| Year |
Citation |
Score |
| 2023 |
Dynes JL, Yeromin AV, Cahalan MD. Photoswitching alters fluorescence readout of jGCaMP8 Ca indicators tethered to Orai1 channels. Proceedings of the National Academy of Sciences of the United States of America. 120: e2309328120. PMID 37729200 DOI: 10.1073/pnas.2309328120 |
0.308 |
|
| 2022 |
Cahalan MD. Voltage-gated Ca channel proteins do not function as ion channels in T cells. Science Signaling. 15: eabq5594. PMID 35700266 DOI: 10.1126/scisignal.abq5594 |
0.392 |
|
| 2022 |
Jairaman A, McQuade A, Granzotto A, Kang YJ, Chadarevian JP, Gandhi S, Parker I, Smith I, Cho H, Sensi SL, Othy S, Blurton-Jones M, Cahalan MD. TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia. Elife. 11. PMID 35191835 DOI: 10.7554/eLife.73021 |
0.649 |
|
| 2021 |
Jairaman A, Cahalan MD. Calcium Imaging in T Lymphocytes: a Protocol for Use with Genetically Encoded or Chemical Ca Indicators. Bio-Protocol. 11: e4170. PMID 34722817 DOI: 10.21769/BioProtoc.4170 |
0.347 |
|
| 2021 |
Jairaman A, Othy S, Dynes JL, Yeromin AV, Zavala A, Greenberg ML, Nourse JL, Holt JR, Cahalan SM, Marangoni F, Parker I, Pathak MM, Cahalan MD. Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4 T cell responses. Science Advances. 7. PMID 34233878 DOI: 10.1126/sciadv.abg5859 |
0.313 |
|
| 2020 |
Wakida NM, Gomez-Godinez V, Li H, Nguyen J, Kim EK, Dynes JL, Othy S, Lau AL, Ding P, Shi L, Carmona C, Thompson LM, Cahalan MD, Berns MW. Calcium Dynamics in Astrocytes During Cell Injury. Frontiers in Bioengineering and Biotechnology. 8: 912. PMID 32984268 DOI: 10.3389/Fbioe.2020.00912 |
0.39 |
|
| 2020 |
Othy S, Jairaman A, Dynes JL, Dong TX, Tune C, Yeromin AV, Zavala A, Akunwafo C, Chen F, Parker I, Cahalan MD. Regulatory T cells suppress Th17 cell Ca signaling in the spinal cord during murine autoimmune neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32732436 DOI: 10.1073/Pnas.2006895117 |
0.434 |
|
| 2020 |
Dynes JL, Yeromin AV, Cahalan MD. Cell-wide mapping of Orai1 channel activity reveals functional heterogeneity in STIM1-Orai1 puncta. The Journal of General Physiology. 152. PMID 32589186 DOI: 10.1085/Jgp.201812239 |
0.475 |
|
| 2020 |
McIntyre LL, Greilach SA, Othy S, Sears-Kraxberger I, Wi B, Ayala-Angulo J, Vu E, Pham Q, Silva J, Dang K, Rezk F, Steward O, Cahalan MD, Lane TE, Walsh CM. Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant. Neurobiology of Disease. 104868. PMID 32276110 DOI: 10.1016/J.Nbd.2020.104868 |
0.355 |
|
| 2019 |
Hernández-Ruiz M, Othy S, Herrera C, Nguyen HT, Arrevillaga-Boni G, Catalan-Dibene J, Cahalan MD, Zlotnik A. Cxcl17 mice develop exacerbated disease in a T cell-dependent autoimmune model. Journal of Leukocyte Biology. PMID 30860634 DOI: 10.1002/Jlb.3A0918-345Rr |
0.394 |
|
| 2019 |
Skupsky J, Hwang M, Zavala A, Nakasaki M, Sabui S, Said H, Cahalan M, Newman A, Ransom J, Greenberg ML. P137 LOCAL CRAC CHANNEL BLOCKADE TREATS COLITIS IN MICE Gastroenterology. 156: S92. DOI: 10.1053/J.Gastro.2019.01.214 |
0.308 |
|
| 2017 |
Dong TX, Othy S, Jairaman A, Skupsky J, Zavala A, Parker I, Dynes JL, Cahalan MD. T cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse. Elife. 6. PMID 29239725 DOI: 10.7554/Elife.32417 |
0.485 |
|
| 2017 |
Dong TX, Othy S, Greenberg ML, Jairaman A, Akunwafo C, Leverrier S, Yu Y, Parker I, Dynes JL, Cahalan MD. Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility. Elife. 6. PMID 29239723 DOI: 10.7554/Elife.27827 |
0.503 |
|
| 2017 |
Skupsky J, Othy S, Yeromin A, Dong T, Newman A, Greenberg M, Cahalan M. A Novel Orai1 Calcium Channel Inhibitor as Oral Therapy for Colitis Gastroenterology. 152: S1311. DOI: 10.1016/S0016-5085(17)34364-0 |
0.302 |
|
| 2016 |
Cahalan MD, Othy S, Skupsky J, Parker I. Dynamics of Regulatory T Cell-Mediated Control of Antigen Responses and Autoimmune Neuroinflammation Journal of Allergy and Clinical Immunology. 137: AB269. DOI: 10.1016/J.Jaci.2015.12.1020 |
0.367 |
|
| 2015 |
Dynes JL, Amcheslavsky A, Cahalan MD. Genetically targeted single-channel optical recording reveals multiple Orai1 gating states and oscillations in calcium influx. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712003 DOI: 10.1073/Pnas.1523410113 |
0.773 |
|
| 2015 |
Perni S, Dynes JL, Yeromin AV, Cahalan MD, Franzini-Armstrong C. Nanoscale patterning of STIM1 and Orai1 during store-operated Ca2+ entry. Proceedings of the National Academy of Sciences of the United States of America. 112: E5533-42. PMID 26351694 DOI: 10.1073/Pnas.1515606112 |
0.403 |
|
| 2015 |
Weinger JG, Greenberg ML, Matheu MP, Parker I, Walsh CM, Lane TE, Cahalan MD. Two-photon imaging of cellular dynamics in the mouse spinal cord. Journal of Visualized Experiments : Jove. PMID 25742043 DOI: 10.3791/52580 |
0.714 |
|
| 2015 |
Matheu MP, Othy S, Greenberg ML, Dong TX, Schuijs M, Deswarte K, Hammad H, Lambrecht BN, Parker I, Cahalan MD. Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming. Nature Communications. 6: 6219. PMID 25653051 DOI: 10.1038/Ncomms7219 |
0.772 |
|
| 2015 |
Amcheslavsky A, Wood ML, Yeromin AV, Parker I, Freites JA, Tobias DJ, Cahalan MD. Molecular biophysics of Orai store-operated Ca2+ channels. Biophysical Journal. 108: 237-46. PMID 25606672 DOI: 10.1016/J.Bpj.2014.11.3473 |
0.766 |
|
| 2015 |
Dynes J, Amcheslavsky A, Cahalan M. Visualizing Calcium Influx through Single Orai1 Channels Biophysical Journal. 108: 178a. DOI: 10.1016/J.Bpj.2014.11.983 |
0.773 |
|
| 2014 |
Greenberg ML, Weinger JG, Matheu MP, Carbajal KS, Parker I, Macklin WB, Lane TE, Cahalan MD. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 111: E2349-55. PMID 24843159 DOI: 10.1073/Pnas.1406658111 |
