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David R. Hinton, MD FRCPC Pathol - Publications

Affiliations: 
Pathology, Neurosurgery, Ophthamology  University of Southern California, Los Angeles, CA, United States 
Area:
Aging, Gene Therapy, Vision Research, Cellular Neurobiology
Website:
http://www.usc.edu/programs/pibbs/site/faculty/hinton_d.htm

339 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, et al. Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo. Scientific Reports. 11: 6286. PMID 33737600 DOI: 10.1038/s41598-021-85631-6  0.8
2021 Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, ... ... Hinton DR, et al. Cytoplasmic synthesis of endogenous complementary DNA via reverse transcription and implications in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526699 DOI: 10.1073/pnas.2022751118  0.4
2020 Sreekumar PG, Hinton DR, Kannan R. The Emerging Role of Senescence in Ocular Disease. Oxidative Medicine and Cellular Longevity. 2020: 2583601. PMID 32215170 DOI: 10.1155/2020/2583601  0.6
2020 Shi H, Koronyo Y, Rentsendorj A, Regis GC, Sheyn J, Fuchs DT, Kramerov AA, Ljubimov AV, Dumitrascu OM, Rodriguez AR, Barron E, Hinton DR, Black KL, Miller CA, Mirzaei N, et al. Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta Neuropathologica. PMID 32043162 DOI: 10.1007/S00401-020-02134-W  0.56
2019 Kashani AH, Martynova A, Koss M, Brant R, Zhu DH, Lebkowski J, Hinton D, Clegg D, Humayun MS. Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model. Advances in Experimental Medicine and Biology. 1185: 569-574. PMID 31884672 DOI: 10.1007/978-3-030-27378-1_93  0.36
2019 Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study. Ophthalmology. Retina. PMID 31786135 DOI: 10.1016/J.Oret.2019.09.017  0.36
2019 Li Z, Sreekumar PG, Peddi S, Hinton DR, Kannan R, MacKay JA. The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress. Nanomedicine : Nanotechnology, Biology, and Medicine. 102111. PMID 31655204 DOI: 10.1016/J.Nano.2019.102111  0.6
2019 Martinez-Camarillo JC, Spee CK, Chen M, Rodriguez A, Nimmagadda K, Trujillo-Sanchez GP, Hinton DR, Giarola A, Pikov V, Sridhar A, Humayun MS, Weitz AC. Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures. Investigative Ophthalmology & Visual Science. 60: 4303-4309. PMID 31618767 DOI: 10.1167/Iovs.18-25613  0.36
2019 Su F, Spee C, Araujo E, Barron E, Wang M, Ghione C, Hinton DR, Nusinowitz S, Kannan R, Reddy ST, Farias-Eisner R. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. International Journal of Molecular Sciences. 20. PMID 31569695 DOI: 10.3390/Ijms20194807  0.6
2019 Lin TC, Wang LC, Yue L, Zhang Y, Falabella P, Zhu D, Hinton DR, Rao NA, Birch DG, Spencer R, Dorn JD, Humayun MS. Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System. Translational Vision Science & Technology. 8: 31. PMID 31171998 DOI: 10.1167/Tvst.8.3.31  0.8
2019 Wang M, Lau LI, Sreekumar PG, Spee C, Hinton DR, Sadda SR, Kannan R. Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells. Investigative Ophthalmology & Visual Science. 60: 500-516. PMID 30707752 DOI: 10.1167/Iovs.18-25686  0.6
2019 Rentsendorj A, Koronyo Y, Fuchs D, Sheyn J, Regis GC, Mirzaei N, Barron E, Black KL, Hinton DR, Miller CA, Koronyo-Hamaoui M. P2-193: Early Retinal Amyloid-Associated Pathological Changes In Mci And Ad Patients Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2600  0.56
2018 Trujillo-Sanchez GP, Martinez-Camarillo JC, Spee CK, Hinton DR, Humayun MS, Weitz AC. Stereological Method in Optical Coherence Tomography for In Vivo Evaluation of Laser-Induced Choroidal Neovascularization. Ophthalmic Surgery, Lasers & Imaging Retina. 49: e65-e74. PMID 30222821 DOI: 10.3928/23258160-20180907-09  0.36
2018 Thomas BB, Zhu D, Lin TC, Kim YC, Seiler MJ, Martinez-Camarillo JC, Lin B, Shad Y, Hinton DR, Humayun MS. A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 30215097 DOI: 10.1007/S00417-018-4134-2  0.8
2018 Sreekumar PG, Li Z, Wang W, Spee C, Hinton DR, Kannan R, Andrew MacKay J. Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29778783 DOI: 10.1016/J.Jconrel.2018.05.014  0.6
2018 Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, et al. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science Translational Medicine. 10. PMID 29618560 DOI: 10.1126/Scitranslmed.Aao4097  0.8
2018 Maya K, Rentsendorj A, Barron E, Fuchs D, Miller CA, Black KL, Hinton DR, Meli G, Koronyo Y. P4-254: IDENTIFICATION OF INFLAMMATORY PROCESSES SURROUNDING AMYLOID-β DEPOSITS IN THE RETINA OF MCI AND AD PATIENTS Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.076  0.56
2017 Jiao C, Eliott D, Spee C, He S, Wang K, Mullins RF, Hinton DR, Sohn EH. APOPTOSIS AND ANGIOFIBROSIS IN DIABETIC TRACTIONAL MEMBRANES AFTER VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: Results of a Prospective Trial. Report No. 2. Retina (Philadelphia, Pa.). PMID 29190236 DOI: 10.1097/Iae.0000000000001952  0.88
2017 Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, ... ... Hinton DR, et al. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature Medicine. PMID 29176737 DOI: 10.1038/Nm.4450  0.4
2017 Fernandes RAB, Stefanini FR, Falabella P, Koss MJ, Wells T, Diniz B, Ribeiro R, Schor P, Maia M, Penha FM, Hinton DR, Tai YC, Humayun M. Development of a new tissue injector for subretinal transplantation of human embryonic stem cell derived retinal pigmented epithelium. International Journal of Retina and Vitreous. 3: 41. PMID 29093829 DOI: 10.1186/s40942-017-0095-6  0.36
2017 Lin TC, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB. Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells International. 2017: 9428176. PMID 28928775 DOI: 10.1155/2017/9428176  0.8
2017 Minasyan L, Sreekumar PG, Hinton DR, Kannan R. Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells. Oxidative Medicine and Cellular Longevity. 2017: 1675230. PMID 28814984 DOI: 10.1155/2017/1675230  0.6
2017 Koronyo Y, Biggs D, Barron E, Boyer DS, Pearlman JA, Au WJ, Kile SJ, Blanco A, Fuchs DT, Ashfaq A, Frautschy S, Cole GM, Miller CA, Hinton DR, Verdooner SR, et al. Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease. Jci Insight. 2. PMID 28814675 DOI: 10.1172/Jci.Insight.93621  0.56
2017 Sreekumar PG, Hinton DR, Kannan R. Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin. Neural Regeneration Research. 12: 35-38. PMID 28250736 DOI: 10.4103/1673-5374.198970  0.6
