Charles G. Eberhart, MD PhD - Publications

Affiliations: 
Pathology Johns Hopkins University, Baltimore, MD 
Area:
pathology and molecular biology of pediatric brain tumors
Website:
http://pds17.pathology.jhmi.edu/N/n.web?EP=N&URL=/MCGI/SEND^WEBUTLTY(1058)/1543522402

326 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lee SC, Alaali L, Kwon H, Rigi M, Eberhart CG. Cordycepin (3'-Deoxyadenosine) Suppresses Heat Shock Protein 90 Function and Targets Tumor Growth in an Adenosine Deaminase-Dependent Manner. Cancers. 14. PMID 35804893 DOI: 10.3390/cancers14133122  0.324
2022 Pham K, Hanaford AR, Poore BA, Maxwell MJ, Sweeney H, Parthasarathy A, Alt J, Rais R, Slusher BS, Eberhart CG, Raabe EH. Comprehensive Metabolic Profiling of MYC-Amplified Medulloblastoma Tumors Reveals Key Dependencies on Amino Acid, Tricarboxylic Acid and Hexosamine Pathways. Cancers. 14. PMID 35267619 DOI: 10.3390/cancers14051311  0.301
2021 Zhan D, Ma D, Wei S, Lal B, Fu Y, Eberhart C, Laterra J, Ying M, Li Y, Meeker A, Lopez-Bertoni H, Xia S. Monoallelic IDH1 R132H mutation mediates glioma cell response to anti-cancer therapies via induction of senescence. Molecular Cancer Research : McR. PMID 34348994 DOI: 10.1158/1541-7786.MCR-21-0284  0.355
2021 Ma D, Zhan D, Fu Y, Wei S, Lal B, Wang J, Li Y, Lopez-Bertoni H, Yalcin F, Dzaye O, Eberhart CG, Laterra J, Wilson MA, Ying M, Xia S. Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1. Cancer Letters. PMID 34098063 DOI: 10.1016/j.canlet.2021.05.038  0.325
2021 Nakata S, Yuan M, Rubens JA, Kahlert UD, Maciaczyk J, Raabe EH, Eberhart CG. BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets. International Journal of Molecular Sciences. 22. PMID 33920124 DOI: 10.3390/ijms22083913  0.357
2021 Xue Y, Fu Y, Zhao F, Gui G, Li Y, Rivero-Hinojosa S, Liu G, Li Y, Xia S, Eberhart CG, Ying M. Frondoside A Inhibits a MYC-driven Medulloblastoma Model Derived from Human Induced Pluripotent Stem Cells. Molecular Cancer Therapeutics. PMID 33722850 DOI: 10.1158/1535-7163.MCT-20-0603  0.349
2021 Maynard R, Poore B, Hanaford AR, Pham K, James M, Alt J, Park Y, Slusher BS, Tamayo P, Mesirov J, Archer TC, Pomeroy S, Eberhart CG, Raabe EH. TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma. Cancer Letters. PMID 33571541 DOI: 10.1016/j.canlet.2021.02.001  0.358
2020 Yuan M, White D, Resar L, Bar E, Groves M, Cohen A, Jackson E, Bynum J, Rubens J, Mumm J, Chen L, Jiang L, Raabe E, Rodriguez F, Eberhart CG. Conditional reprograming culture conditions facilitate growth of lower grade glioma models. Neuro-Oncology. PMID 33258947 DOI: 10.1093/neuonc/noaa263  0.699
2020 Shinde V, Hu N, Mahale A, Maiti G, Daoud Y, Eberhart CG, Maktabi A, Jun AS, Al-Swailem SA, Chakravarti S. RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses. Scientific Reports. 10: 9907. PMID 32555404 DOI: 10.1038/S41598-020-66735-X  0.304
2020 Alkatan HM, Alsalamah AK, Almizel A, Alshomar KM, Maktabi AM, ElKhamary SM, Eberhart CG, Iuliano A, Lanni V, Strianese D. Orbital solitary fibrous tumors: a multi-centered histopathological and immunohistochemical analysis with radiological description. Annals of Saudi Medicine. 40: 227-233. PMID 32493043 DOI: 10.5144/0256-4947.2020.227  0.398
2020 Shahab S, Rubens J, Kaur H, Sweeney H, Eberhart CG, Raabe EH. MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors. Journal of Neuropathology and Experimental Neurology. PMID 32472116 DOI: 10.1093/Jnen/Nlaa042  0.446
2020 Lazo de la Vega L, Bick N, Hu K, Rahrig SE, Silva CD, Matayoshi S, Picciarelli P, Wang X, Sugar A, Soong HK, Mian SI, Robinson DR, Chinnaiyan AM, Demirci H, Daniels AB, ... ... Eberhart CG, et al. Invasive squamous cell carcinomas and precursor lesions on UV-exposed epithelia demonstrate concordant genomic complexity in driver genes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32461624 DOI: 10.1038/S41379-020-0571-7  0.346
2020 Eberhart CG, Bar EE. Spatial enrichment of cellular states in glioblastoma. Acta Neuropathologica. PMID 32449056 DOI: 10.1007/S00401-020-02165-3  0.674
2020 Negron K, Zhu C, Chen SW, Shahab S, Rao D, Raabe EH, Eberhart CG, Hanes J, Suk JS. Non-adhesive and highly stable biodegradable nanoparticles that provide widespread and safe transgene expression in orthotopic brain tumors. Drug Delivery and Translational Research. PMID 32323162 DOI: 10.1007/S13346-020-00759-8  0.367
2020 Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, et al. cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathology (Zurich, Switzerland). PMID 32307792 DOI: 10.1111/Bpa.12832  0.352
2020 Rubens J, Eberhart CG. SWI/SNF complex differences promote cellular heterogeneity in rhabdoid tumors. Neuro-Oncology. PMID 32227229 DOI: 10.1093/Neuonc/Noaa081  0.363
2020 Nakata S, Price A, Eberhart C, Morris M. Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration. Journal of Neuropathology and Experimental Neurology. PMID 32181806 DOI: 10.1093/Jnen/Nlaa013  0.368
2020 Yao M, Ventura PB, Jiang Y, Rodriguez FJ, Wang L, Perry JSA, Yang Y, Wahl K, Crittenden RB, Bennett ML, Qi L, Gong CC, Li XN, Barres BA, Bender TP, ... ... Eberhart CG, et al. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth. Cell. PMID 31983537 DOI: 10.1016/J.Cell.2019.12.024  0.41
2020 Kaur H, Guo H, White D, Green P, Hector AM, Akhtarkhavari S, Bhargava A, Shah S, Eberhart CG, Mumm J, Raabe EH. Abstract A38: Validation of potential therapies for treatment of fatal pediatric brain tumors DIPG and AT/RT using a novel rapid intracranial model in zebrafish Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A38  0.456
2020 Parkhurst A, Wang S, Kaur H, Arnold A, Eberhart C, Raabe E, Rubens J. Abstract 6226: Sapanisertib interferes with the NRF2-mediated stress response to synergize with Obatoclax and extend AT/RT survival Cancer Research. 80: 6226-6226. DOI: 10.1158/1538-7445.Am2020-6226  0.394
2020 Guo H, Kaur H, Eberhart CG, Raabe EH. Abstract 4943: The stem cell factor LIN28B regulates proliferation and apoptosis in diffuse intrinsic pontine glioma Cancer Research. 80: 4943-4943. DOI: 10.1158/1538-7445.Am2020-4943  0.487
2020 Parkhurst A, Park Y, Arnold A, Koldobskiy M, Eberhart C, Raabe E, Rubens J. Abstract 3904: The novel combination of PAC-1 and ONC201 circumvent H3K27M-driven pro-survival gene expression to induce DIPG cell death Tumor Biology. DOI: 10.1158/1538-7445.Am2020-3904  0.322
2019 Arnold A, Yuan M, Price A, Harris L, Eberhart CG, Raabe EH. Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity. Neuro-Oncology. PMID 31841591 DOI: 10.1093/Neuonc/Noz230  0.365
2019 Zhang M, Iyer RR, Azad TD, Wang Q, Garzon-Muvdi T, Wang J, Liu A, Burger P, Eberhart C, Rodriguez FJ, Sciubba DM, Wolinsky JP, Gokaslan Z, Groves ML, Jallo GI, et al. Genomic Landscape of Intramedullary Spinal Cord Gliomas. Scientific Reports. 9: 18722. PMID 31822682 DOI: 10.1038/S41598-019-54286-9  0.351
2019 Martin AM, Bell WR, Yuan M, Harris L, Poore B, Arnold A, Engle EL, Asnaghi L, Lim M, Raabe EH, Eberhart CG. PD-L1 Expression in Pediatric Low-Grade Gliomas Is Independent of BRAF V600E Mutational Status. Journal of Neuropathology and Experimental Neurology. PMID 31819973 DOI: 10.1093/Jnen/Nlz119  0.308
2019 Han D, Serra R, Gorelick N, Fatima U, Eberhart CG, Brem H, Tyler B, Steckl AJ. Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor. Scientific Reports. 9: 17936. PMID 31784666 DOI: 10.1038/S41598-019-54283-Y  0.316
2019 Shinde V, Hu N, Renuse S, Mahale A, Pandey A, Eberhart C, Stone D, Al-Swailem SA, Maktabi A, Chakravarti S. Mapping Keratoconus Molecular Substrates by Multiplexed High-Resolution Proteomics of Unpooled Corneas. Omics : a Journal of Integrative Biology. PMID 31651220 DOI: 10.1089/Omi.2019.0143  0.305
2019 Asnaghi L, White DT, Yoon L, Price A, Lee GY, Sahoo A, Mumm JS, Eberhart CG. Downregulation of Nodal inhibits metastatic progression in retinoblastoma. Acta Neuropathologica Communications. 7: 137. PMID 31451106 DOI: 10.1186/S40478-019-0785-4  0.418
2019 Hanaford AR, Alt J, Rais R, Wang SZ, Kaur H, Thorek DLJ, Eberhart CG, Slusher BS, Martin AM, Raabe EH. Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma. Translational Oncology. 12: 1314-1322. PMID 31340195 DOI: 10.1016/J.Tranon.2019.05.013  0.455
2019 Wang SZ, Poore B, Alt J, Price A, Allen SJ, Hanaford AR, Kaur H, Orr BA, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31300448 DOI: 10.1158/1078-0432.Ccr-19-0189  0.44
2019 Martínez H, Nagurney M, Wang ZX, Eberhart CG, Heaphy CM, Curtis MT, Rodriguez FJ. ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation. Journal of Neuropathology and Experimental Neurology. PMID 31225581 DOI: 10.1093/Jnen/Nlz050  0.392
2019 Eberhart CG. A fox with many faces: FOXR2 and embryonal brain tumors. Neuro-Oncology. PMID 31149715 DOI: 10.1093/Neuonc/Noz102  0.354
2019 Yates JR, Mines MJ, Subramanian PS, Rivera-Michlig R, Cummings TJ, Eberhart CG. Periocular Histiocytoid Carcinoma: Potential Diagnostic Challenges. Ocular Oncology and Pathology. 5: 94-101. PMID 30976586 DOI: 10.1159/000490250  0.314
2019 Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, ... ... Eberhart CG, et al. Myc and loss of p53 cooperate to drive formation of choroid plexus carcinoma. Cancer Research. PMID 30885981 DOI: 10.1158/0008-5472.Can-18-2565  0.439
2019 Tao R, Murad N, Xu Z, Zhang P, Okonechnikov K, Kool M, Rivero-Hinojosa S, Lazarski C, Zheng P, Liu Y, Eberhart CG, Rood BR, Packer R, Pei Y. MYC drives Group 3 medulloblastoma through transformation of Sox2+ astrocyte progenitor cells. Cancer Research. PMID 30862721 DOI: 10.1158/0008-5472.Can-18-1787  0.461
2019 Schlein LJ, Fadl-Alla B, Pondenis HC, Lezmi S, Eberhart CG, LeBlanc AK, Dickinson PJ, Hergenrother PJ, Fan TM. Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers. Frontiers in Oncology. 9: 96. PMID 30859090 DOI: 10.3389/Fonc.2019.00096  0.387
2019 Beckmann PJ, Larson JD, Larsson AT, Ostergaard JP, Wagner S, Rahrmann EP, Shamsan GA, Otto GM, Williams RL, Wang J, Lee C, Tschida BR, Das P, Dubuc AM, Moriarity BS, ... ... Eberhart CG, et al. Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors. Cancer Research. PMID 30674530 DOI: 10.1158/0008-5472.Can-18-1261  0.402
2019 Natsumeda M, Liu Y, Nakata S, Miyahara H, Hanaford A, Ahsan S, Stearns D, Skuli N, Kahlert UD, Raabe EH, Rodriguez FJ, Eberhart CG. Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 30632221 DOI: 10.1111/Neup.12534  0.374
