Marla Gearing, PhD, University of Wisconsin - Publications

Pathology Emory University, Atlanta, GA 
The overlap among neurodegenerative diseases, particularly Alzheimer's disease and Parkinson's disease

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang Z, Patel VN, Song X, Xu Y, Kaminski AM, Doan VU, Su G, Liao Y, Mah D, Zhang F, Pagadala V, Wang C, Pedersen LC, Wang L, Hoffman MP, ... Gearing M, et al. Increased 3--sulfated heparan sulfate in Alzheimer's disease brain is associated with genetic risk gene . Science Advances. 9: eadf6232. PMID 37235665 DOI: 10.1126/sciadv.adf6232  0.349
2023 Christensen GM, Li Z, Liang D, Ebelt S, Gearing M, Levey AI, Lah JJ, Wingo AP, Wingo TS, Huels A. Fine particulate air pollution and neuropathology markers of Alzheimer's disease in donors with and without APOE ε4 alleles - results from an autopsy cohort. Medrxiv : the Preprint Server For Health Sciences. PMID 37066193 DOI: 10.1101/2023.04.07.23288288  0.321
2023 Celis K, Moreno MDMM, Rajabli F, Whitehead P, Hamilton-Nelson K, Dykxhoorn DM, Nuytemans K, Wang L, Flanagan M, Weintraub S, Geula C, Gearing M, Dalgard CL, Jin F, Bennett DA, et al. Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37037656 DOI: 10.1002/alz.13075  0.34
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, ... ... Gearing M, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.354
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Gearing M, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.357
2021 Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, et al. Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study. Acta Neuropathologica Communications. 9: 134. PMID 34353357 DOI: 10.1186/s40478-021-01233-3  0.308
2021 Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of Biological Chemistry. 100760. PMID 33965374 DOI: 10.1016/j.jbc.2021.100760  0.34
2021 Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 14: 623659. PMID 33815056 DOI: 10.3389/fnmol.2021.623659  0.31
2021 Griswold AJ, Celis K, Bussies PL, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Beecham GW, Dykxhoorn DM, Nuytemans K, Wang L, Gardner OK, Dorfsman DA, Bigio EH, Mesulam MM, Weintraub S, ... ... Gearing M, et al. Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33522086 DOI: 10.1002/alz.12287  0.302
2020 Higginbotham L, Ping L, Dammer EB, Duong DM, Zhou M, Gearing M, Hurst C, Glass JD, Factor SA, Johnson ECB, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease. Science Advances. 6. PMID 33087358 DOI: 10.1126/sciadv.aaz9360  0.346
2020 Ping L, Kundinger SR, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific Data. 7: 315. PMID 32985496 DOI: 10.1038/s41597-020-00650-8  0.324
2020 Vizcarra JC, Gearing M, Keiser MJ, Glass JD, Dugger BN, Gutman DA. Validation of machine learning models to detect amyloid pathologies across institutions. Acta Neuropathologica Communications. 8: 59. PMID 32345363 DOI: 10.1186/S40478-020-00927-4  0.428
2019 Lee SM, Asress S, Hales CM, Gearing M, Vizcarra JC, Fournier CN, Gutman DA, Chin LS, Li L, Glass JD. TDP-43 cytoplasmic inclusion formation is disrupted in -associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration. Brain Communications. 1: fcz014. PMID 31633109 DOI: 10.1093/braincomms/fcz014  0.329
2019 Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, ... ... Gearing M, et al. Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders. Alzheimer Disease and Associated Disorders. PMID 31513029 DOI: 10.1097/Wad.0000000000000339  0.415
2019 Sycheva M, Sustarich J, Zhang Y, Selvaraju V, Geetha T, Gearing M, Babu JR. Pro-Nerve Growth Factor Induces Activation of RhoA Kinase and Neuronal Cell Death. Brain Sciences. 9. PMID 31430874 DOI: 10.3390/Brainsci9080204  0.321
2019 Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, ... Gearing M, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica. PMID 31327044 DOI: 10.1007/S00401-019-02045-5  0.415
2019 Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H, Kumar V, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW, Hu WT. IL-9 alterations linked to Alzheimer's disease in African Americans. Annals of Neurology. PMID 31271450 DOI: 10.1002/Ana.25543  0.442
