| Year |
Citation |
Score |
| 2024 |
Tuddenham JF, Taga M, Haage V, Marshe VS, Roostaei T, White C, Lee AJ, Fujita M, Khairallah A, Zhang Y, Green G, Hyman B, Frosch M, Hopp S, Beach TG, et al. A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states. Nature Neuroscience. PMID 39406950 DOI: 10.1038/s41593-024-01764-7 |
0.408 |
|
| 2024 |
Gazula H, Tregidgo HFJ, Billot B, Balbastre Y, Williams-Ramirez J, Herisse R, Deden-Binder LJ, Casamitjana A, Melief EJ, Latimer CS, Kilgore MD, Montine M, Robinson E, Blackburn E, Marshall MS, ... ... Frosch MP, et al. Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology. Elife. 12. PMID 38896568 DOI: 10.7554/eLife.91398 |
0.695 |
|
| 2024 |
Oakley DH, Chung M, Abrha S, Hyman BT, Frosch MP. β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains. Journal of Neuropathology and Experimental Neurology. PMID 38874454 DOI: 10.1093/jnen/nlae053 |
0.739 |
|
| 2024 |
Levin J, Baiardi S, Quadalti C, Rossi M, Mammana A, Vöglein J, Bernhardt A, Perrin RJ, Jucker M, Preische O, Hofmann A, Höglinger GU, Cairns NJ, Franklin EE, Chrem P, ... ... Frosch MP, et al. α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38666355 DOI: 10.1002/alz.13818 |
0.329 |
|
| 2024 |
Wachter A, Woodbury ME, Lombardo S, Abdourahman A, Wuest C, McGlame E, Pastika T, Tamm J, Romanul N, Yanamandra K, Bennett R, Lin G, Kwon T, Liao F, Klein C, ... ... Frosch MP, et al. Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau. Acta Neuropathologica. 147: 65. PMID 38557897 DOI: 10.1007/s00401-024-02704-2 |
0.495 |
|
| 2024 |
Greenberg ABW, Mekbib KY, Mehta NH, Kiziltug E, Duy PQ, Smith HR, Junkkari A, Leinonen V, Hyman BT, Chan D, Curry WT, Arnold SE, Barker Ii FG, Frosch MP, Kahle KT. Utility of cortical tissue analysis in normal pressure hydrocephalus. Cerebral Cortex (New York, N.Y. : 1991). PMID 38275188 DOI: 10.1093/cercor/bhae001 |
0.375 |
|
| 2023 |
Greenberg ABW, Mehta NH, Mekbib KY, Kiziltug E, Smith HR, Hyman BT, Chan D, Curry WT, Arnold SE, Frosch MP, Duy PQ, Kahle KT. Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis. Cerebral Cortex (New York, N.Y. : 1991). PMID 37814356 DOI: 10.1093/cercor/bhad374 |
0.363 |
|
| 2023 |
Mate de Gerando A, Quittot N, Frosch MP, Hyman BT. Reply: Soluble oligomers or insoluble fibrils? Acta Neuropathologica. 146: 863-866. PMID 37733036 DOI: 10.1007/s00401-023-02634-5 |
0.339 |
|
| 2023 |
Sepulveda-Falla D, Villegas Lanau CA, White C, Serrano GE, Acosta-Uribe J, Mejía-Cupajita B, Villalba-Moreno ND, Lu P, Glatzel M, Kofler JK, Ghetti B, Frosch MP, Lopera Restrepo F, Kosik KS, Beach TG. Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes. Medrxiv : the Preprint Server For Health Sciences. PMID 37646002 DOI: 10.1101/2023.08.14.23294081 |
0.307 |
|
| 2023 |
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Frosch MP, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311 |
0.399 |
|
| 2023 |
Gazula H, Tregidgo HFJ, Billot B, Balbastre Y, William-Ramirez J, Herisse R, Casamitjana A, Melief EJ, Latimer CS, Kilgore MD, Montine M, Robinson E, Blackburn E, Marshall MS, Connors TR, ... ... Frosch MP, et al. 3D analysis of dissection photographs with surface scanning and machine learning for quantitative neuropathology. Biorxiv : the Preprint Server For Biology. PMID 37333251 DOI: 10.1101/2023.06.08.544050 |
0.691 |
|
| 2023 |
Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, ... ... Frosch MP, et al. Creating the Pick's disease International Consortium: Association study of H2 haplotype with risk of Pick's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37163045 DOI: 10.1101/2023.04.17.23288471 |
0.682 |
|
| 2023 |
Merrihew GE, Park J, Plubell D, Searle BC, Keene CD, Larson EB, Bateman R, Perrin RJ, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Montine TJ, et al. A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease. Scientific Data. 10: 206. PMID 37059743 DOI: 10.1038/s41597-023-02057-7 |
0.313 |
|
| 2023 |
Kivisäkk P, Carlyle BC, Sweeney T, Trombetta BA, LaCasse K, El-Mufti L, Tuncali I, Chibnik LB, Das S, Scherzer CR, Johnson KA, Dickerson BC, Gomez-Isla T, Blacker D, Oakley DH, ... Frosch MP, et al. Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment. Frontiers in Neurology. 14: 1069411. PMID 36937522 DOI: 10.3389/fneur.2023.1069411 |
0.713 |
|
| 2023 |
Wang Z, Jin M, Hong W, Liu W, Reczek D, Lagomarsino VN, Hu Y, Weeden T, Frosch MP, Young-Pearse TL, Pradier L, Selkoe D, Walsh DM. Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics. Acta Neuropathologica Communications. 11: 39. PMID 36899414 DOI: 10.1186/s40478-023-01511-2 |
0.3 |
|
| 2022 |
Dickson JR, Frosch MP, Hyman BT. Altered localization of nucleoporin 98 in primary tauopathies. Brain Communications. 5: fcac334. PMID 36601621 DOI: 10.1093/braincomms/fcac334 |
0.444 |
|
| 2022 |
Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Frosch MP, et al. Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England). PMID 36456723 DOI: 10.1007/s12311-022-01501-5 |
0.618 |
|
| 2022 |
Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Frosch MP, et al. Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum (London, England). PMID 36190676 DOI: 10.1007/s12311-022-01471-8 |
0.674 |
|
| 2022 |
Miller MB, Huang AY, Kim J, Zhou Z, Kirkham SL, Maury EA, Ziegenfuss JS, Reed HC, Neil JE, Rento L, Ryu SC, Ma CC, Luquette LJ, Ames HM, Oakley DH, ... Frosch MP, et al. Somatic genomic changes in single Alzheimer's disease neurons. Nature. PMID 35444284 DOI: 10.1038/s41586-022-04640-1 |
0.727 |
|
| 2022 |
Scherlek AA, Kozberg MG, Nicoll JAR, Perosa V, Freeze WM, van der Weerd L, Bacskai BJ, Greenberg SM, Frosch MP, Boche D, van Veluw SJ. Histopathological correlates of haemorrhagic lesions on magnetic resonance imaging in immunized Alzheimer's disease cases. Brain Communications. 4: fcac021. PMID 35224489 DOI: 10.1093/braincomms/fcac021 |
0.306 |
|
| 2022 |
Muñoz-Castro C, Noori A, Magdamo CG, Li Z, Marks JD, Frosch MP, Das S, Hyman BT, Serrano-Pozo A. Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer's disease. Journal of Neuroinflammation. 19: 30. PMID 35109872 DOI: 10.1186/s12974-022-02383-4 |
0.459 |
|
| 2021 |
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Frosch MP, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z |
0.481 |
|
| 2021 |
Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. Journal of Neuropathology and Experimental Neurology. PMID 34498073 DOI: 10.1093/jnen/nlab087 |
0.423 |
|
| 2021 |
Rodriguez S, Sahin A, Schrank BR, Al-Lawati H, Costantino I, Benz E, Fard D, Albers AD, Cao L, Gomez AC, Evans K, Ratti E, Cudkowicz M, Frosch MP, Talkowski M, et al. Genome-encoded cytoplasmic double-stranded RNAs, found in ALS-FTD brain, propagate neuronal loss. Science Translational Medicine. 13. PMID 34233951 DOI: 10.1126/scitranslmed.aaz4699 |
0.365 |
|
| 2021 |