0.712 |
|
| 2014 |
Amcheslavsky A, Safrina O, Cahalan MD. State-dependent block of Orai3 TM1 and TM3 cysteine mutants: insights into 2-APB activation. The Journal of General Physiology. 143: 621-31. PMID 24733836 DOI: 10.1085/Jgp.201411171 |
0.768 |
|
| 2014 |
Wood ML, Amcheslavsky A, Wong E, Freites JA, Cahalan MD, Tobias DJ. Atomistic Molecular Dynamics Simulations of Drosophila Orai in a Hydrated Lipid Bilayer Biophysical Journal. 106: 316a. DOI: 10.1016/J.Bpj.2013.11.1829 |
0.773 |
|
| 2014 |
Yeromin AV, Safrina O, Cahalan MD. Ph Dependence of Orai1 and Orai3 Store-Operated Current Biophysical Journal. 106: 315a. DOI: 10.1016/J.Bpj.2013.11.1824 |
0.407 |
|
| 2014 |
Matheu MP, Cahalan MD, Parker I. Intravital Imaging of the Immune System Advances in Intravital Microscopy: From Basic to Clinical Research. 81-103. DOI: 10.1007/978-94-017-9361-2_4 |
0.698 |
|
| 2013 |
Amcheslavsky A, Safrina O, Cahalan MD. Orai3 TM3 point mutation G158C alters kinetics of 2-APB-induced gating by disulfide bridge formation with TM2 C101. The Journal of General Physiology. 142: 405-12. PMID 24081982 DOI: 10.1085/Jgp.201311030 |
0.765 |
|
| 2013 |
Matheu MP, Teijaro JR, Walsh KB, Greenberg ML, Marsolais D, Parker I, Rosen H, Oldstone MB, Cahalan MD. Three phases of CD8 T cell response in the lung following H1N1 influenza infection and sphingosine 1 phosphate agonist therapy. Plos One. 8: e58033. PMID 23533579 DOI: 10.1371/Journal.Pone.0058033 |
0.761 |
|
| 2013 |
Greenberg ML, Yu Y, Leverrier S, Zhang SL, Parker I, Cahalan MD. Orai1 function is essential for T cell homing to lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 190: 3197-206. PMID 23455504 DOI: 10.4049/Jimmunol.1202212 |
0.675 |
|
| 2013 |
Perni S, Yeromin AV, Dynes JL, Cahalan MD, Franzini-Armstrong C. Visualization of STIM1 and Orai1 by Electron Microscopy Biophysical Journal. 104: 101a-102a. DOI: 10.1016/J.Bpj.2012.11.597 |
0.307 |
|
| 2012 |
Germain RN, Robey EA, Cahalan MD. A decade of imaging cellular motility and interaction dynamics in the immune system. Science (New York, N.Y.). 336: 1676-81. PMID 22745423 DOI: 10.1126/Science.1221063 |
0.415 |
|
| 2012 |
Matheu MP, Su Y, Greenberg ML, Blanc CA, Parker I, Scott DW, Cahalan MD. Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance. Proceedings of the National Academy of Sciences of the United States of America. 109: E1258-66. PMID 22511718 DOI: 10.1073/Pnas.1205150109 |
0.764 |
|
| 2012 |
Manolopoulou I, Matheu MP, Cahalan MD, West M, Kepler TB. Bayesian spatio-dynamic modeling in cell motility studies: Learning nonlinear taxic fields guiding the immune response Journal of the American Statistical Association. 107: 855-865. DOI: 10.1080/01621459.2012.655995 |
0.742 |
|
| 2011 |
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19072-7. PMID 22065776 DOI: 10.1073/Pnas.1116946108 |
0.38 |
|
| 2011 |
Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I. Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states. Proceedings of the National Academy of Sciences of the United States of America. 108: 17832-7. PMID 21987805 DOI: 10.1073/Pnas.1114814108 |
0.774 |
|
| 2011 |
Zhang SL, Yeromin AV, Hu J, Amcheslavsky A, Zheng H, Cahalan MD. Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91. Proceedings of the National Academy of Sciences of the United States of America. 108: 17838-43. PMID 21987804 DOI: 10.1073/Pnas.1114821108 |
0.798 |
|
| 2011 |
Khorshidi MA, Vanherberghen B, Kowalewski JM, Garrod KR, Lindström S, Andersson-Svahn H, Brismar H, Cahalan MD, Önfelt B. Analysis of transient migration behavior of natural killer cells imaged in situ and in vitro. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 770-8. PMID 21687858 DOI: 10.1039/C1Ib00007A |
0.797 |
|
| 2011 |
Matheu MP, Cahalan MD, Parker I. Immunoimaging: studying immune system dynamics using two-photon microscopy. Cold Spring Harbor Protocols. 2011: pdb.top99. PMID 21285279 DOI: 10.1101/Pdb.Top99 |
0.711 |
|
| 2011 |
Matheu MP, Cahalan MD, Parker I. In vivo lymph node imaging. Cold Spring Harbor Protocols. 2011: pdb.prot5568. PMID 21285268 DOI: 10.1101/Pdb.Prot5568 |
0.723 |
|
| 2011 |
Matheu MP, Cahalan MD, Parker I. In situ lymph node imaging. Cold Spring Harbor Protocols. 2011: pdb.prot5567. PMID 21285267 DOI: 10.1101/Pdb.Prot5567 |
0.721 |
|
| 2011 |
Matheu MP, Cahalan MD, Parker I. Induction of an immune response for imaging antigen-presenting cell/T-cell interactions. Cold Spring Harbor Protocols. 2011: pdb.prot5566. PMID 21285266 DOI: 10.1101/Pdb.Prot5566 |
0.766 |
|
| 2011 |
Matheu MP, Cahalan MD, Parker I. General approach to adoptive transfer and cell labeling for immunoimaging. Cold Spring Harbor Protocols. 2011: pdb.prot5565. PMID 21285265 DOI: 10.1101/Pdb.Prot5565 |
0.72 |
|
| 2011 |
Newton RH, Leverrier S, Srikanth S, Gwack Y, Cahalan MD, Walsh CM. Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation. Journal of Immunology (Baltimore, Md. : 1950). 186: 940-50. PMID 21148796 DOI: 10.4049/Jimmunol.1000942 |
0.437 |
|
| 2011 |
Demuro A, Penna A, Safrina O, Amcheslavsky A, Cahalan MD, Parker I. Subunit Stoichiometry of Human Orai1 and Orai3 in Closed and Open States Biophysical Journal. 100: 84a. DOI: 10.1016/J.Bpj.2010.12.665 |
0.775 |
|
| 2011 |
Zhang SL, Yeromin AV, Hu J, Amcheslavsky A, Zheng H, Cahalan MD. Activation of Orai1 Channels by Mutation of a Conserved Glycine Residue in TM1 Biophysical Journal. 100: 182a. DOI: 10.1016/J.Bpj.2010.12.1213 |
0.806 |
|
| 2010 |