2019 Wang SZ, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe EH, Rubens JH. Abstract 5267: Unbiased metabolic profiling of atypical teratoid/rhabdoid tumors predicts sensitivity to the glutamine metabolic inhibitor 6-diazo-5-oxo-L-norleucine Cancer Research. 79: 5267-5267. DOI: 10.1158/1538-7445.Sabcs18-5267  0.411
2019 Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. Abstract 3108: Inhibition of the mTOR and MAPK pathways suppresses growth, induces apoptosis, and decreases vascularity in pediatric low grade glioma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3108  0.336
2019 Kaur H, Guo H, Green P, Akhtarkhavari S, Shah S, Eberhart CG, Raabe EH. Abstract 2888: Targeting the fatal pediatric brain tumors AT/RT and DIPG with the DNA binding agent quinacrine Cancer Research. 79: 2888-2888. DOI: 10.1158/1538-7445.Sabcs18-2888  0.455
2019 Shahab S, Rubens J, Eberhart C, Raabe E. Abstract 3120: The novel MEK inhibitor binimetinib decreases cell growth and induces apoptosis in AT/RT Cancer Research. 79: 3120-3120. DOI: 10.1158/1538-7445.Am2019-3120  0.461
2019 Azad TD, Zhang M, Iyer R, Wang Q, Garzon-Muvdi T, Wang J, Liu A, Burger PC, Eberhart CG, Rodriguez FJ, Sciubba DM, Wolinsky J, Gokaslan ZL. Genomic Landscape of Intramedullary Spinal Cord Tumors Suggests Distinct Genetic Origins Compared to Intracranial Histopathologic Counterparts Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_332  0.361
2019 Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. PDTM-18. COMBINED SUPPRESSION OF THE mTOR AND MAPK PATHWAYS INHIBITS GROWTH, DECREASES VASCULARITY AND INDUCES APOPTOSIS OR SENESCENCE IN PEDIATRIC LOW GRADE GLIOMA Neuro-Oncology. 21: vi191-vi191. DOI: 10.1093/Neuonc/Noz175.794  0.442
2019 Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. LGG-15. COMBINED SUPPRESSION OF THE MTOR AND MAPK PATHWAYS INHIBITS CELL PROLIFERATION AND DECREASES VASCULARITY IN PEDIATRIC LOW GRADE GLIOMA Neuro-Oncology. 21: ii102-ii102. DOI: 10.1093/Neuonc/Noz036.158  0.387
2019 Kaur H, Guo H, Akhtarkhavari S, Eberhart C, Raabe E. HGG-25. TARGETING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND HIGH GRADE GLIOMAS INHIBITS PROLIFERATION, INVASION AND TUMORIGENICITY Neuro-Oncology. 21: ii92-ii92. DOI: 10.1093/Neuonc/Noz036.119  0.344
2019 Shahab S, Rubens J, Eberhart C, Raabe E. ATRT-12. BINIMETINIB SUPPRESSES THE GROWTH OF ATYPICAL TERATOID/RHABDOID TUMOR CELLS AND INDUCES APOPOTOSIS Neuro-Oncology. 21: ii65-ii65. DOI: 10.1093/Neuonc/Noz036.011  0.43
2019 Wang S, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe E, Rubens J. ATRT-04. UNBIASED METABOLIC PROFILING OF ATYPICAL TERATOID/RHABDOID TUMORS PREDICTS SENSITIVITY TO GLUTAMINE METABOLIC INHIBITORS Neuro-Oncology. 21: ii63-ii63. DOI: 10.1093/Neuonc/Noz036.003  0.301
2018 Asnaghi L, White DT, Key N, Choi J, Mahale A, Alkatan H, Edward DP, Elkhamary SM, Al-Mesfer S, Maktabi A, Hurtado CG, Lee GY, Carcaboso AM, Mumm JS, Safieh LA, ... Eberhart CG, et al. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. PMID 30401983 DOI: 10.1038/S41388-018-0543-2  0.456
2018 Hodgson NM, Campbell AA, Chang JR, Vizcaino A, Eberhart C, Pearl MS, McCulley TJ. Pituitary Adenoma Apoplexy of the Orbit, Diagnosis, and Management With Presurgical Embolization. Ophthalmic Plastic and Reconstructive Surgery. PMID 30320714 DOI: 10.1097/Iop.0000000000001241  0.35
2018 Tantravedi S, Vesuna F, Winnard PT, Martin A, Lim M, Eberhart CG, Berlinicke C, Raabe E, van Diest PJ, Raman V. Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33. Translational Oncology. 12: 96-105. PMID 30292066 DOI: 10.1016/J.Tranon.2018.09.002  0.435
2018 Poore B, Yuan M, Arnold A, Price A, Alt J, Rubens JA, Slusher BS, Eberhart CG, Raabe EH. mTORC1 inhibition in pediatric low-grade glioma depletes glutathione and therapeutically synergizes with carboplatin. Neuro-Oncology. PMID 30239952 DOI: 10.1093/Neuonc/Noy150  0.385
2018 Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. Plos One. 13: e0204159. PMID 30226859 DOI: 10.1371/Journal.Pone.0204159  0.36
2018 Yuan M, Da Silva ACAL, Arnold A, Okeke L, Ames H, Correa-Cerro LS, Vizcaino MA, Ho CY, Eberhart CG, Rodriguez FJ. MicroRNA (miR) 125b regulates cell growth and invasion in pediatric low grade glioma. Scientific Reports. 8: 12506. PMID 30131528 DOI: 10.1038/S41598-018-30942-4  0.322
2018 Snuderl M, Kannan K, Pfaff E, Wang S, Stafford JM, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton SL, Zagzag D, Chiriboga L, Gardner SL, ... ... Eberhart CG, et al. Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nature Communications. 9: 2868. PMID 30030436 DOI: 10.1038/S41467-018-05029-3  0.36
2018 Cavalli FMG, Hübner JM, Sharma T, Luu B, Sill M, Zapotocky M, Mack SC, Witt H, Lin T, Shih DJH, Ho B, Santi M, Emery L, Hukin J, Dunham C, ... ... Eberhart CG, et al. Heterogeneity within the PF-EPN-B ependymoma subgroup. Acta Neuropathologica. PMID 30019219 DOI: 10.1007/S00401-018-1888-X  0.363
2018 Lopez-Bertoni H, Kozielski K, Rui Y, Lal B, Vaughan H, Wilson D, Mihelson N, Eberhart C, Laterra J, Green JJ. Bioreducible polymeric nanoparticles containing multiplexed cancer stem cell-regulating miRNAs inhibit glioblastoma growth and prolong survival. Nano Letters. PMID 29927251 DOI: 10.1021/Acs.Nanolett.8B00390  0.339
2018 Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM. A UNIQUE TELOMERE DNA EXPANSION PHENOTYPE IN HUMAN RETINAL ROD PHOTORECEPTORS ASSOCIATED WITH AGING AND DISEASE. Brain Pathology (Zurich, Switzerland). PMID 29668072 DOI: 10.1111/Bpa.12618  0.318
2018 Schreck KC, Guajardo A, Lin DDM, Eberhart CG, Grossman SA. Concurrent BRAF/MEK Inhibitors in V600-Mutant High-Grade Primary Brain Tumors. Journal of the National Comprehensive Cancer Network : Jnccn. 16: 343-347. PMID 29632053 DOI: 10.6004/Jnccn.2017.7052  0.404
2018 Ames HM, Rooper LM, Laterra JJ, Eberhart CG, Rodriguez FJ. INSM1 Expression Is Frequent in Primary Central Nervous System Neoplasms but Not in the Adult Brain Parenchyma. Journal of Neuropathology and Experimental Neurology. PMID 29490065 DOI: 10.1093/Jnen/Nly014  0.386
2018 Casaos J, Huq S, Lott T, Felder R, Choi J, Gorelick N, Peters M, Xia Y, Maxwell R, Zhao T, Ji C, Simon T, Sesen J, Scotland SJ, Kast RE, ... ... Eberhart CG, et al. Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. Oncotarget. 9: 8054-8067. PMID 29487714 DOI: 10.18632/Oncotarget.23883  0.467
2018 Brosnan-Cashman JA, Graham MK, Rizzo AJ, Myers K, Zhang R, Göger E, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract B14: Establishment and characterization of in vitro models of alternative lengthening of telomeres (ALT) in pediatric high-grade glioma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B14  0.372
2018 Guo H, Kaur H, Akhtarkhavari S, Eberhart CG, Raabe EH. Abstract 4850: The minor groove binding agent quinacrine inhibits growth and increases apoptotic death in diffuse intrinsic pontine glioma tumor cells Cancer Research. 78: 4850-4850. DOI: 10.1158/1538-7445.Am2018-4850  0.448
2018 Arnold A, Yuan M, Rodriguez FJ, Eberhart CG, Raabe EH. Abstract 4629: Synergistic growth inhibitor effect on a patient derived NF1 pilocytic astrocytoma cell line with the dual mTORC1/2 inhibitor TAK228 and MEK inhibitor trametinib Cancer Research. 78: 4629-4629. DOI: 10.1158/1538-7445.Am2018-4629  0.444
2018 Maxwell MJ, Poore B, Hanaford A, Alt J, Rais R, Slusher BS, Eberhart CG, Raabe EH. Abstract 3521: Glutamine metabolic inhibition synergizes with L-asparaginase in MYCN-amplified neuroblastoma Cancer Research. 78: 3521-3521. DOI: 10.1158/1538-7445.Am2018-3521  0.414
2018 Wang SZ, Poore B, Alt J, Rais R, Allen S, Orr B, Slusher B, Eberhart C, Raabe E, Rubens J. Abstract 3519: Disrupting glutamine metabolism depletes glutathione and sensitizes atypical teratoid/rhabdoid tumor to carboplatin Cancer Research. 78: 3519-3519. DOI: 10.1158/1538-7445.Am2018-3519  0.454
2018 Park Y, An P, Ding D, Eberhart CG, Raabe EH. Abstract 3182: A human neural stem cell glial brain tumor model identifies the relative contribution of different oncogenic elements to malignant transformation Cancer Research. 78: 3182-3182. DOI: 10.1158/1538-7445.Am2018-3182  0.45
2018 Arnold A, Yuan M, Rodriguez F, Eberhart C, Raabe E. PDCT-02. COMBINED INHIBITION OF MTORC1/C2 AND MEK PATHWAY IS SYNERGISTIC IN PRECLINICAL TESTING OF PEDIATRIC LOW-GRADE GLIOMA INCLUDING A NOVEL PATIENT-DERIVED NF1 PILOCYTIC ASTROCYTOMA CELL LINE Neuro-Oncology. 20: vi200-vi201. DOI: 10.1093/Neuonc/Noy148.832  0.363
2018 Maynard R, Hanaford A, Poore B, Rubens J, Archer T, Tamayo P, Pomeroy S, Eberhart C, Raabe E. MBRS-30. TORC1/2 INHIBITION SENSITIZES MYC-DRIVEN MEDULLOBLASTOMA CELLS TO CARBOPLATIN CHEMOTHERAPY Neuro-Oncology. 20: i134-i135. DOI: 10.1093/Neuonc/Noy059.475  0.335
2018 Arnold A, Yuan M, Rodriguez F, Eberhart C, Raabe E. LGG-52. DUAL INHIBITION OF mTORC1/C2 AND MEK PATHWAY IS SYNERGISTIC IN MULTIPLE HUMAN MODELS OF PEDIATRIC LOW-GRADE GLIOMA INCLUDING A NOVEL PATIENT-DERIVED NF1 PILOCYTIC ASTROCYTOMA CELL LINE Neuro-Oncology. 20: i115-i116. DOI: 10.1093/Neuonc/Noy059.393  0.373
2018 Poore B, Yuan M, Arnold A, Price A, Alt J, Rubens J, Slusher B, Eberhart C, Raabe E. Lgg-51. Metabolic Profiling In Pediatric Low Grade Glioma Identifies Glutathione Depletion After Mtorc1 Inhibition And Validates Everolimus And Carboplatin As A Potential Combination Therapy Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.392  0.3
2018 Pietsch T, Figarella-Branger D, Giangaspero F, Gessi M, Hawkins C, Jacques T, Korshunov A, Eberhart C, Burger P, Hoff Kv, Kool M, Haberler C. Embr-12. Improved Diagnostic Algorithm For Differential Diagnostics Of Cns Embryonal Tumors (Former Cns-Pnet) By Neuropathological Re-Evaluation Of 256 Cases And Crossvalidation By Methylation Classification Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.196  0.324
2018 Shah S, Rubens J, Eberhart C, Raabe E. DIPG-62. CARBOPLATIN SYNERGIZES WITH BCL-2 INHIBITOR TO POTENTIATE KILLING OF DIPG CELLS Neuro-Oncology. 20: i61-i61. DOI: 10.1093/Neuonc/Noy059.155  0.321
2018 Park Y, An P, Ding D, Eberhart CG, Raabe EH. DIPG-34. A HUMAN NEURAL STEM CELL DIPG MODEL IDENTIFIES THE RELATIVE CONTRIBUTION OF DIFFERENT ONCOGENIC ELEMENTS TO INVASIVE MALIGNANT TRANSFORMATION Neuro-Oncology. 20: i55-i56. DOI: 10.1093/Neuonc/Noy059.127  0.34
2018 Shahab S, Rubens J, Eberhart C, Raabe E. ATRT-37. TARGETING ATYPICAL TERATOID/RHABDOID TUMOR USING MATURE LET-7 LEADS TO INCREASED APOPTOSIS Neuro-Oncology. 20: i35-i36. DOI: 10.1093/Neuonc/Noy059.034  0.379
