William T. Hu - Related publications

Affiliations: 
Neurology Emory University, Atlanta, GA 
Area:
Frontotemporal dementia, Alzheimer's disease, biomarkers
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 d'Abramo C, D'Adamio L, Giliberto L. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Sensitivity, Specificity and Potential for Clinical Use. Journal of Personalized Medicine. 10. PMID 32911755 DOI: 10.3390/jpm10030116   
2020 Knopman DS, Lundt ES, Therneau TM, Albertson SM, Gunter JL, Senjem ML, Schwarz CG, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Vemuri P, Kantarci K, Lowe VJ, ... , et al. Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment. Jama Neurology. PMID 33074304 DOI: 10.1001/jamaneurol.2020.3921   
2020 Narayanan SE, Sekhar N, Rajamma RG, Marathakam A, Al Mamun A, Uddin MS, Mathew B. Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease. Current Protein & Peptide Science. PMID 32957903 DOI: 10.2174/1389203721666200921152246   
2020 Low CYB, Lee JH, Lim FTW, Lee C, Ballard C, Francis PT, Lai MKP, Tan MGK. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias. Brain Pathology (Zurich, Switzerland). e12917. PMID 33128789 DOI: 10.1111/bpa.12917   
2020 Dutt S, Li Y, Mather M, Nation DA, . Brainstem Volumetric Integrity in Preclinical and Prodromal Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32925030 DOI: 10.3233/JAD-200187   
2020 Albrecht D, Isenberg AL, Stradford J, Monreal T, Sagare A, Pachicano M, Sweeney M, Toga A, Zlokovic B, Chui H, Joe E, Schneider L, Conti P, Jann K, Pa J, , et al. Associations between vascular function and tau PET are associated with global cognition and amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33046556 DOI: 10.1523/JNEUROSCI.1230-20.2020   
2020 Rubinski A, Franzmeier N, Neitzel J, Ewers M, . FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels. Alzheimer's Research & Therapy. 12: 133. PMID 33076977 DOI: 10.1186/s13195-020-00702-6   
2020 Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32962164 DOI: 10.3390/ijms21186867   
2020 Bartels C, Kögel A, Schweda M, Wiltfang J, Pentzek M, Schicktanz S, Schneider A. Use of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Risk in Mild Cognitive Impairment and Subjective Cognitive Decline in Routine Clinical Care in Germany. Journal of Alzheimer's Disease : Jad. PMID 33104034 DOI: 10.3233/JAD-200794   
2020 Zhu F, Li C, Chu F, Tian X, Zhu J. Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease. Frontiers in Aging Neuroscience. 12: 544235. PMID 33132894 DOI: 10.3389/fnagi.2020.544235   
2020 Ravona-Springer R, Sharvit-Ginon I, Ganmore I, Greenbaum L, Bendlin BB, Sternberg SA, Livny A, Domachevsky L, Sandler I, Ben Haim S, Golan S, Ben-Ami L, Lesman-Segev O, Manzali S, Heymann A, et al. The Israel Registry for Alzheimer's Prevention (IRAP) Study: Design and Baseline Characteristics. Journal of Alzheimer's Disease : Jad. PMID 33044181 DOI: 10.3233/JAD-200623   
2020 Wang L, Bharti, Kumar R, Pavlov PF, Winblad B. Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance. European Journal of Medicinal Chemistry. 112915. PMID 33139110 DOI: 10.1016/j.ejmech.2020.112915   
2020 Jack CR, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Whitwell J, et al. Predicting future rates of tau accumulation on PET. Brain : a Journal of Neurology. PMID 33094327 DOI: 10.1093/brain/awaa248   
2020 Rafii MS, Ances BM, Schupf N, Krinsky-McHale SJ, Mapstone M, Silverman W, Lott I, Klunk W, Head E, Christian B, Lai F, Rosas HD, Zaman S, Petersen ME, Strydom A, et al. The AT(N) framework for Alzheimer's disease in adults with Down syndrome. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12062. PMID 33134477 DOI: 10.1002/dad2.12062   
2020 Li S, Wang C, Wang W, Tan J. Trait anxiety, a personality risk factor associated with Alzheimer's Disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110124. PMID 33035604 DOI: 10.1016/j.pnpbp.2020.110124   
2020 O'Connor A, Weston PSJ, Pavisic IM, Ryan NS, Collins JD, Lu K, Crutch SJ, Alexander DC, Fox NC, Oxtoby NP. Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer's disease: a retrospective cohort analysis. Alzheimer's Research & Therapy. 12: 126. PMID 33023653 DOI: 10.1186/s13195-020-00695-2   