2019 Wharton W, Zhao L, Steenland K, Goldstein FC, Schneider JA, Barnes LL, Gearing M, Yasar S. Neurofibrillary Tangles and Conversion to Mild Cognitive Impairment with Certain Antihypertensives. Journal of Alzheimer's Disease : Jad. PMID 31177216 DOI: 10.3233/Jad-190011  0.342
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Gearing M, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9  0.324
2019 Boros BD, Greathouse KM, Gearing M, Herskowitz JH. Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging. Neurobiology of Aging. 73: 92-103. PMID 30339964 DOI: 10.1016/J.Neurobiolaging.2018.09.003  0.392
2019 Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Pak H, Shin R, Huang H, Upadhya S, Zetterberg H, Kumar V, Watts KD, Kippels AJ, Gearing M, Howell J, Parker MW, et al. O2-02-01: DIFFERENT CSF TOTAL AND PHOSPHORYLATED TAU, BUT NOT Aβ, IN OLDER AND YOUNGER AFRICAN AMERICANS AND WHITES Alzheimer's & Dementia. 15: P535-P535. DOI: 10.1016/J.Jalz.2019.06.4457  0.304
2019 Hu WT, Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H, Kumar V, Huang H, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW. P3-620: IL-9 ALTERATIONS ARE LINKED TO ALZHEIMER'S DISEASE IN AFRICAN AMERICANS Alzheimer's & Dementia. 15: P1214-P1214. DOI: 10.1016/J.Jalz.2019.06.3658  0.336
2018 Dai J, Johnson ECB, Dammer EB, Duong DM, Gearing M, Lah JJ, Levey AI, Wingo TS, Seyfried NT. Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 454. PMID 30618606 DOI: 10.3389/Fnmol.2018.00454  0.432
2018 Park K, Lonsberry GE, Gearing M, Levey AI, Desai JP. Viscoelastic Properties of Human Autopsy Brain Tissues as Biomarkers for Alzheimer's Diseases. Ieee Transactions On Bio-Medical Engineering. PMID 30371351 DOI: 10.1109/Tbme.2018.2878555  0.432
2018 Abreha MH, Dammer EB, Ping L, Zhang T, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics. e1800108. PMID 30230243 DOI: 10.1002/Pmic.201800108  0.477
2018 Glass JD, Fournier CN, Gearing M. Reader response: Pathologic Thr tau phosphorylation in CTE and CTE with ALS. Neurology. 91: 578-579. PMID 30224504 DOI: 10.1212/Wnl.0000000000006192  0.306
2018 Hossain MM, Weig B, Reuhl K, Gearing M, Wu LJ, Richardson JR. The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Na 1.6. Experimental Neurology. PMID 30017881 DOI: 10.1016/J.Expneurol.2018.07.005  0.311
2018 Bishof I, Dammer EB, Duong DM, Kundinger S, Gearing M, Lah JJ, Levey AI, Seyfried NT. RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of Biological Chemistry. PMID 29802200 DOI: 10.1074/Jbc.Ra118.001747  0.351
2018 Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Gearing M, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1  0.34
2018 Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29614657 DOI: 10.3233/Jad-170954  0.441
2018 Ping L, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific Data. 5: 180036. PMID 29533394 DOI: 10.1038/Sdata.2018.36  0.441
2018 Zhang Q, Ma C, Gearing M, Wang PG, Chin LS, Li L. Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease. Acta Neuropathologica Communications. 6: 19. PMID 29490708 DOI: 10.1186/S40478-018-0524-2  0.464
2018 Chou CC, Zhang Y, Umoh ME, Vaughan SW, Lorenzini I, Liu F, Sayegh M, Donlin-Asp PG, Chen YH, Duong DM, Seyfried NT, Powers MA, Kukar T, Hales CM, Gearing M, et al. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature Neuroscience. PMID 29311743 DOI: 10.1038/S41593-017-0047-3  0.376
2018 Boros BD, Curtis KA, Greathouse KM, Gearing M, Herskowitz JH. P3-168: Dendritic Spines Provide Cognitive Resilience Against Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1526  0.371
2017 Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT. A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. Embo Molecular Medicine. PMID 29191947 DOI: 10.15252/Emmm.201708202  0.364
2017 Boros BD, Greathouse KM, Gentry EG, Curtis KA, Birchall EL, Gearing M, Herskowitz JH. Dendritic spines provide cognitive resilience against Alzheimer's disease. Annals of Neurology. PMID 28921611 DOI: 10.1002/Ana.25049  0.457
2017 Diner IS, Dooyema J, Gearing M, Walker L, Seyfried NT. Generation of clickable Pittsburgh Compound B for the detection and capture of β-amyloid in Alzheimer's Disease brain. Bioconjugate Chemistry. PMID 28862836 DOI: 10.1021/Acs.Bioconjchem.7B00500  0.305
