Mel B. Feany, MD PhD - Publications

Pathology Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States 
 Massachusetts General Hospital, Boston, MA 
 University of Wisconsin, Madison, Madison, WI 
In our laboratory we have created fruit fly models of human neurological diseases, including Alzheimer's disease, Parkinson's disease, and a number of less common disorders

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Maor G, Dubreuil RR, Feany MB. α-synuclein promotes neuronal dysfunction and death by disrupting the binding of ankyrin to ß-spectrin. Biorxiv : the Preprint Server For Biology. PMID 37333277 DOI: 10.1101/2023.06.02.543481  0.304
2023 Hagemann TL, Coyne S, Levin A, Wang L, Feany MB, Messing A. STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease. Cells. 12. PMID 37048051 DOI: 10.3390/cells12070978  0.316
2023 Maor G, Dubreuil RR, Feany MB. α-synuclein promotes neuronal dysfunction and death by disrupting the binding of ankyrin to ß-spectrin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36653193 DOI: 10.1523/JNEUROSCI.1922-22.2022  0.317
2022 Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Feany MB, et al. Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England). PMID 36456723 DOI: 10.1007/s12311-022-01501-5  0.464
2022 Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Feany MB, et al. Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum (London, England). PMID 36190676 DOI: 10.1007/s12311-022-01471-8  0.576
2022 Kim J, Young GS, Willett AS, Pitaro AT, Crotty GF, Mesidor M, Jones KA, Bay C, Zhang M, Feany MB, Xu X, Qin L, Khurana V. Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects. Cerebellum (London, England). PMID 36156185 DOI: 10.1007/s12311-022-01472-7  0.494
2022 Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, ... ... Feany MB, et al. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 185: 2035-2056.e33. PMID 35688132 DOI: 10.1016/j.cell.2022.05.008  0.797
2021 Olsen AL, Feany MB. Parkinson's disease risk genes act in glia to control neuronal α-synuclein toxicity. Neurobiology of Disease. 159: 105482. PMID 34390834 DOI: 10.1016/j.nbd.2021.105482  0.335
2021 Torre M, Dey A, Woods JK, Feany MB. Elevated Oxidative Stress and DNA Damage in Cortical Neurons of Chemotherapy Patients. Journal of Neuropathology and Experimental Neurology. PMID 34363676 DOI: 10.1093/jnen/nlab074  0.736
2021 Sarkar S, Feany MB. Precision medicine on the fly: using Drosophila to decipher gene-environment interactions in Parkinson's disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 34076689 DOI: 10.1093/toxsci/kfab060  0.714
2021 Sarkar S, Bardai F, Olsen AL, Lohr KM, Zhang YY, Feany MB. Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivo. Molecular Neurodegeneration. 16: 33. PMID 34030727 DOI: 10.1186/s13024-021-00454-3  0.781
2021 Sarkar S, Olsen AL, Sygnecka K, Lohr KM, Feany MB. α-synuclein impairs autophagosome maturation through abnormal actin stabilization. Plos Genetics. 17: e1009359. PMID 33556113 DOI: 10.1371/journal.pgen.1009359  0.815
2020 Lohr KM, Frost B, Scherzer C, Feany MB. Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model. Proceedings of the National Academy of Sciences of the United States of America. PMID 33318181 DOI: 10.1073/pnas.1922392117  0.789
2020 Sarkar S, Murphy MA, Dammer EB, Olsen AL, Rangaraju S, Fraenkel E, Feany MB. Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. Npj Parkinson's Disease. 6: 40. PMID 33311497 DOI: 10.1038/s41531-020-00143-w  0.745
2020 Ferenczi EA, Erkkinen MG, Feany MB, Fogel BS, Daffner KR. New-Onset Delusions Heralding an Underlying Neurodegenerative Condition: A Case Report and Review of the Literature. The Journal of Clinical Psychiatry. 81. PMID 32237299 DOI: 10.4088/Jcp.19R13027  0.36
2020 Sarkar S, Maor G, Feany MB. Multiplex analysis in a Drosophila gene‐environment model identifies interactions among LRRK2, rotenone and α‐synuclein The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00692  0.688
