Richard J. Wurtman - Publications

Massachusetts Institute of Technology, Cambridge, MA, United States 
Cell membrane

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Year Citation  Score
2015 Cansev M, Orhan F, Yaylagul EO, Isik E, Turkyilmaz M, Aydin S, Gumus A, Sevinc C, Coskun N, Ulus IH, Wurtman RJ. Evidence for the existence of pyrimidinergic transmission in rat brain. Neuropharmacology. 91: 77-86. PMID 25541414 DOI: 10.1016/j.neuropharm.2014.12.019  0.775
2012 van Wijk N, Watkins CJ, Hageman RJ, Sijben JC, Kamphuis PG, Wurtman RJ, Broersen LM. Combined dietary folate, vitamin B-12, and vitamin B-6 intake influences plasma docosahexaenoic acid concentration in rats. Nutrition & Metabolism. 9: 49. PMID 22647268 DOI: 10.1186/1743-7075-9-49  0.485
2012 van Wijk N, Watkins CJ, Böhlke M, Maher TJ, Hageman RJ, Kamphuis PJ, Broersen LM, Wurtman RJ. Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets. The British Journal of Nutrition. 107: 1408-12. PMID 21917195 DOI: 10.1017/S0007114511004570  0.604
2010 Wurtman RJ, Cansev M, Sakamoto T, Ulus I. Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses. Nutrition Reviews. 68: S88-101. PMID 21091953 DOI: 10.1111/j.1753-4887.2010.00344.x  0.775
2009 Wurtman RJ, Cansev M, Sakamoto T, Ulus IH. Use of phosphatide precursors to promote synaptogenesis. Annual Review of Nutrition. 29: 59-87. PMID 19400698 DOI: 10.1146/annurev-nutr-080508-141059  0.775
2009 Wurtman RJ, Cansev M, Ulus IH. Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides. The Journal of Nutrition, Health & Aging. 13: 189-97. PMID 19262950 DOI: 10.1007/s12603-009-0056-3  0.775
2009 Cansev M, Marzloff G, Sakamoto T, Ulus IH, Wurtman RJ. Giving uridine and/or docosahexaenoic acid orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups. Developmental Neuroscience. 31: 181-92. PMID 19145070 DOI: 10.1159/000193394  0.769
2009 Wurtman RJ, Cansev M, Sakamoto T, Ulus IH. Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. World Review of Nutrition and Dietetics. 99: 71-96. PMID 19136840 DOI: 10.1159/000192998  0.775
2008 Cansev M, Ulus IH, Wang L, Maher TJ, Wurtman RJ. Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease. Neuroscience Research. 62: 206-9. PMID 18761383 DOI: 10.1016/j.neures.2008.07.005  0.781
2008 Cansev M, Wurtman RJ, Sakamoto T, Ulus IH. Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: S153-68. PMID 18631994 DOI: 10.1016/j.jalz.2007.10.005  0.775
2008 Holguin S, Martinez J, Chow C, Wurtman R. Dietary uridine enhances the improvement in learning and memory produced by administering DHA to gerbils. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3938-46. PMID 18606862 DOI: 10.1096/fj.08-112425  0.776
2008 Holguin S, Huang Y, Liu J, Wurtman R. Chronic administration of DHA and UMP improves the impaired memory of environmentally impoverished rats. Behavioural Brain Research. 191: 11-6. PMID 18423905 DOI: 10.1016/j.bbr.2008.02.042  0.783
2007 Sakamoto T, Cansev M, Wurtman RJ. Oral supplementation with docosahexaenoic acid and uridine-5'-monophosphate increases dendritic spine density in adult gerbil hippocampus. Brain Research. 1182: 50-9. PMID 17950710 DOI: 10.1016/j.brainres.2007.08.089  0.753
2007 Cansev M, Wurtman RJ. Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine, increases brain phosphatide and synaptic protein levels in gerbils. Neuroscience. 148: 421-31. PMID 17683870 DOI: 10.1016/j.neuroscience.2007.06.016  0.753
2007 Wang L, Maher TJ, Wurtman RJ. Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1227-32. PMID 17218538 DOI: 10.1096/Fj.06-7495Com  0.525
2007 Wang L, Albrecht MA, Wurtman RJ. Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat. Brain Research. 1133: 42-8. PMID 17184749 DOI: 10.1016/j.brainres.2006.11.048  0.323
2006 Teather LA, Wurtman RJ. Chronic administration of UMP ameliorates the impairment of hippocampal-dependent memory in impoverished rats. The Journal of Nutrition. 136: 2834-7. PMID 17056809 DOI: 10.1093/Jn/136.11.2834  0.726
2006 Teather LA, Afonso VM, Wurtman RJ. Inhibition of platelet-activating factor receptors in hippocampal plasma membranes attenuates the inflammatory nociceptive response in rats. Brain Research. 1097: 230-3. PMID 16774744 DOI: 10.1016/j.brainres.2006.03.036  0.733
2006 Ulus IH, Watkins CJ, Cansev M, Wurtman RJ. Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release. Cellular and Molecular Neurobiology. 26: 563-77. PMID 16636900 DOI: 10.1007/s10571-006-9004-5  0.774
2006 Wurtman RJ, Ulus IH, Cansev M, Watkins CJ, Wang L, Marzloff G. Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally. Brain Research. 1088: 83-92. PMID 16631143 DOI: 10.1016/j.brainres.2006.03.019  0.769
2006 Pooler AM, Xi SC, Wurtman RJ. The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons. Journal of Neurochemistry. 97: 716-23. PMID 16573653 DOI: 10.1111/j.1471-4159.2006.03763.x  0.677
2006 O'rourke D, Wurtman J, Brzezinski A, Abou‐Nader T, Marchant P, Wurtman RJ. Treatment of Seasonal Affective Disorder with d‐Fenfluramine Annals of the New York Academy of Sciences. 499: 329-330. DOI: 10.1111/J.1749-6632.1987.Tb36227.X  0.507
2005 Cansev M, Watkins CJ, van der Beek EM, Wurtman RJ. Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils. Brain Research. 1058: 101-8. PMID 16126180 DOI: 10.1016/j.brainres.2005.07.054  0.776
2005 Wang L, Pooler AM, Albrecht MA, Wurtman RJ. Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats. Journal of Molecular Neuroscience : Mn. 27: 137-45. PMID 16055952 DOI: 10.1385/JMN:27:1:137  0.688
2005 Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]. Neuroscience. 134: 207-14. PMID 15939540 DOI: 10.1016/j.neuroscience.2005.03.050  0.677
2005 Brzezinski A, Vangel MG, Wurtman RJ, Norrie G, Zhdanova I, Ben-Shushan A, Ford I. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Medicine Reviews. 9: 41-50. PMID 15649737 DOI: 10.1016/j.smrv.2004.06.004  0.679
2005 Teather LA, Wurtman RJ. Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 39-43. PMID 15647594 DOI: 10.1101/lm.83905  0.726
2005 Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Erratum to “Uridine enhances neurite outgrowth in nerve growth factor-differentiated pheochromocytoma cells” [Neuroscience 134 (2005) 207–214] Neuroscience. 135: 657. DOI: 10.1016/J.Neuroscience.2005.07.044  0.677
2004 Pooler AM, Arjona AA, Lee RK, Wurtman RJ. Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia. Neuroscience Letters. 362: 127-30. PMID 15193769 DOI: 10.1016/j.neulet.2004.03.013  0.683
2004 Wang P, Saraswati S, Guan Z, Watkins CJ, Wurtman RJ, Littleton JT. A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4518-29. PMID 15140922 DOI: 10.1523/JNEUROSCI.0542-04.2004  0.487
2004 Amer A, Breu J, McDermott J, Wurtman RJ, Maher TJ. 5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats. Pharmacology, Biochemistry, and Behavior. 77: 137-43. PMID 14724051 DOI: 10.1016/j.pbb.2003.10.011  0.504
2003 Teather LA, Wurtman RJ. Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 711-7. PMID 12787861 DOI: 10.1016/S0278-5846(03)00086-1  0.726
2003 Richardson UI, Watkins CJ, Pierre C, Ulus IH, Wurtman RJ. Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells. Brain Research. 971: 161-7. PMID 12706232 DOI: 10.1016/S0006-8993(03)02333-3  0.76
2003 Teather LA, Wurtman RJ. Cyclooxygenase-2 mediates platelet-activating factor-induced prostaglandin E2 release from rat primary astrocytes. Neuroscience Letters. 340: 177-80. PMID 12672535 DOI: 10.1016/S0304-3940(03)00129-0  0.726
2002 Teather LA, Magnusson JE, Chow CM, Wurtman RJ. Environmental conditions influence hippocampus-dependent behaviours and brain levels of amyloid precursor protein in rats. The European Journal of Neuroscience. 16: 2405-15. PMID 12492435 DOI: 10.1046/j.1460-9568.2002.02416.x  0.738
2002 Teather LA, Magnusson JE, Wurtman RJ. Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats. Psychopharmacology. 163: 430-3. PMID 12373444 DOI: 10.1007/s00213-002-1039-9  0.726
2002 Arjona AA, Pooler AM, Lee RK, Wurtman RJ. Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. Brain Research. 951: 135-40. PMID 12231467 DOI: 10.1016/S0006-8993(02)03153-0  0.687
2002 Teather LA, Lee RK, Wurtman RJ. Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures. Brain Research. 946: 87-95. PMID 12133598 DOI: 10.1016/S0006-8993(02)02866-4  0.733
2001 Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia. The Journal of Clinical Endocrinology and Metabolism. 86: 4727-30. PMID 11600532 DOI: 10.1210/jcem.86.10.7901  0.603
2000 Balcioglu A, Wurtman RJ. Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid. Neuropharmacology. 39: 2352-9. PMID 10974319 DOI: 10.1016/S0028-3908(00)00083-6  0.691
2000 Wurtman RJ, Regan M, Ulus I, Yu L. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochemical Pharmacology. 60: 989-92. PMID 10974208 DOI: 10.1016/S0006-2952(00)00436-6  0.703
2000 Balcioglu A, Wurtman RJ. Striatal serotonin receptors and dopamine release. Journal of Neurochemistry. 75: 886. PMID 10899968 DOI: 10.1046/J.1471-4159.2000.0750886.X  0.691
2000 Wang C, Wurtman RJ, Lee RK. Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40). Brain Research. 865: 157-67. PMID 10821917 DOI: 10.1016/S0006-8993(00)02183-1  0.716
2000 Ulus IH, Maher TJ, Wurtman RJ. Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochemical Pharmacology. 59: 1611-21. PMID 10799660 DOI: 10.1016/S0006-2952(00)00306-3  0.752
1999 Li J, Wurtman RJ. Heterogeneous long chain acyl-CoA synthetases control distribution of individual fatty acids in newly-formed glycerolipids of neuronal cells undergoing neurite outgrowth. Neurochemical Research. 24: 739-50. PMID 10447457 DOI: 10.1023/A:1020727429052  0.704
1999 Zhdanova IV, Wurtman RJ, Wagstaff J. Effects of a low dose of melatonin on sleep in children with Angelman syndrome. Journal of Pediatric Endocrinology & Metabolism : Jpem. 12: 57-67. PMID 10392349 DOI: 10.1515/JPEM.1999.12.1.57  0.594
1999 Knapp S, Wurtman RJ. Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine. Brain Research. 822: 52-9. PMID 10082883 DOI: 10.1016/S0006-8993(99)01072-0  0.448
1999 Li J, Wurtman RJ. Mechanisms whereby nerve growth factor increases diacylglycerol levels in differentiating PC12 cells. Brain Research. 818: 252-9. PMID 10082810 DOI: 10.1016/S0006-8993(98)01280-3  0.704
1999 Maher TJ, Ulus IH, Wurtman RJ. Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines. Lancet. 353: 38. PMID 10023954 DOI: 10.1016/S0140-6736(05)74870-4  0.759