Kamath TV, Klickstein N, Commins C, Fernandes AR, Oakley DH, Frosch MP, Hyman BT, Dujardin S. Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer's cases. Brain Communications. 3: fcab096. PMID 34222869 DOI: 10.1093/braincomms/fcab096 |
0.726 |
|
| 2021 |
Dickson JR, Yoon H, Frosch MP, Hyman BT. Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau. Journal of Neuropathology and Experimental Neurology. PMID 33990839 DOI: 10.1093/jnen/nlab040 |
0.488 |
|
| 2021 |
Oakley DH, Klickstein N, Commins C, Chung M, Dujardin S, Bennett RE, Hyman BT, Frosch MP. Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33893219 DOI: 10.1523/JNEUROSCI.2590-20.2021 |
0.72 |
|
| 2021 |
William CM, Stern MA, Pei X, Saqran L, Ramani M, Frosch MP, Hyman BT. Impairment of visual cortical plasticity by amyloid-beta species. Neurobiology of Disease. 154: 105344. PMID 33766652 DOI: 10.1016/j.nbd.2021.105344 |
0.444 |
|
| 2021 |
Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, ... ... Frosch MP, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022 |
0.367 |
|
| 2021 |
Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, ... ... Frosch MP, et al. Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 33514949 DOI: 10.1038/s41591-021-01251-7 |
0.725 |
|
| 2020 |
Clement NF, DeWitt JC, Frosch MP, Martinez-Lage M, Samore WR, Hedley-Whyte ET. A Simplified Brain Blocking Protocol Optimized for the Diagnosis of Neurodegenerative Disease Saves Time and Money While Preserving Anatomic Relationships. Archives of Pathology & Laboratory Medicine. PMID 33290509 DOI: 10.5858/arpa.2020-0322-OA |
0.496 |
|
| 2020 |
Bryant AG, Hu M, Carlyle BC, Arnold SE, Frosch MP, Das S, Hyman BT, Bennett RE. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in Neurology. 11: 575953. PMID 33041998 DOI: 10.3389/Fneur.2020.575953 |
0.526 |
|
| 2020 |
Asher DM, Belay E, Bigio E, Brandner S, Brubaker SA, Caughey B, Clark B, Damon I, Diamond M, Freund M, Hyman BT, Jucker M, Keene CD, Lieberman AP, Mackiewicz M, ... ... Frosch MP, et al. Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns. Journal of Neuropathology and Experimental Neurology. PMID 33000167 DOI: 10.1093/jnen/nlaa109 |
0.377 |
|
| 2020 |
Charidimou A, Perosa V, Frosch MP, Scherlek AA, Greenberg SM, van Veluw SJ. Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy. Brain : a Journal of Neurology. PMID 32935842 DOI: 10.1093/Brain/Awaa266 |
0.34 |
|
| 2020 |
Mueller C, Berry JD, McKenna-Yasek DM, Gernoux G, Owegi MA, Pothier LM, Douthwright CL, Gelevski D, Luppino SD, Blackwood M, Wightman NS, Oakley DH, Frosch MP, Flotte TR, Cudkowicz ME, et al. Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. The New England Journal of Medicine. 383: 151-158. PMID 32640133 DOI: 10.1056/Nejmoa2005056 |
0.629 |
|
| 2020 |
Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, ... ... Frosch MP, et al. Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 32572268 DOI: 10.1038/S41591-020-0938-9 |
0.761 |
|
| 2020 |
Regenhardt RW, Thon JM, Das AS, Thon OR, Charidimou A, Viswanathan A, Gurol ME, Chwalisz BK, Frosch MP, Cho TA, Greenberg SM. Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation. Jama Neurology. PMID 32568365 DOI: 10.1001/Jamaneurol.2020.1782 |
0.333 |
|
| 2020 |
Oakley DH, Chung M, Klickstein N, Commins C, Hyman BT, Frosch MP. The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue. Journal of Neuropathology and Experimental Neurology. PMID 32388561 DOI: 10.1093/Jnen/Nlaa025 |
0.755 |
|
| 2020 |
Kozberg MG, van Veluw SJ, Frosch MP, Greenberg SM. Hereditary cerebral amyloid angiopathy, Piedmont-type mutation. Neurology. Genetics. 6: e411. PMID 32337337 DOI: 10.1212/Nxg.0000000000000411 |
0.346 |
|
| 2020 |
Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, ... ... Frosch MP, et al. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nature Communications. 11: 667. PMID 32015339 DOI: 10.1038/S41467-019-14279-8 |
0.517 |
|
| 2020 |
van Veluw SJ, Frosch MP, Scherlek AA, Lee D, Greenberg SM, Bacskai BJ. In vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19899377. PMID 31987010 DOI: 10.1177/0271678X19899377 |
0.325 |
|
| 2019 |
Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, et al. PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathologica. PMID 31853635 DOI: 10.1007/S00401-019-02114-9 |
0.396 |
|
| 2019 |
van Veluw SJ, Hou SS, Calvo-Rodriguez M, Arbel-Ornath M, Snyder AC, Frosch MP, Greenberg SM, Bacskai BJ. Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain. Neuron. PMID 31810839 DOI: 10.1016/J.Neuron.2019.10.033 |
0.399 |
|
| 2019 |
Marquié M, Agüero C, Amaral AC, Villarejo-Galende A, Ramanan P, Chong MST, Sáez-Calveras N, Bennett RE, Verwer EE, Kim SJW, Dhaynaut M, Alvarez VE, Johnson KA, McKee AC, Frosch MP, et al. [F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series. Acta Neuropathologica Communications. 7: 164. PMID 31661038 DOI: 10.1186/S40478-019-0808-1 |
0.367 |
|
| 2019 |
Charidimou A, Frosch MP, Salman RA, Baron JC, Cordonnier C, Hernandez-Guillamon M, Linn J, Raposo N, Rodrigues M, Romero JR, Schneider JA, Schreiber S, Smith EE, van Buchem MA, Viswanathan A, et al. Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. International Journal of Stroke : Official Journal of the International Stroke Society. 1747493019855888. PMID 31514686 DOI: 10.1177/1747493019855888 |
0.356 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Frosch MP, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7 |
0.415 |
|
| 2019 |
Hwang J, Bank AM, Mortazavi F, Oakley DH, Frosch MP, Schmahmann JD. Spinal cord α-synuclein deposition associated with myoclonus in patients with MSA-C. Neurology. 93: 302-309. PMID 31405935 DOI: 10.1212/Wnl.0000000000007949 |
0.644 |
|
| 2019 |
Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth A. A vicious cycle of β amyloid-dependent neuronal hyperactivation. Science (New York, N.Y.). 365: 559-565. PMID 31395777 DOI: 10.1126/Science.Aay0198 |
0.393 |
|
| 2019 |
Wong B, Lucente DE, MacLean J, Padmanabhan J, Quimby M, Brandt KD, Putcha D, Sherman J, Frosch MP, McGinnis S, Dickerson BC. Diagnostic evaluation and monitoring of patients with posterior cortical atrophy. Neurodegenerative Disease Management. PMID 31392920 DOI: 10.2217/Nmt-2018-0052 |
0.335 |
|
| 2019 |
Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Frosch MP, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/J.Cell.2019.06.024 |
0.446 |
|
| 2019 |
Gomez-Isla T, Frosch MP. The Challenge of Defining Alzheimer Disease Based on Biomarkers in the Absence of Symptoms. Jama Neurology. PMID 31305888 DOI: 10.1001/Jamaneurol.2019.1667 |
0.335 |
|
| 2019 |
Shirvan J, Clement N, Ye R, Katz S, Schultz A, Johnson KA, Gomez-Isla T, Frosch M, Growdon JH, Gomperts SN. Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. Neurology. PMID 31243072 DOI: 10.1212/Wnl.0000000000007855 |
0.315 |
|
| 2019 |
