Barbara J. Caldarone - Publications

PsychoGenics Inc, Tarrytown, NY, United States 
Molecular Psychiatry

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Rennekamp AJ, Huang XP, Wang Y, Patel S, Lorello PJ, Cade L, Gonzales AP, Yeh JJ, Caldarone BJ, Roth BL, Kokel D, Peterson RT. σ1 receptor ligands control a switch between passive and active threat responses. Nature Chemical Biology. PMID 27239788 DOI: 10.1038/nchembio.2089  1
2016 Bruni G, Rennekamp AJ, Velenich A, McCarroll M, Gendelev L, Fertsch E, Taylor J, Lakhani P, Lensen D, Evron T, Lorello PJ, Huang XP, Kolczewski S, Carey G, Caldarone BJ, et al. Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds. Nature Chemical Biology. PMID 27239787 DOI: 10.1038/nchembio.2097  1
2016 Onajole OK, Vallerini GP, Eaton JB, Lukas RJ, Brunner D, Caldarone BJ, Kozikowski AP. Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III. Acs Chemical Neuroscience. PMID 27035276 DOI: 10.1021/acschemneuro.6b00050  1
2015 Frost JL, Liu B, Rahfeld JU, Kleinschmidt M, O'Nuallain B, Le KX, Lues I, Caldarone BJ, Schilling S, Demuth HU, Lemere CA. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. Neurobiology of Aging. PMID 26453001 DOI: 10.1016/j.neurobiolaging.2015.08.021  1
2015 Mably AJ, Kanmert D, Mc Donald JM, Liu W, Caldarone BJ, Lemere CA, O'Nuallain B, Kosik KS, Walsh DM. Tau immunization: a cautionary tale? Neurobiology of Aging. 36: 1316-32. PMID 25619661 DOI: 10.1016/j.neurobiolaging.2014.11.022  1
2015 Caldarone BJ, Zachariou V, King SL. Rodent models of treatment-resistant depression. European Journal of Pharmacology. 753: 51-65. PMID 25460020 DOI: 10.1016/j.ejphar.2014.10.063  1
2014 Onajole OK, Eaton JB, Lukas RJ, Brunner D, Thiede L, Caldarone BJ, Kozikowski AP. Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands. Acs Medicinal Chemistry Letters. 5: 1196-201. PMID 25408831 DOI: 10.1021/ml500129k  1
2014 Yu LF, Zhang HK, Caldarone BJ, Eaton JB, Lukas RJ, Kozikowski AP. Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 57: 8204-23. PMID 24901260 DOI: 10.1021/jm401937a  1
2013 Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proceedings of the National Academy of Sciences of the United States of America. 110: 8254-9. PMID 23630294 DOI: 10.1073/pnas.1214696110  1
2013 Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling is a crucial modulator of antidepressant drug action in depression and neuropathic pain models(Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 20 (8254-8259)) Proceedings of the National Academy of Sciences of the United States of America. 110: 11660. DOI: 10.1073/pnas.1311399110  1
2012 Yu LF, Tückmantel W, Eaton JB, Caldarone B, Fedolak A, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity. Journal of Medicinal Chemistry. 55: 812-23. PMID 22148173 DOI: 10.1021/jm201301h  1
2012 Brunner D, Alexandrov V, Caldarone B, Hanania T, Lowe D, Schneider J, Chandrasekhar J. Behavior-Based Screening as an Approach to Polypharmacological Ligands Polypharmacology in Drug Discovery. 303-313. DOI: 10.1002/9781118098141.ch14  1
2011 Kozikowski AP, Gunosewoyo H, Guo S, Gaisina IN, Walter RL, Ketcherside A, McClung CA, Mesecar AD, Caldarone B. Identification of a glycogen synthase kinase-3β inhibitor that attenuates hyperactivity in CLOCK mutant mice. Chemmedchem. 6: 1593-602. PMID 21732538 DOI: 10.1002/cmdc.201100188  1
2011 Caldarone BJ, Wang D, Paterson NE, Manzano M, Fedolak A, Cavino K, Kwan M, Hanania T, Chellappan SK, Kozikowski AP, Olivier B, Picciotto MR, Ghavami A. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380. Psychopharmacology. 217: 199-210. PMID 21487659 DOI: 10.1007/s00213-011-2271-y  1
2010 Caldarone BJ, Paterson NE, Zhou J, Brunner D, Kozikowski AP, Westphal KG, Korte-Bouws GA, Prins J, Korte SM, Olivier B, Ghavami A. The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties. The Journal of Pharmacology and Experimental Therapeutics. 335: 762-70. PMID 20864506 DOI: 10.1124/jpet.110.174011  1
2010 Liu J, Eaton JB, Caldarone B, Lukas RJ, Kozikowski AP. Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists. Journal of Medicinal Chemistry. 53: 6973-85. PMID 20822184 DOI: 10.1021/jm100765u  1
