry. 288: 2655-64. PMID 23172225 DOI: 10.1074/Jbc.M112.413310  0.367
2012 Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration. The Journal of Cell Biology. 199: 331-45. PMID 23071154 DOI: 10.1083/Jcb.201202041  0.343
2012 Iizuka M, Kimura K, Wang S, Kato K, Amano M, Kaibuchi K, Mizoguchi A. Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues. Cell Structure and Function. 37: 155-75. PMID 22986902 DOI: 10.1247/Csf.12018  0.316
2012 Ishida-Takagishi M, Enomoto A, Asai N, Ushida K, Watanabe T, Hashimoto T, Kato T, Weng L, Matsumoto S, Asai M, Murakumo Y, Kaibuchi K, Kikuchi A, Takahashi M. The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nature Communications. 3: 859. PMID 22643886 DOI: 10.1038/Ncomms1861  0.352
2012 Chiyoda T, Sugiyama N, Shimizu T, Naoe H, Kobayashi Y, Ishizawa J, Arima Y, Tsuda H, Ito M, Kaibuchi K, Aoki D, Ishihama Y, Saya H, Kuninaka S. LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. The Journal of Cell Biology. 197: 625-41. PMID 22641346 DOI: 10.1083/Jcb.201110110  0.372
2012 Kato K, Yazawa T, Taki K, Mori K, Wang S, Nishioka T, Hamaguchi T, Itoh T, Takenawa T, Kataoka C, Matsuura Y, Amano M, Murohara T, Kaibuchi K. The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration. Molecular Biology of the Cell. 23: 2593-604. PMID 22593208 DOI: 10.1091/Mbc.E11-11-0958  0.316
2012 Ohara K, Enomoto A, Kato T, Hashimoto T, Isotani-Sakakibara M, Asai N, Ishida-Takagishi M, Weng L, Nakayama M, Watanabe T, Kato K, Kaibuchi K, Murakumo Y, Hirooka Y, Goto H, et al. Involvement of Girdin in the determination of cell polarity during cell migration. Plos One. 7: e36681. PMID 22574214 DOI: 10.1371/Journal.Pone.0036681  0.34
2012 Okada M, Hozumi Y, Iwazaki K, Misaki K, Yanagida M, Araki Y, Watanabe T, Yagisawa H, Topham MK, Kaibuchi K, Goto K. DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway. Biochemical and Biophysical Research Communications. 420: 479-84. PMID 22450320 DOI: 10.1016/J.Bbrc.2012.03.057  0.327
2011 Nakamuta S, Funahashi Y, Namba T, Arimura N, Picciotto MR, Tokumitsu H, Soderling TR, Sakakibara A, Miyata T, Kamiguchi H, Kaibuchi K. Local application of neurotrophins specifies axons through inositol 1,4,5-trisphosphate, calcium, and Ca2+/calmodulin-dependent protein kinases. Science Signaling. 4: ra76. PMID 22087032 DOI: 10.1126/Scisignal.2002011  0.311
2011 Kuroda K, Yamada S, Tanaka M, Iizuka M, Yano H, Mori D, Tsuboi D, Nishioka T, Namba T, Iizuka Y, Kubota S, Nagai T, Ibi D, Wang R, Enomoto A, ... ... Kaibuchi K, et al. Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Human Molecular Genetics. 20: 4666-83. PMID 21903668 DOI: 10.1093/Hmg/Ddr400  0.486
2011 Sato K, Watanabe T, Wang S, Kakeno M, Matsuzawa K, Matsui T, Yokoi K, Murase K, Sugiyama I, Ozawa M, Kaibuchi K. Numb controls E-cadherin endocytosis through p120 catenin with aPKC. Molecular Biology of the Cell. 22: 3103-19. PMID 21775625 DOI: 10.1091/Mbc.E11-03-0274  0.302
2011 Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, et al. Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8109-22. PMID 21632933 DOI: 10.1523/Jneurosci.1130-11.2011  0.332
2011 Morinaka A, Yamada M, Itofusa R, Funato Y, Yoshimura Y, Nakamura F, Yoshimura T, Kaibuchi K, Goshima Y, Hoshino M, Kamiguchi H, Miki H. Thioredoxin mediates oxidation-dependent phosphorylation of CRMP2 and growth cone collapse. Science Signaling. 4: ra26. PMID 21521879 DOI: 10.1126/Scisignal.2001127  0.321
2011 Routray C, Liu C, Yaqoob U, Billadeau DD, Bloch KD, Kaibuchi K, Shah VH, Kang N. Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes. American Journal of Physiology. Cell Physiology. 301: C66-74. PMID 21451103 DOI: 10.1152/Ajpcell.00038.2011  0.393
2011 Qadota H, Miyauchi T, Nahabedian JF, Stirman JN, Lu H, Amano M, Benian GM, Kaibuchi K. PKN-1, a homologue of mammalian PKN, is involved in the regulation of muscle contraction and force transmission in C. elegans. Journal of Molecular Biology. 407: 222-31. PMID 21277858 DOI: 10.1016/J.Jmb.2011.01.039  0.325
2011 Kobayashi K, Masuda T, Takahashi M, Miyazaki J, Nakagawa M, Uchigashima M, Watanabe M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons. The European Journal of Neuroscience. 33: 612-21. PMID 21219475 DOI: 10.1111/J.1460-9568.2010.07554.X  0.329
