Year |
Citation |
Score |
2009 |
Cenedella RJ. Cholesterol synthesis inhibitor U18666A and the role of sterol metabolism and trafficking in numerous pathophysiological processes. Lipids. 44: 477-87. PMID 19440746 DOI: 10.1007/S11745-009-3305-7 |
0.413 |
|
2009 |
Dowling S, Cox J, Cenedella RJ. Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo. Lipids. 44: 489-98. PMID 19381703 DOI: 10.1007/S11745-009-3298-2 |
0.313 |
|
2007 |
Cenedella RJ, Sexton PS, Brako L, Lo WK, Jacob RF. Status of caveolin-1 in various membrane domains of the bovine lens. Experimental Eye Research. 85: 473-81. PMID 17669400 DOI: 10.1016/J.Exer.2007.05.011 |
0.377 |
|
2005 |
Cenedella RJ, Sexton PS, Krishnan K, Covey DF. Comparison of effects of U18666A and enantiomeric U18666A on sterol synthesis and induction of apoptosis. Lipids. 40: 635-40. PMID 16149744 DOI: 10.1007/S11745-005-1426-9 |
0.354 |
|
2005 |
Cenedella RJ, Neely AR, Sexton P. Concentration and distribution of ubiquinone (coenzyme Q), the endogenous lipid antioxidant, in the rat lens: effect of treatment with simvastatin. Molecular Vision. 11: 594-602. PMID 16110301 |
0.331 |
|
2004 |
Cenedella RJ, Jacob R, Borchman D, Tang D, Neely AR, Samadi A, Mason RP, Sexton P. Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor. Journal of Lipid Research. 45: 1232-41. PMID 15102886 DOI: 10.1194/Jlr.M300469-Jlr200 |
0.404 |
|
2004 |
Sexton PS, Neely AR, Cenedella RJ. Distribution of caveolin-1 in bovine lens and redistribution in cultured bovine lens epithelial cells upon confluence. Experimental Eye Research. 78: 75-82. PMID 14667829 DOI: 10.1016/J.Exer.2003.09.022 |
0.337 |
|
2003 |
Cenedella RJ, Kuszak JR, Al-Ghoul KJ, Qin S, Sexton PS. Discordant expression of the sterol pathway in lens underlies simvastatin-induced cataracts in Chbb: Thom rats. Journal of Lipid Research. 44: 198-211. PMID 12518039 DOI: 10.1194/Jlr.M200002-Jlr200 |
0.364 |
|
2002 |
Sexton PS, Cenedella RJ. Immunomagnetic capture of lens membrane fractions containing steroid binding protein. Biochemical and Biophysical Research Communications. 295: 1027-31. PMID 12127999 DOI: 10.1016/S0006-291X(02)00770-2 |
0.338 |
|
2001 |
Cenedella RJ. Specific labeling of lens aldehyde dehydrogenase class 1 from (3)H-cholesterol or its derivatives. Ophthalmic Research. 33: 210-6. PMID 11464073 DOI: 10.1159/000055672 |
0.354 |
|
2001 |
Zhu XL, Sexton PS, Cenedella RJ. Characterization of membrane steroid binding protein mRNA and protein in lens epithelial cells. Experimental Eye Research. 73: 213-9. PMID 11446771 DOI: 10.1006/Exer.2001.1032 |
0.313 |
|
2001 |
Jacob RF, Cenedella RJ, Mason RP. Evidence for distinct cholesterol domains in fiber cell membranes from cataractous human lenses. The Journal of Biological Chemistry. 276: 13573-8. PMID 11278611 DOI: 10.1074/Jbc.M010077200 |
0.4 |
|
2000 |
Fliesler SJ, Richards MJ, Miller C, Peachey NS, Cenedella RJ. Retinal structure and function in an animal model that replicates the biochemical hallmarks of desmosterolosis. Neurochemical Research. 25: 685-94. PMID 10905631 DOI: 10.1023/A:1007519321917 |
0.362 |
|
2000 |