2019 Olsen AL, Feany MB. Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo. Glia. PMID 31267577 DOI: 10.1002/Glia.23671  0.404
2019 Olsen AL, Feany MB. PARP Inhibitors and Parkinson's Disease. The New England Journal of Medicine. 380: 492-494. PMID 30699325 DOI: 10.1056/Nejmcibr1814680  0.386
2018 Bardai FH, Ordonez DG, Bailey RM, Hamm M, Lewis J, Feany MB. Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics. Plos Biology. 16: e2006265. PMID 30571694 DOI: 10.1371/Journal.Pbio.2006265  0.794
2018 Wang L, Xia J, Li J, Hagemann TL, Jones JR, Fraenkel E, Weitz DA, Zhang SC, Messing A, Feany MB. Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease. Nature Communications. 9: 1899. PMID 29765022 DOI: 10.1038/S41467-018-04269-7  0.43
2017 Ordonez DG, Lee MK, Feany MB. α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton. Neuron. PMID 29249285 DOI: 10.1016/J.Neuron.2017.11.036  0.788
2017 Bardai FH, Wang L, Mutreja Y, Yenjerla M, Gamblin TC, Feany MB. A conserved cytoskeletal signaling cascade mediates neurotoxicity of FTDP-17 tau mutations in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29138281 DOI: 10.1523/Jneurosci.1550-17.2017  0.816
2017 Collier TJ, Srivastava KR, Justman C, Grammatopoulous T, Hutter-Paier B, Prokesch M, Havas D, Rochet JC, Liu F, Jock K, de Oliveira P, Stirtz GL, Dettmer U, Sortwell CE, Feany MB, et al. Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Neurobiology of Disease. PMID 28711409 DOI: 10.1016/J.Nbd.2017.07.007  0.396
2016 Etchegaray JI, Elguero EJ, Tran JA, Sinatra V, Feany MB, McCall K. Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3170-83. PMID 26985028 DOI: 10.1523/Jneurosci.1912-15.2016  0.627
2016 Wang L, Hagemann TL, Messing A, Feany MB. An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1445-55. PMID 26843629 DOI: 10.1523/Jneurosci.0256-15.2016  0.411
2015 Frost B, Bardai FH, Feany MB. Lamin Dysfunction Mediates Neurodegeneration in Tauopathies. Current Biology : Cb. PMID 26725200 DOI: 10.1016/J.Cub.2015.11.039  0.824
2015 Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, ... ... Feany M, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/S00401-015-1509-X  0.391
2015 Wang L, Hagemann TL, Kalwa H, Michel T, Messing A, Feany MB. Nitric oxide mediates glial-induced neurodegeneration in Alexander disease. Nature Communications. 6: 8966. PMID 26608817 DOI: 10.1038/Ncomms9966  0.448
2015 Frost B, Götz J, Feany MB. Connecting the dots between tau dysfunction and neurodegeneration. Trends in Cell Biology. 25: 46-53. PMID 25172552 DOI: 10.1016/J.Tcb.2014.07.005  0.664
2014 Merlo P, Frost B, Peng S, Yang YJ, Park PJ, Feany M. p53 prevents neurodegeneration by regulating synaptic genes. Proceedings of the National Academy of Sciences of the United States of America. 111: 18055-60. PMID 25453105 DOI: 10.1073/Pnas.1419083111  0.594
2014 Hegde VR, Vogel R, Feany MB. Glia are critical for the neuropathology of complex I deficiency in Drosophila. Human Molecular Genetics. 23: 4686-92. PMID 24760769 DOI: 10.1093/Hmg/Ddu188  0.433
2014 Frost B, Hemberg M, Lewis J, Feany MB. Tau promotes neurodegeneration through global chromatin relaxation. Nature Neuroscience. 17: 357-66. PMID 24464041 DOI: 10.1038/Nn.3639  0.674
2014 Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/Hmg/Ddt478  0.413
2013 Mannix R, Meehan WP, Mandeville J, Grant PE, Gray T, Berglass J, Zhang J, Bryant J, Rezaie S, Chung JY, Peters NV, Lee C, Tien LW, Kaplan DL, Feany M, et al. Clinical correlates in an experimental model of repetitive mild brain injury. Annals of Neurology. 74: 65-75. PMID 23922306 DOI: 10.1002/Ana.23858  0.303
2013 DuBoff B, Feany M, Götz J. Why size matters - balancing mitochondrial dynamics in Alzheimer's disease. Trends in Neurosciences. 36: 325-35. PMID 23582339 DOI: 10.1016/J.Tins.2013.03.002  0.795