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Gearing M, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.387
2017 Wharton W, Zhao L, Steenland K, Gearing M, Goldstein FC. [P4-042]: LESS CONVERSION TO AD AND FEWER NEUROFIBRILLARY TANGLES IN MCI PATIENTS TAKING CERTAIN ANTIHYPERTENSIVES Alzheimer's & Dementia. 13: P1272-P1272. DOI: 10.1016/J.Jalz.2017.06.1906  0.396
2017 Boros BD, Gentry EG, Birchall EL, Gearing M, Herskowitz JH. Structural Remodeling Of Dendritic Spines Provides Cognitive Resilience Against Alzheimer’S Disease Pathology Alzheimers & Dementia. 13: 1002. DOI: 10.1016/J.Jalz.2017.06.1389  0.313
2016 Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/J.Cels.2016.11.006  0.451
2016 Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/Pmic.201600057  0.479
2016 Bernstein AI, Lin Y, Street RC, Lin L, Dai Q, Yu L, Bao H, Gearing M, Lah JJ, Nelson PT, He C, Levey AI, Mullé JG, Duan R, Jin P. 5-hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity. Human Molecular Genetics. PMID 27060332 DOI: 10.1093/Hmg/Ddw109  0.457
2016 Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathologica Communications. 4: 14. PMID 26887322 DOI: 10.1186/S40478-016-0277-8  0.454
2016 Gentry EG, Henderson BW, Arrant AE, Gearing M, Feng Y, Riddle NC, Herskowitz JH. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1316-23. PMID 26818518 DOI: 10.1523/Jneurosci.2336-15.2016  0.336
2016 Seyfried NT, Ping L, Dammer EB, Duong DM, Gearing M, Deng Q, Lah JJ, Levey AI. O5-06-02: Proteomic Network Analysis to Find Common Mechanisms Underlying Alzheimer's Disease and PD Alzheimer's & Dementia. 12: P390-P391. DOI: 10.1016/J.Jalz.2016.06.736  0.341
2015 Dunn WD, Gearing M, Park Y, Zhang L, Hanfelt J, Glass JD, Gutman DA. Applicability of digital analysis and imaging technology in neuropathology assessment. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 26577803 DOI: 10.1111/Neup.12273  0.437
2015 Zheng C, Geetha T, Gearing M, Babu JR. Amyloid β-abrogated TrkA ubiquitination in PC12 cells analogous to Alzheimer's disease. Journal of Neurochemistry. 133: 919-25. PMID 25708205 DOI: 10.1111/Jnc.13076  0.447
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Gearing M, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.449
2015 Rangaraju S, Gearing M, Jin LW, Levey A. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 797-808. PMID 25362031 DOI: 10.3233/Jad-141704  0.436
2015 Dammer EB, Lee AK, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 15: 508-19. PMID 25332170 DOI: 10.1002/Pmic.201400189  0.438
2015 Thangiah G, Zheng C, Baker J, Gearing M, Jeganathan R. Polyubiquitination of akt is impaired in Alzheimer’s disease Alzheimers & Dementia. 11: 861. DOI: 10.1016/J.Jalz.2015.08.039  0.342
2015 Dammer EB, Ren R, Duong DM, Lee AK, Gearing M, Lah JJ, Levey AI, Seyfried NT. O4-12-03: Brain phosphoproteome network analysis discriminates Alzheimer's disease from other tauopathies Alzheimer's & Dementia. 11: P300-P300. DOI: 10.1016/J.Jalz.2015.07.415  0.365
2014 Hales C, Neill S, Gearing M, Cooper D, Glass J, Lah J. Late-stage CTE pathology in a retired soccer player with dementia. Neurology. 83: 2307-9. PMID 25378682 DOI: 10.1212/Wnl.0000000000001081  0.366
2014 Diner I, Hales CM, Bishof I, Rabenold L, Duong DM, Yi H, Laur O, Gearing M, Troncoso J, Thambisetty M, Lah JJ, Levey AI, Seyfried NT. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. The Journal of Biological Chemistry. 289: 35296-313. PMID 25355317 DOI: 10.1074/Jbc.M114.562959  0.343
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.462
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Gearing M, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.368
2014 Spears W, Furgerson M, Sweetnam JM, Evans P, Gearing M, Fechheimer M, Furukawa R. Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain. Bmc Neuroscience. 15: 74. PMID 24929931 DOI: 10.1186/1471-2202-15-74  0.412
2014 Wu Z, Guo Z, Gearing M, Chen G. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's [corrected] disease model. Nature Communications. 5: 4159. PMID 24923909 DOI: 10.1038/Ncomms5159  0.373
2014 Deng Q, Holler CJ, Taylor G, Hudson KF, Watkins W, Gearing M, Ito D, Murray ME, Dickson DW, Seyfried NT, Kukar T. FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7802-13. PMID 24899704 DOI: 10.1523/Jneurosci.0172-14.2014  0.31