2010 Paterson NE, Min W, Hackett A, Lowe D, Hanania T, Caldarone B, Ghavami A. The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 1455-64. PMID 20708056 DOI: 10.1016/j.pnpbp.2010.07.037  1
2010 Paterson NE, Fedolak A, Olivier B, Hanania T, Ghavami A, Caldarone B. Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents. Pharmacology, Biochemistry, and Behavior. 95: 449-56. PMID 20346966 DOI: 10.1016/j.pbb.2010.03.006  1
2009 Kozikowski AP, Eaton JB, Bajjuri KM, Chellappan SK, Chen Y, Karadi S, He R, Caldarone B, Manzano M, Yuen PW, Lukas RJ. Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression. Chemmedchem. 4: 1279-91. PMID 19569163 DOI: 10.1002/cmdc.200900079  1
2009 Cho SJ, Jensen NH, Kurome T, Kadari S, Manzano ML, Malberg JE, Caldarone B, Roth BL, Kozikowski AP. Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: identification of drugs with antidepressant-like action. Journal of Medicinal Chemistry. 52: 1885-902. PMID 19284718 DOI: 10.1021/jm801354e  1
2009 Traynor JR, Terzi D, Caldarone BJ, Zachariou V. RGS9-2: probing an intracellular modulator of behavior as a drug target. Trends in Pharmacological Sciences. 30: 105-11. PMID 19211160 DOI: 10.1016/  1
2008 Caldarone BJ, King SL, Picciotto MR. Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice. Neuroscience Letters. 439: 187-91. PMID 18524488 DOI: 10.1016/j.neulet.2008.05.023  1
2007 Kozikowski AP, Gaisina IN, Yuan H, Petukhov PA, Blond SY, Fedolak A, Caldarone B, McGonigle P. Structure-based design leads to the identification of lithium mimetics that block mania-like effects in rodents. possible new GSK-3beta therapies for bipolar disorders. Journal of the American Chemical Society. 129: 8328-32. PMID 17552518 DOI: 10.1021/ja068969w  1
2007 Lynch WJ, Kiraly DD, Caldarone BJ, Picciotto MR, Taylor JR. Effect of cocaine self-administration on striatal PKA-regulated signaling in male and female rats. Psychopharmacology. 191: 263-71. PMID 17180335 DOI: 10.1007/s00213-006-0656-0  1
2006 Rabenstein RL, Caldarone BJ, Picciotto MR. The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacology. 189: 395-401. PMID 17016705 DOI: 10.1007/s00213-006-0568-z  1
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/j.neuron.2006.07.025  1
2005 Kerber CS, Desai RA, Maciejewski PK, Dausey DJ, Caldarone BJ, Potenza MN. Defining "health correlates" in recreational gambling [5] (multiple letters) American Journal of Psychiatry. 162: 1227-1228. PMID 15930082 DOI: 10.1176/appi.ajp.162.6.1227  1
2005 Rabenstein RL, Addy NA, Caldarone BJ, Asaka Y, Gruenbaum LM, Peters LL, Gilligan DM, Fitzsimonds RM, Picciotto MR. Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2138-45. PMID 15728854 DOI: 10.1523/JNEUROSCI.3530-04.2005  1
2004 Caldarone BJ, Harrist A, Cleary MA, Beech RD, King SL, Picciotto MR. High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biological Psychiatry. 56: 657-64. PMID 15522249 DOI: 10.1016/j.biopsych.2004.08.010  1
2004 Harrist A, Beech RD, King SL, Zanardi A, Cleary MA, Caldarone BJ, Eisch A, Zoli M, Picciotto MR. Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor. Synapse (New York, N.Y.). 54: 200-6. PMID 15472930 DOI: 10.1002/syn.20081  1
2004 King SL, Caldarone BJ, Picciotto MR. Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration. Neuropharmacology. 47: 132-9. PMID 15464132 DOI: 10.1016/j.neuropharm.2004.06.024  1
2004 Desai RA, Maciejewski PK, Dausey DJ, Caldarone BJ, Potenza MN. Health correlates of recreational gambling in older adults. The American Journal of Psychiatry. 161: 1672-9. PMID 15337659 DOI: 10.1176/appi.ajp.161.9.1672  1
2003 Mongeluzi DL, Rosellini RA, Ley R, Caldarone BJ, Stock HS. The conditioning of dyspneic suffocation fear. Effects of carbon dioxide concentration on behavioral freezing and analgesia. Behavior Modification. 27: 620-36. PMID 14531158 DOI: 10.1177/0145445503256316  1
2003 Caldarone BJ, Karthigeyan K, Harrist A, Hunsberger JG, Wittmack E, King SL, Jatlow P, Picciotto MR. Sex differences in response to oral amitriptyline in three animal models of depression in C57BL/6J mice. Psychopharmacology. 170: 94-101. PMID 12879206 DOI: 10.1007/s00213-003-1518-7  1
