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Lily Y. Jan - Publications

Affiliations: 
Physiology University of California, San Francisco, San Francisco, CA 
Area:
Channel Physiology
Website:
http://www.hhmi.org/scientists/lily-y-jan

406 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cheng Y, Feng S, Puchades C, Ko J, Figueroa E, Chen Y, Wu H, Gu S, Han T, Li J, Ho B, Shoichet B, Jan YN, Jan L. Identification of a conserved drug binding pocket in TMEM16 proteins. Research Square. PMID 35169791 DOI: 10.21203/rs.3.rs-1296933/v1  0.751
2021 Chou SM, Li KX, Huang MY, Chen C, Lin King YH, Li GG, Teo CF, Jan YN, Jan LY, Yang SB. Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway. Elife. 10. PMID 34018923 DOI: 10.7554/eLife.58779  0.73
2021 Wang TA, Chen C, Huang F, Feng S, Tien J, Braz JM, Basbaum AI, Jan YN, Jan LY. TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33972431 DOI: 10.1073/pnas.2023342118  0.787
2020 Petkovic M, Oses-Prieto J, Burlingame A, Jan LY, Jan YN. TMEM16K is an interorganelle regulator of endosomal sorting. Nature Communications. 11: 3298. PMID 32620747 DOI: 10.1038/S41467-020-17016-8  0.623
2020 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 9. PMID 32286221 DOI: 10.7554/Elife.53085  0.704
2020 Jin P, Jan LY, Jan YN. Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms. Annual Review of Neuroscience. PMID 32084327 DOI: 10.1146/annurev-neuro-070918-050509  0.676
2020 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li K, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. Author response: Chloride channels regulate differentiation and barrier functions of the mammalian airway Elife. DOI: 10.7554/Elife.53085.Sa2  0.546
2019 Piggott BJ, Peters CJ, He Y, Huang X, Younger S, Jan LY, Jan YN. Paralytic, the voltage-gated sodium channel, regulates proliferation of neural progenitors. Genes & Development. PMID 31753914 DOI: 10.1101/Gad.330597.119  0.766
2019 Li KX, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY. TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala. Elife. 8. PMID 31482844 DOI: 10.7554/Elife.47106  0.693
2019 Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Reports. 28: 1385. PMID 31365878 DOI: 10.2210/Pdb6P48/Pdb  0.807
2019 Wang L, Simms J, Peters CJ, Fontaine MT, Li K, Gill TM, Nung Jan Y, Jan LY. TMEM16B calcium-activated chloride channels regulate action potential firing in lateral septum and aggression in male mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31320449 DOI: 10.1523/Jneurosci.3137-18.2019  0.778
2019 Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. Thermoregulation via Temperature-Dependent PGD Production in Mouse Preoptic Area. Neuron. 103: 349. PMID 31319050 DOI: 10.1016/j.neuron.2019.06.026  0.749
2019 Ye W, Han TW, He M, Jan YN, Jan LY. Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. Elife. 8. PMID 31318330 DOI: 10.7554/Elife.45187  0.808
2019 Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Reports. 28: 567-579.e4. PMID 31291589 DOI: 10.1016/j.celrep.2019.06.023  0.784
2019 Crottès D, Lin YT, Peters CJ, Gilchrist JM, Wiita AP, Jan YN, Jan LY. TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182586 DOI: 10.1073/Pnas.1900703116  0.672
2019 Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. Thermoregulation via Temperature-Dependent PGD Production in Mouse Preoptic Area. Neuron. PMID 31151773 DOI: 10.1016/J.Neuron.2019.04.035  0.793
2019 Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, ... ... Jan LY, et al. The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration. Neuron. PMID 30819546 DOI: 10.1016/J.Neuron.2019.01.050  0.652
2019 Yadav S, Younger SH, Zhang L, Thompson-Peer KL, Li T, Jan LY, Jan YN. Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30804200 DOI: 10.1073/Pnas.1814456116  0.647
2019 Han TW, Ye W, Bethel NP, Zubia M, Kim A, Li KH, Burlingame AL, Grabe M, Jan YN, Jan LY. Chemically induced vesiculation as a platform for studying TMEM16F activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30622179 DOI: 10.1073/Pnas.1817498116  0.784
2019 Li K, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY. Author response: TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala Elife. DOI: 10.7554/Elife.47106.017  0.468
2019 Ye W, Han TW, He M, Jan YN, Jan LY. Author response: Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity Elife. DOI: 10.7554/Elife.45187.025  0.453
2019 Attali B, Chandy KG, Giese MH, Grissmer S, Gutman GA, Jan LY, Lazdunski M, Mckinnon D, Nerbonne J, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Trimmer JS, et al. Voltage-gated potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f81/2019.4  0.316
2019 Adelman JP, Clapham DE, Hibino H, Inanobe A, Jan LY, Karschin A, Kubo Y, Kurachi Y, Lazdunski M, Miki T, Nichols CG, Palmer LG, Pearson WL, Sackin H, Seino S, et al. Inwardly rectifying potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f74/2019.4  0.635
2018 Jan YN, Jan LY. Force-activated ion channels in close-up. Nature. 554: 469-470. PMID 32094930 DOI: 10.1038/d41586-018-01631-z  0.627
2018 Zhou W, Cheung K, Kyu S, Wang L, Guan Z, Kurien PA, Bickler PE, Jan LY. Activation of orexin system facilitates anesthesia emergence and pain control. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348769 DOI: 10.1073/Pnas.1808622115  0.712
2018 Jan LY, Jan YN. Influences: Cold Spring Harbor summer courses and neurogenetics. The Journal of General Physiology. PMID 29769227 DOI: 10.1085/jgp.201812063  0.552
2018 DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan LY, Jan YN. Dendrite regeneration of adultsensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes & Development. 32: 402-414. PMID 29563183 DOI: 10.1101/Gad.308270.117  0.63
2018 Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. PMID 29478917 DOI: 10.1016/J.Neuron.2018.01.048  0.818
2018 Jan YN, Jan LY. Force-activated ion channels in close-up. Nature. 554: 469-470. PMID 29469134 DOI: 10.1038/d41586-018-01631-z  0.612
2018 Ye W, Han TW, Nassar LM, Zubia M, Jan YN, Jan LY. Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proceedings of the National Academy of Sciences of the United States of America. PMID 29382763 DOI: 10.1073/Pnas.1718728115  0.808
2018 Han TW, Ye W, Bethel NP, Zubia M, Grabe M, Nung Jan Y, Jan LY. TMEM16F is a Calcium-Activated Phospholipid Scramblase Required for Chemically-Induced Giant Plasma Membrane Vesicles Biophysical Journal. 114: 610a. DOI: 10.1016/J.Bpj.2017.11.3335  0.76
2018 Ye W, Han TW, Nassar LM, Zubia M, Nung Jan Y, Jan LY. Phosphatidylinositol-(4,5)-Bisphosphate is a Necessary Cofactor for TMEM16F Ion Channel Activities Biophysical Journal. 114: 494a. DOI: 10.1016/J.Bpj.2017.11.2707  0.762
2017 He M, Ye W, Wang WJ, Sison ES, Jan YN, Jan LY. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229864 DOI: 10.1073/Pnas.1714448115  0.696
2017 Meltzer S, Bagley JA, Perez GL, O'Brien CE, DeVault L, Guo Y, Jan LY, Jan YN. Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. Cell Reports. 21: 859-866. PMID 29069593 DOI: 10.1016/J.Celrep.2017.09.089  0.72
2017 Zhang Y, Zhang Z, Xiao S, Tien J, Le S, Le T, Jan LY, Yang H. Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. Neuron. 95: 1103-1111.e4. PMID 28858616 DOI: 10.1016/J.Bpj.2017.11.752  0.769
2017 Orr BO, Gorczyca D, Younger MA, Jan LY, Jan YN, Davis GW. Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity. Cell Reports. 20: 1855-1866. PMID 28834749 DOI: 10.1016/J.Celrep.2017.07.074  0.699
2017 Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan LY, Jan YN, Cheng Y. Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. PMID 28658211 DOI: 10.1038/Nature22981  0.749
2017 Klassen MP, Peters CJ, Zhou S, Williams HH, Jan LY, Jan YN. Age-dependent diastolic heart failure in an in vivo Drosophila model. Elife. 6. PMID 28328397 DOI: 10.7554/Elife.20851  0.673
2017 Klassen MP, Peters CJ, Zhou S, Williams HH, Jan LY, Jan YN. Author response: Age-dependent diastolic heart failure in an in vivo Drosophila model Elife. DOI: 10.7554/Elife.20851.029  0.426
2017 Peters CJ, Chen T, Tien J, Nung Jan Y, Jan L. Identification of Critical Residues for Anion Conductance in the TMEM16A Channel Biophysical Journal. 112: 173a. DOI: 10.1016/J.Bpj.2016.11.955  0.75
2016 Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY, Jan YN. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. PMID 28065648 DOI: 10.1016/J.Neuron.2016.12.006  0.678
2016 Li J, Zhang W, Guo Z, Wu S, Jan LY, Jan YN. A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11275-11282. PMID 27807168 DOI: 10.1523/Jneurosci.1416-16.2016  0.626
2016 Thompson-Peer KL, DeVault L, Li T, Jan LY, Jan YN. In vivo dendrite regeneration after injury is different from dendrite development. Genes & Development. 30: 1776-89. PMID 27542831 DOI: 10.1101/Gad.282848.116  0.622
2016 Thayer DA, Yang SB, Jan YN, Jan LY. N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances stability of internalized channels. The Journal of Physiology. PMID 27377235 DOI: 10.1113/Jp272394  0.759
2016 Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Göpfert MC, Jan LY, et al. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298354 DOI: 10.1073/Pnas.1606537113  0.747
2016 Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. PMID 27112495 DOI: 10.1016/J.Neuron.2016.03.027  0.701
2016 Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan YN. Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons. Neuron. PMID 26853303 DOI: 10.1016/J.Neuron.2016.01.020  0.704
2015 Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A, Dell'Accio F, Pitzalis C, Oliani SM, Jan LY, Perretti M. Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. Science Translational Medicine. 7: 315ra190. PMID 26606969 DOI: 10.1126/Scitranslmed.Aac5608  0.51