2018 Kaur H, Guo H, Shah S, Akhtarkhavari S, Eberhart C, Raabe E. ATRT-33. TARGETING THE LETHAL PEDIATRIC TUMORS ATRT AND DIPG WITH THE DNA MINOR-GROOVE BINDING AGENT QUINACRINE Neuro-Oncology. 20: i34-i35. DOI: 10.1093/Neuonc/Noy059.030  0.32
2018 Sajesh B, Ngoc O, Omar R, Fediuk H, Li L, Alrushaid S, Wang W, Pu J, Sun H, Siahaan T, Werbowetski-Ogilvie T, Wölfl M, Remke M, Ramaswamy V, Taylor M, ... Eberhart C, et al. 18 Peroxiredoxin1 is a therapeutic target in group-3 medulloblastoma Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S16-S16. DOI: 10.1017/cjn.2018.304  0.308
2017 Wu CC, Hou S, Orr BA, Kuo BR, Youn YH, Ong T, Roth F, Eberhart CG, Robinson GW, Solecki DJ, Taketo MM, Gilbertson RJ, Roussel MF, Han YG. mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma. Developmental Cell. PMID 29103956 DOI: 10.1016/J.Devcel.2017.10.011  0.317
2017 Mangraviti A, Raghavan T, Volpin F, Skuli N, Gullotti D, Zhou J, Asnaghi L, Sankey E, Liu A, Wang Y, Lee DH, Gorelick N, Serra R, Peters M, Schriefer D, ... ... Eberhart CG, et al. HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy. Scientific Reports. 7: 14978. PMID 29097800 DOI: 10.1038/S41598-017-14990-W  0.397
2017 Semenkow S, Li S, Kahlert UD, Raabe EH, Xu J, Arnold A, Janowski M, Oh BC, Brandacher G, Bulte JWM, Eberhart CG, Walczak P. An immunocompetent mouse model of human glioblastoma. Oncotarget. 8: 61072-61082. PMID 28977847 DOI: 10.18632/Oncotarget.17851  0.392
2017 Yang Q, Tripathy A, Yu W, Eberhart CG, Asnaghi L. Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells. Experimental Eye Research. PMID 28689747 DOI: 10.1016/J.Exer.2017.07.001  0.409
2017 Rubens JA, Wang SZ, Price A, Weingart MF, Allen SJ, Orr BA, Eberhart CG, Raabe EH. The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity. Neuro-Oncology. PMID 28582547 DOI: 10.1093/Neuonc/Nox067  0.432
2017 Miyahara H, Yadavilli S, Natsumeda M, Rubens J, Rodgers L, Kambhampati M, Taylor I, Kaur H, Asnaghi L, Eberhart CG, Warren KE, Nazarian J, Raabe EH. The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma. Cancer Letters. PMID 28450157 DOI: 10.1016/J.Canlet.2017.04.019  0.433
2017 Zhang C, Nance EA, Mastorakos P, Chisholm J, Berry S, Eberhart C, Tyler B, Brem H, Suk JS, Hanes J. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28279797 DOI: 10.1016/J.Jconrel.2017.03.007  0.333
2017 Qin H, Janowski M, Pearl MS, Malysz-Cymborska I, Li S, Eberhart CG, Walczak P. Rabbit Model of Human Gliomas: Implications for Intra-Arterial Drug Delivery. Plos One. 12: e0169656. PMID 28103265 DOI: 10.1371/Journal.Pone.0169656  0.378
2017 Arnold A, Rodriguez F, Eberhart CG, Raabe EH. Abstract 703: Combinatory treatment for pediatric low grade glioma with the dual mTORC1/2 inhibitor TAK228 and MEK inhibitor Trametinib Cancer Research. 77: 703-703. DOI: 10.1158/1538-7445.Am2017-703  0.441
2017 Wang S, Rubens J, Allen S, Orr B, Eberhart C, Raabe E. Abstract 5182: Targeting abnormal metabolism downstream of MYC in atypical teratoid/rhabdoid tumors Cancer Research. 77: 5182-5182. DOI: 10.1158/1538-7445.Am2017-5182  0.44
2017 Guo H, Akhtarkhavari S, Eberhart CG, Kaur H, Raabe EH. Abstract 3868: The stem cell factor LIN28B regulates proliferation and apoptosis in diffuse intrinsic pontine glioma Cancer Research. 77: 3868-3868. DOI: 10.1158/1538-7445.Am2017-3868  0.466
2017 Kaur H, Ali SZ, Guo H, Akhtarkhavari S, Rodriguez F, Eberhart CG, Raabe EH. Abstract 3865: Targeting the epigenetic modifier HMGA2 in lethal adult and pediatric gliomas inhibits invasion, growth and tumorigenicity Cancer Research. 77: 3865-3865. DOI: 10.1158/1538-7445.Am2017-3865  0.475
2017 Hanaford AR, Poore B, Eberhart CG, Raabe EH. Abstract 3560: 6-diazo-5-oxo-norleucine resistant MYC-driven medulloblastoma tumors are sensitive to inhibition of glutaminase suggesting a possible glutaminase-independent mechanism of resistance Cancer Research. 77: 3560-3560. DOI: 10.1158/1538-7445.Am2017-3560  0.314
2017 Poore BA, Taylor I, Rubens J, Hanaford A, Maxwell M, Eberhart C, Raabe E. Abstract 3549: C-MYC sensitizes GBM with primitive features to glutamine metabolism disruption Cancer Research. 77: 3549-3549. DOI: 10.1158/1538-7445.Am2017-3549  0.424
2017 Brosnan-Cashman JA, Rizzo AJ, Goger E, Myers KM, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3466: ALT-positive pediatric high grade glioma cells display chemosensitivity to ATR pathway inhibition Cancer Research. 77: 3466-3466. DOI: 10.1158/1538-7445.Am2017-3466  0.392
2017 Brosnan-Cashman JA, Yuan M, Rizzo AJ, Myers KM, Barry WT, Davis C, Esopi DM, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3465: Context-dependent effects of ATRX loss on telomere biology in glioma cells Cancer Research. 77: 3465-3465. DOI: 10.1158/1538-7445.Am2017-3465  0.39
2017 Xu Q, Wang K, Ahsan S, Rodriguez F, Eberhart C, Jiang Y, Laterra J, Li Y. Abstract 1471: miR-148a-3p regulation of OTX2 and PRC2 in group 3 and 4 medulloblastoma Cancer Research. 77: 1471-1471. DOI: 10.1158/1538-7445.Am2017-1471  0.301
2017 Arnold A, Rodriguez F, Eberhart C, Raabe E. LGG-13. SYNERGISTIC TREATMENT FOR PEDIATRIC LOW GRADE GLIOMA WITH THE DUAL MTORC1/2 INHIBITOR TAK-228 AND MEK INHIBITOR TRAMETINIB Neuro-Oncology. 19: iv35-iv36. DOI: 10.1093/Neuonc/Nox083.146  0.434
2017 Rubens J, Wang S, Price A, Allen S, Orr B, Eberhart C, Raabe E. ATRT-08. TARGETING GLUTAMINE METABOLISM IN MYC DRIVEN ATYPICAL TERATOID RHABDOID TUMORS Neuro-Oncology. 19: iv2-iv3. DOI: 10.1093/Neuonc/Nox083.007  0.36
2016 Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, Eberhart CG. Targeting Notch signaling as a novel therapy for retinoblastoma. Oncotarget. PMID 27661116 DOI: 10.18632/Oncotarget.12142  0.388
2016 Kaur H, Ali SZ, Huey L, Hütt-Cabezas M, Taylor I, Mao XG, Weingart M, Chu Q, Rodriguez FJ, Eberhart CG, Raabe EH. The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma. Cancer Letters. PMID 27102002 DOI: 10.1016/J.Canlet.2016.04.020  0.448
2016 Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL. Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. Plos One. 11: e0150271. PMID 27028405 DOI: 10.1371/Journal.Pone.0150271  0.41
2016 Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dančík V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees M, Shamji AF, ... ... Eberhart CG, et al. DiSCoVERing innovative therapies for rare tumors: combining genetically accurate disease models with in silico analysis to identify novel therapeutic targets. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27012813 DOI: 10.1158/1078-0432.Ccr-15-3011  0.349
2016 Mahale A, Alkatan H, Alwadani S, Othman M, Suarez MJ, Price A, Al-Hussain H, Jastaneiah S, Yu W, Maktabi A, Deepak EP, Eberhart CG, Asnaghi L. Altered gene expression in conjunctival squamous cell carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26916071 DOI: 10.1038/Modpathol.2016.41  0.334
2016 Sahm F, Jakobiec FA, Meyer J, Schrimpf D, Eberhart CG, Hovestadt V, Capper D, Lambo S, Ryzhova M, Schüller U, Zheludkova O, Kumirova E, Lichter P, von Deimling A, Jones DT, et al. Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas. Genes, Chromosomes & Cancer. PMID 26841698 DOI: 10.1002/Gcc.22344  0.362
2016 Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, ... ... Eberhart C, et al. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics. PMID 26829751 DOI: 10.1038/Ng.3500  0.41
2016 Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma. Oncotarget. PMID 26761211 DOI: 10.18632/Oncotarget.6868  0.309
2016 Ahsan S, Haffner M, Eberhart C, Raabe E. Abstract 4440: Diffuse intrinsic pontine glioma epigenetic marks change depending on cell culture conditions: Implications for investigating epigenetically directed therapy Cancer Research. 76: 4440-4440. DOI: 10.1158/1538-7445.Am2016-4440  0.446
2016 Hanaford AR, Archer TC, Price A, Kahlert U, Maciaczyk J, Guido N, Kim W, Ehrenberger T, Clemons P, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart M, Rees M, Shamji A, ... ... Eberhart CG, et al. Abstract 2476: DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets Cancer Research. 76: 2476-2476. DOI: 10.1158/1538-7445.Am2016-2476  0.343
2016 Kaur H, Hütt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart CG, Raabe EH. Abstract 2464: Disrupting the epigenetic modifier HMGA2 in DIPG and GBM inhibits tumor invasion, growth and tumorigenicity Cancer Research. 76: 2464-2464. DOI: 10.1158/1538-7445.Am2016-2464  0.395
2016 Rubens J, Price A, Orr B, Eberhart C, Raabe E. Abstract 2102: Targeting mTOR downstream of LIN28 in atypical teratoid rhabdoid tumors promotes apoptosis and suppresses tumorigenicity Cancer Research. 76: 2102-2102. DOI: 10.1158/1538-7445.Am2016-2102  0.416
2016 Kaur H, Hütt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart C, Raabe E. PDTB-11. DISRUPTING THE EPIGENETIC MODIFIER HMGA2 IN LETHAL PEDIATRIC AND ADULT GLIOMAS INHIBITS INVASION, GROWTH AND TUMORIGENICITY Neuro-Oncology. 18: vi152-vi152. DOI: 10.1093/Neuonc/Now212.631  0.31
2016 Rubens J, Price A, Eberhart C, Raabe E. AT-14mTOR INHIBITION BLOCKS A KEY LIN28 DOWNSTREAM TARGET AND ENHANCES CISPLATIN MEDIATED CYTOTOXICITY LEADING TO EXTENDED SURVIVAL IN ATYPICAL TERATOID RHABDOID TUMORS Neuro-Oncology. 18: iii4.2-iii4. DOI: 10.1093/Neuonc/Now065.13  0.4
2015 Natsumeda M, Maitani K, Liu Y, Miyahara H, Kaur H, Chu Q, Zhang H, Kahlert U, Eberhart CG. Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres. Brain Pathology (Zurich, Switzerland). PMID 26613556 DOI: 10.1111/Bpa.12343  0.412
2015 Jenkins NC, Rao G, Eberhart CG, Pedone CA, Dubuc AM, Fults DW. Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice. Journal of Neuro-Oncology. PMID 26518543 DOI: 10.1007/S11060-015-1985-9  0.46
2015 Dietrich U, Koch K, Suwala AK, Hartmann R, Cheng M, Maciaczyk D, Willbold D, Eberhart CG, Glunde K, Maciaczyk J. The effect of neurosphere culture conditions on the cellular metabolism of glioma cells. Folia Neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences. 53: 219-25. PMID 26443312 DOI: 10.5114/Fn.2015.54422  0.359
2015 Kahlert UD, Cheng M, Koch K, Marchionni L, Fan X, Raabe EH, Maciaczyk J, Glunde K, Eberhart CG. Alterations in Cellular Metabolome after Pharmacological Inhibition of Notch in Glioblastoma Cells. International Journal of Cancer. Journal International Du Cancer. PMID 26422827 DOI: 10.1002/Ijc.29873  0.424