Pasi M, Pongpitakmetha T, Charidimou A, Singh SD, Tsai HH, Xiong L, Boulouis G, Warren AD, Rosand J, Frosch MP, Viswanathan A, Gurol ME, Greenberg SM. Cerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy. Stroke. STROKEAHA119024843. PMID 31159702 DOI: 10.1161/Strokeaha.119.024843 |
0.332 |
|
| 2019 |
van Veluw SJ, Scherlek AA, Freeze WM, Ter Telgte A, van der Kouwe AJ, Bacskai BJ, Frosch MP, Greenberg SM. Different microvascular alterations underlie microbleeds and microinfarcts. Annals of Neurology. PMID 31152566 DOI: 10.1002/Ana.25512 |
0.35 |
|
| 2019 |
Brinkmalm G, Hong W, Wang Z, Liu W, O'Malley TT, Sun X, Frosch MP, Selkoe DJ, Portelius E, Zetterberg H, Blennow K, Walsh DM. Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain. Brain : a Journal of Neurology. 142: 1441-1457. PMID 31032851 DOI: 10.1093/Brain/Awz066 |
0.399 |
|
| 2019 |
Aguero C, Dhaynaut M, Normandin MD, Amaral AC, Guehl NJ, Neelamegam R, Marquie M, Johnson KA, El Fakhri G, Frosch MP, Gomez-Isla T. Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue. Acta Neuropathologica Communications. 7: 37. PMID 30857558 DOI: 10.1186/S40478-019-0686-6 |
0.35 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Frosch MP, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
0.416 |
|
| 2019 |
van Veluw SJ, Reijmer YD, van der Kouwe AJ, Charidimou A, Riley GA, Leemans A, Bacskai BJ, Frosch MP, Viswanathan A, Greenberg SM. Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy. Neurology. PMID 30700595 DOI: 10.1212/Wnl.0000000000007005 |
0.307 |
|
| 2019 |
Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy. Stroke. STROKEAHA118023788. PMID 30661497 DOI: 10.1161/Strokeaha.118.023788 |
0.36 |
|
| 2019 |
Pasi M, Charidimou A, Boulouis G, Fotiadis P, Morotti A, Xiong L, Marini S, Ayres A, Frosch MP, Goldstein JN, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Cerebral small vessel disease in patients with spontaneous cerebellar hemorrhage. Journal of Neurology. PMID 30617995 DOI: 10.1007/S00415-018-09177-W |
0.328 |
|
| 2019 |
Thon JM, Regenhardt RW, Thon OR, Charidimou A, Viswanathan A, Gurol ME, Chwalisz BK, Frosch M, Cho TA, Greenberg SM. Abstract WP426: Cerebral Amyloid Angiopathy-related Inflammation: Immunosuppressive Treatment and Outcome Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wp426 |
0.328 |
|
| 2018 |
Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris D, Walsh DM. PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity. Brain Research. PMID 30593771 DOI: 10.1016/J.Brainres.2018.12.038 |
0.301 |
|
| 2018 |
Dujardin S, Bégard S, Caillierez R, Lachaud C, Carrier S, Lieger S, Gonzalez JA, Deramecourt V, Déglon N, Maurage CA, Frosch MP, Hyman BT, Colin M, Buée L. Different tau species lead to heterogeneous tau pathology propagation and misfolding. Acta Neuropathologica Communications. 6: 132. PMID 30497516 DOI: 10.1186/S40478-018-0637-7 |
0.537 |
|
| 2018 |
Bale TA, Jordan JT, Rapalino O, Ramamurthy N, Jessop N, DeWitt JC, Nardi V, Martinez-Lage Alvarez M, Frosch M, Batchelor TT, Louis DN, Iafrate AJ, Cahill DP, Lennerz JK. Financially Effective Test-Algorithm to Identify an Aggressive, EGFR-amplified Variant of IDH-Wildtype, Lower-Grade Diffuse Glioma. Neuro-Oncology. PMID 30496526 DOI: 10.1093/Neuonc/Noy201 |
0.436 |
|
| 2018 |
Frosch MP. "When sex influences the brain: implications for Alzheimer disease". Acta Neuropathologica. PMID 30443762 DOI: 10.1007/S00401-018-1931-Y |
0.378 |
|
| 2018 |
Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Tick-Chong MS, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, ... ... Frosch MP, et al. Distinct cytokine profiles in human brains resilient to Alzheimer's pathology. Neurobiology of Disease. PMID 30336198 DOI: 10.1016/J.Nbd.2018.10.009 |
0.411 |
|
| 2018 |
Ly KI, Oakley DH, Pine AB, Frosch MP, Chiou SH, Betensky RA, Pomerantz SR, Hochberg FH, Batchelor TT, Cahill DP, Dietrich J. Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study. The Oncologist. PMID 30097523 DOI: 10.1634/Theoncologist.2018-0086 |
0.66 |
|
| 2018 |
Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DM. An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer's disease. Nature Communications. 9: 2676. PMID 29992960 DOI: 10.1038/S41467-018-05068-W |
0.417 |
|
| 2018 |
DeVos SL, Corjuc BT, Oakley DH, Nobuhara CK, Bannon RN, Chase A, Commins C, Gonzalez JA, Dooley PM, Frosch MP, Hyman BT. Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain. Frontiers in Neuroscience. 12: 267. PMID 29740275 DOI: 10.3389/Fnins.2018.00267 |
0.758 |
|
| 2018 |
DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, et al. Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo. Brain : a Journal of Neurology. PMID 29733334 DOI: 10.1093/Brain/Awy117 |
0.532 |
|
| 2018 |
Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DM. Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer's disease brain. Acta Neuropathologica. PMID 29687257 DOI: 10.1007/S00401-018-1846-7 |
0.414 |
|
| 2018 |
Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, ... ... Frosch MP, et al. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335. PMID 29674595 DOI: 10.1126/Science.Aao4750 |
0.461 |
|
| 2017 |
Colom-Cadena M, Pegueroles J, Herrmann AG, Henstridge CM, Muñoz L, Querol-Vilaseca M, Martín-Paniello CS, Luque-Cabecerans J, Clarimon J, Belbin O, Núñez-Llaves R, Blesa R, Smith C, McKenzie CA, Frosch MP, et al. Synaptic phosphorylated α-synuclein in dementia with Lewy bodies. Brain : a Journal of Neurology. 140: 3204-3214. PMID 29177427 DOI: 10.1093/Brain/Awx275 |
0.466 |
|
| 2017 |
Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse T, Spires-Jones TL, Walsh DM. Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29101243 DOI: 10.1523/Jneurosci.2009-17.2017 |
0.393 |
|
| 2017 |
Marquié M, Verwer EE, Meltzer AC, Kim SJW, Agüero C, Gonzalez J, Makaretz SJ, Siao Tick Chong M, Ramanan P, Amaral AC, Normandin MD, Vanderburg CR, Gomperts SN, Johnson KA, Frosch MP, et al. Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case. Acta Neuropathologica Communications. 5: 75. PMID 29047416 DOI: 10.1186/S40478-017-0482-0 |
0.339 |
|
| 2017 |
DeWitt JC, Jordan JT, Frosch MP, Samore WR, Iafrate AJ, Louis DN, Lennerz JK. Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations. Neuro-Oncology. PMID 29016871 DOI: 10.1093/Neuonc/Nox120 |
0.463 |
|
| 2017 |
William CM, Saqran L, Stern MA, Chiang CL, Herrick S, Rangwala A, Albers MW, Frosch MP, Hyman BT. Activity-dependent dysfunction in visual and olfactory sensory systems in mouse models of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28899917 DOI: 10.1523/Jneurosci.1045-17.2017 |
0.429 |
|
| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Frosch MP, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.471 |
|
| 2017 |
Marquié M, Siao Tick Chong M, Antón-Fernández A, Verwer EE, Sáez-Calveras N, Meltzer AC, Ramanan P, Amaral AC, Gonzalez J, Normandin MD, Frosch MP, Gómez-Isla T. [F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging. Acta Neuropathologica. PMID 28612291 DOI: 10.1007/S00401-017-1740-8 |