2015 Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan LY, Jan YN. Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell. 162: 1391-403. PMID 26359990 DOI: 10.1016/J.Cell.2015.08.024  0.698
2015 Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, ... ... Jan LY, et al. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nature Neuroscience. PMID 26258683 DOI: 10.1038/Nn.4088  0.815
2015 Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Xiong X, Meltzer S, Han C, Nguyen TT, Bresnahan JC, Beattie MS, Jan LY, Jan YN. Regulation of axon regeneration by the RNA repair and splicing pathway. Nature Neuroscience. 18: 817-25. PMID 25961792 DOI: 10.1038/Nn.4019  0.714
2015 Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan LY, Jan YN. The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife. 4. PMID 25764303 DOI: 10.7554/Elife.05491  0.644
2015 Peters CJ, Yu H, Tien J, Jan YN, Li M, Jan LY. Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proceedings of the National Academy of Sciences of the United States of America. 112: 3547-52. PMID 25733897 DOI: 10.1073/Pnas.1502291112  0.787
2015 Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan LY, Fu YH, Ptá?ek LJ. Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2935-41. PMID 25730884 DOI: 10.1073/Pnas.1501364112  0.526
2015 Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan LY, Jan YN. Author response: The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion Elife. DOI: 10.7554/Elife.05491.018  0.315
2014 Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan YN. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Neuron. 84: 968-82. PMID 25456499 DOI: 10.1016/J.Neuron.2014.10.025  0.611
2014 Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan LY, Jan YN. Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Reports. 9: 1446-58. PMID 25456135 DOI: 10.1016/J.Celrep.2014.10.034  0.758
2014 Zhang W, Yan Z, Li B, Jan LY, Jan YN. Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae. Elife. 3. PMID 25358089 DOI: 10.7554/eLife.03293  0.642
2014 Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, Eitson JL, Hollegaard MV, Svanström H, Vestergaard M, Hougaard DM, Schoggins JW, Jan LY, Melbye M, Hviid A. Common variants associated with general and MMR vaccine-related febrile seizures. Nature Genetics. 46: 1274-82. PMID 25344690 DOI: 10.1038/Ng.3129  0.692
2014 Bagley JA, Yan Z, Zhang W, Wildonger J, Jan LY, Jan YN. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes & Development. 28: 1940-56. PMID 25184680 DOI: 10.1101/Gad.239962.114  0.678
2014 Huang X, Jan LY. Targeting potassium channels in cancer. The Journal of Cell Biology. 206: 151-62. PMID 25049269 DOI: 10.1085/Jgp.1442Oia34  0.559
2014 Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 3. PMID 24980701 DOI: 10.7554/Elife.02772  0.811
2014 Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nature Medicine. 20: 624-32. PMID 24836577 DOI: 10.1038/Nm.3543  0.669
2014 Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nature Communications. 5: 3626. PMID 24832154 DOI: 10.1038/Ncomms4626  0.615
2014 Parrish JZ, Kim CC, Tang L, Bergquist S, Wang T, Derisi JL, Jan LY, Jan YN, Davis GW. Krüppel mediates the selective rebalancing of ion channel expression. Neuron. 82: 537-44. PMID 24811378 DOI: 10.1016/J.Neuron.2014.03.015  0.826
2014 Rumpf S, Bagley JA, Thompson-Peer KL, Zhu S, Gorczyca D, Beckstead RB, Jan LY, Jan YN. Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. Proceedings of the National Academy of Sciences of the United States of America. 111: 7331-6. PMID 24799714 DOI: 10.1073/Pnas.1406898111  0.644
2014 Han C, Song Y, Xiao H, Wang D, Franc NC, Jan LY, Jan YN. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 81: 544-60. PMID 24412417 DOI: 10.1016/J.Neuron.2013.11.021  0.634
2014 Yuan Q, Song Y, Yang CH, Jan LY, Jan YN. Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nature Neuroscience. 17: 81-8. PMID 24241395 DOI: 10.1038/Nn.3581  0.601
2014 Zhang W, Yan Z, Li B, Jan LY, Jan YN. Author response: Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae Elife. DOI: 10.7554/Elife.03293.029  0.302
2014 Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. Author response: A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity Elife. DOI: 10.7554/Elife.02772.012  0.788
2014 Tien J, Young DM, Jan YN, Jan LY. Molecular Properties of Ion Channels From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition. 323-348. DOI: 10.1016/B978-0-12-397179-1.00011-7  0.737
2013 Kim WJ, Jan LY, Jan YN. A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating. Neuron. 80: 1190-205. PMID 24314729 DOI: 10.1016/j.neuron.2013.09.034  0.628
2013 Wong XM, Younger S, Peters CJ, Jan YN, Jan LY. Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2: e00862. PMID 24192034 DOI: 10.7554/Elife.00862  0.812
2013 Isacoff EY, Jan LY, Minor DL. Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron. 80: 658-74. PMID 24183018 DOI: 10.1016/J.Neuron.2013.10.040  0.718
2013 Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2: e00508. PMID 24040509 DOI: 10.7554/Elife.00508  0.309
2013 Zhang W, Yan Z, Jan LY, Jan YN. Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proceedings of the National Academy of Sciences of the United States of America. 110: 13612-7. PMID 23898199 DOI: 10.1073/pnas.1312477110  0.662
2013 Han TW, Jan LY. Making antisense of pain. Nature Neuroscience. 16: 986-7. PMID 23887131 DOI: 10.1038/nn.3475  0.682
2013 Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan LY. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nature Neuroscience. 16: 1284-90. PMID 23872594 DOI: 10.1038/Nn.3468  0.693
2013 Tien J, Lee HY, Minor DL, Jan YN, Jan LY. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proceedings of the National Academy of Sciences of the United States of America. 110: 6352-7. PMID 23576756 DOI: 10.1073/Pnas.1303672110  0.827
2013 Thayer DA, Jan YN, Jan LY. Increased neuronal activity fragments the Golgi complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 1482-7. PMID 23297202 DOI: 10.1073/Pnas.1220978110  0.639
2013 Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan LY, Jan YN. Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature. 493: 221-5. PMID 23222543 DOI: 10.1038/Nature11685  0.768
2013 Wong XM, Younger S, Peters CJ, Jan YN, Jan LY. Author response: Subdued, a TMEM16 family Ca2+-activated Cl− channel in Drosophila melanogaster with an unexpected role in host defense Elife. DOI: 10.7554/Elife.00862.012  0.798
2013 Wong XM, Younger S, Peters CJ, Jan YN, Jan LY. Subdued, a TMEM16 family Ca2+-activated Cl- channel in Drosophila melanogaster with an unexpected role in host defense Elife. 2013. DOI: 10.7554/eLife.00862.001  0.799
2012 Ori-McKenney KM, Jan LY, Jan YN. Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron. 76: 921-30. PMID 23217741 DOI: 10.1016/j.neuron.2012.10.008  0.639
2012 Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan LY. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell. 151: 111-22. PMID 23021219 DOI: 10.1016/J.Bpj.2012.11.2033  0.796
2012 Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, ... ... Jan LY, et al. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 109: 16354-9. PMID 22988107 DOI: 10.1073/Pnas.1214596109  0.8
2012 Yang SB, Tien AC, Boddupalli G, Xu AW, Jan YN, Jan LY. Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron. 75: 425-36. PMID 22884327 DOI: 10.1016/J.Neuron.2012.03.043  0.708
2012 Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, ... ... Jan LY, et al. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes & Development. 26: 1780-96. PMID 22855790 DOI: 10.1101/Gad.193789.112  0.765
2012 Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan LY, Jan YN. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes & Development. 26: 1612-25. PMID 22759636 DOI: 10.1101/Gad.193243.112  0.625
2012 Kim WJ, Jan LY, Jan YN. Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. Nature Neuroscience. 15: 876-83. PMID 22561453 DOI: 10.1038/nn.3104  0.594
2012 Berg J, Yang H, Jan LY. Ca2+-activated Cl- channels at a glance. Journal of Cell Science. 125: 1367-71. PMID 22526416 DOI: 10.1242/jcs.093260  0.647
2012 Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron. 74: 179-92. PMID 22500639 DOI: 10.1016/j.neuron.2012.01.033  0.668
2012 Lee HY, Jan LY. Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels. Current Opinion in Neurobiology. 22: 887-94. PMID 22483378 DOI: 10.1016/j.conb.2012.03.010  0.361
2012 Ge WP, Miyawaki A, Gage FH, Jan YN, Jan LY. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 484: 376-80. PMID 22456708 DOI: 10.1038/nature10959  0.604
2012 Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 73: 1127-42. PMID 22445341 DOI: 10.1016/J.Neuron.2012.01.019  0.643
2012 Jan LY, Jan YN. Voltage-gated potassium channels and the diversity of electrical signalling. The Journal of Physiology. 590: 2591-9. PMID 22431339 DOI: 10.1113/jphysiol.2011.224212  0.705
2012 Yang SB, Mclemore KD, Tasic B, Luo L, Jan YN, Jan LY. Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers. The Journal of Physiology. 590: 2645-58. PMID 22411008 DOI: 10.1113/Jphysiol.2012.228486  0.727
2012 Han C, Wang D, Soba P, Zhu S, Lin X, Jan LY, Jan YN. Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space. Neuron. 73: 64-78. PMID 22243747 DOI: 10.1016/J.Neuron.2011.10.036  0.638
2012 Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan YN, Jan LY. Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. Journal of Molecular Medicine (Berlin, Germany). 90: 575-85. PMID 22105852 DOI: 10.1007/S00109-011-0834-3  0.651
2012 Huang F, Wong X, Jan LY. International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacological Reviews. 64: 1-15. PMID 22090471 DOI: 10.1124/pr.111.005009  0.416
2012 Kim AY, Yang H, David T, Tien J, Coughlin SR, Jan YN, Jan L. TMEM16F Ion Channel Regulates Calcium-Dependent PS Exposure, Hemostasis, and Thrombosis Blood. 120: 1111-1111. DOI: 10.1182/Blood.V120.21.1111.1111  0.799