2011 Tsuboi D, Iizuka Y, Taya S, Shiina N, Okano H, Mikoshiba K, Kaibuchi K. Disrupted-in-Schizoprenia-1 regulates transport of neuronal mRNA for neural plasticity Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1412  0.476
2011 Iizuka Y, Kinoshita T, Tsuboi D, Mori D, Kuroda K, Kaibuchi K. Proteomic analysis reveals novel binging partner of DISC1, a candidate risk gene of schizophrenia Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1308  0.45
2010 Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, Asano Y, Seguchi O, Higo S, Shintani Y, Asanuma H, Asakura M, Minamino T, Kaibuchi K, Mochizuki N, Kitakaze M, et al. AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nature Cell Biology. 12: 583-90. PMID 20495555 DOI: 10.1038/Ncb2060  0.391
2010 Matsumoto S, Fumoto K, Okamoto T, Kaibuchi K, Kikuchi A. Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells. The Embo Journal. 29: 1192-204. PMID 20224554 DOI: 10.1038/Emboj.2010.26  0.343
2010 Amano M, Tsumura Y, Taki K, Harada H, Mori K, Nishioka T, Kato K, Suzuki T, Nishioka Y, Iwamatsu A, Kaibuchi K. A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase. Plos One. 5: e8704. PMID 20090853 DOI: 10.1371/Journal.Pone.0008704  0.375
2010 Terawaki S, Kitano K, Mori T, Zhai Y, Higuchi Y, Itoh N, Watanabe T, Kaibuchi K, Hakoshima T. The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module. The Embo Journal. 29: 236-50. PMID 19893486 DOI: 10.1038/Emboj.2009.323  0.301
2010 Funahashi Y, Fujisue S, Ito N, Yamaguchi R, Nakamuta S, Namba T, Kaibuchi K. ERK2-mediated phosphorylation of Par3 affects axon specification by modulating its interaction with KIF3A Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2190  0.319
2009 Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, ... ... Kaibuchi K, et al. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron. 63: 774-87. PMID 19778507 DOI: 10.1016/J.Neuron.2009.08.015  0.329
2009 Watanabe T, Noritake J, Kakeno M, Matsui T, Harada T, Wang S, Itoh N, Sato K, Matsuzawa K, Iwamatsu A, Galjart N, Kaibuchi K. Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules. Journal of Cell Science. 122: 2969-79. PMID 19638411 DOI: 10.1242/Jcs.046649  0.352
2008 Sugimoto M, Inoko A, Shiromizu T, Nakayama M, Zou P, Yonemura S, Hayashi Y, Izawa I, Sasoh M, Uji Y, Kaibuchi K, Kiyono T, Inagaki M. The keratin-binding protein Albatross regulates polarization of epithelial cells. The Journal of Cell Biology. 183: 19-28. PMID 18838552 DOI: 10.1083/Jcb.200803133  0.319
2008 Iwasaki T, Katsumi A, Kiyoi H, Tanizaki R, Ishikawa Y, Ozeki K, Kobayashi M, Abe A, Matsushita T, Watanabe T, Amano M, Kojima T, Kaibuchi K, Naoe T. Prognostic implication and biological roles of RhoH in acute myeloid leukaemia. European Journal of Haematology. 81: 454-60. PMID 18691253 DOI: 10.1111/J.1600-0609.2008.01132.X  0.31
2008 Yamashiro S, Yamakita Y, Totsukawa G, Goto H, Kaibuchi K, Ito M, Hartshorne DJ, Matsumura F. Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. Developmental Cell. 14: 787-97. PMID 18477460 DOI: 10.1016/J.Devcel.2008.02.013  0.38
2008 Patrakitkomjorn S, Kobayashi D, Morikawa T, Wilson MM, Tsubota N, Irie A, Ozawa T, Aoki M, Arimura N, Kaibuchi K, Saya H, Araki N. Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2. The Journal of Biological Chemistry. 283: 9399-413. PMID 18218617 DOI: 10.1074/Jbc.M708206200  0.385
2008 Yamamoto M, Ramirez SH, Sato S, Kiyota T, Cerny RL, Kaibuchi K, Persidsky Y, Ikezu T. Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells. The American Journal of Pathology. 172: 521-33. PMID 18187566 DOI: 10.2353/Ajpath.2008.070076  0.335
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, ... ... Kaibuchi K, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024  0.385
2007 Qadota H, Mercer KB, Miller RK, Kaibuchi K, Benian GM. Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle. Molecular Biology of the Cell. 18: 4317-26. PMID 17761533 DOI: 10.1091/Mbc.E07-03-0278  0.313
2007 Yagita Y, Kitagawa K, Sasaki T, Terasaki Y, Todo K, Omura-Matsuoka E, Kaibuchi K, Hori M. Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia. Journal of Neuroscience Research. 85: 2460-9. PMID 17526023 DOI: 10.1002/Jnr.21375  0.341