0.386 |
|
| 2017 |
Bennett RE, DeVos SL, Dujardin S, Corjuc B, Gor R, Gonzalez J, Roe AD, Frosch MP, Pitstick R, Carlson GA, Hyman BT. Enhanced Tau Aggregation in the Presence of Amyloid β. The American Journal of Pathology. PMID 28500862 DOI: 10.1016/J.Ajpath.2017.03.011 |
0.535 |
|
| 2017 |
Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, et al. Tau Antibody-Targeting Pathological Species Block Neuronal Uptake and Interneuron Propagation of Tau in Vitro. The American Journal of Pathology. PMID 28408124 DOI: 10.1016/J.Ajpath.2017.01.022 |
0.516 |
|
| 2017 |
Williams EA, McGuone D, Frosch MP, Hyman BT, Laver N, Stemmer-Rachamimov A. Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 28379416 DOI: 10.1093/Jnen/Nlx020 |
0.553 |
|
| 2017 |
Frosch MP. Tau aggregates: Where, When, Why and What consequences? Neuropathology and Applied Neurobiology. PMID 28370398 DOI: 10.1111/Nan.12400 |
0.409 |
|
| 2017 |
Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, ... ... Frosch MP, et al. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science (New York, N.Y.). 355. PMID 28360267 DOI: 10.1126/Science.Aai8478 |
0.447 |
|
| 2017 |
Charidimou A, Boulouis G, Gurol ME, Ayata C, Bacskai BJ, Frosch MP, Viswanathan A, Greenberg SM. Emerging concepts in sporadic cerebral amyloid angiopathy. Brain : a Journal of Neurology. PMID 28334869 DOI: 10.1093/Brain/Awx047 |
0.401 |
|
| 2017 |
Veluw SJv, Kouwe AJvd, Reijmer YD, Charidimou A, Viswanathan A, Frosch MP, Greenberg SM. Mri-Histopathology Associations Of Microbleeds And Microinfarcts In Intact Ex Vivo Hemispheres Of Patients With Cerebral Amyloid Angiopathy Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.716 |
0.345 |
|
| 2016 |
Marquié M, Normandin MD, Meltzer AC, Siao Tick Chong M, Andrea NV, Antón-Fernández A, Klunk WE, Mathis CA, Ikonomovic MD, Debnath M, Bien EA, Vanderburg CR, Costantino I, Makaretz S, DeVos SL, ... ... Frosch MP, et al. Pathologic correlations of [F-18]-AV-1451 imaging in non-Alzheimer tauopathies. Annals of Neurology. PMID 27997036 DOI: 10.1002/Ana.24844 |
0.737 |
|
| 2016 |
Troncone L, Luciani M, Coggins M, Wilker EH, Ho CY, Codispoti KE, Frosch MP, Kayed R, Del Monte F. Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease: Mind the Heart. Journal of the American College of Cardiology. 68: 2395-2407. PMID 27908343 DOI: 10.1016/J.Jacc.2016.08.073 |
0.378 |
|
| 2016 |
Sellal F, Wallon D, Martinez-Almoyna L, Marelli C, Dhar A, Oesterlé H, Rovelet-Lecrux A, Rousseau S, Kourkoulis CE, Rosand J, DiPucchio ZY, Frosch M, Gombert C, Audoin B, Mine M, et al. APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. Journal of Alzheimer's Disease : Jad. PMID 27858710 DOI: 10.3233/Jad-160709 |
0.394 |
|
| 2016 |
Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, ... ... Frosch MP, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. PMID 27806376 DOI: 10.1038/Nature20123 |
0.457 |
|
| 2016 |
van Veluw SJ, Kuijf HJ, Charidimou A, Viswanathan A, Biessels GJ, Rozemuller AJ, Frosch MP, Greenberg SM. Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy. Acta Neuropathologica. PMID 27771772 DOI: 10.1007/S00401-016-1635-0 |
0.367 |
|
| 2016 |
Liu J, Costantino I, Venugopalan N, Fischetti RF, Hyman BT, Frosch MP, Gomez-Isla T, Makowski L. Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue. Scientific Reports. 6: 33079. PMID 27629394 DOI: 10.1038/Srep33079 |
0.521 |
|
| 2016 |
Lauer A, van Veluw SJ, William CM, Charidimou A, Roongpiboonsopit D, Vashkevich A, Ayres A, Martinez-Ramirez S, Gurol EM, Biessels GJ, Frosch M, Greenberg SM, Viswanathan A. Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy. Neurology. PMID 27613583 DOI: 10.1212/Wnl.0000000000003184 |
0.35 |
|
| 2016 |
Chang J, Arani K, Chew S, Frosch MP, Gonzalez RG, Maza N, Romero JM. Susceptibility Etching on MRI in Patients with Microangiopathy. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 27539492 DOI: 10.1111/Jon.12384 |
0.307 |
|
| 2016 |
Charidimou A, Martinez-Ramirez S, Reijmer YD, Oliveira-Filho J, Lauer A, Roongpiboonsopit D, Frosch M, Vashkevich A, Ayres A, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Total Magnetic Resonance Imaging Burden of Small Vessel Disease in Cerebral Amyloid Angiopathy: An Imaging-Pathologic Study of Concept Validation. Jama Neurology. PMID 27366898 DOI: 10.1001/Jamaneurol.2016.0832 |
0.345 |
|
| 2016 |
Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, ... ... Frosch MP, et al. Seed-competent HMW tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients. Annals of Neurology. PMID 27351289 DOI: 10.1002/Ana.24716 |
0.554 |
|
| 2016 |
Rudinskiy N, Fuerer C, Demurtas D, Zamorano S, De Piano C, Herrmann A, Spires-Jones TL, Oeckl P, Otto M, Frosch MP, Moniatte M, Hyman BT, Schmid AW. Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27130892 DOI: 10.1016/J.Jalz.2016.03.011 |
0.52 |
|
| 2016 |
Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT. Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum. Journal of Neuropathology and Experimental Neurology. PMID 27105663 DOI: 10.1093/Jnen/Nlw026 |
0.488 |
|
| 2016 |
Walker MA, Mohler KP, Hopkins KW, Oakley DH, Sweetser DA, Ibba M, Frosch MP, Thibert RL. Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease. Journal of Child Neurology. PMID 27095821 DOI: 10.1177/0883073816643402 |
0.679 |
|
| 2016 |
Jin M, O'Malley TT, Boyd J, Liu W, Frosch MP, Walsh DM, Selkoe DJ. P4-058: A Novel Paradigm for the Identification and Targeting of Bioactive Abeta Species from Alzheimer Brain Alzheimer's & Dementia. 12: P1037-P1037. DOI: 10.1016/J.Jalz.2016.06.2148 |
0.34 |
|
| 2015 |
Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, Boulouis G, Piazza F, DiFrancesco JC, Frosch MP, Pontes-Neto OV, Shoamanesh A, Reijmer Y, Vashkevich A, Ayres AM, et al. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. Jama Neurology. 1-6. PMID 26720093 DOI: 10.1001/Jamaneurol.2015.4078 |
0.372 |
|
| 2015 |
Serrano-Pozo A, Betensky RA, Frosch MP, Hyman BT. Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease. The American Journal of Pathology. PMID 26687817 DOI: 10.1016/J.Ajpath.2015.10.010 |
0.525 |
|
| 2015 |
Wood LB, Winslow AR, Proctor EA, McGuone D, Mordes DA, Frosch MP, Hyman BT, Lauffenburger DA, Haigis KM. Identification of neurotoxic cytokines by profiling Alzheimer's disease tissues and neuron culture viability screening. Scientific Reports. 5: 16622. PMID 26564777 DOI: 10.1038/Srep16622 |
0.524 |
|
| 2015 |
Takeda S, Wegmann S, Cho H, DeVos SL, Commins C, Roe AD, Nicholls SB, Carlson GA, Pitstick R, Nobuhara CK, Costantino I, Frosch MP, Müller DJ, Irimia D, Hyman BT. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain. Nature Communications. 6: 8490. PMID 26458742 DOI: 10.1038/Ncomms9490 |
0.543 |
|
| 2015 |
Musolino PL, Gong Y, Snyder JM, Jimenez S, Lok J, Lo EH, Moser AB, Grabowski EF, Frosch MP, Eichler FS. Brain endothelial dysfunction in cerebral adrenoleukodystrophy. Brain : a Journal of Neurology. PMID 26377633 DOI: 10.1093/Brain/Awv250 |