2011 Zhu S, Barshow S, Wildonger J, Jan LY, Jan YN. Ets transcription factor Pointed promotes the generation of intermediate neural progenitors in Drosophila larval brains. Proceedings of the National Academy of Sciences of the United States of America. 108: 20615-20. PMID 22143802 DOI: 10.1073/Pnas.1118595109  0.611
2011 Lee HY, Ge WP, Huang W, He Y, Wang GX, Rowson-Baldwin A, Smith SJ, Jan YN, Jan LY. Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron. 72: 630-42. PMID 22099464 DOI: 10.1016/J.Neuron.2011.09.033  0.69
2011 Lee SB, Bagley JA, Lee HY, Jan LY, Jan YN. Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 108: 16795-800. PMID 21930920 DOI: 10.1073/pnas.1113573108  0.651
2011 Yuan Q, Xiang Y, Yan Z, Han C, Jan LY, Jan YN. Light-induced structural and functional plasticity in Drosophila larval visual system. Science (New York, N.Y.). 333: 1458-62. PMID 21903815 DOI: 10.1126/Science.1207121  0.628
2011 Lee RM, Ryu RH, Jeong SW, Oh SJ, Huang H, Han JS, Lee CH, Lee CJ, Jan LY, Jeong SM. Isolation and Expression Profile of the Ca-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis. Laboratory Animal Research. 27: 109-16. PMID 21826170 DOI: 10.5625/lar.2011.27.2.109  0.386
2011 Han C, Jan LY, Jan YN. Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 108: 9673-8. PMID 21606367 DOI: 10.1073/Pnas.1106386108  0.652
2011 Ouyang Y, Petritsch C, Wen H, Jan L, Jan YN, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development (Cambridge, England). 138: 2185-96. PMID 21558368 DOI: 10.1242/Dev.058347  0.623
2011 Ryu RH, Oh SJ, Lee RM, Jeong SW, Jan LY, Lee CH, Lee CJ, Jeong SM. Cloning and heterologous expression of new xANO2 from Xenopus laevis. Biochemical and Biophysical Research Communications. 408: 559-65. PMID 21521635 DOI: 10.1016/j.bbrc.2011.04.060  0.344
2011 Ye B, Kim JH, Yang L, McLachlan I, Younger S, Jan LY, Jan YN. Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3309-19. PMID 21368042 DOI: 10.1523/Jneurosci.6307-10.2011  0.635
2011 Rumpf S, Lee SB, Jan LY, Jan YN. Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development (Cambridge, England). 138: 1153-60. PMID 21343367 DOI: 10.1242/dev.062703  0.635
2011 Yang H, Jin T, Cheng T, Jan YN, Jan LY. Scan: A Novel Small-Conductance Ca2+-Activated Non-Selective Cation Channel Encoded by TMEM16F Biophysical Journal. 100: 259a. DOI: 10.1016/J.Bpj.2010.12.1631  0.772
2010 Xiang Y, Yuan Q, Vogt N, Looger LL, Jan LY, Jan YN. Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature. 468: 921-6. PMID 21068723 DOI: 10.1038/nature09576  0.614
2010 Cheng LE, Song W, Looger LL, Jan LY, Jan YN. The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron. 67: 373-80. PMID 20696376 DOI: 10.1016/j.neuron.2010.07.004  0.69
2010 Zhou W, Jan L. A twist on potassium channel gating. Cell. 141: 920-2. PMID 20550927 DOI: 10.1016/j.cell.2010.05.038  0.395
2010 Young DM, Schenk AK, Yang SB, Jan YN, Jan LY. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proceedings of the National Academy of Sciences of the United States of America. 107: 11074-9. PMID 20534473 DOI: 10.1073/Pnas.1005620107  0.66
2010 Jan YN, Jan LY. Branching out: mechanisms of dendritic arborization. Nature Reviews. Neuroscience. 11: 316-28. PMID 20404840 DOI: 10.1038/nrn2836  0.644
2009 Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 21413-8. PMID 19965375 DOI: 10.1073/Pnas.0911935106  0.696
2009 Parrish JZ, Xu P, Kim CC, Jan LY, Jan YN. The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron. 63: 788-802. PMID 19778508 DOI: 10.1016/J.Neuron.2009.08.006  0.639
2009 Bultje RS, Castaneda-Castellanos DR, Jan LY, Jan YN, Kriegstein AR, Shi SH. Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron. 63: 189-202. PMID 19640478 DOI: 10.1016/J.Neuron.2009.07.004  0.714
2009 Lee HH, Jan LY, Jan YN. Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 6363-8. PMID 19329489 DOI: 10.1073/pnas.0902051106  0.639
2009 Yang CH, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, Jan YN. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 61: 519-26. PMID 19249273 DOI: 10.1016/j.neuron.2008.12.021  0.609
2009 Chung HJ, Ge WP, Qian X, Wiser O, Jan YN, Jan LY. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 106: 635-40. PMID 19118199 DOI: 10.1073/Pnas.0811685106  0.753
2009 Chung HJ, Qian X, Ehlers M, Jan YN, Jan LY. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 629-34. PMID 19118198 DOI: 10.1073/Pnas.0811615106  0.782
2009 Ge WP, Zhou W, Luo Q, Jan LY, Jan YN. Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proceedings of the National Academy of Sciences of the United States of America. 106: 328-33. PMID 19104058 DOI: 10.1073/Pnas.0811353106  0.644
2008 Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell. 134: 1019-29. PMID 18805094 DOI: 10.1016/j.cell.2008.09.003  0.68
2008 Wildonger J, Jan LY, Jan YN. The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels. Genes & Development. 22: 2447-53. PMID 18794342 DOI: 10.1101/gad.1724108  0.637
2008 Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan LY, Jan YN. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nature Cell Biology. 10: 1172-80. PMID 18758451 DOI: 10.1038/Ncb1777  0.622
2008 Jin T, Sui JL, Rosenhouse-Dantsker A, Chan KW, Jan LY, Logothetis DE. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate. Channels (Austin, Tex.). 2: 19-33. PMID 18690051 DOI: 10.4161/Chan.2.1.5942  0.446
2008 Yang SB, Jan LY. Thrilling moment of an inhibitory channel. Neuron. 58: 823-4. PMID 18579071 DOI: 10.1016/j.neuron.2008.06.003  0.608
2008 Yang CH, Belawat P, Hafen E, Jan LY, Jan YN. Drosophila egg-laying site selection as a system to study simple decision-making processes. Science (New York, N.Y.). 319: 1679-83. PMID 18356529 DOI: 10.1126/Science.1151842  0.586
2008 Jan YN, Jan L. Retrospective: Seymour Benzer (1921-2007). Science (New York, N.Y.). 319: 45. PMID 18174427 DOI: 10.1126/science.1154050  0.562
2008 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions (DOI:10.1016/j.cell.2006.12.037) Cell. 133: 376. DOI: 10.1016/J.Cell.2008.03.023  0.78
2007 Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 104: 18079-84. PMID 17989219 DOI: 10.1073/Pnas.0708765104  0.828
2007 Ye B, Zhang Y, Song W, Younger SH, Jan LY, Jan YN. Growing dendrites and axons differ in their reliance on the secretory pathway. Cell. 130: 717-29. PMID 17719548 DOI: 10.1016/J.Cell.2007.06.032  0.622
2007 Chang W, Tu C, Cheng Z, Rodriguez L, Chen TH, Gassmann M, Bettler B, Margeta M, Jan LY, Shoback D. Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. The Journal of Biological Chemistry. 282: 25030-40. PMID 17591780 DOI: 10.1074/Jbc.M700924200  0.655
2007 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nature Neuroscience. 10: 819-27. PMID 17589506 DOI: 10.1038/nn1924  0.616
2007 Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan YN. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron. 54: 403-16. PMID 17481394 DOI: 10.1016/J.Neuron.2007.03.029  0.635
2007 Parrish JZ, Emoto K, Jan LY, Jan YN. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes & Development. 21: 956-72. PMID 17437999 DOI: 10.1101/gad.1514507  0.649
2007 Song W, Onishi M, Jan LY, Jan YN. Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proceedings of the National Academy of Sciences of the United States of America. 104: 5199-204. PMID 17360325 DOI: 10.1073/pnas.0700895104  0.617
2007 Gong Q, Weide M, Huntsman C, Xu Z, Jan LY, Ma D. Identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling. The Journal of Biological Chemistry. 282: 13087-97. PMID 17331948 DOI: 10.1074/Jbc.M700767200  0.415
2007 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 128: 547-60. PMID 17289573 DOI: 10.1016/J.Cell.2006.12.037  0.797
2007 Grabe M, Lai HC, Jain M, Jan YN, Jan LY. Structure prediction for the down state of a potassium channel voltage sensor. Nature. 445: 550-3. PMID 17187053 DOI: 10.1038/Nature05494  0.786
2007 Grueber WB, Ye B, Yang CH, Younger S, Borden K, Jan LY, Jan YN. Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development (Cambridge, England). 134: 55-64. PMID 17164414 DOI: 10.1242/dev.02666  0.786
2006 Chung HJ, Jan LY. Channeling to the nucleus. Neuron. 52: 937-40. PMID 17178398 DOI: 10.1016/J.Neuron.2006.12.001  0.624
2006 Kuo CT, Mirzadeh Z, Soriano-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan LY, Jan YN. Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 127: 1253-64. PMID 17174898 DOI: 10.1016/J.Cell.2006.10.041  0.679
2006 Ja WW, Wiser O, Austin RJ, Jan LY, Roberts RW. Turning G proteins on and off using peptide ligands. Acs Chemical Biology. 1: 570-4. PMID 17168552 DOI: 10.1021/Cb600345K  0.325
2006 Gu C, Zhou W, Puthenveedu MA, Xu M, Jan YN, Jan LY. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 52: 803-16. PMID 17145502 DOI: 10.1016/J.Neuron.2006.10.022  0.667
2006 Fay AJ, Qian X, Jan YN, Jan LY. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 17548-53. PMID 17085590 DOI: 10.1073/Pnas.0607914103  0.8
2006 Ye B, Zhang YW, Jan LY, Jan YN. The secretory pathway and neuron polarization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10631-2. PMID 17050701 DOI: 10.1523/JNEUROSCI.3271-06.2006  0.616
2006 Raab-Graham KF, Haddick PC, Jan YN, Jan LY. Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science (New York, N.Y.). 314: 144-8. PMID 17023663 DOI: 10.1126/Science.1131693  0.811
2006 Kim MD, Jan LY, Jan YN. The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes & Development. 20: 2806-19. PMID 17015425 DOI: 10.1101/gad.1459706  0.643
2006 Bichet D, Grabe M, Jan YN, Jan LY. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 14355-60. PMID 16983069 DOI: 10.1073/Pnas.0606660103  0.74
2006 Grabe M, Bichet D, Qian X, Jan YN, Jan LY. K+ channel selectivity depends on kinetic as well as thermodynamic factors. Proceedings of the National Academy of Sciences of the United States of America. 103: 14361-6. PMID 16983068 DOI: 10.1073/Pnas.0606662103  0.736