2016 Matsunaga D, Sreekumar PG, Ishikawa K, Terasaki H, Barron E, Cohen P, Kannan R, Hinton DR. Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione. Plos One. 11: e0165150. PMID 27783653 DOI: 10.1371/Journal.Pone.0165150  0.6
2016 Savarin C, Bergmann CC, Hinton DR, Stohlman SA. Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis. Frontiers in Immunology. 7: 370. PMID 27708643 DOI: 10.3389/Fimmu.2016.00370  0.68
2016 Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS. Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 27335025 DOI: 10.1007/S00417-016-3386-Y  0.8
2016 Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR, Humayun MS. Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Investigative Ophthalmology & Visual Science. 57: 2877-2887. PMID 27233037 DOI: 10.1167/Iovs.16-19238  0.8
2016 Brant Fernandes RA, Koss MJ, Falabella P, Stefanini FR, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO, Chader G, Humayun MS. An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surgery, Lasers & Imaging Retina. 47: 342-351. PMID 27065374 DOI: 10.3928/23258160-20160324-07  0.36
2016 Kochounian H, Zhang Z, Spee C, Hinton DR, Fong HK. Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9. Molecular Vision. 22: 213-23. PMID 27011730  0.6
2016 Sreekumar PG, Ishikawa K, Spee C, Mehta HH, Wan J, Yen K, Cohen P, Kannan R, Hinton DR. The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction. Investigative Ophthalmology & Visual Science. 57: 1238-1253. PMID 26990160 DOI: 10.1167/Iovs.15-17053  0.6
2016 Valentin-Torres A, Savarin C, Hinton DR, Phares TW, Bergmann CC, Stohlman SA. Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis. Journal of Neuroinflammation. 13: 46. PMID 26906225 DOI: 10.1186/S12974-016-0513-Y  0.68
2016 Ishikawa K, Sreekumar PG, Spee C, Nazari H, Zhu D, Kannan R, Hinton DR. αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition. The American Journal of Pathology. PMID 26878210 DOI: 10.1016/J.Ajpath.2015.11.014  0.88
2015 Ishikawa K, He S, Terasaki H, Nazari H, Zhang H, Spee C, Kannan R, Hinton DR. Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy. Scientific Reports. 5: 16386. PMID 26552368 DOI: 10.1038/Srep16386  0.88
2015 He S, Barron E, Ishikawa K, Nazari Khanamiri H, Spee C, Zhou P, Kase S, Wang Z, Dustin LD, Hinton DR. Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy. Investigative Ophthalmology & Visual Science. 56: 5579-89. PMID 26305530 DOI: 10.1167/Iovs.14-16258  0.88
2015 Zhang H, He S, Spee C, Ishikawa K, Hinton DR. SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization. Cytokine. 76: 549-52. PMID 26174951 DOI: 10.1016/J.Cyto.2015.06.019  0.88
2015 Butchi N, Kapil P, Puntambekar S, Stohlman SA, Hinton DR, Bergmann CC. Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis. Journal of Virology. 89: 9299-312. PMID 26136579 DOI: 10.1128/Jvi.01199-15  0.68
2015 Puntambekar SS, Hinton DR, Yin X, Savarin C, Bergmann CC, Trapp BD, Stohlman SA. Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination. Glia. PMID 26132901 DOI: 10.1002/Glia.22880  0.68
2015 Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rawland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS. Stem cell based therapies for age-related macular degeneration: the promises and the challenges. Progress in Retinal and Eye Research. PMID 26113213 DOI: 10.1016/J.Preteyeres.2015.06.004  0.88
2015 Kannan R, Sreekumar PG, Hinton DR. Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration. Biochimica Et Biophysica Acta. PMID 26026469 DOI: 10.1016/J.Bbagen.2015.05.016  0.6
2015 Savarin C, Hinton DR, Valentin-Torres A, Chen Z, Trapp BD, Bergmann CC, Stohlman SA. Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis. Journal of Neuroinflammation. 12: 79. PMID 25896970 DOI: 10.1186/S12974-015-0293-9  0.68
2015 Chan N, He S, Spee CK, Ishikawa K, Hinton DR. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. Plos One. 10: e0120587. PMID 25807249 DOI: 10.1371/Journal.Pone.0120587  0.88
2015 Ishikawa K, Kannan R, Hinton DR. Molecular mechanisms of subretinal fibrosis in age-related macular degeneration. Experimental Eye Research. PMID 25773985 DOI: 10.1016/J.Exer.2015.03.009  0.6
2015 Hirsch L, Nazari H, Sreekumar PG, Kannan R, Dustin L, Zhu D, Barron E, Hinton DR. TGF-β2 secretion from RPE decreases with polarization and becomes apically oriented. Cytokine. 71: 394-6. PMID 25496702 DOI: 10.1016/J.Cyto.2014.11.014  0.88
2015 Hsiung J, Zhu D, Hinton DR. Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. Stem Cells Translational Medicine. 4: 10-20. PMID 25411476 DOI: 10.5966/Sctm.2014-0205  0.8
2015 Puntambekar SS, Hinton DR, Yin X, Savarin C, Bergmann CC, Trapp BD, Stohlman SA. Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination Glia. DOI: 10.1002/glia.22880  0.88
2014 Kannan R, Hinton DR. Sodium iodate induced retinal degeneration: new insights from an old model. Neural Regeneration Research. 9: 2044-5. PMID 25657718 DOI: 10.4103/1673-5374.147927  0.88
2014 Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, ... ... Hinton DR, et al. IL-18 is not therapeutic for neovascular age-related macular degeneration. Nature Medicine. 20: 1372-5. PMID 25473914 DOI: 10.1038/Nm.3671  0.88
2014 Sur A, Kesaraju S, Prentice H, Ayyanathan K, Baronas-Lowell D, Zhu D, Hinton DR, Blanks J, Weissbach H. Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α. Proceedings of the National Academy of Sciences of the United States of America. 111: 16754-9. PMID 25385631 DOI: 10.1073/Pnas.1419576111  0.88
2014 Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, et al. DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 111: 16082-7. PMID 25349431 DOI: 10.1073/Pnas.1403814111  0.88
2014 Hwang M, Phares TW, Hinton DR, Stohlman SA, Bergmann CC, Min B. Distinct CD4 T cell effects on primary versus recall CD8 T cell responses during viral encephalomyelitis. Immunology. PMID 25187405 DOI: 10.1111/Imm.12378  0.68
2014 de Aquino MT, Kapil P, Hinton DR, Phares TW, Puntambekar SS, Savarin C, Bergmann CC, Stohlman SA. IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination. Journal of Immunology (Baltimore, Md. : 1950). 193: 285-94. PMID 24890725 DOI: 10.4049/Jimmunol.1400058  0.88
2014 Zhou P, Kannan R, Spee C, Sreekumar PG, Dou G, Hinton DR. Protection of retina by αB crystallin in sodium iodate induced retinal degeneration. Plos One. 9: e98275. PMID 24874187 DOI: 10.1371/Journal.Pone.0098275  0.6