0.302 |
|
| 2015 |
Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, ... Frosch MP, et al. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Annals of Neurology. PMID 26344059 DOI: 10.1002/Ana.24517 |
0.46 |
|
| 2015 |
Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492 |
0.508 |
|
| 2015 |
Zhao L, Arbel-Ornath M, Wang X, Betensky RA, Greenberg SM, Frosch MP, Bacskai BJ. Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy. Neurobiology of Aging. PMID 26248866 DOI: 10.1016/J.Neurobiolaging.2015.07.016 |
0.315 |
|
| 2015 |
Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM, Frosch MP, Walsh DM. The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25846299 DOI: 10.1016/J.Jalz.2015.01.005 |
0.393 |
|
| 2015 |
Charidimou A, Martinez-Ramirez S, Shoamanesh A, Oliveira-Filho J, Frosch M, Vashkevich A, Ayres A, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Cerebral amyloid angiopathy with and without hemorrhage: evidence for different disease phenotypes. Neurology. 84: 1206-12. PMID 25716356 DOI: 10.1212/Wnl.0000000000001398 |
0.404 |
|
| 2015 |
Etherton MR, Neagu MR, Oakley DH, Koch MJ, Shin JH, Frosch MP, Berkowitz AL, Dietrich J. A 20-year-old man with back pain and lower extremity weakness. Jama Neurology. 72: 363-6. PMID 25621865 DOI: 10.1001/Jamaneurol.2014.3833 |
0.655 |
|
| 2015 |
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Frosch MP, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157 |
0.519 |
|
| 2015 |
Takeda S, Commins C, Wegmann S, Roe AD, Fan Z, DeVos SL, Costantino I, Trisini Lipsanopoulos A, Frosch MP, Hyman BT. P3-071: A unique high-molecular-weight tau species is involved in propagation and accumulates in the cerebrospinal fluid of Alzheimer's disease patients Alzheimer's & Dementia. 11: P644-P644. DOI: 10.1016/J.Jalz.2015.06.938 |
0.498 |
|
| 2014 |
Tai HC, Wang BY, Serrano-Pozo A, Frosch MP, Spires-Jones TL, Hyman BT. Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease. Acta Neuropathologica Communications. 2: 146. PMID 25330988 DOI: 10.1186/S40478-014-0146-2 |
0.524 |
|
| 2014 |
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Frosch MP, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491 |
0.465 |
|
| 2014 |
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, ... ... Frosch MP, et al. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Plos Genetics. 10: e1004606. PMID 25188341 DOI: 10.1371/Journal.Pgen.1004606 |
0.535 |
|
| 2014 |
Lanthier S, Calabrese LH, Ferro JM, Putaala J, Strbian D, Chagnon M, Frosch MP, Singhal AB, Salvarani C, Létourneau-Guillon L, Poppe AY, Guilbert F, Raymond J, Muccilli A. The INTERnational Study on Primary Angiitis of the CEntral nervous system--a call to the world. International Journal of Stroke : Official Journal of the International Stroke Society. 9: E23. PMID 24909198 DOI: 10.1111/Ijs.12284 |
0.301 |
|
| 2014 |
Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. Journal of Neuropathology and Experimental Neurology. 73: 467-73. PMID 24709683 DOI: 10.1097/Nen.0000000000000070 |
0.468 |
|
| 2014 |
Landau SM, Frosch MP. Tracking the earliest pathologic changes in Alzheimer disease. Neurology. 82: 1576-7. PMID 24706009 DOI: 10.1212/Wnl.0000000000000392 |
0.416 |
|
| 2014 |
Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125 |
0.522 |
|
| 2014 |
Annese J, Schenker-Ahmed NM, Bartsch H, Maechler P, Sheh C, Thomas N, Kayano J, Ghatan A, Bresler N, Frosch MP, Klaming R, Corkin S. Postmortem examination of patient H.M.'s brain based on histological sectioning and digital 3D reconstruction. Nature Communications. 5: 3122. PMID 24473151 DOI: 10.1038/Ncomms4122 |
0.31 |
|
| 2014 |
Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... Frosch MP, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X |
0.303 |
|
| 2013 |
Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BT. Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. Journal of Neuropathology and Experimental Neurology. 72: 1182-92. PMID 24226270 DOI: 10.1097/Nen.0000000000000016 |
0.534 |
|
| 2013 |
Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, et al. Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology. Brain : a Journal of Neurology. 136: 2510-26. PMID 23824488 DOI: 10.1093/Brain/Awt171 |
0.512 |
|
| 2013 |
Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJ. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathologica. 126: 353-64. PMID 23818064 DOI: 10.1007/S00401-013-1145-2 |
0.41 |
|
| 2013 |
Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Studying synapses in human brain with array tomography and electron microscopy. Nature Protocols. 8: 1366-80. PMID 23787894 DOI: 10.1038/Nprot.2013.078 |
0.452 |
|
| 2013 |
Serrano-Pozo A, Muzikansky A, Gómez-Isla T, Growdon JH, Betensky RA, Frosch MP, Hyman BT. Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 462-71. PMID 23656989 DOI: 10.1097/Nen.0B013E3182933788 |
0.52 |
|
| 2013 |
Serrano-Pozo A, Gómez-Isla T, Growdon JH, Frosch MP, Hyman BT. A phenotypic change but not proliferation underlies glial responses in Alzheimer disease. The American Journal of Pathology. 182: 2332-44. PMID 23602650 DOI: 10.1016/J.Ajpath.2013.02.031 |
0.528 |
|
| 2013 |
McFarland NR, Burdett T, Desjardins CA, Frosch MP, Schwarzschild MA. Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders. Neuro-Degenerative Diseases. 12: 189-98. PMID 23467193 DOI: 10.1159/000346370 |
0.367 |
|
| 2013 |
Augustinack JC, Huber KE, Stevens AA, Roy M, Frosch MP, van der Kouwe AJ, Wald LL, Van Leemput K, McKee AC, Fischl B. Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI. Neuroimage. 64: 32-42. PMID 22960087 DOI: 10.1016/J.Neuroimage.2012.08.071 |
0.317 |
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| 2013 |
Horton LC, Frosch MP, Vangel MG, Weigel-DiFranco C, Berson EL, Schmahmann JD. Spinocerebellar ataxia type 7: clinical course, phenotype-genotype correlations, and neuropathology. Cerebellum (London, England). 12: 176-93. PMID 22915085 DOI: 10.1007/S12311-012-0412-4 |
0.312 |
|
| 2012 |
Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15181-92. PMID 23100439 DOI: 10.1523/Jneurosci.1542-12.2012 |
0.534 |
|
| 2012 |
Gregory JL, Prada CM, Fine SJ, Garcia-Alloza M, Betensky RA, Arbel-Ornath M, Greenberg SM, Bacskai BJ, Frosch MP. Reducing available soluble β-amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice. Journal of Neuropathology and Experimental Neurology. 71: 1009-17. PMID 23095848 DOI: 10.1097/Nen.0B013E3182729845 |
0.405 |
|
| 2012 |
Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed Whole Slide Image viewing system. Studies in Health Technology and Informatics. 179: 239-49. PMID 22925804 DOI: 10.3233/978-1-61499-086-4-239 |
0.368 |
|
| 2012 |