Flach H, Rosenbaum M, Duchniewicz M, Kim S, Zhang SL, Cahalan MD, Mittler G, Grosschedl R. Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity. 33: 723-35. PMID 21093319 DOI: 10.1016/J.Immuni.2010.11.013 |
0.61 |
|
| 2010 |
Cahalan MD. Cell biology. How to STIMulate calcium channels. Science (New York, N.Y.). 330: 43-4. PMID 20929798 DOI: 10.1126/Science.1196348 |
0.476 |
|
| 2010 |
Sen D, Forrest L, Kepler TB, Parker I, Cahalan MD. Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. Proceedings of the National Academy of Sciences of the United States of America. 107: 8334-9. PMID 20404167 DOI: 10.1073/Pnas.0912817107 |
0.59 |
|
| 2010 |
Krummel MF, Cahalan MD. The immunological synapse: a dynamic platform for local signaling. Journal of Clinical Immunology. 30: 364-72. PMID 20390326 DOI: 10.1007/S10875-010-9393-6 |
0.321 |
|
| 2010 |
Garrod KR, Liu FC, Forrest LE, Parker I, Kang SM, Cahalan MD. NK cell patrolling and elimination of donor-derived dendritic cells favor indirect alloreactivity. Journal of Immunology (Baltimore, Md. : 1950). 184: 2329-36. PMID 20139277 DOI: 10.4049/Jimmunol.0902748 |
0.791 |
|
| 2010 |
Penna A, Kaake R, Safrina O, Forrest L, Yeromin A, Kaiser P, Huang L, Cahalan MD. Proteomics Analysis of the Drosophila CRAC Channel Complex in the Resting and Active State Biophysical Journal. 98: 97a. DOI: 10.1016/J.Bpj.2009.12.547 |
0.404 |
|
| 2010 |
Penna A, Zhang SL, Yeromin AV, Cahalan MD. Molecular mechanism of store-operated ca2+ signaling and crac channel activation mediated by stim & orai Handbook of Cell Signaling, 2/E. 1: 209-216. DOI: 10.1016/B978-0-12-374145-5.00031-0 |
0.551 |
|
| 2010 |
Garrod KR, Cahalan MD. Illuminating intranodal natural killer cell behaviour using two-photon microscopy Natural Killer Cells. 229-237. DOI: 10.1016/B978-0-12-370454-2.00017-X |
0.777 |
|
| 2009 |
Cahalan MD, Chandy KG. The functional network of ion channels in T lymphocytes. Immunological Reviews. 231: 59-87. PMID 19754890 DOI: 10.1111/J.1600-065X.2009.00816.X |
0.486 |
|
| 2009 |
Cahalan MD. STIMulating store-operated Ca(2+) entry. Nature Cell Biology. 11: 669-77. PMID 19488056 DOI: 10.1038/Ncb0609-669 |
0.391 |
|
| 2009 |
Yu Y, Keller SH, Remillard CV, Safrina O, Nicholson A, Zhang SL, Jiang W, Vangala N, Landsberg JW, Wang JY, Thistlethwaite PA, Channick RN, Robbins IM, Loyd JE, Ghofrani HA, ... ... Cahalan MD, et al. A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation. 119: 2313-22. PMID 19380626 DOI: 10.1161/Circulationaha.108.782458 |
0.524 |
|
| 2009 |
Penna A, Demuro A, Yeromin AV, Safrina O, Zhang SL, Parker I, Cahalan MD. Stim-regulated Assembly And Stoichiometry Of The CRAC Channel Subunit Orai Biophysical Journal. 96: 561a. DOI: 10.1016/J.Bpj.2008.12.3679 |
0.619 |
|
| 2009 |
Lioudyno MI, Sokolov Y, Kozak JA, Cahalan MD, Hall JE. Soluble β-amyloid oligomers alter biophysical properties of Kv1.3 channels Biophysical Journal. 96: 482a-483a. DOI: 10.1016/J.Bpj.2008.12.2488 |
0.504 |
|
| 2008 |
Garrod KR, Cahalan MD. Murine skin transplantation. Journal of Visualized Experiments : Jove. PMID 19066559 DOI: 10.3791/634 |
0.753 |
|
| 2008 |
Matheu MP, Sen D, Cahalan MD, Parker I. Generation of bone marrow derived murine dendritic cells for use in 2-photon imaging. Journal of Visualized Experiments : Jove. PMID 19066518 DOI: 10.3791/773 |
0.806 |
|
| 2008 |
Matheu MP, Beeton C, Garcia A, Chi V, Rangaraju S, Safrina O, Monaghan K, Uemura MI, Li D, Pal S, de la Maza LM, Monuki E, Flügel A, Pennington MW, Parker I, ... ... Cahalan MD, et al. Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity. 29: 602-14. PMID 18835197 DOI: 10.1016/J.Immuni.2008.07.015 |
0.782 |
|
| 2008 |
Sen D, Deerinck TJ, Ellisman MH, Parker I, Cahalan MD. Quantum dots for tracking dendritic cells and priming an immune response in vitro and in vivo. Plos One. 3: e3290. PMID 18820727 DOI: 10.1371/Journal.Pone.0003290 |
0.595 |
|
| 2008 |
Penna A, Demuro A, Yeromin AV, Zhang SL, Safrina O, Parker I, Cahalan MD. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature. 456: 116-20. PMID 18820677 DOI: 10.1038/Nature07338 |
0.639 |
|
| 2008 |
Zhang SL, Kozak JA, Jiang W, Yeromin AV, Chen J, Yu Y, Penna A, Shen W, Chi V, Cahalan MD. Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3. The Journal of Biological Chemistry. 283: 17662-71. PMID 18420579 DOI: 10.1074/Jbc.M801536200 |
0.683 |
|
| 2008 |
Lioudyno MI, Kozak JA, Penna A, Safrina O, Zhang SL, Sen D, Roos J, Stauderman KA, Cahalan MD. Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 2011-6. PMID 18250319 DOI: 10.1073/Pnas.0706122105 |
0.785 |
|
| 2008 |
Cahalan MD, Parker I. Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annual Review of Immunology. 26: 585-626. PMID 18173372 DOI: 10.1146/Annurev.Immunol.24.021605.090620 |
0.424 |
|
| 2007 |
Zhang S, Cahalan MD. Purifying plasmid DNA from bacterial colonies using the QIAGEN Miniprep Kit. Journal of Visualized Experiments : Jove. 247. PMID 18997895 DOI: 10.3791/247 |
0.478 |
|
| 2007 |
Matheu MP, Cahalan MD. Isolation of CD4+ T cells from mouse lymph nodes using Miltenyi MACS purification. Journal of Visualized Experiments : Jove. 409. PMID 18989449 DOI: 10.3791/409 |
0.756 |
|
| 2007 |
Matheu MP, Parker I, Cahalan MD. Dissection and 2-photon imaging of peripheral lymph nodes in mice. Journal of Visualized Experiments : Jove. 265. PMID 18989436 DOI: 10.3791/265 |
0.763 |
|
| 2007 |
Oak JS, Matheu MP, Parker I, Cahalan MD, Fruman DA. Lymphocyte cell motility: the twisting, turning tale of phosphoinositide 3-kinase. Biochemical Society Transactions. 35: 1109-13. PMID 17956290 DOI: 10.1042/Bst0351109 |
0.752 |
|
| 2007 |