1999 Lee RKK, Knapp S, Wurtman RJ. Prostaglandin E2Stimulates Amyloid Precursor Protein Gene Expression: Inhibition by Immunosuppressants The Journal of Neuroscience. 19: 940-947. DOI: 10.1523/JNEUROSCI.19-03-00940.1999  0.448
1999 Maher TJ, Ulus IH, Wurtman RJ. Does phentermine inhibit monoamine oxidase? The Lancet. 353: 1362-1363. DOI: 10.1016/S0140-6736(05)74359-2  0.409
1998 Zhdanova IV, Wurtman RJ, Balcioglu A, Kartashov AI, Lynch HJ. Endogenous melatonin levels and the fate of exogenous melatonin: age effects. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B293-8. PMID 18314560 DOI: 10.1093/GERONA/53A.4.B293  0.773
1998 Wurtman J, Wurtman R, Mark S, Tsay R, Gilbert W, Growdon J. d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects. The International Journal of Eating Disorders. 4: 89-99. PMID 11540865 DOI: 10.1002/1098-108X(198502)4:1<89::AID-EAT2260040110>3.0.CO;2-D  0.49
1998 Müller D, Nitsch RM, Wurtman RJ, Hoyer S. Streptozotocin increases free fatty acids and decreases phospholipids in rat brain. Journal of Neural Transmission (Vienna, Austria : 1996). 105: 1271-81. PMID 9928896 DOI: 10.1007/s007020050130  0.452
1998 Balcioglu A, Wurtman RJ. Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: in vivo microdialysis study in conscious animals. Brain Research. 813: 67-72. PMID 9824670 DOI: 10.1016/S0006-8993(98)01003-8  0.691
1998 Li J, Wurtman RJ. Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells. Brain Research. 803: 44-53. PMID 9729268 DOI: 10.1016/S0006-8993(98)00595-2  0.704
1998 Wurtman RJ, Zhdanova II. Oral melatonin in neurologically disabled children. Lancet. 351: 1963-4; author reply. PMID 9654294 DOI: 10.1016/S0140-6736(05)78653-0  0.594
1998 Araki W, Wurtman RJ. Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells. Brain Research. Molecular Brain Research. 56: 169-77. PMID 9602112 DOI: 10.1016/S0169-328X(98)00050-3  0.552
1998 Araki W, Wurtman RJ. How is membrane phospholipid biosynthesis controlled in neural tissues? Journal of Neuroscience Research. 51: 667-74. PMID 9545081 DOI: 10.1002/(SICI)1097-4547(19980315)51:6<667::AID-JNR1>3.0.CO;2-9  0.552
1997 Zhdanova IV, Wurtman RJ. Efficacy of melatonin as a sleep-promoting agent. Journal of Biological Rhythms. 12: 644-50. PMID 9406040 DOI: 10.1177/074873049701200620  0.594
1997 Erfurth A, Wurtman RJ. Sensitive measurement of agonist-stimulated [3H]inositol monophosphate accumulation in rat cortical miniprisms. Brain Research. Brain Research Protocols. 1: 139-44. PMID 9385077 DOI: 10.1016/S1385-299X(96)00022-0  0.571
1997 Slack BE, Breu J, Muchnicki L, Wurtman RJ. Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C. The Biochemical Journal. 327: 245-9. PMID 9355759 DOI: 10.1042/BJ3270245  0.588
1997 Araki W, Wurtman RJ. Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 94: 11946-50. PMID 9342342 DOI: 10.1073/pnas.94.22.11946  0.552
1997 Conlay LA, Conant JA, deBros F, Wurtman R. Caffeine alters plasma adenosine levels. Nature. 389: 136. PMID 9296490 DOI: 10.1038/38160  0.645
1997 Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. 1971. Obesity Research. 5: 377-80. PMID 9285847 DOI: 10.1002/J.1550-8528.1997.TB00567.X  0.526
1997 Nitsch RM, Deng A, Wurtman RJ, Growdon JH. Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. Journal of Neurochemistry. 69: 704-12. PMID 9231730 DOI: 10.1046/j.1471-4159.1997.69020704.x  0.622
1997 Lee RK, Araki W, Wurtman RJ. Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. Proceedings of the National Academy of Sciences of the United States of America. 94: 5422-6. PMID 9144253 DOI: 10.1073/pnas.94.10.5422  0.552
1996 Marshall DL, De Micheli E, Bogdanov MB, Wurtman RJ. Effects of ethanolamine (Etn) administration on Etn and choline (Ch) levels in plasma, brain extracellular fluid (ECF) and brain tissue, and on brain phospholipid levels in rats: an in vivo study. Neuroscience Research Communications. 18: 87-96. PMID 11540106 DOI: 10.1002/(SICI)1520-6769(199603)18:2<87::AID-NRC144>3.0.CO;2-C  0.619
1996 Petryniak MA, Wurtman RJ, Slack BE. Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism. The Biochemical Journal. 320: 957-63. PMID 9003386 DOI: 10.1042/BJ3200957  0.586
1996 Bogdanov MB, Tjurmina OA, Wurtman RJ. Consumption of a high dietary dose of monosodium glutamate fails to affect extracellular glutamate levels in the hypothalamic arcuate nucleus of adult rats. Brain Research. 736: 76-81. PMID 8930311 DOI: 10.1016/0006-8993(96)00679-8  0.776
1996 Zhdanova IV, Wurtman RJ, Morabito C, Piotrovska VR, Lynch HJ. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 19: 423-31. PMID 8843534 DOI: 10.1093/SLEEP/19.5.423  0.599
1996 Farber SA, Savci V, Wei A, Slack BE, Wurtman RJ. Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons. Brain Research. 723: 90-9. PMID 8813385 DOI: 10.1016/0006-8993(96)00221-1  0.775
1996 Nitsch RM, Deng M, Growdon JH, Wurtman RJ. Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion. The Journal of Biological Chemistry. 271: 4188-94. PMID 8626761 DOI: 10.1074/jbc.271.8.4188  0.622
1996 Spiers PA, Myers D, Hochanadel GS, Lieberman HR, Wurtman RJ. Citicoline improves verbal memory in aging. Archives of Neurology. 53: 441-8. PMID 8624220 DOI: 10.1001/archneur.1996.00550050071026  0.447
1996 Lee RK, Jimenez J, Cox AJ, Wurtman RJ. Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats. Annals of the New York Academy of Sciences. 777: 338-43. PMID 8624110 DOI: 10.1111/j.1749-6632.1996.tb34443.x  0.491
1996 Nitsch RM, Wurtman RJ, Growdon JH. Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden. Annals of the New York Academy of Sciences. 777: 175-82. PMID 8624081 DOI: 10.1111/j.1749-6632.1996.tb34416.x  0.622
1996 Lees RK, Araki W, Wurtman RJ. 808 Regulation of amyloid precursor protein processing and synthesis by receptor-mediated signal transduction Neurobiology of Aging. 17: S201. DOI: 10.1016/S0197-4580(96)80810-4  0.552
1995 Slack BE, Breu J, Livneh E, Eldar H, Wurtman RJ. Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha. The Biochemical Journal. 305: 621-6. PMID 7832781 DOI: 10.1042/BJ3050621  0.577
1995 Savci V, Wurtman RJ. Effect of cytidine on membrane phospholipid synthesis in rat striatal slices. Journal of Neurochemistry. 64: 378-84. PMID 7798935 DOI: 10.1046/j.1471-4159.1995.64010378.x  0.772
1995 Zhdanova IV, Wurtman RJ, Lynch HJ, Ives JR, Dollins AB, Morabito C, Matheson JK, Schomer DL. Sleep-inducing effects of low doses of melatonin ingested in the evening. Clinical Pharmacology and Therapeutics. 57: 552-8. PMID 7768078 DOI: 10.1016/0009-9236(95)90040-3  0.774
1995 Stoll AL, Renshaw PF, De Micheli E, Wurtman R, Pillay SS, Cohen BM. Choline ingestion increases the resonance of choline-containing compounds in human brain: an in vivo proton magnetic resonance study. Biological Psychiatry. 37: 170-4. PMID 7727625 DOI: 10.1016/0006-3223(94)00120-R  0.629
1995 Nitsch RM, Rebeck GW, Deng M, Richardson UI, Tennis M, Schenk DB, Vigo-Pelfrey C, Lieberburg I, Wurtman RJ, Hyman BT. Cerebrospinal fluid levels of amyloid beta-protein in Alzheimer's disease: inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Annals of Neurology. 37: 512-8. PMID 7717688 DOI: 10.1002/Ana.410370414  0.51
1995 Dollins AB, Krock LP, Storm WF, Wurtman RJ, Lieberman HR. L-tyrosine ameliorates some effects of lower body negative pressure stress. Physiology & Behavior. 57: 223-30. PMID 7716196 DOI: 10.1016/0031-9384(94)00278-D  0.78
1995 Slack BE, Breu J, Petryniak MA, Srivastava K, Wurtman RJ. Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor. The Journal of Biological Chemistry. 270: 8337-44. PMID 7713942 DOI: 10.1074/jbc.270.14.8337  0.584
1995 Lee RK, Wurtman RJ, Cox AJ, Nitsch RM. Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 92: 8083-7. PMID 7644542 DOI: 10.1073/pnas.92.17.8083  0.513
1995 López-Coviella I, Agut J, Savci V, Ortiz JA, Wurtman RJ. Evidence that 5'-cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels. Journal of Neurochemistry. 65: 889-94. PMID 7616250 DOI: 10.1046/j.1471-4159.1995.65020889.x  0.787
1995 Wurtman RJ, Zhdanova I. Improvement of sleep quality by melatonin. Lancet. 346: 1491. PMID 7491013 DOI: 10.1016/S0140-6736(95)92509-0  0.594
1995 Nitsch RM, Marinescu V, Postle BR, Corkin S, Wurtman RJ. Eight Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging. The Neurobiology of Alzheimer's Disease, Zurich, Switzerland, February 17-19, 1995 Amyloid. 2: 204-212. DOI: 10.3109/13506129509036928  0.502
1995 Farber S, Nitsch R, Schulz J, Wurtman R. Regulated secretion of beta-amyloid precursor protein in rat brain The Journal of Neuroscience. 15: 7442-7451. DOI: 10.1523/JNEUROSCI.15-11-07442.1995  0.727
1995 Ives J, Mainwaring N, Matheson J, Zhdanova I, Wurtman R, Schomer D. Remote ambulaltory data acquisition with internet transfer of large EEG/ sleep files for replay and analysis during a pilot melatonin drug studies Electroencephalography and Clinical Neurophysiology. 95: P31. DOI: 10.1016/0013-4694(95)97985-a  0.554
1994 Dollins AB, Zhdanova IV, Wurtman RJ, Lynch HJ, Deng MH. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proceedings of the National Academy of Sciences of the United States of America. 91: 1824-8. PMID 8127888 DOI: 10.1073/PNAS.91.5.1824  0.779
1994 Nitsch RM, Slack BE, Farber SA, Schulz JG, Deng M, Kim C, Borghesani PR, Korver W, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices. Journal of Neural Transmission. Supplementum. 44: 21-7. PMID 7897393 DOI: 10.1007/978-3-7091-9350-1_2  0.781
1994 Erfurth A, Gardier AM, Ribeiro E, Wurtman RJ. Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms. Brain Research. 665: 107-14. PMID 7882002 DOI: 10.1016/0006-8993(94)91158-4  0.688
1994 Farber S, Nitsch R, Growdon J, Wurtman R. 24. A novel approach to study the regulated release of secretory proteins from brain slices Journal of Neuroscience Methods. 52: A11-A12. DOI: 10.1016/0165-0270(94)90084-1  0.731
1993 Nitsch RM, Farber SA, Growdon JH, Wurtman RJ. Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 90: 5191-3. PMID 8506366 DOI: 10.1073/PNAS.90.11.5191  0.731
1993 Farber SA, Kischka U, Marshall DL, Wurtman RJ. Potentiation by choline of basal and electrically evoked acetylcholine release, as studied using a novel device which both stimulates and perfuses rat corpus striatum. Brain Research. 607: 177-84. PMID 8481795 DOI: 10.1016/0006-8993(93)91504-L  0.593
1993 Dollins AB, Lynch HJ, Wurtman RJ, Deng MH, Lieberman HR. Effects of illumination on human nocturnal serum melatonin levels and performance. Physiology & Behavior. 53: 153-60. PMID 8434055 DOI: 10.1016/0031-9384(93)90024-A  0.781