Fliesler SJ, Richards MJ, Miller CY, Cenedella RJ. Cholesterol synthesis in the vertebrate retina: effects of U18666A on rat retinal structure, photoreceptor membrane assembly, and sterol metabolism and composition. Lipids. 35: 289-96. PMID 10783006 DOI: 10.1007/S11745-000-0525-Y |
0.393 |
|
1999 |
Mitchell J, Cenedella RJ. Human lens cholesterol concentrations in patients who used lovastatin or simvastatin. Archives of Ophthalmology (Chicago, Ill. : 1960). 117: 653-7. PMID 10326964 DOI: 10.1001/Archopht.117.5.653 |
0.406 |
|
1999 |
Cenedella RJ, Chandrasekher G. Intense myristoylation of a single protein in the ocular lens. Biochemical and Biophysical Research Communications. 256: 652-6. PMID 10080954 DOI: 10.1006/Bbrc.1999.0399 |
0.342 |
|
1998 |
Tang D, Borchman D, Yappert MC, Cenedella RJ. Influence of cholesterol on the interaction of alpha-crystallin with phospholipids. Experimental Eye Research. 66: 559-67. PMID 9628803 DOI: 10.1006/Exer.1997.0467 |
0.354 |
|
1998 |
Cenedella RJ, Sexton PS. Probing cataractogenesis associated with mevalonic aciduria. Current Eye Research. 17: 153-8. PMID 9523093 DOI: 10.1076/Ceyr.17.2.153.5599 |
0.383 |
|
1997 |
Cenedella RJ. Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols. Experimental Eye Research. 65: 63-72. PMID 9237866 DOI: 10.1006/Exer.1997.0310 |
0.373 |
|
1997 |
Chandrasekher G, Cenedella RJ. Properties of alpha-crystallin bound to lens membrane: probing organization at the membrane surface. Experimental Eye Research. 64: 423-30. PMID 9196394 DOI: 10.1006/Exer.1996.0228 |
0.332 |
|
1997 |
Fleschner CR, Cenedella RJ. Neutral lipids of the plasma membrane: composition of plasma membrane fractions isolated from ocular lens. Current Eye Research. 16: 263-9. PMID 9088744 DOI: 10.1076/Ceyr.16.3.263.15402 |
0.371 |
|
1996 |
Borchman D, Cenedella RJ, Lamba OP. Role of cholesterol in the structural order of lens membrane lipids. Experimental Eye Research. 62: 191-7. PMID 8698079 DOI: 10.1006/Exer.1996.0023 |
0.414 |
|
1996 |
Cenedella RJ. Cholesterol and cataracts. Survey of Ophthalmology. 40: 320-37. PMID 8658343 DOI: 10.1016/S0039-6257(96)82007-8 |
0.432 |
|
1995 |
Chandrasekher G, Cenedella RJ. Protein associated with human lens 'native' membrane during aging and cataract formation. Experimental Eye Research. 60: 707-17. PMID 7641853 DOI: 10.1016/S0014-4835(05)80012-0 |
0.368 |
|
1995 |
Mitchell J, Cenedella RJ. Quantitation of ultraviolet light-absorbing fractions of the cornea. Cornea. 14: 266-72. PMID 7600810 DOI: 10.1097/00003226-199505000-00007 |
0.303 |
|
1993 |
Fleschner CR, Cenedella RJ. Isolation of a non-sedimenting membrane fraction from the water soluble fraction of bovine lens. Experimental Eye Research. 56: 649-57. PMID 8595807 DOI: 10.1006/Exer.1993.1082 |
0.395 |
|
1993 |
Cenedella RJ, Mitchell J. Antagonism of [3H]fatty acid incorporation into vimentin by sodium pyruvate: pitfalls of protein acylation. Lipids. 28: 235-40. PMID 8464354 DOI: 10.1007/Bf02536645 |
0.319 |
|
1993 |
Cenedella RJ, Chandrasekher G. High capacity binding of alpha crystallins to various bovine lens membrane preparations. Current Eye Research. 12: 1025-38. PMID 8306713 DOI: 10.3109/02713689309029230 |
0.334 |
|
1993 |
Chandrasekher G, Cenedella RJ. Calcium activated proteolysis and protein modification in the U18666A cataract. Experimental Eye Research. 57: 737-45. PMID 8150025 DOI: 10.1006/Exer.1993.1181 |