2007 Takefuji M, Mori K, Morita Y, Arimura N, Nishimura T, Nakayama M, Hoshino M, Iwamatsu A, Murohara T, Kaibuchi K, Amano M. Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation. Biochemical and Biophysical Research Communications. 355: 788-94. PMID 17320046 DOI: 10.1016/J.Bbrc.2007.02.028  0.399
2007 Wang S, Watanabe T, Noritake J, Fukata M, Yoshimura T, Itoh N, Harada T, Nakagawa M, Matsuura Y, Arimura N, Kaibuchi K. IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth. Journal of Cell Science. 120: 567-77. PMID 17244649 DOI: 10.1242/Jcs.03356  0.336
2007 Kobayashi K, Masuda T, Takahashi M, Miyazaki J, Nakagawa M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Key role of Rho/Rho-kinase signaling in hindbrain motor axon patterning Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.908  0.306
2006 Maeda A, Ozaki Y, Sivakumaran S, Akiyama T, Urakubo H, Usami A, Sato M, Kaibuchi K, Kuroda S. Ca2+ -independent phospholipase A2-dependent sustained Rho-kinase activation exhibits all-or-none response. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 1071-83. PMID 16923126 DOI: 10.1111/J.1365-2443.2006.01001.X  0.378
2006 Ito Y, Oinuma I, Katoh H, Kaibuchi K, Negishi M. Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse. Embo Reports. 7: 704-9. PMID 16799460 DOI: 10.1038/Sj.Embor.7400737  0.322
2006 Mimura F, Yamagishi S, Arimura N, Fujitani M, Kubo T, Kaibuchi K, Yamashita T. Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism. The Journal of Biological Chemistry. 281: 15970-9. PMID 16595691 DOI: 10.1074/Jbc.M510934200  0.366
2006 Tanaka T, Nishimura D, Wu RC, Amano M, Iso T, Kedes L, Nishida H, Kaibuchi K, Hamamori Y. Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase. The Journal of Biological Chemistry. 281: 15320-9. PMID 16574662 DOI: 10.1074/Jbc.M510954200  0.362
2006 Persidsky Y, Heilman D, Haorah J, Zelivyanskaya M, Persidsky R, Weber GA, Shimokawa H, Kaibuchi K, Ikezu T. Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood. 107: 4770-80. PMID 16478881 DOI: 10.1182/Blood-2005-11-4721  0.329
2006 Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M. Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. Cellular Signalling. 18: 1408-16. PMID 16431080 DOI: 10.1016/J.Cellsig.2005.11.001  0.329
2006 Nishimura T, Yamaguchi T, Tokunaga A, Hara A, Hamaguchi T, Kato K, Iwamatsu A, Okano H, Kaibuchi K. Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Molecular Biology of the Cell. 17: 1273-85. PMID 16394100 DOI: 10.1091/Mbc.E05-07-0700  0.339
2006 Yoshimura T, Arimura N, Kawano Y, Kawabata S, Wang S, Kaibuchi K. Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway. Biochemical and Biophysical Research Communications. 340: 62-8. PMID 16343426 DOI: 10.1016/J.Bbrc.2005.11.147  0.361
2006 Sobue G, Takahashi M, Yoshida J, Kaibuchi K, Naoe T, Lahiri DK. Integrated molecular medicine for neuronal and neoplastic disorders Annals of the New York Academy of Sciences. 1086: xi-xii. DOI: 10.1196/Annals.1377.015  0.313
2005 Hikita T, Qadota H, Tsuboi D, Taya S, Moerman DG, Kaibuchi K. Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure. Biochemical and Biophysical Research Communications. 335: 139-45. PMID 16055082 DOI: 10.1016/J.Bbrc.2005.07.068  0.321
2005 Tamaru S, Fukuta T, Kaibuchi K, Matsuoka Y, Shiku H, Nishikawa M. Rho-kinase induces association of adducin with the cytoskeleton in platelet activation. Biochemical and Biophysical Research Communications. 332: 347-51. PMID 15910744 DOI: 10.1016/J.Bbrc.2005.04.127  0.34
2005 Noritake J, Watanabe T, Sato K, Wang S, Kaibuchi K. IQGAP1: a key regulator of adhesion and migration. Journal of Cell Science. 118: 2085-92. PMID 15890984 DOI: 10.1242/Jcs.02379  0.326
2004 Watanabe T, Wang S, Noritake J, Sato K, Fukata M, Takefuji M, Nakagawa M, Izumi N, Akiyama T, Kaibuchi K. Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Developmental Cell. 7: 871-83. PMID 15572129 DOI: 10.1016/J.Devcel.2004.10.017  0.318
2004 Nakaya Y, Kuroda S, Katagiri YT, Kaibuchi K, Takahashi Y. Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Developmental Cell. 7: 425-38. PMID 15363416 DOI: 10.1016/J.Devcel.2004.08.003  0.322