1993 Kaakkola S, Wurtman RJ. Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. Journal of Neurochemistry. 60: 137-44. PMID 8417137 DOI: 10.1111/j.1471-4159.1993.tb05831.x  0.593
1993 Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ. Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. Neuroscience Letters. 161: 191-4. PMID 8272265 DOI: 10.1016/0304-3940(93)90291-R  0.693
1993 Agut J, Lopez G-Coviella I, Ortiz JA, Wurtman RJ. Oral cytidine 5'-diphosphate choline administration to rats increases brain phospholipid levels. Annals of the New York Academy of Sciences. 695: 318-20. PMID 8239304 DOI: 10.1111/j.1749-6632.1993.tb23075.x  0.304
1993 Holmes TC, Nitsch RM, Erfurth A, Wurtman RJ. Phospholipid and phospholipid metabolites in rat frontal cortex are decreased following nucleus basalis lesions. Annals of the New York Academy of Sciences. 695: 241-3. PMID 8239290 DOI: 10.1111/j.1749-6632.1993.tb23060.x  0.741
1993 Slack BE, Nitsch RM, Livneh E, Kunz GM, Eldar H, Wurtman RJ. Regulation of amyloid precursor protein release by protein kinase C in Swiss 3T3 fibroblasts. Annals of the New York Academy of Sciences. 695: 128-31. PMID 8239270 DOI: 10.1111/j.1749-6632.1993.tb23040.x  0.676
1993 Nitsch RM, Slack BE, Farber SA, Borghesani PR, Schulz JG, Kim C, Felder CC, Growdon JH, Wurtman RJ. Receptor-coupled amyloid precursor protein processing. Annals of the New York Academy of Sciences. 695: 122-7. PMID 8239269 DOI: 10.1111/J.1749-6632.1993.Tb23039.X  0.78
1993 Kischka U, Farber SA, Marshall D, Wurtman RJ. Carbachol and naloxone synergistically elevate dopamine release in rat striatum: an in vivo microdialysis study. Brain Research. 613: 288-90. PMID 8186978 DOI: 10.1016/0006-8993(93)90912-7  0.593
1993 Lehnert H, Wurtman RJ. Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications. Psychotherapy and Psychosomatics. 60: 18-32. PMID 7901866 DOI: 10.1159/000288676  0.457
1993 Dollins AB, Lynch HJ, Wurtman RJ, Deng MH, Kischka KU, Gleason RE, Lieberman HR. Effect of pharmacological daytime doses of melatonin on human mood and performance. Psychopharmacology. 112: 490-6. PMID 7871062 DOI: 10.1007/BF02244899  0.781
1993 Kaakkola S, Wurtman RJ. Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study. Brain Research Bulletin. 32: 667-72. PMID 7693310 DOI: 10.1016/0361-9230(93)90171-7  0.593
1992 Slack BE, Richardson UI, Nitsch RM, Wurtman RJ. Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. Brain Research. 585: 169-76. PMID 1511298 DOI: 10.1016/0006-8993(92)91203-Q  0.677
1992 Conlay LA, Sabounjian LA, Wurtman RJ. Exercise and neuromodulators: choline and acetylcholine in marathon runners. International Journal of Sports Medicine. 13: S141-2. PMID 1483754 DOI: 10.1055/s-2007-1024619  0.615
1992 Johnson DA, Ulus IH, Wurtman RJ. Caffeine potentiates the enhancement by choline of striatal acetylcholine release. Life Sciences. 51: 1597-601. PMID 1435067 DOI: 10.1016/0024-3205(92)90622-V  0.703
1992 Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science (New York, N.Y.). 258: 304-7. PMID 1411529 DOI: 10.1126/SCIENCE.1411529  0.73
1992 Gardier AM, Kaakkola S, Erfurth A, Wurtman RJ. Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs. Brain Research. 588: 67-74. PMID 1382807 DOI: 10.1016/0006-8993(92)91345-F  0.766
1992 Kaakkola S, Wurtman RJ. Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study. Brain Research. 587: 241-9. PMID 1381981 DOI: 10.1016/0006-8993(92)91003-W  0.593
1992 Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ. Evidence for a membrane defect in Alzheimer disease brain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1671-5. PMID 1311847 DOI: 10.1073/Pnas.89.5.1671  0.728
1992 Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. SECRETION OF ALZHEIMER AMYLOID PRECURSOR PROTEIN IS STIMULATED BY MUSCARINIC RECEPTOR ACTIVATION. Clinical Neuropharmacology. 15: 464B. DOI: 10.1097/00002826-199202001-00902  0.622
1991 Buyukuysal RL, Holmes TC, Wurtman RJ. Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids. Brain Research. 541: 1-6. PMID 2029609 DOI: 10.1016/0006-8993(91)91066-A  0.552
1991 Caballero B, Gleason RE, Wurtman RJ. Plasma amino acid concentrations in healthy elderly men and women. The American Journal of Clinical Nutrition. 53: 1249-52. PMID 2021131 DOI: 10.1093/Ajcn/53.5.1249  0.529
1991 Caballero B, Wurtman RJ. Differential effects of insulin resistance on leucine and glucose kinetics in obesity. Metabolism: Clinical and Experimental. 40: 51-8. PMID 1984571 DOI: 10.1016/0026-0495(91)90192-Y  0.529
1991 Kerstetter J, Caballero B, O'Brien K, Wurtman R, Allen L. Mineral homeostasis in obesity: effects of euglycemic hyperinsulinemia. Metabolism: Clinical and Experimental. 40: 707-13. PMID 1870424 DOI: 10.1016/0026-0495(91)90088-E  0.527
1991 Berry EM, Growdon JH, Wurtman JJ, Caballero B, Wurtman RJ. A balanced carbohydrate: protein diet in the management of Parkinson's disease. Neurology. 41: 1295-7. PMID 1866021 DOI: 10.1212/WNL.41.8.1295  0.631
1991 Farber SA, Buyukuysal RL, Wurtman RJ. Why do phospholipid levels decrease with repeated stimulation? A study of choline-containing compounds in rat striatum following electrical stimulation. Annals of the New York Academy of Sciences. 640: 114-7. PMID 1776728 DOI: 10.1111/j.1749-6632.1991.tb00201.x  0.593
1991 Growdon JH, Nader TM, Schoenfeld J, Wurtman RJ. L-threonine in the treatment of spasticity. Clinical Neuropharmacology. 14: 403-12. PMID 1742749 DOI: 10.1097/00002826-199110000-00003  0.423
1991 Gardier AM, Wurtman RJ. Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration. Brain Research. 540: 325-30. PMID 1711396 DOI: 10.1016/0006-8993(91)90530-9  0.556
1991 Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ. Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 110-3. PMID 1663712 DOI: 10.1111/J.1749-6632.1991.Tb00200.X  0.729
1990 Conlay LA, Maher TJ, Wurtman RJ. Alanine increases blood pressure during hypotension. Pharmacology & Toxicology. 66: 415-6. PMID 2371250 DOI: 10.1111/J.1600-0773.1990.TB00771.X  0.699
1990 Maher TJ, Kiritsy PJ, Moya-Huff FA, Casacci F, De Marchi F, Wurtman RJ. Use of parenteral dipeptides to increase serum tyrosine levels and to enhance catecholamine-mediated neurotransmission. Journal of Pharmaceutical Sciences. 79: 685-7. PMID 2172510 DOI: 10.1002/jps.2600790807  0.498
1990 Holbrook PG, Wurtman RJ. Calcium-dependent incorporation of choline into phosphatidylcholine (PC) by base-exchange in rat brain membranes occurs preferentially with phospholipid substrates containing docosahexaenoic acid (22:6(n-3)). Biochimica Et Biophysica Acta. 1046: 185-8. PMID 2171666 DOI: 10.1016/0005-2760(90)90187-3  0.587
1990 Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Research. 536: 240-4. PMID 2150771 DOI: 10.1016/0006-8993(90)90030-F  0.49
1990 Kreutz MR, Acworth IN, Lehnert H, Wurtman RJ. Systemic administration of thyrotropin-releasing hormone enhances striatal dopamine release in vivo. Brain Research. 536: 347-52. PMID 1707722 DOI: 10.1016/0006-8993(90)90049-H  0.739
1990 Schaechter JD, Wurtman RJ. Serotonin release varies with brain tryptophan levels. Brain Research. 532: 203-10. PMID 1704290 DOI: 10.1016/0006-8993(90)91761-5  0.651
1989 Acworth IN, Ressler K, Wurtman RJ. Feeding-associated alterations in striatal neurotransmitter release. Annals of the New York Academy of Sciences. 575: 596-8. PMID 11538862 DOI: 10.1111/J.1749-6632.1989.TB53307.X  0.697
1989 Slack BE, Liscovitch M, Blusztajn JK, Wurtman RJ. Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine. Journal of Neurochemistry. 53: 472-81. PMID 2746233 DOI: 10.1111/J.1471-4159.1989.Tb07358.X  0.725
1989 Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum. Brain Research. 484: 217-27. PMID 2713682 DOI: 10.1016/0006-8993(89)90364-8  0.784
1989 Conlay LA, Wurtman RJ, Lopez G-Coviella I, Blusztajn JK, Vacanti CA, Logue M, During M, Caballero B, Maher TJ, Evoniuk G. Effects of running the Boston marathon on plasma concentrations of large neutral amino acids. Journal of Neural Transmission. 76: 65-71. PMID 2708978 DOI: 10.1007/BF01244992  0.777
1989 Wurtman JJ, Brzezinski A, Wurtman RJ, Laferrere B. Effect of nutrient intake on premenstrual depression. American Journal of Obstetrics and Gynecology. 161: 1228-34. PMID 2589444 DOI: 10.1016/0002-9378(89)90671-6  0.709
1989 Lehnert H, Beyer J, Reinstein DK, Richardson UI, Wurtman RJ. Relationship between pituitary ACTH content and hypothalamic catecholamines in the rat. Research in Experimental Medicine. Zeitschrift Fã¼R Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie. 189: 289-93. PMID 2554439 DOI: 10.1007/BF01852261  0.457
1989 During MJ, Acworth IN, Wurtman RJ. Dopamine release in rat striatum: physiological coupling to tyrosine supply. Journal of Neurochemistry. 52: 1449-54. PMID 2496199 DOI: 10.1111/j.1471-4159.1989.tb09192.x  0.706
1989 Laferrere B, Wurtman RJ. Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats. Brain Research. 504: 258-63. PMID 2480833 DOI: 10.1016/0006-8993(89)91365-6  0.641
1989 Schaechter JD, Wurtman RJ. Tryptophan availability modulates serotonin release from rat hypothalamic slices. Journal of Neurochemistry. 53: 1925-33. PMID 2478666 DOI: 10.1111/j.1471-4159.1989.tb09263.x  0.651
1989 Schaechter JD, Wurtman RJ. Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release. Life Sciences. 44: 265-71. PMID 2464733 DOI: 10.1016/0024-3205(89)90184-7  0.651
1989 Wurtman RJ, Ulus IH, Blusztajn JK, Lopez-Coviella I, Agut J, Ortiz JA, Logue M, Mauron C, Growdon JH. Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer's disease Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1: 15. DOI: 10.1007/BF02312196  0.775
1988 Conlay LA, Maher TJ, Roberts CH, Wurtman RJ. Effects of hemorrhagic hypotension on tyrosine concentrations in rat spinal cord and plasma. Neurochemistry International. 12: 291-5. PMID 11537399 DOI: 10.1016/0197-0186(88)90167-2  0.694
1988 During MJ, Acworth IN, Wurtman RJ. Effects of systemic L-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens. Brain Research. 452: 378-80. PMID 3401745 DOI: 10.1016/0006-8993(88)90043-1  0.706
1988 Conlay LA, Evoniuk G, Wurtman RJ. Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 85: 4483-5. PMID 3380802 DOI: 10.1073/PNAS.85.12.4483  0.776
1988 Caballero B, Finer N, Wurtman RJ. Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. Metabolism: Clinical and Experimental. 37: 672-6. PMID 3290625 DOI: 10.1016/0026-0495(88)90089-3  0.628
1988 Acworth IN, During MJ, Wurtman RJ. Tyrosine: effects on catecholamine release. Brain Research Bulletin. 21: 473-7. PMID 3214752 DOI: 10.1016/0361-9230(88)90161-X  0.706