2014 Wang W, Sreekumar PG, Valluripalli V, Shi P, Wang J, Lin YA, Cui H, Kannan R, Hinton DR, MacKay JA. Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 191: 4-14. PMID 24780268 DOI: 10.1016/J.Jconrel.2014.04.028  0.88
2014 Sonoda S, Nagineni CN, Kitamura M, Spee C, Kannan R, Hinton DR. Ceramide inhibits connective tissue growth factor expression by human retinal pigment epithelial cells. Cytokine. 68: 137-40. PMID 24758915 DOI: 10.1016/J.Cyto.2014.03.011  0.6
2014 Kapil P, Stohlman SA, Hinton DR, Bergmann CC. PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis. Journal of Neuroimmunology. 270: 1-12. PMID 24642385 DOI: 10.1016/J.Jneuroim.2014.02.012  0.68
2014 Butchi NB, Hinton DR, Stohlman SA, Kapil P, Fensterl V, Sen GC, Bergmann CC. Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages. Journal of Virology. 88: 1051-64. PMID 24198415 DOI: 10.1128/Jvi.02272-13  0.88
2013 de Aquino MT, Puntambekar SS, Savarin C, Bergmann CC, Phares TW, Hinton DR, Stohlman SA. Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system. Virology. 447: 112-20. PMID 24210105 DOI: 10.1016/J.Virol.2013.08.030  0.88
2013 Savarin C, Bergmann CC, Hinton DR, Stohlman SA. MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis. Asn Neuro. 5: e00127. PMID 24156369 DOI: 10.1042/An20130033  0.68
2013 Kerur N, Hirano Y, Tarallo V, Fowler BJ, Bastos-Carvalho A, Yasuma T, Yasuma R, Kim Y, Hinton DR, Kirschning CJ, Gelfand BD, Ambati J. TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy. Investigative Ophthalmology & Visual Science. 54: 7395-401. PMID 24114535 DOI: 10.1167/iovs.13-12500  0.88
2013 Phares TW, DiSano KD, Hinton DR, Hwang M, Zajac AJ, Stohlman SA, Bergmann CC. IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis. Journal of Neuroimmunology. 263: 43-54. PMID 23992866 DOI: 10.1016/J.Jneuroim.2013.07.019  0.88
2013 Ribeiro RM, Oregon A, Diniz B, Fernandes RB, Koss MJ, Charafeddin W, Hu Y, Thomas P, Thomas BB, Maia M, Chader GJ, Hinton DR, Humayun MS. In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance. Ophthalmic Surgery, Lasers & Imaging Retina. 44: 380-4. PMID 23883533 DOI: 10.3928/23258160-20130715-09  0.88
2013 Diniz B, Thomas P, Thomas B, Ribeiro R, Hu Y, Brant R, Ahuja A, Zhu D, Liu L, Koss M, Maia M, Chader G, Hinton DR, Humayun MS. Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Investigative Ophthalmology & Visual Science. 54: 5087-96. PMID 23833067 DOI: 10.1167/Iovs.12-11239  0.88
2013 He S, Li X, Chan N, Hinton DR. Review: Epigenetic mechanisms in ocular disease. Molecular Vision. 19: 665-74. PMID 23559860  0.88
2013 Sreekumar PG, Chothe P, Sharma KK, Baid R, Kompella U, Spee C, Kannan N, Manh C, Ryan SJ, Ganapathy V, Kannan R, Hinton DR. Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells. Investigative Ophthalmology & Visual Science. 54: 2787-98. PMID 23532520 DOI: 10.1167/Iovs.12-11571  0.88
2013 Phares TW, Stohlman SA, Hinton DR, Bergmann CC. Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis. Journal of Virology. 87: 3382-92. PMID 23302888 DOI: 10.1128/Jvi.03307-12  0.68
2013 Zhu G, Ye R, Jung DY, Barron E, Friedline RH, Benoit VM, Hinton DR, Kim JK, Lee AS. GRP78 plays an essential role in adipogenesis and postnatal growth in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 955-64. PMID 23180827 DOI: 10.1096/Fj.12-213330  0.56
2012 Phares TW, Stohlman SA, Hinton DR, Bergmann CC. Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis. Journal of Neuroinflammation. 9: 269. PMID 23237504 DOI: 10.1186/1742-2094-9-269  0.68
2012 Sohn EH, He S, Kim LA, Salehi-Had H, Javaheri M, Spee C, Dustin L, Hinton DR, Eliott D. Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 1127-34. PMID 22965588 DOI: 10.1001/Archophthalmol.2012.1611  0.88
2012 Gundimeda U, McNeill TH, Elhiani AA, Schiffman JE, Hinton DR, Gopalakrishna R. Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε. The Journal of Biological Chemistry. 287: 34694-708. PMID 22879598 DOI: 10.1074/Jbc.M112.356899  0.88
2012 Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich S, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, et al. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 13781-6. PMID 22869729 DOI: 10.1073/Pnas.1206494109  0.88
2012 Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS. A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48: 186-91. PMID 22868580 DOI: 10.1159/000338749  0.88
2012 Hindinger C, Bergmann CC, Hinton DR, Phares TW, Parra GI, Hussain S, Savarin C, Atkinson RD, Stohlman SA. IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability. Plos One. 7: e42088. PMID 22848713 DOI: 10.1371/Journal.Pone.0042088  0.68
2012 Dou G, Sreekumar PG, Spee C, He S, Ryan SJ, Kannan R, Hinton DR. Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction. Free Radical Biology & Medicine. 53: 1111-22. PMID 22781655 DOI: 10.1016/J.Freeradbiomed.2012.06.042  0.88
2012 Kannan R, Sreekumar PG, Hinton DR. Novel roles for α-crystallins in retinal function and disease. Progress in Retinal and Eye Research. 31: 576-604. PMID 22721717 DOI: 10.1016/J.Preteyeres.2012.06.001  0.6
2012 Savarin C, Stohlman SA, Hinton DR, Ransohoff RM, Cua DJ, Bergmann CC. IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils. Journal of Neuroinflammation. 9: 104. PMID 22642802 DOI: 10.1186/1742-2094-9-104  0.68
2012 Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, ... ... Hinton DR, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 149: 847-59. PMID 22541070 DOI: 10.1016/J.Cell.2012.03.036  0.88
2012 Sreekumar PG, Spee C, Ryan SJ, Cole SP, Kannan R, Hinton DR. Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. Plos One. 7: e33420. PMID 22442691 DOI: 10.1371/Journal.Pone.0033420  0.88
2012 Xu J, Zhu D, Sonoda S, He S, Spee C, Ryan SJ, Hinton DR. Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9. Angiogenesis. 15: 213-27. PMID 22392094 DOI: 10.1007/S10456-012-9254-4  0.88
2012 Lu B, Zhu D, Hinton D, Humayun MS, Tai YC. Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells. Biomedical Microdevices. 14: 659-67. PMID 22391881 DOI: 10.1007/S10544-012-9645-8  0.88
2012 Phares TW, Stohlman SA, Hwang M, Min B, Hinton DR, Bergmann CC. CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. Journal of Virology. 86: 2416-27. PMID 22205741 DOI: 10.1128/Jvi.06797-11  0.68
