Amy M. Pooler - Publications

King's College London, London, UK 

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wegmann S, DeVos SL, Zeitler B, Marlen K, Bennett RE, Perez-Rando M, MacKenzie D, Yu Q, Commins C, Bannon RN, Corjuc BT, Chase A, Diez L, Nguyen HB, Hinkley S, ... ... Pooler AM, et al. Persistent repression of tau in the brain using engineered zinc finger protein transcription factors. Science Advances. 7. PMID 33741591 DOI: 10.1126/sciadv.abe1611  0.462
2019 Rieker C, Migliavacca E, Vaucher A, Mayer FC, Baud G, Marquis J, Charpagne A, Hegde N, Guignard L, McLachlan M, Pooler AM. Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312261. PMID 31315437 DOI: 10.1161/ATVBAHA.118.312261  0.329
2017 Croft CL, Wade MA, Kurbatskaya K, Mastrandreas P, Hughes MM, Phillips EC, Pooler AM, Perkinton MS, Hanger DP, Noble W. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death & Disease. 8: e2671. PMID 28300838 DOI: 10.1038/Cddis.2017.97  0.718
2017 Pickett EK, Henstridge CM, Allison E, Pitstick R, Pooler A, Wegmann S, Carlson G, Hyman BT, Spires-Jones TL. Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease. Synapse (New York, N.Y.). PMID 28196395 DOI: 10.1002/Syn.21965  0.505
2016 Lau DH, Hogseth M, Phillips EC, O'Neill MJ, Pooler AM, Noble W, Hanger DP. Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease. Acta Neuropathologica Communications. 4: 49. PMID 27193083 DOI: 10.1186/S40478-016-0317-4  0.742
2016 Ramos-Rodriguez JJ, Spires-Jones T, Pooler AM, Lechuga-Sancho AM, Bacskai BJ, Garcia-Alloza M. Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease. Molecular Neurobiology. PMID 27177549 DOI: 10.1007/S12035-016-9921-3  0.435
2016 Gilley J, Ando K, Seereeram A, Rodríguez-Martín T, Pooler AM, Sturdee L, Anderton BH, Brion JP, Hanger DP, Coleman MP. Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice. Neurobiology of Aging. 39: 1-18. PMID 26923397 DOI: 10.1016/j.neurobiolaging.2015.11.028  0.739
2015 Wegmann S, Maury EA, Kirk MJ, Saqran L, Roe A, DeVos SL, Nicholls S, Fan Z, Takeda S, Cagsal-Getkin O, William CM, Spires-Jones TL, Pitstick R, Carlson GA, Pooler AM, et al. Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity. The Embo Journal. PMID 26538322 DOI: 10.15252/Embj.201592748  0.588
2015 Rodríguez-Martín T, Pooler AM, Lau DH, Mórotz GM, De Vos KJ, Gilley J, Coleman MP, Hanger DP. Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons. Neurobiology of Disease. 85: 1-10. PMID 26459111 DOI: 10.1016/j.nbd.2015.10.007  0.713
2015 Pooler AM, Polydoro M, Maury EA, Nicholls SB, Reddy SM, Wegmann S, William C, Saqran L, Cagsal-Getkin O, Pitstick R, Beier DR, Carlson GA, Spires-Jones TL, Hyman BT. Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease. Acta Neuropathologica Communications. 3: 14. PMID 25853174 DOI: 10.1186/S40478-015-0199-X  0.471
2015 Wegmann S, Maury EA, Kirk MJ, Saqran L, Roe AD, Fan Z, Nicholls SB, DeVos SL, Takeda S, William CM, Spires-Jones TL, Pitstick R, Carlson GA, Pooler A, Hyman BT. O2-06-01: Lack of endogenous tau permits tau spreading and protects against tau toxicity in transgenic mice Alzheimer's & Dementia. 11: P186-P186. DOI: 10.1016/J.Jalz.2015.07.159  0.488
2014 Ando K, Laborde Q, Lazar A, Godefroy D, Youssef I, Amar M, Pooler A, Potier MC, Delatour B, Duyckaerts C. Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D. Acta Neuropathologica. 128: 457-9. PMID 25069432 DOI: 10.1007/S00401-014-1322-Y  0.429
2014 Hanger DP, Lau DH, Phillips EC, Bondulich MK, Guo T, Woodward BW, Pooler AM, Noble W. Intracellular and extracellular roles for tau in neurodegenerative disease. Journal of Alzheimer's Disease : Jad. 40: S37-45. PMID 24595196 DOI: 10.3233/Jad-132054  0.747
2014 Polydoro M, Dzhala VI, Pooler AM, Nicholls SB, McKinney AP, Sanchez L, Pitstick R, Carlson GA, Staley KJ, Spires-Jones TL, Hyman BT. Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model. Acta Neuropathologica. 127: 257-70. PMID 24271788 DOI: 10.1007/S00401-013-1215-5  0.584
2014 Pooler AM, Noble W, Hanger DP. A role for tau at the synapse in Alzheimer's disease pathogenesis. Neuropharmacology. 76: 1-8. PMID 24076336 DOI: 10.1016/J.Neuropharm.2013.09.018  0.677