1988 During MJ, Acworth IN, Wurtman RJ. Phenylalanine administration influences dopamine release in the rat's corpus striatum. Neuroscience Letters. 93: 91-5. PMID 3211373 DOI: 10.1016/0304-3940(88)90018-3  0.706
1988 Wurtman R, Caballero B, Salzman E. Facilitation of levodopa-induced dyskinesias by dietary carbohydrates. The New England Journal of Medicine. 319: 1288-9. PMID 3185626 DOI: 10.1056/NEJM198811103191915  0.529
1988 Brzezinski A, Lynch HJ, Seibel MM, Deng MH, Nader TM, Wurtman RJ. The circadian rhythm of plasma melatonin during the normal menstrual cycle and in amenorrheic women. The Journal of Clinical Endocrinology and Metabolism. 66: 891-5. PMID 3129448 DOI: 10.1210/jcem-66-5-891  0.517
1988 Holbrook PG, Wurtman RJ. Presence of base-exchange activity in rat brain nerve endings: dependence on soluble substrate concentrations and effect of cations. Journal of Neurochemistry. 50: 156-62. PMID 3121785 DOI: 10.1111/j.1471-4159.1988.tb13243.x  0.587
1988 Kim SH, Wurtman RJ. Selective effects of CGS 10686B, dl-fenfluramine or fluoxetine on nutrient selection. Physiology & Behavior. 42: 319-22. PMID 2838855 DOI: 10.1016/0031-9384(88)90272-7  0.595
1988 BRZEZINSKI A, WURTMAN RJ. The Pineal Gland Obstetrical & Gynecological Survey. 43: 197-207. DOI: 10.1097/00006254-198804000-00003  0.507
1987 Lopez G-Coviella I, Agut J, Von Borstel R, Wurtman RJ. Metabolism of cytidine (5?)-diphosphocholine (cdp-choline) following oral and intravenous administration to the human and the rat. Neurochemistry International. 11: 293-7. PMID 20501174 DOI: 10.1016/0197-0186(87)90049-0  0.591
1987 Brzezinski A, Seibel MM, Lynch HJ, Deng MH, Wurtman RJ. Melatonin in human preovulatory follicular fluid. The Journal of Clinical Endocrinology and Metabolism. 64: 865-7. PMID 3818907 DOI: 10.1210/jcem-64-4-865  0.513
1987 Irie K, Wurtman RJ. Release of norepinephrine from rat hypothalamic slices: effects of desipramine and tyrosine. Brain Research. 423: 391-4. PMID 3676816 DOI: 10.1016/0006-8993(87)90869-9  0.475
1987 Wurtman RJ, Maher TJ. Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note. Journal of Neural Transmission. 70: 169-73. PMID 3668518 DOI: 10.1007/BF01252517  0.443
1987 Liscovitch M, Blusztajn JK, Freese A, Wurtman RJ. Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate. The Biochemical Journal. 241: 81-6. PMID 3566713 DOI: 10.1042/Bj2410081  0.614
1987 Maher TJ, Wurtman RJ. Possible neurologic effects of aspartame, a widely used food additive. Environmental Health Perspectives. 75: 53-7. PMID 3319565 DOI: 10.1289/Ehp.877553  0.5
1987 Lieberman HR, Wurtman RJ, Emde GG, Roberts C, Coviella IL. The effects of low doses of caffeine on human performance and mood. Psychopharmacology. 92: 308-12. PMID 3114783 DOI: 10.1007/BF00210835  0.454
1987 Waldhauser F, Lieberman HR, Lynch HJ, Waldhauser M, Herkner K, Frisch H, Vierhapper H, Waldhäusl W, Schemper M, Wurtman RJ. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. Neuroendocrinology. 46: 125-30. PMID 3114663 DOI: 10.1159/000124808  0.644
1987 Ulus IH, Wurtman RJ. Choline increases acetylcholine release. Lancet. 1: 624. PMID 2881154 DOI: 10.1016/S0140-6736(87)90258-3  0.703
1987 Lehnert H, Lombardi F, Raeder EA, Lorenzo AV, Verrier RL, Lown B, Wurtman RJ. Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat. Journal of Cardiovascular Pharmacology. 10: 389-97. PMID 2444791 DOI: 10.1097/00005344-198710000-00003  0.457
1987 HOLBROOK PG, WURTMAN RJ. A Role for Base Exchange in Cellular Calcium Signaling? Annals of the New York Academy of Sciences. 494: 114-115. DOI: 10.1111/J.1749-6632.1987.TB29496.X  0.587
1987 LIEBERMAN HR, WURTMAN RJ, EMDE GG, G. COVIELLA IL. The Effects of Caffeine and Aspirin on Mood and Performance Journal of Clinical Psychopharmacology. 7: 315???320. DOI: 10.1097/00004714-198710000-00004  0.454
1987 Lopez G.-coviella I, Agut J, Von Borstel R, Wurtman RJ. Metabolism of cytidine (5′)-diphosphocholine (cdp-choline) following oral and intravenous administration to the human and the rat Neurochemistry International. 11: 293-297. DOI: 10.1016/0197-0186(87)90049-0  0.522
1986 Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters. Journal of Neurochemistry. 47: 1936-41. PMID 3772385 DOI: 10.1111/J.1471-4159.1986.Tb13111.X  0.614
1986 Caballero B, Mahon BE, Rohr FJ, Levy HL, Wurtman RJ. Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria. The Journal of Pediatrics. 109: 668-71. PMID 3761084 DOI: 10.1016/S0022-3476(86)80239-6  0.529
1986 Milner JD, Irie K, Wurtman RJ. Effects of phenylalanine on the release of endogenous dopamine from rat striatal slices. Journal of Neurochemistry. 47: 1444-8. PMID 3760870 DOI: 10.1111/j.1471-4159.1986.tb00777.x  0.497
1986 Lopez I, Coviella G, Agut J, Wurtman RJ. Effect of cytidine(5')diphosphocholine (CDP-choline) on the total urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) by rats and humans. Journal of Neural Transmission. 66: 129-34. PMID 3746287 DOI: 10.1007/BF01260908  0.543
1986 Huff FJ, Maire JC, Growdon JH, Corkin S, Wurtman RJ. Cholinesterases in cerebrospinal fluid. Correlations with clinical measures in Alzheimer's disease. Journal of the Neurological Sciences. 72: 121-9. PMID 3711929 DOI: 10.1016/0022-510X(86)90001-8  0.634
1986 Conlay LA, Maher TJ, Godley BF, Wurtman RJ. Spinal cord noradrenergic neurons are activated in hypotension. Brain Research. 375: 210-3. PMID 3087580 DOI: 10.1016/0006-8993(86)90978-9  0.708
1985 Wurtman RJ, Blusztajn JK, Maire JC. "Autocannibalism" of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease-A hypothesis. Neurochemistry International. 7: 369-72. PMID 20492936 DOI: 10.1016/0197-0186(85)90127-5  0.534
1985 Blusztajn JK, Zeisel SH, Wurtman RJ. Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. The Biochemical Journal. 232: 505-11. PMID 4091805 DOI: 10.1042/Bj2320505  0.493
1985 Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. High-performance liquid chromatography of water-soluble choline metabolites. Analytical Biochemistry. 151: 182-7. PMID 4091278 DOI: 10.1016/0003-2697(85)90069-7  0.614
1985 Reinstein DK, Lehnert H, Wurtman RJ. Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats. Life Sciences. 37: 2157-63. PMID 4068899 DOI: 10.1016/0024-3205(85)90566-1  0.457
1985 Milner JD, Wurtman RJ. Tyrosine availability determines stimulus-evoked dopamine release from rat striatal slices. Neuroscience Letters. 59: 215-20. PMID 4058795 DOI: 10.1016/0304-3940(85)90202-2  0.304
1985 Small DH, Wurtman RJ. Association of serotonin, dopamine, or noradrenaline with an actin-like component in pheochromocytoma (PC12) cells. Journal of Neurochemistry. 45: 825-31. PMID 4031865 DOI: 10.1111/j.1471-4159.1985.tb04068.x  0.548
1985 Small DH, Wurtman RJ. Binding of [3H]serotonin to skeletal muscle actin. Journal of Neurochemistry. 45: 819-24. PMID 4031864 DOI: 10.1111/j.1471-4159.1985.tb04067.x  0.548
1985 Tacconi M, Wurtman RJ. Rat brain phosphatidyl-N,N-dimethylethanolamine is rich in polyunsaturated fatty acids. Journal of Neurochemistry. 45: 805-9. PMID 4031862 DOI: 10.1111/j.1471-4159.1985.tb04064.x  0.52
1985 Lieberman HR, Corkin S, Spring BJ, Wurtman RJ, Growdon JH. The effects of dietary neurotransmitter precursors on human behavior. The American Journal of Clinical Nutrition. 42: 366-70. PMID 4025206 DOI: 10.1093/ajcn/42.2.366  0.596
1985 Logue MP, Growdon JH, Coviella IL, Wurtman RJ. Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats. Life Sciences. 37: 403-9. PMID 4021721 DOI: 10.1016/0024-3205(85)90401-1  0.49
1985 Conlay LA, Maher TJ, Wurtman RJ. Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats. Brain Research. 333: 81-4. PMID 3995291 DOI: 10.1016/0006-8993(85)90126-X  0.724
1985 Lieberman HR, Garfield G, Waldhauser F, Lynch HJ, Wurtman RJ. Possible behavioral consequences of light-induced changes in melatonin availability. Annals of the New York Academy of Sciences. 453: 242-52. PMID 3865584 DOI: 10.1111/j.1749-6632.1985.tb11814.x  0.639
1985 Tacconi M, Wurtman RJ. Phosphatidylcholine produced in rat synaptosomes by N-methylation is enriched in polyunsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 82: 4828-31. PMID 3860825 DOI: 10.1073/PNAS.82.14.4828  0.52
1985 Wurtman RJ, Lieberman HR. Melatonin secretion as a mediator of circadian variations in sleep and sleepiness. Journal of Pineal Research. 2: 301-3. PMID 3831313 DOI: 10.1111/J.1600-079X.1985.Tb00647.X  0.454
1985 Wurtman J, Wurtman R, Mark S, Tsay R, Gilbert W, Growdon J. d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects Journal of Clinical Psychopharmacology. 5: 309. DOI: 10.1097/00004714-198510000-00023  0.423
1984 Wurtman RJ, Maher TJ. Strategies for assessing the effects of food additives on the brain and behavior. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: S318-22. PMID 6745550 DOI: 10.1016/0272-0590(84)90258-6  0.48
1984 Reinstein DK, Lehnert H, Scott NA, Wurtman RJ. Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats. Life Sciences. 34: 2225-31. PMID 6727560 DOI: 10.1016/0024-3205(84)90209-1  0.457
1984 von Borstel RW, Renshaw AA, Wurtman RJ. Adenosine strongly potentiates pressor responses to nicotine in rats. Proceedings of the National Academy of Sciences of the United States of America. 81: 5599-603. PMID 6591207 DOI: 10.1073/PNAS.81.17.5599  0.569
1984 Small DH, Wurtman RJ. Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes. Proceedings of the National Academy of Sciences of the United States of America. 81: 959-63. PMID 6583691 DOI: 10.1073/PNAS.81.3.959  0.548
1984 Maire JC, Wurtman RJ. Choline production from choline-containing phospholipids: a hypothetical role in Alzheimer's disease and aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8: 637-42. PMID 6543397 DOI: 10.1016/0278-5846(84)90027-7  0.534
1984 Agut J, Coviella IL, Wurtman RJ. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. 23: 1403-6. PMID 6543245 DOI: 10.1016/0028-3908(84)90080-7  0.303
1984 Maher TJ, Glaeser BS, Wurtman RJ. Diurnal variations in plasma concentrations of basic and neutral amino acids and in red cell concentrations of aspartate and glutamate: effects of dietary protein intake. The American Journal of Clinical Nutrition. 39: 722-9. PMID 6538743 DOI: 10.1093/Ajcn/39.5.722  0.496
1984 Lieberman HR, Waldhauser F, Garfield G, Lynch HJ, Wurtman RJ. Effects of melatonin on human mood and performance. Brain Research. 323: 201-7. PMID 6525511 DOI: 10.1016/0006-8993(84)90290-7  0.641
1984 Waldhauser F, Waldhauser M, Lieberman HR, Deng MH, Lynch HJ, Wurtman RJ. Bioavailability of oral melatonin in humans. Neuroendocrinology. 39: 307-13. PMID 6493445 DOI: 10.1159/000123997  0.642