2012 Gonnermann J, Klein JP, Klamann MKJ, Maier A, Pleyer U, Joussen AM, Bertelmann E, Ribeiro JCML, Fechine FV, Ribeiro MZML, Barreiro EJ, Lima LM, Ricardo NMPS, Moraes MEAd, Moraes MOd, ... ... Hinton DR, et al. Contents Vol. 48, 2012 Ophthalmic Research. 48. DOI: 10.1159/000337110  0.8
2012 Lu B, Zhu D, Hinton D, Humayun MS, Tai YC. A 3D parylene scaffold cage for culturing retinal pigment epithelial cells Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 741-744. DOI: 10.1109/MEMSYS.2012.6170292  0.88
2012 Friedlander M, Hinton DR. Stem Cells and Cellular Therapy Retina Fifth Edition. 1: 669-688. DOI: 10.1016/B978-1-4557-0737-9.00035-7  0.88
2011 Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, ... ... Hinton DR, et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell. 20: 768-80. PMID 22172722 DOI: 10.1016/J.Ccr.2011.10.016  0.88
2011 Kannan R, Sreekumar PG, Hinton DR. VEGF and PEDF secretion in ARPE-19 and fhRPE cells. Investigative Ophthalmology & Visual Science. 52: 9047. PMID 22104197 DOI: 10.1167/Iovs.11-8737  0.6
2011 Sreekumar PG, Hinton DR, Kannan R. Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World Journal of Biological Chemistry. 2: 184-92. PMID 21909460 DOI: 10.4331/Wjbc.V2.I8.184  0.6
2011 Khankan R, Oliver N, He S, Ryan SJ, Hinton DR. Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII. Investigative Ophthalmology & Visual Science. 52: 5068-78. PMID 21571675 DOI: 10.1167/Iovs.11-7191  0.88
2011 Puntambekar SS, Bergmann CC, Savarin C, Karp CL, Phares TW, Parra GI, Hinton DR, Stohlman SA. Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis. Journal of Virology. 85: 6702-13. PMID 21525347 DOI: 10.1128/Jvi.00200-11  0.88
2011 Marques CP, Kapil P, Hinton DR, Hindinger C, Nutt SL, Ransohoff RM, Phares TW, Stohlman SA, Bergmann CC. CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis. Journal of Virology. 85: 6136-47. PMID 21507985 DOI: 10.1128/Jvi.00202-11  0.88
2011 Couldwell WT, Surnock AA, Tobia AJ, Cabana BE, Stillerman CB, Forsyth PA, Appley AJ, Spence AM, Hinton DR, Chen TC. A phase 1/2 study of orally administered synthetic hypericin for treatment of recurrent malignant gliomas. Cancer. 117: 4905-15. PMID 21456013 DOI: 10.1002/Cncr.26123  0.88
2011 Xu J, Zhu D, He S, Spee C, Ryan SJ, Hinton DR. Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2221-33. PMID 21411747 DOI: 10.1096/Fj.10-178350  0.88
2011 Sadler TR, Nguyen PT, Yang J, Givrad TK, Mayer EA, Maarek JM, Hinton DR, Holschneider DP. Antenatal maternal stress alters functional brain responses in adult offspring during conditioned fear. Brain Research. 1385: 163-74. PMID 21300034 DOI: 10.1016/J.Brainres.2011.01.104  0.88
2011 Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, ... ... Hinton DR, et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 471: 325-30. PMID 21297615 DOI: 10.1038/Nature09830  0.88
2011 Lee NG, Berry JL, Lee TC, Wang AT, Honowitz S, Murphree AL, Varshney N, Hinton DR, Fawzi AA. Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro. Investigative Ophthalmology & Visual Science. 52: 3868-73. PMID 21273549 DOI: 10.1167/Iovs.10-6501  0.88
2011 Chothe PP, Gnana-Prakasam JP, Ananth S, Martin PM, Kannan R, Hinton DR, Smith SB, Ganapathy V. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. Biochemical and Biophysical Research Communications. 405: 244-9. PMID 21219868 DOI: 10.1016/J.Bbrc.2011.01.018  0.88
2011 Phares TW, Marques CP, Stohlman SA, Hinton DR, Bergmann CC. Factors supporting intrathecal humoral responses following viral encephalomyelitis. Journal of Virology. 85: 2589-98. PMID 21191015 DOI: 10.1128/Jvi.02260-10  0.88
2011 Zhu D, Deng X, Spee C, Sonoda S, Hsieh CL, Barron E, Pera M, Hinton DR. Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Investigative Ophthalmology & Visual Science. 52: 1573-85. PMID 21087957 DOI: 10.1167/Iovs.10-6413  0.8
2011 Abdallah W, Ameri H, Barron E, Chader GJ, Greenbaum E, Hinton DR, Humayun MS. Vitreal oxygenation in retinal ischemia reperfusion. Investigative Ophthalmology & Visual Science. 52: 1035-42. PMID 21051734 DOI: 10.1167/Iovs.09-4516  0.88
2011 Lu B, Liu Z, Liu L, Zhu D, Hinton D, Thomas B, Humayun MS, Tai YC. Semipermeable parylene membrane as an artificial Bruch's membrane 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, Transducers'11. 950-953. DOI: 10.1109/TRANSDUCERS.2011.5969376  0.88
2010 Ye R, Mareninova OA, Barron E, Wang M, Hinton DR, Pandol SJ, Lee AS. Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis. The American Journal of Pathology. 177: 2827-36. PMID 20971738 DOI: 10.2353/Ajpath.2010.100368  0.56
2010 Sreekumar PG, Kannan R, Kitamura M, Spee C, Barron E, Ryan SJ, Hinton DR. αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. Plos One. 5: e12578. PMID 20949024 DOI: 10.1371/Journal.Pone.0012578  0.88
2010 Gundimeda U, McNeill TH, Schiffman JE, Hinton DR, Gopalakrishna R. Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species. Journal of Neuroscience Research. 88: 3644-55. PMID 20936703 DOI: 10.1002/Jnr.22519  0.88
2010 Phares TW, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5607-18. PMID 20876353 DOI: 10.4049/Jimmunol.1001984  0.68
2010 Lim JI, Spee C, Hinton DR. A comparison of hypoxia-inducible factor-α in surgically excised neovascular membranes of patients with diabetes compared with idiopathic epiretinal membranes in nondiabetic patients. Retina (Philadelphia, Pa.). 30: 1472-8. PMID 20811317 DOI: 10.1097/Iae.0B013E3181D6Df09  0.6
2010 Hua J, Spee C, Kase S, Rennel ES, Magnussen AL, Qiu Y, Varey A, Dhayade S, Churchill AJ, Harper SJ, Bates DO, Hinton DR. Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Investigative Ophthalmology & Visual Science. 51: 4282-8. PMID 20237252 DOI: 10.1167/Iovs.09-4360  0.6
2010 Sonoda S, Sreekumar PG, Kase S, Spee C, Ryan SJ, Kannan R, Hinton DR. Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration. Aging. 2: 28-42. PMID 20228934  0.72
2010 Zhou J, He S, Zhang N, Spee C, Zhou P, Ryan SJ, Kannan R, Hinton DR. Neutrophils compromise retinal pigment epithelial barrier integrity. Journal of Biomedicine & Biotechnology. 2010: 289360. PMID 20204129 DOI: 10.1155/2010/289360  0.88
2010 Parra GI, Bergmann CC, Phares TW, Hinton DR, Atkinson R, Stohlman SA. Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection. Journal of Virology. 84: 3111-5. PMID 20042510 DOI: 10.1128/Jvi.02373-09  0.68