Matheu MP, Deane JA, Parker I, Fruman DA, Cahalan MD. Class IA phosphoinositide 3-kinase modulates basal lymphocyte motility in the lymph node. Journal of Immunology (Baltimore, Md. : 1950). 179: 2261-9. PMID 17675487 DOI: 10.4049/Jimmunol.179.4.2261 |
0.765 |
|
| 2007 |
Wei SH, Safrina O, Yu Y, Garrod KR, Cahalan MD, Parker I. Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node. Journal of Immunology (Baltimore, Md. : 1950). 179: 1586-94. PMID 17641025 DOI: 10.4049/Jimmunol.179.3.1586 |
0.809 |
|
| 2007 |
Garrod KR, Wei SH, Parker I, Cahalan MD. Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets. Proceedings of the National Academy of Sciences of the United States of America. 104: 12081-6. PMID 17609379 DOI: 10.1073/Pnas.0702867104 |
0.802 |
|
| 2007 |
Cahalan MD, Zhang SL, Yeromin AV, Ohlsen K, Roos J, Stauderman KA. Molecular basis of the CRAC channel. Cell Calcium. 42: 133-44. PMID 17482674 DOI: 10.1016/J.Ceca.2007.03.002 |
0.65 |
|
| 2007 |
Uemura M, Beeton C, Matheu MP, Parker I, Pennington MW, Cahalan MD, Chandy KG. INHIBITING EFFECTOR MEMORY T CELLS WITH SHK(L5), A NOVEL PEPTIDE BLOCKER OF THE KV1.3 POTASSIUM CHANNEL. Journal of Investigative Medicine. 55: S78. DOI: 10.1097/00042871-200701010-00023 |
0.775 |
|
| 2006 |
Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O, Cahalan MD. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature. 443: 226-9. PMID 16921385 DOI: 10.1038/Nature05108 |
0.633 |
|
| 2006 |
Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nature Chemical Biology. 2: 434-41. PMID 16829954 DOI: 10.1038/Nchembio804 |
0.766 |
|
| 2006 |
Cahalan MD, Parker I. Imaging the choreography of lymphocyte trafficking and the immune response. Current Opinion in Immunology. 18: 476-82. PMID 16765574 DOI: 10.1016/J.Coi.2006.05.013 |
0.43 |
|
| 2006 |
Zhang SL, Yeromin AV, Zhang XH, Yu Y, Safrina O, Penna A, Roos J, Stauderman KA, Cahalan MD. Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 9357-62. PMID 16751269 DOI: 10.1073/Pnas.0603161103 |
0.603 |
|
| 2006 |
Cahalan MD, Gutman GA. The sense of place in the immune system. Nature Immunology. 7: 329-32. PMID 16550194 DOI: 10.1038/Ni0406-329 |
0.377 |
|
| 2005 |
Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I, Cahalan MD. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nature Immunology. 6: 1228-35. PMID 16273098 DOI: 10.1038/Ni1269 |
0.791 |
|
| 2005 |
Cahalan MD, Parker I. Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node. Seminars in Immunology. 17: 442-51. PMID 16263308 DOI: 10.1016/J.Smim.2005.09.001 |
0.44 |
|
| 2005 |
Kozak JA, Matsushita M, Nairn AC, Cahalan MD. Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels. The Journal of General Physiology. 126: 499-514. PMID 16260839 DOI: 10.1085/Jgp.200509324 |
0.543 |
|
| 2005 |
Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, Stauderman KA, Cahalan MD. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature. 437: 902-5. PMID 16208375 DOI: 10.1038/Nature04147 |
0.713 |
|
| 2005 |
Zinselmeyer BH, Dempster J, Gurney AM, Wokosin D, Miller M, Ho H, Millington OR, Smith KM, Rush CM, Parker I, Cahalan M, Brewer JM, Garside P. In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance Journal of Experimental Medicine. 201: 1815-1823. PMID 15928201 DOI: 10.1084/Jem.20050203 |
0.375 |
|
| 2005 |
Roos J, DiGregorio PJ, Yeromin AV, Ohlsen K, Lioudyno M, Zhang S, Safrina O, Kozak JA, Wagner SL, Cahalan MD, Veliçelebi G, Stauderman KA. STIM1, an essential and conserved component of store-operated Ca2+ channel function. The Journal of Cell Biology. 169: 435-45. PMID 15866891 DOI: 10.1083/Jcb.200502019 |
0.715 |
|
| 2005 |
Okada T, Miller MJ, Parker I, Krummel MF, Neighbors M, Hartley SB, O'Garra A, Cahalan MD, Cyster JG. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. Plos Biology. 3: e150. PMID 15857154 DOI: 10.1371/Journal.Pbio.0030150 |
0.414 |
|
| 2005 |
Matsushita M, Kozak JA, Shimizu Y, McLachlin DT, Yamaguchi H, Wei FY, Tomizawa K, Matsui H, Chait BT, Cahalan MD, Nairn AC. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. The Journal of Biological Chemistry. 280: 20793-803. PMID 15781465 DOI: 10.1074/Jbc.M413671200 |
0.541 |
|
| 2004 |
Miller MJ, Safrina O, Parker I, Cahalan MD. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. The Journal of Experimental Medicine. 200: 847-56. PMID 15466619 DOI: 10.1084/Jem.20041236 |
0.445 |
|
| 2004 |
Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. K+ channels as targets for specific immunomodulation. Trends in Pharmacological Sciences. 25: 280-9. PMID 15120495 DOI: 10.1016/J.Tips.2004.03.010 |
0.451 |
|
| 2004 |
Yeromin AV, Roos J, Stauderman KA, Cahalan MD. A store-operated calcium channel in Drosophila S2 cells. The Journal of General Physiology. 123: 167-82. PMID 14744989 DOI: 10.1085/Jgp.200308982 |
0.402 |
|
| 2004 |
Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proceedings of the National Academy of Sciences of the United States of America. 101: 998-1003. PMID 14722354 DOI: 10.1073/Pnas.0306407101 |
0.62 |
|
| 2004 |
Kolski-Andreaco A, Tomita H, Shakkottai VG, Gutman GA, Cahalan MD, Gargus JJ, Chandy KG. SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels. The Journal of Biological Chemistry. 279: 6893-904. PMID 14638680 DOI: 10.1074/Jbc.M311725200 |
0.397 |
|
| 2004 |
Akbari Y, Dagher N, Murphy MP, Kozak JA, Hitt B, Oddo S, Tseng B, Golde TE, Cahalan M, Leissring MA, M. LaFerla F. P1-206 Capacitative and non-capacitative Ca2+ entry modulate Aβ levels Neurobiology of Aging. 25: S154-S155. DOI: 10.1016/S0197-4580(04)80519-0 |
0.489 |
|
| 2003 |