1984 Conlay LA, Maher TJ, Wurtman RJ. Tyrosine's pressor effect in hypotensive rats is not mediated by tyramine. Life Sciences. 35: 1207-12. PMID 6472051 DOI: 10.1016/0024-3205(84)90192-9  0.721
1984 Spindel ER, Wurtman RJ, McCall A, Carr DB, Conlay L, Griffith L, Arnold MA. Neuroendocrine effects of caffeine in normal subjects. Clinical Pharmacology and Therapeutics. 36: 402-7. PMID 6467801 DOI: 10.1038/Clpt.1984.195  0.782
1984 Lehnert H, Reinstein DK, Strowbridge BW, Wurtman RJ. Neurochemical and behavioral consequences of acute, uncontrollable stress: effects of dietary tyrosine. Brain Research. 303: 215-23. PMID 6204715 DOI: 10.1016/0006-8993(84)91207-1  0.704
1984 Yokogoshi H, Roberts CH, Caballero B, Wurtman RJ. Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles. The American Journal of Clinical Nutrition. 40: 1-7. PMID 6204522 DOI: 10.1093/AJCN/40.1.1  0.529
1984 Tacconi MT, Wurtman RJ. Physiological disposition of oral piracetam in Sprague-Dawley rats. The Journal of Pharmacy and Pharmacology. 36: 659-62. PMID 6150081 DOI: 10.1111/j.2042-7158.1984.tb04838.x  0.52
1984 Waldhauser F, Weiszenbacher G, Frisch H, Zeitlhuber U, Waldhauser M, Wurtman RJ. Fall in nocturnal serum melatonin during prepuberty and pubescence. Lancet. 1: 362-5. PMID 6141425 DOI: 10.1016/S0140-6736(84)90412-4  0.556
1984 Waldhauser F, Lieberman HJ, Frisch H, Herckner K, Crowley WF, Wurtman RJ. Melatonin does not alter human serum gondotropin and testosterone levels, but it increases prolactin levels Pediatric Research. 18: 1228-1228. DOI: 10.1203/00006450-198411000-00166  0.521
1983 von Borstel RW, Wurtman RJ, Conlay LA. Chronic caffeine consumption potentiates the hypotensive action of circulating adenosine. Life Sciences. 32: 1151-8. PMID 6827895 DOI: 10.1016/0024-3205(83)90121-2  0.733
1983 Conlay LA, Maher TJ, Moses PL, Wurtman RJ. Tyrosine's vasoactive effect in the dog shock model depends on the animal's starting blood pressure. Journal of Neural Transmission. 58: 69-74. PMID 6655468 DOI: 10.1007/BF01249125  0.707
1983 Heraief E, Burckhardt P, Mauron C, Wurtman JJ, Wurtman RJ. The treatment of obesity by carbohydrate deprivation suppresses plasma tryptophan and its ratio to other large neutral amino acids. Journal of Neural Transmission. 57: 187-95. PMID 6644285 DOI: 10.1007/BF01245117  0.704
1983 Glaeser BS, Maher TJ, Wurtman RJ. Changes in brain levels of acidic, basic, and neutral amino acids after consumption of single meals containing various proportions of protein. Journal of Neurochemistry. 41: 1016-21. PMID 6619840 DOI: 10.1111/j.1471-4159.1983.tb09045.x  0.499
1983 Gibson CJ, Watkins CJ, Wurtman RJ. Tyrosine administration enhances dopamine synthesis and release in light-activated rat retina. Journal of Neural Transmission. 56: 153-60. PMID 6134783 DOI: 10.1007/BF01243274  0.595
1983 Askanazi J, Weissman C, Conlay L, Wurtman RJ, Milic-Emili J, Kinney JM. L-TRYPTOPHAN IN THE CONTROL OF RESPIRATION Critical Care Medicine. 11: 221. DOI: 10.1097/00003246-198303000-00039  0.645
1983 Waldhauser F, Wurtman RJ. CHAPTER 6 – The Secretion and Actions of Melatonin Biochemical Actions of Hormones. 187-225. DOI: 10.1016/B978-0-12-452810-9.50011-5  0.556
1982 McCall AL, Millington WR, Wurtman RJ. Blood-brain barrier transport of caffeine: dose-related restriction of adenine transport. Life Sciences. 31: 2709-15. PMID 7154859 DOI: 10.1016/0024-3205(82)90715-9  0.586
1982 Millington WR, Wurtman RJ. Choline and physostigmine enhance haloperidol-induced HVA and DOPAC accumulation. European Journal of Pharmacology. 80: 431-4. PMID 7106193 DOI: 10.1016/0014-2999(82)90091-7  0.586
1982 Millington WR, Wurtman RJ. Choline administration elevates brain phosphorylcholine concentrations. Journal of Neurochemistry. 38: 1748-52. PMID 7077335 DOI: 10.1111/j.1471-4159.1982.tb06658.x  0.586
1982 Gelenberg AJ, Wojcik JD, Gibson CJ, Wurtman RJ. Tyrosine for depression. Journal of Psychiatric Research. 17: 175-80. PMID 6764934 DOI: 10.1016/0022-3956(82)90019-X  0.477
1982 Lieberman HR, Corkin S, Spring BJ, Growdon JH, Wurtman RJ. Mood, performance, and pain sensitivity: changes induced by food constituents. Journal of Psychiatric Research. 17: 135-45. PMID 6764930 DOI: 10.1016/0022-3956(82)90015-2  0.586
1982 McCall AL, Millington WR, Wurtman RJ. Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. 79: 5406-10. PMID 6752947 DOI: 10.1073/PNAS.79.17.5406  0.586
1982 Pan RM, Mauron C, Glaeser B, Wurtman RJ. Effect of various oral glucose doses on plasma neutral amino acid levels. Metabolism: Clinical and Experimental. 31: 937-43. PMID 6750316 DOI: 10.1016/0026-0495(82)90185-8  0.722
1982 Growdon JH, Melamed E, Logue M, Hefti F, Wurtman RJ. Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. Life Sciences. 30: 827-32. PMID 6175872 DOI: 10.1016/0024-3205(82)90596-3  0.678
1982 Reinstein D, Corkin S, Growdon JH, Wurtman RJ, Zeisel SH. The second meeting of the international study group on the pharmacology of memory disorders associated with aging (ISG) Neuropsychologia. 20: 225-226. DOI: 10.1016/0028-3932(82)90015-X  0.598
1982 Mauron C, Wurtman RJ. Co-administering tyrosine with glucose potentiates its effect on brain tyrosine levels Journal of Neural Transmission. 55: 317-321. DOI: 10.1007/BF01243453  0.704
1981 Zeisel S, Reinstein D, Corkin S, Growdon J, Wurtman R. Cholinergic neurones and memory. Nature. 293: 187-8. PMID 7278975 DOI: 10.1038/293187a0  0.599
1981 Chiel HJ, Wurtman RJ. Short-term variations in diet composition change the pattern of spontaneous motor activity in rats. Science (New York, N.Y.). 213: 676-8. PMID 7256271 DOI: 10.1126/SCIENCE.7256271  0.564
1981 Conlay LA, Maher TJ, Wurtman RJ. Tyrosine increases blood pressure in hypotensive rats. Science (New York, N.Y.). 212: 559-60. PMID 7209553 DOI: 10.1126/Science.7209553  0.717
1981 Melamed E, Hefti F, Pettibone DJ, Liebman J, Wurtman RJ. Aromatic L-amino acid decarboxylase in rat corpus striatum: implications for action of L-dopa in parkinsonism. Neurology. 31: 651-5. PMID 7195482 DOI: 10.1212/WNL.31.6.651  0.771
1981 Magil SG, Zeisel SH, Wurtman RJ. Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine. The Journal of Nutrition. 111: 166-70. PMID 7192727 DOI: 10.1093/Jn/111.1.166  0.493
1981 Agharanya JC, Alonso R, Wurtman RJ. Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects. The American Journal of Clinical Nutrition. 34: 82-7. PMID 7192489 DOI: 10.1093/AJCN/34.1.82  0.472
1981 Zeisel SH, Wurtman RJ. Developmental changes in rat blood choline concentration. The Biochemical Journal. 198: 565-70. PMID 7034731 DOI: 10.1042/BJ1980565  0.493
1981 Spindel ER, Pettibone DJ, Wurtman RJ. Thyrotropin-releasing hormone (TRH) content of rat striatum: modification by drugs and lesions. Brain Research. 216: 323-31. PMID 6265032 DOI: 10.1016/0006-8993(81)90134-7  0.761
1981 Zeisel SH, Mauron C, Watkins CJ, Wurtman RJ. Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat. Brain Research. 227: 551-64. PMID 6167336 DOI: 10.1016/0165-3806(81)90008-0  0.776
1981 Spindel E, Pettibone D, Fisher L, Fernstrom J, Wurtman R. Characterization of neuropeptides by reversed-phase, ion-pair liquid chromatography with post-column detection by radioimmunoassay. Application to thyrotropin-releasing hormone, substance P, and vasopressin. Journal of Chromatography. 222: 381-7. PMID 6164686 DOI: 10.1016/S0378-4347(00)84138-9  0.776
1981 Hefti F, Melamed E, Bhawan J, Wurtman RJ. Long-term administration of L-DOPA does not damage dopaminergic neurons in the mouse Neurology. 31: 1194-1194. DOI: 10.1212/WNL.31.9.1194  0.602
1981 Wurtman JJ, Wurtman RJ, Growdon JH, Henry P, Lipscomb A, Zeisel SH. Carbohydrate craving in obese people: Suppression by treatments affecting serotoninergic transmission International Journal of Eating Disorders. 1: 2-15. DOI: 10.1002/1098-108X(198123)1:1<2::AID-EAT2260010102>3.0.CO;2-Q  0.49
1981 Wurtman RJ, Growdon JH, Corkin S, Reinstein D, Zeisel S. Meeting report Neurobiology of Aging. 2: 149-151.  0.404
1980 Morre MC, Hefti F, Wurtman RJ. Regional tyrosine levels in rat brain after tyrosine administration. Journal of Neural Transmission. 49: 45-50. PMID 7441238 DOI: 10.1007/BF01249188  0.495
1980 Alonso R, Agharanya JC, Wurtman RJ. Tyrosine loading enhances catecholamine excretion by rats. Journal of Neural Transmission. 49: 31-43. PMID 7441237 DOI: 10.1007/BF01249187  0.472
1980 Mauron C, Wurtman JJ, Wurtman RJ. Clonidine increases food and protein consumption in rats. Life Sciences. 27: 781-91. PMID 7412504 DOI: 10.1016/0024-3205(80)90332-X  0.722
1980 Melamed E, Hefti F, Wurtman RJ. Decarboxylation of exogenous L-DOPA in rat striatum after lesions of the dopaminergic nigrostriatal neurons: the role of striatal capillaries. Brain Research. 198: 244-8. PMID 7407592 DOI: 10.1016/0006-8993(80)90363-7  0.602
1980 Zeisel SH, Epstein MF, Wurtman RJ. Elevated choline concentration in neonatal plasma. Life Sciences. 26: 1827-31. PMID 7392816 DOI: 10.1016/0024-3205(80)90585-8  0.493
1980 Melamed E, Hefti F, Wurtman RJ. Diminished decarboxylation of L-DOPA in rat striatum after intrastriatal injections of kainic acid. Neuropharmacology. 19: 409-11. PMID 7383284 DOI: 10.1016/0028-3908(80)90194-X  0.602
1980 Melamed E, Hefti F, Wurtman RJ. L-3,4-Dihydroxyphenylalanine and L-5-hydroxytryptophan decarboxylase activities in rat striatum: effect of selective destruction of dopaminergic or serotoninergic input. Journal of Neurochemistry. 34: 1753-6. PMID 7381499 DOI: 10.1111/j.1471-4159.1980.tb11270.x  0.602
1980 Gelenberg AJ, Wojcik JD, Growdon JH, Sved AF, Wurtman RJ. Tyrosine for the treatment of depression. The American Journal of Psychiatry. 137: 622-3. PMID 7369415 DOI: 10.1176/AJP.137.5.622  0.613
1980 Zeisel SH, Growdon JH, Wurtman RJ, Magil SG, Logue M. Normal plasma choline responses to ingested lecithin. Neurology. 30: 1226-9. PMID 7191517 DOI: 10.1212/WNL.30.11.1226  0.61
1980 Melamed E, Glaeser B, Growdon JH, Wurtman RJ. Plasma tyrosine in normal humans: effects of oral tyrosine and protein-containing meals. Journal of Neural Transmission. 47: 299-306. PMID 7190187 DOI: 10.1007/BF01247323  0.6
1980 Hefti F, Melamed E, Sahakian BJ, Wurtman RJ. Circling behavior in rats with partial, unilateral nigro-striatal lesions: effect of amphetamine, apomorphine, and DOPA. Pharmacology, Biochemistry, and Behavior. 12: 185-8. PMID 7189592 DOI: 10.1016/0091-3057(80)90353-6  0.666
