| Year |
Citation |
Score |
| 2023 |
Merritt CR, Garcia EJ, Brehm VD, Fox RG, Moeller FG, Anastasio NC, Cunningham KA. Ghrelin receptor antagonist JMV2959 blunts cocaine and oxycodone drug-seeking, but not self-administration, in male rats. Frontiers in Pharmacology. 14: 1268366. PMID 37795028 DOI: 10.3389/fphar.2023.1268366 |
0.368 |
|
| 2023 |
Chen J, Garcia EJ, Merritt CR, Zamora JC, Bolinger AA, Pazdrak K, Stafford SJ, Mifflin RC, Wold EA, Wild CT, Chen H, Anastasio NC, Cunningham KA, Zhou J. Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT Receptor and Dual 5-HT/5-HT Receptor Modulators. Journal of Medicinal Chemistry. PMID 37462530 DOI: 10.1021/acs.jmedchem.3c00908 |
0.35 |
|
| 2022 |
Merritt CR, Smith AE, Khanipov K, Golovko G, Dineley KT, Anastasio NC, Cunningham KA. Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex. Frontiers in Pharmacology. 13: 1022863. PMID 36588704 DOI: 10.3389/fphar.2022.1022863 |
0.394 |
|
| 2022 |
Ma L, Cunningham KA, Anastasio NC, Bjork JM, Taylor BA, Arias AJ, Riley BP, Snyder AD, Moeller FG. A serotonergic biobehavioral signature differentiates cocaine use disorder participants administered mirtazapine. Translational Psychiatry. 12: 187. PMID 35523779 DOI: 10.1038/s41398-022-01934-w |
0.346 |
|
| 2021 |
Kasper JM, Smith AE, Miller SN, Ara, Russell WK, Cunningham KA, Hommel JD. Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34916591 DOI: 10.1038/s41386-021-01234-9 |
0.35 |
|
| 2021 |
Johns SE, Keyser-Marcus L, Abbate A, Boone E, Van Tassell B, Cunningham KA, Anastasio NC, Poklis JL, Ramey T, Moeller FG. Safety and Preliminary Efficacy of Lorcaserin for Cocaine Use Disorder: A Phase I Randomized Clinical Trial. Frontiers in Psychiatry. 12: 666945. PMID 34276440 DOI: 10.3389/fpsyt.2021.666945 |
0.371 |
|
| 2020 |
De Deurwaerdère P, Chagraoui A, Cunningham KA. Editorial: Contemporary Perspective on 5-HT Receptor Function and Its Pharmacological Targeting. Frontiers in Pharmacology. 11: 606414. PMID 33324228 DOI: 10.3389/fphar.2020.606414 |
0.324 |
|
| 2020 |
Land MA, Ramesh D, Miller AL, Pyles RB, Cunningham KA, Moeller FG, Anastasio NC. Methylation Patterns of the Associate With Relapse-Related Behaviors in Cocaine-Dependent Participants. Frontiers in Psychiatry. 11: 532. PMID 32587535 DOI: 10.3389/Fpsyt.2020.00532 |
0.444 |
|
| 2020 |
Wold EA, Garcia EJ, Wild C, Miszkiel JM, Soto CA, Chen J, Pazdrak K, Fox RG, Anastasio NC, Cunningham KA, Zhou J. Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor Positive Allosteric Modulators with Enhanced Drug-Like Properties. Journal of Medicinal Chemistry. PMID 32567857 DOI: 10.1021/Acs.Jmedchem.9B01953 |
0.416 |
|
| 2020 |
Anastasio NC, Sholler DJ, Fox RG, Stutz SJ, Merritt CR, Bjork JM, Moeller FG, Cunningham KA. Suppression of cocaine relapse-like behaviors upon pimavanserin and lorcaserin co-administration. Neuropharmacology. 168: 108009. PMID 32145488 DOI: 10.1016/J.Neuropharm.2020.108009 |
0.543 |
|
| 2020 |
Nigam K, Ma L, Cunningham K, Moeller F, Bjork J. Brain Signatures of Diminished Proactive Inhibitory Control in Cocaine Use Disorder Biological Psychiatry. 87: S257-S258. DOI: 10.1016/J.Biopsych.2020.02.666 |
0.389 |
|
| 2019 |
Land MA, Chapman HL, Davis-Reyes BD, Felsing DE, Allen JA, Moeller FG, Elferink LA, Cunningham KA, Anastasio NC. Serotonin 5-HT Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro. Scientific Reports. 9: 16737. PMID 31723224 DOI: 10.1038/S41598-019-53124-2 |
0.4 |
|
| 2019 |
Soto CA, Du HC, Fox RG, Yang T, Hooson J, Anastasio NC, Gilbertson SR, Cunningham KA. and Analyses of Novel Peptidomimetic Disruptors for the Serotonin 5-HT Receptor Interaction With Phosphatase and Tensin Homolog. Frontiers in Pharmacology. 10: 907. PMID 31507411 DOI: 10.3389/Fphar.2019.00907 |
0.433 |
|
| 2019 |
McGrath EL, Schlagal CR, Cortez I, Dunn TJ, Gao J, Fox RG, Stutz SJ, Kuo YF, Hommel JD, Dineley KT, Cunningham KA, Kaphalia BS, Wu P. Chronic poly-drug administration damages adult mouse brain neural stem cells. Brain Research. 146425. PMID 31473223 DOI: 10.1016/J.Brainres.2019.146425 |
0.353 |
|
| 2019 |
Wold EA, Wild CT, Cunningham KA, Zhou J. Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development. Current Topics in Medicinal Chemistry. PMID 31288724 DOI: 10.2174/1568026619666190709101449 |
0.374 |
|
| 2019 |
Fongang B, Cunningham KA, Rowicka M, Kudlicki A. Coevolution of Residues Provides Evidence of a Functional Heterodimer of 5-HTR and 5-HTR Involving both Intracellular and Extracellular Domains. Neuroscience. PMID 31158438 DOI: 10.1016/J.Neuroscience.2019.05.013 |
0.318 |
|
| 2019 |
Price AE, Sholler DJ, Stutz SJ, Anastasio NC, Cunningham KA. Endogenous Serotonin 5-HT and 5-HT Receptors Associate in the Medial Prefrontal Cortex. Acs Chemical Neuroscience. PMID 30645940 DOI: 10.1021/Acschemneuro.8B00669 |
0.416 |
|
| 2018 |
Price AE, Brehm VD, Hommel JD, Anastasio NC, Cunningham KA. Pimavanserin and Lorcaserin Attenuate Measures of Binge Eating in Male Sprague-Dawley Rats. Frontiers in Pharmacology. 9: 1424. PMID 30581386 DOI: 10.3389/Fphar.2018.01424 |
0.41 |
|
| 2018 |
Sholler DJ, Stutz SJ, Fox RG, Boone EL, Wang Q, Rice KC, Moeller FG, Anastasio NC, Cunningham KA. The 5-HT Receptor (5-HTR) Regulates Impulsive Action and Cocaine Cue Reactivity in Male Sprague-Dawley Rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 30373886 DOI: 10.1124/Jpet.118.251199 |
0.526 |
|
| 2018 |
Zhou J, Cunningham KA. Positive-allosteric modulation of the 5-HT receptor: implications for neuropsychopharmacology and neurotherapeutics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30202047 DOI: 10.1038/S41386-018-0190-X |
0.451 |
|
| 2018 |
Felsing DE, Anastasio NC, Miszkiel JM, Gilbertson SR, Allen JA, Cunningham KA. Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction. Plos One. 13: e0203137. PMID 30157263 DOI: 10.1371/Journal.Pone.0203137 |
0.389 |
|
| 2018 |
Price AE, Anastasio NC, Stutz SJ, Hommel JD, Cunningham KA. Serotonin 5-HT Receptor Activation Suppresses Binge Intake and the Reinforcing and Motivational Properties of High-Fat Food. Frontiers in Pharmacology. 9: 821. PMID 30100875 DOI: 10.3389/Fphar.2018.00821 |
0.406 |
|
| 2018 |
