Richard R. Copley - Publications

Affiliations: 
Wellcome Trust Centre for Human Genetics Nuffield Department of Clinical Medicine, Oxford, England, United Kingdom 
Website:
http://www.ndm.ox.ac.uk/researcher/richard-copley

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Marlétaz F, Couloux A, Poulain J, Labadie K, Da Silva C, Mangenot S, Noel B, Poustka AJ, Dru P, Pegueroles C, Borra M, Lowe EK, Lhomond G, Besnardeau L, Le Gras S, ... ... Copley RR, et al. Analysis of the sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes. Cell Genomics. 3: 100295. PMID 37082140 DOI: 10.1016/j.xgen.2023.100295  0.333
2016 Camps C, Petousi N, Bento C, Cario H, Copley RR, McMullin MF, vanWijk R, Ratcliffe PJ, Robbins PA, Taylor JC. Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations. Haematologica. PMID 27651169 DOI: 10.3324/Haematol.2016.144063  0.419
2015 Taylor JC, Martin HC, Lise S, Broxholme J, Cazier JB, Rimmer A, Kanapin A, Lunter G, Fiddy S, Allan C, Aricescu AR, Attar M, Babbs C, Becq J, Beeson D, ... ... Copley RR, et al. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nature Genetics. 47: 717-26. PMID 25985138 DOI: 10.1038/Ng.3304  0.321
2014 Martin HC, Kim GE, Pagnamenta AT, Murakami Y, Carvill GL, Meyer E, Copley RR, Rimmer A, Barcia G, Fleming MR, Kronengold J, Brown MR, Hudspith KA, Broxholme J, Kanapin A, et al. Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis. Human Molecular Genetics. 23: 3200-11. PMID 24463883 DOI: 10.1093/Hmg/Ddu030  0.334
2013 Hosseini M, Goodstadt L, Hughes JR, Kowalczyk MS, de Gobbi M, Otto GW, Copley RR, Mott R, Higgs DR, Flint J. Causes and consequences of chromatin variation between inbred mice. Plos Genetics. 9: e1003570. PMID 23785304 DOI: 10.1371/Journal.Pgen.1003570  0.33
2013 Li YI, Copley RR. Scaffolding low quality genomes using orthologous protein sequences. Bioinformatics (Oxford, England). 29: 160-5. PMID 23162087 DOI: 10.1093/Bioinformatics/Bts661  0.525
2013 Shanks ME, Downes SM, Copley RR, Lise S, Broxholme J, Hudspith KA, Kwasniewska A, Davies WI, Hankins MW, Packham ER, Clouston P, Seller A, Wilkie AO, Taylor JC, Ragoussis J, et al. Next-generation sequencing (NGS) as a diagnostic tool for retinal degeneration reveals a much higher detection rate in early-onset disease. European Journal of Human Genetics : Ejhg. 21: 274-80. PMID 22968130 DOI: 10.1038/Ejhg.2012.172  0.341
2012 Davies WI, Downes SM, Fu JK, Shanks ME, Copley RR, Lise S, Ramsden SC, Black GC, Gibson K, Foster RG, Hankins MW, Németh AH. Next-generation sequencing in health-care delivery: lessons from the functional analysis of rhodopsin. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 891-9. PMID 22791210 DOI: 10.1038/Gim.2012.73  0.383
2011 Telford MJ, Copley RR. Improving animal phylogenies with genomic data. Trends in Genetics : Tig. 27: 186-95. PMID 21414681 DOI: 10.1016/J.Tig.2011.02.003  0.484
2009 Taylor JM, Street TL, Hao L, Copley R, Taylor MS, Hayden PJ, Stolper G, Mott R, Hein J, Moffatt MF, Cookson WO. Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes. Plos One. 4: e7651. PMID 19888454 DOI: 10.1371/Journal.Pone.0007651  0.32
2008 Juliusdottir T, Pettersson F, Copley RR. POPE--a tool to aid high-throughput phylogenetic analysis. Bioinformatics (Oxford, England). 24: 2778-9. PMID 18849569 DOI: 10.1093/Bioinformatics/Btn533  0.327
2008 Copley RR. The animal in the genome: comparative genomics and evolution. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 1453-61. PMID 18192189 DOI: 10.1098/Rstb.2007.2235  0.486
2008 Fullerton JM, Willis-Owen SA, Yalcin B, Shifman S, Copley RR, Miller SR, Bhomra A, Davidson S, Oliver PL, Mott R, Flint J. Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus. Biological Psychiatry. 63: 874-83. PMID 18083140 DOI: 10.1016/J.Biopsych.2007.10.019  0.403
2008 Taylor MS, Copley RR. Comparative Genomics Bioinformatics-From Genomes to Therapies. 3: 1335-1374. DOI: 10.1002/9783527619368.ch37  0.311
