| Year |
Citation |
Score |
| 2020 |
Niss K, Gomez-Casado C, Hjaltelin JX, Joeris T, Agace WW, Belling KG, Brunak S. Complete Topological Mapping of a Cellular Protein Interactome Reveals Bow-Tie Motifs as Ubiquitous Connectors of Protein Complexes. Cell Reports. 31: 107763. PMID 32553166 DOI: 10.1016/J.Celrep.2020.107763 |
0.328 |
|
| 2019 |
Saunders G, Baudis M, Becker R, Beltran S, Béroud C, Birney E, Brooksbank C, Brunak S, Van den Bulcke M, Drysdale R, Capella-Gutierrez S, Flicek P, Florindi F, Goodhand P, Gut I, et al. Leveraging European infrastructures to access 1 million human genomes by 2022. Nature Reviews. Genetics. PMID 31455890 DOI: 10.1038/S41576-019-0156-9 |
0.316 |
|
| 2019 |
Hjaltelin JX, Izarzugaza JMG, Jensen LJ, Russo F, Westergaard D, Brunak S. Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types. Npj Systems Biology and Applications. 5: 27. PMID 31396397 DOI: 10.1038/s41540-019-0104-5 |
0.47 |
|
| 2019 |
Gådin JR, Buil A, Colantuoni C, Jaffe AE, Nielsen J, Shin JH, Hyde TM, Kleinman JE, Plath N, Eriksson P, Brunak S, Didriksen M, Weinberger DR, Folkersen L. Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq. Plos One. 14: e0217765. PMID 31206532 DOI: 10.1371/Journal.Pone.0217765 |
0.302 |
|
| 2019 |
Nielsen H, Tsirigos KD, Brunak S, von Heijne G. A Brief History of Protein Sorting Prediction. The Protein Journal. PMID 31119599 DOI: 10.1007/S10930-019-09838-3 |
0.313 |
|
| 2019 |
Aguayo-Orozco A, Taboureau O, Brunak S. The use of systems biology in chemical risk assessment Current Opinion in Toxicology. 15: 48-54. DOI: 10.1016/J.Cotox.2019.03.003 |
0.306 |
|
| 2018 |
Pedersen HK, Forslund SK, Gudmundsdottir V, Petersen AØ, Hildebrand F, Hyötyläinen T, Nielsen T, Hansen T, Bork P, Ehrlich SD, Brunak S, Oresic M, Pedersen O, Nielsen HB. A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links. Nature Protocols. PMID 30382244 DOI: 10.1038/S41596-018-0064-Z |
0.489 |
|
| 2018 |
Fenoy E, Izarzugaza JMG, Jurtz V, Brunak S, Nielsen M. A generic Deep Convolutional Neural Network framework for prediction of Receptor-ligand Interactions. NetPhosPan; Application to Kinase Phosphorylation prediction. Bioinformatics (Oxford, England). PMID 30169744 DOI: 10.1093/Bioinformatics/Bty715 |
0.317 |
|
| 2018 |
Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, et al. Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers. Oncotarget. 9: 31018-31031. PMID 30123424 DOI: 10.18632/Oncotarget.25760 |
0.307 |
|
| 2018 |
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, et al. Unexplored therapeutic opportunities in the human genome. Nature Reviews. Drug Discovery. PMID 29567993 DOI: 10.1038/Nrd.2018.52 |
0.504 |
|
| 2018 |
Jensen KH, Izarzugaza JMG, Juncker AS, Hansen RB, Hansen TF, Timshel P, Blondal T, Jensen TS, Rygaard-Hjalsted E, Mouritzen P, Thorsen M, Wernersson R, Nielsen HB, Jakobsen A, Brunak S, et al. Analysis of a gene panel for targeted sequencing of colorectal cancer samples. Oncotarget. 9: 9043-9060. PMID 29507673 DOI: 10.18632/Oncotarget.24138 |
0.308 |
|
| 2018 |
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, et al. Unexplored therapeutic opportunities in the human genome. Nature Reviews. Drug Discovery. PMID 29472638 DOI: 10.1038/Nrd.2018.14 |
0.56 |
|
| 2018 |
Vanlandewijck M, Dadras MS, Lomnytska M, Mahzabin T, Lee Miller M, Busch C, Brunak S, Heldin CH, Moustakas A. The protein kinase SIK downregulates the polarity protein Par3. Oncotarget. 9: 5716-5735. PMID 29464029 DOI: 10.18632/Oncotarget.23788 |
0.314 |
|
| 2018 |
Westergaard D, Stærfeldt HH, Tønsberg C, Jensen LJ, Brunak S. A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts. Plos Computational Biology. 14: e1005962. PMID 29447159 DOI: 10.1371/Journal.Pcbi.1005962 |
0.52 |
|
| 2018 |
Gudmundsdottir V, Pedersen HK, Allebrandt KV, Brorsson C, van Leeuwen N, Banasik K, Mahajan A, Groves CJ, van de Bunt M, Dawed AY, Fritsche A, Staiger H, Simonis-Bik AMC, Deelen J, Kramer MHH, ... ... Brunak S, et al. Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study. Plos One. 13: e0189886. PMID 29293525 DOI: 10.1371/Journal.Pone.0189886 |
0.307 |
|
| 2017 |
Russo F, Di Bella S, Vannini F, Berti G, Scoyni F, Cook HV, Santos A, Nigita G, Bonnici V, Laganà A, Geraci F, Pulvirenti A, Giugno R, De Masi F, Belling K, ... ... Brunak SR, et al. miRandola 2017: a curated knowledge base of non-invasive biomarkers. Nucleic Acids Research. PMID 29036351 DOI: 10.1093/Nar/Gkx854 |
0.504 |
|
| 2017 |
Kirk IK, Weinhold N, Brunak S, Belling K. The impact of the protein interactome on the syntenic structure of mammalian genomes. Plos One. 12: e0179112. PMID 28910296 DOI: 10.1371/Journal.Pone.0179112 |
0.37 |
|
| 2017 |
Maretty L, Jensen JM, Petersen B, Sibbesen JA, Liu S, Villesen P, Skov L, Belling K, Theil Have C, Izarzugaza JMG, Grosjean M, Bork-Jensen J, Grove J, Als TD, Huang S, ... ... Brunak S, et al. Sequencing and de novo assembly of 150 genomes from Denmark as a population reference. Nature. PMID 28746312 DOI: 10.1038/Nature23264 |
0.326 |
|
| 2017 |
Pedersen HK, Gudmundsdottir V, Brunak S. Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes. Frontiers in Genetics. 8: 43. PMID 28473845 DOI: 10.3389/Fgene.2017.00043 |
0.358 |
|
| 2017 |
Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Pedersen HK, Arumugam M, Kristiansen K, Voigt AY, Vestergaard H, Hercog R, ... ... Brunak S, et al. Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature. 545: 116. PMID 28470190 DOI: 10.1038/Nature22318 |
0.451 |
|
| 2017 |
Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S. Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity. Human Molecular Genetics. PMID 28369266 DOI: 10.1093/Hmg/Ddx014 |
0.348 |
|
| 2017 |
Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge RJ, Frånberg M, Sennblad B, Baldassarre D, Veglia F, Humphries SE, Rauramaa R, de Faire U, Smit AJ, Giral P, Kurl S, Mannarino E, ... ... Brunak S, et al. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. Plos Genetics. 13: e1006706. PMID 28369058 DOI: 10.1371/Journal.Pgen.1006706 |
0.351 |
|
| 2017 |
Francavilla C, Lupia M, Tsafou K, Villa A, Kowalczyk K, Rakownikow Jersie-Christensen R, Bertalot G, Confalonieri S, Brunak S, Jensen LJ, Cavallaro U, Olsen JV. Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer. Cell Reports. 18: 3242-3256. PMID 28355574 DOI: 10.1016/J.Celrep.2017.03.015 |
0.498 |
|
| 2017 |
Kirk IK, Weinhold N, Belling K, Skakkebæk NE, Jensen TS, Leffers H, Juul A, Brunak S. Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations. Cell Systems. PMID 28215527 DOI: 10.1016/J.Cels.2017.01.001 |
0.349 |
|
| 2016 |
Nguyen DT, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, Hersey A, Holmes J, Jensen LJ, Karlsson A, Liu G, Ma'ayan A, Mandava G, Mani S, Mehta S, et al. Pharos: Collating protein information to shed light on the druggable genome. Nucleic Acids Research. PMID 27903890 DOI: 10.1093/Nar/Gkw1072 |
0.547 |
|
| 2016 |
Li T, Wernersson R, Hansen RB, Horn H, Mercer J, Slodkowicz G, Workman CT, Rigina O, Rapacki K, Stærfeldt HH, Brunak S, Jensen TS, Lage K. A scored human protein-protein interaction network to catalyze genomic interpretation. Nature Methods. PMID 27892958 DOI: 10.1038/Nmeth.4083 |
0.363 |
|
| 2016 |
Plichta DR, Juncker AS, Bertalan M, Rettedal E, Gautier L, Varela E, Manichanh C, Fouqueray C, Levenez F, Nielsen T, Doré J, Machado AM, de Evgrafov MC, Hansen T, Jørgensen T, ... ... Brunak S, et al. Transcriptional interactions suggest niche segregation among microorganisms in the human gut. Nature Microbiology. 1: 16152. PMID 27564131 DOI: 10.1038/Nmicrobiol.2016.152 |
0.44 |
|
| 2016 |
Hu JX, Thomas CE, Brunak S. Network biology concepts in complex disease comorbidities. Nature Reviews. Genetics. PMID 27498692 DOI: 10.1038/Nrg.2016.87 |
0.3 |
|
| 2016 |
Pedersen HK, Gudmundsdottir V, Nielsen HB, Hyotylainen T, Nielsen T, Jensen BA, Forslund K, Hildebrand F, Prifti E, Falony G, Le Chatelier E, Levenez F, Doré J, Mattila I, Plichta DR, ... ... Brunak S, et al. Human gut microbes impact host serum metabolome and insulin sensitivity. Nature. PMID 27409811 DOI: 10.1038/Nature18646 |
0.416 |
|
| 2016 |
Pons T, Vazquez M, Matey-Hernandez ML, Brunak S, Valencia A, Izarzugaza JM. KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily. Bmc Genomics. 17: 396. PMID 27357839 DOI: 10.1186/S12864-016-2723-1 |
0.359 |
|
| 2016 |
Friis-Nielsen J, Kjartansdóttir KR, Mollerup S, Asplund M, Mourier T, Jensen RH, Hansen TA, Rey-Iglesia A, Richter SR, Nielsen IB, Alquezar-Planas DE, Olsen PV, Vinner L, Fridholm H, Nielsen LP, ... ... Brunak S, et al. Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers. Viruses. 8. PMID 26907326 DOI: 10.3390/v8020053 |
0.332 |
|
| 2016 |
Kringelum J, Kjaerulff SK, Brunak S, Lund O, Oprea TI, Taboureau O. ChemProt-3.0: a global chemical biology diseases mapping. Database : the Journal of Biological Databases and Curation. 2016. PMID 26876982 DOI: 10.1093/Database/Bav123 |
0.335 |
|
| 2015 |
Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Krogh Pedersen H, Arumugam M, Kristiansen K, Yvonne Voigt A, Vestergaard H, Hercog R, ... ... Brunak S, et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature. PMID 26633628 DOI: 10.1038/Nature15766 |
0.46 |
|
| 2015 |
Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Krogh Pedersen H, Arumugam M, Kristiansen K, Yvonne Voigt A, Vestergaard H, Hercog R, ... ... Brunak S, et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature. PMID 26618873 DOI: 10.1038/nature15766 |
0.33 |
|
| 2015 |
Vazquez M, Pons T, Brunak S, Valencia A, Izarzugaza JM. wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases. Human Mutation. PMID 26443060 DOI: 10.1002/Humu.22914 |
0.374 |
|
| 2015 |
Vinner L, Mourier T, Friis-Nielsen J, Gniadecki R, Dybkaer K, Rosenberg J, Langhoff JL, Cruz DF, Fonager J, Izarzugaza JM, Gupta R, Sicheritz-Ponten T, Brunak S, Willerslev E, Nielsen LP, et al. Investigation of Human Cancers for Retrovirus by Low-Stringency Target Enrichment and High-Throughput Sequencing. Scientific Reports. 5: 13201. PMID 26285800 DOI: 10.1038/Srep13201 |
0.315 |
|
| 2015 |
Warrer P, Jensen PB, Aagaard L, Jensen LJ, Brunak S, Krag MH, Rossing P, Almdal T, Andersen HU, Hansen EH. Identification of possible adverse drug reactions in clinical notes: The case of glucose-lowering medicines. Journal of Research in Pharmacy Practice. 4: 64-72. PMID 25984543 DOI: 10.4103/2279-042X.155753 |
0.499 |
|
| 2015 |