2020 Therriault J, Pascoal TA, Savard M, Benedet AL, Chamoun M, Tissot C, Lussier F, Kang MS, Thomas E, Terada T, Rej S, Massarweh G, Nasreddine Z, Vitali P, Soucy JP, et al. Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients. Neurology. PMID 33093220 DOI: 10.1212/WNL.0000000000011081   
2020 Malarte ML, Nordberg A, Lemoine L. Characterization of MK6240, a tau PET tracer, in autopsy brain tissue from Alzheimer's disease cases. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32970217 DOI: 10.1007/s00259-020-05035-y   
2020 Hanes J, Kovac A, Kvartsberg H, Kontsekova E, Fialova L, Katina S, Kovacech B, Stevens E, Hort J, Vyhnalek M, Boonkamp L, Novak M, Zetterberg H, Hansson O, Scheltens P, et al. Evaluation of a novel immunoassay to detect p-Tau Thr127 in the CSF to distinguish Alzheimer disease from other dementias. Neurology. PMID 32973122 DOI: 10.1212/WNL.0000000000010814   
2020 Robison LS, Gannon OJ, Thomas MA, Salinero AE, Abi-Ghanem C, Poitelon Y, Belin S, Zuloaga KL. Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease. Journal of Neuroinflammation. 17: 285. PMID 32993686 DOI: 10.1186/s12974-020-01956-5   
2020 Perea JR, Bolós M, Avila J. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. 10. PMID 33066368 DOI: 10.3390/biom10101439   
2020 Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32975365 DOI: 10.1002/alz.12185   
2020 Meeker KL, Wisch JK, Hudson D, Coble D, Xiong C, Babulal GM, Gordon BA, Schindler SE, Cruchaga C, Flores S, Dincer A, Benzinger TL, Morris JC, Ances BM. Socioeconomic Status Mediates Racial Differences Seen Using the AT(N) Framework. Annals of Neurology. PMID 33111990 DOI: 10.1002/ana.25948   
2020 Soleimani-Meigooni DN, Iaccarino L, La Joie R, Baker S, Bourakova V, Boxer AL, Edwards L, Eser R, Gorno-Tempini ML, Jagust WJ, Janabi M, Kramer JH, Lesman-Segev OH, Mellinger T, Miller BL, et al. 18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases. Brain : a Journal of Neurology. PMID 33141172 DOI: 10.1093/brain/awaa276   
2020 Chen CD, Holden TR, Gordon BA, Franklin EE, Li Y, Coble DW, Luo H, Bateman RJ, , Ances BM, Perrin RJ, Benzinger TLS, Cairns NJ, Morris JC. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 33150749 DOI: 10.1002/acn3.51237   
2020 Barman NC, Khan NM, Islam M, Nain Z, Roy RK, Haque A, Barman SK. CRISPR-Cas9: A Promising Genome Editing Therapeutic Tool for Alzheimer's Disease-A Narrative Review. Neurology and Therapy. PMID 33089409 DOI: 10.1007/s40120-020-00218-z   
2020 Baek MS, Cho H, Lee HS, Lee JH, Ryu YH, Lyoo CH. Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease. Alzheimer's Research & Therapy. 12: 140. PMID 33129364 DOI: 10.1186/s13195-020-00710-6   
2020 Poon CH, Wang Y, Fung ML, Zhang C, Lim LW. Rodent Models of Amyloid-Beta Feature of Alzheimer's Disease: Development and Potential Treatment Implications. Aging and Disease. 11: 1235-1259. PMID 33014535 DOI: 10.14336/AD.2019.1026   
2020 Tan MS, Yang YX, Wang HF, Xu W, Tan CC, Zuo CT, Dong Q, Tan L, Yu JT, . PET Amyloid and Tau Status Are Differently Affected by Patient Features. Journal of Alzheimer's Disease : Jad. PMID 33104024 DOI: 10.3233/JAD-200124   
2020 Banks SJ, Qiu Y, Fan CC, Dale AM, Zou J, Askew B, Feldman HH, . Enriching the design of Alzheimer's disease clinical trials: Application of the polygenic hazard score and composite outcome measures. Alzheimer's & Dementia (New York, N. Y.). 6: e12071. PMID 32999917 DOI: 10.1002/trc2.12071   
2020 Sun BL, Chen Y, Fan DY, Zhu C, Zeng F, Wang YJ. Critical thinking on amyloid-beta-targeted therapy: challenges and perspectives. Science China. Life Sciences. PMID 33106917 DOI: 10.1007/s11427-020-1810-y   
2020 Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV, , , et al. Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 33046162 DOI: 10.1017/S1355617720000934   
2020 Liu M, Dexheimer T, Sui D, Hovde S, Deng X, Kwok R, Bochar DA, Kuo MH. Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions. Scientific Reports. 10: 16551. PMID 33024171 DOI: 10.1038/s41598-020-73680-2   
2020 Brooker H, Williams G, Hampshire A, Corbett A, Aarsland D, Cummings J, Molinuevo JL, Atri A, Ismail Z, Creese B, Fladby T, Thim-Hansen C, Wesnes K, Ballard C. FLAME: A computerized neuropsychological composite for trials in early dementia. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12098. PMID 33088895 DOI: 10.1002/dad2.12098   
2020 Cardoso R, Lemos C, Oliveiros B, Rosário Almeida M, Baldeiras I, Fragão Pereira C, Santos A, Duro D, Vieira D, Santana I, Resende Oliveira C. APOEɛ4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33016906 DOI: 10.3233/JAD-200556   