2006 Emoto K, Parrish JZ, Jan LY, Jan YN. The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature. 443: 210-3. PMID 16906135 DOI: 10.1038/nature05090  0.639
2006 Kuo CT, Zhu S, Younger S, Jan LY, Jan YN. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron. 51: 283-90. PMID 16880123 DOI: 10.1016/J.Neuron.2006.07.014  0.707
2006 Lai HC, Jan LY. The distribution and targeting of neuronal voltage-gated ion channels. Nature Reviews. Neuroscience. 7: 548-62. PMID 16791144 DOI: 10.1038/Nrn1938  0.666
2006 Chung HJ, Jan YN, Jan LY. Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proceedings of the National Academy of Sciences of the United States of America. 103: 8870-5. PMID 16735477 DOI: 10.1073/Pnas.0603376103  0.768
2006 Wiser O, Qian X, Ehlers M, Ja WW, Roberts RW, Reuveny E, Jan YN, Jan LY. Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron. 50: 561-73. PMID 16701207 DOI: 10.1016/J.Neuron.2006.03.046  0.808
2006 Parrish JZ, Kim MD, Jan LY, Jan YN. Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes & Development. 20: 820-35. PMID 16547170 DOI: 10.1101/gad.1391006  0.636
2005 Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacological Reviews. 57: 509-26. PMID 16382105 DOI: 10.1124/Pr.57.4.11  0.412
2005 Surti TS, Huang L, Jan YN, Jan LY, Cooper EC. Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proceedings of the National Academy of Sciences of the United States of America. 102: 17828-33. PMID 16319223 DOI: 10.1073/Pnas.0509122102  0.831
2005 Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan LY. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 123: 105-18. PMID 16213216 DOI: 10.1016/J.Cell.2005.07.033  0.706
2005 Kuo CT, Jan LY, Jan YN. Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 15230-5. PMID 16210248 DOI: 10.1073/pnas.0507393102  0.718
2005 Lai HC, Grabe M, Jan YN, Jan LY. The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel. Neuron. 47: 395-406. PMID 16055063 DOI: 10.1016/J.Neuron.2005.06.019  0.783
2005 Surti TS, Jan LY. A potassium channel, the M-channel, as a therapeutic target. Current Opinion in Investigational Drugs (London, England : 2000). 6: 704-11. PMID 16044666  0.782
2005 Ionescu-Zanetti C, Shaw RM, Seo J, Jan YN, Jan LY, Lee LP. Mammalian electrophysiology on a microfluidic platform. Proceedings of the National Academy of Sciences of the United States of America. 102: 9112-7. PMID 15967996 DOI: 10.1073/Pnas.0503418102  0.62
2005 Roegiers F, Jan LY, Jan YN. Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Molecular Biology of the Cell. 16: 3480-7. PMID 15901829 DOI: 10.1091/mbc.E05-03-0177  0.641
2005 Cohen BE, Pralle A, Yao X, Swaminath G, Gandhi CS, Jan YN, Kobilka BK, Isacoff EY, Jan LY. A fluorescent probe designed for studying protein conformational change. Proceedings of the National Academy of Sciences of the United States of America. 102: 965-70. PMID 15657131 DOI: 10.1073/Pnas.0409469102  0.778
2005 Huang EJ, Li H, Tang AA, Wiggins AK, Neve RL, Zhong W, Jan LY, Jan YN. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes & Development. 19: 138-51. PMID 15598981 DOI: 10.1101/Gad.1246005  0.789
2005 Lee PJ, Hung PJ, Shaw R, Jan L, Lee LP. Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs Applied Physics Letters. 86: 1-3. DOI: 10.1063/1.1938253  0.315
2004 Grabe M, Lecar H, Jan YN, Jan LY. A quantitative assessment of models for voltage-dependent gating of ion channels. Proceedings of the National Academy of Sciences of the United States of America. 101: 17640-5. PMID 15591352 DOI: 10.1073/Pnas.0408116101  0.734
2004 Shi SH, Cheng T, Jan LY, Jan YN. APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Current Biology : Cb. 14: 2025-32. PMID 15556865 DOI: 10.1016/J.Cub.2004.11.009  0.709
2004 Emoto K, He Y, Ye B, Grueber WB, Adler PN, Jan LY, Jan YN. Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons. Cell. 119: 245-56. PMID 15479641 DOI: 10.1016/j.cell.2004.09.036  0.788
2004 Shi SH, Cox DN, Wang D, Jan LY, Jan YN. Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1). Proceedings of the National Academy of Sciences of the United States of America. 101: 13341-5. PMID 15340157 DOI: 10.1073/Pnas.0405370101  0.713
2004 Shi SH, Cheng T, Jan LY, Jan YN. The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation. Proceedings of the National Academy of Sciences of the United States of America. 101: 13346-51. PMID 15340156 DOI: 10.1073/Pnas.0405371101  0.696
2004 Lin YF, Raab-Graham K, Jan YN, Jan LY. NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection. Proceedings of the National Academy of Sciences of the United States of America. 101: 7799-804. PMID 15136749 DOI: 10.1073/Pnas.0402496101  0.801
2004 Moore AW, Roegiers F, Jan LY, Jan YN. Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification. Genes & Development. 18: 623-8. PMID 15075290 DOI: 10.1101/gad.1170904  0.641
2004 Bichet D, Lin YF, Ibarra CA, Huang CS, Yi BA, Jan YN, Jan LY. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proceedings of the National Academy of Sciences of the United States of America. 101: 4441-6. PMID 15070737 DOI: 10.1073/Pnas.0401195101  0.747
2004 Ye B, Petritsch C, Clark IE, Gavis ER, Jan LY, Jan YN. Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Current Biology : Cb. 14: 314-21. PMID 14972682 DOI: 10.1016/J.Cub.2004.01.052  0.638
2003 Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY, Jan YN. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron. 40: 1105-18. PMID 14687546 DOI: 10.1016/S0896-6273(03)00755-4  0.611
2003 Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, et al. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacological Reviews. 55: 583-6. PMID 14657415 DOI: 10.1124/Pr.55.4.9  0.645
2003 Bichet D, Haass FA, Jan LY. Merging functional studies with structures of inward-rectifier K(+) channels. Nature Reviews. Neuroscience. 4: 957-67. PMID 14618155 DOI: 10.1038/Nrn1244  0.818
2003 Hong Y, Ackerman L, Jan LY, Jan YN. Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture. Proceedings of the National Academy of Sciences of the United States of America. 100: 12712-7. PMID 14569003 DOI: 10.1073/pnas.2135347100  0.613
2003 Jan YN, Jan LY. The control of dendrite development. Neuron. 40: 229-42. PMID 14556706 DOI: 10.1016/S0896-6273(03)00631-7  0.64
2003 Rothenberg ME, Rogers SL, Vale RD, Jan LY, Jan YN. Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons. Neuron. 39: 779-91. PMID 12948445 DOI: 10.1016/S0896-6273(03)00508-7  0.609
2003 Cohen BE, Grabe M, Jan LY. Answers and questions from the KvAP structures. Neuron. 39: 395-400. PMID 12895415 DOI: 10.1016/S0896-6273(03)00472-0  0.714
2003 Gu C, Jan YN, Jan LY. A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science (New York, N.Y.). 301: 646-9. PMID 12893943 DOI: 10.1126/Science.1086998  0.625
2003 Pei L, Wiser O, Slavin A, Mu D, Powers S, Jan LY, Hoey T. Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proceedings of the National Academy of Sciences of the United States of America. 100: 7803-7. PMID 12782791 DOI: 10.1073/Pnas.1232448100  0.339
2003 Hu K, Huang CS, Jan YN, Jan LY. ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron. 38: 417-32. PMID 12741989 DOI: 10.1016/S0896-6273(03)00256-3  0.676
2003 Justice N, Roegiers F, Jan LY, Jan YN. Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Current Biology : Cb. 13: 778-83. PMID 12725738 DOI: 10.1016/S0960-9822(03)00288-4  0.636
2003 Cooper EC, Jan LY. M-channels: neurological diseases, neuromodulation, and drug development. Archives of Neurology. 60: 496-500. PMID 12707061 DOI: 10.1001/archneur.60.4.496  0.592
2003 Grueber WB, Ye B, Moore AW, Jan LY, Jan YN. Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Current Biology : Cb. 13: 618-26. PMID 12699617 DOI: 10.1016/S0960-9822(03)00207-0  0.781
2003 Grueber WB, Jan LY, Jan YN. Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell. 112: 805-18. PMID 12654247 DOI: 10.1016/S0092-8674(03)00160-0  0.787
2003 Petritsch C, Tavosanis G, Turck CW, Jan LY, Jan YN. The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Developmental Cell. 4: 273-81. PMID 12586070 DOI: 10.1016/S1534-5807(03)00020-0  0.622
2003 Shi SH, Jan LY, Jan YN. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell. 112: 63-75. PMID 12526794 DOI: 10.1016/S0092-8674(02)01249-7  0.709
2002 Moore AW, Jan LY, Jan YN. hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. Science (New York, N.Y.). 297: 1355-8. PMID 12193790 DOI: 10.1126/science.1072387  0.636
2002 Grueber WB, Jan LY, Jan YN. Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development (Cambridge, England). 129: 2867-78. PMID 12050135  0.784
2002 Ma D, Jan LY. ER transport signals and trafficking of potassium channels and receptors. Current Opinion in Neurobiology. 12: 287-92. PMID 12049935 DOI: 10.1016/S0959-4388(02)00319-7  0.404
2002 Cohen BE, McAnaney TB, Park ES, Jan YN, Boxer SG, Jan LY. Probing protein electrostatics with a synthetic fluorescent amino acid. Science (New York, N.Y.). 296: 1700-3. PMID 12040199 DOI: 10.1126/Science.1069346  0.7
2002 Ma D, Zerangue N, Raab-Graham K, Fried SR, Jan YN, Jan LY. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron. 33: 715-29. PMID 11879649 DOI: 10.1016/S0896-6273(02)00614-1  0.819
2001 Zou S, Meadows S, Sharp L, Jan LY, Jan YN. Expression Profile of Aging and Oxidative Stress Response in . Thescientificworldjournal. 1: 138. PMID 30147616 DOI: 10.1100/tsw.2001.242  0.572
2001 Hong Y, Stronach B, Perrimon N, Jan LY, Jan YN. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature. 414: 634-8. PMID 11740559 DOI: 10.1038/414634A  0.627
2001 Cooper EC, Harrington E, Jan YN, Jan LY. M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9529-40. PMID 11739564 DOI: 10.1523/Jneurosci.21-24-09529.2001  0.748