2004 Birukova AA, Smurova K, Birukov KG, Usatyuk P, Liu F, Kaibuchi K, Ricks-Cord A, Natarajan V, Alieva I, Garcia JG, Verin AD. Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms. Journal of Cellular Physiology. 201: 55-70. PMID 15281089 DOI: 10.1002/Jcp.20055  0.352
2004 Hiroki J, Shimokawa H, Higashi M, Morikawa K, Kandabashi T, Kawamura N, Kubota T, Ichiki T, Amano M, Kaibuchi K, Takeshita A. Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology. 37: 537-46. PMID 15276023 DOI: 10.1016/J.Yjmcc.2004.05.008  0.378
2004 Ren XD, Wang R, Li Q, Kahek LA, Kaibuchi K, Clark RA. Disruption of Rho signal transduction upon cell detachment. Journal of Cell Science. 117: 3511-8. PMID 15226371 DOI: 10.1242/Jcs.01205  0.394
2004 Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Tsutsui H, Kaibuchi K, Takeshita A. Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice. Circulation. 109: 2234-9. PMID 15096457 DOI: 10.1161/01.Cir.0000127939.16111.58  0.317
2004 Takami A, Iwakubo M, Okada Y, Kawata T, Odai H, Takahashi N, Shindo K, Kimura K, Tagami Y, Miyake M, Fukushima K, Inagaki M, Amano M, Kaibuchi K, Iijima H. Design and synthesis of Rho kinase inhibitors (I). Bioorganic & Medicinal Chemistry. 12: 2115-37. PMID 15080913 DOI: 10.1016/J.Bmc.2004.02.025  0.329
2004 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3480-8. PMID 15071095 DOI: 10.1523/Jneurosci.0295-04.2004  0.349
2004 Noritake J, Fukata M, Sato K, Nakagawa M, Watanabe T, Izumi N, Wang S, Fukata Y, Kaibuchi K. Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. Molecular Biology of the Cell. 15: 1065-76. PMID 14699063 DOI: 10.1091/Mbc.E03-08-0582  0.315
2004 Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Kaibuchi K, Takeshita A. Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice. Circulation Research. 94: 46-52. PMID 14615290 DOI: 10.1161/01.Res.0000107196.21335.2B  0.31
2003 Amano M, Kaneko T, Maeda A, Nakayama M, Ito M, Yamauchi T, Goto H, Fukata Y, Oshiro N, Shinohara A, Iwamatsu A, Kaibuchi K. Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase. Journal of Neurochemistry. 87: 780-90. PMID 14535960 DOI: 10.1046/J.1471-4159.2003.02054.X  0.364
2003 Becknell B, Shen T, Maghraby E, Taya S, Kaibuchi K, Caligiuri MA, Marcucci G. Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development. Cell and Tissue Research. 314: 361-6. PMID 14513355 DOI: 10.1007/S00441-003-0802-5  0.329
2003 Shimizu T, Ihara K, Maesaki R, Amano M, Kaibuchi K, Hakoshima T. Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. The Journal of Biological Chemistry. 278: 46046-51. PMID 12954645 DOI: 10.1074/Jbc.M306458200  0.37
2003 Tharaux PL, Bukoski RC, Rocha PN, Crowley SD, Ruiz P, Nataraj C, Howell DN, Kaibuchi K, Spurney RF, Coffman TM. Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 96-105. PMID 12816987 DOI: 10.4049/Jimmunol.171.1.96  0.374
2003 Su L, Hattori M, Moriyama M, Murata N, Harazaki M, Kaibuchi K, Minato N. AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1. The Journal of Biological Chemistry. 278: 15232-8. PMID 12590145 DOI: 10.1074/Jbc.M211888200  0.323
2002 Fukata M, Watanabe T, Noritake J, Nakagawa M, Yamaga M, Kuroda S, Matsuura Y, Iwamatsu A, Perez F, Kaibuchi K. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell. 109: 873-85. PMID 12110184 DOI: 10.1016/S0092-8674(02)00800-0  0.302
2001 Delon J, Kaibuchi K, Germain RN. Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity. 15: 691-701. PMID 11728332 DOI: 10.1016/S1074-7613(01)00231-X  0.363
2001 Kato M, Seki N, Sugano S, Hashimoto K, Masuho Y, Muramatsu M, Kaibuchi K, Nakafuku M. Identification of sonic hedgehog-responsive genes using cDNA microarray. Biochemical and Biophysical Research Communications. 289: 472-8. PMID 11716497 DOI: 10.1006/Bbrc.2001.5976  0.333
2001 Sato M, Tani E, Fujikawa H, Yamaura I, Arita N, Kaibuchi K. Importance of Rho-kinase-mediated phosphorylation of myosin light chain in vasospasm. Acta Neurochirurgica. Supplement. 77: 49-54. PMID 11563308 DOI: 10.1007/978-3-7091-6232-3_12  0.368
2001 Szászi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J. Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. The Journal of Biological Chemistry. 276: 40761-8. PMID 11522794 DOI: 10.1074/Jbc.M106724200  0.371