1980 Zeisel SH, Story DL, Wurtman RJ, Brunengraber H. Uptake of free choline by isolated perfused rat liver. Proceedings of the National Academy of Sciences of the United States of America. 77: 4417-9. PMID 6933493 DOI: 10.1073/pnas.77.8.4417  0.5
1980 Hefti F, Melamed E, Wurtman RJ. The decarboxylation of DOPA in the parkinsonian brain: in vivo studies on an animal model. Journal of Neural Transmission. Supplementum. 95-101. PMID 6776238 DOI: 10.1007/978-3-7091-8582-7_10  0.602
1980 Spindel E, Wurtman RJ. TRH immunoreactivity in rat brain regions, spinal cord and pancreas: validation by high-pressure liquid chromatography and thin-layer chromatography. Brain Research. 201: 279-88. PMID 6774800 DOI: 10.1016/0006-8993(80)91036-7  0.572
1980 Maher TJ, Wurtman RJ. L-Threonine administration increases glycine concentrations in the rat central nervous system. Life Sciences. 26: 1283-6. PMID 6770208 DOI: 10.1016/0024-3205(80)90086-7  0.496
1980 Spindel ER, Wurtman RJ, Bird ED. Increased TRH content of the basal ganglia in Huntington's disease. The New England Journal of Medicine. 303: 1235-6. PMID 6448349 DOI: 10.1056/NEJM198011203032113  0.572
1980 Melamed E, Hefti F, Wurtman RJ. Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism. Annals of Neurology. 8: 558-63. PMID 6260009 DOI: 10.1002/ana.410080603  0.602
1980 Melamed E, Hefti F, Wurtman RJ. Tyrosine administration increases striatal dopamine release in rats with partial nigrostriatal lesions. Proceedings of the National Academy of Sciences of the United States of America. 77: 4305-9. PMID 6254020 DOI: 10.1073/PNAS.77.7.4305  0.602
1980 Pettibone DJ, Wurtman RJ, Leeman SE. Striatal substance P-like immunoreactivity: characterization of high-performance liquid chromatography and aspects of subcellular distribution and in vitro release by potassium. Life Sciences. 27: 1593-602. PMID 6160368 DOI: 10.1016/0024-3205(80)90569-X  0.692
1980 Pettibone DJ, Wurtman RJ. D-Amphetamine reduces striatal substance P concentrations by presynaptic release of dopamine. Brain Research. 186: 409-19. PMID 6153555 DOI: 10.1016/0006-8993(80)90985-3  0.692
1980 Hefti F, Melamed E, Wurtman RJ. Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization. Brain Research. 195: 123-37. PMID 6105003 DOI: 10.1016/0006-8993(80)90871-9  0.602
1980 Melamed E, Hefti F, Liebman J, Schlosberg AJ, Wurtman RJ. Serotonergic neurones are not involved in action of L-dopa in Parkinson's disease. Nature. 283: 772-4. PMID 6101905 DOI: 10.1038/283772A0  0.602
1979 Millington WR, McCall AL, Wurtman RJ. Lithium and brain choline levels. The New England Journal of Medicine. 300: 196-7. PMID 759848 DOI: 10.1056/NEJM197901253000412  0.544
1979 Fernstrom JD, Wurtman RJ, Hammarstrom-Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein. The American Journal of Clinical Nutrition. 32: 1923-33. PMID 573062 DOI: 10.1093/Ajcn/32.9.1923  0.543
1979 Fernstrom JD, Wurtman RJ, Hammarstrom-Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake. The American Journal of Clinical Nutrition. 32: 1912-22. PMID 573061 DOI: 10.1093/Ajcn/32.9.1912  0.543
1979 Sahakian BJ, Wurtman RJ, Barr JK, Millington WR, Chiel HJ. Low tryptophan diet decreases brain serotonin and alters response to apomorphine. Nature. 279: 731-2. PMID 571966 DOI: 10.1038/279731a0  0.737
1979 Sved AF, Fernstrom JD, Wurtman RJ. Tyrosine administration decreases serum prolactin levels in chronically reserpinized rats. Life Sciences. 25: 1293-9. PMID 513960 DOI: 10.1016/0024-3205(79)90394-1  0.643
1979 Blusztajn JK, Zeisel SH, Wurtman RJ. Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain. Brain Research. 179: 319-27. PMID 509240 DOI: 10.1016/0006-8993(79)90447-5  0.493
1979 Ozaki Y, Wurtman RJ. Spectral power distribution of light sources affects growth and development of rats. Photochemistry and Photobiology. 29: 339-41. PMID 482382 DOI: 10.1111/j.1751-1097.1979.tb07056.x  0.465
1979 Glaeser BS, Melamed E, Growdon JH, Wurtman RJ. Elevation of plasma tyrosine after a single oral dose of L-tyrosine. Life Sciences. 25: 265-71. PMID 481129 DOI: 10.1016/0024-3205(79)90294-7  0.6
1979 Watkins CJ, Wiggins JF, Wurtman RJ. Carbidopa elevates hypothalamic dopa and serum prolactin in rats. Life Sciences. 24: 1675-82. PMID 481101 DOI: 10.1016/0024-3205(79)90252-2  0.485
1979 Fernstrom MH, Wurtman RJ. Increase in striatal choline acetyltransferase activity after choline administration. Brain Research. 165: 358-61. PMID 421145 DOI: 10.1016/0006-8993(79)90570-5  0.585
1979 Sved AF, Fernstrom JD, Wurtman RJ. Tyrosine administration reduces blood pressure and enhances brain norepinephrine release in spontaneously hypertensive rats. Proceedings of the National Academy of Sciences of the United States of America. 76: 3511-4. PMID 291018 DOI: 10.1073/PNAS.76.7.3511  0.643
1979 Spindel E, Wurtman RJ. Reversed-phase, ion-pair separation of thyrotropin-releasing hormone and some analogs. Journal of Chromatography. 175: 198-201. PMID 121124 DOI: 10.1016/S0021-9673(00)86418-3  0.526
1979 Ulus IH, Wurtman RJ. Selective response of rat peripheral sympathetic nervous system to various stimuli. The Journal of Physiology. 293: 513-23. PMID 41093 DOI: 10.1113/Jphysiol.1979.Sp012904  0.703
1979 Growdon JH, Wurtman RJ. Dietary influences on the synthesis of neurotransmitters in the brain. Nutrition Reviews. 37: 129-36. PMID 40170 DOI: 10.1111/J.1753-4887.1979.TB06649.X  0.423
1978 Scally MC, Ulus IH, Wurtman RJ. Choline administration to the rat increases urinary catecholamines. Journal of Neural Transmission. 43: 103-12. PMID 731231 DOI: 10.1007/BF01579069  0.703
1978 Millington WR, McCall AL, Wurtman RJ. Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline. Annals of Neurology. 4: 302-6. PMID 727735 DOI: 10.1002/ana.410040403  0.586
1978 Lynch HJ, Jimerson DC, Ozaki Y, Post RM, Bunney WE, Wurtman RJ. Entrainment of rhythmic melatonin secretion in man to a 12-hour phase shift in the light/dark cycle. Life Sciences. 23: 1557-63. PMID 723434 DOI: 10.1016/0024-3205(78)90583-0  0.48
1978 Hirsch MJ, Wurtman RJ. Lecithin consumption increases acetylcholine concentrations in rat brain and adrenal gland Science. 202: 223-225. PMID 694529 DOI: 10.1126/SCIENCE.694529  0.302
1978 Hirsch MJ, Growdon JH, Wurtman RJ. Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices. Metabolism: Clinical and Experimental. 27: 953-60. PMID 672614 DOI: 10.1016/0026-0495(78)90139-7  0.514
1978 Gibson CJ, Wurtman RJ. Physiological control of brain norepinephrine synthesis by brain tyrosine concentration. Life Sciences. 22: 1399-405. PMID 672404 DOI: 10.1016/0024-3205(78)90633-1  0.473
1978 Roel LE, Moskowitz MA, Rubin D, Markovitz D, Lytle LD, Munro HN, Wurtman RJ. In vivo inhibition of rat brain protein synthesis by d-amphetamine. Journal of Neurochemistry. 31: 341-5. PMID 671028 DOI: 10.1111/J.1471-4159.1978.Tb12467.X  0.786
1978 Airoldi L, Watkins CJ, Wiggins JF, Wurtman RJ. Effect of pyridoxine on the depletion of tissue pyridoxal phosphate by carbidopa. Metabolism: Clinical and Experimental. 27: 771-9. PMID 661563 DOI: 10.1016/0026-0495(78)90211-1  0.632
1978 Pettibone DJ, Wurtman RJ, Leeman SE. D-amphetamine administration reduces substance P concentration in the rat striatum. Biochemical Pharmacology. 27: 839-12. PMID 656130 DOI: 10.1016/0006-2952(78)90541-5  0.692
1978 Scriabine A, Ludden CT, Sweet CS, Porter CC, Ulm EH, Stone CA, Watkins CJ, Wurtman RJ, Cronin BL. Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa. Clinical Science and Molecular Medicine. Supplement. 4: 255s-257s. PMID 282064 DOI: 10.1042/CS055255S  0.485
1978 Ozaki Y, Wurtman RJ, Alonso R, Lynch HJ. Melatonin secretion decreases during the proestrous stage of the rat estrous cycle. Proceedings of the National Academy of Sciences of the United States of America. 75: 531-4. PMID 272672 DOI: 10.1073/PNAS.75.1.531  0.598
1978 Wurtman RJ, Growdon JH. Dietary enhancement of CNS neurotransmitters. Hospital Practice. 13: 71-7. PMID 147851 DOI: 10.1080/21548331.1978.11707296  0.49
1978 Scally MC, Ulus IH, Wurtman RJ, Pettibone DJ. Regional distribution of neurotransmitter-synthesizing enzymes and substance P within the rat corpus striatum. Brain Research. 143: 556-60. PMID 25694 DOI: 10.1016/0006-8993(78)90367-0  0.775
1977 Growdon JH, Hirsch MJ, Wurtman RJ, Wiener W. Oral choline administration to patients with tardive dyskinesia. The New England Journal of Medicine. 297: 524-7. PMID 887103 DOI: 10.1056/NEJM197709082971002  0.507
1977 Nomura M, Colmenares JL, Wurtman RJ. Effect of dietary protein on urinary 5-hydroxyindoleacetic acid levels. Journal of Neurochemistry. 29: 267-71. PMID 886333 DOI: 10.1111/j.1471-4159.1977.tb09618.x  0.453
1977 Hirsch MJ, Growdon JH, Wurtman RJ. Increase in hippocampal acetylcholine after choline administration. Brain Research. 125: 383-5. PMID 851886 DOI: 10.1016/0006-8993(77)90634-5  0.5
1977 Liebschutz J, Airoldi L, Brownstein MJ, Chinn NG, Wurtman RJ. Regional distribution of endogenous and parenteral glutamate, aspartate and glutamine in rat brain. Biochemical Pharmacology. 26: 443-6. PMID 849337 DOI: 10.1016/0006-2952(77)90206-4  0.533
1977 Fernstrom JD, Munro HN, Wurtman RJ. Brain tryptophan in rats on a high fat diet. Nature. 265: 277. PMID 834277 DOI: 10.1038/265277A0  0.534
1977 Wurtman RJ, Watkins CJ. Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase. Nature. 265: 79-80. PMID 834247 DOI: 10.1038/265079a0  0.485
1977 Reinhard JF, Wurtman RJ. Relation between brain 5-HIAA levels and the release of serotonin into brain synapses. Life Sciences. 21: 1741-6. PMID 604702 DOI: 10.1016/0024-3205(77)90153-9  0.512
1977 Lavyne MH, Koltun WA, Clement JA, Rosene DL, Pickren KS, Zervas NT, Wurtman RJ. Decrease in neostriatal blood flow after D-amphetamine administration or electrical stimulation of the substantia nigra. Brain Research. 135: 77-86. PMID 410481 DOI: 10.1016/0006-8993(77)91053-8  0.648
1977 Growdon JH, Cohen EL, Wurtman RJ. Huntington's disease: clinical and chemical effects of choline administration. Annals of Neurology. 1: 418-22. PMID 152596 DOI: 10.1002/ana.410010503  0.49
1977 Growdon JH, Cohen EL, Wurtman RJ. Effects of oral choline administration on serum and CSF choline levels in patients with Huntington's disease. Journal of Neurochemistry. 28: 229-31. PMID 137960 DOI: 10.1111/j.1471-4159.1977.tb07732.x  0.49
1977 Wurtman RJ, Hirsch MJ, Growdon JH. Lecithin consumption raises serum-free-choline levels. Lancet (London, England). 2: 68-9. PMID 69151 DOI: 10.1016/S0140-6736(77)90067-8  0.518