Tai HC, Serrano-Pozo A, Hashimoto T, Frosch MP, Spires-Jones TL, Hyman BT. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. The American Journal of Pathology. 181: 1426-35. PMID 22867711 DOI: 10.1016/J.Ajpath.2012.06.033 |
0.526 |
|
| 2012 |
Serrano-Pozo A, Mielke ML, Muzitansky A, Gómez-Isla T, Growdon JH, Bacskai BJ, Betensky RA, Frosch MP, Hyman BT. Stable size distribution of amyloid plaques over the course of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 694-701. PMID 22805771 DOI: 10.1097/Nen.0B013E31825E77De |
0.524 |
|
| 2012 |
Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Frosch M, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801 |
0.381 |
|
| 2012 |
William CM, Andermann ML, Goldey GJ, Roumis DK, Reid RC, Shatz CJ, Albers MW, Frosch MP, Hyman BT. Synaptic plasticity defect following visual deprivation in Alzheimer's disease model transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8004-11. PMID 22674275 DOI: 10.1523/JNEUROSCI.5369-11.2012 |
0.414 |
|
| 2012 |
Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain : a Journal of Neurology. 135: 2155-68. PMID 22637583 DOI: 10.1093/Brain/Aws127 |
0.524 |
|
| 2012 |
Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Frosch MP, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161 |
0.403 |
|
| 2012 |
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7 |
0.52 |
|
| 2012 |
Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/J.Jalz.2011.10.007 |
0.556 |
|
| 2012 |
Augustinack JC, Huber KE, Postelnicu GM, Kakunoori S, Wang R, van der Kouwe AJ, Wald LL, Stein TD, Frosch MP, Fischl B. Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathologica. 123: 85-96. PMID 22160360 DOI: 10.1007/S00401-011-0929-5 |
0.379 |
|
| 2012 |
Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/S00401-011-0910-3 |
0.547 |
|
| 2012 |
Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Analytical Cellular Pathology (Amsterdam). 35: 65-73. PMID 22063731 DOI: 10.3233/Acp-2011-0042 |
0.442 |
|
| 2011 |
Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT. Neuropathological alterations in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 1: a006189. PMID 22229116 DOI: 10.1101/Cshperspect.A006189 |
0.555 |
|
| 2011 |
Garcia-Alloza M, Gregory J, Kuchibhotla KV, Fine S, Wei Y, Ayata C, Frosch MP, Greenberg SM, Bacskai BJ. Cerebrovascular lesions induce transient β-amyloid deposition. Brain : a Journal of Neurology. 134: 3697-707. PMID 22120142 DOI: 10.1093/Brain/Awr300 |
0.392 |
|
| 2011 |
Kopeikina KJ, Carlson GA, Pitstick R, Ludvigson AE, Peters A, Luebke JI, Koffie RM, Frosch MP, Hyman BT, Spires-Jones TL. Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. The American Journal of Pathology. 179: 2071-82. PMID 21854751 DOI: 10.1016/J.Ajpath.2011.07.004 |
0.529 |
|
| 2011 |
Sperling RA, Jack CR, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 367-85. PMID 21784348 DOI: 10.1016/J.Jalz.2011.05.2351 |
0.524 |
|
| 2011 |
Serrano-Pozo A, Mielke ML, Gómez-Isla T, Betensky RA, Growdon JH, Frosch MP, Hyman BT. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. The American Journal of Pathology. 179: 1373-84. PMID 21777559 DOI: 10.1016/J.Ajpath.2011.05.047 |
0.551 |
|
| 2011 |
Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, RodrÃguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, et al. Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proceedings of the National Academy of Sciences of the United States of America. 108: E128-35. PMID 21555590 DOI: 10.1073/Pnas.1101964108 |
0.327 |
|
| 2011 |
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Frosch MP, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801 |
0.405 |
|
| 2011 |
Greenberg SM, Frosch MP. Life imitates art: anti-amyloid antibodies and inflammatory cerebral amyloid angiopathy. Neurology. 76: 772-3. PMID 21357829 DOI: 10.1212/Wnl.0B013E31820E7Bce |
0.371 |
|
| 2011 |
di Tomaso E, Snuderl M, Kamoun WS, Duda DG, Auluck PK, Fazlollahi L, Andronesi OC, Frosch MP, Wen PY, Plotkin SR, Hedley-Whyte ET, Sorensen AG, Batchelor TT, Jain RK. Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Research. 71: 19-28. PMID 21199795 DOI: 10.1158/0008-5472.Can-10-2602 |
0.722 |
|
| 2011 |
Skoglund L, Matsui T, Freeman SH, Wallin A, Blom ES, Frosch MP, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. Novel progranulin mutation detected in 2 patients with FTLD. Alzheimer Disease and Associated Disorders. 25: 173-8. PMID 20975516 DOI: 10.1097/Wad.0B013E3181Fbc22C |
0.423 |
|
| 2011 |
Rutgers KS, van Remoortere A, van Buchem MA, Verrips CT, Greenberg SM, Bacskai BJ, Frosch MP, van Duinen SG, Maat-Schieman ML, van der Maarel SM. Differential recognition of vascular and parenchymal beta amyloid deposition. Neurobiology of Aging. 32: 1774-83. PMID 20015576 DOI: 10.1016/J.Neurobiolaging.2009.11.012 |
0.305 |
|
| 2011 |
Holtzman D, Hyman B, Lee V, Spires-Jones T, Koffie R, Hashimoto T, Joyner D, Hou S, Kopeikina K, Frosch M. O1-05-01: APOE4 plays a role in Abeta-mediated synapse loss in Alzheimer's disease Alzheimer's & Dementia. 7: S103-S104. DOI: 10.1016/J.Jalz.2011.05.256 |
0.484 |
|
| 2010 |
Biffi A, Plourde A, Shen Y, Onofrio R, Smith EE, Frosch M, Prada CM, Gusella J, Greenberg SM, Rosand J. Screening for familial APP mutations in sporadic cerebral amyloid angiopathy. Plos One. 5: e13949. PMID 21085603 DOI: 10.1371/Journal.Pone.0013949 |
0.343 |
|
| 2010 |
Dierksen GA, Skehan ME, Khan MA, Jeng J, Nandigam RN, Becker JA, Kumar A, Neal KL, Betensky RA, Frosch MP, Rosand J, Johnson KA, Viswanathan A, Salat DH, Greenberg SM. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Annals of Neurology. 68: 545-8. PMID 20865701 DOI: 10.1002/Ana.22099 |
0.359 |
|
| 2010 |
Lu Q, Ding K, Frosch MP, Jones S, Wolfe M, Xia W, Lanford GW. Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution. Journal of Alzheimer's Disease : Jad. 22: 235-45. PMID 20847418 DOI: 10.3233/Jad-2010-100585 |
0.349 |
|
| 2010 |
Smith EE, Nandigam KR, Chen YW, Jeng J, Salat D, Halpin A, Frosch M, Wendell L, Fazen L, Rosand J, Viswanathan A, Greenberg SM. MRI markers of small vessel disease in lobar and deep hemispheric intracerebral hemorrhage. Stroke; a Journal of Cerebral Circulation. 41: 1933-8. PMID 20689084 DOI: 10.1161/Strokeaha.110.579078 |
0.326 |
|
| 2010 |
Huttunen HJ, Havas D, Peach C, Barren C, Duller S, Xia W, Frosch MP, Hutter-Paier B, Windisch M, Kovacs DM. The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice. Journal of Neuropathology and Experimental Neurology. 69: 777-88. PMID 20613640 DOI: 10.1097/Nen.0B013E3181E77Ed9 |
0.374 |
|
| 2010 |
Nelson PT, Kukull WA, Frosch MP. Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations. Journal of Neuropathology and Experimental Neurology. 69: 449-54. PMID 20418781 DOI: 10.1097/Nen.0B013E3181D8Db07 |
0.422 |
|
| 2010 |
Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a Journal of Neurology. 133: 1312-27. PMID 20360050 DOI: 10.1093/Brain/Awq056 |
0.513 |
|
| 2010 |