2001 Zong H, Kaibuchi K, Quilliam LA. The insert region of RhoA is essential for Rho kinase activation and cellular transformation. Molecular and Cellular Biology. 21: 5287-98. PMID 11463812 DOI: 10.1128/Mcb.21.16.5287-5298.2001  0.381
2001 Katoh K, Kano Y, Amano M, Onishi H, Kaibuchi K, Fujiwara K. Rho-kinase--mediated contraction of isolated stress fibers. The Journal of Cell Biology. 153: 569-84. PMID 11331307 DOI: 10.1083/Jcb.153.3.569  0.35
2001 Araki S, Ito M, Kureishi Y, Feng J, Machida H, Isaka N, Amano M, Kaibuchi K, Hartshorne DJ, Nakano T. Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase. Pflã¼Gers Archiv : European Journal of Physiology. 441: 596-603. PMID 11294240 DOI: 10.1007/S004240000462  0.374
2001 Fukata M, Nakagawa M, Itoh N, Kawajiri A, Yamaga M, Kuroda S, Kaibuchi K. Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering. Molecular and Cellular Biology. 21: 2165-83. PMID 11238950 DOI: 10.1128/Mcb.21.6.2165-2183.2001  0.307
2000 Miyata K, Shimokawa H, Kandabashi T, Higo T, Morishige K, Eto Y, Egashira K, Kaibuchi K, Takeshita A. Rho-kinase is involved in macrophage-mediated formation of coronary vascular lesions in pigs in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2351-8. PMID 11073837 DOI: 10.1161/01.Atv.20.11.2351  0.327
2000 Nakamura N, Oshiro N, Fukata Y, Amano M, Fukata M, Kuroda S, Matsuura Y, Leung T, Lim L, Kaibuchi K. Phosphorylation of ERM proteins at filopodia induced by Cdc42. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 5: 571-81. PMID 10947843 DOI: 10.1046/J.1365-2443.2000.00348.X  0.382
2000 Hamaguchi T, Ito M, Feng J, Seko T, Koyama M, Machida H, Takase K, Amano M, Kaibuchi K, Hartshorne DJ, Nakano T. Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. Biochemical and Biophysical Research Communications. 274: 825-30. PMID 10924361 DOI: 10.1006/Bbrc.2000.3225  0.386
2000 Szászi K, Kurashima K, Kapus A, Paulsen A, Kaibuchi K, Grinstein S, Orlowski J. RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation. The Journal of Biological Chemistry. 275: 28599-606. PMID 10893221 DOI: 10.1016/S1095-6433(00)80283-4  0.37
2000 Hashimoto R, Nakamura Y, Komai S, Kashiwagi Y, Tamura K, Goto T, Aimoto S, Kaibuchi K, Shiosaka S, Takeda M. Site-specific phosphorylation of neurofilament-L is mediated by calcium/calmodulin-dependent protein kinase II in the apical dendrites during long-term potentiation. Journal of Neurochemistry. 75: 373-82. PMID 10854283 DOI: 10.1046/J.1471-4159.2000.0750373.X  0.357
2000 Royal I, Lamarche-Vane N, Lamorte L, Kaibuchi K, Park M. Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation. Molecular Biology of the Cell. 11: 1709-25. PMID 10793146 DOI: 10.1091/Mbc.11.5.1709  0.395
2000 Kandabashi T, Shimokawa H, Miyata K, Kunihiro I, Kawano Y, Fukata Y, Higo T, Egashira K, Takahashi S, Kaibuchi K, Takeshita A. Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta. Circulation. 101: 1319-23. PMID 10725293 DOI: 10.1161/01.Cir.101.11.1319  0.304
1999 Kaibuchi K, Kuroda S, Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annual Review of Biochemistry. 68: 459-86. PMID 10872457 DOI: 10.1146/Annurev.Biochem.68.1.459  0.316
1999 Fukata Y, Oshiro N, Kaibuchi K. Activation of moesin and adducin by Rho-kinase downstream of Rho. Biophysical Chemistry. 82: 139-47. PMID 10631797 DOI: 10.1016/S0301-4622(99)00113-1  0.399
1999 Maesaki R, Ihara K, Shimizu T, Kuroda S, Kaibuchi K, Hakoshima T. The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Molecular Cell. 4: 793-803. PMID 10619026 DOI: 10.1016/S1097-2765(00)80389-5  0.319
1999 Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, Ito M, Matsumura F, Inagaki M, Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. The Journal of Cell Biology. 147: 1023-38. PMID 10579722 DOI: 10.1083/Jcb.147.5.1023  0.392
1999 Kaibuchi K, Kuroda S, Fukata M, Nakagawa M. Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases. Current Opinion in Cell Biology. 11: 591-6. PMID 10508646 DOI: 10.1016/S0955-0674(99)00014-9  0.327
1999 Fukata M, Kuroda S, Nakagawa M, Kawajiri A, Itoh N, Shoji I, Matsuura Y, Yonehara S, Fujisawa H, Kikuchi A, Kaibuchi K. Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin. The Journal of Biological Chemistry. 274: 26044-50. PMID 10473551 DOI: 10.1074/Jbc.274.37.26044  0.301