2001 Cox DN, Seyfried SA, Jan LY, Jan YN. Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary. Proceedings of the National Academy of Sciences of the United States of America. 98: 14475-80. PMID 11734648 DOI: 10.1073/Pnas.261565198  0.629
2001 Roegiers F, Younger-Shepherd S, Jan LY, Jan YN. Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 98: 14469-74. PMID 11734647 DOI: 10.1073/pnas.261555598  0.623
2001 Margeta-Mitrovic M, Jan YN, Jan LY. Ligand-induced signal transduction within heterodimeric GABA(B) receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 14643-8. PMID 11724957 DOI: 10.1073/pnas.251554798  0.606
2001 Margeta-Mitrovic M, Jan YN, Jan LY. Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors. Proceedings of the National Academy of Sciences of the United States of America. 98: 14649-54. PMID 11724956 DOI: 10.1073/pnas.251554498  0.605
2001 Brenman JE, Gao FB, Jan LY, Jan YN. Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila. Developmental Cell. 1: 667-77. PMID 11709187 DOI: 10.1016/S1534-5807(01)00072-7  0.663
2001 Yi BA, Minor DL, Lin YF, Jan YN, Jan LY. Controlling potassium channel activities: Interplay between the membrane and intracellular factors. Proceedings of the National Academy of Sciences of the United States of America. 98: 11016-23. PMID 11572962 DOI: 10.1073/Pnas.191351798  0.813
2001 Ruan Y, Tecott L, Jiang MM, Jan LY, Jan YN. Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized. Proceedings of the National Academy of Sciences of the United States of America. 98: 9907-12. PMID 11481456 DOI: 10.1073/Pnas.171321098  0.626
2001 Yi BA, Lin YF, Jan YN, Jan LY. Yeast screen for constitutively active mutant G protein-activated potassium channels. Neuron. 29: 657-67. PMID 11301025 DOI: 10.1016/S0896-6273(01)00241-0  0.751
2001 Zerangue N, Malan MJ, Fried SR, Dazin PF, Jan YN, Jan LY, Schwappach B. Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 2431-6. PMID 11226256 DOI: 10.1073/Pnas.051630198  0.78
2001 Lu T, Ting AY, Mainland J, Jan LY, Schultz PG, Yang J. Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter. Nature Neuroscience. 4: 239-46. PMID 11224539 DOI: 10.1038/85080  0.447
2001 Ma D, Zerangue N, Lin YF, Collins A, Yu M, Jan YN, Jan LY. Role of ER export signals in controlling surface potassium channel numbers. Science (New York, N.Y.). 291: 316-9. PMID 11209084 DOI: 10.1126/Science.291.5502.316  0.815
2001 Lu B, Roegiers F, Jan LY, Jan YN. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature. 409: 522-5. PMID 11206549 DOI: 10.1038/35054077  0.628
2001 Roegiers F, Younger-Shepherd S, Jan LY, Jan YN. Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage. Nature Cell Biology. 3: 58-67. PMID 11146627 DOI: 10.1038/35050568  0.624
2000 Zou S, Meadows S, Sharp L, Jan LY, Jan YN. Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 97: 13726-31. PMID 11095759 DOI: 10.1073/pnas.260496697  0.574
2000 Gao FB, Kohwi M, Brenman JE, Jan LY, Jan YN. Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons. Neuron. 28: 91-101. PMID 11086986 DOI: 10.1016/S0896-6273(00)00088-X  0.644
2000 Jan LY, Stevens CF. Signalling mechanisms: a decade of signalling. Current Opinion in Neurobiology. 10: 625-30. PMID 11084325 DOI: 10.1016/S0959-4388(00)00131-8  0.309
2000 Yi BA, Jan LY. Taking apart the gating of voltage-gated K+ channels. Neuron. 27: 423-5. PMID 11055424 DOI: 10.1016/S0896-6273(00)00052-0  0.578
2000 Minor DL, Lin YF, Mobley BC, Avelar A, Jan YN, Jan LY, Berger JM. The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell. 102: 657-70. PMID 11007484 DOI: 10.1016/S0092-8674(00)00088-X  0.736
2000 Jan LY, Jan YN. Heartfelt crosstalk: desensitization of the GIRK current. Nature Cell Biology. 2: E165-7. PMID 10980715 DOI: 10.1038/35023646  0.625
2000 Moore AW, Barbel S, Jan LY, Jan YN. A genomewide survey of basic helix-loop-helix factors in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 97: 10436-41. PMID 10973473 DOI: 10.1073/pnas.170301897  0.617
2000 Margeta-Mitrovic M, Jan YN, Jan LY. A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron. 27: 97-106. PMID 10939334 DOI: 10.1016/S0896-6273(00)00012-X  0.612
2000 Lu B, Jan L, Jan YN. Control of cell divisions in the nervous system: symmetry and asymmetry. Annual Review of Neuroscience. 23: 531-56. PMID 10845074 DOI: 10.1146/Annurev.Neuro.23.1.531  0.613
2000 Zhong W, Jiang MM, Schonemann MD, Meneses JJ, Pedersen RA, Jan LY, Jan YN. Mouse numb is an essential gene involved in cortical neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 6844-9. PMID 10841580 DOI: 10.1073/Pnas.97.12.6844  0.637
2000 Sun Y, Jan LY, Jan YN. Ectopic scute induces Drosophila ommatidia development without R8 founder photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 6815-9. PMID 10823908 DOI: 10.1073/pnas.110154497  0.603
2000 Schwappach B, Zerangue N, Jan YN, Jan LY. Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter. Neuron. 26: 155-67. PMID 10798400 DOI: 10.1016/S0896-6273(00)81146-0  0.803
2000 Cooper EC, Aldape KD, Abosch A, Barbaro NM, Berger MS, Peacock WS, Jan YN, Jan LY. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 97: 4914-9. PMID 10781098 DOI: 10.1073/pnas.090092797  0.752
2000 Zerangue N, Jan YN, Jan LY. An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1. Proceedings of the National Academy of Sciences of the United States of America. 97: 3591-5. PMID 10716722 DOI: 10.1073/Pnas.97.7.3591  0.814
2000 Lin YF, Jan YN, Jan LY. Regulation of ATP-sensitive potassium channel function by protein kinase A-mediated phosphorylation in transfected HEK293 cells. The Embo Journal. 19: 942-55. PMID 10698936 DOI: 10.1093/Emboj/19.5.942  0.681
1999 Lu B, Ackerman L, Jan LY, Jan YN. Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division. Molecular Cell. 4: 883-91. PMID 10635314 DOI: 10.1016/S1097-2765(00)80218-X  0.557
1999 Lu B, Usui T, Uemura T, Jan L, Jan YN. Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila. Current Biology : Cb. 9: 1247-50. PMID 10556092 DOI: 10.1016/S0960-9822(99)80505-3  0.305
1999 Gao FB, Brenman JE, Jan LY, Jan YN. Genes regulating dendritic outgrowth, branching, and routing in Drosophila. Genes & Development. 13: 2549-61. PMID 10521399 DOI: 10.1101/Gad.13.19.2549  0.65
1999 Cooper EC, Jan LY. Ion channel genes and human neurological disease: recent progress, prospects, and challenges. Proceedings of the National Academy of Sciences of the United States of America. 96: 4759-66. PMID 10220366 DOI: 10.1073/pnas.96.9.4759  0.585
1999 Zerangue N, Schwappach B, Jan YN, Jan LY. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. Neuron. 22: 537-48. PMID 10197533 DOI: 10.1016/S0896-6273(00)80708-4  0.819
1999 Minor DL, Masseling SJ, Jan YN, Jan LY. Transmembrane structure of an inwardly rectifying potassium channel. Cell. 96: 879-91. PMID 10102275 DOI: 10.1016/S0092-8674(00)80597-8  0.731
1999 Knoblich JA, Jan LY, Jan YN. Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization. Current Biology : Cb. 9: 155-8. PMID 10021388 DOI: 10.1016/S0960-9822(99)80070-0  0.613
1999 Reuveny E, Jan LY. Chapter 17 G-Protein Control of G-Protein-Gated Potassium Channels Current Topics in Membranes and Transport. 46: 321-335. DOI: 10.1016/S0070-2161(08)60933-8  0.637
1998 Lu B, Rothenberg M, Jan LY, Jan YN. Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors. Cell. 95: 225-35. PMID 9790529 DOI: 10.1016/S0092-8674(00)81753-5  0.614
1998 Chuang HH, Yu M, Jan YN, Jan LY. Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 95: 11727-32. PMID 9751733 DOI: 10.1073/pnas.95.20.11727  0.649
1998 Lu B, Jan LY, Jan YN. Asymmetric cell division: lessons from flies and worms. Current Opinion in Genetics & Development. 8: 392-9. PMID 9729713 DOI: 10.1016/S0959-437X(98)80108-1  0.575
1998 Zeng C, Justice NJ, Abdelilah S, Chan YM, Jan LY, Jan YN. The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development. Proceedings of the National Academy of Sciences of the United States of America. 95: 10637-42. PMID 9724756 DOI: 10.1073/Pnas.95.18.10637  0.608
1998 Jan YN, Jan LY. Serendipity, the principle of limited sloppiness, and neural development. The International Journal of Developmental Biology. 42: 531-3. PMID 9654045 DOI: 10.1387/Ijdb.9654045  0.566
1998 Shen CP, Knoblich JA, Chan YM, Jiang MM, Jan LY, Jan YN. Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila. Genes & Development. 12: 1837-46. PMID 9637685 DOI: 10.1101/Gad.12.12.1837  0.599
1998 Ford CE, Skiba NP, Bae H, Daaka Y, Reuveny E, Shekter LR, Rosal R, Weng G, Yang CS, Iyengar R, Miller RJ, Jan LY, Lefkowitz RJ, Hamm HE. Molecular basis for interactions of G protein betagamma subunits with effectors. Science (New York, N.Y.). 280: 1271-4. PMID 9596582 DOI: 10.1126/Science.280.5367.1271  0.686
1998 Jan YN, Jan LY. Asymmetric cell division. Nature. 392: 775-8. PMID 9572136 DOI: 10.1038/33854  0.601
1998 Zerangue N, Jan LY. G-protein signaling: fine-tuning signaling kinetics. Current Biology : Cb. 8: R313-6. PMID 9560334 DOI: 10.1016/S0960-9822(98)70196-4  0.727
1998 Zeng C, Younger-Shepherd S, Jan LY, Jan YN. Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage. Genes & Development. 12: 1086-91. PMID 9553038 DOI: 10.1101/Gad.12.8.1086  0.608
1998 Cooper EC, Milroy A, Jan YN, Jan LY, Lowenstein DH. Presynaptic localization of Kv1.4-containing A-type potassium channels near excitatory synapses in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 965-74. PMID 9437018 DOI: 10.1523/Jneurosci.18-03-00965.1998  0.728
1998 Stoffel M, Jan LY. Epilepsy genes: excitement traced to potassium channels. Nature Genetics. 18: 6-8. PMID 9425886 DOI: 10.1038/ng0198-6  0.368
1998 Chien CT, Wang S, Rothenberg M, Jan LY, Jan YN. Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo. Molecular and Cellular Biology. 18: 598-607. PMID 9418906 DOI: 10.1128/Mcb.18.1.598  0.617