2013 Imboywa S, Diamond A, Chipendo P, De Jager P, Shulman JM, Feany M. P2-033: Intergrating human and fly genetics to understand Alzheimer's disease susceptibility Alzheimer's & Dementia. 9: P356-P356. DOI: 10.1016/J.Jalz.2013.05.675  0.383
2012 DuBoff B, Götz J, Feany MB. Tau promotes neurodegeneration via DRP1 mislocalization in vivo. Neuron. 75: 618-32. PMID 22920254 DOI: 10.1016/J.Neuron.2012.06.026  0.802
2012 Ryan EL, DuBoff B, Feany MB, Fridovich-Keil JL. Mediators of a long-term movement abnormality in a Drosophila melanogaster model of classic galactosemia. Disease Models & Mechanisms. 5: 796-803. PMID 22736462 DOI: 10.1242/Dmm.009050  0.751
2012 Khurana V, Merlo P, DuBoff B, Fulga TA, Sharp KA, Campbell SD, Götz J, Feany MB. A neuroprotective role for the DNA damage checkpoint in tauopathy. Aging Cell. 11: 360-2. PMID 22181010 DOI: 10.1111/J.1474-9726.2011.00778.X  0.769
2011 Wang L, Colodner KJ, Feany MB. Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2868-77. PMID 21414908 DOI: 10.1523/Jneurosci.3410-10.2011  0.806
2011 Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. American Journal of Human Genetics. 88: 232-8. PMID 21295279 DOI: 10.1016/J.Ajhg.2011.01.006  0.35
2011 Shulman JM, De Jager PL, Feany MB. Parkinson's disease: genetics and pathogenesis. Annual Review of Pathology. 6: 193-222. PMID 21034221 DOI: 10.1146/Annurev-Pathol-011110-130242  0.38
2010 Colodner KJ, Feany MB. Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16102-13. PMID 21123557 DOI: 10.1523/Jneurosci.2491-10.2010  0.812
2010 Loewen CA, Feany MB. The unfolded protein response protects from tau neurotoxicity in vivo. Plos One. 5. PMID 20927324 DOI: 10.1371/Journal.Pone.0013084  0.387
2010 Pienaar IS, Götz J, Feany MB. Parkinson's disease: insights from non-traditional model organisms. Progress in Neurobiology. 92: 558-71. PMID 20851733 DOI: 10.1016/J.Pneurobio.2010.09.001  0.365
2010 Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynelä J, Scherzer CR, Feany MB. Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo. Plos Genetics. 6: e1001026. PMID 20664788 DOI: 10.1371/Journal.Pgen.1001026  0.8
2010 Feany MB. ASIP Outstanding Investigator Award Lecture. New approaches to the pathology and genetics of neurodegeneration. The American Journal of Pathology. 176: 2058-66. PMID 20363919 DOI: 10.2353/Ajpath.2010.091077  0.447
2010 Feany M. PL-05-02: Drosophila models of Alzheimer's disease and related disorders Alzheimer's & Dementia. 6: S165-S165. DOI: 10.1016/J.Jalz.2010.05.514  0.389
2009 Chen L, Periquet M, Wang X, Negro A, McLean PJ, Hyman BT, Feany MB. Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. The Journal of Clinical Investigation. 119: 3257-65. PMID 19855133 DOI: 10.1172/Jci39088  0.393
2009 McFarland NR, Fan Z, Xu K, Schwarzschild MA, Feany MB, Hyman BT, McLean PJ. Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease. Journal of Neuropathology and Experimental Neurology. 68: 515-24. PMID 19525899 DOI: 10.1097/Nen.0B013E3181A24B53  0.372
2009 Zhang S, Feany MB, Saraswati S, Littleton JT, Perrimon N. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Disease Models & Mechanisms. 2: 247-66. PMID 19380309 DOI: 10.1242/Dmm.000653  0.402
2009 Cullen V, Lindfors M, Ng J, Paetau A, Swinton E, Kolodziej P, Boston H, Saftig P, Woulfe J, Feany MB, Myllykangas L, Schlossmacher MG, Tyynelä J. Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. Molecular Brain. 2: 5. PMID 19203374 DOI: 10.1186/1756-6606-2-5  0.394
2009 Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR, Perrin S, Feany MB, Horwich AL. Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Proceedings of the National Academy of Sciences of the United States of America. 106: 1392-7. PMID 19171884 DOI: 10.1073/Pnas.0813045106  0.326
2009 Feany MB, DuBoff B. 9. Tau causes neurodegeneration in vivo through mitochondrial disruption Mitochondrion. 9: 63. DOI: 10.1016/J.Mito.2008.12.010  0.79