Crittenden JR, Dunn DE, Merali FI, Woodman B, Yim M, Borkowska AE, Frosch MP, Bates GP, Housman DE, Lo DC, Graybiel AM. CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. Human Molecular Genetics. 19: 1756-65. PMID 20147317 DOI: 10.1093/Hmg/Ddq055 |
0.355 |
|
| 2009 |
Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, et al. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Archives of Pathology & Laboratory Medicine. 133: 1949-53. PMID 19961250 DOI: 10.1043/1543-2165-133.12.1949 |
0.465 |
|
| 2009 |
Skoglund L, Ingvast S, Matsui T, Freeman SH, Frosch MP, Brundin R, Giedraitis V, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration. Dementia and Geriatric Cognitive Disorders. 28: 471-5. PMID 19940479 DOI: 10.1159/000260046 |
0.481 |
|
| 2009 |
Fischl B, Stevens AA, Rajendran N, Yeo BT, Greve DN, Van Leemput K, Polimeni JR, Kakunoori S, Buckner RL, Pacheco J, Salat DH, Melcher J, Frosch MP, Hyman BT, Grant PE, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 47: 8-17. PMID 19376238 DOI: 10.1016/J.Neuroimage.2009.04.033 |
0.493 |
|
| 2009 |
Freeman SH, Hyman BT, Sims KB, Hedley-Whyte ET, Vossough A, Frosch MP, Schmahmann JD. Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observations. Brain Pathology (Zurich, Switzerland). 19: 39-47. PMID 18422757 DOI: 10.1111/J.1750-3639.2008.00163.X |
0.61 |
|
| 2008 |
Greenberg SM, Grabowski T, Gurol ME, Skehan ME, Nandigam RN, Becker JA, Garcia-Alloza M, Prada C, Frosch MP, Rosand J, Viswanathan A, Smith EE, Johnson KA. Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B. Annals of Neurology. 64: 587-91. PMID 19067370 DOI: 10.1002/Ana.21528 |
0.36 |
|
| 2008 |
Freeman SH, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Locascio JJ, Lipsitz LA, Hyman BT. Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 67: 1205-12. PMID 19018241 DOI: 10.1097/Nen.0B013E31818Fc72F |
0.636 |
|
| 2008 |
Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP. TAR-DNA binding protein 43 in Pick disease. Journal of Neuropathology and Experimental Neurology. 67: 62-7. PMID 18091558 DOI: 10.1097/Nen.0B013E3181609361 |
0.506 |
|
| 2008 |
di Tomaso E, Frosch MP, Auluck PK, Cahill D, Duda DG, Plotkin SR, Loeffler JS, Sorensen AG, Batchelor TT, Jain RK. Characterization of blood vessels in brain autopsies of GBM patients who received antiangiogenic treatment Journal of Clinical Oncology. 26: 2009-2009. DOI: 10.1200/Jco.2008.26.15_Suppl.2009 |
0.664 |
|
| 2008 |
Johnson K, Grabowski T, Gurol M, Skehan M, Nandigam R, Becker J, Garcia-Alloza M, Prada C, Frosch M, Rosand J, Smith E, Greenberg S. P1-254: Early detection of hereditary cerebral amyloid angiopathy with Pittsburgh Compound B Alzheimer's & Dementia. 4: T290-T290. DOI: 10.1016/J.Jalz.2008.05.844 |
0.356 |
|
| 2008 |
Freeman S, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Lipsitz L, Hyman BT. P4-154: Neuronal atrophy and neuropil loss, rather than neuronal loss, underlies age-related cortical brain atrophy in elderly subjects without Alzheimer's disease Alzheimer's & Dementia. 4: T715-T715. DOI: 10.1016/J.Jalz.2008.05.2221 |
0.488 |
|
| 2008 |
Prada CM, Garcia-Alloza M, Fine S, Betensky RA, Ebiana V, Greenber SM, Bacskai BJ, Frosch MP. P2-353: Reducing the availability of soluble Aβ halts progression of cerebral amyloid angiopathy in transgenic mice Alzheimer's & Dementia. 4: T476-T476. DOI: 10.1016/J.Jalz.2008.05.1431 |
0.35 |
|
| 2008 |
Kowa H, Matsui T, Bouzou B, Clark T, Freeman S, Frosch M, Hyman B. P2-194: Complement pathways are upregulated in angular gyrus of primary progressive aphasia cases Alzheimer's & Dementia. 4: T427-T428. DOI: 10.1016/J.Jalz.2008.05.1268 |
0.406 |
|
| 2007 |
Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT. Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains. Acta Neuropathologica. 114: 471-9. PMID 17721707 DOI: 10.1007/S00401-007-0280-Z |
0.513 |
|
| 2007 |
Shin HK, Jones PB, Garcia-Alloza M, Borrelli L, Greenberg SM, Bacskai BJ, Frosch MP, Hyman BT, Moskowitz MA, Ayata C. Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain : a Journal of Neurology. 130: 2310-9. PMID 17638859 DOI: 10.1093/Brain/Awm156 |
0.488 |
|
| 2007 |
Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT. Expression of APP pathway mRNAs and proteins in Alzheimer's disease. Brain Research. 1161: 116-23. PMID 17586478 DOI: 10.1016/J.Brainres.2007.05.050 |
0.518 |
|
| 2007 |
Kinnecom C, Lev MH, Wendell L, Smith EE, Rosand J, Frosch MP, Greenberg SM. Course of cerebral amyloid angiopathy-related inflammation. Neurology. 68: 1411-6. PMID 17452586 DOI: 10.1212/01.Wnl.0000260066.98681.2E |
0.323 |
|
| 2007 |
Freeman SH, Raju S, Hyman BT, Frosch MP, Irizarry MC. Plasma Abeta levels do not reflect brain Abeta levels. Journal of Neuropathology and Experimental Neurology. 66: 264-71. PMID 17413317 DOI: 10.1097/Nen.0B013E31803D3Ae4 |
0.494 |
|
| 2007 |
Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Archives of Neurology. 64: 431-4. PMID 17353389 DOI: 10.1001/Archneur.64.3.431 |
0.516 |
|
| 2007 |
Prada CM, Garcia-Alloza M, Betensky RA, Zhang-Nunes SX, Greenberg SM, Bacskai BJ, Frosch MP. Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1973-80. PMID 17314293 DOI: 10.1523/Jneurosci.5426-06.2007 |
0.394 |
|
| 2007 |
Frosch MP, Prada CM, Betensky RA, Garcia-Alloza M, Greenberg SM, Bacskai BJ. Effect of passive immunotherapy on the rate of progression of cerebral amyloid angiopathy (caa) in transgenic mice: 126.7 Journal of Neuropathology and Experimental Neurology. 66: 434-435. DOI: 10.1097/01.Jnen.0000268872.45065.C2 |
0.311 |
|
| 2007 |
Frosch MP, Prada CM, Betensky RA, Garcia-Alloza M, Greenberg SM, Bacskai BJ. Effect of passive immunotherapy on the rate of progression of cerebral amyloid angiopathy (caa) in transgenic mice Journal of Neuropathology and Experimental Neurology. 66: 434-435. DOI: 10.1096/Fasebj.21.5.A73-D |
0.311 |
|
| 2006 |
Garcia-Alloza M, Robbins EM, Zhang-Nunes SX, Purcell SM, Betensky RA, Raju S, Prada C, Greenberg SM, Bacskai BJ, Frosch MP. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease. Neurobiology of Disease. 24: 516-24. PMID 17029828 DOI: 10.1016/J.Nbd.2006.08.017 |
0.376 |
|
| 2006 |
Guo S, Wang S, Kim WJ, Lee SR, Frosch MP, Bacskai BJ, Greenberg SM, Lo EH. Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes. Brain Research. 1111: 222-6. PMID 16919608 DOI: 10.1016/J.Brainres.2006.06.041 |
0.334 |
|
| 2006 |
Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, et al. No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathologica. 112: 439-49. PMID 16802167 DOI: 10.1007/S00401-006-0095-3 |
0.528 |
|
| 2006 |
Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT. Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels. Journal of Neuropathology and Experimental Neurology. 65: 508-15. PMID 16772874 DOI: 10.1097/01.Jnen.0000229238.05748.12 |
0.507 |
|
| 2006 |