2014 Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15  0.436
2014 Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, ... ... Gearing M, et al. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43. PMID 24770881 DOI: 10.1007/S00401-014-1282-2  0.351
2014 Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 344-51. PMID 24571648 DOI: 10.1111/Bpa.12133  0.444
2014 Richardson JR, Roy A, Shalat SL, von Stein RT, Hossain MM, Buckley B, Gearing M, Levey AI, German DC. Elevated serum pesticide levels and risk for Alzheimer disease. Jama Neurology. 71: 284-90. PMID 24473795 DOI: 10.1001/Jamaneurol.2013.6030  0.442
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Gearing M, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.348
2013 Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.Jnen.0000435847.59828.Db  0.488
2013 Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, ... ... Gearing M, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110  0.475
2013 Dammer EB, Duong DM, Diner I, Gearing M, Feng Y, Lah JJ, Levey AI, Seyfried NT. Neuron enriched nuclear proteome isolated from human brain. Journal of Proteome Research. 12: 3193-206. PMID 23768213 DOI: 10.1021/Pr400246T  0.32
2013 Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R. NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease. Neuroscience Letters. 547: 16-20. PMID 23669642 DOI: 10.1016/J.Neulet.2013.04.056  0.301
2013 Xu Z, Poidevin M, Li X, Li Y, Shu L, Nelson DL, Li H, Hales CM, Gearing M, Wingo TS, Jin P. Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 7778-83. PMID 23553836 DOI: 10.1073/Pnas.1219643110  0.324
2013 Pranski EL, Dalal NV, Sanford CV, Herskowitz JH, Gearing M, Lazo C, Miller GW, Lah JJ, Levey AI, Betarbet RS. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells. Neurobiology of Disease. 54: 264-79. PMID 23318928 DOI: 10.1016/J.Nbd.2012.12.018  0.311
2012 De Jesús-Cortés HJ, Nogueras-Ortiz CJ, Gearing M, Arnold SE, Vega IE. Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration. Neuroreport. 23: 942-6. PMID 22975846 DOI: 10.1097/Wnr.0B013E32835982Ce  0.414
2012 Hatcher-Martin JM, Gearing M, Steenland K, Levey AI, Miller GW, Pennell KD. Association between polychlorinated biphenyls and Parkinson's disease neuropathology. Neurotoxicology. 33: 1298-304. PMID 22906799 DOI: 10.1016/J.Neuro.2012.08.002  0.381
2012 Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT. Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics. 12: 2455-63. PMID 22718532 DOI: 10.1002/Pmic.201200006  0.349
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Gearing M, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.446
2012 Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI. Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics. Clinical Applications. 6: 201-11. PMID 22532456 DOI: 10.1002/Prca.201100068  0.439
2012 Brotherton TE, Li Y, Cooper D, Gearing M, Julien JP, Rothstein JD, Boylan K, Glass JD. Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS. Proceedings of the National Academy of Sciences of the United States of America. 109: 5505-10. PMID 22431618 DOI: 10.1073/Pnas.1115009109  0.319
2012 Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814  0.377
2012 Poon LW, Woodard JL, Stephen Miller L, Green R, Gearing M, Davey A, Arnold J, Martin P, Siegler IC, Nahapetyan L, Kim YS, Markesbery W. Understanding dementia prevalence among centenarians. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 358-65. PMID 22389466 DOI: 10.1093/Gerona/Glr250  0.303
2012 German D, Roy A, Shalat S, Buckley B, Gearing M, Levey A, Richardson J. P3-128: A DDT metabolite is elevated in the serum of Alzheimer's disease patients Alzheimer's & Dementia. 8: P496-P496. DOI: 10.1016/J.Jalz.2012.05.1348  0.381
2011 Gozal YM, Seyfried NT, Gearing M, Glass JD, Heilman CJ, Wuu J, Duong DM, Cheng D, Xia Q, Rees HD, Fritz JJ, Cooper DS, Peng J, Levey AI, Lah JJ. Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Molecular Neurodegeneration. 6: 82. PMID 22126117 DOI: 10.1186/1750-1326-6-82  0.415
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID). Journal of Neural Transmission (Vienna, Austria : 1996). 118: 1651-7. PMID 21792670 DOI: 10.1007/S00702-011-0690-X  0.314