1977 Ulus IH, Meyer E, Wurtman RJ, Lytle LD. Trans-synaptic induction of adrenal tyrosine hydroxylase following amphetamine treatment in the rat. Neuropharmacology. 16: 635-7. PMID 21360 DOI: 10.1016/0028-3908(77)90035-1  0.783
1977 Scally MC, Ulus I, Wurtman RJ. Brain tyrosine level controls striatal dopamine synthesis in haloperidol-treated rats. Journal of Neural Transmission. 41: 1-6. PMID 21228 DOI: 10.1007/BF01252960  0.703
1977 Gibson CJ, Wurtman RJ. Physiological control of brain catechol synthesis by brain tyrosine concentration. Biochemical Pharmacology. 26: 1137-42. PMID 19023 DOI: 10.1016/0006-2952(77)90057-0  0.473
1977 Ulus IH, Scally MC, Wurtman RJ. Choline potentiates the trans-synaptic induction of adrenal tyrosine hydroxylase by reserpine, probably by enhancing the release of acetylcholine. Life Sciences. 21: 145-8. PMID 18644 DOI: 10.1016/0024-3205(77)90435-0  0.703
1977 Ulus IH, Hirsch MJ, Wurtman RJ. Trans-synaptic induction of adrenomedullary tyrosine hydroxylase activity by choline: evidence that choline administration can increase cholinergic transmission. Proceedings of the National Academy of Sciences of the United States of America. 74: 798-800. PMID 15250 DOI: 10.1073/pnas.74.2.798  0.721
1977 Growdon JH, Cohen EL, Wurtman RJ. Treatment of brain disease with dietary precursors of neurotransmitters. Annals of Internal Medicine. 86: 337-9. PMID 14577 DOI: 10.7326/0003-4819-86-3-337  0.49
1976 Ozaki Y, Lynch HJ, Wurtman RJ. Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine. Endocrinology. 98: 1418-24. PMID 1084276 DOI: 10.1210/endo-98-6-1418  0.488
1976 Scriabine A, Ludden CT, Stone CA, Wurtman RJ, Watkins CJ. Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats. Clinical Science and Molecular Medicine. Supplement. 3: 407s-410s. PMID 1071655 DOI: 10.1042/cs051407s  0.485
1976 Minneman KP, Wurtman RJ. The pharmacology of the pineal gland. Annual Review of Pharmacology and Toxicology. 16: 33-51. PMID 180879 DOI: 10.1146/  0.553
1976 Ulus IH, Wurtman RJ. Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. Science (New York, N.Y.). 194: 1060-1. PMID 10629 DOI: 10.1126/science.10629  0.703
1976 Wurtman RJ, Fernstrom JD. Control of brain neurotransmitter synthesis by precursor availability and nutritional state. Biochemical Pharmacology. 25: 1691-6. PMID 8049 DOI: 10.1016/0006-2952(76)90400-7  0.526
1975 Lynch HJ, Ozaki Y, Shakal D, Wurtman RJ. Melatonin excretion of man and rats: effect of time of day, sleep, pinealectomy and food consumption. International Journal of Biometeorology. 19: 267-79. PMID 1241860 DOI: 10.1007/BF01451037  0.398
1975 Moskowitz MA, Meyer E, Wurtman RJ, Lavyne MH, Zervas T. Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infarction in gerbils. Life Sciences. 17: 597-602. PMID 1186426 DOI: 10.1016/S0022-3476(75)80816-X  0.648
1975 Lavyne MH, Moskowitz MA, Larin F, Zervas NT, Wurtman RJ. Brain H-3-catecholamine metabolism in experimental cerebral ischemia. Neurology. 25: 483-5. PMID 1169707 DOI: 10.1212/Wnl.25.5.483  0.659
1975 Yehuda S, Wurtman RJ. Dopaminergic neurons in the nigro-striatal and mesolimbic pathways: mediation of specific effects of D-amphetamine. European Journal of Pharmacology. 30: 154-8. PMID 1168575 DOI: 10.1016/0014-2999(75)90094-1  0.565
1975 Lavyne M, Moskowitz M, Zervas N, Wurtman R. Rotational behavior in gerbils following unilateral common carotid artery ligation. Journal of Neural Transmission. 36: 83-9. PMID 1151370 DOI: 10.1007/Bf01256756  0.653
1975 Minneman KP, Wurtman RJ. Effects of pineal compounds on mammals. Life Sciences. 17: 1189-99. PMID 1105043 DOI: 10.1016/0024-3205(75)90127-7  0.553
1975 Wurtman RJ, Fernstrom JD. Control of brain monoamine synthesis by diet and plasma amino acids. The American Journal of Clinical Nutrition. 28: 638-47. PMID 1093382 DOI: 10.1093/ajcn/28.6.638  0.526
1975 Colmenares JL, Wurtman RJ, Fernstrom JD. Effects of ingestion of a carbohydrate-fat meal on the levels and synthesis of 5-hydroxyindoles in various regions of the rat central nervous system. Journal of Neurochemistry. 25: 825-9. PMID 1082010 DOI: 10.1111/j.1471-4159.1975.tb04413.x  0.526
1975 Jacoby JH, Mueller G, Wurtman RJ. Thyroid state and brain monoamine metabolism. Endocrinology. 97: 1332-5. PMID 1081048 DOI: 10.1210/endo-97-5-1332  0.587
1975 Weiss BF, Liebschutz JL, Wurtman RJ, Munro HN. Participation of dopamine- and serotonin- receptors in the disaggregation of brain polysomes by L-dopa and L-5-HTP. Journal of Neurochemistry. 24: 1191-5. PMID 1079238 DOI: 10.1111/J.1471-4159.1975.Tb03897.X  0.305
1975 Cardinali DP, Wurtman RJ. Methods for assessing the bioligical activity of the mammalian pineal organ. Methods in Enzymology. 39: 376-97. PMID 168469 DOI: 10.1016/S0076-6879(75)39035-6  0.458
1975 Munro HN, Fernstrom JD, Wurtman RJ. Letter: Plasma neutral aminoacids and tryptophan in cirrhosis. Lancet. 2: 419. PMID 51234 DOI: 10.1016/S0140-6736(75)92945-1  0.522
1975 Munro HN, Fernstrom JD, Wurtman RJ. Insulin, plasma aminoacid imbalance, and hepatic coma. Lancet. 1: 722-4. PMID 47485 DOI: 10.1016/S0140-6736(75)91632-3  0.526
1975 Lavyne M, Wurtman RJ, Moskowitz M, Zervas N. Brain catecholamines and cerebral blood flow Life Sciences. 16: 475-486. DOI: 10.1016/S0024-3205(75)80017-8  0.646
1975 Moskowitz MA, Meyer E, Wurtman RJ, Lavyne MH, Zervas NT. Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infraction in gerbils Life Sciences. 17: 597-602. DOI: 10.1016/0024-3205(75)90096-X  0.619
1974 Wurtman RJ, Fernstrom JD. Effects of the Diet on Brain Neurotransmitters. Nutrition Reviews. 32: 193-200. PMID 31253006 DOI: 10.1111/j.1753-4887.1974.tb00958.x  0.526
1974 Roel LE, Schwartz SA, Weiss BF, Munro HN, Wurtman RJ. In vivo inhibition of rat brain protein synthesis by L-dopa. Journal of Neurochemistry. 23: 233-9. PMID 4852386 DOI: 10.1111/J.1471-4159.1974.Tb06939.X  0.301
1974 Minneman KP, Lynch H, Wurtman RJ. Relationship between environmental light intensity and retina-mediated suppression of rat pineal serotonin-N-acetyl-transferase. Life Sciences. 15: 1791-6. PMID 4620990 DOI: 10.1016/0024-3205(74)90180-5  0.553
1974 Madras BK, Cohen EL, Messing R, Munro HN, Wurtman RJ. Relevance of free tryptophan in serum to tissue tryptophan concentrations. Metabolism: Clinical and Experimental. 23: 1107-16. PMID 4427559 DOI: 10.1016/0026-0495(74)90027-4  0.661
1974 Hoeldtke R, Rogawski M, Wurtman RJ. Effect of selective destruction of central and peripheral catecholamine containing neurones with 6 hydroxydopamine on catecholamine excretion in the rat Brit.J.Pharmacol.. 50: 265-270. PMID 4425765 DOI: 10.1111/j.1476-5381.1974.tb08571.x  0.479
1974 Hurko O, Elster P, Wurtman RJ. Adenylate cyclase activity in bovine adrenal medulla. Endocrinology. 94: 591-3. PMID 4359134 DOI: 10.1210/endo-94-2-591  0.615
1974 Wurtman RJ, Larin F, Mostafapour S, Fernstrom JD. Brain catechol synthesis: control by train tyrosine concentration. Science (New York, N.Y.). 185: 183-4. PMID 4276197 DOI: 10.1126/science.185.4146.183  0.526
1974 Zervas NT, Hori H, Negora M, Wurtman RJ, Larin F, Lavyne MH. Reduction in brain dopamine following experimental cerebral ischaemia. Nature. 247: 283-4. PMID 4206475 DOI: 10.1038/247283A0  0.648
1974 Yehuda S, Wurtman RJ. Paradoxical thermoregulatory behaviour in rats induced by (plus)-amphetamine: blockade by alpha-adrenoceptor or dopamine receptor blocking agents. The Journal of Pharmacy and Pharmacology. 26: 210-2. PMID 4151084 DOI: 10.1111/j.2042-7158.1974.tb09259.x  0.565
1974 Chiel H, Yehuda S, Wurtman RJ. Development of tolerance in rats to the hypothermic effects of D-amphetamine and apomorphine. Life Sciences. 14: 483-8. PMID 4150950 DOI: 10.1016/0024-3205(74)90363-4  0.689
1974 Yehuda S, Wurtman RJ. Effects of d-amphetamine on body temperature and on behavioral thermoregulation in rats Biochemical Pharmacology. 23: 779. DOI: 10.1016/0006-2952(74)90131-2  0.565
1973 Hyyppä MT, Cardinali DP, Baumgarten HG, Wurtman RJ. Rapid accumulation of H3-serotonin in brains of rats receiving intraperitoneal H3-tryptophan: effects of 5,6-dihydroxytryptamine or female sex hormones. Journal of Neural Transmission. 34: 111-24. PMID 4722570 DOI: 10.1007/BF01244664  0.383
1973 Cardinali DP, Hyyppä MT, Wurtman RJ. Fate of intracisternally injected melatonin in the rat brain. Neuroendocrinology. 12: 30-40. PMID 4717238 DOI: 10.1159/000122152  0.458
1973 Lipsett D, Madras BK, Wurtman RJ, Munro HN. Serum tryptophan level after carbohydrate ingestion: selective decline in non-albumin-bound tryptophan coincident with reduction in serum free fatty acids. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 12: 57-64. PMID 4707783 DOI: 10.1016/0024-3205(73)90027-1  0.56
1973 Baliga BS, Pohorecky LA, Munro HN, Wurtman RJ. Control of adrenal medullary protein synthesis by corticosteroids. Biochimica Et Biophysica Acta. 299: 337-43. PMID 4706457 DOI: 10.1016/0005-2787(73)90358-4  0.579
1973 Hyyppä MT, Cardinali DP, Wurtman RJ. Sex-dependent increase in pineal hydroxyindole-O-methyl transferase activity after a single intraventricular injection of 6-hydroxydopamine to newborn rats. Neuroendocrinology. 11: 274-83. PMID 4699453 DOI: 10.1159/000122140  0.458
1973 Madras BK, Cohen EL, Fernstrom JD, Larin F, Munro HN, Wurtman RJ. Letter: Dietary carbohydrate increases brain tryptophan and decreases free plasma tryptophan. Nature. 244: 34-5. PMID 4582482 DOI: 10.1038/244034A0  0.677
1973 Pohorecky LA, Baliga BS, Wurtman RJ, Bartter FC. Adrenocortical control of catecholamine metabolism in the dog adrenal medulla: relationship to protein synthesis. Endocrinology. 93: 566-74. PMID 4352802 DOI: 10.1210/endo-93-3-566  0.56
1973 Ross DS, Fernstrom JD, Wurtman RJ. The role of dietary protein in generating daily rhythms in rat liver tryptophan pyrrolase and tyrosine transaminase. Metabolism: Clinical and Experimental. 22: 1175-84. PMID 4146919 DOI: 10.1016/0026-0495(73)90205-9  0.526
1973 Fernstrom JD, Larin F, Wurtman RJ. Correlation between brain tryptophan and plasma neutral amino acid levels following food consumption in rats Life Sciences. 13: 517-524. DOI: 10.1016/0024-3205(73)90044-1  0.526
1973 Lytle LD, Taam DW, Wurtman RJ, Fine J. Blockade of endotoxin-induced hypothermia by pretreatment with intracisternal 6-hydroxydopamine Life Sciences. 13: 485-492. DOI: 10.1016/0024-3205(73)90040-4  0.784
1972 Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science (New York, N.Y.). 178: 414-6. PMID 5077329 DOI: 10.1126/science.178.4059.414  0.526
1972 Cardinali DP, Larin F, Wurtman RJ. Action spectra for effects of light on hydroxyindole-o-methyl transferases in rat pineal, retina and harderian gland. Endocrinology. 91: 877-86. PMID 5051343 DOI: 10.1210/endo-91-4-877  0.458