1999 Kuroda S, Fukata M, Nakagawa M, Kaibuchi K. Cdc42, Rac1, and their effector IQGAP1 as molecular switches for cadherin-mediated cell-cell adhesion. Biochemical and Biophysical Research Communications. 262: 1-6. PMID 10448058 DOI: 10.1006/Bbrc.1999.1122  0.32
1999 Maesaki R, Shimizu T, Ihara K, Kuroda S, Kaibuchi K, Hakoshima T. Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA. Journal of Structural Biology. 126: 166-70. PMID 10388627 DOI: 10.1006/Jsbi.1999.4114  0.349
1999 Hoshino M, Sone M, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C. Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. The Journal of Biological Chemistry. 274: 17837-44. PMID 10364228 DOI: 10.1074/Jbc.274.25.17837  0.367
1999 Fukata Y, Oshiro N, Kinoshita N, Kawano Y, Matsuoka Y, Bennett V, Matsuura Y, Kaibuchi K. Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility. The Journal of Cell Biology. 145: 347-61. PMID 10209029 DOI: 10.1083/Jcb.145.2.347  0.357
1999 Nilius B, Voets T, Prenen J, Barth H, Aktories K, Kaibuchi K, Droogmans G, Eggermont J. Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells. The Journal of Physiology. 516: 67-74. PMID 10066923 DOI: 10.1111/J.1469-7793.1999.067Aa.X  0.355
1999 Feng J, Ito M, Kureishi Y, Ichikawa K, Amano M, Isaka N, Okawa K, Iwamatsu A, Kaibuchi K, Hartshorne DJ, Nakano T. Rho-associated kinase of chicken gizzard smooth muscle. The Journal of Biological Chemistry. 274: 3744-52. PMID 9920927 DOI: 10.1074/Jbc.274.6.3744  0.37
1998 Oshiro N, Fukata Y, Kaibuchi K. Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. The Journal of Biological Chemistry. 273: 34663-6. PMID 9856983 DOI: 10.1074/Jbc.273.52.34663  0.386
1998 Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, Ookubo T, Izawa I, Nagase T, Nomura N, Tani H, Shoji I, Matsuura Y, Yonehara S, Kaibuchi K. Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (New York, N.Y.). 281: 832-5. PMID 9694656 DOI: 10.1126/Science.281.5378.832  0.303
1998 Fukata Y, Kimura K, Oshiro N, Saya H, Matsuura Y, Kaibuchi K. Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. The Journal of Cell Biology. 141: 409-18. PMID 9548719 DOI: 10.1083/Jcb.141.2.409  0.396
1998 Kimura K, Fukata Y, Matsuoka Y, Bennett V, Matsuura Y, Okawa K, Iwamatsu A, Kaibuchi K. Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase. The Journal of Biological Chemistry. 273: 5542-8. PMID 9488679 DOI: 10.1074/Jbc.273.10.5542  0.391
1998 Kobayashi K, Kuroda S, Fukata M, Nakamura T, Nagase T, Nomura N, Matsuura Y, Yoshida-Kubomura N, Iwamatsu A, Kaibuchi K. p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase. The Journal of Biological Chemistry. 273: 291-5. PMID 9417078 DOI: 10.1074/Jbc.273.1.291  0.357
1997 Kuroda S, Fukata M, Fujii K, Nakamura T, Izawa I, Kaibuchi K. Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases. Biochemical and Biophysical Research Communications. 240: 430-5. PMID 9388496 DOI: 10.1006/Bbrc.1997.7675  0.307
1997 Fukata M, Kuroda S, Fujii K, Nakamura T, Shoji I, Matsuura Y, Okawa K, Iwamatsu A, Kikuchi A, Kaibuchi K. Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42. The Journal of Biological Chemistry. 272: 29579-83. PMID 9368021 DOI: 10.1074/Jbc.272.47.29579  0.304
1997 Kobayashi M, Nagata S, Kita Y, Nakatsu N, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Saitoh I, Fukui Y. Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system. The Journal of Biological Chemistry. 272: 16089-92. PMID 9195902 DOI: 10.1074/Jbc.272.26.16089  0.391
1997 Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, Ito M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. The Journal of Biological Chemistry. 272: 12257-60. PMID 9139666 DOI: 10.1074/Jbc.272.19.12257  0.336
1997 Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y, Kaibuchi K. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science (New York, N.Y.). 275: 1308-11. PMID 9036856 DOI: 10.1126/Science.275.5304.1308  0.321
1997 Sone M, Hoshino M, Suzuki E, Kuroda S, Kaibuchi K, Nakagoshi H, Saigo K, Nabeshima Y, Hama C. Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers. Science (New York, N.Y.). 275: 543-7. PMID 8999801 DOI: 10.1126/Science.275.5299.543  0.351