2011 Page T, Gitcho MA, Mosaheb S, Carter D, Chakraverty S, Perry RH, Bigio EH, Gearing M, Ferrer I, Goate AM, Cairns NJ, Thorpe JR. FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience : Mn. 45: 409-21. PMID 21603978 DOI: 10.1007/S12031-011-9549-8  0.343
2011 Nelson PT, Schmitt FA, Lin Y, Abner EL, Jicha GA, Patel E, Thomason PC, Neltner JH, Smith CD, Santacruz KS, Sonnen JA, Poon LW, Gearing M, Green RC, Woodard JL, et al. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain : a Journal of Neurology. 134: 1506-18. PMID 21596774 DOI: 10.1093/Brain/Awr053  0.38
2011 Gozal YM, Dammer EB, Duong DM, Cheng D, Gearing M, Rees HD, Peng J, Lah JJ, Levey AI. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. Frontiers in Neurology. 2: 24. PMID 21577247 DOI: 10.3389/Fneur.2011.00024  0.371
2011 Dammer EB, Na CH, Xu P, Seyfried NT, Duong DM, Cheng D, Gearing M, Rees H, Lah JJ, Levey AI, Rush J, Peng J. Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. The Journal of Biological Chemistry. 286: 10457-65. PMID 21278249 DOI: 10.1074/Jbc.M110.149633  0.35
2011 Herskowitz JH, Seyfried NT, Gearing M, Kahn RA, Peng J, Levey AI, Lah JJ. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. The Journal of Biological Chemistry. 286: 6117-27. PMID 21147781 DOI: 10.1074/Jbc.M110.167239  0.334
2011 Armstrong RA, Gearing M, Bigio EH, Cruz-Sanchez FF, Duyckaerts C, Mackenzie IR, Perry RH, Skullerud K, Yokoo H, Cairns NJ. The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease. Acta Neuropathologica. 121: 219-28. PMID 20886222 DOI: 10.1007/S00401-010-0753-3  0.357
2010 Herskowitz JH, Seyfried NT, Duong DM, Xia Q, Rees HD, Gearing M, Peng J, Lah JJ, Levey AI. Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. Journal of Proteome Research. 9: 6368-79. PMID 20886841 DOI: 10.1021/Pr100666C  0.395
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Gearing M, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.316
2010 Armstrong RA, Ellis W, Hamilton RL, Mackenzie IR, Hedreen J, Gearing M, Montine T, Vonsattel JP, Head E, Lieberman AP, Cairns NJ. Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 227-39. PMID 20012109 DOI: 10.1007/S00702-009-0350-6  0.363
2010 Rosen RF, Ciliax BJ, Wingo TS, Gearing M, Dooyema J, Lah JJ, Ghiso JA, LeVine H, Walker LC. Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease. Acta Neuropathologica. 119: 221-33. PMID 19690877 DOI: 10.1007/S00401-009-0583-3  0.435
2010 Hwang H, Zhang J, Chung KA, Leverenz JB, Zabetian CP, Peskind ER, Jankovic J, Su Z, Hancock AM, Pan C, Montine TJ, Pan S, Nutt J, Albin R, Gearing M, et al. Glycoproteomics in neurodegenerative diseases. Mass Spectrometry Reviews. 29: 79-125. PMID 19358229 DOI: 10.1002/Mas.20221  0.394
2009 Gozal YM, Duong DM, Gearing M, Cheng D, Hanfelt JJ, Funderburk C, Peng J, Lah JJ, Levey AI. Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. Journal of Proteome Research. 8: 5069-79. PMID 19746990 DOI: 10.1021/Pr900474T  0.486
2009 Yang Q, She H, Gearing M, Colla E, Lee M, Shacka JJ, Mao Z. Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science (New York, N.Y.). 323: 124-7. PMID 19119233 DOI: 10.1126/Science.1166088  0.325
2009 Du Y, Wooten MC, Gearing M, Wooten MW. Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease. Free Radical Biology & Medicine. 46: 492-501. PMID 19071211 DOI: 10.1016/J.Freeradbiomed.2008.11.003  0.378
2008 Betarbet R, Anderson LR, Gearing M, Hodges TR, Fritz JJ, Lah JJ, Levey AI. Fas-associated factor 1 and Parkinson's disease. Neurobiology of Disease. 31: 309-15. PMID 18573343 DOI: 10.1016/J.Nbd.2008.05.006  0.342
2008 Xia Q, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. Journal of Proteome Research. 7: 2845-51. PMID 18510355 DOI: 10.1021/Pr8000496  0.396
2008 Xia Q, Liao L, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Proteomic identification of novel proteins associated with Lewy bodies. Frontiers in Bioscience : a Journal and Virtual Library. 13: 3850-6. PMID 18508479 DOI: 10.2741/2973  0.323
2008 Rosen RF, Farberg AS, Gearing M, Dooyema J, Long PM, Anderson DC, Davis-Turak J, Coppola G, Geschwind DH, Paré JF, Duong TQ, Hopkins WD, Preuss TM, Walker LC. Tauopathy with paired helical filaments in an aged chimpanzee. The Journal of Comparative Neurology. 509: 259-70. PMID 18481275 DOI: 10.1002/Cne.21744  0.45