2010 Kase S, He S, Sonoda S, Kitamura M, Spee C, Wawrousek E, Ryan SJ, Kannan R, Hinton DR. alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood. 115: 3398-406. PMID 20023214 DOI: 10.1182/Blood-2009-01-197095  0.88
2010 Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death and Differentiation. 17: 488-98. PMID 19816510 DOI: 10.1038/Cdd.2009.144  0.56
2010 Zhu D, Sreekumar PG, Hinton DR, Kannan R. Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration. Vision Research. 50: 643-51. PMID 19765607 DOI: 10.1016/J.Visres.2009.09.002  0.8
2010 Tran ND, Kim S, Vincent HK, Rodriguez A, Hinton DR, Bullock MR, Young HF. Aquaporin-1-mediated cerebral edema following traumatic brain injury: effects of acidosis and corticosteroid administration. Journal of Neurosurgery. 112: 1095-104. PMID 19731985 DOI: 10.3171/2009.8.Jns081704  0.32
2010 He S, Kumar SR, Zhou P, Krasnoperov V, Ryan SJ, Gill PS, Hinton DR. Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. Investigative Ophthalmology & Visual Science. 51: 543-52. PMID 19696168 DOI: 10.1167/Iovs.09-3475  0.88
2010 Chothe PP, Thakkar SV, Gnana-Prakasam JP, Ananth S, Hinton DR, Kannan R, Smith SB, Martin PM, Ganapathy V. Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 51: 413-20. PMID 19643969 DOI: 10.1167/Iovs.09-4048  0.88
2009 Zhu D, Deng X, Xu J, Hinton DR. What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence. Aging. 1: 740-5. PMID 20157553  0.88
2009 Ireland DD, Stohlman SA, Hinton DR, Kapil P, Silverman RH, Atkinson RA, Bergmann CC. RNase L mediated protection from virus induced demyelination. Plos Pathogens. 5: e1000602. PMID 19798426 DOI: 10.1371/Journal.Ppat.1000602  0.68
2009 Sadler TR, Khodavirdi AC, Hinton DR, Holschneider DP. Snap-frozen brain tissue sections stored with desiccant at ambient laboratory conditions without chemical fixation are resistant to degradation for a minimum of 6 months. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 17: 165-71. PMID 19521279 DOI: 10.1097/Pai.0B013E3181853001  0.88
2009 Sonoda S, Spee C, Barron E, Ryan SJ, Kannan R, Hinton DR. A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nature Protocols. 4: 662-73. PMID 19373231 DOI: 10.1038/Nprot.2009.33  0.88
2009 Sreekumar PG, Kannan R, Hinton DR. There are three major families of crystallins: misnaming of alphaB crystallin. Acta Physiologica (Oxford, England). 195: 503; author reply 50. PMID 19291149 DOI: 10.1111/J.1748-1716.2009.01976_1.X  0.6
2009 Kim YH, He S, Kase S, Kitamura M, Ryan SJ, Hinton DR. Regulated secretion of complement factor H by RPE and its role in RPE migration. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 247: 651-9. PMID 19214553 DOI: 10.1007/S00417-009-1049-Y  0.88
2009 Zhu D, Wu J, Spee C, Ryan SJ, Hinton DR. BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. The Journal of Biological Chemistry. 284: 9529-39. PMID 19158083 DOI: 10.1074/Jbc.M809393200  0.88
2009 Ray A, Colodetti L, Weiland JD, Hinton DR, Humayun MS, Lee EJ. Immunocytochemical analysis of retinal neurons under electrical stimulation. Brain Research. 1255: 89-97. PMID 19103179 DOI: 10.1016/J.Brainres.2008.11.089  0.88
2009 Sreekumar PG, Ding Y, Ryan SJ, Kannan R, Hinton DR. Regulation of thioredoxin by ceramide in retinal pigment epithelial cells. Experimental Eye Research. 88: 410-7. PMID 18996115 DOI: 10.1016/J.Exer.2008.10.009  0.88
2009 Hinton DR, Asa SL. Pituitary Modern Surgical Pathology. 2: 1949-1983. DOI: 10.1016/B978-1-4160-3966-2.00050-3  0.88
2008 Savarin C, Bergmann CC, Hinton DR, Ransohoff RM, Stohlman SA. Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis. Journal of Virology. 82: 12432-40. PMID 18842712 DOI: 10.1128/Jvi.01267-08  0.68
2008 Yang Z, Stratton C, Francis PJ, Kleinman ME, Tan PL, Gibbs D, Tong Z, Chen H, Constantine R, Yang X, Chen Y, Zeng J, Davey L, Ma X, Hau VS, ... ... Hinton DR, et al. Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. The New England Journal of Medicine. 359: 1456-63. PMID 18753640 DOI: 10.1056/Nejmoa0802437  0.88
2008 Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS. The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death and Differentiation. 15: 1460-71. PMID 18551133 DOI: 10.1038/Cdd.2008.81  0.56
2008 Lundberg P, Ramakrishna C, Brown J, Tyszka JM, Hamamura M, Hinton DR, Kovats S, Nalcioglu O, Weinberg K, Openshaw H, Cantin EM. The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis. Journal of Virology. 82: 7078-88. PMID 18480436 DOI: 10.1128/Jvi.00619-08  0.4
2008 He S, Chen Y, Khankan R, Barron E, Burton R, Zhu D, Ryan SJ, Oliver N, Hinton DR. Connective tissue growth factor as a mediator of intraocular fibrosis. Investigative Ophthalmology & Visual Science. 49: 4078-88. PMID 18450591 DOI: 10.1167/Iovs.07-1302  0.88
2008 Sreekumar PG, Zhou J, Sohn J, Spee C, Ryan SJ, Maurer BJ, Kannan R, Hinton DR. N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice. Investigative Ophthalmology & Visual Science. 49: 1210-20. PMID 18326751 DOI: 10.1167/Iovs.07-0667  0.88
2008 He S, Yaung J, Kim YH, Barron E, Ryan SJ, Hinton DR. Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 246: 677-83. PMID 18278507 DOI: 10.1007/S00417-008-0770-2  0.88
2008 Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, Hinton DR. Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Experimental Eye Research. 86: 355-65. PMID 18191123 DOI: 10.1016/J.Exer.2007.11.007  0.88
2008 Stohlman SA, Hinton DR, Parra B, Atkinson R, Bergmann CC. CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus. Journal of Virology. 82: 2130-9. PMID 18094171 DOI: 10.1128/Jvi.01762-07  0.68
2008 Ireland DD, Stohlman SA, Hinton DR, Atkinson R, Bergmann CC. Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells. Journal of Virology. 82: 300-10. PMID 17928334 DOI: 10.1128/Jvi.01794-07  0.68
2007 Colodetti L, Weiland JD, Colodetti S, Ray A, Seiler MJ, Hinton DR, Humayun MS. Pathology of damaging electrical stimulation in the retina. Experimental Eye Research. 85: 23-33. PMID 17531974 DOI: 10.1016/J.Exer.2007.02.014  0.88
2007 Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R, Hinton DR. alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Molecular Vision. 13: 566-77. PMID 17438522  0.88