2007 Copley RR, Totrov M, Linnell J, Field S, Ragoussis J, Udalova IA. Functional conservation of Rel binding sites in drosophilid genomes. Genome Research. 17: 1327-35. PMID 17785540 DOI: 10.1101/Gr.6490707  0.454
2007 Hull J, Campino S, Rowlands K, Chan MS, Copley RR, Taylor MS, Rockett K, Elvidge G, Keating B, Knight J, Kwiatkowski D. Identification of common genetic variation that modulates alternative splicing. Plos Genetics. 3: e99. PMID 17571926 DOI: 10.1371/Journal.Pgen.0030099  0.329
2007 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Bork P, Buillard V, Cerutti L, Copley R, Courcelle E, Das U, Daugherty L, Dibley M, Finn R, et al. New developments in the InterPro database. Nucleic Acids Research. 35: D224-8. PMID 17202162 DOI: 10.1093/Nar/Gkl841  0.744
2006 Webster BL, Copley RR, Jenner RA, Mackenzie-Dodds JA, Bourlat SJ, Rota-Stabelli O, Littlewood DT, Telford MJ. Mitogenomics and phylogenomics reveal priapulid worms as extant models of the ancestral Ecdysozoan. Evolution & Development. 8: 502-10. PMID 17073934 DOI: 10.1111/J.1525-142X.2006.00123.X  0.407
2006 Bourlat SJ, Juliusdottir T, Lowe CJ, Freeman R, Aronowicz J, Kirschner M, Lander ES, Thorndyke M, Nakano H, Kohn AB, Heyland A, Moroz LL, Copley RR, Telford MJ. Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida. Nature. 444: 85-8. PMID 17051155 DOI: 10.1038/Nature05241  0.371
2006 Matus DQ, Copley RR, Dunn CW, Hejnol A, Eccleston H, Halanych KM, Martindale MQ, Telford MJ. Broad taxon and gene sampling indicate that chaetognaths are protostomes. Current Biology : Cb. 16: R575-6. PMID 16890509 DOI: 10.1016/J.Cub.2006.07.017  0.322
2006 Letunic I, Copley RR, Pils B, Pinkert S, Schultz J, Bork P. SMART 5: domains in the context of genomes and networks. Nucleic Acids Research. 34: D257-60. PMID 16381859 DOI: 10.1093/Nar/Gkj079  0.784
2005 Copley RR. The EH1 motif in metazoan transcription factors. Bmc Genomics. 6: 169. PMID 16309560 DOI: 10.1186/1471-2164-6-169  0.488
2005 Brown JH, Bihoreau MT, Hoffmann S, Kränzlin B, Tychinskaya I, Obermüller N, Podlich D, Boehn SN, Kaisaki PJ, Megel N, Danoy P, Copley RR, Broxholme J, Witzgall R, Lathrop M, et al. Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat. Journal of the American Society of Nephrology : Jasn. 16: 3517-26. PMID 16207829 DOI: 10.1681/Asn.2005060601  0.33
2005 Pils B, Copley RR, Schultz J. Variation in structural location and amino acid conservation of functional sites in protein domain families. Bmc Bioinformatics. 6: 210. PMID 16122386 DOI: 10.1186/1471-2105-6-210  0.426
2005 Vinuesa CG, Cook MC, Angelucci C, Athanasopoulos V, Rui L, Hill KM, Yu D, Domaschenz H, Whittle B, Lambe T, Roberts IS, Copley RR, Bell JI, Cornall RJ, Goodnow CC. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature. 435: 452-8. PMID 15917799 DOI: 10.1038/Nature03555  0.361
2005 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Bradley P, Bork P, Bucher P, Cerutti L, Copley R, Courcelle E, Das U, Durbin R, Fleischmann W, et al. InterPro, progress and status in 2005. Nucleic Acids Research. 33: D201-5. PMID 15608177 DOI: 10.1093/Nar/Gki106  0.765
2004 Velayos-Baeza A, Vettori A, Copley RR, Dobson-Stone C, Monaco AP. Analysis of the human VPS13 gene family. Genomics. 84: 536-49. PMID 15498460 DOI: 10.1016/J.Ygeno.2004.04.012  0.399
2004 Yalcin B, Fullerton J, Miller S, Keays DA, Brady S, Bhomra A, Jefferson A, Volpi E, Copley RR, Flint J, Mott R. Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 9734-9. PMID 15210992 DOI: 10.1073/Pnas.0401189101  0.305
2004 Copley RR. Evolutionary convergence of alternative splicing in ion channels. Trends in Genetics : Tig. 20: 171-6. PMID 15101391 DOI: 10.1016/J.Tig.2004.02.001  0.383
2004 Copley RR, Aloy P, Russell RB, Telford MJ. Systematic searches for molecular synapomorphies in model metazoan genomes give some support for Ecdysozoa after accounting for the idiosyncrasies of Caenorhabditis elegans. Evolution & Development. 6: 164-9. PMID 15099303 DOI: 10.1111/J.1525-142X.2004.04021.X  0.486