Fomina AF, Deerinck TJ, Ellisman MH, Cahalan MD. Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells. Experimental Cell Research. 291: 150-66. PMID 14597416 DOI: 10.1016/S0014-4827(03)00372-0 |
0.404 |
|
| 2003 |
Wei SH, Parker I, Miller MJ, Cahalan MD. A stochastic view of lymphocyte motility and trafficking within the lymph node. Immunological Reviews. 195: 136-59. PMID 12969316 DOI: 10.1034/J.1600-065X.2003.00076.X |
0.581 |
|
| 2003 |
Cahalan MD, Parker I, Wei SH, Miller MJ. Real-time imaging of lymphocytes in vivo. Current Opinion in Immunology. 15: 372-7. PMID 12900266 DOI: 10.1016/S0952-7915(03)00079-7 |
0.584 |
|
| 2003 |
Tomita H, Shakkottai VG, Gutman GA, Sun G, Bunney WE, Cahalan MD, Chandy KG, Gargus JJ. Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia. Molecular Psychiatry. 8: 524-35, 460. PMID 12808432 DOI: 10.1038/Sj.Mp.4001271 |
0.341 |
|
| 2003 |
Kerschbaum HH, Kozak JA, Cahalan MD. Polyvalent cations as permeant probes of MIC and TRPM7 pores. Biophysical Journal. 84: 2293-305. PMID 12668438 DOI: 10.1016/S0006-3495(03)75035-8 |
0.565 |
|
| 2003 |
Miller MJ, Wei SH, Cahalan MD, Parker I. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy. Proceedings of the National Academy of Sciences of the United States of America. 100: 2604-9. PMID 12601158 DOI: 10.1073/Pnas.2628040100 |
0.621 |
|
| 2003 |
Kozak JA, Cahalan MD. MIC channels are inhibited by internal divalent cations but not ATP. Biophysical Journal. 84: 922-7. PMID 12547774 DOI: 10.1016/S0006-3495(03)74909-1 |
0.517 |
|
| 2003 |
Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes. The Journal of Biological Chemistry. 278: 9928-37. PMID 12511563 DOI: 10.1074/Jbc.M212868200 |
0.482 |
|
| 2003 |
Tomita H, Shakkottai VG, Gutman GA, Sun G, Bunney WE, Cahalan MD, Chandy KG, Gargus JJ. Erratum: Naturally occurring dominant-negative SK3 channel isoform Molecular Psychiatry. 8: 766-766. DOI: 10.1038/Sj.Mp.4001407 |
0.321 |
|
| 2003 |
Tomita H, Shakkottai VG, Gutman GA, Sun G, Bunney WE, Cahalan MD, Chandy KG, Gamrgus JJ. Naturally occurring dominant-negative SK3 channel isoform Molecular Psychiatry. 8: 460. DOI: 10.1038/Sj.Mp.4001358 |
0.385 |
|
| 2002 |
Cahalan MD, Parker I, Wei SH, Miller MJ. Two-photon tissue imaging: seeing the immune system in a fresh light. Nature Reviews. Immunology. 2: 872-80. PMID 12415310 DOI: 10.1038/Nri935 |
0.568 |
|
| 2002 |
Wei SH, Miller MJ, Cahalan MD, Parker I. Two-photon imaging in intact lymphoid tissue. Advances in Experimental Medicine and Biology. 512: 203-8. PMID 12405205 DOI: 10.1007/978-1-4615-0757-4_26 |
0.603 |
|
| 2002 |
Kozak JA, Kerschbaum HH, Cahalan MD. Distinct properties of CRAC and MIC channels in RBL cells. The Journal of General Physiology. 120: 221-35. PMID 12149283 DOI: 10.1085/Jgp.20028601 |
0.571 |
|
| 2002 |
Miller MJ, Wei SH, Parker I, Cahalan MD. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science (New York, N.Y.). 296: 1869-73. PMID 12016203 DOI: 10.1126/Science.1070051 |
0.613 |
|
| 2002 |
Cahalan MD. The ins and outs of polycystin-2 as a calcium release channel. Nature Cell Biology. 4: E56-7. PMID 11875447 DOI: 10.1038/Ncb0302-E56 |
0.32 |
|
| 2002 |
Ayabe T, Wulff H, Darmoul D, Cahalan MD, Chandy KG, Ouellette AJ. Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel. The Journal of Biological Chemistry. 277: 3793-800. PMID 11724775 DOI: 10.1074/Jbc.M107507200 |
0.426 |
|
| 2001 |
Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Béraud E. Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 98: 13942-7. PMID 11717451 DOI: 10.1073/Pnas.241497298 |
0.486 |
|
| 2001 |
Shakkottai VG, Regaya I, Wulff H, Fajloun Z, Tomita H, Fathallah M, Cahalan MD, Gargus JJ, Sabatier JM, Chandy KG. Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2. The Journal of Biological Chemistry. 276: 43145-51. PMID 11527975 DOI: 10.1074/Jbc.M106981200 |
0.36 |
|
| 2001 |
Cahalan MD, Wulff H, Chandy KG. Molecular properties and physiological roles of ion channels in the immune system. Journal of Clinical Immunology. 21: 235-52. PMID 11506193 DOI: 10.1023/A:1010958907271 |
0.45 |
|
| 2001 |
Wulff H, Gutman GA, Cahalan MD, Chandy KG. Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1. The Journal of Biological Chemistry. 276: 32040-5. PMID 11425865 DOI: 10.1074/Jbc.M105231200 |
0.378 |
|
| 2001 |
Miller MJ, Rauer H, Tomita H, Rauer H, Gargus JJ, Gutman GA, Cahalan MD, Chandy KG. Nuclear localization and dominant-negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia. The Journal of Biological Chemistry. 276: 27753-6. PMID 11395478 DOI: 10.1074/Jbc.C100221200 |
0.359 |
|
| 2001 |
Cahalan MD. Cell biology. Channels as enzymes. Nature. 411: 542-3. PMID 11385555 DOI: 10.1038/35079231 |
0.379 |
|
| 2001 |
Chandy KG, Cahalan M, Pennington M, Norton RS, Wulff H, Gutman GA. Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants. Toxicon : Official Journal of the International Society On Toxinology. 39: 1269-76. PMID 11384714 DOI: 10.1016/S0041-0101(01)00120-9 |
0.411 |
|
| 2001 |
Fanger CM, Rauer H, Neben AL, Miller MJ, Rauer H, Wulff H, Rosa JC, Ganellin CR, Chandy KG, Cahalan MD. Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels. The Journal of Biological Chemistry. 276: 12249-56. PMID 11278890 DOI: 10.1074/Jbc.M011342200 |
0.48 |
|
| 2000 |
Fomina AF, Fanger CM, Kozak JA, Cahalan MD. Single channel properties and regulated expression of Ca(2+) release-activated Ca(2+) (CRAC) channels in human T cells. The Journal of Cell Biology. 150: 1435-44. PMID 10995447 DOI: 10.1083/Jcb.150.6.1435 |
0.632 |
|
| 2000 |