2015 Kahlert UD, Suwala AK, Koch K, Natsumeda M, Orr BA, Hayashi M, Maciaczyk J, Eberhart CG. Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells. Journal of Neuropathology and Experimental Neurology. 74: 889-900. PMID 26222502 DOI: 10.1097/Nen.0000000000000227  0.46
2015 Vizcaíno MA, Shah S, Eberhart CG, Rodriguez FJ. Clinicopathologic implications of NF1 gene alterations in diffuse gliomas. Human Pathology. PMID 26190195 DOI: 10.1016/J.Humpath.2015.05.014  0.322
2015 Korshunov A, Jakobiec FA, Eberhart CG, Hovestadt V, Capper D, Jones DT, Sturm D, Stagner AM, Edward DP, Eagle RC, Proia AD, Koch A, Ryzhova M, Ektova A, Schüller U, et al. Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 26183384 DOI: 10.1111/Neup.12227  0.384
2015 Taylor IC, Hütt-Cabezas M, Brandt WD, Kambhampati M, Nazarian J, Chang HT, Warren KE, Eberhart CG, Raabe EH. Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition. Journal of Neuropathology and Experimental Neurology. PMID 26115193 DOI: 10.1097/Nen.0000000000000216  0.431
2015 Wang X, Dubuc AM, Ramaswamy V, Mack S, Gendoo DM, Remke M, Wu X, Garzia L, Luu B, Cavalli F, Peacock J, López B, Skowron P, Zagzag D, Lyden D, ... ... Eberhart C, et al. Medulloblastoma subgroups remain stable across primary and metastatic compartments. Acta Neuropathologica. 129: 449-57. PMID 25689980 DOI: 10.1007/S00401-015-1389-0  0.385
2015 Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, ... ... Eberhart CG, et al. Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target. Oncotarget. 6: 3165-77. PMID 25638158 DOI: 10.18632/Oncotarget.3078  0.492
2015 Kaur H, Hütt-Cabezas M, Weingart MF, Xu J, Kuwahara Y, Erdreich-Epstein A, Weissman BE, Eberhart CG, Raabe EH. The chromatin-modifying protein HMGA2 promotes atypical teratoid/rhabdoid cell tumorigenicity. Journal of Neuropathology and Experimental Neurology. 74: 177-85. PMID 25575139 DOI: 10.1097/Nen.0000000000000161  0.472
2015 Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Notch signaling activation in pediatric low-grade astrocytoma. Journal of Neuropathology and Experimental Neurology. 74: 121-31. PMID 25575134 DOI: 10.1097/Nen.0000000000000155  0.76
2015 Lim KJ, Brandt WD, Heth JA, Muraszko KM, Fan X, Bar EE, Eberhart CG. Lateral inhibition of Notch signaling in neoplastic cells. Oncotarget. 6: 1666-77. PMID 25557173 DOI: 10.18632/Oncotarget.2762  0.755
2015 Borodovsky A, Meeker AK, Kirkness EF, Zhao Q, Eberhart CG, Gallia GL, Riggins GJ. A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres. Journal of Neuro-Oncology. 121: 479-87. PMID 25471051 DOI: 10.1007/S11060-014-1672-2  0.319
2015 Orr BA, Eberhart CG. Molecular pathways: not a simple tube--the many functions of blood vessels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 18-23. PMID 25074609 DOI: 10.1158/1078-0432.Ccr-13-1641  0.422
2015 Ho CY, Mosier S, Safneck J, Salomao DR, Miller NR, Eberhart CG, Gocke CD, Batista DA, Rodriguez FJ. Genetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningioma. Brain Pathology (Zurich, Switzerland). 25: 193-201. PMID 24773246 DOI: 10.1111/Bpa.12150  0.341
2015 Snuderl M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner SL, Allen JC, Wisoff JH, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister SM, et al. Abstract LB-172: Novel candidate oncogenic drivers in pineoblastoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-172  0.394
2015 Hanaford A, Guerra C, Eberhart C, Raabe E, Price A. Abstract 504: Glutamine metabolic inhibitors suppress growth and tumorigenicity in MYC and MYCN-driven pediatric malignancies Cancer Research. 75: 504-504. DOI: 10.1158/1538-7445.Am2015-504  0.348
2015 Taylor I, Ahsan S, Price A, Eberhart C, Raabe EH. Abstract 494: MYC, dominant negative p53 and AKT transform human neural stem cells into primitive neuro-ectodermal tumors sensitive to glutaminase inhibitors Cancer Research. 75: 494-494. DOI: 10.1158/1538-7445.Am2015-494  0.459
2015 Kaur H, Hütt-Cabezas M, Taylor I, Asnaghi L, Rodriguez F, Orr BA, Eberhart CG, Raabe EH. Abstract 4222: Targeting HMGA2 suppresses GBM stemness, invasion and tumorigenicity Cancer Research. 75: 4222-4222. DOI: 10.1158/1538-7445.Am2015-4222  0.48
2015 Rubens J, Weingart M, Price A, Hutt-Cabezas M, Taylor I, Allen S, Orr B, Eberhart C, Raabe E. Abstract 3272: Targeting LIN28 and the RAS/MAP kinase pathway in atypical teratoid rhabdoid tumors Cancer Research. 75: 3272-3272. DOI: 10.1158/1538-7445.Am2015-3272  0.467
2015 Sagal J, Eberhart CG, Ying M. Abstract 2892: A MYC-driven medulloblastoma model derived from human induced pluripotent stem cells Cancer Research. 75: 2892-2892. DOI: 10.1158/1538-7445.Am2015-2892  0.465
2015 Natsumeda M, Miyahara H, Kaur H, Eberhart C. MTR-10PHARMACOLOGICAL NOTCH BLOCKADE IN GLIOMAS INDUCES AUTOPHAGY AND COMBINATION TREATMENT WITH AN AUTOPHAGY INHIBITOR INCREASES TUMOR CELL DEATH Neuro-Oncology. 17: v126.2-v126. DOI: 10.1093/Neuonc/Nov219.10  0.396
2015 Yuan M, An P, Lim KS, Taylor I, Rodriguez F, Raabe E, Eberhart C. MTR-03ATRX REDUCTION PROMOTES ALKYLATING AGENT RESISTANCE AND XENOGRAFT GROWTH IN A SUBSET OF GLIOMAS Neuro-Oncology. 17: v124.3-v124. DOI: 10.1093/Neuonc/Nov219.03  0.409
2015 Karajannis M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner S, Allen J, Wisoff J, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister S, et al. GENO-20NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA Neuro-Oncology. 17: v95.4-v96. DOI: 10.1093/Neuonc/Nov215.20  0.393
2015 Mangraviti A, Raghavan T, Volpin F, Skuli N, Zhou J, Eberhart C, Rodriguez F, Sankey E, Gullotti D, Liu A, Wang Y, Schriefer D, Brem H, Olivi A, Tyler B. ATPS-89LOCAL DELIVERY OF A SMALL-MOLECULE INHIBITOR OF HYPOXIA INDUCIBLE FACTOR-1: A NEW CANDIDATE DRUG FOR BRAIN TUMOR THERAPY Neuro-Oncology. 17: v38.1-v38. DOI: 10.1093/Neuonc/Nov204.89  0.428
2015 Snuderl M, Kannan K, Aminova O, Dolgalev I, Heguy A, Faustin A, Zagzag D, Gardner S, Allen J, Wisoff J, Capper D, Hovestadt V, Ahsan S, Eberhart C, Pfister S, et al. MB-17 * NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA Neuro-Oncology. 17: iii23-iii23. DOI: 10.1093/Neuonc/Nov061.93  0.387
2015 Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Lg-04Notch Signaling Activation In Pediatric Low-Grade Astrocytoma. Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.73  0.428
2015 Rubens J, Price A, Eberhart C, Raabe E. AT-05 * TARGETING mTOR DOWNSTREAM OF LIN28 IN ATYPICAL TERATOID RHABDOID TUMORS PROMOTES APOPTOSIS AND SUPPRESSES TUMORIGENICITY Neuro-Oncology. 17: iii2-iii2. DOI: 10.1093/Neuonc/Nov061.5  0.418
2015 Taylor I, Ahsan S, Weingart M, Eberhart C, Raabe E. HG-12 * LIN28 AND MYC EXPRESSING PEDIATRIC GLIOBLASTOMAS ARE SENSITIVE TO INHIBITORS OF GLUTAMINE METABOLISM Neuro-Oncology. 17: iii13-iii13. DOI: 10.1093/Neuonc/Nov061.49  0.416
2015 Kaur H, Hutt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart C, Raabe E. HG-08 * DISRUPTING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND GBM INHIBITS TUMOR INVASION, GROWTH AND TUMORIGENICITY Neuro-Oncology. 17: iii12-iii12. DOI: 10.1093/Neuonc/Nov061.45  0.491
2015 Hanaford A, Archer T, Tamayo P, Pomeroy S, Eberhart C, Raabe E. MB-27 * PATHWAY ANALYSIS OF A HUMAN NEURAL STEM CELL MODEL OF AGGRESSIVE MEDULLOBLASTOMA REVEALS CKD INBHIBITION AS A POTENTIAL THERAPEUTIC MODALITY Neuro-Oncology. 17: iii25-iii26. DOI: 10.1093/Neuonc/Nov061.103  0.478
2014 Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, ... ... Eberhart CG, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathologica Communications. 2: 174. PMID 25539912 DOI: 10.1186/S40478-014-0174-Y  0.361
2014 Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart CG. ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain Pathology (Zurich, Switzerland). PMID 25521330 DOI: 10.1111/Bpa.12240  0.776
2014 Asnaghi L, Alkatan H, Mahale A, Othman M, Alwadani S, Al-Hussain H, Jastaneiah S, Yu W, Maktabi A, Edward DP, Eberhart CG. Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma. Investigative Ophthalmology & Visual Science. 55: 8604-13. PMID 25491297 DOI: 10.1167/Iovs.14-14920  0.331
2014 Lopez-Bertoni H, Lal B, Li A, Caplan M, Guerrero-Cázares H, Eberhart CG, Quiñones-Hinojosa A, Glas M, Scheffler B, Laterra J, Li Y. DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2. Oncogene. PMID 25328136 DOI: 10.1038/Onc.2014.334  0.444
2014 Matthaei M, Zhu AY, Kallay L, Eberhart CG, Cursiefen C, Jun AS. Transcript profile of cellular senescence-related genes in Fuchs endothelial corneal dystrophy. Experimental Eye Research. 129: 13-7. PMID 25311168 DOI: 10.1016/J.Exer.2014.10.011  0.321
2014 Martin AM, Raabe E, Eberhart C, Cohen KJ. Management of pediatric and adult patients with medulloblastoma. Current Treatment Options in Oncology. 15: 581-94. PMID 25194927 DOI: 10.1007/S11864-014-0306-4  0.357
2014 Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG. Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation. Plos One. 9: e105372. PMID 25166211 DOI: 10.1371/Journal.Pone.0105372  0.736
2014 Rajaii F, Asnaghi L, Enke R, Merbs SL, Handa JT, Eberhart CG. The demethylating agent 5-Aza reduces the growth, invasiveness, and clonogenicity of uveal and cutaneous melanoma. Investigative Ophthalmology & Visual Science. 55: 6178-86. PMID 25146981 DOI: 10.1167/Iovs.14-13933  0.356
2014 Ahsan S, Raabe EH, Haffner MC, Vaghasia A, Warren KE, Quezado M, Ballester LY, Nazarian J, Eberhart CG, Rodriguez FJ. Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma. Acta Neuropathologica Communications. 2: 59. PMID 24894482 DOI: 10.1186/2051-5960-2-59  0.357
2014 Spence T, Sin-Chan P, Picard D, Barszczyk M, Hoss K, Lu M, Kim SK, Ra YS, Nakamura H, Fangusaro J, Hwang E, Kiehna E, Toledano H, Wang Y, Shi Q, ... ... Eberhart CG, et al. CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity. Acta Neuropathologica. 128: 291-303. PMID 24839957 DOI: 10.1007/S00401-014-1291-1  0.415
2014 AlWadani S, Robinson S, Myers R, Akpek EK, Eberhart CG. No increase in IgG4-positive plasma cells in limbal Rosai-Dorfman disease. Cornea. 33: 844-7. PMID 24831194 DOI: 10.1097/Ico.0000000000000141  0.346
2014 Yuan M, Eberhart CG, Kai M. RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation. Oncotarget. 5: 2820-6. PMID 24811242 DOI: 10.18632/Oncotarget.1924  0.431