2003 King SL, Marks MJ, Grady SR, Caldarone BJ, Koren AO, Mukhin AG, Collins AC, Picciotto MR. Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3837-43. PMID 12736354  1
2002 Picciotto MR, Brunzell DH, Caldarone BJ. Effect of nicotine and nicotinic receptors on anxiety and depression. Neuroreport. 13: 1097-106. PMID 12151749  1
2002 Di Paolo G, Sankaranarayanan S, Wenk MR, Daniell L, Perucco E, Caldarone BJ, Flavell R, Picciotto MR, Ryan TA, Cremona O, De Camilli P. Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron. 33: 789-804. PMID 11879655 DOI: 10.1016/S0896-6273(02)00601-3  1
2001 Picciotto MR, Caldarone BJ, Brunzell DH, Zachariou V, Stevens TR, King SL. Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacology & Therapeutics. 92: 89-108. PMID 11916531 DOI: 10.1016/S0163-7258(01)00161-9  1
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  1
2001 Stock HS, Caldarone B, Abrahamsen G, Mongeluzi D, Wilson MA, Rosellini RA. Sex differences in relation to conditioned fear-induced enhancement of morphine analgesia. Physiology & Behavior. 72: 439-47. PMID 11274689 DOI: 10.1016/S0031-9384(00)00426-1  1
2000 Bolivar VJ, Caldarone BJ, Reilly AA, Flaherty L. Habituation of activity in an open field: A survey of inbred strains and F1 hybrids. Behavior Genetics. 30: 285-93. PMID 11206083 DOI: 10.1023/A:1026545316455  1
2000 Caldarone BJ, Duman CH, Picciotto MR. Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology. 39: 2779-84. PMID 11044747 DOI: 10.1016/S0028-3908(00)00137-4  1
2000 Caldarone BJ, George TP, Zachariou V, Picciotto MR. Gender differences in learned helplessness behavior are influenced by genetic background. Pharmacology, Biochemistry, and Behavior. 66: 811-7. PMID 10973520 DOI: 10.1016/S0091-3057(00)00271-9  1
2000 Picciotto MR, Caldarone BJ, King SL, Zachariou V. Nicotinic receptors in the brain. Links between molecular biology and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 451-65. PMID 10731620 DOI: 10.1016/S0893-133X(99)00146-3  1
1998 Abrahamsen GC, Caldarone BJ, Stock HS, Mongeluzi DM, Rosellini RA. Opiate withdrawal-like behavior induced by naloxone following exposure to a contextual fear stimulus Progress in Neuro-Psychopharmacology and Biological Psychiatry. 22: 1303-1316. DOI: 10.1016/S0278-5846(98)00071-2  1
1997 Caldarone BJ, Abrahamsen GC, Stock HS, Mongeluzi DL, Rossellini RA. Enhancement of morphine analgesia in rats following removal from contextual conditioned fear cues. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 21: 981-95. PMID 9380793 DOI: 10.1016/S0278-5846(97)00093-6  1
1997 Caldarone B, Saavedra C, Tartaglia K, Wehner JM, Dudek BC, Flaherty L. Quantitative trait loci analysis affecting contextual conditioning in mice. Nature Genetics. 17: 335-7. PMID 9354801 DOI: 10.1038/ng1197-335  1
1996 Mongeluzi DL, Rosellini RA, Caldarone BJ, Stock HS, Abrahamsen GC. Pavlovian aversive context conditioning using carbon dioxide as the unconditional stimulus. Journal of Experimental Psychology. Animal Behavior Processes. 22: 244-57. PMID 8691156  1
1996 Caldarone BJ, Stock HS, Abrahamsen GC, Boechler ML, Svare BB, Rosellini RA. Nonassociative processes and place preferences conditioned by testosterone Psychological Record. 46: 373-390.  1
1995 Abrahamsen GC, Caldarone BJ, Stock HS, Schutz AD, Rosellini RA. Conditioned fear exacerbates acute morphine dependence. Pharmacology, Biochemistry, and Behavior. 51: 407-13. PMID 7667361 DOI: 10.1016/0091-3057(94)00415-F  1
1994 Rosellini RA, Abrahamsen GC, Stock HS, Caldarone BJ. Modulation of hypoalgesia by morphine and number of shock trials: covariation of a measure of context fear and hypoalgesia. Physiology & Behavior. 56: 183-8. PMID 8084899 DOI: 10.1016/0031-9384(94)90277-1  1
1993 Abrahamsen GC, Stock HS, Caldarone BJ, Rosellini RA. Learned helplessness inducing foot shock can exacerbate morphine responsiveness. Physiology & Behavior. 54: 289-94. PMID 8372123 DOI: 10.1016/0031-9384(93)90113-T  1
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