1997 Li P, Yang X, Wasser M, Cai Y, Chia W, Shen CP, Jan LY, Jan YN. Breaking symmetry in the CNS. Trends in Cell Biology. 7: 422. PMID 17708996 DOI: 10.1016/S0962-8924(97)88137-8  0.512
1997 Knoblich JA, Jan LY, Jan YN. Asymmetric segregation of the Drosophila numb protein during mitosis: facts and speculations. Cold Spring Harbor Symposia On Quantitative Biology. 62: 71-7. PMID 9598338 DOI: 10.1101/Sqb.1997.062.01.011  0.602
1997 Jan LY, Jan YN. Voltage-gated and inwardly rectifying potassium channels. The Journal of Physiology. 505: 267-82. PMID 9423171 DOI: 10.1111/J.1469-7793.1997.267Bb.X  0.437
1997 Vivaudou M, Chan KW, Sui JL, Jan LY, Reuveny E, Logothetis DE. Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants. The Journal of Biological Chemistry. 272: 31553-60. PMID 9395492 DOI: 10.1074/Jbc.272.50.31553  0.716
1997 Jan LY, Jan YN. Ways and means for left shifts in the MaxiK channel. Proceedings of the National Academy of Sciences of the United States of America. 94: 13383-5. PMID 9391031 DOI: 10.1073/PNAS.94.25.13383  0.655
1997 Kanekar S, Perron M, Dorsky R, Harris WA, Jan LY, Jan YN, Vetter ML. Xath5 participates in a network of bHLH genes in the developing Xenopus retina. Neuron. 19: 981-94. PMID 9390513 DOI: 10.1016/S0896-6273(00)80391-8  0.69
1997 Knoblich JA, Jan LY, Jan YN. The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proceedings of the National Academy of Sciences of the United States of America. 94: 13005-10. PMID 9371790 DOI: 10.1073/Pnas.94.24.13005  0.616
1997 Luo L, Lee T, Tsai L, Tang G, Jan LY, Jan YN. Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerization. Proceedings of the National Academy of Sciences of the United States of America. 94: 12963-8. PMID 9371783 DOI: 10.1073/Pnas.94.24.12963  0.614
1997 Slesinger PA, Stoffel M, Jan YN, Jan LY. Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 12210-7. PMID 9342388 DOI: 10.1073/pnas.94.22.12210  0.77
1997 Lüscher C, Jan LY, Stoffel M, Malenka RC, Nicoll RA. G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron. 19: 687-95. PMID 9331358 DOI: 10.1016/S0896-6273(00)80381-5  0.355
1997 Shen CP, Jan LY, Jan YN. Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila. Cell. 90: 449-58. PMID 9267025 DOI: 10.1016/S0092-8674(00)80505-X  0.63
1997 Chuang H, Jan YN, Jan LY. Regulation of IRK3 inward rectifier K+ channel by m1 acetylcholine receptor and intracellular magnesium. Cell. 89: 1121-32. PMID 9215634 DOI: 10.1016/S0092-8674(00)80299-8  0.685
1997 Collins A, Chuang H, Jan YN, Jan LY. Scanning mutagenesis of the putative transmembrane segments of Kir2.1, an inward rectifier potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 94: 5456-60. PMID 9144259 DOI: 10.1073/Pnas.94.10.5456  0.613
1997 Huang CL, Jan YN, Jan LY. Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels. Febs Letters. 405: 291-8. PMID 9108307 DOI: 10.1016/S0014-5793(97)00197-X  0.633
1997 Jan LY, Jan YN. Receptor-regulated ion channels. Current Opinion in Cell Biology. 9: 155-60. PMID 9069261 DOI: 10.1016/S0955-0674(97)80057-9  0.694
1997 Jan LY, Jan YN. Cloned potassium channels from eukaryotes and prokaryotes. Annual Review of Neuroscience. 20: 91-123. PMID 9056709 DOI: 10.1146/annurev.neuro.20.1.91  0.7
1997 Luo L, Jan LY, Jan YN. Rho family GTP-binding proteins in growth cone signalling. Current Opinion in Neurobiology. 7: 81-6. PMID 9039798 DOI: 10.1016/S0959-4388(97)80124-9  0.305
1997 Yang J, Yu M, Jan YN, Jan LY. Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 94: 1568-72. PMID 9037094 DOI: 10.1073/pnas.94.4.1568  0.668
1997 Jan LY, Jan YN. Annual Review Prize Lecture: Voltage-gated and inwardly rectifying potassium channels Journal of Physiology. 505: 267-282. DOI: 10.1111/j.1469-7793.1997.267bb.x  0.66
1996 Tinker A, Jan YN, Jan LY. Regions responsible for the assembly of inwardly rectifying potassium channels. Cell. 87: 857-68. PMID 8945513 DOI: 10.1016/S0092-8674(00)81993-5  0.673
1996 Liao YJ, Jan YN, Jan LY. Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7137-50. PMID 8929423 DOI: 10.1523/Jneurosci.16-22-07137.1996  0.693
1996 Chien CT, Hsiao CD, Jan LY, Jan YN. Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes. Proceedings of the National Academy of Sciences of the United States of America. 93: 13239-44. PMID 8917575 DOI: 10.1073/Pnas.93.23.13239  0.612
1996 Frise E, Knoblich JA, Younger-Shepherd S, Jan LY, Jan YN. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proceedings of the National Academy of Sciences of the United States of America. 93: 11925-32. PMID 8876239 DOI: 10.1073/pnas.93.21.11925  0.627
1996 Kolodziej PA, Timpe LC, Mitchell KJ, Fried SR, Goodman CS, Jan LY, Jan YN. frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance. Cell. 87: 197-204. PMID 8861904 DOI: 10.1016/S0092-8674(00)81338-0  0.616
1996 Jan LY, Jan YN. Membrane permeability. Current Opinion in Cell Biology. 8: 449-51. PMID 8791460 DOI: 10.1016/S0955-0674(96)80019-6  0.53
1996 Slesinger PA, Patil N, Liao YJ, Jan YN, Jan LY, Cox DR. Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels. Neuron. 16: 321-31. PMID 8789947 DOI: 10.1016/S0896-6273(00)80050-1  0.793
1996 Reuveny E, Jan YN, Jan LY. Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation. Biophysical Journal. 70: 754-61. PMID 8789092 DOI: 10.1016/S0006-3495(96)79615-7  0.785
1996 Kraut R, Chia W, Jan LY, Jan YN, Knoblich JA. Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature. 383: 50-5. PMID 8779714 DOI: 10.1038/383050a0  0.623
1996 Zhong W, Feder JN, Jiang MM, Jan LY, Jan YN. Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis. Neuron. 17: 43-53. PMID 8755477 DOI: 10.1016/S0896-6273(00)80279-2  0.619
1996 Guo M, Jan LY, Jan YN. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron. 17: 27-41. PMID 8755476 DOI: 10.1016/S0896-6273(00)80278-0  0.633
1996 Collins A, German MS, Jan YN, Jan LY, Zhao B. A strongly inwardly rectifying K+ channel that is sensitive to ATP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1-9. PMID 8613774 DOI: 10.1523/Jneurosci.16-01-00001.1996  0.682
1996 Doherty D, Feger G, Younger-Shepherd S, Jan LY, Jan YN. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes & Development. 10: 421-34. PMID 8600026 DOI: 10.1101/Gad.10.4.421  0.609
1996 Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, Jan YN. Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines. Nature. 379: 837-40. PMID 8587609 DOI: 10.1038/379837a0  0.632
1996 Fakler B, Schultz JH, Yang J, Schulte U, Brandle U, Zenner HP, Jan LY, Ruppersberg JP. Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH. The Embo Journal. 15: 4093-4099. DOI: 10.1002/J.1460-2075.1996.Tb00784.X  0.459
1995 Yang J, Jan YN, Jan LY. Determination of the subunit stoichiometry of an inwardly rectifying potassium channel. Neuron. 15: 1441-7. PMID 8845166 DOI: 10.1016/0896-6273(95)90021-7  0.687
1995 Jan YN, Jan LY. Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron. 14: 1-5. PMID 7826628 DOI: 10.1016/0896-6273(95)90235-X  0.588
1995 Guo M, Bier E, Jan LY, Jan YN. tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron. 14: 913-25. PMID 7748559 DOI: 10.1016/0896-6273(95)90330-5  0.735
1995 Yang J, Jan YN, Jan LY. Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel. Neuron. 14: 1047-54. PMID 7748552 DOI: 10.1016/0896-6273(95)90343-7  0.681
1995 Kolodziej PA, Jan LY, Jan YN. Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo. Neuron. 15: 273-86. PMID 7646885 DOI: 10.1016/0896-6273(95)90033-0  0.597
1995 Stoffel M, Tokuyama Y, Trabb JB, German MS, Tsaar ML, Jan LY, Polonsky KS, Bell GI. Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochemical and Biophysical Research Communications. 212: 894-9. PMID 7626127 DOI: 10.1006/Bbrc.1995.2053  0.302
1995 Klumpp DJ, Song EJ, Ito S, Sheng MH, Jan LY, Pinto LH. The Shaker-like potassium channels of the mouse rod bipolar cell and their contributions to the membrane current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5004-13. PMID 7623129 DOI: 10.1523/Jneurosci.15-07-05004.1995  0.432
1995 Slesinger PA, Reuveny E, Jan YN, Jan LY. Identification of structural elements involved in G protein gating of the GIRK1 potassium channel. Neuron. 15: 1145-56. PMID 7576657 DOI: 10.1016/0896-6273(95)90102-7  0.797
1995 Huang CL, Slesinger PA, Casey PJ, Jan YN, Jan LY. Evidence that direct binding of G beta gamma to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation. Neuron. 15: 1133-43. PMID 7576656 DOI: 10.1016/0896-6273(95)90101-9  0.755
1995 Sheng M, Jan YN, Jan L. The molecular organization of voltage-dependent K+ channels in vivo. Progress in Brain Research. 105: 87-93. PMID 7568900 DOI: 10.1016/S0079-6123(08)63286-0  0.776
1995 Knoblich JA, Jan LY, Jan YN. Asymmetric segregation of Numb and Prospero during cell division. Nature. 377: 624-7. PMID 7566172 DOI: 10.1038/377624a0  0.583
1995 Xu J, Yu W, Jan YN, Jan LY, Li M. Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits. The Journal of Biological Chemistry. 270: 24761-8. PMID 7559593 DOI: 10.1074/jbc.270.42.24761  0.696
1995 Feger G, Vaessin H, Su TT, Wolff E, Jan LY, Jan YN. dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. The Embo Journal. 14: 5387-98. PMID 7489728 DOI: 10.1002/J.1460-2075.1995.Tb00223.X  0.587
1995 Kubo Y, Reuveny E, Slesinger PA, Baldwin TJ, Jan YN, Jan LY. Primary structure and functional expression of a mouse inward rectifier K+ channel and rat G-protein-coupled muscarinic K+ channel. Japanese Journal of Electrocardiology. 15: 106-113. DOI: 10.5105/Jse.15.106  0.805
1994 Rhyu MS, Jan LY, Jan YN. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell. 76: 477-91. PMID 8313469 DOI: 10.1016/0092-8674(94)90112-0  0.641
1994 Jarman AP, Grell EH, Ackerman L, Jan LY, Jan YN. Atonal is the proneural gene for Drosophila photoreceptors. Nature. 369: 398-400. PMID 8196767 DOI: 10.1038/369398a0  0.606