0.329 |
|
1993 |
Willingham AK, Bolanos C, Bohannan E, Cenedella RJ. The effects of high levels of vitamin E on the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit The Journal of Nutritional Biochemistry. 4: 651-654. DOI: 10.1016/0955-2863(93)90038-X |
0.35 |
|
1992 |
Cenedella RJ, Linton LL, Moore CP. Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. Biochemical and Biophysical Research Communications. 186: 1647-55. PMID 1510688 DOI: 10.1016/S0006-291X(05)81597-9 |
0.37 |
|
1992 |
Cenedella RJ, Fleschner CR. Selective association of crystallins with lens 'native' membrane during dynamic cataractogenesis. Current Eye Research. 11: 801-15. PMID 1424724 DOI: 10.3109/02713689209000753 |
0.377 |
|
1992 |
Fleschner CR, Cenedella RJ. Examination of a lens 'native' plasma membrane fraction and its associated crystallins. Current Eye Research. 11: 739-52. PMID 1424720 DOI: 10.3109/02713689209000748 |
0.368 |
|
1988 |
Fleschner CR, Cenedella RJ. Specific restriction of cholesterol from cortical lens gap junctional membrane in the U18666A cataract. Current Eye Research. 7: 1029-34. PMID 3229122 DOI: 10.3109/02713688809015150 |
0.405 |
|
1987 |
el-Sayed GN, Cenedella RJ. Relationship of cholesterolgenesis to DNA synthesis and proliferation by lens epithelial cells in culture. Experimental Eye Research. 45: 443-51. PMID 3666066 DOI: 10.1016/S0014-4835(87)80129-X |
0.31 |
|
1987 |
Cenedella RJ. Inhibitors of cholesterol synthesis and cataracts. Jama. 257: 1602. PMID 3644022 DOI: 10.1001/Jama.1987.03390120064020 |
0.392 |
|
1987 |
Cenedella RJ. Direct chemical measurement of DNA synthesis and net rates of differentiation of rat lens epithelial cells in vivo: applied to the selenium cataract. Experimental Eye Research. 44: 677-90. PMID 3622647 DOI: 10.1016/S0014-4835(87)80138-0 |
0.308 |
|
1987 |
Rintoul DA, Cundy KV, Cenedella RJ. Physical properties of membranes and membrane lipids from the fiber cell of the U18666A-cataractous rat. Current Eye Research. 6: 1343-8. PMID 3427983 DOI: 10.3109/02713688708997560 |
0.395 |
|
1985 |
Cenedella RJ. Regional distribution of lipids and phospholipase A2 activity in normal and cataractous rat lens. Current Eye Research. 4: 113-20. PMID 3987344 DOI: 10.3109/02713688508999976 |
0.379 |
|
1985 |
Alcala J, Cenedella RJ, Katar M. Limited proteolysis of MP26 in lens fiber plasma membranes of the U18666A-induced cataract in rats. Current Eye Research. 4: 1001-5. PMID 3905265 DOI: 10.3109/02713689509000008 |
0.331 |
|
1984 |
Cenedella RJ, Sarkar CP. Mechanism of depression of brain phospholipid levels by an epileptogenic drug. Biochemical Pharmacology. 33: 591-8. PMID 6704175 DOI: 10.1016/0006-2952(84)90313-7 |
0.416 |
|
1984 |
Cenedella RJ. Lipoproteins and lipids in cow and human aqueous humor. Biochimica Et Biophysica Acta. 793: 448-54. PMID 6424721 DOI: 10.1016/0005-2760(84)90262-5 |
0.388 |
|
1983 |
Cenedella RJ. Source of cholesterol for the ocular lens, studied with U18666A: a cataract-producing inhibitor of lipid metabolism. Experimental Eye Research. 37: 33-43. PMID 6873203 DOI: 10.1016/0014-4835(83)90147-1 |
0.465 |
|
1982 |