Besenbacher S, Liu S, Izarzugaza JM, Grove J, Belling K, Bork-Jensen J, Huang S, Als TD, Li S, Yadav R, Rubio-García A, Lescai F, Demontis D, Rao J, Ye W, ... ... Brunak S, et al. Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. Nature Communications. 6: 5969. PMID 25597990 DOI: 10.1038/Ncomms6969 |
0.303 |
|
| 2014 |
Eriksson R, Aagaard L, Jensen LJ, Borisova L, Hørlück D, Brunak S, Hansen EH. Discrepancies in listed adverse drug reactions in pharmaceutical product information supplied by the regulatory authorities in Denmark and the USA. Pharmacology Research & Perspectives. 2: e00038. PMID 25505588 DOI: 10.1002/Prp2.38 |
0.484 |
|
| 2014 |
Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, et al. Modules, networks and systems medicine for understanding disease and aiding diagnosis. Genome Medicine. 6: 82. PMID 25473422 DOI: 10.1186/S13073-014-0082-6 |
0.326 |
|
| 2014 |
Malaspinas AS, Lao O, Schroeder H, Rasmussen M, Raghavan M, Moltke I, Campos PF, Sagredo FS, Rasmussen S, Gonçalves VF, Albrechtsen A, Allentoft ME, Johnson PL, Li M, Reis S, ... ... Brunak S, et al. Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil. Current Biology : Cb. 24: R1035-7. PMID 25455029 DOI: 10.1016/J.Cub.2014.09.078 |
0.313 |
|
| 2014 |
Re A, Workman CT, Waldron L, Quattrone A, Brunak S. Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells. Stem Cell Research. 13: 316-28. PMID 25173649 DOI: 10.1016/J.Scr.2014.07.008 |
0.33 |
|
| 2014 |
Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sunagawa S, Plichta DR, Gautier L, Pedersen AG, Le Chatelier E, Pelletier E, Bonde I, Nielsen T, Manichanh C, Arumugam M, ... ... Brunak S, et al. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes. Nature Biotechnology. 32: 822-8. PMID 24997787 DOI: 10.1038/Nbt.2939 |
0.494 |
|
| 2014 |
Li J, Jia H, Cai X, Zhong H, Feng Q, Sunagawa S, Arumugam M, Kultima JR, Prifti E, Nielsen T, Juncker AS, Manichanh C, Chen B, Zhang W, Levenez F, ... ... Brunak S, et al. An integrated catalog of reference genes in the human gut microbiome. Nature Biotechnology. 32: 834-41. PMID 24997786 DOI: 10.1038/Nbt.2942 |
0.505 |
|
| 2014 |
Jensen AB, Moseley PL, Oprea TI, Ellesøe SG, Eriksson R, Schmock H, Jensen PB, Jensen LJ, Brunak S. Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients. Nature Communications. 5: 4022. PMID 24959948 DOI: 10.1038/Ncomms5022 |
0.491 |
|
| 2014 |
Lundby A, Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C, Pfeufer A, Lynch SN, Olesen SP, Brunak S, Ellinor PT, Jukema JW, Trompet S, Ford I, Macfarlane PW, et al. Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nature Methods. 11: 868-74. PMID 24952909 DOI: 10.1038/Nmeth.2997 |
0.323 |
|
| 2014 |
Eriksson R, Werge T, Jensen LJ, Brunak S. Dose-specific adverse drug reaction identification in electronic patient records: temporal data mining in an inpatient psychiatric population. Drug Safety. 37: 237-47. PMID 24634163 DOI: 10.1007/S40264-014-0145-Z |
0.507 |
|
| 2014 |
Geertz-Hansen HM, Blom N, Feist AM, Brunak S, Petersen TN. Cofactory: sequence-based prediction of cofactor specificity of Rossmann folds. Proteins. 82: 1819-28. PMID 24523134 DOI: 10.1002/Prot.24536 |
0.302 |
|
| 2014 |
Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, Mende DR, Fernandes GR, Tap J, Bruls T, Batto J, Bertalan M, Borruel N, Casellas F, Fernandez L, Gautier L, ... ... Brunak S, et al. Addendum: Enterotypes of the human gut microbiome Nature. 506: 516-516. DOI: 10.1038/Nature13075 |
0.413 |
|
| 2013 |
Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, ... ... Brunak S, et al. Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes. American Journal of Human Genetics. 93: 1072-86. PMID 24290377 DOI: 10.1016/J.Ajhg.2013.11.005 |
0.309 |
|
| 2013 |
Sunagawa S, Mende DR, Zeller G, Izquierdo-Carrasco F, Berger SA, Kultima JR, Coelho LP, Arumugam M, Tap J, Nielsen HB, Rasmussen S, Brunak S, Pedersen O, Guarner F, de Vos WM, et al. Metagenomic species profiling using universal phylogenetic marker genes. Nature Methods. 10: 1196-9. PMID 24141494 DOI: 10.1038/Nmeth.2693 |
0.476 |
|
| 2013 |
Blair DR, Lyttle CS, Mortensen JM, Bearden CF, Jensen AB, Khiabanian H, Melamed R, Rabadan R, Bernstam EV, Brunak S, Jensen LJ, Nicolae D, Shah NH, Grossman RL, Cox NJ, et al. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Cell. 155: 70-80. PMID 24074861 DOI: 10.1016/J.Cell.2013.08.030 |
0.511 |
|
| 2013 |
Audouze K, Brunak S, Grandjean P. A computational approach to chemical etiologies of diabetes. Scientific Reports. 3: 2712. PMID 24048418 DOI: 10.1038/Srep02712 |
0.333 |
|
| 2013 |
Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, Almeida M, Arumugam M, Batto JM, Kennedy S, Leonard P, Li J, Burgdorf K, Grarup N, Jørgensen T, ... ... Brunak S, et al. Richness of human gut microbiome correlates with metabolic markers. Nature. 500: 541-6. PMID 23985870 DOI: 10.1038/Nature12506 |
0.423 |
|
| 2013 |
Johansen MB, Izarzugaza JM, Brunak S, Petersen TN, Gupta R. Prediction of disease causing non-synonymous SNPs by the Artificial Neural Network Predictor NetDiseaseSNP. Plos One. 8: e68370. PMID 23935863 DOI: 10.1371/Journal.Pone.0068370 |
0.312 |
|
| 2013 |