2008 Shi M, Jin J, Wang Y, Beyer RP, Kitsou E, Albin RL, Gearing M, Pan C, Zhang J. Mortalin: a protein associated with progression of Parkinson disease? Journal of Neuropathology and Experimental Neurology. 67: 117-24. PMID 18219256 DOI: 10.1097/Nen.0B013E318163354A  0.328
2008 Farberg AS, Rosen RF, Gearing M, Pare JF, Walker LC. P4-153: Fibrillar beta-Amyloid in white matter of Alzheimer's disease brain Alzheimer's & Dementia. 4: T715-T715. DOI: 10.1016/J.Jalz.2008.05.2220  0.402
2007 Anderson LR, Betarbet R, Gearing M, Gulcher J, Hicks AA, Stefánsson K, Lah JJ, Levey AI. PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain. Journal of Neuropathology and Experimental Neurology. 66: 955-64. PMID 17917589 DOI: 10.1097/Nen.0B013E3181567F17  0.333
2007 Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Annals of Neurology. 62: 640-7. PMID 17721864 DOI: 10.1002/Ana.21190  0.433
2007 Pan S, Shi M, Jin J, Albin RL, Lieberman A, Gearing M, Lin B, Pan C, Yan X, Kashima DT, Zhang J. Proteomics identification of proteins in human cortex using multidimensional separations and MALDI tandem mass spectrometer. Molecular & Cellular Proteomics : McP. 6: 1818-23. PMID 17644759 DOI: 10.1074/Mcp.M700158-Mcp200  0.338
2007 Hu X, Shi Q, Zhou X, He W, Yi H, Yin X, Gearing M, Levey A, Yan R. Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. The Embo Journal. 26: 2755-67. PMID 17476306 DOI: 10.1038/Sj.Emboj.7601707  0.424
2006 Dodson SE, Gearing M, Lippa CF, Montine TJ, Levey AI, Lah JJ. LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 866-72. PMID 16957580 DOI: 10.1097/01.Jnen.0000228205.19915.20  0.481
2006 Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. The Journal of Biological Chemistry. 281: 10816-24. PMID 16517609 DOI: 10.1074/Jbc.M509079200  0.395
2006 Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ. The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1596-603. PMID 16452683 DOI: 10.1523/Jneurosci.4946-05.2006  0.459
2006 Momeni P, Cairns NJ, Perry RH, Bigio EH, Gearing M, Singleton AB, Hardy J. Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID). Neurobiology of Aging. 27: 778.e1-778.e6. PMID 16005115 DOI: 10.1016/J.Neurobiolaging.2005.03.030  0.402
2006 Ping L, Duong D, Dammer EB, Gearing M, Lah JJ, Levey AI, Seyfried NT. P2-217: INTEGRATED PROTEOMICS AND PHOSPHOPROTEOMICS REVEAL NETWORKS LINKED TO ALZHEIMER'S DISEASE RISK Alzheimer's & Dementia. 14: P752-P752. DOI: 10.1016/J.Jalz.2018.06.905  0.358
2006 Bishof IJ, Dammer EB, Duong D, Gearing M, Lah JJ, Levey AI, Seyfried NT. O2-02-05: RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2649  0.314
2006 Rosen RF, LeVine H, Murphy M, Preuss TM, Ghiso JA, Farberg A, Gearing M, Walker LC. P2-005: Patterns of Aβ accumulation in Alzheimer's and aged primate brain Alzheimer's & Dementia. 2: S233-S233. DOI: 10.1016/J.Jalz.2006.05.842  0.401
2006 Gearing M, Markesbery WR, Poon LW, Burgess M, Green RC. P1-158: Alzheimer's disease in centenarians: Clinicopathologic correlations in the georgia centenarian study Alzheimer's & Dementia. 2: S142-S142. DOI: 10.1016/J.Jalz.2006.05.534  0.405
2005 Mosaheb S, Thorpe JR, Hashemzadeh-Bonehi L, Bigio EH, Gearing M, Cairns NJ. Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease. Acta Neuropathologica. 110: 360-8. PMID 16025283 DOI: 10.1007/S00401-005-1057-X  0.365
2004 Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, et al. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 63: 1376-84. PMID 15505152 DOI: 10.1212/01.Wnl.0000139809.16817.Dd  0.376
2004 Scherzer CR, Offe K, Gearing M, Rees HD, Fang G, Heilman CJ, Schaller C, Bujo H, Levey AI, Lah JJ. Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Archives of Neurology. 61: 1200-5. PMID 15313836 DOI: 10.1001/Archneur.61.8.1200  0.449
2004 Liao L, Cheng D, Wang J, Duong DM, Losik TG, Gearing M, Rees HD, Lah JJ, Levey AI, Peng J. Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. The Journal of Biological Chemistry. 279: 37061-8. PMID 15220353 DOI: 10.1074/Jbc.M403672200  0.477
2004 Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathologica. 108: 213-23. PMID 15170578 DOI: 10.1007/S00401-004-0882-7  0.386