Sarkar CP, Cenedella RJ. Gangliosides in normal and cataractous lenses of several species. Biochimica Et Biophysica Acta. 711: 503-8. PMID 7104379 DOI: 10.1016/0005-2760(82)90065-0 |
0.373 |
|
1982 |
Cenedella RJ, Sarkar CP, Towns L. Studies on the mechanism of the epileptiform activity induced by U18666A. II. Concentration, half-life and distribution of radiolabeled U18666A in the brain. Epilepsia. 23: 257-68. PMID 7084137 DOI: 10.1111/J.1528-1157.1982.Tb06190.X |
0.405 |
|
1982 |
Sarkar CP, Bierkamper GG, Cenedella RJ. Studies on the mechanisms of the epileptiform activity induced by U186661. I Gross alteration of the lipids of synaptosomes and myelin. Epilepsia. 23: 243-55. PMID 7084136 DOI: 10.1111/J.1528-1157.1982.Tb06189.X |
0.715 |
|
1982 |
Cenedella RJ. Digitonide precipitable sterols: a reevaluation with special attention to lanosterol. Lipids. 17: 443-7. PMID 7050581 DOI: 10.1007/Bf02535224 |
0.352 |
|
1982 |
Sarkar CP, Cenedella RJ. Reactivity of key metabolic sterols in standard colorimetric assays for cholesterol. Lipids. 17: 46-9. PMID 6177997 DOI: 10.1007/Bf02535121 |
0.348 |
|
1980 |
Cenedella RJ. Concentration-dependent effects of AY-9944 and U18666A on sterol synthesis in brain. Variable sensitivities of metabolic steps. Biochemical Pharmacology. 29: 2751-4. PMID 6159896 DOI: 10.1016/0006-2952(80)90006-4 |
0.367 |
|
1979 |
Cenedella RJ. Composition and synthesis in vivo of water-soluble proteins in the rat ocular lens: normal and cataractous. Experimental Eye Research. 29: 655-62. PMID 544282 DOI: 10.1016/0014-4835(79)90021-6 |
0.346 |
|
1979 |
Cenedella RJ, Bierkamper GG. Mechanism of cataract production by 3-beta(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride, U18666A: an inhibitor of cholesterol biosynthesis. Experimental Eye Research. 28: 673-88. PMID 467524 DOI: 10.1016/0014-4835(79)90068-X |
0.688 |
|
1978 |
Bierkamper GG, Cenedella RJ. Induction of chronic epileptiform activity in the rat by an inhibitor of cholesterol synthesis, U18666A. Brain Research. 150: 343-51. PMID 678974 DOI: 10.1016/0006-8993(78)90285-8 |
0.702 |
|
1978 |
Bierkamper GG, Cenedella RJ. Cerebral cortical cholesterol changes in cobalt-induced epilepsy. Epilepsia. 19: 155-67. PMID 639773 DOI: 10.1111/J.1528-1157.1978.Tb05026.X |
0.705 |
|
1977 |
Kralovic RC, Zepp FA, Cenedella RJ. Studies of the mechanism of carcass fat depletion in experimental cancer. European Journal of Cancer. 13: 1071-9. PMID 923607 DOI: 10.1016/0014-2964(77)90003-2 |
0.328 |
|
1976 |
Galli C, Spagnuolo C, Rodriguez M, Cenedella RJ. Dietary induced modifications of brain polyunsaturated fatty acids and changes of free arachidonic acid release during ischaemia. Advances in Experimental Medicine and Biology. 72: 337-46. PMID 941757 DOI: 10.1007/978-1-4684-0955-0_27 |
0.368 |
|
1976 |
Cenedella RJ. Hepatic triglyceride lipases--effect of clofibrate and halofenate. Biochemical Pharmacology. 25: 2657-61. PMID 10929 DOI: 10.1016/0006-2952(76)90523-2 |
0.347 |
|
1975 |
Cenedella RJ, Crouthamel WG, Bierkamper GG, Westfall DP. Alteration of drug pharmacodynamics by hyperlipidemia. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 218: 299-311. PMID 1212025 |
0.678 |
|
1975 |
Crouthamel WG, Cenedella RJ. Clofibrate pharmacokinetics: effect of elevation of plasma-free fatty acids. Pharmacology. 13: 465-73. PMID 1208648 DOI: 10.1159/000136939 |