1972 Pohorecky LA, Wurtman RJ, Taam D, Fine J. Effects of endotoxin on monoamine metabolism in the rat. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 140: 739-46. PMID 5039371 DOI: 10.3181/00379727-140-36543  0.56
1972 Cardinali DP, Wurtman RJ. Hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland. Endocrinology. 91: 247-52. PMID 5025698 DOI: 10.1210/endo-91-1-247  0.458
1972 Yehuda S, Wurtman RJ. The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures. Life Sciences. Pt. 1: Physiology and Pharmacology. 11: 851-9. PMID 4656106 DOI: 10.1016/0024-3205(72)90101-4  0.565
1972 Lytle LD, Hurko O, Romero JA, Cottman K, Leehey D, Wurtman RJ. The effects of 6-hydroxydopamine pretreatment on the accumulation of dopa and dopamine in brain and peripheral organs following L-dopa administration. Journal of Neural Transmission. 33: 63-71. PMID 4641868 DOI: 10.1007/BF01244728  0.78
1972 Yehuda S, Wurtman RJ. Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine. Nature. 240: 477-8. PMID 4565945 DOI: 10.1038/240477A0  0.565
1972 Cardinali DP, Lynch HJ, Wurtman RJ. Binding of melatonin to human and rat plasma proteins. Endocrinology. 91: 1213-8. PMID 4538504 DOI: 10.1210/endo-91-5-1213  0.476
1972 Cardinali DP, Larin F, Wurtman RJ. Control of the rat pineal gland by light spectra. Proceedings of the National Academy of Sciences of the United States of America. 69: 2003-5. PMID 4506068 DOI: 10.1073/pnas.69.8.2003  0.458
1971 Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological dependence on plasma tryptophan levels. Science (New York, N.Y.). 173: 149-52. PMID 5581909 DOI: 10.1126/science.173.3992.149  0.526
1971 Fernstrom JD, Wurtman RJ. Effect of chronic corn consumption on serotonin content of rat brain. Nature: New Biology. 234: 62-4. PMID 5288733 DOI: 10.1038/newbio234062a0  0.526
1971 Fernstrom JD, Wurtman RJ. Brain serotonin content: increase following ingestion of carbohydrate diet. Science (New York, N.Y.). 174: 1023-5. PMID 5120086 DOI: 10.1126/science.174.4013.1023  0.526
1971 Fernstrom JD, Larin F, Wurtman RJ. Daily variations in the concentrations of individual amino acids in rat plasma. Life Sciences. Pt. 1: Physiology and Pharmacology. 10: 813-9. PMID 5112236 DOI: 10.1016/0024-3205(71)90036-1  0.526
1971 Wurtman RJ, Pohorecky LA. Adrenocortical control of epinephrine synthesis in health and disease. Advances in Metabolic Disorders. 5: 53-76. PMID 4934168 DOI: 10.1016/B978-0-12-027305-8.50022-9  0.511
1970 Pohorecky LA, Piezzi RS, Wurtman RJ. Steroid induction of phenylethanolamine-N-methyl transferase in adrenomedullary explants: independence of adrenal innervation. Endocrinology. 86: 1466-8. PMID 4393295 DOI: 10.1210/endo-86-6-1466  0.56
1969 Pohorecky LA, Stamm WE, Wurtman RJ. Effects of lighting on epinephrine synthesis in the rat. Journal of Neuro-Visceral Relations. 31: 275-9. PMID 5364099 DOI: 10.1007/BF02323406  0.56
1969 Pohorecky LA, Zigmond MJ, Heimer L, Wurtman RJ. Olfactory bulb removal: effects on brain norepinephrine. Proceedings of the National Academy of Sciences of the United States of America. 62: 1052-5. PMID 5256405 DOI: 10.1073/pnas.62.4.1052  0.663
1969 Axelrod J, Shein HM, Wurtman RJ. Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture. Proceedings of the National Academy of Sciences of the United States of America. 62: 544-9. PMID 5256232 DOI: 10.1073/Pnas.62.2.544  0.466
1969 Pohorecky LA, Larin F, Wurtman RJ. Mechanism of changes in brain norepinephrine levels following olfactory bulb lesions. Life Sciences. 8: 1309-17. PMID 4391217 DOI: 10.1016/0024-3205(69)90035-6  0.56
1969 Zigmond MJ, Shoemaker WJ, Larin F, Wurtman RJ. Hepatic tyrosine transaminase rhythm: interaction of environmental lighting, food consumption and dietary protein content. The Journal of Nutrition. 98: 71-5. PMID 4389949 DOI: 10.1093/Jn/98.1.71  0.516
1969 Wurtman RJ, Shein HM, Axelrod J, Laren F. Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine. Proceedings of the National Academy of Sciences of the United States of America. 62: 749-55. PMID 4308094 DOI: 10.1073/Pnas.62.3.749  0.448
1968 Moore RY, Heller A, Bhatnager RK, Wurtman RJ, Axelrod J. Central control of the pineal gland: visual pathways. Archives of Neurology. 18: 208-18. PMID 5688808 DOI: 10.1001/Archneur.1968.00470320110013  0.456
1968 Axelrod J, Wurtman RJ. Photic and neural control of indoleamine metabolism in the rat pineal gland. Advances in Pharmacology. 6: 157-66. PMID 5688653 DOI: 10.1016/S1054-3589(08)61169-2  0.452
1968 Wurtman RJ, Larin F, Axelrod J, Shein HM, Rosasco K. Formation of melatonin and 5-hydroxyindole acetic acid from 14C-tryptophan by rat pineal glands in organ culture. Nature. 217: 953-4. PMID 5300432 DOI: 10.1038/217953A0  0.455
1968 Wurtman RJ, Axelrod J. The formation, metabolism and physiologic effects of melatonin. Advances in Pharmacology. 6: 141-51. PMID 4874443 DOI: 10.1016/S1054-3589(08)61167-9  0.467
1968 Wurtman RJ, Zigmond MJ. Pharmacologic tools in autonomic nervous system research. Anesthesiology. 29: 714-23. PMID 4874156 DOI: 10.1097/00000542-196807000-00016  0.516
1968 Wurtman RJ, Shoemaker WJ, Larin F, Zigmond M. Failure of brain norepinephrine depletion to extinguish the daily rhythm in hepatic tyrosine transaminase activity. Nature. 219: 1049-50. PMID 4386260 DOI: 10.1038/2191049A0  0.516
1968 Wurtman RJ, Casper A, Pohorecky LA, Bartter FC. Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs. Proceedings of the National Academy of Sciences of the United States of America. 61: 522-8. PMID 4301369 DOI: 10.1073/pnas.61.2.522  0.56
1968 Wurtman RJ, Axelrod J, Vesell ES, Ross GT. Species differences in inducibility of phenylethanolamine-N-methyl transferase. Endocrinology. 82: 584-90. PMID 4295959 DOI: 10.1210/endo-82-3-584  0.452
1967 Noble EP, Wurtman RJ, Axelrod J. A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. Life Sciences. 6: 281-91. PMID 6071872 DOI: 10.1016/0024-3205(67)90157-9  0.455
1967 Wurtman RJ, Axelrod J, Tramezzani J. Distribution of the adrenaline-forming enzyme in the adrenal gland of a snake, Xenodon merremii. Nature. 215: 879-80. PMID 6049749 DOI: 10.1038/215879b0  0.436
1967 Moore RY, Heller A, Wurtman RJ, Axelrod J. Visual pathway mediating pineal response to environmental light. Science (New York, N.Y.). 155: 220-3. PMID 6015532 DOI: 10.1126/Science.155.3759.220  0.44
1967 Wurtman RJ, Axelrod J, Chu EW, Heller A, Moore RY. Medial forebrain bundle lesions: blockade of effects of light on rat gonads and pineal. Endocrinology. 81: 509-14. PMID 5340425 DOI: 10.1210/Endo-81-3-509  0.45
1967 Shein HM, Wurtman RJ, Axelrod J. Synthesis of serotonin by pineal glands of the rat in organ culture. Nature. 213: 730-1. PMID 5298925 DOI: 10.1038/213730A0  0.461
1967 Wurtman RJ, Axelrod J. Daily rhythmic changes in tyrosine transaminase activity of the rat liver. Proceedings of the National Academy of Sciences of the United States of America. 57: 1594-8. PMID 4382380 DOI: 10.1073/Pnas.57.6.1594  0.46
1967 Wurtman RJ, Noble EP, Axelrod J. Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. Endocrinology. 80: 825-8. PMID 4290298 DOI: 10.1210/endo-80-5-825  0.455
1966 Wurtman RJ, Axelrod J. Effect of chlorpromazine and other drugs on the disposition of circulating melatonin. Nature. 212: 312. PMID 6008107 DOI: 10.1038/212312A0  0.448
1966 Wurtman RJ, Axelrod J. A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat. Life Sciences. 5: 665-9. PMID 5960203 DOI: 10.1016/0024-3205(66)90298-0  0.461
1966 Thoa NB, Wurtman RJ, Axelrod J. A deficient binding mechanism for norepinephrine in hearts of scorbutic guinea pigs. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 121: 267-70. PMID 5902943 DOI: 10.3181/00379727-121-30754  0.437
1966 Snyder SH, Axelrod J, Wurtman RJ. Effect of gonadal hormones on aromatic amino acid decarboxylase in the rat uterus. Endocrinology. 78: 1135-8. PMID 5296891 DOI: 10.1210/endo-78-6-1135  0.546
1965 WURTMAN RJ, AXELROD J. THE PINEAL GLAND. Scientific American. 213: 50-60. PMID 14298722 DOI: 10.1038/Scientificamerican0765-50  0.437
1965 WURTMAN RJ, AXELROD J. THE FORMATION, METABOLISM, AND PHYSIOLOGIC EFFECTS OF MELATONIN IN MAMMALS. Progress in Brain Research. 10: 520-9. PMID 14281622 DOI: 10.1016/S0079-6123(08)63469-X  0.466
1965 Wurtman RJ, Axelrod J. Adrenaline synthesis: control by the pituitary gland and adrenal glucocorticoids. Science (New York, N.Y.). 150: 1464-5. PMID 4285299 DOI: 10.1126/Science.150.3702.1464  0.45
1964 Wurtman RJ, Axelrod J, Fischer JE. Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System. Science (New York, N.Y.). 143: 1328-9. PMID 17799239 DOI: 10.1126/science.143.3612.1328  0.454
1964 WURTMAN RJ, AXELROD J, CHU EW. THE RELATION BETWEEN MELATONIN, A PINEAL SUBSTANCE, AND THE EFFECTS OF LIGHT ON THE RAT GONAD. Annals of the New York Academy of Sciences. 117: 228-30. PMID 14196643 DOI: 10.1111/J.1749-6632.1964.Tb48179.X  0.456
1964 WURTMAN RJ, AXELROD J, BARCHAS JD. AGE AND ENZYME ACTIVITY IN THE HUMAN PINEAL. The Journal of Clinical Endocrinology and Metabolism. 24: 299-301. PMID 14134071 DOI: 10.1210/jcem-24-3-299  0.429
1963 Axelrod J, Wurtman RJ, Chu EW. Effects of Melatonin, a Pineal Substance, on the Rat Ovary. Science (New York, N.Y.). 140: 378. PMID 17815768 DOI: 10.1126/science.140.3565.378-a  0.46
1963 WURTMAN RJ, AXELROD J. A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE. Biochemical Pharmacology. 12: 1439-41. PMID 14096433 DOI: 10.1016/0006-2952(63)90215-6  0.424
1963 WURTMAN RJ, AXELROD J. SEX STEROIDS, CARDIAC 3H-NOREPINEPHRINE, AND TISSUE MONOAMINE OXIDASE LEVELS IN THE RAT. Biochemical Pharmacology. 12: 1417-9. PMID 14096429 DOI: 10.1016/0006-2952(63)90211-9  0.458
1963 WURTMAN RJ, AXELROD J, PHILLIPS LS. MELATONIN SYNTHESIS IN THE PINEAL GLAND: CONTROL BY LIGHT. Science (New York, N.Y.). 142: 1071-3. PMID 14068225 DOI: 10.1126/Science.142.3595.1071  0.457
1963 WURTMAN RJ, KOPIN IJ, AXELROD J. Thyroid function and the cardiac disposition of catecholamines. Endocrinology. 73: 63-74. PMID 14002085 DOI: 10.1210/Endo-73-1-63  0.456
1963 WURTMAN RJ, CHU EW, AXELROD J. Relation between the oestrous cycle and the binding of catecholamines in the rat uterus. Nature. 198: 547-8. PMID 14002084 DOI: 10.1038/198547A0  0.446
1963 WURTMAN RJ, AXELROD J, CHU EW. Melatonin, a pineal substance: effect on the rat ovary. Science (New York, N.Y.). 141: 277-8. PMID 14002083 DOI: 10.1126/Science.141.3577.277  0.463
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