2004 Cairns NJ, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Lee VM, Trojanowski JQ. alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. The American Journal of Pathology. 164: 2153-61. PMID 15161649 DOI: 10.1016/S0002-9440(10)63773-X  0.422
2004 Okun MS, DeLong MR, Hanfelt J, Gearing M, Levey A. Plasma testosterone levels in Alzheimer and Parkinson diseases. Neurology. 62: 411-3. PMID 14872022 DOI: 10.1212/01.Wnl.0000106840.72938.84  0.412
2004 Choi J, Levey AI, Weintraub ST, Rees HD, Gearing M, Chin LS, Li L. Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. The Journal of Biological Chemistry. 279: 13256-64. PMID 14722078 DOI: 10.1074/Jbc.M314124200  0.419
2002 Gearing M, Juncos JL, Procaccio V, Gutekunst CA, Marino-Rodriguez EM, Gyure KA, Ono S, Santoianni R, Krawiecki NS, Wallace DC, Wainer BH. Aggregation of actin and cofilin in identical twins with juvenile-onset dystonia. Annals of Neurology. 52: 465-76. PMID 12325076 DOI: 10.1002/Ana.10319  0.346
2001 Goldstein FC, Ashley AV, Gearing M, Hanfelt J, Penix L, Freedman LJ, Levey AI. Apolipoprotein E and age at onset of Alzheimer's disease in African American patients. Neurology. 57: 1923-5. PMID 11723294 DOI: 10.1212/Wnl.57.10.1923  0.411
2001 Brat DJ, Gearing M, Goldthwaite PT, Wainer BH, Burger PC. Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype. Neuropathology and Applied Neurobiology. 27: 197-205. PMID 11489139 DOI: 10.1046/J.1365-2990.2001.00311.X  0.368
1999 Wolf DS, Gearing M, Snowdon DA, Mori H, Markesbery WR, Mirra SS. Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study. Alzheimer Disease and Associated Disorders. 13: 226-31. PMID 10609672 DOI: 10.1097/00002093-199910000-00009  0.468
1999 Tsuang D, Larson EB, Bowen J, McCormick W, Teri L, Nochlin D, Leverenz JB, Peskind ER, Lim A, Raskind MA, Thompson ML, Mirra SS, Gearing M, Schellenberg GD, Kukull W. The utility of apolipoprotein E genotyping in the diagnosis of Alzheimer disease in a community-based case series. Archives of Neurology. 56: 1489-95. PMID 10593304 DOI: 10.1001/Archneur.56.12.1489  0.417
1999 Heyman A, Fillenbaum GG, Gearing M, Mirra SS, Welsh-Bohmer KA, Peterson B, Pieper C. Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX. Neurology. 52: 1839-44. PMID 10371532 DOI: 10.1212/Wnl.52.9.1839  0.432
1999 Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629 DOI: 10.1097/00005072-199904000-00004  0.393
1999 Gearing M, Lynn M, Mirra SS. Neurofibrillary pathology in Alzheimer disease with Lewy bodies: two subgroups. Archives of Neurology. 56: 203-8. PMID 10025425 DOI: 10.1001/Archneur.56.2.203  0.454
1999 Gearing M, Schultz A, Ghetti B, Piccardo P, Mirra SS. Neuropathological Changes And Apolipoprotein E Genotype In AlzheimerʼS Disease (Ad) With Concomitant Lewy Bodies: An Alpha-Synuclein Immunohistochemical Study Journal of Neuropathology and Experimental Neurology. 58: 552. DOI: 10.1097/00005072-199905000-00185  0.382
1998 Heyman A, Fillenbaum GG, Welsh-Bohmer KA, Gearing M, Mirra SS, Mohs RC, Peterson BL, Pieper CF. Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer's Disease. Neurology. 51: 159-62. PMID 9674796 DOI: 10.1212/Wnl.51.1.159  0.451
1998 Berg L, McKeel DW, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM, Price JL, Gearing M, Mirra SS, Saunders AM. Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Archives of Neurology. 55: 326-35. PMID 9520006 DOI: 10.1001/Archneur.55.3.326  0.467
1997 Gearing M, Levey AI, Mirra SS. Diffuse plaques in the striatum in Alzheimer disease (AD): relationship to the striatal mosaic and selected neuropeptide markers. Journal of Neuropathology and Experimental Neurology. 56: 1363-70. PMID 9413285 DOI: 10.1097/00005072-199712000-00011  0.322
1997 Mirra SS, Gearing M, Nash F. Neuropathologic assessment of Alzheimer's disease. Neurology. 49: S14-6. PMID 9310508 DOI: 10.1212/Wnl.49.3_Suppl_3.S14  0.447
1997 Welsh-Bohmer KA, Gearing M, Saunders AM, Roses AD, Mirra S. Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Annals of Neurology. 42: 319-25. PMID 9307253 DOI: 10.1002/Ana.410420308  0.436
1997 Gearing M, Tigges J, Mori H, Mirra SS. beta-Amyloid (A beta) deposition in the brains of aged orangutans. Neurobiology of Aging. 18: 139-46. PMID 9258890 DOI: 10.1016/S0197-4580(97)00012-2  0.378