Dimet AL, Cisneros IE, Fox RG, Stutz SJ, Anastasio NC, Cunningham KA, Dineley KT. A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder. Journal of Visualized Experiments : Jove. PMID 29985329 DOI: 10.3791/55864 |
0.426 |
|
| 2018 |
Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J. Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-Carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor. Journal of Medicinal Chemistry. PMID 29620897 DOI: 10.1021/Acs.Jmedchem.8B00401 |
0.488 |
|
| 2018 |
Cisneros IE, Erdenizmenli M, Cunningham KA, Paessler S, Dineley KT. Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes. Neuropharmacology. PMID 29578037 DOI: 10.1016/J.Neuropharm.2018.03.019 |
0.405 |
|
| 2018 |
Gilbertson SR, Chen YC, Soto CA, Yang Y, Rice KC, Cunningham KA, Anastasio NC. Synthesis and activity of functionalizable derivatives of the serotonin (5-HT) 5-HTreceptor (5-HTR) antagonist M100907. Bioorganic & Medicinal Chemistry Letters. PMID 29555153 DOI: 10.1016/J.Bmcl.2018.02.058 |
0.399 |
|
| 2017 |
Soto CA, Shashack MJ, Fox RG, Bubar MJ, Rice KC, Watson CS, Cunningham KA, Gilbertson SR, Anastasio NC. Novel Bivalent 5-HT2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo. Acs Chemical Neuroscience. PMID 29111677 DOI: 10.1021/Acschemneuro.7B00309 |
0.773 |
|
| 2017 |
Ma L, Steinberg JL, Cunningham KA, Bjork JM, Lane SD, Schmitz JM, Burroughs T, Narayana PA, Kosten TR, Bechara A, Moeller FG. Altered anterior cingulate cortex to hippocampus effective connectivity in response to drug cues in men with cocaine use disorder. Psychiatry Research. PMID 29108734 DOI: 10.1016/J.Pscychresns.2017.10.012 |
0.407 |
|
| 2017 |
Simmler LD, Anacker AMJ, Levin MH, Vaswani NM, Gresch PJ, Nackenoff AG, Anastasio NC, Stutz SJ, Cunningham KA, Wang J, Zhang B, Keith Henry L, Stewart A, Veenstra-VanderWeele J, Blakely RD. Serotonin Transporter Blockade Contributes to the Behavioral, Neuronal, and Molecular Effects of Cocaine. British Journal of Pharmacology. PMID 28585320 DOI: 10.1111/Bph.13899 |
0.534 |
|
| 2017 |
Schmitz JM, Green CE, Hasan KM, Vincent J, Suchting R, Weaver MF, Moeller FG, Narayana PA, Cunningham KA, Dineley KT, Lane SD. PPAR-gamma agonist pioglitazone modifies craving intensity and brain white matter integrity in patients with primary cocaine use disorder: A double-blind randomized controlled pilot trial. Addiction (Abingdon, England). PMID 28498501 DOI: 10.1111/Add.13868 |
0.41 |
|
| 2017 |
Chen YC, Hartley RM, Anastasio NC, Cunningham KA, Gilbertson SR. Synthesis and structure-activity relationships of tools based on WAY163909, a 5-HT2c receptor agonist. Acs Chemical Neuroscience. PMID 28414422 DOI: 10.1021/Acschemneuro.6B00439 |
0.304 |
|
| 2017 |
Neelakantan H, Holliday ED, Fox RG, Stutz SJ, Comer SD, Haney M, Anastasio NC, Moeller FG, Cunningham KA. Lorcaserin suppresses oxycodone self-administration and relapse vulnerability in rats. Acs Chemical Neuroscience. PMID 28107783 DOI: 10.1021/Acschemneuro.6B00413 |
0.416 |
|
| 2017 |
Gao Y, Yao T, Deng Z, Sohn JW, Sun J, Huang Y, Kong X, Yu KJ, Wang RT, Chen H, Guo H, Yan J, Cunningham KA, Chang Y, Liu T, et al. TrpC5 Mediates Acute Leptin and Serotonin Effects via Pomc Neurons. Cell Reports. 18: 583-592. PMID 28099839 DOI: 10.1016/J.Celrep.2016.12.072 |
0.354 |
|
| 2017 |
Soto C, Fox RG, Anastasio NC, Du HC, Gilbertson S, Cunningham KA. Disruption of the serotonin 5-HT2C receptor interaction with protein phosphatase and tensin homologue regulates the behavioral effects of the selective 5-HT2CR agonist WAY163909 Drug and Alcohol Dependence. 171: e194. DOI: 10.1016/J.Drugalcdep.2016.08.530 |
0.383 |
|
| 2017 |
Moeller FG, Ma L, Steinberg J, Bjork J, Lane SD, Narayana P, Kosten T, Bechara A, Schmitz J, Price AE, Cunningham KA. Effective connectivity of attentional bias in cocaine dependence Drug and Alcohol Dependence. 171: e147. DOI: 10.1016/J.Drugalcdep.2016.08.405 |
0.42 |
|
| 2017 |
McGrath E, Wu P, Cunningham KA, Dunn T, Gao J, Grant AC, Dineley K, Allende-labastida J, Kaphalia B. Regional- and sex-dependent effects of chronic ethanol and cocaine co-administration on adult neural stem cell survival and differentiation Drug and Alcohol Dependence. 171: e138. DOI: 10.1016/J.Drugalcdep.2016.08.383 |
0.345 |
|
| 2017 |
Lane SD, Hasan KM, Mwangi B, Narayana P, Vincent J, Gerard Moeller F, Steinberg J, Dineley K, Cunningham KA, Schmitz J. Changes in brain white matter integrity after Ppar-gamma agonist treatment for cocaine use disorder Drug and Alcohol Dependence. 171: e113-e114. DOI: 10.1016/J.Drugalcdep.2016.08.316 |
0.379 |
|
| 2017 |
Dimet A, Denner L, Miller R, Cunningham KA, Huentelman M, Lane SD, Dineley K. PPARγ agonism to treat white matter damage in cocaine use disorder Drug and Alcohol Dependence. 171: e54-e55. DOI: 10.1016/J.Drugalcdep.2016.08.161 |
0.381 |
|
| 2016 |
Miller WR, Fox RG, Stutz SJ, Lane SD, Denner L, Cunningham KA, Dineley KT. PPARγ agonism attenuates cocaine cue reactivity. Addiction Biology. PMID 27862692 DOI: 10.1111/Adb.12471 |
0.459 |
|
| 2016 |
Kasper JM, McCue DL, Milton AJ, Szwed A, Sampson CM, Huang M, Carlton S, Meltzer HY, Cunningham KA, Hommel JD. Gamma-Aminobutyric Acidergic Projections From the Dorsal Raphe to the Nucleus Accumbens Are Regulated by Neuromedin U. Biological Psychiatry. PMID 27105831 DOI: 10.1016/J.Biopsych.2016.02.031 |
0.407 |
|
| 2016 |
Swinford-Jackson SE, Anastasio NC, Fox RG, Stutz SJ, Cunningham KA. Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system. Neuroscience. 324: 50-61. PMID 26926963 DOI: 10.1016/J.Neuroscience.2016.02.052 |
0.569 |
|
| 2016 |
Rudra JS, Ding Y, Neelakantan H, Ding C, Appavu R, Stutz SJ, Snook JD, Chen H, Cunningham KA, Zhou J. Suppression of Cocaine-evoked Hyperactivity by Self-adjuvanting and Multivalent Peptide Nanofiber Vaccines. Acs Chemical Neuroscience. PMID 26926328 DOI: 10.1021/Acschemneuro.5B00345 |
0.401 |
|
| 2016 |
Swinford-Jackson SE, Anastasio NC, Fox RG, Stutz SJ, Cunningham KA. Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system Neuroscience. 324: 50-61. DOI: 10.1016/j.neuroscience.2016.02.052 |
0.472 |
|
| 2015 |