2007 Agrawal RN, He S, Spee C, Cui JZ, Ryan SJ, Hinton DR. In vivo models of proliferative vitreoretinopathy. Nature Protocols. 2: 67-77. PMID 17401340 DOI: 10.1038/Nprot.2007.4  0.88
2007 Tedeschi-Blok N, Buckley J, Varma R, Triche TJ, Hinton DR. Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease. Ophthalmology. 114: 99-103. PMID 17198853 DOI: 10.1016/J.Ophtha.2006.07.043  0.88
2006 He S, Incardona F, Jin M, Ryan SJ, Hinton DR. Thrombospondin-1 expression in RPE and choroidal neovascular membranes. Yan Ke Xue Bao = Eye Science / "Yan Ke Xue Bao" Bian Ji Bu. 22: 265-74. PMID 17378161  0.88
2006 Kannan R, Zhang N, Sreekumar PG, Spee CK, Rodriguez A, Barron E, Hinton DR. Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells. Molecular Vision. 12: 1649-59. PMID 17200665  0.6
2006 Hindinger C, Hinton DR, Kirwin SJ, Atkinson RD, Burnett ME, Bergmann CC, Stohlman SA. Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 84: 1225-34. PMID 16955483 DOI: 10.1002/Jnr.21038  0.68
2006 Kirwin SJ, Dowdell KC, Hindinger C, Feng N, Bergmann CC, Hinton DR, Stohlman SA. Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 178: 30-9. PMID 16814872 DOI: 10.1016/J.Jneuroim.2006.05.015  0.68
2006 Sreekumar PG, Kannan R, de Silva AT, Burton R, Ryan SJ, Hinton DR. Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells. Biochemical and Biophysical Research Communications. 346: 1200-6. PMID 16793007 DOI: 10.1016/J.Bbrc.2006.06.021  0.88
2006 Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, ... ... Hinton DR, et al. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Molecular Vision. 12: 532-80. PMID 16735995  0.88
2006 Kramerov AA, Saghizadeh M, Pan H, Kabosova A, Montenarh M, Ahmed K, Penn JS, Chan CK, Hinton DR, Grant MB, Ljubimov AV. Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. The American Journal of Pathology. 168: 1722-36. PMID 16651637 DOI: 10.2353/Ajpath.2006.050533  0.88
2006 Hoffmann S, He S, Ehren M, Ryan SJ, Wiedemann P, Hinton DR. MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes. Retina (Philadelphia, Pa.). 26: 454-61. PMID 16603966 DOI: 10.1097/01.Iae.0000238549.74626.33  0.88
2006 Gamulescu MA, Chen Y, He S, Spee C, Jin M, Ryan SJ, Hinton DR. Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor. Experimental Eye Research. 83: 212-22. PMID 16563380 DOI: 10.1016/J.Exer.2005.12.007  0.88
2006 Zuo J, Stohlman SA, Hoskin JB, Hinton DR, Atkinson R, Bergmann CC. Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells. Virology. 350: 206-15. PMID 16510164 DOI: 10.1016/J.Virol.2006.01.027  0.68
2006 González JM, Bergmann CC, Ramakrishna C, Hinton DR, Atkinson R, Hoskin J, Macklin WB, Stohlman SA. Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination. The American Journal of Pathology. 168: 796-804. PMID 16507895 DOI: 10.2353/Ajpath.2006.050496  0.68
2006 Tschen SI, Stohlman SA, Ramakrishna C, Hinton DR, Atkinson RD, Bergmann CC. CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS. European Journal of Immunology. 36: 603-12. PMID 16437540 DOI: 10.1002/Eji.200535123  0.68
2006 Campochiaro PA, Alani R, Alitalo K, Brooks P, Caldwell R, Carmeliet P, Claudio PP, D'Amato R, Das A, De Martin R, Detmar M, Ferrara N, Frank RN, Fruttiger M, Giordano A, ... ... Hinton D, et al. Ocular versus extraocular neovascularization: Mirror images or vague resemblances Investigative Ophthalmology and Visual Science. 47: 462-474. PMID 16431938 DOI: 10.1167/Iovs.05-1494  0.88
2006 Zhang N, Kannan R, Okamoto CT, Ryan SJ, Lee VH, Hinton DR. Characterization of brimonidine transport in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 47: 287-94. PMID 16384975 DOI: 10.1167/Iovs.05-0189  0.88
2006 Hangai M, He S, Hoffmann S, Lim JI, Ryan SJ, Hinton DR. Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells. Journal of Neuroimmunology. 171: 45-56. PMID 16288810 DOI: 10.1016/J.Jneuroim.2005.09.018  0.88
2005 Lim JI, Spee C, Hangai M, Rocha J, Ying HS, Ryan SJ, Hinton DR. Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes. American Journal of Ophthalmology. 140: 1044-1050. PMID 16376649 DOI: 10.1016/J.Ajo.2005.07.021  0.88
2005 He S, Ding Y, Zhou J, Krasnoperov V, Zozulya S, Kumar SR, Ryan SJ, Gill PS, Hinton DR. Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 46: 4772-9. PMID 16303978 DOI: 10.1167/Iovs.05-0502  0.88
2005 Jin M, Yaung J, Kannan R, He S, Ryan SJ, Hinton DR. Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion. Investigative Ophthalmology & Visual Science. 46: 4311-9. PMID 16249513 DOI: 10.1167/Iovs.05-0353  0.88
2005 Pan J, Al-Dubaib M, Liao CP, Fujino Y, Hinton DR, Hayes KA, Mathes LE, Roy-Burman P. In vivo expression of GFP transgene delivered via a replicating feline leukemia virus. Veterinary Microbiology. 110: 181-95. PMID 16143471 DOI: 10.1016/J.Vetmic.2005.07.015  0.88
2005 Hindinger C, Gonzalez JM, Bergmann CC, Fuss B, Hinton DR, Atkinson RD, Macklin WB, Stohlman SA. Astrocyte expression of a dominant-negative interferon-gamma receptor. Journal of Neuroscience Research. 82: 20-31. PMID 16118798 DOI: 10.1002/Jnr.20616  0.88
2005 Sreekumar PG, Kannan R, Yaung J, Spee CK, Ryan SJ, Hinton DR. Protection from oxidative stress by methionine sulfoxide reductases in RPE cells. Biochemical and Biophysical Research Communications. 334: 245-53. PMID 15993845 DOI: 10.1016/J.Bbrc.2005.06.081  0.88
2005 Zhou J, Pham L, Zhang N, He S, Gamulescu MA, Spee C, Ryan SJ, Hinton DR. Neutrophils promote experimental choroidal neovascularization. Molecular Vision. 11: 414-24. PMID 15988410  0.88
2005 Hoffmann S, He S, Jin M, Ehren M, Wiedemann P, Ryan SJ, Hinton DR. A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion. Bmc Ophthalmology. 5: 16. PMID 15987521 DOI: 10.1186/1471-2415-5-16  0.88
2005 Güven D, Weiland JD, Fujii G, Mech BV, Mahadevappa M, Greenberg R, Roizenblatt R, Qiu G, Labree L, Wang X, Hinton D, Humayun MS. Long-term stimulation by active epiretinal implants in normal and RCD1 dogs. Journal of Neural Engineering. 2: S65-73. PMID 15876657 DOI: 10.1088/1741-2560/2/1/009  0.88
2005 Chan CK, Pham LN, Zhou J, Spee C, Ryan SJ, Hinton DR. Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 721-33. PMID 15856049 DOI: 10.1038/Labinvest.3700277  0.88
2005 Zhou J, Hinton DR, Stohlman SA, Liu CP, Zhong L, Marten NW. Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2. Viral Immunology. 18: 162-9. PMID 15802960 DOI: 10.1089/Vim.2005.18.162  0.88