Börnigen D, Pers TH, Thorrez L, Huttenhower C, Moreau Y, Brunak S. Concordance of gene expression in human protein complexes reveals tissue specificity and pathology. Nucleic Acids Research. 41: e171. PMID 23921638 DOI: 10.1093/Nar/Gkt661 |
0.317 |
|
| 2013 |
Orlando L, Ginolhac A, Zhang G, Froese D, Albrechtsen A, Stiller M, Schubert M, Cappellini E, Petersen B, Moltke I, Johnson PL, Fumagalli M, Vilstrup JT, Raghavan M, Korneliussen T, ... ... Brunak S, et al. Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse. Nature. 499: 74-8. PMID 23803765 DOI: 10.1038/Nature12323 |
0.522 |
|
| 2013 |
Eriksson R, Jensen PB, Frankild S, Jensen LJ, Brunak S. Dictionary construction and identification of possible adverse drug events in Danish clinical narrative text. Journal of the American Medical Informatics Association : Jamia. 20: 947-53. PMID 23703825 DOI: 10.1136/Amiajnl-2013-001708 |
0.493 |
|
| 2013 |
Pers TH, Dworzy?ski P, Thomas CE, Lage K, Brunak S. MetaRanker 2.0: a web server for prioritization of genetic variation data. Nucleic Acids Research. 41: W104-8. PMID 23703204 DOI: 10.1093/Nar/Gkt387 |
0.344 |
|
| 2013 |
Edsgärd D, Dalgaard MD, Weinhold N, Wesolowska-Andersen A, Rajpert-De Meyts E, Ottesen AM, Juul A, Skakkebæk NE, Skøt Jensen T, Gupta R, Leffers H, Brunak S. Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer. Frontiers in Endocrinology. 4: 2. PMID 23372565 DOI: 10.3389/Fendo.2013.00002 |
0.324 |
|
| 2013 |
Jensen PB, Jensen LJ, Brunak S. Reply to 'Mining electronic health records: an additional perspective'. Nature Reviews. Genetics. 14: 75. PMID 23247438 DOI: 10.1038/Nrg3208-C2 |
0.452 |
|
| 2013 |
Kim Kjærulff S, Wich L, Kringelum J, Jacobsen UP, Kouskoumvekaki I, Audouze K, Lund O, Brunak S, Oprea TI, Taboureau O. ChemProt-2.0: visual navigation in a disease chemical biology database. Nucleic Acids Research. 41: D464-9. PMID 23185041 DOI: 10.1093/Nar/Gks1166 |
0.348 |
|
| 2012 |
Jensen PB, Jensen LJ, Brunak S. Mining electronic health records: towards better research applications and clinical care. Nature Reviews. Genetics. 13: 395-405. PMID 22549152 DOI: 10.1038/Nrg3208 |
0.496 |
|
| 2012 |
Rojas AM, Santamaria A, Malik R, Jensen TS, Körner R, Morilla I, de Juan D, Krallinger M, Hansen DA, Hoffmann R, Lees J, Reid A, Yeats C, Wehner A, Elowe S, ... ... Brunak S, et al. Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology. Plos One. 7: e31813. PMID 22427808 DOI: 10.1371/Journal.Pone.0031813 |
0.359 |
|
| 2012 |
Dalgaard MD, Weinhold N, Edsgärd D, Silver JD, Pers TH, Nielsen JE, Jørgensen N, Juul A, Gerds TA, Giwercman A, Giwercman YL, Cohn-Cedermark G, Virtanen HE, Toppari J, Daugaard G, ... ... Brunak S, et al. A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation. Journal of Medical Genetics. 49: 58-65. PMID 22140272 DOI: 10.1136/Jmedgenet-2011-100174 |
0.334 |
|
| 2011 |
Wang K, Wernersson R, Brunak S. The strength of intron donor splice sites in human genes displays a bell-shaped pattern. Bioinformatics (Oxford, England). 27: 3079-84. PMID 21994226 DOI: 10.1093/Bioinformatics/Btr532 |
0.311 |
|
| 2011 |
Roque FS, Jensen PB, Schmock H, Dalgaard M, Andreatta M, Hansen T, Søeby K, Bredkjær S, Juul A, Werge T, Jensen LJ, Brunak S. Using electronic patient records to discover disease correlations and stratify patient cohorts. Plos Computational Biology. 7: e1002141. PMID 21901084 DOI: 10.1371/Journal.Pcbi.1002141 |
0.504 |
|
| 2011 |
Jensen MK, Pers TH, Dworzynski P, Girman CJ, Brunak S, Rimm EB. Protein interaction-based genome-wide analysis of incident coronary heart disease. Circulation. Cardiovascular Genetics. 4: 549-56. PMID 21880673 DOI: 10.1161/Circgenetics.111.960393 |
0.353 |
|
| 2011 |
Berchtold LA, Størling ZM, Ortis F, Lage K, Bang-Berthelsen C, Bergholdt R, Hald J, Brorsson CA, Eizirik DL, Pociot F, Brunak S, Størling J. Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 108: E681-8. PMID 21705657 DOI: 10.1073/Pnas.1104384108 |
0.334 |
|
| 2011 |
Edsgärd D, Scheel M, Hansen NT, Ralfkiaer U, Jensen TS, Skakkebaek NE, Brunak S, Gupta R, Rajpert-De Meyts E, Ottesen AM. Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information. International Journal of Andrology. 34: e122-32. PMID 21696394 DOI: 10.1111/J.1365-2605.2011.01188.X |
0.31 |
|
| 2011 |
Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, Mende DR, Fernandes GR, Tap J, Bruls T, Batto JM, Bertalan M, Borruel N, Casellas F, Fernandez L, Gautier L, ... ... Brunak S, et al. Enterotypes of the human gut microbiome. Nature. 473: 174-80. PMID 21508958 DOI: 10.1038/Nature09944 |
0.474 |
|
| 2011 |
Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, Børglum AD, Werge T, Purcell S, ... ... Brunak S, et al. Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes. Genetic Epidemiology. 35: 318-32. PMID 21484861 DOI: 10.1002/Gepi.20580 |
0.377 |
|
| 2011 |
Wesolowska A, Dalgaard MD, Borst L, Gautier L, Bak M, Weinhold N, Nielsen BF, Helt LR, Audouze K, Nersting J, Tommerup N, Brunak S, Sicheritz-Ponten T, Leffers H, Schmiegelow K, et al. Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia. Leukemia. 25: 1001-6. PMID 21415851 DOI: 10.1038/Leu.2011.32 |
0.311 |
|
| 2011 |