2014 Karajannis MA, Legault G, Fisher MJ, Milla SS, Cohen KJ, Wisoff JH, Harter DH, Goldberg JD, Hochman T, Merkelson A, Bloom MC, Sievert AJ, Resnick AC, Dhall G, Jones DT, ... ... Eberhart CG, et al. Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas. Neuro-Oncology. 16: 1408-16. PMID 24803676 DOI: 10.1093/Neuonc/Nou059  0.305
2014 Carvalho FL, Simons BW, Eberhart CG, Berman DM. Notch signaling in prostate cancer: a moving target. The Prostate. 74: 933-45. PMID 24737393 DOI: 10.1002/Pros.22811  0.347
2014 Tilghman J, Wu H, Sang Y, Shi X, Guerrero-Cazares H, Quinones-Hinojosa A, Eberhart CG, Laterra J, Ying M. HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells. Cancer Research. 74: 3168-79. PMID 24710409 DOI: 10.1158/0008-5472.Can-13-2103  0.46
2014 Ding D, Lim KS, Eberhart CG. Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres. Acta Neuropathologica Communications. 2: 31. PMID 24685274 DOI: 10.1186/2051-5960-2-31  0.45
2014 Rodić N, Sharma R, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA, Maitra A, Torbenson MS, Goggins M, Shih IeM, Duffield AS, Montgomery EA, Gabrielson E, ... ... Eberhart CG, et al. Long interspersed element-1 protein expression is a hallmark of many human cancers. The American Journal of Pathology. 184: 1280-6. PMID 24607009 DOI: 10.1016/J.Ajpath.2014.01.007  0.346
2014 Lim KS, Lim KJ, Price AC, Orr BA, Eberhart CG, Bar EE. Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner. Oncogene. 33: 4433-41. PMID 24077291 DOI: 10.1038/Onc.2013.390  0.771
2014 Ahsan S, Raabe E, Haffner MC, Nazarian J, Warren K, Ballester L, Quezado M, Eberhart C, Rodriguez FJ. Abstract 384: Epigenetic derangements in histone and cytosine methylation are unique to diffuse intrinsic pontine glioma (DIPG) Cancer Research. 74: 384-384. DOI: 10.1158/1538-7445.Am2014-384  0.36
2014 Taylor IC, Hutt-Cabezas M, Weingart M, Warren K, Chang H, Nazarian J, Eberhart CG, Raabe EH. Abstract 3099: Dual targeting of mTOR and Notch disrupts growth and promotes apoptosis in diffuse intrinsic pontine glioma Cancer Research. 74: 3099-3099. DOI: 10.1158/1538-7445.Am2014-3099  0.44
2014 Hanaford AR, Eberhart CG, Raabe EH. Abstract 3090: Targeting glutamine metabolism as a therapeutic strategy in MYC-driven medulloblastoma Cancer Research. 74: 3090-3090. DOI: 10.1158/1538-7445.Am2014-3090  0.388
2014 Kaur H, Hütt M, Mao X, Orr BA, Eberhart CG, Raabe EH. Abstract 3031: HMGA2 promotes invasion and stemness in glioblastoma Cancer Research. 74: 3031-3031. DOI: 10.1158/1538-7445.Am2014-3031  0.463
2014 Kahlert UD, Raabe EE, Siebzehnrubl FA, Bar EE, Maciaczyk J, Eberhart CG. Abstract 1038: ZEB1 plays a pivotal role in hypoxia-mediated increase ofin vitroinvasion of glioblastoma-derived cell cultures and represents a novel neural stem cell marker in early development Cancer Research. 74: 1038-1038. DOI: 10.1158/1538-7445.Am2014-1038  0.465
2014 Wang J, Eberhart C, Ellison D, Vandenberg S, Wechsler-Reya R. PM-22 * GENETICALLY ENGINEERED MOUSE MODELS OF CHOROID PLEXUS TUMORS Neuro-Oncology. 16: v173-v173. DOI: 10.1093/Neuonc/Nou268.22  0.473
2014 Natsumeda M, Zhang H, Kaur H, Asnaghi L, Eberhart CG. DS-02 * INDUCTION OF AUTOPHAGY MARKERS IN GLIOMAS FOLLOWING PHARMACOLOGICAL NOTCH BLOCKADE Neuro-Oncology. 16: v65-v65. DOI: 10.1093/Neuonc/Nou244.2  0.39
2014 Laterra J, Lopez-Bertoni H, Lal B, Li A, Caplan M, Guerrero-Cazares H, Eberhart CG, Quinones-Hinojosa A, Li Y. EPIGENETIC REGULATION OF GBM CELL STEMNESS AND TUMOR PROPAGATING CAPACITY BY OCT4 AND SOX2 Neuro-Oncology. 16: iii15-iii15. DOI: 10.1093/Neuonc/Nou206.54  0.347
2014 Eberhart C, Raabe E, Hanaford A, Pomeroy S. MODELLING HIGH MYC MEDULLOBLASTOMA AND OTHER BRAIN TUMORS USING HUMAN NEURAL STEM CELLS Neuro-Oncology. 16: iii4-iii4. DOI: 10.1093/Neuonc/Nou206.12  0.473
2013 Baia GS, Caballero OL, Ho JS, Zhao Q, Cohen T, Binder ZA, Salmasi V, Gallia GL, Quinones-Hinojosa A, Olivi A, Brem H, Burger P, Strausberg RL, Simpson AJ, Eberhart CG, et al. NY-ESO-1 expression in meningioma suggests a rationale for new immunotherapeutic approaches. Cancer Immunology Research. 1: 296-302. PMID 24777967 DOI: 10.1158/2326-6066.Cir-13-0029  0.377
2013 Hütt-Cabezas M, Karajannis MA, Zagzag D, Shah S, Horkayne-Szakaly I, Rushing EJ, Cameron JD, Jain D, Eberhart CG, Raabe EH, Rodriguez FJ. Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-Oncology. 15: 1604-14. PMID 24203892 DOI: 10.1093/Neuonc/Not132  0.412
2013 Remke M, Ramaswamy V, Peacock J, Shih DJ, Koelsche C, Northcott PA, Hill N, Cavalli FM, Kool M, Wang X, Mack SC, Barszczyk M, Morrissy AS, Wu X, Agnihotri S, ... ... Eberhart CG, et al. TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathologica. 126: 917-29. PMID 24174164 DOI: 10.1007/S00401-013-1198-2  0.319
2013 Binder ZA, Siu IM, Eberhart CG, Ap Rhys C, Bai RY, Staedtke V, Zhang H, Smoll NR, Piantadosi S, Piccirillo SG, Dimeco F, Weingart JD, Vescovi A, Olivi A, Riggins GJ, et al. Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome. Plos One. 8: e75945. PMID 24146797 DOI: 10.1371/Journal.Pone.0075945  0.432
2013 Borodovsky A, Salmasi V, Turcan S, Fabius AW, Baia GS, Eberhart CG, Weingart JD, Gallia GL, Baylin SB, Chan TA, Riggins GJ. 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. Oncotarget. 4: 1737-47. PMID 24077805 DOI: 10.18632/Oncotarget.1408  0.393
2013 Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger PC, Eberhart CG, Rodriguez FJ, Raabe E, Nazarian J, Warren K, Quezado MM. Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas. The American Journal of Surgical Pathology. 37: 1357-64. PMID 24076776 DOI: 10.1097/Pas.0B013E318294E817  0.449
2013 Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathologica. 126: 607-8. PMID 24022427 DOI: 10.1007/S00401-013-1174-X  0.389
2013 Xin X, Rodrigues M, Umapathi M, Kashiwabuchi F, Ma T, Babapoor-Farrokhran S, Wang S, Hu J, Bhutto I, Welsbie DS, Duh EJ, Handa JT, Eberhart CG, Lutty G, Semenza GL, et al. Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4. Proceedings of the National Academy of Sciences of the United States of America. 110: E3425-34. PMID 23959876 DOI: 10.1073/Pnas.1217091110  0.338
2013 Odia Y, Orr BA, Bell WR, Eberhart CG, Rodriguez FJ. cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome. Journal of Neuro-Oncology. 115: 249-59. PMID 23934175 DOI: 10.1007/S11060-013-1221-4  0.379
2013 Rodrigues M, Iliff NT, Eberhart CG, Montaner S, Sodhi A. Scleral penetration of an unusually aggressive case of a retinal hemangioblastoma. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 48: e67-71. PMID 23931485 DOI: 10.1016/J.Jcjo.2013.01.014  0.323
2013 Spina R, Filocamo G, Iaccino E, Scicchitano S, Lupia M, Chiarella E, Mega T, Bernaudo F, Pelaggi D, Mesuraca M, Pazzaglia S, Semenkow S, Bar EE, Kool M, Pfister S, ... ... Eberhart CG, et al. Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Oncotarget. 4: 1280-92. PMID 23907569 DOI: 10.18632/Oncotarget.1176  0.756
2013 Mao XG, Hütt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 4: 1050-64. PMID 23846349 DOI: 10.18632/Oncotarget.1131  0.495
2013 Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, ... ... Eberhart CG, et al. Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2927-35. PMID 23835706 DOI: 10.1200/Jco.2012.48.5052  0.339
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, ... ... Eberhart CG, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics. 45: 927-32. PMID 23817572 DOI: 10.1038/Ng.2682  0.408
2013 Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, ... ... Eberhart CG, et al. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proceedings of the National Academy of Sciences of the United States of America. 110: 8188-93. PMID 23633565 DOI: 10.1073/Pnas.1300252110  0.383
2013 Chu Q, Orr BA, Semenkow S, Bar EE, Eberhart CG. Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3224-33. PMID 23630166 DOI: 10.1158/1078-0432.Ccr-12-2119  0.783
2013 Meng H, Matthaei M, Ramanan N, Grebe R, Chakravarti S, Speck CL, Kimos M, Vij N, Eberhart CG, Jun AS. L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy. Investigative Ophthalmology & Visual Science. 54: 1887-97. PMID 23422828 DOI: 10.1167/Iovs.12-11021  0.328
2013 Asnaghi L, Handa JT, Merbs SL, Harbour JW, Eberhart CG. A role for Jag2 in promoting uveal melanoma dissemination and growth. Investigative Ophthalmology & Visual Science. 54: 295-306. PMID 23211831 DOI: 10.1167/Iovs.12-10209  0.398
2013 Dubuc AM, Remke M, Korshunov A, Northcott PA, Zhan SH, Mendez-Lago M, Kool M, Jones DT, Unterberger A, Morrissy AS, Shih D, Peacock J, Ramaswamy V, Rolider A, Wang X, ... ... Eberhart CG, et al. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathologica. 125: 373-84. PMID 23184418 DOI: 10.1007/S00401-012-1070-9  0.32
2013 Ho CY, Bar E, Giannini C, Marchionni L, Karajannis MA, Zagzag D, Gutmann DH, Eberhart CG, Rodriguez FJ. MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. Neuro-Oncology. 15: 69-82. PMID 23161775 DOI: 10.1093/Neuonc/Nos269  0.702
2013 Rodriguez FJ, Lim KS, Bowers D, Eberhart CG. Pathological and molecular advances in pediatric low-grade astrocytoma. Annual Review of Pathology. 8: 361-79. PMID 23121055 DOI: 10.1146/Annurev-Pathol-020712-164009  0.389
2013 Aref D, Moffatt CJ, Agnihotri S, Ramaswamy V, Dubuc AM, Northcott PA, Taylor MD, Perry A, Olson JM, Eberhart CG, Croul SE. Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development. Brain Pathology (Zurich, Switzerland). 23: 178-91. PMID 22966790 DOI: 10.1111/J.1750-3639.2012.00631.X  0.443
2013 Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathology (Zurich, Switzerland). 23: 237-43. PMID 22928601 DOI: 10.1111/J.1750-3639.2012.00630.X  0.332
2013 Das CM, Taylor P, Gireud M, Singh A, Lee D, Fuller G, Ji L, Fangusaro J, Rajaram V, Goldman S, Eberhart C, Gopalakrishnan V. The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation. Oncogene. 32: 1691-701. PMID 22665064 DOI: 10.1038/Onc.2012.182  0.408
2013 Ventura B, Yao M, Jiang Y, Wahl K, Rodriguez F, Eberhart CG, Zong H. Abstract PR09: Fine temporal and spatial dissection of medulloblastoma progression with MADM, a mouse genetic mosaic model Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Pr09  0.468
2013 Ahsan SF, Hanaford A, Weingart M, Taylor I, Eberhart C, Raabe E. Abstract 5051: MYC-driven models of primitive neuroectodermal tumor are sensitive to inhibitors of glutamine metabolism. Cancer Research. 73: 5051-5051. DOI: 10.1158/1538-7445.Am2013-5051  0.472