2004 Taylor MS, Ponting CP, Copley RR. Occurrence and consequences of coding sequence insertions and deletions in Mammalian genomes. Genome Research. 14: 555-66. PMID 15059996 DOI: 10.1101/Gr.1977804  0.508
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Copley RR, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/Nature02426  0.809
2004 Letunic I, Copley RR, Schmidt S, Ciccarelli FD, Doerks T, Schultz J, Ponting CP, Bork P. SMART 4.0: towards genomic data integration. Nucleic Acids Research. 32: D142-4. PMID 14681379 DOI: 10.1093/Nar/Gkh088  0.817
2003 Copley RR, Goodstadt L, Ponting C. Eukaryotic domain evolution inferred from genome comparisons. Current Opinion in Genetics & Development. 13: 623-8. PMID 14638325 DOI: 10.1016/J.Gde.2003.10.004  0.549
2003 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Barrell D, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley RR, Courcelle E, Das U, Durbin R, et al. The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Research. 31: 315-8. PMID 12520011 DOI: 10.1093/Nar/Gkg046  0.797
2003 Copley RR, Russell RB. Getting the most from your protein sequence. Methods in Molecular Biology (Clifton, N.J.). 211: 411-30. PMID 12489448 DOI: 10.1385/1-59259-342-9:411  0.465
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Copley RR, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262  0.816
2002 Copley RR, Ponting CP, Schultz J, Bork P. Sequence analysis of multidomain proteins: past perspectives and future directions. Advances in Protein Chemistry. 61: 75-98. PMID 12461821 DOI: 10.1016/S0065-3233(02)61002-2  0.597
2002 Zdobnov EM, von Mering C, Letunic I, Torrents D, Suyama M, Copley RR, Christophides GK, Thomasova D, Holt RA, Subramanian GM, Mueller HM, Dimopoulos G, Law JH, Wells MA, Birney E, et al. Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Science (New York, N.Y.). 298: 149-59. PMID 12364792 DOI: 10.1126/Science.1077061  0.79
2002 Mulder NJ, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Biswas M, Bradley P, Bork P, Bucher P, Copley R, Courcelle E, Durbin R, Falquet L, Fleischmann W, et al. InterPro: an integrated documentation resource for protein families, domains and functional sites. Briefings in Bioinformatics. 3: 225-35. PMID 12230031 DOI: 10.1093/Bib/3.3.225  0.793
2002 Thomasova D, Ton LQ, Copley RR, Zdobnov EM, Wang X, Hong YS, Sim C, Bork P, Kafatos FC, Collins FH. Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae. Proceedings of the National Academy of Sciences of the United States of America. 99: 8179-84. PMID 12060762 DOI: 10.1073/Pnas.082235599  0.721
2002 Letunic I, Copley RR, Bork P. Common exon duplication in animals and its role in alternative splicing. Human Molecular Genetics. 11: 1561-7. PMID 12045209 DOI: 10.1093/Hmg/11.13.1561  0.764
2002 Copley RR, Doerks T, Letunic I, Bork P. Protein domain analysis in the era of complete genomes. Febs Letters. 513: 129-34. PMID 11911892 DOI: 10.1016/S0014-5793(01)03289-6  0.84
2002 Ciccarelli FD, Copley RR, Doerks T, Russell RB, Bork P. CASH--a beta-helix domain widespread among carbohydrate-binding proteins. Trends in Biochemical Sciences. 27: 59-62. PMID 11852237 DOI: 10.1016/S0968-0004(01)02046-1  0.786
2002 Copley RR, Letunic I, Bork P. Genome and protein evolution in eukaryotes. Current Opinion in Chemical Biology. 6: 39-45. PMID 11827821 DOI: 10.1016/S1367-5931(01)00278-2  0.792
2002 Gavin AC, Bösche M, Krause R, Grandi P, Marzioch M, Bauer A, Schultz J, Rick JM, Michon AM, Cruciat CM, Remor M, Höfert C, Schelder M, Brajenovic M, Ruffner H, ... ... Copley RR, et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 415: 141-7. PMID 11805826 DOI: 10.1038/415141A  0.539
2002 Doerks T, Copley RR, Schultz J, Ponting CP, Bork P. Systematic identification of novel protein domain families associated with nuclear functions. Genome Research. 12: 47-56. PMID 11779830 DOI: 10.1101/Gr.203201  0.771