Ghanshani S, Wulff H, Miller MJ, Rohm H, Neben A, Gutman GA, Cahalan MD, Chandy KG. Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. The Journal of Biological Chemistry. 275: 37137-49. PMID 10961988 DOI: 10.1074/Jbc.M003941200 |
0.506 |
|
| 2000 |
Wulff H, Miller MJ, Hansel W, Grissmer S, Cahalan MD, Chandy KG. Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant. Proceedings of the National Academy of Sciences of the United States of America. 97: 8151-6. PMID 10884437 DOI: 10.1073/Pnas.97.14.8151 |
0.371 |
|
| 2000 |
Wei X, Si MS, Imagawa DK, Ji P, Tromberg BJ, Cahalan MD. Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes. Cellular Immunology. 201: 6-13. PMID 10805968 DOI: 10.1006/Cimm.2000.1637 |
0.402 |
|
| 2000 |
Fanger CM, Neben AL, Cahalan MD. Differential Ca2+ influx, KCa channel activity, and Ca2+ clearance distinguish Th1 and Th2 lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 164: 1153-60. PMID 10640725 DOI: 10.4049/Jimmunol.164.3.1153 |
0.419 |
|
| 2000 |
Rauer H, Lanigan MD, Pennington MW, Aiyar J, Ghanshani S, Cahalan MD, Norton RS, Chandy KG. Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels. The Journal of Biological Chemistry. 275: 1201-8. PMID 10625664 DOI: 10.1074/Jbc.275.2.1201 |
0.422 |
|
| 2000 |
Ehring GR, Kerschbaum HH, Fanger CM, Eder C, Rauer H, Cahalan MD. Vanadate induces calcium signaling, Ca2+ release-activated Ca2+ channel activation, and gene expression in T lymphocytes and RBL-2H3 mast cells via thiol oxidation. Journal of Immunology (Baltimore, Md. : 1950). 164: 679-87. PMID 10623810 DOI: 10.4049/Jimmunol.164.2.679 |
0.423 |
|
| 1999 |
Rauer H, Pennington M, Cahalan M, Chandy KG. Structural conservation of the pores of calcium-activated and voltage-gated potassium channels determined by a sea anemone toxin. The Journal of Biological Chemistry. 274: 21885-92. PMID 10419508 DOI: 10.1074/Jbc.274.31.21885 |
0.404 |
|
| 1999 |
Wei X, Tromberg BJ, Cahalan MD. Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 8471-6. PMID 10411899 DOI: 10.1073/Pnas.96.15.8471 |
0.422 |
|
| 1999 |
Hanson DC, Nguyen A, Mather RJ, Rauer H, Koch K, Burgess LE, Rizzi JP, Donovan CB, Bruns MJ, Canniff PC, Cunningham AC, Verdries KA, Mena E, Kath JC, Gutman GA, ... Cahalan MD, et al. UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation. British Journal of Pharmacology. 126: 1707-16. PMID 10372812 DOI: 10.1038/Sj.Bjp.0702480 |
0.402 |
|
| 1999 |
Fanger CM, Ghanshani S, Logsdon NJ, Rauer H, Kalman K, Zhou J, Beckingham K, Chandy KG, Cahalan MD, Aiyar J. Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1. The Journal of Biological Chemistry. 274: 5746-54. PMID 10026195 DOI: 10.1074/Jbc.274.9.5746 |
0.458 |
|
| 1999 |
Kerschbaum HH, Cahalan MD. Single-channel recording of a store-operated Ca2+ channel in Jurkat T lymphocytes. Science (New York, N.Y.). 283: 836-9. PMID 9933165 DOI: 10.1126/Science.283.5403.836 |
0.462 |
|
| 1999 |
Andersen OS, Cahalan MD. The 52nd annual meeting and symposium of the Society of General Physiologists. Local calcium signaling in cell physiology. The Journal of General Physiology. 113: 153-9. PMID 9925813 DOI: 10.1085/Jgp.113.2.153 |
0.351 |
|
| 1998 |
Kalman K, Pennington MW, Lanigan MD, Nguyen A, Rauer H, Mahnir V, Paschetto K, Kem WR, Grissmer S, Gutman GA, Christian EP, Cahalan MD, Norton RS, Chandy KG. ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide. The Journal of Biological Chemistry. 273: 32697-707. PMID 9830012 DOI: 10.1074/Jbc.273.49.32697 |
0.39 |
|
| 1998 |
Ehring GR, Kerschbaum HH, Eder C, Neben AL, Fanger CM, Khoury RM, Negulescu PA, Cahalan MD. A nongenomic mechanism for progesterone-mediated immunosuppression: inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes. The Journal of Experimental Medicine. 188: 1593-602. PMID 9802971 |
0.383 |
|
| 1998 |
Kerschbaum HH, Cahalan MD. Monovalent permeability, rectification, and ionic block of store-operated calcium channels in Jurkat T lymphocytes. The Journal of General Physiology. 111: 521-37. PMID 9524136 DOI: 10.1085/Jgp.111.4.521 |
0.428 |
|
| 1998 |
Kalman K, Nguyen A, Tseng-Crank J, Dukes ID, Chandy G, Hustad CM, Copeland NG, Jenkins NA, Mohrenweiser H, Brandriff B, Cahalan M, Gutman GA, Chandy KG. Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7. The Journal of Biological Chemistry. 273: 5851-7. PMID 9488722 DOI: 10.1074/Jbc.273.10.5851 |
0.343 |
|
| 1998 |
Wei X, Krasieva TB, Zhang Z, Negulescu PA, Sun C, Berns MW, Cahalan MD, Tromberg BJ. Mapping the polarity and stimulus density requirements for T cell activation Proceedings of Spie. 3548: 11-16. DOI: 10.1117/12.317875 |
0.45 |
|
| 1997 |
Cahalan MD, Chandy KG. Ion channels in the immune system as targets for immunosuppression. Current Opinion in Biotechnology. 8: 749-56. PMID 9425667 DOI: 10.1016/S0958-1669(97)80130-9 |
0.451 |
|
| 1997 |
Ross PE, Ehring GR, Cahalan MD. Dynamics of ATP-induced calcium signaling in single mouse thymocytes. The Journal of Cell Biology. 138: 987-98. PMID 9281578 DOI: 10.1083/Jcb.138.5.987 |
0.341 |
|
| 1997 |
Kerschbaum HH, Negulescu PA, Cahalan MD. Ion channels, Ca2+ signaling, and reporter gene expression in antigen-specific mouse T cells. Journal of Immunology (Baltimore, Md. : 1950). 159: 1628-38. PMID 9257822 |
0.358 |
|
| 1997 |
Allen DH, Lepple-Wienhues A, Cahalan MD. Ion channel phenotype of melanoma cell lines. The Journal of Membrane Biology. 155: 27-34. PMID 9002422 DOI: 10.1007/S002329900155 |
0.461 |
|
| 1997 |
Garber SS, Cahalan MD. Volume-Regulated Anion Channels and the Control of a Simple Cell Behavior Cellular Physiology and Biochemistry. 7: 229-241. DOI: 10.1159/000154877 |
0.423 |
|
| 1997 |