1994 Ruohola-Baker H, Jan LY, Jan YN. The role of gene cassettes in axis formation during Drosophila oogenesis. Trends in Genetics : Tig. 10: 89-94. PMID 8178370 DOI: 10.1016/0168-9525(94)90231-3  0.626
1994 Jan YN, Jan LY. Neuronal cell fate specification in Drosophila. Current Opinion in Neurobiology. 4: 8-13. PMID 8173329 DOI: 10.1016/0959-4388(94)90025-6  0.638
1994 Sheng M, Tsaur ML, Jan YN, Jan LY. Contrasting subcellular localization of the Kv1.2 K+ channel subunit in different neurons of rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2408-17. PMID 8158277 DOI: 10.1523/Jneurosci.14-04-02408.1994  0.773
1994 Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature. 368: 144-7. PMID 8139656 DOI: 10.1038/368144a0  0.679
1994 Lopez GA, Jan YN, Jan LY. Evidence that the S6 segment of the Shaker voltage-gated K+ channel comprises part of the pore. Nature. 367: 179-82. PMID 8114915 DOI: 10.1038/367179a0  0.679
1994 Liu H, Wang H, Sheng M, Jan LY, Jan YN, Basbaum AI. Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn. Proceedings of the National Academy of Sciences of the United States of America. 91: 8383-7. PMID 8078891 DOI: 10.1073/Pnas.91.18.8383  0.675
1994 Jan LY, Jan YN. Potassium channels and their evolving gates. Nature. 371: 119-22. PMID 8072541 DOI: 10.1038/371119a0  0.681
1994 Giniger E, Tietje K, Jan LY, Jan YN. lola encodes a putative transcription factor required for axon growth and guidance in Drosophila. Development (Cambridge, England). 120: 1385-98. PMID 8050351  0.638
1994 Reuveny E, Slesinger PA, Inglese J, Morales JM, Iñiguez-Lluhi JA, Lefkowitz RJ, Bourne HR, Jan YN, Jan LY. Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature. 370: 143-6. PMID 8022483 DOI: 10.1038/370143A0  0.799
1994 Feder JN, Li L, Jan LY, Jan YN. Genomic cloning and chromosomal localization of HRY, the human homolog to the Drosophila segmentation gene, hairy. Genomics. 20: 56-61. PMID 8020957 DOI: 10.1006/geno.1994.1126  0.605
1994 Jongens TA, Ackerman LD, Swedlow JR, Jan LY, Jan YN. Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila. Genes & Development. 8: 2123-36. PMID 7958883 DOI: 10.1101/Gad.8.18.2123  0.619
1994 Luo L, Liao YJ, Jan LY, Jan YN. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes & Development. 8: 1787-802. PMID 7958857 DOI: 10.1101/Gad.8.15.1787  0.657
1994 Li M, Unwin N, Stauffer KA, Jan YN, Jan LY. Images of purified Shaker potassium channels. Current Biology : Cb. 4: 110-5. PMID 7953509 DOI: 10.1016/S0960-9822(94)00026-6  0.436
1994 Clark I, Giniger E, Ruohola-Baker H, Jan LY, Jan YN. Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte. Current Biology : Cb. 4: 289-300. PMID 7922338 DOI: 10.1016/S0960-9822(00)00068-3  0.743
1994 Jan YN, Jan LY. Genetic control of cell fate specification in Drosophila peripheral nervous system. Annual Review of Genetics. 28: 373-93. PMID 7893132 DOI: 10.1146/annurev.ge.28.120194.002105  0.641
1993 Bodmer R, Jan LY, Jan YN. A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 202: 371-381. PMID 28306050 DOI: 10.1007/BF00188736  0.697
1993 Giniger E, Wells W, Jan LY, Jan YN. Tracing neurons with a kinesin-β-galactosidase fusion protein. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 202: 112-122. PMID 28305652 DOI: 10.1007/BF00636536  0.754
1993 Li M, Isacoff E, Jan YN, Jan LY. Assembly of potassium channels. Annals of the New York Academy of Sciences. 707: 51-9. PMID 9137541 DOI: 10.1111/j.1749-6632.1993.tb38041.x  0.748
1993 Boulianne GL, de la Concha A, Campos-Ortega JA, Jan LY, Jan YN. The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. The Embo Journal. 12: 2586. PMID 8508781 DOI: 10.1002/J.1460-2075.1993.Tb05914.X  0.642
1993 Ruohola-Baker H, Grell E, Chou TB, Baker D, Jan LY, Jan YN. Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis. Cell. 73: 953-65. PMID 8500182 DOI: 10.1016/0092-8674(93)90273-S  0.619
1993 Ghysen A, Dambly-Chaudière C, Jan LY, Jan YN. Cell interactions and gene interactions in peripheral neurogenesis. Genes & Development. 7: 723-33. PMID 8491375 DOI: 10.1101/Gad.7.5.723  0.714
1993 Crowley TE, Hoey T, Liu JK, Jan YN, Jan LY, Tjian R. A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila. Nature. 361: 557-61. PMID 8429912 DOI: 10.1038/361557A0  0.602
1993 Feder JN, Jan LY, Jan YN. A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Molecular and Cellular Biology. 13: 105-13. PMID 8417318 DOI: 10.1128/Mcb.13.1.105  0.599
1993 Slesinger PA, Jan YN, Jan LY. The S4-S5 loop contributes to the ion-selective pore of potassium channels. Neuron. 11: 739-49. PMID 8398157 DOI: 10.1016/0896-6273(93)90083-4  0.764
1993 Isacoff EY, Jan YN, Jan LY. Molecular basis of K+ channel inactivation gating. Exs. 63: 338-51. PMID 8380732 DOI: 10.1007/978-3-0348-7265-2_18  0.749
1993 Jan YN, Jan LY. Functional gene cassettes in development. Proceedings of the National Academy of Sciences of the United States of America. 90: 8305-7. PMID 8378299 DOI: 10.1073/Pnas.90.18.8305  0.597
1993 Sheng M, Liao YJ, Jan YN, Jan LY. Presynaptic A-current based on heteromultimeric K+ channels detected in vivo. Nature. 365: 72-5. PMID 8361540 DOI: 10.1038/365072a0  0.76
1993 Kubo Y, Reuveny E, Slesinger PA, Jan YN, Jan LY. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature. 364: 802-6. PMID 8355805 DOI: 10.1038/364802A0  0.817
1993 Giniger E, Jan LY, Jan YN. Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch. Development (Cambridge, England). 117: 431-40. PMID 8330518  0.614
1993 Jarman AP, Grau Y, Jan LY, Jan YN. atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell. 73: 1307-21. PMID 8324823 DOI: 10.1016/0092-8674(93)90358-W  0.611
1993 Jan YN, Jan LY. HLH proteins, fly neurogenesis, and vertebrate myogenesis. Cell. 75: 827-30. PMID 8252617 DOI: 10.1016/0092-8674(93)90525-U  0.607
1993 Kubo Y, Baldwin TJ, Jan YN, Jan LY. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 362: 127-33. PMID 7680768 DOI: 10.1038/362127a0  0.68
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1993 Giniger E, Wells W, Jan LY, Jan YN. Tracing neurons with a kinesin-β-galactosidase fusion protein Roux's Archives of Developmental Biology. 202: 112-122. DOI: 10.1007/BF00636536  0.736
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1992 Tsaur ML, Sheng M, Lowenstein DH, Jan YN, Jan LY. Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures. Neuron. 8: 1055-67. PMID 1610565 DOI: 10.1016/0896-6273(92)90127-Y  0.759
1992 Jan LY, Jan YN. Structural elements involved in specific K+ channel functions. Annual Review of Physiology. 54: 537-55. PMID 1562183 DOI: 10.1146/annurev.ph.54.030192.002541  0.699
1992 Younger-Shepherd S, Vaessin H, Bier E, Jan LY, Jan YN. deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell. 70: 911-22. PMID 1525829 DOI: 10.1016/0092-8674(92)90242-5  0.703
1992 Li M, Jan YN, Jan LY. Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel. Science (New York, N.Y.). 257: 1225-30. PMID 1519059 DOI: 10.1126/Science.1519059  0.686
1992 Sheng M, Tsaur ML, Jan YN, Jan LY. Subcellular segregation of two A-type K+ channel proteins in rat central neurons. Neuron. 9: 271-84. PMID 1497894 DOI: 10.1016/0896-6273(92)90166-B  0.773
1992 Rao Y, Bodmer R, Jan LY, Jan YN. The big brain gene of Drosophila functions to control the number of neuronal precursors in the peripheral nervous system. Development (Cambridge, England). 116: 31-40. PMID 1483394  0.524
1992 Bier E, Vaessin H, Younger-Shepherd S, Jan LY, Jan YN. deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product. Genes & Development. 6: 2137-51. PMID 1427077 DOI: 10.1101/GAD.6.11.2137  0.729
1992 Jongens TA, Hay B, Jan LY, Jan YN. The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila. Cell. 70: 569-84. PMID 1380406 DOI: 10.1016/0092-8674(92)90427-E  0.618
1992 Jan LY, Jan YN. Tracing the roots of ion channels. Cell. 69: 715-8. PMID 1375539 DOI: 10.1016/0092-8674(92)90280-P  0.692
1992 Baldwin TJ, Isacoff E, Li M, Lopez GA, Sheng M, Tsaur ML, Yan YN, Jan LY. Elucidation of biophysical and biological properties of voltage-gated potassium channels. Cold Spring Harbor Symposia On Quantitative Biology. 57: 491-9. PMID 1339685 DOI: 10.1101/Sqb.1992.057.01.054  0.614
1991 Ruohola H, Bremer KA, Baker D, Swedlow JR, Jan LY, Jan YN. Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila. Cell. 66: 433-49. PMID 1907889 DOI: 10.1016/0092-8674(81)90008-8  0.625
1991 Rao Y, Vaessin H, Jan LY, Jan YN. Neuroectoderm in Drosophila embryos is dependent on the mesoderm for positioning but not for formation. Genes & Development. 5: 1577-88. PMID 1885000 DOI: 10.1101/Gad.5.9.1577  0.715
1991 Isacoff EY, Jan YN, Jan LY. Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel. Nature. 353: 86-90. PMID 1881453 DOI: 10.1038/353086a0  0.759
1991 Papazian DM, Timpe LC, Jan YN, Jan LY. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature. 349: 305-10. PMID 1846229 DOI: 10.1038/349305a0  0.661
1991 Baldwin TJ, Tsaur ML, Lopez GA, Jan YN, Jan LY. Characterization of a mammalian cDNA for an inactivating voltage-sensitive K+ channel. Neuron. 7: 471-83. PMID 1840649 DOI: 10.1016/0896-6273(91)90299-F  0.673
1991 Vaessin H, Grell E, Wolff E, Bier E, Jan LY, Jan YN. prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell. 67: 941-53. PMID 1720353 DOI: 10.1016/0092-8674(91)90367-8  0.737
1991 Blochlinger K, Jan LY, Jan YN. Transformation of sensory organ identity by ectopic expression of Cut in Drosophila Genes and Development. 5: 1124-1135. PMID 1676691 DOI: 10.1101/Gad.5.7.1124  0.607
1990 Schwarz TL, Papazian DM, Carretto RC, Jan YN, Jan LY. Immunological characterization of K+ channel components from the Shaker locus and differential distribution of splicing variants in Drosophila. Neuron. 4: 119-27. PMID 2310570 DOI: 10.1016/0896-6273(90)90448-O  0.438
1990 Klaiber K, Williams N, Roberts TM, Papazian DM, Jan LY, Miller C. Functional expression of Shaker K+ channels in a baculovirus-infected insect cell line. Neuron. 5: 221-6. PMID 2200450 DOI: 10.1016/0896-6273(90)90311-3  0.374