2002 Letunic I, Goodstadt L, Dickens NJ, Doerks T, Schultz J, Mott R, Ciccarelli F, Copley RR, Ponting CP, Bork P. Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acids Research. 30: 242-4. PMID 11752305 DOI: 10.1093/Nar/30.1.242  0.802
2002 Holland PW, Copley RR, Snell EA, Furlong RF, Agapow P. Exploiting genomics in evolutionary developmental biology International Congress Series. 1246: 217-229. DOI: 10.1016/S0531-5131(02)01134-2  0.33
2001 Ponting CP, Mott R, Bork P, Copley RR. Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Genome Research. 11: 1996-2008. PMID 11731489 DOI: 10.1101/Gr.198701  0.66
2001 Copley RR, Russell RB, Ponting CP. Sialidase-like Asp-boxes: sequence-similar structures within different protein folds. Protein Science : a Publication of the Protein Society. 10: 285-92. PMID 11266614 DOI: 10.1110/Ps.31901  0.533
2001 Doerks T, Copley R, Bork P. DDT -- a novel domain in different transcription and chromosome remodeling factors. Trends in Biochemical Sciences. 26: 145-6. PMID 11246006 DOI: 10.1016/S0968-0004(00)01769-2  0.753
2001 Bork P, Copley R. Genome speak. Nature. 409: 815. PMID 11241984 DOI: 10.1038/35057269  0.493
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Copley RR, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.764
2001 Bork P, Copley R. The draft sequences. Filling in the gaps. Nature. 409: 818-20. PMID 11236994 DOI: 10.1038/35057274  0.585
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, Fitzhugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Copley RR, et al. Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) Nature. 412: 565-566. DOI: 10.1038/35087627  0.604
2000 Gönczy P, Echeverri C, Oegema K, Coulson A, Jones SJ, Copley RR, Duperon J, Oegema J, Brehm M, Cassin E, Hannak E, Kirkham M, Pichler S, Flohrs K, Goessen A, et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature. 408: 331-6. PMID 11099034 DOI: 10.1038/35042526  0.572
2000 Copley RR, Bork P. Homology among (betaalpha)(8) barrels: implications for the evolution of metabolic pathways. Journal of Molecular Biology. 303: 627-41. PMID 11054297 DOI: 10.1006/Jmbi.2000.4152  0.528
2000 Schultz J, Doerks T, Ponting CP, Copley RR, Bork P. More than 1,000 putative new human signalling proteins revealed by EST data mining. Nature Genetics. 25: 201-4. PMID 10835637 DOI: 10.1038/76069  0.796
2000 Ponting CP, Schultz J, Copley RR, Andrade MA, Bork P. Evolution of domain families. Advances in Protein Chemistry. 54: 185-244. PMID 10829229 DOI: 10.1016/S0065-3233(00)54007-8  0.538
2000 Schultz J, Copley RR, Doerks T, Ponting CP, Bork P. SMART: a web-based tool for the study of genetically mobile domains. Nucleic Acids Research. 28: 231-4. PMID 10592234 DOI: 10.1093/Nar/28.1.231  0.77
2000 Copley R. A broad look at bioinformatics Trends in Genetics. 16: 324. DOI: 10.1016/S0168-9525(00)01993-4  0.404
1999 Copley RR, Ponting CP, Bork P. Phospholipases A2 and Wnts are unlikely to share a common ancestor. Current Biology : Cb. 9: R718-9. PMID 10712041 DOI: 10.1016/S0960-9822(99)80466-7  0.392
1999 Barnes MR, Russell RB, Copley RR, Ponting CP, Bork P, Cumberledge S, Reichsman F, Moore HM. A lipid-binding domain in Wnt: a case of mistaken identity? Current Biology : Cb. 9: R717-9. PMID 10531014 DOI: 10.1016/S0960-9822(99)80465-5  0.561
1999 Koretke KK, Russell RB, Copley RR, Lupas AN. Fold recognition using sequence and secondary structure information. Proteins. 141-8. PMID 10526363 DOI: 10.1002/(Sici)1097-0134(1999)37:3+<141::Aid-Prot19>3.0.Co;2-F  0.426
1999 Copley RR, Schultz J, Ponting CP, Bork P. Protein families in multicellular organisms. Current Opinion in Structural Biology. 9: 408-15. PMID 10361098 DOI: 10.1016/S0959-440X(99)80055-4  0.638
1996 Russell RB, Copley RR, Barton GJ. Protein fold recognition by mapping predicted secondary structures. Journal of Molecular Biology. 259: 349-65. PMID 8676374 DOI: 10.1006/Jmbi.1996.0325  0.392
Show low-probability matches.