1997 Mirra SS, Gearing M. Brain infarction and the clinical expression of Alzheimer disease. Jama. 278: 113; author reply 11. PMID 9214519 DOI: 10.1001/Jama.1997.03550020045022  0.475
1997 Schneider JA, Watts RL, Gearing M, Brewer RP, Mirra SS. Corticobasal degeneration: neuropathologic and clinical heterogeneity. Neurology. 48: 959-69. PMID 9109885 DOI: 10.1212/Wnl.48.4.959  0.319
1997 Shao Y, Gearing M, Mirra SS. Astrocyte-apolipoprotein E associations in senile plaques in Alzheimer disease and vascular lesions: a regional immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 56: 376-81. PMID 9100668 DOI: 10.1097/00005072-199704000-00006  0.425
1997 Ishii K, Tamaoka A, Mizusawa H, Shoji S, Ohtake T, Fraser PE, Takahashi H, Tsuji S, Gearing M, Mizutani T, Yamada S, Kato M, St George-Hyslop PH, Mirra SS, Mori H. Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease. Brain Research. 748: 250-2. PMID 9067471 DOI: 10.1016/S0006-8993(96)01363-7  0.391
1997 Mirra SS, Gearing M, Jones R, Evatt ML, Young K, Piccardo P, Ghetti B. PRION PROTEIN (PrP) AMYLOID COEXISTS WITH NEUROFIBRILLARY TANGLES AND LEWY BODIES IN A PATIENT FROM A NEW FAMILY OF GERSTMANN STRÄUSSLER SCHEINKER DISEASE (GSS) Journal of Neuropathology and Experimental Neurology. 56: 596. DOI: 10.1097/00005072-199705000-00115  0.365
1996 Gearing M, Mori H, Mirra SS. Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease. Annals of Neurology. 39: 395-9. PMID 8602762 DOI: 10.1002/Ana.410390320  0.367
1996 Gearing M, Mirra SS, Hedreen JC, Sumi SM, Hansen LA, Heyman A. Reply from the Authors AD neuropathology Neurology. 46: 1186-1187. DOI: 10.1212/Wnl.46.4.1186-C  0.424
1995 Gearing M, Mirra SS, Hedreen JC, Sumi SM, Hansen LA, Heyman A. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease. Neurology. 45: 461-6. PMID 7898697 DOI: 10.1212/Wnl.45.3.461  0.479
1995 Davis PC, Gearing M, Gray L, Mirra SS, Morris JC, Edland SD, Lin T, Heyman A. The CERAD experience, Part VIII: Neuroimaging-neuropathology correlates of temporal lobe changes in Alzheimer's disease. Neurology. 45: 178-9. PMID 7824112 DOI: 10.1212/Wnl.45.1.178  0.435
1995 Kim H, Gearing M, Mirra SS. Ubiquitin-positive CA2/3 neurites in hippocampus coexist with cortical Lewy bodies. Neurology. 45: 1768-70. PMID 7675245 DOI: 10.1212/Wnl.45.9.1768  0.396
1995 Schneider JA, Gearing M, Robbins RS, de l'Aune W, Mirra SS. Apolipoprotein E genotype in diverse neurodegenerative disorders. Annals of Neurology. 38: 131-5. PMID 7611717 DOI: 10.1002/Ana.410380122  0.463
1995 Gearing M, Schneider JA, Robbins RS, Hollister RD, Mori H, Games D, Hyman BT, Mirra SS. Regional variation in the distribution of apolipoprotein E and A beta in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology. 54: 833-41. PMID 7595656 DOI: 10.1097/00005072-199511000-00010  0.42
1995 Gearing M, Schneider JA, Rebeck GW, Hyman BT, Mirra SS. Alzheimer's disease with and without coexisting Parkinson's disease changes: apolipoprotein E genotype and neuropathologic correlates. Neurology. 45: 1985-90. PMID 7501146 DOI: 10.1212/Wnl.45.11.1985  0.448
1994 Gearing M, Olson DA, Watts RL, Mirra SS. Progressive supranuclear palsy: neuropathologic and clinical heterogeneity. Neurology. 44: 1015-24. PMID 8208392 DOI: 10.1212/Wnl.44.6.1015  0.326
1994 Mirra SS, Gearing M, McKeel DW, Crain BJ, Hughes JP, van Belle G, Heyman A. Interlaboratory comparison of neuropathology assessments in Alzheimer's disease: a study of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Journal of Neuropathology and Experimental Neurology. 53: 303-15. PMID 8176413 DOI: 10.1097/00005072-199405000-00012  0.472
1994 Gearing M, Rebeck GW, Hyman BT, Tigges J, Mirra SS. Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 9382-6. PMID 7937774 DOI: 10.1073/Pnas.91.20.9382  0.464
1993 Shoffner JM, Brown MD, Torroni A, Lott MT, Cabell MF, Mirra SS, Beal MF, Yang CC, Gearing M, Salvo R. Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. Genomics. 17: 171-84. PMID 8104867 DOI: 10.1006/Geno.1993.1299  0.378
1993 Gearing M, Wilson RW, Unger ER, Shelton ER, Chan HW, Masters CL, Beyreuther K, Mirra SS. Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 52: 22-30. PMID 7678853 DOI: 10.1097/00005072-199301000-00004  0.391
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