Anastasio NC, Stutz SJ, Fink LH, Swinford-Jackson SE, Sears RM, DiLeone RJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. Acs Chemical Neuroscience. PMID 26120876 DOI: 10.1021/Acschemneuro.5B00094 |
0.678 |
|
| 2015 |
Liu S, Maili L, Lane SD, Schmitz JM, Spellicy CJ, Cunningham KA, Moeller FG, Nielsen DA. Serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity. Psychiatric Genetics. PMID 26110342 DOI: 10.1097/Ypg.0000000000000094 |
0.406 |
|
| 2015 |
Ma L, Steinberg JL, Cunningham KA, Lane SD, Bjork JM, Neelakantan H, Price AE, Narayana PA, Kosten TR, Bechara A, Moeller FG. Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls. Neuroimage. Clinical. 7: 837-47. PMID 26082893 DOI: 10.1016/J.Nicl.2015.03.015 |
0.359 |
|
| 2015 |
Hamilton KR, Littlefield AK, Anastasio NC, Cunningham KA, Fink LH, Wing VC, Mathias CW, Lane SD, Schütz CG, Swann AC, Lejuez CW, Clark L, Moeller FG, Potenza MN. Rapid-response impulsivity: definitions, measurement issues, and clinical implications. Personality Disorders. 6: 168-81. PMID 25867840 DOI: 10.1037/Per0000100 |
0.629 |
|
| 2015 |
Fink LH, Anastasio NC, Fox RG, Rice KC, Moeller FG, Cunningham KA. Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1957-68. PMID 25666313 DOI: 10.1038/Npp.2015.46 |
0.706 |
|
| 2015 |
De La Garza R, Bubar MJ, Carbone CL, Moeller FG, Newton TF, Anastasio NC, Harper TA, Ware DL, Fuller MA, Holstein GJ, Jayroe JB, Bandak SI, Reiman KZ, Neale AC, Pickford LB, ... Cunningham KA, et al. Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 59: 40-8. PMID 25602710 DOI: 10.1016/J.Pnpbp.2015.01.009 |
0.783 |
|
| 2015 |
Martin CB, Martin VS, Trigo JM, Chevarin C, Maldonado R, Fink LH, Cunningham KA, Hamon M, Lanfumey L, Mongeau R. 5-HT2C receptor desensitization moderates anxiety in 5-HTT deficient mice: from behavioral to cellular evidence. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522398 DOI: 10.1093/Ijnp/Pyu056 |
0.675 |
|
| 2015 |
Howell LL, Cunningham KA. Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. Pharmacological Reviews. 67: 176-97. PMID 25505168 DOI: 10.1124/Pr.114.009514 |
0.564 |
|
| 2015 |
Tannu NS, Schmitz J, Lane SD, Green C, Cunningham KA, Suchting R, Herrera J, Narayana P. Proteomics analyses: Peroxisome proliferator-activated receptor gamma agonist for chronic cocaine administration in rodents Drug and Alcohol Dependence. 156: e219. DOI: 10.1016/J.Drugalcdep.2015.07.590 |
0.457 |
|
| 2015 |
Swinford-Jackson SE, Anastasio NC, Stutz SJ, Fox RG, Cunningham KA. Differential modulation of cocaine-related behaviors consequent to knockdown of serotonin 5-HT 2C receptor in the nucleus accumbens shell vs. ventral tegmental area Drug and Alcohol Dependence. 156: e218. DOI: 10.1016/J.Drugalcdep.2015.07.587 |
0.558 |
|
| 2015 |
Stutz SJ, Anastasio NC, Cunningham KA. The role of serotonin 2A (5-HT 2A ) and 2C (5-HT 2C ) receptors in the association between BINGE eating and impulsive action Drug and Alcohol Dependence. 156: e215. DOI: 10.1016/J.Drugalcdep.2015.07.580 |
0.455 |
|
| 2015 |
Soto C, Anastasio NC, Swinford-Jackson SE, Fox RG, Du HC, Gilbertson S, Cunningham KA. Disruption of serotonin 5-HT 2c receptor (5-HT 2c R) interaction with protein phosphatase and tensin homologue (PTEN) results in distinct patterns of cortical phosphorylated extracellular-signal regulated kinase 1/2 (pERK 1/2 ) Drug and Alcohol Dependence. 156: e208. DOI: 10.1016/J.Drugalcdep.2015.07.561 |
0.449 |
|
| 2015 |
Neelakantan H, Stutz SJ, Bubar MJ, Sears RM, DiLeone RJ, Cunningham KA. Serotonin 5-HT 2C receptors in the ventral subiculum regulate cocaine-evoked hyperactivity in rats Drug and Alcohol Dependence. 156: e161-e162. DOI: 10.1016/J.Drugalcdep.2015.07.440 |
0.809 |
|
| 2015 |
McGrath E, Wu P, Gao J, Dunn T, Allende-labastida J, Cunningham KA, Dineley K, Kaphalia B, Wang L, Hao Y. The effect of chronic concurrent intake of alcohol and cocaine on neural stem cell survival and differentiation Drug and Alcohol Dependence. 156: e146. DOI: 10.1016/J.Drugalcdep.2015.07.399 |
0.328 |
|
| 2015 |
Ma L, Steinberg JL, Cunningham KA, Lane SD, Bjork JM, Narayana P, Kosten T, Bechara A, Moeller FG. Inhibitory control: A brain connectivity study comparing cocaine-dependent subjects and controls Drug and Alcohol Dependence. 156: e137-e138. DOI: 10.1016/J.Drugalcdep.2015.07.376 |
0.367 |
|
| 2015 |
Hartley RM, Gilbertson S, Chen Y, Anastasio NC, Fox RG, Stutz SJ, Watson C, Cunningham KA. Novel bivalent serotonin 5-HT 2A and 5-HT 2C receptor ligands demonstrate distinct activities in vitro and in vivo Drug and Alcohol Dependence. 156: e91. DOI: 10.1016/J.Drugalcdep.2015.07.1164 |
0.471 |
|
| 2015 |
Fox RG, Stutz SJ, Comer S, Haney M, Anastasio NC, Moeller F, Cunningham KA. Serotonin (5-HT) 5-HT 2C receptor (5-HT 2C R) agonist lorcaserin suppresses cocaine or oxycodone cue reactivity Drug and Alcohol Dependence. 156: e73. DOI: 10.1016/J.Drugalcdep.2015.07.1117 |
0.314 |
|
| 2015 |
Wild C, Ding C, Zhang G, Anastasio N, Moncrief JS, Carbonaro T, Fox R, Stutz S, Hartley R, Smith T, Cunningham K, Zhou J. Targeting the serotonin (5-HT) 5-HT2c receptor: Rational design of small molecule allosteric modulators to treat psychostimulant use disorders Drug and Alcohol Dependence. 146: e23. DOI: 10.1016/J.Drugalcdep.2014.09.742 |
0.426 |
|
| 2015 |
Swinford-Jackson SE, Anastasio NC, Fox RG, Stutz SJ, Cunningham K. Loss of serotonin (5-HT) 2C receptor (5-HT2CR) tone in the ventral tegmental area modulates cocaine-related behaviors Drug and Alcohol Dependence. 146: e113. DOI: 10.1016/J.Drugalcdep.2014.09.674 |
0.506 |
|
| 2015 |
Soto C, Anastasio NC, Hartley R, Fox RG, Du HC, Gilbertson S, Cunningham K. Serotonin (5-HT)2C receptor interaction with protein phosphatase and tensin homologue results in distinct patterns of cortical ERK1/2 activation Drug and Alcohol Dependence. 146: e104. DOI: 10.1016/J.Drugalcdep.2014.09.651 |
0.451 |
|
| 2015 |
Hartley R, Zhang G, Moncrief JS, Ding C, Anastasio NC, Fox RG, Stutz SJ, Wild C, Zhou J, Cunningham K. Positive allosteric modulators of the serotonin 2C receptor as novel therapeutics for cocaine use disorder Drug and Alcohol Dependence. 146: e137. DOI: 10.1016/J.Drugalcdep.2014.09.290 |
0.462 |
|
| 2015 |