2020 Weuve J, D'Souza J, Beck T, Evans DA, Kaufman JD, Rajan KB, de Leon CFM, Adar SD. Long-term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33084241 DOI: 10.1002/alz.12191   
2020 Ljubic B, Roychoudhury S, Cao XH, Pavlovski M, Obradovic S, Nair R, Glass L, Obradovic Z. Influence of medical domain knowledge on deep learning for Alzheimer's disease prediction. Computer Methods and Programs in Biomedicine. 197: 105765. PMID 33011665 DOI: 10.1016/j.cmpb.2020.105765   
2020 Montero-Odasso M, Pieruccini-Faria F, Ismail Z, Li K, Lim A, Phillips N, Kamkar N, Sarquis-Adamson Y, Speechley M, Theou O, Verghese J, Wallace L, Camicioli R. CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus. Alzheimer's & Dementia (New York, N. Y.). 6: e12068. PMID 33094146 DOI: 10.1002/trc2.12068   
2020 Yu SY, Zhu WL, Guo P, Li SW, Liu YO, Lian TH, Ding DY, Li DN, Li LX, Liu L, Zhao H, Zuo LJ, Hu Y, Yu QJ, Jin Z, et al. Clinical features and brain structural changes in magnetic resonance imaging in Alzheimer's disease patients with apathy. Aging. 12. PMID 33041262 DOI: 10.18632/aging.103705   
2020 Xia Y, Yassi N, Raniga P, Bourgeat P, Desmond P, Doecke J, Ames D, Laws SM, Fowler C, Rainey-Smith SR, Martins R, Maruff P, Villemagne VL, Masters CL, Rowe CC, ... , et al. Comorbidity of Cerebrovascular and Alzheimer's Disease in Aging. Journal of Alzheimer's Disease : Jad. PMID 32986666 DOI: 10.3233/JAD-200419   
2020 Osama A, Zhang J, Yao J, Yao X, Fang J. Nrf2: a dark horse in Alzheimer's disease treatment. Ageing Research Reviews. 101206. PMID 33144124 DOI: 10.1016/j.arr.2020.101206   
2020 Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, et al. Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models. Brain Communications. 2: fcaa039. PMID 32954296 DOI: 10.1093/braincomms/fcaa039   
2020 Tagai K, Ono M, Kubota M, Kitamura S, Takahata K, Seki C, Takado Y, Shinotoh H, Sano Y, Yamamoto Y, Matsuoka K, Takuwa H, Shimojo M, Takahashi M, Kawamura K, et al. High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies. Neuron. PMID 33125873 DOI: 10.1016/j.neuron.2020.09.042   
2020 Alam J. Vitamins: a nutritional intervention to modulate the Alzheimer's disease progression. Nutritional Neuroscience. 1-18. PMID 32998670 DOI: 10.1080/1028415X.2020.1826762   
2020 Kuo CY, Stachiv I, Nikolai T. Association of Late Life Depression, (Non-) Modifiable Risk and Protective Factors with Dementia and Alzheimer's Disease: Literature Review on Current Evidences, Preventive Interventions and Possible Future Trends in Prevention and Treatment of Dementia. International Journal of Environmental Research and Public Health. 17. PMID 33066592 DOI: 10.3390/ijerph17207475   
2020 Dadar M, Camicioli R, Duchesne S, Collins DL, . The temporal relationships between white matter hyperintensities, neurodegeneration, amyloid beta, and cognition. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12091. PMID 33083512 DOI: 10.1002/dad2.12091   
2020 Josephs KA, Martin PR, Weigand SD, Tosakulwong N, Buciuc M, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Dickson DW, Jack CR, et al. Protein contributions to brain atrophy acceleration in Alzheimer's disease and primary age-related tauopathy. Brain : a Journal of Neurology. PMID 33150361 DOI: 10.1093/brain/awaa299   
2020 Petekkaya E, Burakgazi G, Kuş B, Melek İM, Arpacı A. Comparative study of the volume of the temporal lobe sections and neuropeptide effect in Alzheimer's patients and healthy persons. The International Journal of Neuroscience. 1-10. PMID 33064056 DOI: 10.1080/00207454.2020.1831490   
2020 Corbo C, Li AA, Poustchi H, Lee GY, Stacks S, Molinaro R, Ma P, Platt T, Behzadi S, Langer R, Farias V, Farokhzad OC. Analysis of the Human Plasma Proteome Using Multi-Nanoparticle Protein Corona for Detection of Alzheimer's Disease. Advanced Healthcare Materials. e2000948. PMID 33169521 DOI: 10.1002/adhm.202000948   
2020 Bubu OM, Umasabor-Bubu OQ, Turner AD, Parekh A, Mullins AE, Kam K, Birckbichler MK, Mukhtar F, Mbah AK, Williams NJ, Rapoport DM, de Leon M, Jean-Louis G, Ayappa I, Varga AW, ... , et al. Self-reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time-dependent progression. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33090679 DOI: 10.1002/alz.12184