Lepple-Wienhues A, Cahalan MD. A Mysterious Channel: Properties of the Capacitive Ca2+ Channel in Lymphocytes Cellular Physiology and Biochemistry. 7: 219-228. DOI: 10.1159/000154876 |
0.428 |
|
| 1996 |
Nguyen A, Kath JC, Hanson DC, Biggers MS, Canniff PC, Donovan CB, Mather RJ, Bruns MJ, Rauer H, Aiyar J, Lepple-Wienhues A, Gutman GA, Grissmer S, Cahalan MD, Chandy KG. Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation. Molecular Pharmacology. 50: 1672-9. PMID 8967992 |
0.322 |
|
| 1996 |
Lepple-Wienhues A, Cahalan MD. Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells. Biophysical Journal. 71: 787-94. PMID 8842217 DOI: 10.1016/S0006-3495(96)79278-0 |
0.407 |
|
| 1996 |
Negulescu PA, Krasieva TB, Khan A, Kerschbaum HH, Cahalan MD. Polarity of T cell shape, motility, and sensitivity to antigen. Immunity. 4: 421-30. PMID 8630728 DOI: 10.1016/S1074-7613(00)80409-4 |
0.454 |
|
| 1995 |
Ross PE, Cahalan MD. Ca2+ influx pathways mediated by swelling or stores depletion in mouse thymocytes. The Journal of General Physiology. 106: 415-44. PMID 8786341 DOI: 10.1085/Jgp.106.3.415 |
0.374 |
|
| 1995 |
Lewis RS, Cahalan MD. Potassium and calcium channels in lymphocytes. Annual Review of Immunology. 13: 623-53. PMID 7612237 DOI: 10.1146/Annurev.Iy.13.040195.003203 |
0.612 |
|
| 1995 |
Verheugen JA, Vijverberg HP, Oortgiesen M, Cahalan MD. Voltage-gated and Ca(2+)-activated K+ channels in intact human T lymphocytes. Noninvasive measurements of membrane currents, membrane potential, and intracellular calcium. The Journal of General Physiology. 105: 765-94. PMID 7561743 DOI: 10.1085/Jgp.105.6.765 |
0.44 |
|
| 1994 |
Negulescu PA, Shastri N, Cahalan MD. Intracellular calcium dependence of gene expression in single T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 91: 2873-7. PMID 8146203 DOI: 10.1073/Pnas.91.7.2873 |
0.432 |
|
| 1994 |
Ross PE, Garber SS, Cahalan MD. Membrane chloride conductance and capacitance in Jurkat T lymphocytes during osmotic swelling. Biophysical Journal. 66: 169-78. PMID 8130336 DOI: 10.1016/S0006-3495(94)80754-4 |
0.372 |
|
| 1994 |
Ehring GR, Osipchuk YV, Cahalan MD. Swelling-activated chloride channels in multidrug-sensitive and -resistant cells. The Journal of General Physiology. 104: 1129-61. PMID 7699367 DOI: 10.1085/Jgp.104.6.1129 |
0.413 |
|
| 1994 |
Cahalan MD, Lewis RS. Regulation of chloride channels in lymphocytes Current Topics in Membranes. 42: 103-129. DOI: 10.1016/S0070-2161(08)60820-5 |
0.568 |
|
| 1993 |
Lewis RS, Ross PE, Cahalan MD. Chloride channels activated by osmotic stress in T lymphocytes. The Journal of General Physiology. 101: 801-26. PMID 7687269 DOI: 10.1085/Jgp.101.6.801 |
0.572 |
|
| 1993 |
Grissmer S, Nguyen AN, Cahalan MD. Calcium-activated potassium channels in resting and activated human T lymphocytes. Expression levels, calcium dependence, ion selectivity, and pharmacology. The Journal of General Physiology. 102: 601-30. PMID 7505804 DOI: 10.1085/Jgp.102.4.601 |
0.451 |
|
| 1992 |
Grissmer S, Ghanshani S, Dethlefs B, McPherson JD, Wasmuth JJ, Gutman GA, Cahalan MD, Chandy KG. The Shaw-related potassium channel gene, Kv3.1, on human chromosome 11, encodes the type l K+ channel in T cells. The Journal of Biological Chemistry. 267: 20971-9. PMID 1400413 |
0.306 |
|
| 1992 |
Osipchuk Y, Cahalan M. Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells. Nature. 359: 241-244. PMID 1388246 DOI: 10.1038/359241A0 |
0.433 |
|
| 1992 |
Cahalan M, Neher E. Patch clamp techniques: an overview. Methods in Enzymology. 207: 3-14. PMID 1382186 DOI: 10.1016/0076-6879(92)07003-7 |
0.395 |
|
| 1992 |
Grissmer S, Lewis RS, Cahalan MD. Ca(2+)-activated K+ channels in human leukemic T cells. The Journal of General Physiology. 99: 63-84. PMID 1371308 DOI: 10.1085/Jgp.99.1.63 |
0.601 |
|
| 1991 |
Cahalan MD, Chandy KG, Grissmer S. Chapter 11 Potassium Channels in Development, Activation, and Disease in T Lymphocytes Current Topics in Membranes. 39: 357-394. DOI: 10.1016/S0070-2161(08)60809-6 |
0.503 |
|
| 1990 |
Grissmer S, Dethlefs B, Wasmuth JJ, Goldin AL, Gutman GA, Cahalan MD, Chandy KG. Expression and chromosomal localization of a lymphocyte K+ channel gene. Proceedings of the National Academy of Sciences of the United States of America. 87: 9411-5. PMID 2251283 DOI: 10.1073/Pnas.87.23.9411 |
0.401 |
|
| 1990 |
McCloskey MA, Cahalan MD. G protein control of potassium channel activity in a mast cell line. The Journal of General Physiology. 95: 205-27. PMID 2106571 DOI: 10.1085/Jgp.95.2.205 |
0.403 |
|
| 1990 |
Chandy KG, Cahalan MD, Grissmer S. Autoimmune diseases linked to abnormal K+ channel expression in double-negative CD4-CD8- T cells. European Journal of Immunology. 20: 747-51. PMID 1971790 DOI: 10.1002/Eji.1830200406 |
0.426 |
|
| 1990 |
Cahalan MD, Lewis RS. Functional roles of ion channels in lymphocytes. Seminars in Immunology. 2: 107-17. PMID 1717052 |
0.556 |
|
| 1990 |
Lewis RS, Cahalan MD. Ion channels and signal transduction in lymphocytes. Annual Review of Physiology. 52: 415-30. PMID 1691906 DOI: 10.1146/Annurev.Ph.52.030190.002215 |
0.604 |
|
| 1989 |
Sutro JB, Vayuvegula BS, Gupta S, Cahalan MD. Voltage-sensitive ion channels in human B lymphocytes. Advances in Experimental Medicine and Biology. 254: 113-22. PMID 2816543 DOI: 10.1007/978-1-4757-5803-0_14 |
0.414 |
|
| 1989 |
Grissmer S, Cahalan MD. Divalent ion trapping inside potassium channels of human T lymphocytes. The Journal of General Physiology. 93: 609-30. PMID 2786551 DOI: 10.1085/Jgp.93.4.609 |
0.43 |
|
| 1989 |