1990 Isacoff E, Papazian D, Timpe L, Jan YN, Jan LY. Molecular studies of voltage-gated potassium channels. Cold Spring Harbor Symposia On Quantitative Biology. 55: 9-17. PMID 2132867 DOI: 10.1101/Sqb.1990.055.01.004  0.751
1990 Vaessin H, Caudy M, Bier E, Jan LY, Jan YN. Role of helix-loop-helix proteins in Drosophila neurogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 55: 239-45. PMID 2132818 DOI: 10.1101/SQB.1990.055.01.026  0.689
1990 Isacoff EY, Jan YN, Jan LY. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature. 345: 530-4. PMID 2112229 DOI: 10.1038/345530a0  0.764
1990 Bier E, Jan LY, Jan YN. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes & Development. 4: 190-203. PMID 2110920 DOI: 10.1101/Gad.4.2.190  0.726
1990 Blochlinger K, Bodmer R, Jan LY, Jan YN. Patterns of expression of Cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos Genes and Development. 4: 1322-1331. PMID 1977661 DOI: 10.1101/Gad.4.8.1322  0.71
1990 Jan YN, Jan LY. Genes required for specifying cell fates in Drosophila embryonic sensory nervous system Trends in Neurosciences. 13: 493-498. PMID 1703680 DOI: 10.1016/0166-2236(90)90083-M  0.655
1990 Jan LY, Jan YN. How might the diversity of potassium channels be generated? Trends in Neurosciences. 13: 415-419. PMID 1700515 DOI: 10.1016/0166-2236(90)90123-R  0.695
1990 Jan LY, Jan YN. A superfamily of ion channels [14] Nature. 345: 672. PMID 1694264 DOI: 10.1038/345672A0  0.657
1990 Rao Y, Jan LY, Jan YN. Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins. Nature. 345: 163-7. PMID 1692392 DOI: 10.1038/345163a0  0.601
1989 Uemura T, Shepherd S, Ackerman L, Jan LY, Jan YN. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos Cell. 58: 349-360. PMID 2752427 DOI: 10.1016/0092-8674(89)90849-0  0.638
1989 Jan LY, Jan YN. Voltage-sensitive ion channels Cell. 56: 13-25. PMID 2463091 DOI: 10.1016/0092-8674(89)90979-3  0.658
1988 Dambly-Chaudière C, Ghysen A, Jan LY, Jan YN. The determination of sense organs in Drosophila: interaction of scute with daughterless. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 197: 419-423. PMID 28305749 DOI: 10.1007/BF00398993  0.692
1988 Timpe LC, Jan YN, Jan LY. Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes Neuron. 1: 659-667. PMID 3272184 DOI: 10.1016/0896-6273(88)90165-1  0.659
1988 Caudy M, Grell EH, Dambly-Chaudière C, Ghysen A, Jan LY, Jan YN. The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila. Genes & Development. 2: 843-52. PMID 3209070 DOI: 10.1101/GAD.2.7.843  0.73
1988 Bier E, Ackerman L, Barbel S, Jan L, Jan YN. Identification and characterization of a neuron-specific nuclear antigen in Drosophila. Science (New York, N.Y.). 240: 913-6. PMID 3129785 DOI: 10.1126/SCIENCE.3129785  0.721
1988 Hay B, Jan LY, Jan YN. A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases Cell. 55: 577-587. PMID 3052853 DOI: 10.1016/0092-8674(88)90216-4  0.606
1988 Blochlinger K, Bodmer R, Jack J, Jan LY, Jan YN. Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila. Nature. 333: 629-35. PMID 2897632 DOI: 10.1038/333629a0  0.694
1988 Papazian DM, Schwarz TL, Tempel BL, Timpe LC, Jan LY. Ion channels in Drosophila. Annual Review of Physiology. 50: 379-94. PMID 2454072 DOI: 10.1146/annurev.ph.50.030188.002115  0.665
1988 Tempel BL, Jan YN, Jan LY. Cloning of a probable potassium channel gene from mouse brain. Nature. 332: 837-9. PMID 2451788 DOI: 10.1038/332837a0  0.795
1988 Timpe LC, Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY. Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes. Nature. 331: 143-5. PMID 2448636 DOI: 10.1038/331143a0  0.805
1988 Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY. Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature. 331: 137-42. PMID 2448635 DOI: 10.1038/331137a0  0.804
1988 Dambly-Chaudière C, Ghysen A, Jan LY, Jan YN. The determination of sense organs in Drosophila: interaction of scute with daughterless Roux's Archives of Developmental Biology. 197: 419-423. DOI: 10.1007/BF00398993  0.673
1987 Bodmer R, Barbel S, Sheperd S, Jack JW, Jan LY, Jan YN. Transformation of sensory organs by mutations of the cut locus of D. melanogaster. Cell. 51: 293-307. PMID 3117374 DOI: 10.1016/0092-8674(87)90156-5  0.688
1987 Bowers CW, Phillips HS, Lee P, Jan YN, Jan LY. Identification and purification of an irreversible presynaptic neurotoxin from the venom of the spider Hololena curta. Proceedings of the National Academy of Sciences of the United States of America. 84: 3506-10. PMID 3033650 DOI: 10.1073/PNAS.84.10.3506  0.659
1987 Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science (New York, N.Y.). 237: 770-5. PMID 2441471 DOI: 10.1126/Science.2441471  0.81
1987 Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science (New York, N.Y.). 237: 749-53. PMID 2441470 DOI: 10.1126/Science.2441470  0.8
1986 Dambly-Chaudière C, Ghysen A, Jan YN, Jan LY. Muscle connections between imaginal discs in Drosophila. Developmental Biology. 113: 288-94. PMID 3081389 DOI: 10.1016/0012-1606(86)90164-8  0.704
1986 Bowers CW, Jan LY, Jan YN. A substance P-like peptide in bullfrog autonomic nerve terminals: Anatomy biochemistry and physiology Neuroscience. 19: 343-356. PMID 2431351 DOI: 10.1016/0306-4522(86)90026-6  0.621
1985 Ghysen A, Jan LY, Jan YN. Segmental determination in Drosophila central nervous system. Cell. 40: 943-8. PMID 3886161 DOI: 10.1016/0092-8674(85)90354-X  0.529
1985 Jan Y, Ghysen A, Christoph I, Barbel S, Jan L. Formation of neuronal pathways in the imaginal discs of Drosophila melanogaster The Journal of Neuroscience. 5: 2453-2464. DOI: 10.1523/JNEUROSCI.05-09-02453.1985  0.712
1985 Jan LY, Barbel S, Timpe L, Laffer C, Salkoff L, O'Farrell P, Jan YN. Chapter 4 Studies of Shaker Mutations Affecting a K+ Channel in Drosophila Current Topics in Membranes and Transport. 23: 67-77. DOI: 10.1016/S0070-2161(08)60150-1  0.784
1985 Jan LY, Papazian DM, Timpe L, O'Farrell P, Jan YN. Application of drosophila molecular genetics in the study of neural function - studies of the shaker locus for a potassium channel Trends in Neurosciences. 8: 234-238. DOI: 10.1016/0166-2236(85)90095-5  0.639
1983 Jan YN, Bowers CW, Branton D, Evans L, Jan LY. Peptides in neuronal function: studies using frog autonomic ganglia. Cold Spring Harbor Symposia On Quantitative Biology. 48: 363-74. PMID 6327165 DOI: 10.1101/SQB.1983.048.01.040  0.603
1983 Jan LY, Barbel S, Timpe L, Laffer C, Salkoff L, O'Farrell P, Jan YN. Mutating a gene for a potassium channel by hybrid dysgenesis: an approach to the cloning of the Shaker locus in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 48: 233-45. PMID 6327158 DOI: 10.1101/Sqb.1983.048.01.026  0.76
1983 Jan YN, Jan LY. Some Features of Peptidergic Transmission Progress in Brain Research. 58: 49-59. PMID 6138814 DOI: 10.1016/S0079-6123(08)60006-0  0.605
1983 Jan YN, Jan LY. A LHRH-like peptidergic neurotransmitter capable of 'action at a distance' in autonomic ganglia Trends in Neurosciences. 6: 320-325. DOI: 10.1016/0166-2236(83)90148-0  0.588
1982 Jan LY, Jan YN. Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos Proceedings of the National Academy of Sciences of the United States of America. 79: 2700-2704. PMID 6806816 DOI: 10.1073/Pnas.79.8.2700  0.615
1982 Jan LY, Jan YN. Peptidergic transmission in sympathetic ganglia of the frog The Journal of Physiology. 327: 219-246. PMID 6181250 DOI: 10.1113/jphysiol.1982.sp014228  0.589
1982 Ghysen A, Dambly-Chaudière C, Jan L, Jan Y. Segmental differences in the protein content of Drosophila imaginal discs The Embo Journal. 1: 1373-1379. DOI: 10.1002/j.1460-2075.1982.tb01325.x  0.716
1980 Jan YN, Jan LY, Kuffler SW. Further evidence for peptidergic transmission in sympathetic ganglia. Proceedings of the National Academy of Sciences of the United States of America. 77: 5008-12. PMID 6254052 DOI: 10.1073/Pnas.77.8.5008  0.725
1980 Jan LY, Jan YN, Brownfield MS. Peptidergic transmitters in synaptic boutons of sympathetic ganglia Nature. 288: 380-382. PMID 6107864 DOI: 10.1038/288380a0  0.607
1979 Jan YN, Jan LY, Kuffler SW. A peptide as a possible transmitter in sympathetic ganglia of the frog. Proceedings of the National Academy of Sciences of the United States of America. 76: 1501-5. PMID 35789 DOI: 10.1073/Pnas.76.3.1501  0.726
1978 Wu CF, Ganetzky B, Jan LY, Jan YN, Benzer S. A Drosophila mutant with a temperature-sensitive block in nerve conduction. Proceedings of the National Academy of Sciences of the United States of America. 75: 4047-51. PMID 211514 DOI: 10.1073/Pnas.75.8.4047  0.773
1978 Jan YN, Jan LY. Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction Proceedings of the National Academy of Sciences of the United States of America. 75: 515-519. PMID 24218 DOI: 10.1073/Pnas.75.1.515  0.576
1977 Jan YN, Jan LY, Dennis MJ. Two mutations of synaptic transmission in Drosophila. Proceedings of the Royal Society of London. Series B, Biological Sciences. 198: 87-108. PMID 20636 DOI: 10.1098/rspb.1977.0087  0.646
1976 Jan LY, Jan YN. L‐glutamate as an excitatory transmitter at the Drosophila larval neuromuscular junction The Journal of Physiology. 262: 215-236. PMID 186587 DOI: 10.1113/jphysiol.1976.sp011593  0.598
1976 Jan LY, Jan YN. Properties of the larval neuromuscular junction in Drosophila melanogaster The Journal of Physiology. 262: 189-214. PMID 11339 DOI: 10.1113/jphysiol.1976.sp011592  0.588
1975 Jan LY, Revel JP. Hemocyanin - antibody labeling of phodopsin in mouse retina for a scanning electron microscope study. Journal of Supramolecular Structure. 3: 61-6. PMID 1152468 DOI: 10.1002/jss.400030107  0.526
1974 Jan LY, Revel JP. Ultrastructural localization of rhodopsin in the vertebrate retina. The Journal of Cell Biology. 62: 257-73. PMID 4139160 DOI: 10.1083/Jcb.62.2.257  0.526
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