1996 Kuroda S, Fukata M, Kobayashi K, Nakafuku M, Nomura N, Iwamatsu A, Kaibuchi K. Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1 Journal of Biological Chemistry. 271: 23363-23367. PMID 8798539 DOI: 10.1074/Jbc.271.38.23363  0.365
1996 Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). The Journal of Biological Chemistry. 271: 20246-9. PMID 8702756 DOI: 10.1074/Jbc.271.34.20246  0.371
1996 Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho- kinase) Science. 273: 245-248. PMID 8662509 DOI: 10.1126/Science.273.5272.245  0.388
1996 Shibata H, Mukai H, Inagaki Y, Homma Y, Kimura K, Kaibuchi K, Narumiya S, Ono Y. Characterization of the interaction between RhoA and the amino-terminal region of PKN. Febs Letters. 385: 221-4. PMID 8647255 DOI: 10.1016/0014-5793(96)00385-7  0.301
1996 Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. The Embo Journal. 15: 2208-2216. DOI: 10.1002/J.1460-2075.1996.Tb00574.X  0.39
1995 Kuroda S, Shimizu K, Yamamori B, Matsuda S, Imazumi K, Kaibuchi K, Takai Y. Purification and characterization of REKS from Xenopus eggs. Identification of REKS as a Ras-dependent mitogen-activated protein kinase kinase kinase. The Journal of Biological Chemistry. 270: 2460-5. PMID 7852306 DOI: 10.1074/Jbc.270.6.2460  0.315
1995 Takai Y, Kaibuchi K, Kikuchi A, Sasaki T. Effects of prenyl modifications on interactions of small G proteins with regulators. Methods in Enzymology. 250: 122-33. PMID 7651145 DOI: 10.1016/0076-6879(95)50067-7  0.316
1994 Kim YS, Hong KS, Seong YS, Park JB, Kuroda S, Kishi K, Kaibuchi K, Takai Y. Phosphorylation and activation of mitogen-activated protein kinase by kainic acid-induced seizure in rat hippocampus. Biochemical and Biophysical Research Communications. 202: 1163-8. PMID 7519421 DOI: 10.1006/Bbrc.1994.2050  0.346
1993 Takai Y, Kaibuchi K, Kikuchi A, Sasaki T. GDP/GTP Exchange Proteins for Small GTP-Binding Proteins Handbook of Experimental Pharmacology. 108: 613-624. DOI: 10.1007/978-3-642-78267-1_39  0.309
1992 Muramatsu M, Kaibuchi K, Arai K. Protein kinase C mutants in the auto-inhibitory region exhibit two distinct properties. Febs Letters. 311: 75-9. PMID 1397296 DOI: 10.1016/0014-5793(92)81371-R  0.402
1991 Itoh T, Kaibuchi K, Sasaki T, Takai Y. The smg GDS-induced activation of smg p21 is initiated by cyclic AMP-dependent protein kinase-catalyzed phosphorylation of smg p21. Biochemical and Biophysical Research Communications. 177: 1319-24. PMID 1905539 DOI: 10.1016/0006-291X(91)90685-Z  0.388
1991 Sasaki T, Kaibuchi K, Kabcenell AK, Novick PJ, Takai Y. A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein. Molecular and Cellular Biology. 11: 2909-12. PMID 1901952 DOI: 10.1128/Mcb.11.5.2909  0.358
1991 Araki S, Kaibuchi K, Sasaki T, Hata Y, Takai Y. Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein. Molecular and Cellular Biology. 11: 1438-47. PMID 1899908 DOI: 10.1128/Mcb.11.3.1438  0.309
1991 Fujimoto A, Kai S, Akiyama T, Toyoshima K, Kaibuchi K, Takai Y, Yamamoto T. Transactivation of the TPA-responsive element by the oncogenic C-erbB-2 protein is partly mediated by protein kinase C. Biochemical and Biophysical Research Communications. 178: 724-32. PMID 1677566 DOI: 10.1016/0006-291X(91)90168-7  0.356
1988 Matsumoto K, Nakafuku M, Nakayama N, Miyajima I, Kaibuchi K, Miyajima A, Brenner C, Arai K, Kaziro Y. The role of G proteins in yeast signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 567-575. PMID 2855496 DOI: 10.1101/Sqb.1988.053.01.065  0.304
1987 Miyajima I, Nakafuku M, Nakayama N, Brenner C, Miyajima A, Kaibuchi K, Arai Ki, Kaziro Y, Matsumoto K. GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction Cell. 50: 1011-1019. PMID 3113739 DOI: 10.1016/0092-8674(87)90167-X  0.337
1985 Kaibuchi K, Takai Y, Nishizuka Y. Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes. The Journal of Biological Chemistry. 260: 1366-9. PMID 3155734  0.518
1984 Kikkawa U, Kaibuchi K, Castagna M, Yamanishi J, Sano K, Tanaka Y, Miyake R, Takai Y, Nishizuka Y. Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 437-42. PMID 6328930  0.518
1984 Miyake R, Tanaka Y, Tsuda T, Kaibuchi K, Kikkawa U, Nishizuka Y. Activation of protein kinase C by non-phorbol tumor promoter, mezerein. Biochemical and Biophysical Research Communications. 121: 649-56. PMID 6233978 DOI: 10.1016/0006-291X(84)90231-6  0.564