Banasik K, Justesen JM, Hornbak M, Krarup NT, Gjesing AP, Sandholt CH, Jensen TS, Grarup N, Andersson A, Jørgensen T, Witte DR, Sandbæk A, Lauritzen T, Thorens B, Brunak S, et al. Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. Plos One. 6: e16542. PMID 21339799 DOI: 10.1371/Journal.Pone.0016542 |
0.332 |
|
| 2011 |
Taboureau O, Nielsen SK, Audouze K, Weinhold N, Edsgärd D, Roque FS, Kouskoumvekaki I, Bora A, Curpan R, Jensen TS, Brunak S, Oprea TI. ChemProt: a disease chemical biology database. Nucleic Acids Research. 39: D367-72. PMID 20935044 DOI: 10.1093/Nar/Gkq906 |
0.345 |
|
| 2010 |
Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, ... ... Brunak S, et al. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Molecular Systems Biology. 6: 381. PMID 20571530 DOI: 10.1038/Msb.2010.36 |
0.319 |
|
| 2010 |
Audouze K, Juncker AS, Roque FJ, Krysiak-Baltyn K, Weinhold N, Taboureau O, Jensen TS, Brunak S. Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks. Plos Computational Biology. 6: e1000788. PMID 20502671 DOI: 10.1371/Journal.Pcbi.1000788 |
0.327 |
|
| 2010 |
Blicher T, Gupta R, Wesolowska A, Jensen LJ, Brunak S. Protein annotation in the era of personal genomics. Current Opinion in Structural Biology. 20: 335-41. PMID 20403684 DOI: 10.1016/J.Sbi.2010.03.008 |
0.547 |
|
| 2010 |
Brorsson C, Tue Hansen N, Bergholdt R, Brunak S, Pociot F. The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes. Plos One. 5: e9576. PMID 20221424 DOI: 10.1371/Journal.Pone.0009576 |
0.33 |
|
| 2010 |
Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, Nielsen T, Pons N, Levenez F, Yamada T, Mende DR, Li J, Xu J, Li S, Li D, ... ... Brunak S, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 464: 59-65. PMID 20203603 DOI: 10.1038/Nature08821 |
0.492 |
|
| 2010 |
Rasmussen M, Li Y, Lindgreen S, Pedersen JS, Albrechtsen A, Moltke I, Metspalu M, Metspalu E, Kivisild T, Gupta R, Bertalan M, Nielsen K, Gilbert MT, Wang Y, Raghavan M, ... ... Brunak S, et al. Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature. 463: 757-62. PMID 20148029 DOI: 10.1038/Nature08835 |
0.315 |
|
| 2010 |
Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Science Signaling. 3: ra3. PMID 20068231 DOI: 10.1126/Scisignal.2000475 |
0.525 |
|
| 2010 |
Gauthier NP, Jensen LJ, Wernersson R, Brunak S, Jensen TS. Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results. Nucleic Acids Research. 38: D699-702. PMID 19934261 DOI: 10.1093/Nar/Gkp1044 |
0.543 |
|
| 2010 |
Wesolowska A, Dalgaard MD, Borst L, Gautier L, Bak M, Weinhold N, Nielsen BF, Nersting J, Tommerup N, Brunak S, Ponten TS, Leffers H, Schmiegelow K, Gupta R. Relating genomic variation to drug response in childhood acute lymphoblastic leukemia by multiplexed targeted sequencing Genome Biology. 11: 41. DOI: 10.1186/Gb-2010-11-S1-P41 |
0.324 |
|
| 2009 |
Juncker AS, Larsen MV, Weinhold N, Nielsen M, Brunak S, Lund O. Systematic characterisation of cellular localisation and expression profiles of proteins containing MHC ligands. Plos One. 4: e7448. PMID 19826487 DOI: 10.1371/Journal.Pone.0007448 |
0.3 |
|
| 2009 |
Bergholdt R, Brorsson C, Lage K, Nielsen JH, Brunak S, Pociot F. Expression profiling of human genetic and protein interaction networks in type 1 diabetes. Plos One. 4: e6250. PMID 19609442 DOI: 10.1371/Journal.Pone.0006250 |
0.348 |
|
| 2009 |
Hansen NT, Brunak S, Altman RB. Generating genome-scale candidate gene lists for pharmacogenomics. Clinical Pharmacology and Therapeutics. 86: 183-9. PMID 19369935 DOI: 10.1038/Clpt.2009.42 |
0.321 |
|
| 2009 |
Juncker AS, Jensen LJ, Pierleoni A, Bernsel A, Tress ML, Bork P, von Heijne G, Valencia A, Ouzounis CA, Casadio R, Brunak S. Sequence-based feature prediction and annotation of proteins. Genome Biology. 10: 206. PMID 19226438 DOI: 10.1186/Gb-2009-10-2-206 |
0.635 |
|
| 2009 |
Brorsson C, Hansen NT, Lage K, Bergholdt R, Brunak S, Pociot F. Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data. Diabetes, Obesity & Metabolism. 11: 60-6. PMID 19143816 DOI: 10.1111/J.1463-1326.2008.01004.X |
0.353 |
|
| 2009 |
Wang K, Ussery DW, Brunak S. Analysis and prediction of gene splice sites in four Aspergillus genomes. Fungal Genetics and Biology : Fg & B. 46: S14-8. PMID 18948220 DOI: 10.1016/J.Fgb.2008.09.010 |
0.362 |
|
| 2008 |
Miller ML, Jensen LJ, Diella F, Jørgensen C, Tinti M, Li L, Hsiung M, Parker SA, Bordeaux J, Sicheritz-Ponten T, Olhovsky M, Pasculescu A, Alexander J, Knapp S, Blom N, ... ... Brunak S, et al. Linear motif atlas for phosphorylation-dependent signaling. Science Signaling. 1: ra2. PMID 18765831 DOI: 10.1126/Scisignal.1159433 |
0.594 |
|
| 2008 |
Jensen LJ, de Lichtenberg U, Jensen TS, Brunak S, Bork P. Circular reasoning rather than cyclic expression. Genome Biology. 9: 403. PMID 18598377 DOI: 10.1186/Gb-2008-9-6-403 |
0.578 |
|
| 2008 |
Spicker JS, Brunak S, Frederiksen KS, Toft H. Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 444-54. PMID 18178960 DOI: 10.1093/Toxsci/Kfn001 |
0.3 |
|
| 2008 |
Gauthier NP, Larsen ME, Wernersson R, de Lichtenberg U, Jensen LJ, Brunak S, Jensen TS. Cyclebase.org--a comprehensive multi-organism online database of cell-cycle experiments. Nucleic Acids Research. 36: D854-9. PMID 17940094 DOI: 10.1093/Nar/Gkm729 |
0.535 |
|
| 2008 |