2005 Zhou J, Marten NW, Bergmann CC, Macklin WB, Hinton DR, Stohlman SA. Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. Journal of Virology. 79: 4764-73. PMID 15795262 DOI: 10.1128/Jvi.79.8.4764-4773.2005  0.88
2005 González JM, Bergmann CC, Fuss B, Hinton DR, Kangas C, Macklin WB, Stohlman SA. Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes. Glia. 51: 22-34. PMID 15779088 DOI: 10.1002/Glia.20182  0.88
2005 Ryan SJ, Hinton DR, Murata T. Choroidal Neovascularization Retina: Fourth Edition. 2: 991-1009. DOI: 10.1016/B978-0-323-02598-0.50062-8  0.88
2004 Ramakrishna C, Stohlman SA, Atkinson RA, Hinton DR, Bergmann CC. Differential regulation of primary and secondary CD8+ T cells in the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 173: 6265-73. PMID 15528365 DOI: 10.4049/Jimmunol.173.10.6265  0.68
2004 Kannan R, Jin M, Gamulescu MA, Hinton DR. Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor. Free Radical Biology & Medicine. 37: 166-75. PMID 15203188 DOI: 10.1016/J.Freeradbiomed.2004.04.011  0.88
2004 Weiner LP, Louie KA, Atalla LR, Kochounian HH, Du J, Wei W, Hinton DR, Gordon EM, Anderson WF, McMillan M. Gene therapy in a murine model for clinical application to multiple sclerosis. Annals of Neurology. 55: 390-9. PMID 14991817 DOI: 10.1002/Ana.10858  0.88
2004 Hinton DR, Spee C, He S, Weitz S, Usinger W, LaBree L, Oliver N, Lim JI. Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy. Diabetes Care. 27: 758-64. PMID 14988298 DOI: 10.2337/Diacare.27.3.758  0.88
2004 Bergmann CC, Parra B, Hinton DR, Ramakrishna C, Dowdell KC, Stohlman SA. Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells. Journal of Virology. 78: 1739-50. PMID 14747539 DOI: 10.1128/Jvi.78.4.1739-1750.2004  0.68
2004 Chan CK, Pham LN, Chinn C, Spee C, Ryan SJ, Akhurst RJ, Hinton DR. Mouse strain-dependent heterogeneity of resting limbal vasculature. Investigative Ophthalmology & Visual Science. 45: 441-7. PMID 14744883 DOI: 10.1167/Iovs.03-0869  0.88
2004 Jin M, Chen Y, He S, Ryan SJ, Hinton DR. Hepatocyte growth factor and its role in the pathogenesis of retinal detachment. Investigative Ophthalmology & Visual Science. 45: 323-9. PMID 14691191 DOI: 10.1167/Iovs.03-0355  0.88
2003 Karanjawala ZE, Hinton DR, Oh E, Hsieh CL, Lieber MR. Developmental retinal apoptosis in Ku86-/- mice. Dna Repair. 2: 1429-34. PMID 14642570 DOI: 10.1016/J.Dnarep.2003.08.011  0.32
2003 He S, Jin ML, Worpel V, Hinton DR. A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 1283-8. PMID 12963611 DOI: 10.1001/Archopht.121.9.1283  0.88
2003 Wu LY, Li M, Hinton DR, Guo L, Jiang S, Wang JT, Zeng A, Xie JB, Snead M, Shuler C, Maxson RE, Liu YH. Microphthalmia resulting from MSX2-induced apoptosis in the optic vesicle. Investigative Ophthalmology & Visual Science. 44: 2404-12. PMID 12766037 DOI: 10.1167/Iovs.02-0317  0.88
2003 Zhou J, Stohlman SA, Hinton DR, Marten NW. Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 170: 3331-6. PMID 12626593 DOI: 10.4049/Jimmunol.170.6.3331  0.88
2003 Bergmann CC, Parra B, Hinton DR, Chandran R, Morrison M, Stohlman SA. Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC up-regulation. Journal of Immunology (Baltimore, Md. : 1950). 170: 3204-13. PMID 12626579 DOI: 10.4049/Jimmunol.170.6.3204  0.68
2002 Stohlman SA, Ramakrishna C, Tschen SI, Hinton DR, Bergmann CC. The art of survival during viral persistence. Journal of Neurovirology. 8: 53-8. PMID 12491152 DOI: 10.1080/13550280290167884  0.68
2002 Simard M, Zhang W, Hinton DR, Chen TC, Weiss MH, Su YZ, Gopalakrishna R, Law RE, Couldwell WT. Tamoxifen-induced growth arrest and apoptosis in pituitary tumor cells in vitro via a protein kinase C-independent pathway. Cancer Letters. 185: 131-8. PMID 12169386 DOI: 10.1016/S0304-3835(02)00261-6  0.88
2002 Jin M, Barron E, He S, Ryan SJ, Hinton DR. Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor. Investigative Ophthalmology & Visual Science. 43: 2782-90. PMID 12147616  0.88
2002 Hinton DR, He S, Jin ML, Barron E, Ryan SJ. Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy. Eye (London, England). 16: 422-8. PMID 12101449 DOI: 10.1038/Sj.Eye.6700190  0.88
2002 Zhou J, Stohlman SA, Atkinson R, Hinton DR, Marten NW. Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection. Journal of Virology. 76: 7374-84. PMID 12097550 DOI: 10.1128/Jvi.76.15.7374-7384.2002  0.88
2002 Karanjawala ZE, Murphy N, Hinton DR, Hsieh CL, Lieber MR. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Current Biology : Cb. 12: 397-402. PMID 11882291 DOI: 10.1016/S0960-9822(02)00684-X  0.32
2002 Ryan SJ, Hinton DR, Ogden TE, Rao N. Translational research in ophthalmology. Archives of Ophthalmology. 120: 389-90. PMID 11879146 DOI: 10.1001/Archopht.120.3.389  0.88
2001 Marten NW, Hohman M, Stohlman SA, Atkinson RD, Hinton DR, Bergmann CC. Acute CNS infection is insufficient to mediate chronic T cell retention. Advances in Experimental Medicine and Biology. 494: 349-54. PMID 11774491 DOI: 10.1007/978-1-4615-1325-4_52  0.88
2001 Parra B, Bergmann CC, Hinton DR, Atkinson R, Stohlman SA. IFN-gamma secreted by virus-specific CD8+ T cells contribute to CNS viral clearance. Advances in Experimental Medicine and Biology. 494: 335-40. PMID 11774489 DOI: 10.1007/978-1-4615-1325-4_50  0.68
2001 Zhou J, Stohlman SA, Marten NW, Hinton DR. Regulation of matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) genes during JHMV infection of the central nervous system. Advances in Experimental Medicine and Biology. 494: 329-34. PMID 11774488 DOI: 10.1007/978-1-4615-1325-4_49  0.88
2001 Bergmann CC, Marten NW, Hinton DR, Parra B, Stohlman SA. CD8 T cell mediated immunity to neurotropic MHV infection. Advances in Experimental Medicine and Biology. 494: 299-308. PMID 11774484 DOI: 10.1007/978-1-4615-1325-4_46  0.68
2001 Qiao H, Sakamoto T, Hinton DR, Gopalakrishna R, Ishibashi T, Ryan SJ, Inomata H. Interferon beta affects retinal pigment epithelial cell proliferation via protein kinase C pathways. Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift FüR Augenheilkunde. 215: 401-7. PMID 11741104 DOI: 10.1159/000050897  0.88
2001 Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood. 98: 1904-13. PMID 11535528 DOI: 10.1182/Blood.V98.6.1904  0.4
2001 Hangai M, Moon YS, Kitaya N, Chan CK, Wu DY, Peters KG, Ryan SJ, Hinton DR. Systemically expressed soluble Tie2 inhibits intraocular neovascularization. Human Gene Therapy. 12: 1311-21. PMID 11440624 DOI: 10.1089/104303401750270968  0.88