2008 Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, Wu HY, Osetek JD, Jones PB, Bacskai BJ, Feany MB, Carlson GA, Ashe KH, Lewis J, Hyman BT. In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 862-7. PMID 18216194 DOI: 10.1523/Jneurosci.3072-08.2008  0.372
2008 Feany M. S2-03-05: The role of actin and oxidative stress in tau-associated neurodegeneration Alzheimer's & Dementia. 4: T127-T127. DOI: 10.1016/J.Jalz.2008.05.287  0.34
2007 Steinhilb ML, Dias-Santagata D, Fulga TA, Felch DL, Feany MB. Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Molecular Biology of the Cell. 18: 5060-8. PMID 17928404 DOI: 10.1091/Mbc.E07-04-0327  0.443
2007 Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science (New York, N.Y.). 317: 516-9. PMID 17588900 DOI: 10.1126/Science.1143780  0.643
2007 Dufty BM, Warner LR, Hou ST, Jiang SX, Gomez-Isla T, Leenhouts KM, Oxford JT, Feany MB, Masliah E, Rohn TT. Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. The American Journal of Pathology. 170: 1725-38. PMID 17456777 DOI: 10.2353/Ajpath.2007.061232  0.344
2007 Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB. Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3338-46. PMID 17376994 DOI: 10.1523/Jneurosci.0285-07.2007  0.44
2007 Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB. S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. Journal of Neuroscience Research. 85: 1271-8. PMID 17335084 DOI: 10.1002/Jnr.21232  0.387
2007 Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nature Cell Biology. 9: 139-48. PMID 17187063 DOI: 10.1038/Ncb1528  0.808
2007 Dias-Santagata D, Fulga TA, Duttaroy A, Feany MB. Oxidative stress mediates tau-induced neurodegeneration in Drosophila. The Journal of Clinical Investigation. 117: 236-45. PMID 17173140 DOI: 10.1172/Jci28769  0.377
2007 Khurana V, Feany MB. Connecting cell-cycle activation to neurodegeneration in Drosophila. Biochimica Et Biophysica Acta. 1772: 446-56. PMID 17141486 DOI: 10.1016/J.Bbadis.2006.10.007  0.613
2006 Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12408-14. PMID 17135402 DOI: 10.1523/Jneurosci.3372-06.2006  0.646
2006 Kontopoulos E, Parvin JD, Feany MB. Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Human Molecular Genetics. 15: 3012-23. PMID 16959795 DOI: 10.1093/Hmg/Ddl243  0.607
2006 Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Current Biology : Cb. 16: 230-41. PMID 16461276 DOI: 10.1016/J.Cub.2005.12.042  0.629
2006 Orso G, Martinuzzi A, Rossetto MG, Sartori E, Feany M, Daga A. Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. The Journal of Clinical Investigation. 115: 3026-34. PMID 16276413 DOI: 10.1172/Jci24694  0.431
2005 Khurana V, Fulga TA, Feany MB. Senseless makes sense for spinocerebellar ataxia-1. Nature Neuroscience. 8: 1422-4. PMID 16251977 DOI: 10.1038/Nn1105-1422  0.63
2005 Myllykangas L, Tyynelä J, Page-McCaw A, Rubin GM, Haltia MJ, Feany MB. Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses. Neurobiology of Disease. 19: 194-9. PMID 15837574 DOI: 10.1016/J.Nbd.2004.12.019  0.367
2005 Chen L, Feany MB. Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nature Neuroscience. 8: 657-63. PMID 15834418 DOI: 10.1038/Nn1443  0.437
2005 Colodner KJ, Montana RA, Anthony DC, Folkerth RD, De Girolami U, Feany MB. Proliferative potential of human astrocytes. Journal of Neuropathology and Experimental Neurology. 64: 163-9. PMID 15751231 DOI: 10.1093/Jnen/64.2.163  0.762
2004 Feany MB. New genetic insights into Parkinson's disease. The New England Journal of Medicine. 351: 1937-40. PMID 15525720 DOI: 10.1056/Nejmp048263  0.387
2004 Ghosh S, Feany MB. Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Human Molecular Genetics. 13: 2011-8. PMID 15254017 DOI: 10.1093/Hmg/Ddh214  0.452
2004 Scherzer CR, Feany MB. Yeast genetics targets lipids in Parkinson's disease. Trends in Genetics : Tig. 20: 273-7. PMID 15219388 DOI: 10.1016/J.Tig.2004.05.005  0.43