Anastasio NC, Saavedra JL, Miller AL, Pyles RB, Moeller FG, Cunningham K. Epigenetic regulation of cortical serotonin (5-HT) 5-HT2A:5-HT2C receptor balance in maladaptive impulsivity Drug and Alcohol Dependence. 146: e208-e209. DOI: 10.1016/J.Drugalcdep.2014.09.035 |
0.46 |
|
| 2014 |
Anastasio NC, Liu S, Maili L, Swinford SE, Lane SD, Fox RG, Hamon SC, Nielsen DA, Cunningham KA, Moeller FG. Variation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivity. Translational Psychiatry. 4: e369. PMID 24618688 DOI: 10.1038/Tp.2013.131 |
0.566 |
|
| 2014 |
Anastasio NC, Stutz SJ, Fox RG, Sears RM, Emeson RB, DiLeone RJ, O'Neil RT, Fink LH, Li D, Green TA, Moeller FG, Cunningham KA. Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 370-82. PMID 23939424 DOI: 10.1038/Npp.2013.199 |
0.755 |
|
| 2014 |
Cunningham KA, Anastasio NC. Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction. Neuropharmacology. 76: 460-78. PMID 23850573 DOI: 10.1016/J.Neuropharm.2013.06.030 |
0.527 |
|
| 2014 |
Swinford SE, Anastasio NC, Fox R, Stutz S, Cunningham K. Lower Serotonin 2C receptor (5-HT2CR) expression in the ventral tegmental area (VTA) associates with elevated cue reactivity following extended forced abstinence from cocaine-taking Drug and Alcohol Dependence. 140: e221. DOI: 10.1016/J.Drugalcdep.2014.02.614 |
0.483 |
|
| 2014 |
Liu S, Nielsen DA, Lane SD, Schmitz J, Baladandayuthapani V, Cunningham K, Moeller F. Cocaine dependence moderates the relationship between serotonin transporter polymorphisms and measures of impulsivity Drug and Alcohol Dependence. 140: e126. DOI: 10.1016/J.Drugalcdep.2014.02.359 |
0.435 |
|
| 2014 |
Fink LH, Anastasio NC, Fox R, Moeller F, Cunningham K. A predisposition toward inherent impulsivity is associated with elevated 5-HT2AR expression Drug and Alcohol Dependence. 140: e59. DOI: 10.1016/J.Drugalcdep.2014.02.181 |
0.623 |
|
| 2014 |
Anastasio NC, Stutz S, Fink L, Fox R, Sears R, Green T, DiLeone R, Moeller F, Cunningham K. Maladaptive cortical serotonin (5-ht) 5-ht2a:5-ht2c receptor balance generates aberrant impulsivity and elevated cocaine cue reactivity Drug and Alcohol Dependence. 140: e4-e5. DOI: 10.1016/J.Drugalcdep.2014.02.034 |
0.784 |
|
| 2013 |
Liu S, Lane SD, Schmitz JM, Cunningham KA, John VP, Moeller FG. Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects. Journal of Psychopharmacology (Oxford, England). 27: 801-7. PMID 23761390 DOI: 10.1177/0269881113492898 |
0.465 |
|
| 2013 |
Graves SM, Viskniskki AA, Cunningham KA, Napier TC. Serotonin(2C) receptors in the ventral pallidum regulate motor function in rats. Neuroreport. 24: 605-8. PMID 23719021 DOI: 10.1097/Wnr.0B013E3283630Af5 |
0.469 |
|
| 2013 |
Herin DV, Bubar MJ, Seitz PK, Thomas ML, Hillman GR, Tarasenko YI, Wu P, Cunningham KA. Elevated Expression of Serotonin 5-HT(2A) Receptors in the Rat Ventral Tegmental Area Enhances Vulnerability to the Behavioral Effects of Cocaine. Frontiers in Psychiatry. 4: 2. PMID 23390419 DOI: 10.3389/Fpsyt.2013.00002 |
0.84 |
|
| 2013 |
Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW, Laezza FM, Watson CS, ... ... Cunningham KA, et al. Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1615-30. PMID 23345234 DOI: 10.1523/Jneurosci.2656-12.2013 |
0.786 |
|
| 2013 |
Cunningham KA, Anastasio NC, Fox RG, Stutz SJ, Bubar MJ, Swinford SE, Watson CS, Gilbertson SR, Rice KC, Rosenzweig-Lipson S, Moeller FG. Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. Acs Chemical Neuroscience. 4: 110-21. PMID 23336050 DOI: 10.1021/Cn300072U |
0.83 |
|
| 2012 |
Valencia F, Bubar MJ, Milligan G, Cunningham KA, Bourne N. Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model. Sexually Transmitted Diseases. 39: 720-5. PMID 22902670 DOI: 10.1097/Olq.0B013E31825Af129 |
0.709 |
|
| 2012 |
Ding C, Bremer NM, Smith TD, Seitz PK, Anastasio NC, Cunningham KA, Zhou J. Exploration of synthetic approaches and pharmacological evaluation of PNU-69176E and its stereoisomer as 5-HT2C receptor allosteric modulators. Acs Chemical Neuroscience. 3: 538-45. PMID 22860223 DOI: 10.1021/Cn300020X |
0.477 |
|
| 2012 |
Nielsen DA, Huang W, Hamon SC, Maili L, Witkin BM, Fox RG, Cunningham KA, Moeller FG. Forced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary Study. Frontiers in Psychiatry. 3: 60. PMID 22712019 DOI: 10.3389/Fpsyt.2012.00060 |
0.399 |
|
| 2012 |
Seitz PK, Bremer NM, McGinnis AG, Cunningham KA, Watson CS. Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors. Bmc Neuroscience. 13: 25. PMID 22397586 DOI: 10.1186/1471-2202-13-25 |
0.369 |
|
| 2012 |
Liu S, Lane SD, Schmitz JM, Green CE, Cunningham KA, Moeller FG. Increased intra-individual reaction time variability in cocaine-dependent subjects: role of cocaine-related cues. Addictive Behaviors. 37: 193-7. PMID 22047976 DOI: 10.1016/J.Addbeh.2011.10.003 |
0.433 |
|
| 2011 |
Shashack MJ, Cunningham KA, Seitz PK, McGinnis A, Smith T, Watson CS, Gilbertson SR. Synthesis and evaluation of dimeric derivatives of 5-HT(2A) receptor (5-HT(2A)R) antagonist M-100907. Acs Chemical Neuroscience. 2: 640-644. PMID 22247793 DOI: 10.1021/Cn200077Q |
0.43 |
|
| 2011 |
Bubar MJ, Stutz SJ, Cunningham KA. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. Plos One. 6: e20508. PMID 21687728 DOI: 10.1371/Journal.Pone.0020508 |
0.788 |
|
| 2011 |
Cunningham KA, Fox RG, Anastasio NC, Bubar MJ, Stutz SJ, Moeller FG, Gilbertson SR, Rosenzweig-Lipson S. Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues. Neuropharmacology. 61: 513-23. PMID 21575646 DOI: 10.1016/J.Neuropharm.2011.04.034 |
0.831 |
|
| 2011 |
Anastasio NC, Stoffel EC, Fox RG, Bubar MJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-hydroxytryptamine) 5-HT(2A) receptor: association with inherent and cocaine-evoked behavioral disinhibition in rats. Behavioural Pharmacology. 22: 248-61. PMID 21499079 DOI: 10.1097/Fbp.0B013E328345F90D |
0.82 |
|
| 2011 |
Liu S, Lane SD, Schmitz JM, Waters AJ, Cunningham KA, Moeller FG. Relationship between attentional bias to cocaine-related stimuli and impulsivity in cocaine-dependent subjects. The American Journal of Drug and Alcohol Abuse. 37: 117-22. PMID 21204739 DOI: 10.3109/00952990.2010.543204 |
0.42 |
|
| 2010 |