2014 Lau DH, Pooler AM, Noble W, Hanger DP. P1-115: IDENTIFICATION OF THE BINDING SITE BETWEEN TAU AND FYN: CONSEQUENCES FOR TAU RELEASE? Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.352  0.585
2013 Pooler AM, Polydoro M, Wegmann S, Nicholls SB, Spires-Jones TL, Hyman BT. Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets. Alzheimer's Research & Therapy. 5: 49. PMID 24152385 DOI: 10.1186/Alzrt214  0.62
2013 Pooler AM, Polydoro M, Wegmann SK, Pitstick R, Kay KR, Sanchez L, Carlson GA, Gomez-Isla T, Albers MW, Spires-Jones TL, Hyman BT. Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology. The Journal of Comparative Neurology. 521: 4236-48. PMID 23839581 DOI: 10.1002/Cne.23411  0.5
2013 Crimins JL, Pooler A, Polydoro M, Luebke JI, Spires-Jones TL. The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease. Ageing Research Reviews. 12: 757-63. PMID 23528367 DOI: 10.1016/J.Arr.2013.03.002  0.471
2013 Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. Embo Reports. 14: 389-94. PMID 23412472 DOI: 10.1038/Embor.2013.15  0.723
2013 Pooler A, Phillips E, Lau D, Noble W, Hanger D. O2-01-03: Neuronal activity regulates secretion of endogenous tau Alzheimer's & Dementia. 9: P314-P315. DOI: 10.1016/J.Jalz.2013.04.137  0.656
2012 Richet E, Pooler AM, Rodriguez T, Novoselov SS, Schmidtke G, Groettrup M, Hanger DP, Cheetham ME, van der Spuy J. NUB1 modulation of GSK3β reduces tau aggregation. Human Molecular Genetics. 21: 5254-67. PMID 22965877 DOI: 10.1093/hmg/dds376  0.721
2012 Pooler AM, Usardi A, Evans CJ, Philpott KL, Noble W, Hanger DP. Dynamic association of tau with neuronal membranes is regulated by phosphorylation. Neurobiology of Aging. 33: 431.e27-38. PMID 21388709 DOI: 10.1016/J.Neurobiolaging.2011.01.005  0.729
2011 Noble W, Pooler AM, Hanger DP. Advances in tau-based drug discovery. Expert Opinion On Drug Discovery. 6: 797-810. PMID 22003359 DOI: 10.1517/17460441.2011.586690  0.685
2011 Usardi A, Pooler AM, Seereeram A, Reynolds CH, Derkinderen P, Anderton B, Hanger DP, Noble W, Williamson R. Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau. The Febs Journal. 278: 2927-37. PMID 21692989 DOI: 10.1111/J.1742-4658.2011.08218.X  0.737
2011 Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W. Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture. Cell Death & Disease. 2: e167. PMID 21633390 DOI: 10.1038/Cddis.2011.50  0.68
2010 Pooler AM, Hanger DP. Functional implications of the association of tau with the plasma membrane. Biochemical Society Transactions. 38: 1012-5. PMID 20658995 DOI: 10.1042/BST0381012  0.715
2010 Pooler AM, Usardi A, Hanger DP. P1-362: Dynamic association of tau with neuronal membranes is regulated by phosphorylation and the tyrosine kinase fyn Alzheimer's & Dementia. 6: S277-S278. DOI: 10.1016/j.jalz.2010.05.916  0.684
2009 Pooler AM, Hanger DP. P3-208: Phosphorylation-dependent association of tau with the neuronal membrane Alzheimer's & Dementia. 5: P404-P404. DOI: 10.1016/j.jalz.2009.04.981  0.693
2006 Pooler AM, Xi SC, Wurtman RJ. The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons. Journal of Neurochemistry. 97: 716-23. PMID 16573653 DOI: 10.1111/j.1471-4159.2006.03763.x  0.544
2005 Wang L, Pooler AM, Albrecht MA, Wurtman RJ. Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats. Journal of Molecular Neuroscience : Mn. 27: 137-45. PMID 16055952 DOI: 10.1385/JMN:27:1:137  0.486
2005 Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]. Neuroscience. 134: 207-14. PMID 15939540 DOI: 10.1016/j.neuroscience.2005.03.050  0.475
2005 Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Erratum to “Uridine enhances neurite outgrowth in nerve growth factor-differentiated pheochromocytoma cells” [Neuroscience 134 (2005) 207–214] Neuroscience. 135: 657. DOI: 10.1016/J.Neuroscience.2005.07.044  0.4
2004 Pooler AM, Arjona AA, Lee RK, Wurtman RJ. Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia. Neuroscience Letters. 362: 127-30. PMID 15193769 DOI: 10.1016/j.neulet.2004.03.013  0.476
2002 Arjona AA, Pooler AM, Lee RK, Wurtman RJ. Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. Brain Research. 951: 135-40. PMID 12231467 DOI: 10.1016/S0006-8993(02)03153-0  0.47
Show low-probability matches.