1984 Katakami Y, Kaibuchi K, Sawamura M, Takai Y, Nishizuka Y. Synergistic action of protein kinase C and calcium for histamine release from rat peritoneal mast cells. Biochemical and Biophysical Research Communications. 121: 573-8. PMID 6203533 DOI: 10.1016/0006-291X(84)90220-1  0.582
1984 Takai Y, Kikkawa U, Kaibuchi K, Nishizuka Y. Membrane phospholipid metabolism and signal transduction for protein phosphorylation. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 18: 119-58. PMID 6093478  0.486
1984 Nishizuka Y, Takai Y, Kishimoto A, Kikkawa U, Kaibuchi K. Phospholipid turnover in hormone action. Recent Progress in Hormone Research. 40: 301-45. PMID 6091193 DOI: 10.1016/B978-0-12-571140-1.50012-8  0.529
1983 Kaibuchi K, Takai Y, Sawamura M, Hoshijima M, Fujikura T, Nishizuka Y. Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation. The Journal of Biological Chemistry. 258: 6701-4. PMID 6406488  0.538
1983 Yamanishi J, Takai Y, Kaibuchi K, Sano K, Castagna M, Nishizuka Y. Synergistic functions of phorbol ester and calcium in serotonin release from human platelets. Biochemical and Biophysical Research Communications. 112: 778-86. PMID 6405748 DOI: 10.1016/0006-291X(83)91529-2  0.568
1983 Kajikawa N, Kaibuchi K, Matsubara T, Kikkawa U, Takai Y, Nishizuka Y, Itoh K, Tomioka C. A possible role of protein kinase C in signal-induced lysosomal enzyme release. Biochemical and Biophysical Research Communications. 116: 743-50. PMID 6228230 DOI: 10.1016/0006-291X(83)90587-9  0.552
1982 Ieyasu H, Takai Y, Kaibuchi K, Sawamura M, Nishizuka Y. A role of calcium-activated, phospholipid-dependent protein kinase in platelet-activating factor-induced serotonin release from rabbit platelets. Biochemical and Biophysical Research Communications. 108: 1701-8. PMID 7181916 DOI: 10.1016/S0006-291X(82)80107-1  0.585
1982 Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. The Journal of Biological Chemistry. 257: 7847-51. PMID 7085651  0.537
1982 Takai Y, Minakuchi R, Kikkawa U, Sano K, Kaibuchi K, Yu B, Matsubara T, Nishizuka Y. Membrane phospholipid turnover, receptor function and protein phosphorylation. Progress in Brain Research. 56: 287-301. PMID 6298874 DOI: 10.1016/S0079-6123(08)63780-2  0.511
1982 Kaibuchi K, Takai Y, Ogawa Y, Kimura S, Nishizuka Y, Nakamura T, Tomomura A, Ichihara A. Inhibitory action of adenosine 3',5'-monophosphate on phosphatidylinositol turnover: difference in tissue response. Biochemical and Biophysical Research Communications. 104: 105-12. PMID 6280686 DOI: 10.1016/0006-291X(82)91946-5  0.54
1982 Takai Y, Kaibuchi K, Sano K, Nishizuka Y. Counteraction of calcium-activated, phospholipid-dependent protein kinase activation by adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in platelets. Journal of Biochemistry. 91: 403-6. PMID 6279587 DOI: 10.1093/Oxfordjournals.Jbchem.A133700  0.578
1982 Kaibuchi K, Sano K, Hoshijima M, Takai Y, Nishizuka Y. Phosphatidylinositol turnover in platelet activation; calcium mobilization and protein phosphorylation. Cell Calcium. 3: 323-35. PMID 6218878 DOI: 10.1016/0143-4160(82)90020-3  0.571
1981 Takai Y, Kishimoto A, Kawahara Y, Minakuchi R, Sano K, Kikkawa U, Mori T, Yu B, Kaibuchi K, Nishizuka Y. Calcium and phosphatidylinositol turnover as signalling for transmembrane control of protein phosphorylation. Advances in Cyclic Nucleotide Research. 14: 301-13. PMID 7282484  0.491
1981 Kaibuchi K, Takai Y, Nishizuka Y. Cooperative roles of various membrane phospholipids in the activation of calcium-activated, phospholipid-dependent protein kinase. The Journal of Biological Chemistry. 256: 7146-9. PMID 7251589  0.495
1981 Takai Y, Kaibuchi K, Matsubara T, Nishizuka Y. Inhibitory action of guanosine 3', 5'-monophosphate on thrombin-induced phosphatidylinositol turnover and protein phosphorylation in human platelets. Biochemical and Biophysical Research Communications. 101: 61-7. PMID 6269550 DOI: 10.1016/S0006-291X(81)80010-1  0.558
1981 KAWAHARA Y, SANO K, MINAKUCHI R, KIKKAWA U, YU B, MORI T, KAIBUCHI K, TAKAHASHI J, TAKAI Y, NISHIZUKA Y. Blood & Vessel. 12: 532-540. DOI: 10.2491/Jjsth1970.12.532  0.502
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