Lanfranco MF, Anastasio NC, Seitz PK, Cunningham KA. Quantification of RNA editing of the serotonin 2C receptor (5-HT(â‚‚C)R) ex vivo. Methods in Enzymology. 485: 311-28. PMID 21050925 DOI: 10.1016/B978-0-12-381296-4.00018-X |
0.437 |
|
| 2010 |
Cunningham KA, Bubar MJ, Anastasio NC. The serotonin 5-HT2C receptor in medial prefrontal cortex exerts rheostatic control over the motivational salience of cocaine-associated cues: new observations from preclinical animal research. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2319-21. PMID 20948510 DOI: 10.1038/Npp.2010.119 |
0.802 |
|
| 2010 |
Anastasio NC, Lanfranco MF, Bubar MJ, Seitz PK, Stutz SJ, McGinnis AG, Watson CS, Cunningham KA. Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. Journal of Neurochemistry. 113: 1504-15. PMID 20345755 DOI: 10.1111/J.1471-4159.2010.06694.X |
0.78 |
|
| 2009 |
dela Cruz AM, Herin DV, Grady JJ, Cunningham KA. Novel approach to data analysis in cocaine-conditioned place preference. Behavioural Pharmacology. 20: 720-30. PMID 19901823 DOI: 10.1097/Fbp.0B013E328333B266 |
0.801 |
|
| 2009 |
Pennock JW, Stegall R, Bubar MJ, Milligan G, Cunningham KA, Bourne N. 3,4-Methylenedioxymethamphetamine increases susceptibility to genital herpes simplex virus infection in mice. The Journal of Infectious Diseases. 200: 1247-50. PMID 19758099 DOI: 10.1086/605891 |
0.711 |
|
| 2009 |
Lanfranco MF, Seitz PK, Morabito MV, Emeson RB, Sanders-Bush E, Cunningham KA. An innovative real-time PCR method to measure changes in RNA editing of the serotonin 2C receptor (5-HT(2C)R) in brain. Journal of Neuroscience Methods. 179: 247-57. PMID 19428534 DOI: 10.1016/J.Jneumeth.2009.01.027 |
0.448 |
|
| 2009 |
Nic Dhonnchadha BA, Fox RG, Stutz SJ, Rice KC, Cunningham KA. Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behavioral Neuroscience. 123: 382-96. PMID 19331461 DOI: 10.1037/A0014592 |
0.562 |
|
| 2009 |
Leggio GM, Cathala A, Moison D, Cunningham KA, Piazza PV, Spampinato U. Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology. 56: 507-13. PMID 18977370 DOI: 10.1016/J.Neuropharm.2008.10.005 |
0.582 |
|
| 2008 |
Bubar MJ, Cunningham KA. Prospects for serotonin 5-HT2R pharmacotherapy in psychostimulant abuse. Progress in Brain Research. 172: 319-46. PMID 18772040 DOI: 10.1016/S0079-6123(08)00916-3 |
0.819 |
|
| 2008 |
Sell SL, Craft RM, Seitz PK, Stutz SJ, Cunningham KA, Thomas ML. Estradiol-sertraline synergy in ovariectomized rats. Psychoneuroendocrinology. 33: 1051-60. PMID 18650020 DOI: 10.1016/J.Psyneuen.2008.05.006 |
0.767 |
|
| 2008 |
Nic Dhonnchadha BA, Cunningham KA. Serotonergic mechanisms in addiction-related memories. Behavioural Brain Research. 195: 39-53. PMID 18639587 DOI: 10.1016/J.Bbr.2008.06.026 |
0.529 |
|
| 2008 |
Berg KA, Clarke WP, Cunningham KA, Spampinato U. Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications. Neuropharmacology. 55: 969-76. PMID 18602407 DOI: 10.1016/J.Neuropharm.2008.06.014 |
0.471 |
|
| 2008 |
Stoffel EC, Cunningham KA. The relationship between the locomotor response to a novel environment and behavioral disinhibition in rats. Drug and Alcohol Dependence. 92: 69-78. PMID 17997051 DOI: 10.1016/J.Drugalcdep.2007.06.012 |
0.434 |
|
| 2008 |
Navailles S, Moison D, Cunningham KA, Spampinato U. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 237-46. PMID 17429406 DOI: 10.1038/Sj.Npp.1301414 |
0.587 |
|
| 2007 |
Shank EJ, Seitz PK, Bubar MJ, Stutz SJ, Cunningham KA. Selective ablation of GABA neurons in the ventral tegmental area increases spontaneous locomotor activity. Behavioral Neuroscience. 121: 1224-33. PMID 18085876 DOI: 10.1037/0735-7044.121.6.1224 |
0.752 |
|
| 2007 |
Liu S, Bubar MJ, Lanfranco MF, Hillman GR, Cunningham KA. Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addiction. Neuroscience. 146: 1677-88. PMID 17467185 DOI: 10.1016/J.Neuroscience.2007.02.064 |
0.791 |
|
| 2007 |
Bubar MJ, Cunningham KA. Distribution of serotonin 5-HT2C receptors in the ventral tegmental area. Neuroscience. 146: 286-97. PMID 17367945 DOI: 10.1016/J.Neuroscience.2006.12.071 |
0.728 |
|
| 2006 |
Watson CS, Alyea RA, Hawkins BE, Thomas ML, Cunningham KA, Jakubas AA. Estradiol effects on the dopamine transporter - protein levels, subcellular location, and function. Journal of Molecular Signaling. 1: 5. PMID 17224081 DOI: 10.1186/1750-2187-1-5 |
0.301 |
|
| 2006 |
Bubar MJ, Cunningham KA. Serotonin 5-HT2A and 5-HT2C receptors as potential targets for modulation of psychostimulant use and dependence. Current Topics in Medicinal Chemistry. 6: 1971-85. PMID 17017968 DOI: 10.2174/156802606778522131 |
0.82 |
|
| 2006 |
Koldzic-Zivanovic N, Seitz PK, Cunningham KA, Thomas ML, Hughes TK. Serotonin regulation of serotonin uptake in RN46A cells. Cellular and Molecular Neurobiology. 26: 979-87. PMID 16858637 DOI: 10.1007/S10571-006-9097-X |
0.451 |
|
| 2006 |
Geng T, Seitz PK, Thomas ML, Xu B, Soman KV, Kurosky A, Luxon BA, Cunningham KA. Use of surface enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS) to study protein expression in a rat model of cocaine withdrawal. Journal of Neuroscience Methods. 158: 1-12. PMID 16766040 DOI: 10.1016/J.Jneumeth.2006.04.025 |
0.371 |
|
| 2006 |
Filip M, Bubar MJ, Cunningham KA. Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats. Psychopharmacology. 183: 482-9. PMID 16261316 DOI: 10.1007/S00213-005-0197-Y |
0.826 |
|
| 2006 |
Liu S, Cunningham KA. Serotonin2C receptors (5-HT2C R) control expression of cocaine-induced conditioned hyperactivity. Drug and Alcohol Dependence. 81: 275-82. PMID 16146672 DOI: 10.1016/J.Drugalcdep.2005.07.007 |
0.505 |
|
| 2006 |
Ross JD, Herin DV, Frankel PS, Thomas ML, Cunningham KA. Chronic treatment with a serotonin(2) receptor (5-HT(2)R) agonist modulates the behavioral and cellular response to (+)-3,4-methylenedioxymethamphetamine [(+)-MDMA]. Drug and Alcohol Dependence. 81: 117-27. PMID 16054778 DOI: 10.1016/J.Drugalcdep.2005.06.004 |
0.827 |
|
| 2005 |
Szucs RP, Frankel PS, McMahon LR, Cunningham KA. Relationship of cocaine-induced c-Fos expression to behaviors and the role of serotonin 5-HT2A receptors in cocaine-induced c-Fos expression. Behavioral Neuroscience. 119: 1173-83. PMID 16300424 DOI: 10.1037/0735-7044.119.5.1173 |
0.804 |
|