Grissmer S, Cahalan M. TEA prevents inactivation while blocking open K+ channels in human T lymphocytes. Biophysical Journal. 55: 203-6. PMID 2784693 DOI: 10.1016/S0006-3495(89)82793-6 |
0.319 |
|
| 1989 |
Lewis RS, Cahalan MD. Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells. Cell Regulation. 1: 99-112. PMID 2519622 DOI: 10.1091/Mbc.1.1.99 |
0.586 |
|
| 1989 |
Sands SB, Lewis RS, Cahalan MD. Charybdotoxin blocks voltage-gated K+ channels in human and murine T lymphocytes. The Journal of General Physiology. 93: 1061-74. PMID 2475579 DOI: 10.1085/Jgp.93.6.1061 |
0.58 |
|
| 1988 |
Cahalan MD, Lewis RS. Role of potassium and chloride channels in volume regulation by T lymphocytes. Society of General Physiologists Series. 43: 281-301. PMID 2479106 |
0.5 |
|
| 1988 |
Lewis RS, Cahalan MD. The plasticity of ion channels: parallels between the nervous and immune systems. Trends in Neurosciences. 11: 214-8. PMID 2471326 DOI: 10.1016/0166-2236(88)90129-4 |
0.629 |
|
| 1988 |
Lewis RS, Cahalan MD. Subset-specific expression of potassium channels in developing murine T lymphocytes. Science (New York, N.Y.). 239: 771-5. PMID 2448877 DOI: 10.1126/Science.2448877 |
0.537 |
|
| 1987 |
Cahalan MD, Chandy KG, DeCoursey TE, Gupta S, Lewis RS, Sutro JB. Ion channels in T lymphocytes. Advances in Experimental Medicine and Biology. 213: 85-101. PMID 2442978 DOI: 10.1007/978-1-4684-5323-2_9 |
0.55 |
|
| 1987 |
Decoursey TE, Chandy KG, Gupta S, Cahalan MD. Mitogen induction of ion channels in murine T lymphocytes. The Journal of General Physiology. 89: 405-20. PMID 2435845 DOI: 10.1085/Jgp.89.3.405 |
0.451 |
|
| 1987 |
Decoursey TE, Chandy KG, Gupta S, Cahalan MD. Two types of potassium channels in murine T lymphocytes. The Journal of General Physiology. 89: 379-404. PMID 2435844 DOI: 10.1085/Jgp.89.3.379 |
0.403 |
|
| 1986 |
Chandy KG, DeCoursey TE, Fischbach M, Talal N, Cahalan MD, Gupta S. Altered K+ channel expression in abnormal T lymphocytes from mice with the lpr gene mutation. Science (New York, N.Y.). 233: 1197-200. PMID 2426784 DOI: 10.1126/science.2426784 |
0.318 |
|
| 1985 |
Cahalan MD, Chandy KG, DeCoursey TE, Gupta S. A voltage-gated potassium channel in human T lymphocytes. The Journal of Physiology. 358: 197-237. PMID 2580081 DOI: 10.1113/Jphysiol.1985.Sp015548 |
0.33 |
|
| 1985 |
Chandy KG, DeCoursey TE, Cahalan MD, Gupta S. Ion channels in lymphocytes. Journal of Clinical Immunology. 5: 1-6. PMID 2579969 DOI: 10.1007/Bf00915161 |
0.418 |
|
| 1985 |
Pappone PA, Cahalan MD. Demyelination as a test for a mobile Na channel modulator in frog node of Ranvier. Biophysical Journal. 47: 217-23. PMID 2579686 DOI: 10.1016/S0006-3495(85)83894-7 |
0.359 |
|
| 1985 |
DeCoursey TE, Chandy KG, Gupta S, Cahalan MD. Voltage-dependent ion channels in T-lymphocytes. Journal of Neuroimmunology. 10: 71-95. PMID 2414315 DOI: 10.1016/0165-5728(85)90035-9 |
0.479 |
|
| 1985 |
CHANDY K, SHARMA B, DECOURSEY T, CAHALAN M, GUPTA S. 307 K channel requirement for human T-cell mediated cytotoxicity Journal of Allergy and Clinical Immunology. 75: 181. DOI: 10.1016/0091-6749(85)90442-7 |
0.418 |
|
| 1984 |
Pappone PA, Cahalan MD. Chemical Modification of Potassium Channels in Myelinated Nerve Fibers: Treatment With TNBS or High pH Causes Resistance to Block by 4-Aminopyridine. Biophysical Journal. 45: 62-4. PMID 19431567 DOI: 10.1016/S0006-3495(84)84109-0 |
0.395 |
|
| 1984 |
DeCoursey TE, Chandy KG, Gupta S, Cahalan MD. Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis? Nature. 307: 465-8. PMID 6320007 DOI: 10.1038/307465A0 |
0.43 |
|
| 1984 |
Chandy KG, DeCoursey TE, Cahalan MD, McLaughlin C, Gupta S. Voltage-gated potassium channels are required for human T lymphocyte activation. The Journal of Experimental Medicine. 160: 369-85. PMID 6088661 DOI: 10.1084/Jem.160.2.369 |
0.403 |
|
| 1983 |
Cahalan MD, Pappone PA. Chemical modification of potassium channel gating in frog myelinated nerve by trinitrobenzene sulphonic acid. The Journal of Physiology. 342: 119-43. PMID 6313907 DOI: 10.1113/Jphysiol.1983.Sp014843 |
0.325 |
|
| 1982 |
Cahalan MD, Hall J. Alamethicin channels incorporated into frog node of ranvier: calcium-induced inactivation and membrane surface charges. The Journal of General Physiology. 79: 411-36. PMID 6281358 DOI: 10.1085/Jgp.79.3.411 |
0.353 |
|
| 1980 |
Begenisich TB, Cahalan MD. Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations. The Journal of Physiology. 307: 243-57. PMID 6259335 DOI: 10.1113/Jphysiol.1980.Sp013433 |
0.319 |
|
| 1980 |
Begenisich TB, Cahalan MD. Sodium channel permeation in squid axons. I: Reversal potential experiments. The Journal of Physiology. 307: 217-42. PMID 6259334 DOI: 10.1113/Jphysiol.1980.Sp013432 |
0.304 |
|
| 1979 |
Cahalan MD, Almers W. Block of sodium conductance and gating current in squid giant axons poisoned with quaternary strychnine. Biophysical Journal. 27: 57-73. PMID 233569 DOI: 10.1016/S0006-3495(79)85202-9 |
0.337 |
|
| 1979 |
Cahalan MD, Almers W. Interactions between quaternary lidocaine, the sodium channel gates, and tetrodotoxin. Biophysical Journal. 27: 39-55. PMID 233568 DOI: 10.1016/S0006-3495(79)85201-7 |
0.359 |
|
| 1976 |
Cahalan M, Begenisich T. Sodium channel selectivity. Dependence on internal permeant ion concentration. The Journal of General Physiology. 68: 111-25. PMID 956766 DOI: 10.1085/Jgp.68.2.111 |
0.304 |
|
| 1975 |
Cahalan MD. Modification of sodium channel gating in frog myelinated nerve fibres by Centruroides sculpturatus scorpion venom. The Journal of Physiology. 244: 511-34. PMID 1079869 DOI: 10.1113/Jphysiol.1975.Sp010810 |
0.356 |
|
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