Lamberth K, Nielsen M, Lundegaard C, Worning P, Laurmøller SL, Lund O, Brunak S, Buus S. ‘Query-by Committee’- An Efficient Method to Select Information-Rich Data for the Development of Peptide-HLA-Binding Predictors Scandinavian Journal of Immunology. 59: 633-633. DOI: 10.1111/J.0300-9475.2004.01423Bf.X |
0.316 |
|
| 2008 |
Jensen LJ, Lichtenberg Ud, Jensen TS, Brunak S, Bork P. Just-in-time assembly of cell-cycle protein complexes Nature Precedings. DOI: 10.1038/Npre.2008.2273.1 |
0.446 |
|
| 2007 |
Bergholdt R, Størling ZM, Lage K, Karlberg EO, Olason PI, Aalund M, Nerup J, Brunak S, Workman CT, Pociot F. Integrative analysis for finding genes and networks involved in diabetes and other complex diseases. Genome Biology. 8: R253. PMID 18045462 DOI: 10.1186/Gb-2007-8-11-R253 |
0.336 |
|
| 2007 |
de Lichtenberg U, Jensen TS, Brunak S, Bork P, Jensen LJ. Evolution of cell cycle control: same molecular machines, different regulation. Cell Cycle (Georgetown, Tex.). 6: 1819-25. PMID 17671420 DOI: 10.4161/Cc.6.15.4537 |
0.612 |
|
| 2007 |
Spicker JS, Pedersen HT, Nielsen HB, Brunak S. Analysis of cell death inducing compounds. Archives of Toxicology. 81: 803-11. PMID 17503021 DOI: 10.1007/S00204-007-0207-4 |
0.317 |
|
| 2007 |
Emanuelsson O, Brunak S, von Heijne G, Nielsen H. Locating proteins in the cell using TargetP, SignalP and related tools. Nature Protocols. 2: 953-71. PMID 17446895 DOI: 10.1038/Nprot.2007.131 |
0.357 |
|
| 2007 |
Gorodkin J, Cirera S, Hedegaard J, Gilchrist MJ, Panitz F, Jørgensen C, Scheibye-Knudsen K, Arvin T, Lumholdt S, Sawera M, Green T, Nielsen BJ, Havgaard JH, Rosenkilde C, Wang J, ... ... Brunak S, et al. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Genome Biology. 8: R45. PMID 17407547 DOI: 10.1186/Gb-2007-8-4-R45 |
0.323 |
|
| 2007 |
Tress ML, Martelli PL, Frankish A, Reeves GA, Wesselink JJ, Yeats C, Olason PI, Albrecht M, Hegyi H, Giorgetti A, Raimondo D, Lagarde J, Laskowski RA, López G, Sadowski MI, ... ... Brunak S, et al. The implications of alternative splicing in the ENCODE protein complement. Proceedings of the National Academy of Sciences of the United States of America. 104: 5495-500. PMID 17372197 DOI: 10.1073/Pnas.0700800104 |
0.34 |
|
| 2007 |
Lage K, Karlberg EO, Størling ZM, Olason PI, Pedersen AG, Rigina O, Hinsby AM, Tümer Z, Pociot F, Tommerup N, Moreau Y, Brunak S. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nature Biotechnology. 25: 309-16. PMID 17344885 DOI: 10.1038/Nbt1295 |
0.345 |
|
| 2006 |
Rapin N, Kesmir C, Frankild S, Nielsen M, Lundegaard C, Brunak S, Lund O. Modelling the human immune system by combining bioinformatics and systems biology approaches. Journal of Biological Physics. 32: 335-53. PMID 19669470 DOI: 10.1007/S10867-006-9019-7 |
0.321 |
|
| 2006 |
Jensen LJ, Jensen TS, de Lichtenberg U, Brunak S, Bork P. Co-evolution of transcriptional and post-translational cell-cycle regulation. Nature. 443: 594-7. PMID 17006448 DOI: 10.1038/Nature05186 |
0.62 |
|
| 2006 |
Johansen MB, Kiemer L, Brunak S. Analysis and prediction of mammalian protein glycation. Glycobiology. 16: 844-53. PMID 16762979 DOI: 10.1093/Glycob/Cwl009 |
0.311 |
|
| 2006 |
Hinsby AM, Kiemer L, Karlberg EO, Lage K, Fausbøll A, Juncker AS, Andersen JS, Mann M, Brunak S. A wiring of the human nucleolus. Molecular Cell. 22: 285-95. PMID 16630896 DOI: 10.1016/J.Molcel.2006.03.012 |
0.356 |
|
| 2005 |
de Lichtenberg U, Wernersson R, Jensen TS, Nielsen HB, Fausbøll A, Schmidt P, Hansen FB, Knudsen S, Brunak S. New weakly expressed cell cycle-regulated genes in yeast. Yeast (Chichester, England). 22: 1191-201. PMID 16278933 DOI: 10.1002/Yea.1302 |
0.307 |
|
| 2005 |
Bendtsen JD, Kiemer L, Fausbøll A, Brunak S. Non-classical protein secretion in bacteria. Bmc Microbiology. 5: 58. PMID 16212653 DOI: 10.1186/1471-2180-5-58 |
0.346 |
|
| 2005 |
Wernersson R, Schierup MH, Jørgensen FG, Gorodkin J, Panitz F, Staerfeldt HH, Christensen OF, Mailund T, Hornshøj H, Klein A, Wang J, Liu B, Hu S, Dong W, Li W, ... ... Brunak S, et al. Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. Bmc Genomics. 6: 70. PMID 15885146 DOI: 10.1186/1471-2164-6-70 |
0.328 |
|
| 2005 |
de Lichtenberg U, Jensen LJ, Brunak S, Bork P. Dynamic complex formation during the yeast cell cycle. Science (New York, N.Y.). 307: 724-7. PMID 15692050 DOI: 10.1126/Science.1105103 |
0.611 |
|
| 2005 |
de Lichtenberg U, Jensen LJ, Fausbøll A, Jensen TS, Bork P, Brunak S. Comparison of computational methods for the identification of cell cycle-regulated genes. Bioinformatics (Oxford, England). 21: 1164-71. PMID 15513999 DOI: 10.1093/Bioinformatics/Bti093 |
0.612 |
|
| 2005 |
Julenius K, Mølgaard A, Gupta R, Brunak S. Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites Glycobiology. 15: 153-164. PMID 15385431 DOI: 10.1093/Glycob/Cwh151 |
0.332 |
|
| 2004 |
La Cour T, Kiemer L, Mølgaard A, Gupta R, Skriver K, Brunak S. Analysis and prediction of leucine-rich nuclear export signals Protein Engineering, Design and Selection. 17: 527-536. PMID 15314210 DOI: 10.1093/Protein/Gzh062 |
0.327 |
|
| 2004 |
Hjerrild M, Stensballe A, Rasmussen TE, Kofoed CB, Blom N, Sicheritz-Ponten T, Larsen MR, Brunak S, Jensen ON, Gammeltoft S. Identification of phosphorylation sites in protein kinase A substrates using artificial neural networks and mass spectrometry. Journal of Proteome Research. 3: 426-33. PMID 15253423 DOI: 10.1021/Pr0341033 |