| 2005 |
Bubar MJ, Seitz PK, Thomas ML, Cunningham KA. Validation of a selective serotonin 5-HT(2C) receptor antibody for utilization in fluorescence immunohistochemistry studies. Brain Research. 1063: 105-13. PMID 16274677 DOI: 10.1016/J.Brainres.2005.09.050 |
0.787 |
|
| 2005 |
Sell SL, Dillon AM, Cunningham KA, Thomas ML. Estrous cycle influence on individual differences in the response to novelty and cocaine in female rats. Behavioural Brain Research. 161: 69-74. PMID 15904711 DOI: 10.1016/J.Bbr.2005.01.004 |
0.739 |
|
| 2005 |
Herin DV, Liu S, Ullrich T, Rice KC, Cunningham KA. Role of the serotonin 5-HT2A receptor in the hyperlocomotive and hyperthermic effects of (+)-3,4-methylenedioxymethamphetamine. Psychopharmacology. 178: 505-13. PMID 15765263 DOI: 10.1007/S00213-004-2030-4 |
0.812 |
|
| 2005 |
Cunningham K, Bubar M, Brooks R, Seitz P, Thomas M. S31 BEHAVIORAL AND NEURAL ADAPTATIONS DURING WITHDRAWAL FROM A NON-NEUROTOXIC REGIMEN OF (+)-3,4-METHYLENEDIOXYMETHAMPHETAMINE [(+)-MDMA; ECSTASY] Behavioural Pharmacology. 16: S10. DOI: 10.1097/00008877-200509001-00031 |
0.714 |
|
| 2004 |
Cunningham KA. Aggression upon adolescent cocaine exposure linked to serotonin anomalies: theoretical comment on Ricci et al. (2004). Behavioral Neuroscience. 118: 1143-4. PMID 15506900 DOI: 10.1037/0735-7044.118.5.1143 |
0.416 |
|
| 2004 |
Koldzic-Zivanovic N, Seitz PK, Watson CS, Cunningham KA, Thomas ML. Intracellular signaling involved in estrogen regulation of serotonin reuptake. Molecular and Cellular Endocrinology. 226: 33-42. PMID 15489003 DOI: 10.1016/J.Mce.2004.07.017 |
0.356 |
|
| 2004 |
Filip M, Bubar MJ, Cunningham KA. Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. The Journal of Pharmacology and Experimental Therapeutics. 310: 1246-54. PMID 15131246 DOI: 10.1124/Jpet.104.068841 |
0.815 |
|
| 2004 |
Bubar MJ, Pack KM, Frankel PS, Cunningham KA. Effects of dopamine D1- or D2-like receptor antagonists on the hypermotive and discriminative stimulus effects of (+)-MDMA. Psychopharmacology. 173: 326-36. PMID 15064911 DOI: 10.1007/S00213-004-1790-1 |
0.781 |
|
| 2004 |
Frankel PS, Cunningham KA. m-Chlorophenylpiperazine (mCPP) modulates the discriminative stimulus effects of cocaine through actions at the 5-HT2C receptor. Behavioral Neuroscience. 118: 157-62. PMID 14979792 DOI: 10.1037/0735-7044.118.1.157 |
0.496 |
|
| 2003 |
McMahon LR, Cunningham KA. Discriminative stimulus effects of (-)-ephedrine in rats: analysis with catecholamine transporter and receptor ligands. Drug and Alcohol Dependence. 70: 255-64. PMID 12757963 DOI: 10.1016/S0376-8716(03)00011-5 |
0.6 |
|
| 2003 |
Filip M, Cunningham KA. Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex. The Journal of Pharmacology and Experimental Therapeutics. 306: 734-43. PMID 12721337 DOI: 10.1124/Jpet.102.045716 |
0.528 |
|
| 2003 |
McCreary AC, Filip M, Cunningham KA. Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes. Behavioral Neuroscience. 117: 212-21. PMID 12708517 DOI: 10.1037/0735-7044.117.2.212 |
0.508 |
|
| 2003 |
Zhou W, Cunningham KA, Thomas ML. Estrogen effects on the hyperactivity induced by (+)-MDMA and cocaine in female rats. Behavioral Neuroscience. 117: 84-94. PMID 12619911 DOI: 10.1037/0735-7044.117.1.84 |
0.479 |
|
| 2003 |
Bubar MJ, McMahon LR, De Deurwaerdère P, Spampinato U, Cunningham KA. Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens. Neuropharmacology. 44: 342-53. PMID 12604093 DOI: 10.1016/S0028-3908(02)00381-7 |
0.842 |
|
| 2003 |
Filip M, Cunningham K. P.5.039 Influence of serotonin 5-HT2A and 5 HT2C receptor agonists and antagonists on the locomotor and discriminative stimulus effects of cocaine or direct dopamine D1-like and D2-like receptor agonists European Neuropsychopharmacology. 13: S422-S423. DOI: 10.1016/S0924-977X(03)92288-7 |
0.361 |
|
| 2002 |
Frankel PS, Cunningham KA. The hallucinogen d-lysergic acid diethylamide (d-LSD) induces the immediate-early gene c-Fos in rat forebrain. Brain Research. 958: 251-60. PMID 12470860 DOI: 10.1016/S0006-8993(02)03548-5 |
0.32 |
|
| 2002 |
Sell SL, Thomas ML, Cunningham KA. Influence of estrous cycle and estradiol on behavioral sensitization to cocaine in female rats. Drug and Alcohol Dependence. 67: 281-90. PMID 12127199 DOI: 10.1016/S0376-8716(02)00085-6 |
0.765 |
|
| 2002 |
Zhou W, Cunningham KA, Thomas ML. Estrogen regulation of gene expression in the brain: a possible mechanism altering the response to psychostimulants in female rats. Brain Research. Molecular Brain Research. 100: 75-83. PMID 12008023 DOI: 10.1016/S0169-328X(02)00134-1 |
0.521 |
|
| 2002 |
Filip M, Cunningham KA. Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine. Pharmacology, Biochemistry, and Behavior. 71: 745-56. PMID 11888566 DOI: 10.1016/S0091-3057(01)00741-9 |
0.599 |
|
| 2002 |
Zhou W, Koldzic-Zivanovic N, Clarke CH, de Beun R, Wassermann K, Bury PS, Cunningham KA, Thomas ML. Selective estrogen receptor modulator effects in the rat brain. Neuroendocrinology. 75: 24-33. PMID 11810032 DOI: 10.1159/000048218 |
0.364 |
|
| 2002 |
Bankson MG, Cunningham KA. Pharmacological studies of the acute effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-HT(1B/1D) and 5-HT(2) receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 40-52. PMID 11751031 DOI: 10.1016/S0893-133X(01)00345-1 |
0.83 |
|
| 2001 |
McMahon LR, Filip M, Cunningham KA. Differential regulation of the mesoaccumbens circuit by serotonin 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7781-7. PMID 11567068 DOI: 10.1523/Jneurosci.21-19-07781.2001 |
0.733 |
|
| 2001 |
Bankson MG, Cunningham KA. 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions. The Journal of Pharmacology and Experimental Therapeutics. 297: 846-52. PMID 11356903 |
0.827 |
|
| 2001 |
McMahon LR, Cunningham KA. Antagonism of 5-hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 357-63. PMID 11259563 |
0.718 |
|
| 2001 |
McMahon LR, Cunningham KA. Role of 5-HT(2a) and 5-HT(2B/2C) receptors in the behavioral interactions between serotonin and catecholamine reuptake inhibitors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 319-29. PMID 11166521 DOI: 10.1016/S0893-133X(00)00206-2 |
0.708 |
|