Zhang-Nunes SX, Maat-Schieman ML, van Duinen SG, Roos RA, Frosch MP, Greenberg SM. The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathology (Zurich, Switzerland). 16: 30-9. PMID 16612980 DOI: 10.1111/J.1750-3639.2006.Tb00559.X |
0.37 |
|
| 2006 |
Klucken J, Ingelsson M, Shin Y, Irizarry MC, Hedley-Whyte ET, Frosch M, Growdon J, McLean P, Hyman BT. Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. Acta Neuropathologica. 111: 101-8. PMID 16482476 DOI: 10.1007/S00401-005-0027-7 |
0.602 |
|
| 2006 |
Robbins EM, Betensky RA, Domnitz SB, Purcell SM, Garcia-Alloza M, Greenberg C, Rebeck GW, Hyman BT, Greenberg SM, Frosch MP, Bacskai BJ. Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 365-71. PMID 16407531 DOI: 10.1523/Jneurosci.3854-05.2006 |
0.526 |
|
| 2006 |
Freeze WM, Greenberg SM, Frosch MP, Jacobs HI, Backes WH, Bacskai B, van Veluw SJ. IC-P-051: BLOOD-BRAIN BARRIER LEAKAGE AND MICROVASCULAR LESIONS IN CEREBRAL AMYLOID ANGIOPATHY: A POSTMORTEM MRI AND HISTOPATHOLOGY STUDY Alzheimer's & Dementia. 14: P50-P50. DOI: 10.1016/J.Jalz.2018.06.1172 |
0.309 |
|
| 2006 |
Prada C, Betensky R, Garcia-Alloza M, Zhang-Nunes S, Greenberg SM, Bacskai BJ, Frosch MP. P4-292: Effect of immunotherapy on the rate of progression of cerebral amyloid angiopathy (CAA) in transgenic mice Alzheimer's & Dementia. 2: S602-S603. DOI: 10.1016/J.Jalz.2006.05.2031 |
0.31 |
|
| 2006 |
Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT. P4-079: Coordinated expression of APP pathway mRNA and protein in AD Alzheimer's & Dementia. 2: S537-S537. DOI: 10.1016/J.Jalz.2006.05.1817 |
0.445 |
|
| 2005 |
Cantuti-Castelvetri I, Klucken J, Ingelsson M, Ramasamy K, McLean PJ, Frosch MP, Hyman BT, Standaert DG. Alpha-synuclein and chaperones in dementia with Lewy bodies. Journal of Neuropathology and Experimental Neurology. 64: 1058-66. PMID 16319716 DOI: 10.1097/01.Jnen.0000190063.90440.69 |
0.435 |
|
| 2005 |
Domnitz SB, Robbins EM, Hoang AW, Garcia-Alloza M, Hyman BT, Rebeck GW, Greenberg SM, Bacskai BJ, Frosch MP. Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 64: 588-94. PMID 16042310 DOI: 10.1097/01.Jnen.0000171644.00180.Fc |
0.555 |
|
| 2005 |
Berezovska O, Lleo A, Herl LD, Frosch MP, Stern EA, Bacskai BJ, Hyman BT. Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3009-17. PMID 15772361 DOI: 10.1523/Jneurosci.0364-05.2005 |
0.487 |
|
| 2004 |
Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron. 44: 227-38. PMID 15473963 DOI: 10.1016/J.Neuron.2004.08.043 |
0.412 |
|
| 2004 |
Lleó A, Berezovska O, Herl L, Raju S, Deng A, Bacskai BJ, Frosch MP, Irizarry M, Hyman BT. Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation. Nature Medicine. 10: 1065-6. PMID 15448688 DOI: 10.1038/Nm1112 |
0.441 |
|
| 2004 |
Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC. Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain. Neurology. 62: 925-31. PMID 15037694 DOI: 10.1212/01.Wnl.0000115115.98960.37 |
0.681 |
|
| 2004 |
Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Annals of Neurology. 55: 250-6. PMID 14755729 DOI: 10.1002/Ana.10810 |
0.33 |
|
| 2004 |
Ingelsson M, Cantuti-Castelvetri I, Ramasamy K, Orne JD, Augustinack JC, Vanderburg CR, Growdon JH, Frosch MP, Irizarry MC, Standaert DG, Hyman BT. P3-229 Analysis of gene expression in the Alzheimer's disease brain Neurobiology of Aging. 25: S420. DOI: 10.1016/S0197-4580(04)81379-4 |
0.498 |
|
| 2003 |
Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron. 40: 1087-93. PMID 14687544 DOI: 10.1016/S0896-6273(03)00787-6 |
0.395 |
|
| 2003 |
Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 4162-7. PMID 12634421 DOI: 10.1073/Pnas.0230450100 |
0.355 |
|
| 2003 |
Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron. 37: 583-95. PMID 12597857 DOI: 10.1016/S0896-6273(03)00024-2 |
0.308 |
|
| 2002 |
Achim C, Auer R, Bergeron C, Cardozo A, Deprez M, de Vos R, Duyckaerts C, Egensperger R, Esiri M, Frosch MP, Giannini C, Goebel HH, Graeber MB, Graham DI, Gray F, et al. Global democratic consensus on neuropathological disease criteria. The Lancet. Neurology. 1: 340. PMID 12849392 DOI: 10.1016/S1474-4422(02)00156-4 |
0.305 |
|
| 2002 |
Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, Debnath ML, Holt DP, Wang Y, Hyman BT. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. Journal of Neuropathology and Experimental Neurology. 61: 797-805. PMID 12230326 DOI: 10.1093/Jnen/61.9.797 |
0.435 |
|
| 2002 |
Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. The American Journal of Pathology. 160: 1655-67. PMID 12000718 DOI: 10.1016/S0002-9440(10)61113-3 |
0.437 |
|
| 2002 |
Mathis CA, Bacskai BJ, Kajdasz ST, McLellan ME, Frosch MP, Hyman BT, Holt DP, Wang Y, Huang GF, Debnath ML, Klunk WE. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorganic & Medicinal Chemistry Letters. 12: 295-8. PMID 11814781 DOI: 10.1016/S0960-894X(01)00734-X |
0.497 |
|
| 2001 |
Scinto LF, Frosch M, Wu CK, Daffner KR, Gedi N, Geula C. Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer's patients. Neurobiology of Aging. 22: 729-36. PMID 11705632 DOI: 10.1016/S0197-4580(01)00235-4 |
0.401 |
|
| 2000 |
Yoo AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xia W, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE, Kim TW. Presenilin-mediated modulation of capacitative calcium entry. Neuron. 27: 561-72. PMID 11055438 DOI: 10.1016/S0896-6273(00)00066-0 |
0.328 |
|
| 2000 |
Chan AW, Tarbell NJ, Black PM, Louis DN, Frosch MP, Ancukiewicz M, Chapman P, Loeffler JS. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery. 47: 623-31; discussion 6. PMID 10981749 DOI: 10.1097/00006123-200009000-00018 |
0.468 |
|
| 2000 |
Sawamura N, Morishima-Kawashima M, Waki H, Kobayashi K, Kuramochi T, Frosch MP, Ding K, Ito M, Kim TW, Tanzi RE, Oyama F, Tabira T, Ando S, Ihara Y. Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin. The Journal of Biological Chemistry. 275: 27901-8. PMID 10846187 DOI: 10.1074/Jbc.M004308200 |
0.326 |
|
| 1999 |
Berezovska O, Frosch M, McLean P, Knowles R, Koo E, Kang D, Shen J, Lu FM, Lux SE, Tonegawa S, Hyman BT. The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons. Brain Research. Molecular Brain Research. 69: 273-80. PMID 10366748 DOI: 10.1016/S0169-328X(99)00119-9 |
0.467 |
|
| 1998 |
Simon DK, Rodriguez ML, Frosch MP, Quackenbush EJ, Feske SK, Natowicz MR. A unique familial leukodystrophy with adult onset dementia and abnormal glycolipid storage: a new lysosomal disease? Journal of Neurology, Neurosurgery, and Psychiatry. 65: 251-4. PMID 9703182 DOI: 10.1136/Jnnp.65.2.251 |
0.336 |
|
| 1997 |
Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261 DOI: 10.1097/00005072-199705000-00004 |
0.462 |
|
| 1997 |
Frosch MP, Collins T, Zhang J, Ahn P, Berezovskaja O, Xia M, Hyman BT, Koo EH. TRANSGENIC MICE EXPRESSING MUTANT AND WILD TYPE HUMAN PRESENILIN-I (PS-1) Journal of Neuropathology and Experimental Neurology. 56: 571. DOI: 10.1097/00005072-199705000-00014 |
0.393 |
|
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