0.302 |
|
| 2004 |
Bendtsen JD, Nielsen H, von Heijne G, Brunak S. Improved prediction of signal peptides: SignalP 3.0. Journal of Molecular Biology. 340: 783-95. PMID 15223320 DOI: 10.1016/J.Jmb.2004.05.028 |
0.307 |
|
| 2004 |
Kiemer L, Lund O, Brunak S, Blom N. Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology Bmc Bioinformatics. 5. PMID 15180906 DOI: 10.1186/1471-2105-5-72 |
0.354 |
|
| 2004 |
Blom N, Sicheritz-Pontén T, Gupta R, Gammeltoft S, Brunak S. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics. 4: 1633-49. PMID 15174133 DOI: 10.1002/Pmic.200300771 |
0.343 |
|
| 2004 |
Bendtsen JD, Jensen LJ, Blom N, Von Heijne G, Brunak S. Feature-based prediction of non-classical and leaderless protein secretion. Protein Engineering, Design & Selection : Peds. 17: 349-56. PMID 15115854 DOI: 10.1093/Protein/Gzh037 |
0.547 |
|
| 2004 |
Duckert P, Brunak S, Blom N. Prediction of proprotein convertase cleavage sites Protein Engineering, Design and Selection. 17: 107-112. PMID 14985543 DOI: 10.1093/Protein/Gzh013 |
0.322 |
|
| 2004 |
Eden E, Brunak S. Analysis and recognition of 5′ UTR intron splice sites in human pre-mRNA Nucleic Acids Research. 32: 1131-1142. PMID 14960723 DOI: 10.1093/Nar/Gkh273 |
0.306 |
|
| 2004 |
Andersen CAF, Brunak S. Representation of Protein-Sequence Information by Amino Acid Subalphabets Ai Magazine. 25: 97-104. DOI: 10.1609/Aimag.V25I1.1750 |
0.348 |
|
| 2003 |
Jensen LJ, Ussery DW, Brunak S. Functionality of system components: conservation of protein function in protein feature space. Genome Research. 13: 2444-9. PMID 14559779 DOI: 10.1101/Gr.1190803 |
0.551 |
|
| 2003 |
Juncker AS, Willenbrock H, Von Heijne G, Brunak S, Nielsen H, Krogh A. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Protein Science : a Publication of the Protein Society. 12: 1652-62. PMID 12876315 DOI: 10.1110/Ps.0303703 |
0.336 |
|
| 2003 |
Saxová P, Buus S, Brunak S, Keşmir C. Predicting proteasomal cleavage sites: A comparison of available methods International Immunology. 15: 781-787. PMID 12807816 DOI: 10.1093/Intimm/Dxg084 |
0.308 |
|
| 2003 |
de Lichtenberg U, Jensen TS, Jensen LJ, Brunak S. Protein feature based identification of cell cycle regulated proteins in yeast. Journal of Molecular Biology. 329: 663-74. PMID 12787668 DOI: 10.1016/S0022-2836(03)00490-X |
0.553 |
|
| 2003 |
Nielsen M, Lundegaard C, Worning P, Lauemøller SL, Lamberth K, Buus S, Brunak S, Lund O. Reliable prediction of T-cell epitopes using neural networks with novel sequence representations Protein Science. 12: 1007-1017. PMID 12717023 DOI: 10.1110/Ps.0239403 |
0.315 |
|
| 2003 |
Jensen LJ, Gupta R, Staerfeldt HH, Brunak S. Prediction of human protein function according to Gene Ontology categories. Bioinformatics (Oxford, England). 19: 635-42. PMID 12651722 DOI: 10.1093/Bioinformatics/Btg036 |
0.576 |
|
| 2002 |
Jensen LJ, Skovgaard M, Brunak S. Prediction of novel archaeal enzymes from sequence-derived features. Protein Science : a Publication of the Protein Society. 11: 2894-8. PMID 12441387 DOI: 10.1110/Ps.0225102 |
0.543 |
|
| 2002 |
Workman C, Jensen LJ, Jarmer H, Berka R, Gautier L, Nielser HB, Saxild HH, Nielsen C, Brunak S, Knudsen S. A new non-linear normalization method for reducing variability in DNA microarray experiments. Genome Biology. 3: research0048. PMID 12225587 DOI: 10.1186/Gb-2002-3-9-Research0048 |
0.503 |
|
| 2002 |
Jensen LJ, Gupta R, Blom N, Devos D, Tamames J, Kesmir C, Nielsen H, Staerfeldt HH, Rapacki K, Workman C, Andersen CA, Knudsen S, Krogh A, Valencia A, Brunak S. Prediction of human protein function from post-translational modifications and localization features. Journal of Molecular Biology. 319: 1257-65. PMID 12079362 DOI: 10.1016/S0022-2836(02)00379-0 |
0.549 |
|
| 2002 |
Gupta R, Jensen LJ, Brunak S. Orphan protein function and its relation to glycosylation. Ernst Schering Research Foundation Workshop. 276-94. PMID 12061006 |
0.442 |
|
| 2002 |
Skovgaard M, Jensen LJ, Friis C, Stærfeldt HH, Worning P, Brunak S, Ussery D. The Atlas visualization of genomewide information Methods in Microbiology. 33: 49-63. DOI: 10.1016/S0580-9517(02)33004-6 |
0.503 |
|
| 2001 |
Skovgaard M, Jensen LJ, Brunak S, Ussery D, Krogh A. On the total number of genes and their length distribution in complete microbial genomes. Trends in Genetics : Tig. 17: 425-8. PMID 11485798 DOI: 10.1016/S0168-9525(01)02372-1 |
0.542 |
|
| 2001 |
Ussery D, Larsen TS, Wilkes KT, Friis C, Worning P, Krogh A, Brunak S. Genome organisation and chromatin structure in Escherichia coli. Biochimie. 83: 201-12. PMID 11278070 DOI: 10.1016/S0300-9084(00)01225-6 |
0.315 |
|
| 2000 |
Petersen TN, Lundegaard C, Nielsen M, Bohr H, Bohr J, Brunak S, Gippert GP, Lund O. Prediction of protein secondary structure at 80% accuracy Proteins: Structure, Function and Genetics. 41: 17-20. PMID 10944389 DOI: 10.1002/1097-0134(20001001)41:1<17::Aid-Prot40>3.0.Co;2-F |
0.307 |
|
| 2000 |
Emanuelsson O, Nielsen H, Brunak S, Von Heijne G. Predicting subcellular localization of proteins based on their N-terminal amino acid sequence Journal of Molecular Biology. 300: 1005-1016. PMID 10891285 DOI: 10.1006/Jmbi.2000.3903 |