| 2000 |
Filip M, Thomas ML, Cunningham KA. Dopamine D5 receptors in nucleus accumbens contribute to the detection of cocaine in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC98. PMID 11000198 |
0.349 |
|
| 2000 |
Sell SL, Scalzitti JM, Thomas ML, Cunningham KA. Influence of ovarian hormones and estrous cycle on the behavioral response to cocaine in female rats. The Journal of Pharmacology and Experimental Therapeutics. 293: 879-86. PMID 10869388 |
0.753 |
|
| 2000 |
De La Garza R, Cunningham KA. The effects of the 5-hydroxytryptamine(1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin on spontaneous activity, cocaine-induced hyperactivity and behavioral sensitization: a microanalysis of locomotor activity. The Journal of Pharmacology and Experimental Therapeutics. 292: 610-7. PMID 10640298 |
0.402 |
|
| 1999 |
McMahon LR, Cunningham KA. Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. The Journal of Pharmacology and Experimental Therapeutics. 291: 300-7. PMID 10490917 |
0.725 |
|
| 1999 |
McCreary AC, Bankson MG, Cunningham KA. Pharmacological studies of the acute and chronic effects of (+)-3, 4-methylenedioxymethamphetamine on locomotor activity: role of 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B/1D) receptors. The Journal of Pharmacology and Experimental Therapeutics. 290: 965-73. PMID 10454466 |
0.826 |
|
| 1999 |
McCreary AC, Cunningham KA. Effects of the 5-HT2C/2B antagonist SB 206553 on hyperactivity induced by cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 556-64. PMID 10327425 DOI: 10.1016/S0893-133X(98)00087-6 |
0.543 |
|
| 1998 |
De La Garza R, Callahan PM, Cunningham KA. The discriminative stimulus properties of cocaine: effects of microinfusion of cocaine, a 5-HT1A agonist or antagonist, into the ventral tegmental area. Psychopharmacology. 137: 1-6. PMID 9631950 DOI: 10.1007/S002130050586 |
0.533 |
|
| 1998 |
Cunningham KA. COCAINE PHARMACOTHERAPY Behavioural Pharmacology. 9: S107. DOI: 10.1097/00008877-199808000-00247 |
0.324 |
|
| 1997 |
Callahan PM, De La Garza R, Cunningham KA. Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems. Pharmacology, Biochemistry, and Behavior. 57: 601-7. PMID 9218282 DOI: 10.1016/S0091-3057(96)00434-0 |
0.481 |
|
| 1997 |
Callahan PM, Cunningham KA. Modulation of the discriminative stimulus properties of cocaine: comparison of the effects of fluoxetine with 5-HT1A and 5-HT1B receptor agonists. Neuropharmacology. 36: 373-81. PMID 9175616 DOI: 10.1016/S0028-3908(97)00010-5 |
0.544 |
|
| 1997 |
Walsh SL, Cunningham KA. Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology. 130: 41-58. PMID 9089847 DOI: 10.1007/S002130050210 |
0.566 |
|
| 1996 |
Cunningham KA, Henriksen SJ, Paris JM, Williams JT, White FJ. Electrophysical analyses of psychostimulant drug actions: from the slice to the awake animal. Nida Research Monograph. 162: 76-8. PMID 9066820 |
0.462 |
|
| 1996 |
Cunningham KA, Bradberry CW, Chang AS, Reith ME. The role of serotonin in the actions of psychostimulants: molecular and pharmacological analyses. Behavioural Brain Research. 73: 93-102. PMID 8788484 DOI: 10.1016/0166-4328(96)00077-0 |
0.559 |
|
| 1996 |
De La Garza R, Callahan PM, Cunningham KA. Detailed investigations of 5-HT3 compounds in a drug discrimination model. Pharmacology, Biochemistry, and Behavior. 54: 533-40. PMID 8743626 DOI: 10.1016/0091-3057(95)02207-4 |
0.59 |
|
| 1996 |
CUNNINGHAM KA, CALLAHAN PM, DE LA GARZA RI. LIMBIC CIRCUITRY AND NEUROTRANSMITTERS INVOLVED IN THE DISCRIMINATIVE PROPERTIES OF COCAINE Behavioural Pharmacology. 7: 22. DOI: 10.1097/00008877-199605001-00048 |
0.445 |
|
| 1996 |
Cunningham K, De La Garza R, Windh R. The integrity of serotonin function and sensitization to cocaine European Neuropsychopharmacology. 6: 161. DOI: 10.1016/0924-977X(96)88049-7 |
0.465 |
|
| 1995 |
Callahan PM, Bryan SK, Cunningham KA. Discriminative stimulus effects of cocaine: antagonism by dopamine D1 receptor blockade in the amygdala. Pharmacology, Biochemistry, and Behavior. 51: 759-66. PMID 7675856 DOI: 10.1016/0091-3057(95)00027-T |
0.496 |
|
| 1995 |
Callahan PM, Cunningham KA. Modulation of the discriminative stimulus properties of cocaine by 5-HT1B and 5-HT2C receptors. The Journal of Pharmacology and Experimental Therapeutics. 274: 1414-24. PMID 7562516 |
0.418 |
|
| 1994 |
Cunningham KA, Callahan PM. Neurobehavioral pharmacology of cocaine: role for serotonin in its locomotor and discriminative stimulus effects. Nida Research Monograph. 145: 40-66. PMID 8742807 |
0.4 |
|
| 1994 |
Callahan PM, Cunningham KA. Involvement of 5-HT2C receptors in mediating the discriminative stimulus properties of m-chlorophenylpiperazine (mCPP). European Journal of Pharmacology. 257: 27-38. PMID 8082704 DOI: 10.1016/0014-2999(94)90690-4 |
0.499 |
|
| 1994 |
Callahan PM, De La Garza R, Cunningham KA. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. 115: 110-4. PMID 7862881 DOI: 10.1007/Bf02244759 |
0.499 |
|
| 1994 |
Paris JM, Cunningham KA. Habenula lesions decrease the responsiveness of dorsal raphe serotonin neurons to cocaine. Pharmacology, Biochemistry, and Behavior. 49: 555-60. PMID 7862707 DOI: 10.1016/0091-3057(94)90068-X |
0.523 |
|
| 1993 |
Callahan PM, Cunningham KA. Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats. The Journal of Pharmacology and Experimental Therapeutics. 266: 585-92. PMID 8355192 |
0.379 |
|
| 1993 |
Callahan PM, Cunningham KA. Attenuation of the interoceptive ('subjective') effects of cocaine by the novel antidepressant trazodone: Possible therapeutic efficacy in cocaine abuse? Nida Research Monograph Series. 252. |
0.336 |
|
| 1992 |
Callahan PM, Piercey MF, Cunningham KA. Effects of the putative dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 on the discriminative stimulus properties of cocaine. Psychopharmacology. 107: 73-7. PMID 1589564 DOI: 10.1007/Bf02244968 |
0.478 |
|
| 1992 |
Kozikowski AP, Roberti M, Xiang L, Bergmann JS, Callahan PM, Cunningham KA, Johnson KM. Structure-activity relationship studies of cocaine: replacement of the C-2 ester group by vinyl argues against H-bonding and provides an esterase-resistant, high-affinity cocaine analogue. Journal of Medicinal Chemistry. 35: 4764-6. PMID 1469704 DOI: 10.1021/Jm00103A015 |