2013 Hutt M, Goldstein W, Nazarian J, Price A, Lim KJ, Warren K, Chang H, Eberhart C, Raabe E. Abstract 5049: Targeting the Notch and mTOR pathways in diffuse intrinsic pontine glioma. Cancer Research. 73: 5049-5049. DOI: 10.1158/1538-7445.Am2013-5049  0.441
2013 Shah S, Hutt M, Karajannis MA, Raabe E, Eberhart CG, Rodriguez FJ. Abstract 5048: mTORC1/mTORC2 signaling in pediatric low grade glioma and pilocytic astrocytoma. Cancer Research. 73: 5048-5048. DOI: 10.1158/1538-7445.Am2013-5048  0.412
2013 Spina R, Filocamo G, Iaccino E, Scicchitano S, Lupia M, Chiarella E, Mega T, Pelaggi D, Mesuraca M, Bar EE, Bond HM, Eberhart CG, Steinkuhler C, Morrone G. Abstract 5045: Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Cancer Research. 73: 5045-5045. DOI: 10.1158/1538-7445.Am2013-5045  0.409
2013 Taylor I, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart C, Raabe EH. Abstract 5044: MYC drives formation of primative neuro-ectodermal tumors in human neural stem cells derived from multiple brain regions. Cancer Research. 73: 5044-5044. DOI: 10.1158/1538-7445.Am2013-5044  0.459
2013 Asnaghi L, Lin MH, Lim KS, Lim KJ, Bar EE, Eberhart CG. Abstract 3776: Hypoxia-inducible factor 1α (HIF1α) has a prometastatic effect in uveal melanoma . Cancer Research. 73: 3776-3776. DOI: 10.1158/1538-7445.Am2013-3776  0.425
2013 Kaur H, Hutt M, Mao X, Eberhart CG, Raabe EH. Abstract 3742: Targeting the stem cell factor HMGA2 to improve outcomes in glioblastoma. Cancer Research. 73: 3742-3742. DOI: 10.1158/1538-7445.Am2013-3742  0.47
2013 Lim KS, Lim KJ, Orr BA, Price AC, Eberhart CG, Bar EE. Abstract 2930: Silencing MCT4 inhibits GBM growth, HIF response, and CD133-positive fraction in a lactate-independent fashion. Cancer Research. 73: 2930-2930. DOI: 10.1158/1538-7445.Am2013-2930  0.458
2013 Ding D, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart C, Raabe E. Abstract 2607: BMI1 and dominant negative p53 cooperate to suppress AKT-mediated oncogene-induced senescence and promote transformation in human neural stem cells. Cancer Research. 73: 2607-2607. DOI: 10.1158/1538-7445.Am2013-2607  0.462
2013 Hanaford AR, Eberhart CG, Raabe EH. Abstract 1872: Targeting MYC-driven medulloblastoma using inhibitors of glutamine metabolism. Cancer Research. 73: 1872-1872. DOI: 10.1158/1538-7445.Am2013-1872  0.422
2013 Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Eberhart C, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174  0.317
2012 Kahlert UD, Bender NO, Maciaczyk D, Bogiel T, Bar EE, Eberhart CG, Nikkhah G, Maciaczyk J. CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated glioblastoma multiforme-derived cell line with a PNET-like component. Folia Neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences. 50: 357-68. PMID 23319191 DOI: 10.5114/Fn.2012.32365  0.737
2012 Raabe EH, Eberhart CG. Methylome alterations "mark" new therapeutic opportunities in glioblastoma. Cancer Cell. 22: 417-8. PMID 23079650 DOI: 10.1016/J.Ccr.2012.10.001  0.336
2012 Grossman R, Tyler B, Brem H, Eberhart CG, Wang S, Fu DX, Wen Z, Zhou J. Growth properties of SF188/V+ human glioma in rats in vivo observed by magnetic resonance imaging. Journal of Neuro-Oncology. 110: 315-23. PMID 23011120 DOI: 10.1007/S11060-012-0974-5  0.359
2012 Bai RY, Staedtke V, Lidov HG, Eberhart CG, Riggins GJ. OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells. Cancer Research. 72: 5988-6001. PMID 22986744 DOI: 10.1158/0008-5472.Can-12-0614  0.387
2012 Rodriguez FJ, Perry A, Rosenblum MK, Krawitz S, Cohen KJ, Lin D, Mosier S, Lin MT, Eberhart CG, Burger PC. Disseminated oligodendroglial-like leptomeningeal tumor of childhood: a distinctive clinicopathologic entity. Acta Neuropathologica. 124: 627-41. PMID 22941225 DOI: 10.1007/S00401-012-1037-X  0.376
2012 Rodriguez FJ, Ligon AH, Horkayne-Szakaly I, Rushing EJ, Ligon KL, Vena N, Garcia DI, Cameron JD, Eberhart CG. BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper. Journal of Neuropathology and Experimental Neurology. 71: 789-94. PMID 22892521 DOI: 10.1097/Nen.0B013E3182656Ef8  0.362
2012 Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Eberhart CG, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327  0.329
2012 Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. Plos One. 7: e41036. PMID 22829908 DOI: 10.1371/Journal.Pone.0041036  0.446
2012 Lim KJ, Rajan K, Eberhart CG. Effects of Zeng Sheng Ping/ACAPHA on malignant brain tumor growth and Notch signaling. Anticancer Research. 32: 2689-96. PMID 22753727  0.39
2012 Li M, Lockwood W, Zielenska M, Northcott P, Ra YS, Bouffet E, Yoshimoto M, Rutka JT, Yan H, Taylor MD, Eberhart C, Hawkins CE, Lam W, Squire JA, Huang A. Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor. Cancer Genetics. 205: 220-31. PMID 22682621 DOI: 10.1016/J.Cancergen.2012.03.002  0.444
2012 Kahlert UD, Maciaczyk D, Doostkam S, Orr BA, Simons B, Bogiel T, Reithmeier T, Prinz M, Schubert J, Niedermann G, Brabletz T, Eberhart CG, Nikkhah G, Maciaczyk J. Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition. Cancer Letters. 325: 42-53. PMID 22652173 DOI: 10.1016/J.Canlet.2012.05.024  0.437
2012 Orr BA, Eberhart CG. Nature versus nurture in glioblastoma: microenvironment and genetics can both drive mesenchymal transcriptional signature. The American Journal of Pathology. 180: 1768-71. PMID 22449951 DOI: 10.1016/J.Ajpath.2012.03.001  0.404
2012 Dubuc AM, Morrissy AS, Kloosterhof NK, Northcott PA, Yu EP, Shih D, Peacock J, Grajkowska W, van Meter T, Eberhart CG, Pfister S, Marra MA, Weiss WA, Scherer SW, Rutka JT, et al. Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathologica. 123: 485-99. PMID 22358458 DOI: 10.1007/S00401-012-0959-7  0.324
2012 Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, et al. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature. 482: 529-33. PMID 22343890 DOI: 10.1038/Nature10825  0.305
2012 Rodriguez FJ, Orr BA, Ligon KL, Eberhart CG. Neoplastic cells are a rare component in human glioblastoma microvasculature. Oncotarget. 3: 98-106. PMID 22298889 DOI: 10.18632/Oncotarget.427  0.427
2012 Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG. Notch signaling promotes growth and invasion in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 654-65. PMID 22228632 DOI: 10.1158/1078-0432.Ccr-11-1406  0.766
2012 Lin A, Rodriguez FJ, Karajannis MA, Williams SC, Legault G, Zagzag D, Burger PC, Allen JC, Eberhart CG, Bar EE. BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants. Journal of Neuropathology and Experimental Neurology. 71: 66-72. PMID 22157620 DOI: 10.1097/Nen.0B013E31823F2Cb0  0.759
2012 Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathologica. 123: 465-72. PMID 22134537 DOI: 10.1007/S00401-011-0922-Z  0.301
2012 Northcott PA, Shih DJ, Remke M, Cho YJ, Kool M, Hawkins C, Eberhart CG, Dubuc A, Guettouche T, Cardentey Y, Bouffet E, Pomeroy SL, Marra M, Malkin D, Rutka JT, et al. Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathologica. 123: 615-26. PMID 22057785 DOI: 10.1007/S00401-011-0899-7  0.301
2012 Lim KS, Lim KJ, Orr BA, Price AC, Eberhart CG, Bar EE. Abstract 3483: Inhibition of Monocarboxylate Transporter 4 (MCT4) targets stem-like cells in glioblastoma Cancer Research. 72: 3483-3483. DOI: 10.1158/1538-7445.Am2012-3483  0.467
2012 Lim KJ, Eberhart CG, Bar EE. Abstract 3335: The potential role of lateral inhibition in the maintenance of glioblastoma cancer stem cells Cancer Research. 72: 3335-3335. DOI: 10.1158/1538-7445.Am2012-3335  0.454
2012 Hutt M, Lim KJ, Warren K, Chang HT, Eberhart CG, Raabe EH. Abstract 2480: High-level activation of the Notch pathway in diffuse intrinsic pontine glioma Cancer Research. 72: 2480-2480. DOI: 10.1158/1538-7445.Am2012-2480  0.5
2012 Kozono D, Nitta M, Sampetrean O, Kimberly N, Kushwaha D, Merzon D, Ligon K, Zhu S, Zhu K, Kim TH, Kwon C, Becher O, Saya H, Chen CC, Donovan LK, ... ... Eberhart CG, et al. LAB-STEM CELLS Neuro-Oncology. 14: vi142-vi152. DOI: 10.1093/Neuonc/Nos239  0.716
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Eberhart CG, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.317
2011 Ma B, Sen T, Asnaghi L, Valapala M, Yang F, Hose S, McLeod DS, Lu Y, Eberhart C, Zigler JS, Sinha D. βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis. Cell Death & Disease. 2: e217. PMID 21993393 DOI: 10.1038/Cddis.2011.100  0.324
2011 Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, et al. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. The American Journal of Pathology. 179: 1608-15. PMID 21888887 DOI: 10.1016/J.Ajpath.2011.06.018  0.376
2011 Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/Science.1207313  0.371
2011 Orr BA, Bai H, Odia Y, Jain D, Anders RA, Eberhart CG. Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth. Journal of Neuropathology and Experimental Neurology. 70: 568-77. PMID 21666501 DOI: 10.1097/Nen.0B013E31821Ff8D8  0.437
2011 Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3590-9. PMID 21636552 DOI: 10.1158/1078-0432.Ccr-10-3349  0.781
2011 Li Y, Li A, Glas M, Lal B, Ying M, Sang Y, Xia S, Trageser D, Guerrero-Cázares H, Eberhart CG, Quiñones-Hinojosa A, Scheffler B, Laterra J. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proceedings of the National Academy of Sciences of the United States of America. 108: 9951-6. PMID 21628563 DOI: 10.1073/Pnas.1016912108  0.407
2011 Ying M, Sang Y, Li Y, Guerrero-Cazares H, Quinones-Hinojosa A, Vescovi AL, Eberhart CG, Xia S, Laterra J. Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells. Stem Cells (Dayton, Ohio). 29: 20-31. PMID 21280156 DOI: 10.1002/Stem.561  0.469
2011 Pierfelice TJ, Schreck KC, Dang L, Asnaghi L, Gaiano N, Eberhart CG. Notch3 activation promotes invasive glioma formation in a tissue site-specific manner. Cancer Research. 71: 1115-25. PMID 21245095 DOI: 10.1158/0008-5472.Can-10-0690  0.401
2011 Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biology & Therapy. 11: 464-73. PMID 21193839 DOI: 10.4161/Cbt.11.5.14410  0.777
2011 Eberhart CG. Molecular diagnostics in embryonal brain tumors. Brain Pathology (Zurich, Switzerland). 21: 96-104. PMID 21129063 DOI: 10.1111/J.1750-3639.2010.00455.X  0.434
2011 Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1424-30. PMID 21098324 DOI: 10.1200/Jco.2010.28.5148  0.346
2011 Shahi MH, Afzal M, Sinha S, Eberhart CG, Rey JA, Fan X, Castresana JS. Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples. Journal of Neuro-Oncology. 103: 287-96. PMID 20853133 DOI: 10.1007/S11060-010-0401-8  0.421