2003 Shulman JM, Feany MB. Genetic modifiers of tauopathy in Drosophila. Genetics. 165: 1233-42. PMID 14668378  0.385
2003 Scherzer CR, Jensen RV, Gullans SR, Feany MB. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Human Molecular Genetics. 12: 2457-66. PMID 12915459 DOI: 10.1093/Hmg/Ddg265  0.414
2003 Shulman JM, Shulman LM, Weiner WJ, Feany MB. From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Current Opinion in Neurology. 16: 443-9. PMID 12869801 DOI: 10.1097/01.Wco.0000084220.82329.60  0.442
2003 Deleault NR, Dolph PJ, Feany MB, Cook ME, Nishina K, Harris DA, Supattapone S. Post-transcriptional suppression of pathogenic prion protein expression in Drosophila neurons. Journal of Neurochemistry. 85: 1614-23. PMID 12787080 DOI: 10.1046/J.1471-4159.2003.01819.X  0.438
2003 Feany MB, Pallanck LJ. Parkin: a multipurpose neuroprotective agent? Neuron. 38: 13-6. PMID 12691660 DOI: 10.1016/S0896-6273(03)00201-0  0.467
2003 Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proceedings of the National Academy of Sciences of the United States of America. 100: 4078-83. PMID 12642658 DOI: 10.1073/Pnas.0737556100  0.42
2002 Muqit MM, Feany MB. Modelling neurodegenerative diseases in Drosophila: a fruitful approach? Nature Reviews. Neuroscience. 3: 237-43. PMID 11994755 DOI: 10.1038/Nrn751  0.461
2001 Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, Hutton M, Feany MB. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science (New York, N.Y.). 293: 711-4. PMID 11408621 DOI: 10.1126/Science.1062382  0.515
2000 Feany MB. Studying human neurodegenerative diseases in flies and worms. Journal of Neuropathology and Experimental Neurology. 59: 847-56. PMID 11079774 DOI: 10.1093/Jnen/59.10.847  0.377
2000 Feany MB, Bender WW. A Drosophila model of Parkinson's disease. Nature. 404: 394-8. PMID 10746727 DOI: 10.1038/35006074  0.657
1996 Dickson DW, Feany MB, Yen SH, Mattiace LA, Davies P. Cytoskeletal pathology in non-Alzheimer degenerative dementia: new lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration. Journal of Neural Transmission. Supplementum. 47: 31-46. PMID 8841955 DOI: 10.1007/978-3-7091-6892-9_2  0.45
1996 Feany MB, Dickson DW. Neurodegenerative disorders with extensive tau pathology: a comparative study and review. Annals of Neurology. 40: 139-48. PMID 8773594 DOI: 10.1002/Ana.410400204  0.439
1996 Feany MB, Mattiace LA, Dickson DW. Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration. Journal of Neuropathology and Experimental Neurology. 55: 53-67. PMID 8558172 DOI: 10.1097/00005072-199601000-00006  0.419
1996 Dickson DW, Feany MB. 10 Corticobasal degeneration versus Picks' disease: An immunocytochemical comparison Neurobiology of Aging. 17: S3. DOI: 10.1016/S0197-4580(96)80012-1  0.371
1995 Feany MB, Dickson DW. Widespread cytoskeletal pathology characterizes corticobasal degeneration. The American Journal of Pathology. 146: 1388-96. PMID 7778678  0.376
1995 Feany MB, Ksiezak-Reding H, Liu WK, Vincent I, Yen SH, Dickson DW. Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy. Acta Neuropathologica. 90: 37-43. PMID 7572077 DOI: 10.1007/Bf00294457  0.424
1993 Feany MB, Buckley KM. The synaptic vesicle protein synaptotagmin promotes formation of filopodia in fibroblasts. Nature. 364: 537-40. PMID 8166886 DOI: 10.1038/364537A0  0.588
1993 Feany MB, Yee AG, Delvy ML, Buckley KM. The synaptic vesicle proteins SV2, synaptotagmin and synaptophysin are sorted to separate cellular compartments in CHO fibroblasts. The Journal of Cell Biology. 123: 575-84. PMID 7901222 DOI: 10.1083/Jcb.123.3.575  0.556
1992 Feany MB, Lee S, Edwards RH, Buckley KM. The synaptic vesicle protein SV2 is a novel type of transmembrane transporter. Cell. 70: 861-7. PMID 1355409 DOI: 10.1016/0092-8674(92)90319-8  0.539
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