0.413 |
|
| 1992 |
Cunningham KA, Paris JM, Goeders NE. Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse (New York, N.Y.). 11: 112-23. PMID 1385662 DOI: 10.1002/Syn.890110204 |
0.586 |
|
| 1992 |
Paris JM, Cunningham KA. Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA). Brain Research Bulletin. 28: 115-9. PMID 1347247 DOI: 10.1016/0361-9230(92)90237-R |
0.469 |
|
| 1992 |
Cunningham KA, Paris JM, Goeders NE. Serotonin neurotransmission in cocaine sensitization. Annals of the New York Academy of Sciences. 654: 117-27. PMID 1321571 DOI: 10.1111/J.1749-6632.1992.Tb25960.X |
0.492 |
|
| 1991 |
Callahan PM, Appel JB, Cunningham KA. Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psychopharmacology. 103: 50-5. PMID 2006243 DOI: 10.1007/Bf02244073 |
0.578 |
|
| 1991 |
Lee MA, Paris JM, Cunningham KA. Cocaine-induced behavioral sensitization is not associated with loss of GABA-immunoreactive neurons in the amygdala. Brain Research. 545: 351-4. PMID 1860058 DOI: 10.1016/0006-8993(91)91313-P |
0.431 |
|
| 1991 |
Cunningham KA, Callahan PM. Monoamine reuptake inhibitors enhance the discriminative state induced by cocaine in the rat. Psychopharmacology. 104: 177-80. PMID 1831559 DOI: 10.1007/Bf02244175 |
0.516 |
|
| 1991 |
Paris JM, Callahan PM, Lee JM, Cunningham KA. Behavioral sensitization to cocaine is not associated with changes in serotonin (5-HT) fiber immunoreactivity in rat forebrain. Brain Research Bulletin. 27: 843-7. PMID 1786564 DOI: 10.1016/0361-9230(91)90220-E |
0.562 |
|
| 1991 |
Paris JM, Cunningham KA. Serotonin 5-HT3 antagonists do not alter the discriminative stimulus properties of cocaine. Psychopharmacology. 104: 475-8. PMID 1780417 DOI: 10.1007/BF02245652 |
0.51 |
|
| 1991 |
Cunningham KA, Callahan PM. Neural mediators of the discriminative stimulus effects of cocaine Pharmacology Biochemistry and Behavior. 39: 236-237. DOI: 10.1016/0091-3057(91)90479-L |
0.42 |
|
| 1990 |
Cunningham KA, Lakoski JM. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 41-50. PMID 2137698 |
0.512 |
|
| 1990 |
Callahan PM, Cunningham KA. The discriminative stimulus properties of cocaine: effects of BAY K 8644 and nimodipine. European Journal of Pharmacology. 186: 143-7. PMID 1704310 DOI: 10.1016/0014-2999(90)94072-6 |
0.458 |
|
| 1988 |
Cunningham KA, Lakoski JM. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. European Journal of Pharmacology. 148: 457-62. PMID 3384007 DOI: 10.1016/0014-2999(88)90128-8 |
0.554 |
|
| 1988 |
Appel JB, Weathersby RT, Cunningham KA, Callahan PM, Barrett RL. Stimulus properties of dopaminergic drugs: comparisons involving selective agonists and antagonists. Psychopharmacology Series. 4: 44-56. PMID 3293045 |
0.58 |
|
| 1988 |
Lakoski JM, Cunningham KA. Cocaine interaction with central monoaminergic systems: electrophysiological approaches. Trends in Pharmacological Sciences. 9: 177-80. PMID 3073549 DOI: 10.1016/0165-6147(88)90034-X |
0.492 |
|
| 1987 |
Cunningham KA, Callahan PM, Appel JB. Discriminative stimulus properties of lisuride revisited: involvement of dopamine D2 receptors. The Journal of Pharmacology and Experimental Therapeutics. 241: 147-51. PMID 3553537 |
0.487 |
|
| 1987 |
Cunningham KA, Appel JB. Neuropharmacological reassessment of the discriminative stimulus properties of d-lysergic acid diethylamide (LSD). Psychopharmacology. 91: 67-73. PMID 3103161 DOI: 10.1007/BF00690929 |
0.573 |
|
| 1987 |
Cunningham KA, Callahan PM, Appel JB. Discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OHDPAT): implications for understanding the actions of novel anxiolytics. European Journal of Pharmacology. 138: 29-36. PMID 2887435 DOI: 10.1016/0014-2999(87)90333-5 |
0.632 |
|
| 1986 |
Appel JB, Cunningham KA. The use of drug discrimination procedures to characterize hallucinogenic drug actions. Psychopharmacology Bulletin. 22: 959-67. PMID 3797596 |
0.362 |
|
| 1986 |
Cunningham KA, Callahan PM, Appel JB. Discriminative stimulus properties of the serotonin agonist MK 212. Psychopharmacology. 90: 193-7. PMID 3097699 DOI: 10.1007/BF00181240 |
0.583 |
|
| 1986 |
Cunningham KA, Carroll BA, Appel JB. Effects of repeated administration of the monoamine oxidase inhibitor phenelzine on the discriminability of d-lysergic acid diethylamide (LSD) and 1-(m-trifluoromethylphenyl) piperazine (TFMPP). Psychopharmacology. 89: 134-5. PMID 3090587 DOI: 10.1007/BF00175206 |
0.479 |
|
| 1986 |
Cunningham KA, Appel JB. Possible 5-hydroxytryptamine1 (5-HT1) receptor involvement in the stimulus properties of 1-(m-trifluoromethylphenyl)piperazine (TFMPP). The Journal of Pharmacology and Experimental Therapeutics. 237: 369-77. PMID 2939233 |
0.572 |
|
| 1985 |
Cunningham KA, Callahan PM, Appel JB. Differentiation between the stimulus effects of l-5-hydroxytryptophan and LSD. European Journal of Pharmacology. 108: 179-86. PMID 3156756 DOI: 10.1016/0014-2999(85)90723-X |
0.541 |
|
| 1985 |
Cunningham KA, Callahan PM, Appel JB. Dopamine D1 receptor mediation of the discriminative stimulus properties of SKF 38393. European Journal of Pharmacology. 119: 121-5. PMID 2935415 DOI: 10.1016/0014-2999(85)90330-9 |
0.475 |
|
| 1985 |
Nielsen EB, Ginn SR, Cunningham KA, Appel JB. Antagonism of the LSD cue by putative serotonin antagonists: relationship to inhibition of in vivo [3H]spiroperidol binding. Behavioural Brain Research. 16: 171-6. PMID 2931089 DOI: 10.1016/0166-4328(85)90090-7 |
0.525 |
|
| 1985 |
Cunningham KA, Callahan PM, Craigmyle NA, Appel JB. Discriminative stimulus properties of clonidine: substitution by ergot derivatives. European Journal of Pharmacology. 119: 225-9. PMID 2868902 DOI: 10.1016/0014-2999(85)90299-7 |
0.441 |
|
| 1985 |
Appel JB, Cunningham KA, West KB. Monoaminergic involvement in the behavioral effects of ergot derivatives. Progress in Clinical and Biological Research. 192: 51-62. PMID 2867556 |
0.457 |
|
| 1984 |
Cunningham KA, Callahan PM, Appel JB. Discriminative stimulus properties of lergotrile. The Journal of Pharmacology and Experimental Therapeutics. 230: 47-52. PMID 6146709 |
0.566 |
|
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