0.376 |
|
1974 |
Cenedella RJ, Imrich BJ. Lipolytic activities of intact Walker 256 ascites tumor cells. Lipids. 9: 338-45. PMID 4833197 DOI: 10.1007/Bf02533111 |
0.309 |
|
1974 |
Cenedella RJ, Crouthamel WG. Intestinal versus hepatic contribution to circulating triglyceride levels. Lipids. 9: 35-42. PMID 4810503 DOI: 10.1007/Bf02533211 |
0.392 |
|
1973 |
Cenedella RJ, Craig CR. Changes in cerebral cortical lipids in cobalt-induced epilepsy. Journal of Neurochemistry. 21: 743-8. PMID 4754855 DOI: 10.1111/J.1471-4159.1973.Tb07518.X |
0.442 |
|
1972 |
Beckett RB, Weiss R, Stitzel RE, Cenedella RJ. Studies on the hepatomegaly caused by the hypolipidemic drugs nafenopin and clofibrate. Toxicology and Applied Pharmacology. 23: 42-53. PMID 5071041 DOI: 10.1016/0041-008X(72)90202-5 |
0.33 |
|
1972 |
Cenedella RJ. Clofibrate and nafenopin (SU-13437): effects on plasma clearance and tissue distribution of chylomicron triglyceride in the dog. Lipids. 7: 644-52. PMID 4635558 DOI: 10.1007/Bf02533070 |
0.343 |
|
1971 |
Cenedella RJ. Effects of Su-13437, a new hypolipidemic drug, upon synthesis in vivo of hepatic and carcass total fatty acids and total cholesterol. Lipids. 6: 475-80. PMID 5120787 DOI: 10.1007/Bf02531232 |
0.411 |
|
1971 |
Wagner WD, Peterson RA, Cenedella RJ. The effects of cold and prostaglandin E1 on lipid mobilization in the chicken. Canadian Journal of Physiology and Pharmacology. 49: 394-8. PMID 5120266 DOI: 10.1139/Y71-046 |
0.33 |
|
1971 |
Cenedella RJ. The lipids of the female monarch butterfly, Danaus plexippus, during fall migration Insect Biochemistry. 1: 244-247. DOI: 10.1016/0020-1790(71)90077-1 |
0.366 |
|
1970 |
Cenedella RJ, Jarrell JJ. Suggested new mechanisms of antimalarial action for DDS involving inhibition of glucose utilization by the intraerythrocytic parasite. The American Journal of Tropical Medicine and Hygiene. 19: 592-8. PMID 5425495 DOI: 10.4269/Ajtmh.1970.19.592 |
0.309 |
|
1969 |
Cenedella RJ, Jarrell JJ, Saxe LH. Plasmodium berghei: production in vitro of free fatty acids. Experimental Parasitology. 24: 130-6. PMID 5813414 DOI: 10.1016/0014-4894(69)90149-0 |
0.388 |
|
1969 |
Cenedella RJ, Allen A. Differences between the metabolism of linoleic and palmitic acid: utilization for cholesterol synthesis and oxidation to respiratory CO2. Lipids. 4: 155-8. PMID 5782076 DOI: 10.1007/Bf02531936 |
0.388 |
|
1969 |
Lawrence CW, Cenedella RJ. Lipid content of Plasmodium berghei-infected rat red blood cells. Experimental Parasitology. 26: 181-6. PMID 5401453 DOI: 10.1016/0014-4894(69)90110-6 |
0.411 |
|
1969 |
Cenedella RJ, Marcus LK, Van Dyke K, Saxe LH. Acetylation in vitro of para-aminobenzoic acid by unparasitized and Plasmodium berghei parasitized rat reticulocytes. Experimental Parasitology. 25: 142-5. PMID 5362577 DOI: 10.1016/0014-4894(69)90060-5 |
0.345 |
|
1968 |
Cenedella RJ, Jarrell JJ, Saxe LH. Effects of ethyl-p-chlorophenoxyisobutyrate, clofibrate, on the plasma and red blood cell free fatty acids of the rat. Journal of Atherosclerosis Research. 8: 903-11. PMID 5707796 DOI: 10.1016/S0368-1319(68)80004-3 |
0.396 |
|
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