2011 Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P, Rutka JT, Pfister S, Taylor MD. Medulloblastoma comprises four distinct molecular variants. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1408-14. PMID 20823417 DOI: 10.1200/Jco.2009.27.4324  0.33
2011 Lim KS, Bar EE, Raabe EH, Jain D, Eberhart CG. Abstract 3459: Expression of oncogene-induced senescence markers in pilocytic astrocytomaIs associated with younger age and longer survival Cancer Research. 71: 3459-3459. DOI: 10.1158/1538-7445.Am2011-3459  0.425
2011 Mao X, Raabe EH, Maciaczyk J, Kahlert U, Nikkhah G, Eberhart CG. Abstract 3454: LIN28 is expressed in glioblastomas and promotes KRAS-mediated transformation of human neural stem cells Cancer Research. 71: 3454-3454. DOI: 10.1158/1538-7445.Am2011-3454  0.424
2011 Raabe EH, Lim KS, Mao X, Bar E, Meeker A, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG. Abstract 3303: BRAF activation induces cellular transformation and senescence and down-regulates SOX2 in human neural stem cells: a model of pilocytic astrocytoma Cancer Research. 71: 3303-3303. DOI: 10.1158/1538-7445.Am2011-3303  0.769
2011 Ying M, Sang Y, Li Y, Guerrero-Cazares H, Quinones-Hinojosa A, Vescovi AL, Eberhart CG, Xia S, Laterra J. Abstract 3296: KLF9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells Cancer Research. 71: 3296-3296. DOI: 10.1158/1538-7445.Am2011-3296  0.483
2011 Kahlert U, Maciaczyk D, Nikkhah G, Simons B, Orr B, Eberhart C, Maciaczyk J. Abstract 2903: The role of canonical WNT/β-catenin signaling in glial tumors Cancer Research. 71: 2903-2903. DOI: 10.1158/1538-7445.Am2011-2903  0.379
2011 Asnaghi L, Coonfield ML, Schreck KC, Bar EE, Handa J, Merbs S, Ebrahimi KB, Harbour JW, Eberhart CG. Abstract 1415: The Notch ligand Jag 2 promotes growth and invasion in uveal melanoma cells Cancer Research. 71: 1415-1415. DOI: 10.1158/1538-7445.Am2011-1415  0.434
2010 Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 6060-70. PMID 21169257 DOI: 10.1158/1078-0432.Ccr-10-1624  0.782
2010 Shahi MH, Afzal M, Sinha S, Eberhart CG, Rey JA, Fan X, Castresana JS. Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma. Bmc Cancer. 10: 614. PMID 21059263 DOI: 10.1186/1471-2407-10-614  0.431
2010 Pfister SM, Korshunov A, Kool M, Hasselblatt M, Eberhart C, Taylor MD. Molecular diagnostics of CNS embryonal tumors. Acta Neuropathologica. 120: 553-66. PMID 20882288 DOI: 10.1007/S00401-010-0751-5  0.448
2010 Bar EE, Lin A, Mahairaki V, Matsui W, Eberhart CG. Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. The American Journal of Pathology. 177: 1491-502. PMID 20671264 DOI: 10.2353/Ajpath.2010.091021  0.767
2010 Siu IM, Tyler BM, Chen JX, Eberhart CG, Thomale UW, Olivi A, Jallo GI, Riggins GJ, Gallia GL. Establishment of a human glioblastoma stemlike brainstem rodent tumor model. Journal of Neurosurgery. Pediatrics. 6: 92-7. PMID 20593994 DOI: 10.3171/2010.3.Peds09366  0.386
2010 Yustein JT, Liu YC, Gao P, Jie C, Le A, Vuica-Ross M, Chng WJ, Eberhart CG, Bergsagel PL, Dang CV. Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model. Proceedings of the National Academy of Sciences of the United States of America. 107: 3534-9. PMID 20133585 DOI: 10.1073/Pnas.0901230107  0.443
2010 Nakahara Y, Northcott PA, Li M, Kongkham PN, Smith C, Yan H, Croul S, Ra YS, Eberhart C, Huang A, Bigner D, Grajkowska W, Van Meter T, Rutka JT, Taylor MD. Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia (New York, N.Y.). 12: 20-7. PMID 20072650 DOI: 10.1593/Neo.91122  0.415
2010 Raabe EH, Eberhart CG. High-risk medulloblastoma: does c-myc amplification overrule histopathology? Pediatric Blood & Cancer. 54: 344-5. PMID 20063409 DOI: 10.1002/Pbc.22398  0.38
2010 Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells (Dayton, Ohio). 28: 5-16. PMID 19904829 DOI: 10.1002/Stem.254  0.506
2010 Shahi MH, Fan X, Sinha S, Afzal M, Eberhart C, Castresana JS. Abstract 5150: Differential epigenetic regulation of sonic hedgehog GLI1 on downstream target genes in medulloblastoma and astrocytomas Cancer Research. 70: 5150-5150. DOI: 10.1158/1538-7445.Am10-5150  0.394
2010 Lim KJ, Maitra A, Bisht S, Eberhart C, Bar E. Abstract 4440: Using nanocurcumin to treat medulloblastoma and glioblastoma Cancer Research. 70: 4440-4440. DOI: 10.1158/1538-7445.Am10-4440  0.783
2010 Raabe EH, Maciaczyk J, Kahlert U, Nikkhah G, Eberhart C. Abstract 4352: Using human neural stem cells to model pediatric high grade gliomas: The role of p53, c-myc, and EGFRvIII in neoplastic transformation Cancer Research. 70: 4352-4352. DOI: 10.1158/1538-7445.Am10-4352  0.452
2010 Wu X, Collier L, Northcott P, Dubuc A, Eberhart C, Meter TV, Zagzag D, Croul S, Dupuy A, Scheetz TE, Scherer S, Bouffet E, Weiss WA, Largaespada DAD, Taylor MD. Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease Cancer Research. 70: 4350-4350. DOI: 10.1158/1538-7445.Am10-4350  0.403
2010 Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart C, Mack S, Bouffet E, Clifford SC, Hawkins C, French P, Rutka JT, Pfister S, Taylor MD. Abstract 4347: Medulloblastoma comprises four distinct diseases Cancer Research. 70: 4347-4347. DOI: 10.1158/1538-7445.Am10-4347  0.382
2010 Li Y, Lal B, Cázares HG, Quinones-Hinjosa A, Eberhart C, Laterra J. Abstract 4285: C-Met signaling supports a stem-like transcriptional program and phenotype in glioblastoma Cancer Research. 70: 4285-4285. DOI: 10.1158/1538-7445.Am10-4285  0.458
2010 Asnaghi L, Coonfield ML, Schreck KC, Bar EE, Handa J, Merbs S, Ebrahimi K, Harbour JW, Eberhart CG. Abstract 4141: Notch signaling: A new potential target in the treatment of uveal melanoma Cancer Research. 70: 4141-4141. DOI: 10.1158/1538-7445.Am10-4141  0.436
2010 Schreck KC, Taylor P, Bar EE, Gopalakrishnan V, Gaiano N, Eberhart CG. Abstract 14: Targeting Notch in malignant brain tumors: Crosstalk with Hedgehog as a potential mechanism of treatment resistance Cancer Research. 70: 14-14. DOI: 10.1158/1538-7445.Am10-14  0.483
2010 Li M, Lee KF, Lu Y, Clarke I, Shih D, Eberhart C, Peter Collins V, Van Meter T, Picard D, Zhou L, Boutros P, Modena P, Liang ML, Scherer SW, Bouffet E, et al. Frequent Amplification of a chr19q13.41 MicroRNA Polycistron in Aggressive Primitive Neuroectodermal Brain Tumors (DOI:10.1016/j.ccr.2009.10.025) Cancer Cell. 17: 413. DOI: 10.1016/J.Ccr.2010.03.016  0.373
2009 Li M, Lee KF, Lu Y, Clarke I, Shih D, Eberhart C, Collins VP, Van Meter T, Picard D, Zhou L, Boutros PC, Modena P, Liang ML, Scherer SW, Bouffet E, et al. Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell. 16: 533-46. PMID 19962671 DOI: 10.1016/J.Ccr.2009.10.025  0.382
2009 Ayres B, Miller NR, Eberhart CG, Dibernardo CW. Ultrasound features of orbital granular cell tumor. Ophthalmic Plastic and Reconstructive Surgery. 25: 320-2. PMID 19617798 DOI: 10.1097/Iop.0B013E3181Aad8E0  0.389
2009 Nasonkin I, Mahairaki V, Xu L, Hatfield G, Cummings BJ, Eberhart C, Ryugo DK, Maric D, Bar E, Koliatsos VE. Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells (Dayton, Ohio). 27: 2414-26. PMID 19609935 DOI: 10.1002/Stem.177  0.72
2009 Sun P, Xia S, Lal B, Eberhart CG, Quinones-Hinojosa A, Maciaczyk J, Matsui W, Dimeco F, Piccirillo SM, Vescovi AL, Laterra J. DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation. Stem Cells (Dayton, Ohio). 27: 1473-86. PMID 19544453 DOI: 10.1002/Stem.89  0.488
2009 Northcott PA, Nakahara Y, Wu X, Feuk L, Ellison DW, Croul S, Mack S, Kongkham PN, Peacock J, Dubuc A, Ra YS, Zilberberg K, McLeod J, Scherer SW, Sunil Rao J, ... Eberhart CG, et al. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nature Genetics. 41: 465-72. PMID 19270706 DOI: 10.1038/Ng.336  0.334
2009 Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G. Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2291-301. PMID 19258443 DOI: 10.1158/1078-0432.Ccr-08-2004  0.391
2009 von Bueren AO, Shalaby T, Oehler-Jänne C, Arnold L, Stearns D, Eberhart CG, Arcaro A, Pruschy M, Grotzer MA. RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells. Bmc Cancer. 9: 10. PMID 19134217 DOI: 10.1186/1471-2407-9-10  0.381
2009 Barnes M, Eberhart CG, Collins R, Tihan T. Expression of p75NTR in fetal brain and medulloblastomas: evidence of a precursor cell marker and its persistence in neoplasia. Journal of Neuro-Oncology. 92: 193-201. PMID 19066726 DOI: 10.1007/S11060-008-9755-6  0.402
2009 Gessi M, Giangaspero F, Lauriola L, Gardiman M, Scheithauer BW, Halliday W, Hawkins C, Rosenblum MK, Burger PC, Eberhart CG. Embryonal tumors with abundant neuropil and true rosettes: a distinctive CNS primitive neuroectodermal tumor. The American Journal of Surgical Pathology. 33: 211-7. PMID 18987548 DOI: 10.1097/Pas.0B013E318186235B  0.399
2008 Pierfelice TJ, Schreck KC, Eberhart CG, Gaiano N. Notch, neural stem cells, and brain tumors. Cold Spring Harbor Symposia On Quantitative Biology. 73: 367-75. PMID 19022772 DOI: 10.1101/Sqb.2008.73.013  0.434
2008 Rodriguez FJ, Giannini C, Asmann YW, Sharma MK, Perry A, Tibbetts KM, Jenkins RB, Scheithauer BW, Anant S, Jenkins S, Eberhart CG, Sarkaria JN, Gutmann DH. Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes. Journal of Neuropathology and Experimental Neurology. 67: 1194-204. PMID 19018242 DOI: 10.1097/Nen.0B013E31818Fbe1E  0.315
2008 Briggs KJ, Eberhart CG, Watkins DN. Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction. Cancer Research. 68: 8654-6. PMID 18974104 DOI: 10.1158/0008-5472.Can-08-1904  0.418
2008 Yi JM, Tsai HC, Glöckner SC, Lin S, Ohm JE, Easwaran H, James CD, Costello JF, Riggins G, Eberhart CG, Laterra J, Vescovi AL, Ahuja N, Herman JG, Schuebel KE, et al. Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Research. 68: 8094-103. PMID 18829568 DOI: 10.1158/0008-5472.Can-07-6208  0.36
2008 Binning MJ, Niazi T, Pedone CA, Lal B, Eberhart CG, Kim KJ, Laterra J, Fults DW. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth. Cancer Research. 68: 7838-45. PMID 18829539 DOI: 10.1158/0008-5472.Can-08-1899  0.464
2008 Bar EE, Lin A, Tihan T, Burger PC, Eberhart CG. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. Journal of Neuropathology and Experimental Neurology. 67: 878-87. PMID 18716556 DOI: 10.1097/Nen.0B013E3181845622  0.728
2008 Siu IM, Bai R, Gallia GL, Edwards JB, Tyler BM, Eberhart CG, Riggins GJ. Coexpression of neuronatin splice forms promotes medulloblastoma growth. Neuro-Oncology. 10: 716-24. PMID 18701710 DOI: 10.1215/15228517-2008-038  0.401