0.342 |
|
| 2000 |
Pedersen AG, Jensen LJ, Brunak S, Staerfeldt HH, Ussery DW. A DNA structural atlas for Escherichia coli. Journal of Molecular Biology. 299: 907-30. PMID 10843847 DOI: 10.1006/Jmbi.2000.3787 |
0.518 |
|
| 2000 |
Worning P, Jensen LJ, Nelson KE, Brunak S, Ussery DW. Structural analysis of DNA sequence: evidence for lateral gene transfer in Thermotoga maritima. Nucleic Acids Research. 28: 706-9. PMID 10637321 DOI: 10.1093/Nar/28.3.706 |
0.538 |
|
| 1999 |
Blom N, Gammeltoft S, Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites Journal of Molecular Biology. 294: 1351-1362. PMID 10600390 DOI: 10.1006/Jmbi.1999.3310 |
0.327 |
|
| 1999 |
Gupta R, Jung E, Gooley AA, Williams KL, Brunak S, Hansen J. Scanning the available Dictyostelium discoideum proteome for O-linked GlcNAc glycosylation sites using neural networks Glycobiology. 9: 1009-1022. PMID 10521537 DOI: 10.1093/Glycob/9.10.1009 |
0.325 |
|
| 1999 |
Pedersen AG, Baldi P, Chauvin Y, Brunak S. The biology of eukaryotic promoter prediction - A review Computers and Chemistry. 23: 191-207. PMID 10404615 DOI: 10.1016/S0097-8485(99)00015-7 |
0.306 |
|
| 1999 |
Nielsen H, Brunak S, Von Heijne G. Machine learning approaches for the prediction of signal peptides and other protein sorting signals Protein Engineering. 12: 3-9. PMID 10065704 DOI: 10.1093/Protein/12.1.3 |
0.316 |
|
| 1999 |
Kreegipuu A, Blom N, Brunak S. PhosphoBase, a database of phosphorylation sites: Release 2.0 Nucleic Acids Research. 27: 237-239. PMID 9847189 DOI: 10.1093/Nar/27.1.237 |
0.301 |
|
| 1998 |
Østergaard L, Pedersen AG, Jespersen HM, Brunak S, Welinder KG. Computational analyses and annotations of the Arabidopsis peroxidase gene family Febs Letters. 433: 98-102. PMID 9738941 DOI: 10.1016/S0014-5793(98)00849-7 |
0.329 |
|
| 1998 |
Kreegipuu A, Blom N, Brunak S, Järv J. Statistical analysis of protein kinase specificity determinants Febs Letters. 430: 45-50. PMID 9678592 DOI: 10.1016/S0014-5793(98)00503-1 |
0.32 |
|
| 1998 |
Blom N, Kreegipuu A, Brunak S. PhosphoBase: A database of phosphorylation sites Nucleic Acids Research. 26: 382-386. PMID 9399879 DOI: 10.1093/Nar/26.1.382 |
0.311 |
|
| 1997 |
Nielsen H, Engelbrecht J, Brunak S, von Heijne G. A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites International Journal of Neural Systems. 8: 581-599. PMID 10065837 DOI: 10.1142/S0129065797000537 |
0.318 |
|
| 1997 |
Lund O, Frimand K, Gorodkin J, Bohr H, Bohr J, Hansen J, Brunak S. Protein distance constraints predicted by neural networks and probability density functions Protein Engineering. 10: 1241-1248. PMID 9514112 DOI: 10.1093/Protein/10.11.1241 |
0.322 |
|
| 1997 |
Claros MG, Brunak S, Heijne GV. Prediction of N-terminal protein sorting signals Current Opinion in Structural Biology. 7: 394-398. PMID 9204282 DOI: 10.1016/S0959-440X(97)80057-7 |
0.321 |
|
| 1997 |
Nielsen H, Engelbrecht J, Brunak S, von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Engineering. 10: 1-6. PMID 9051728 DOI: 10.1093/Protein/10.1.1 |
0.316 |
|
| 1997 |
Blom N, Hansen J, Blaas D, Brunak S. Cleavage site analysis in picornaviral polyproteins: discovering cellular targets by neural networks. Protein Science : a Publication of the Protein Society. 5: 2203-16. PMID 8931139 DOI: 10.1002/Pro.5560051107 |
0.327 |
|
| 1997 |
Bohr H, Brunak S. Distance-based approaches to protein structure determination III (Copenhagen, Denmark, 5-8 November 1996) - Introductory overview Folding and Design. 2: S1-S2. DOI: 10.1016/S1359-0278(97)00054-0 |
0.32 |
|
| 1996 |
Baldi P, Brunak S, Chauvin Y, Krogh A. Naturally occurring nucleosome positioning signals in human exons and introns Journal of Molecular Biology. 263: 503-510. PMID 8918932 DOI: 10.1006/Jmbi.1996.0592 |
0.323 |
|
| 1996 |
Nielsen H, Engelbrecht J, von Heijne G, Brunak S. Defining a similarity threshold for a functional protein sequence pattern: the signal peptide cleavage site. Proteins. 24: 165-77. PMID 8820484 DOI: 10.1002/(Sici)1097-0134(199602)24:2<165::Aid-Prot4>3.0.Co;2-I |
0.332 |
|
| 1996 |
Brunak S, Engelbrecht J. Protein structure and the sequential structure of mRNA: alpha-helix and beta-sheet signals at the nucleotide level. Proteins. 25: 237-52. PMID 8811739 DOI: 10.1002/(Sici)1097-0134(199606)25:2<237::Aid-Prot9>3.0.Co;2-E |
0.318 |
|
| 1996 |
Hebsgaard SM, Korning PG, Tolstrup N, Engelbrecht J, Rouzé P, Brunak S. Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information. Nucleic Acids Research. 24: 3439-52. PMID 8811101 DOI: 10.1093/Nar/24.17.3439 |
0.322 |
|
| 1995 |
Larsen NI, Engelbrecht J, Brunak S. Analysis of eukaryotic promoter sequences reveals a systematically occurring CT-signal. Nucleic Acids Research. 23: 1223-30. PMID 7739901 DOI: 10.1093/Nar/23.7.1223 |
0.302 |
|
| 1993 |
Bohr J, Bohr H, Brunak S, Cotterill RM, Fredholm H, Lautrup B, Petersen SB. Protein structures from distance inequalities. Journal of Molecular Biology. 231: 861-9. PMID 7685827 DOI: 10.1006/Jmbi.1993.1332 |
0.3 |
|
| 1992 |
Engelbrecht J, Knudsen S, Brunak S. G+C-rich tract in 5' end of human introns. Journal of Molecular Biology. 227: 108-13. PMID 1522582 DOI: 10.1016/0022-2836(92)90685-D |
0.31 |
|
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