2008 Eberhart CG. Even cancers want commitment: lineage identity and medulloblastoma formation. Cancer Cell. 14: 105-7. PMID 18691544 DOI: 10.1016/J.Ccr.2008.07.011  0.339
2008 Fan X, Eberhart CG. Medulloblastoma stem cells. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2821-7. PMID 18539960 DOI: 10.1200/Jco.2007.15.2264  0.46
2008 Briggs KJ, Corcoran-Schwartz IM, Zhang W, Harcke T, Devereux WL, Baylin SB, Eberhart CG, Watkins DN. Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. Genes & Development. 22: 770-85. PMID 18347096 DOI: 10.1101/Gad.1640908  0.465
2008 Hatton BA, Villavicencio EH, Tsuchiya KD, Pritchard JI, Ditzler S, Pullar B, Hansen S, Knoblaugh SE, Lee D, Eberhart CG, Hallahan AR, Olson JM. The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread. Cancer Research. 68: 1768-76. PMID 18339857 DOI: 10.1158/0008-5472.Can-07-5092  0.399
2008 Li Y, Guessous F, Johnson EB, Eberhart CG, Li XN, Shu Q, Fan S, Lal B, Laterra J, Schiff D, Abounader R. Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 98-111. PMID 18059365 DOI: 10.1038/Labinvest.3700702  0.343
2007 Lo KC, Ma C, Bundy BN, Pomeroy SL, Eberhart CG, Cowell JK. Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7022-8. PMID 18056178 DOI: 10.1158/1078-0432.Ccr-07-1420  0.345
2007 Li T, Wen H, Brayton C, Das P, Smithson LA, Fauq A, Fan X, Crain BJ, Price DL, Golde TE, Eberhart CG, Wong PC. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase. The Journal of Biological Chemistry. 282: 32264-73. PMID 17827153 DOI: 10.1074/Jbc.M703649200  0.38
2007 Bar EE, Chaudhry A, Lin A, Fan X, Schreck K, Matsui W, Piccirillo S, Vescovi AL, DiMeco F, Olivi A, Eberhart CG. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells (Dayton, Ohio). 25: 2524-33. PMID 17628016 DOI: 10.1634/Stemcells.2007-0166  0.78
2007 Lo KC, Rossi MR, Eberhart CG, Cowell JK. Genome wide copy number abnormalities in pediatric medulloblastomas as assessed by array comparative genome hybridization. Brain Pathology (Zurich, Switzerland). 17: 282-96. PMID 17465989 DOI: 10.1111/J.1750-3639.2007.00072.X  0.309
2007 von Bueren AO, Shalaby T, Rajtarova J, Stearns D, Eberhart CG, Helson L, Arcaro A, Grotzer MA. Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells. Bmc Cancer. 7: 19. PMID 17254356 DOI: 10.1186/1471-2407-7-19  0.424
2007 Eberhart CG. In search of the medulloblast: neural stem cells and embryonal brain tumors. Neurosurgery Clinics of North America. 18: 59-69, viii-ix. PMID 17244554 DOI: 10.1016/J.Nec.2006.10.005  0.458
2007 Bar EE, Chaudhry A, Farah MH, Eberhart CG. Hedgehog signaling promotes medulloblastoma survival via Bc/II. The American Journal of Pathology. 170: 347-55. PMID 17200206 DOI: 10.2353/Ajpath.2007.060066  0.755
2006 Gallia GL, Rand V, Siu IM, Eberhart CG, James CD, Marie SK, Oba-Shinjo SM, Carlotti CG, Caballero OL, Simpson AJ, Brock MV, Massion PP, Carson BS, Riggins GJ. PIK3CA gene mutations in pediatric and adult glioblastoma multiforme. Molecular Cancer Research : McR. 4: 709-14. PMID 17050665 DOI: 10.1158/1541-7786.Mcr-06-0172  0.311
2006 Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, Eberhart CG. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Research. 66: 7445-52. PMID 16885340 DOI: 10.1158/0008-5472.Can-06-0858  0.494
2006 Chu LC, Eberhart CG, Grossman SA, Herman JG. Epigenetic silencing of multiple genes in primary CNS lymphoma. International Journal of Cancer. Journal International Du Cancer. 119: 2487-91. PMID 16858686 DOI: 10.1002/Ijc.22124  0.34
2006 Park JT, Li M, Nakayama K, Mao TL, Davidson B, Zhang Z, Kurman RJ, Eberhart CG, Shih IeM, Wang TL. Notch3 gene amplification in ovarian cancer. Cancer Research. 66: 6312-8. PMID 16778208 DOI: 10.1158/0008-5472.Can-05-3610  0.432
2006 Dixit VD, Weeraratna AT, Yang H, Bertak D, Cooper-Jenkins A, Riggins GJ, Eberhart CG, Taub DD. Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility. The Journal of Biological Chemistry. 281: 16681-90. PMID 16527811 DOI: 10.1074/Jbc.M600223200  0.38
2006 Su X, Gopalakrishnan V, Stearns D, Aldape K, Lang FF, Fuller G, Snyder E, Eberhart CG, Majumder S. Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Molecular and Cellular Biology. 26: 1666-78. PMID 16478988 DOI: 10.1128/Mcb.26.5.1666-1678.2006  0.436
2006 Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG. c-myc overexpression causes anaplasia in medulloblastoma. Cancer Research. 66: 673-81. PMID 16423996 DOI: 10.1158/0008-5472.Can-05-1580  0.383
2006 Dang L, Fan X, Chaudhry A, Wang M, Gaiano N, Eberhart CG. Notch3 signaling initiates choroid plexus tumor formation. Oncogene. 25: 487-91. PMID 16186803 DOI: 10.1038/Sj.Onc.1209074  0.438
2005 Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, et al. The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes & Development. 19: 2656-67. PMID 16260494 DOI: 10.1101/Gad.1368605  0.419
2005 Li Y, Lal B, Kwon S, Fan X, Saldanha U, Reznik TE, Kuchner EB, Eberhart C, Laterra J, Abounader R. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy. Cancer Research. 65: 9355-62. PMID 16230398 DOI: 10.1158/0008-5472.Can-05-1946  0.466
2005 Abel TW, Baker SJ, Fraser MM, Tihan T, Nelson JS, Yachnis AT, Bouffard JP, Mena H, Burger PC, Eberhart CG. Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway. Journal of Neuropathology and Experimental Neurology. 64: 341-9. PMID 15835270 DOI: 10.1093/Jnen/64.4.341  0.38
2005 Purow BW, Haque RM, Noel MW, Su Q, Burdick MJ, Lee J, Sundaresan T, Pastorino S, Park JK, Mikolaenko I, Maric D, Eberhart CG, Fine HA. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Research. 65: 2353-63. PMID 15781650 DOI: 10.1158/0008-5472.Can-04-1890  0.436
2005 Eberhart CG, Chaudhry A, Daniel RW, Khaki L, Shah KV, Gravitt PE. Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus. Bmc Cancer. 5: 19. PMID 15717928 DOI: 10.1186/1471-2407-5-19  0.336
2004 Fan X, Mikolaenko I, Elhassan I, Ni X, Wang Y, Ball D, Brat DJ, Perry A, Eberhart CG. Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Research. 64: 7787-93. PMID 15520184 DOI: 10.1158/0008-5472.Can-04-1446  0.491
2004 Boon K, Edwards JB, Eberhart CG, Riggins GJ. Identification of astrocytoma associated genes including cell surface markers. Bmc Cancer. 4: 39. PMID 15265232 DOI: 10.1186/1471-2407-4-39  0.357
2004 Eberhart CG, Kratz J, Wang Y, Summers K, Stearns D, Cohen K, Dang CV, Burger PC. Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia. Journal of Neuropathology and Experimental Neurology. 63: 441-9. PMID 15198123 DOI: 10.1093/Jnen/63.5.441  0.383
2004 Fisher PG, Burger PC, Eberhart CG. Biologic risk stratification of medulloblastoma: the real time is now. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 971-4. PMID 14970187 DOI: 10.1200/Jco.2004.12.939  0.362
2003 Parwani AV, Mikolaenko I, Eberhart CG, Burger PC, Rosenthal DL, Ali SZ. Rhabdoid meningioma: cytopathologic findings in cerebrospinal fluid. Diagnostic Cytopathology. 29: 297-9. PMID 14595800 DOI: 10.1002/Dc.10374  0.401
2003 Boon K, Edwards JB, Siu IM, Olschner D, Eberhart CG, Marra MA, Strausberg RL, Riggins GJ. Comparison of medulloblastoma and normal neural transcriptomes identifies a restricted set of activated genes. Oncogene. 22: 7687-94. PMID 14576832 DOI: 10.1038/Sj.Onc.1207043  0.371
2003 Eberhart CG, Burger PC. Anaplasia and grading in medulloblastomas. Brain Pathology (Zurich, Switzerland). 13: 376-85. PMID 12946027 DOI: 10.1111/J.1750-3639.2003.Tb00037.X  0.359
2003 Fan X, Wang Y, Kratz J, Brat DJ, Robitaille Y, Moghrabi A, Perlman EJ, Dang CV, Burger PC, Eberhart CG. hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors. The American Journal of Pathology. 162: 1763-9. PMID 12759234 DOI: 10.1016/S0002-9440(10)64311-8  0.408
2003 Eberhart CG, Cohen KJ, Tihan T, Goldthwaite PT, Burger PC. Medulloblastomas with systemic metastases: evaluation of tumor histopathology and clinical behavior in 23 patients. Journal of Pediatric Hematology/Oncology. 25: 198-203. PMID 12621237 DOI: 10.1097/00043426-200303000-00004  0.306
2003 Eberhart CG. Medulloblastoma in mice lacking p53 and PARP: all roads lead to Gli. The American Journal of Pathology. 162: 7-10. PMID 12507884 DOI: 10.1016/S0002-9440(10)63792-3  0.465
2002 Kratz JE, Stearns D, Huso DL, Slunt HH, Price DL, Borchelt DR, Eberhart CG. Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation. Bmc Cancer. 2: 33. PMID 12460454 DOI: 10.1186/1471-2407-2-33  0.351
2002 Berman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science (New York, N.Y.). 297: 1559-61. PMID 12202832 DOI: 10.1126/Science.1073733  0.484
2002 Liu JM, Garonzik IM, Eberhart CG, Sampath P, Brem H. Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report. Neurosurgery. 50: 639-44; discussion 6. PMID 11841735 DOI: 10.1097/00006123-200203000-00041  0.302
2002 Eberhart CG, Kratz JE, Schuster A, Goldthwaite P, Cohen KJ, Perlman EJ, Burger PC. Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas. Brain Pathology (Zurich, Switzerland). 12: 36-44. PMID 11770900 DOI: 10.1111/J.1750-3639.2002.Tb00420.X  0.316
2001 Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nature Genetics. 29: 404-11. PMID 11726927 DOI: 10.1038/Ng781  0.334
2001 Eberhart CG, Morrison A, Gyure KA, Frazier J, Smialek JE, Troncoso JC. Decreasing incidence of sudden death due to undiagnosed primary central nervous system tumors. Archives of Pathology & Laboratory Medicine. 125: 1024-30. PMID 11473451 DOI: 10.1043/0003-9985(2001)125<1024:Diosdd>2.0.Co;2  0.358
2001 Eberhart CG, Kaufman WE, Tihan T, Burger PC. Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules. Journal of Neuropathology and Experimental Neurology. 60: 462-9. PMID 11379821 DOI: 10.1093/Jnen/60.5.462  0.362
2000 Czader M, Eberhart CG, Bhatti N, Cummings C, Westra WH. Metastasizing mixed tumor of the parotid: initial presentation as a solitary kidney tumor and ultimate carcinomatous transformation at the primary site. The American Journal of Surgical Pathology. 24: 1159-64. PMID 10935658 DOI: 10.1097/00000478-200008000-00015  0.374
2000 Eberhart CG, Brat DJ, Cohen KJ, Burger PC. Pediatric neuroblastic brain tumors containing abundant neuropil and true rosettes. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 3: 346-52. PMID 10890250 DOI: 10.1007/S100249910049  0.403
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