2001 Hangai M, Murata T, Miyawaki N, Spee C, Lim JI, He S, Hinton DR, Ryan SJ. Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 42: 1617-25. PMID 11381069  0.88
2001 Murata T, Hata Y, Ishibashi T, Kim S, Hsueh WA, Law RE, Hinton DR. Response of experimental retinal neovascularization to thiazolidinediones. Archives of Ophthalmology (Chicago, Ill. : 1960). 119: 709-17. PMID 11346398 DOI: 10.1001/Archopht.119.5.709  0.36
2001 Gordon EM, Chen ZH, Liu L, Whitley M, Liu L, Wei D, Groshen S, Hinton DR, Anderson WF, Beart RW, Hall FL. Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice. Human Gene Therapy. 12: 193-204. PMID 11177556 DOI: 10.1089/104303401750061258  0.88
2001 Stohlman SA, Hinton DR. Viral induced demyelination. Brain Pathology (Zurich, Switzerland). 11: 92-106. PMID 11145206 DOI: 10.1111/J.1750-3639.2001.Tb00384.X  0.68
2001 Iveković R, Mandić Z, Sarić D, Sonicki Z, Pozzo SD, Parodi MB, Toto L, Ravalico G, Grus FH, Dick B, Augustin AJ, Pfeiffer N, Qiao H, Sakamoto T, Hinton DR, et al. Contents Vol. 215, 2001 Ophthalmologica. 215: 453-456. DOI: 10.1159/000050910  0.72
2001 Iveković R, Mandić Z, Sarić D, Sonicki Z, Pozzo SD, Parodi MB, Toto L, Ravalico G, Grus FH, Dick B, Augustin AJ, Pfeiffer N, Qiao H, Sakamoto T, Hinton DR, et al. Subject Index Vol. 215, 2001 Ophthalmologica. 215: 451-452. DOI: 10.1159/000050909  0.72
2000 Cai J, Zheng T, Masood R, Smith DL, Hinton DR, Kim CN, Fang G, Bhalla K, Gill PS. Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells. Sarcoma. 4: 37-45. PMID 18521433 DOI: 10.1155/S1357714X00000074  0.4
2000 Jin M, He S, Wörpel V, Ryan SJ, Hinton DR. Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha. Investigative Ophthalmology & Visual Science. 41: 4324-32. PMID 11095634  0.88
2000 Gordon EM, Liu PX, Chen ZH, Liu L, Whitley MD, Gee C, Groshen S, Hinton DR, Beart RW, Hall FL. Inhibition of metastatic tumor growth in nude mice by portal vein infusions of matrix-targeted retroviral vectors bearing a cytocidal cyclin G1 construct. Cancer Research. 60: 3343-7. PMID 10910035  0.88
2000 Hoffmann S, Masood R, Zhang Y, He S, Ryan SJ, Gill P, Hinton DR. Selective killing of RPE with a vascular endothelial growth factor chimeric toxin. Investigative Ophthalmology & Visual Science. 41: 2389-93. PMID 10892888  0.88
2000 Murata T, He S, Hangai M, Ishibashi T, Xi XP, Kim S, Hsueh WA, Ryan SJ, Law RE, Hinton DR. Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization. Investigative Ophthalmology & Visual Science. 41: 2309-17. PMID 10892878  0.88
2000 Murata T, Cui J, Taba KE, Oh JY, Spee C, Hinton DR, Ryan SJ. The possibility of gene therapy for the treatment of choroidal neovascularization. Ophthalmology. 107: 1364-73. PMID 10889114 DOI: 10.1016/S0161-6420(00)00147-0  0.88
2000 Cui JZ, Kimura H, Spee C, Thumann G, Hinton DR, Ryan SJ. Natural history of choroidal neovascularization induced by vascular endothelial growth factor in the primate. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 238: 326-33. PMID 10853932 DOI: 10.1007/S004170050360  0.88
2000 Marten NW, Stohlman SA, Atkinson RD, Hinton DR, Fleming JO, Bergmann CC. Contributions of CD8+ T cells and viral spread to demyelinating disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 4080-8. PMID 10754301 DOI: 10.4049/Jimmunol.164.8.4080  0.68
2000 Parra B, Lin MT, Stohlman SA, Bergmann CC, Atkinson R, Hinton DR. Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system. Journal of Virology. 74: 2447-50. PMID 10666278 DOI: 10.1128/Jvi.74.5.2447-2450.2000  0.68
1999 Albuquerque FC, Weiss MH, Kovacs K, Horvath E, Sasano H, Hinton DR. A functioning composite 'corticotroph' pituitary adenoma with interspersed adrenocortical cells. Pituitary. 1: 279-84. PMID 11081209 DOI: 10.1023/A:1009962627216  0.32
1999 Amar AP, Hinton DR, Krieger MD, Weiss MH. Invasive pituitary adenomas: significance of proliferation parameters. Pituitary. 2: 117-22. PMID 11081161 DOI: 10.1023/A:1009931413106  0.32
1999 Stohlman SA, Pei L, Cua DJ, Li Z, Hinton DR. Activation of regulatory cells suppresses experimental allergic encephalomyelitis via secretion of IL-10. Journal of Immunology (Baltimore, Md. : 1950). 163: 6338-44. PMID 10570329  0.68
1999 Tahara YR, Sakamoto TR, Oshima YR, Ishibashi TR, Inomata HR, Murata TR, Hinton DR, Ryan SJ. The antidepressant hypericin inhibits progression of experimental proliferative vitreoretinopathy. Current Eye Research. 19: 323-9. PMID 10520228 DOI: 10.1076/Ceyr.19.4.323.5302  0.88
1999 Zhao MW, Jin ML, He S, Spee C, Ryan SJ, Hinton DR. A distinct integrin-mediated phagocytic pathway for extracellular matrix remodeling by RPE cells. Investigative Ophthalmology & Visual Science. 40: 2713-23. PMID 10509670  0.88
1999 Thumann G, Bartz-Schmidt KU, El Bakri H, Schraermeyer U, Spee C, Cui JZ, Hinton DR, Ryan SJ, Heimann K. Transplantation of autologous iris pigment epithelium to the subretinal space in rabbits. Transplantation. 68: 195-201. PMID 10440387 DOI: 10.1097/00007890-199907270-00006  0.88
1999 Kundu RK, Sangiorgi F, Wu LY, Pattengale PK, Hinton DR, Gill PS, Maxson R. Expression of the human immunodeficiency virus-Tat gene in lymphoid tissues of transgenic mice is associated with B-cell lymphoma. Blood. 94: 275-82. PMID 10381523 DOI: 10.1182/Blood.V94.1.275.413A30_275_282  0.4
1999 Hofman FM, Chen P, Incardona F, Zidovetzki R, Hinton DR. HIV-1 tat protein induces the production of interleukin-8 by human brain-derived endothelial cells. Journal of Neuroimmunology. 94: 28-39. PMID 10376933 DOI: 10.1016/S0165-5728(98)00198-2  0.36
1999 Lin MT, Hinton DR, Marten NW, Bergmann CC, Stohlman SA. Antibody prevents virus reactivation within the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 162: 7358-68. PMID 10358187  0.68
1999 Casella AM, Taba KE, Kimura H, Spee C, Cardillo JA, Ryan SJ, Hinton DR. Retinal pigment epithelial cells are heterogeneous in their expression of MHC-II after stimulation with interferon-gamma. Experimental Eye Research. 68: 423-30. PMID 10192799 DOI: 10.1006/Exer.1998.0621  0.88
1999 Cua DJ, Groux H, Hinton DR, Stohlman SA, Coffman RL. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 189: 1005-10. PMID 10075984 DOI: 10.1084/Jem.189.6.1005  0.68
1999 Parra B, Hinton DR, Marten NW, Bergmann CC, Lin MT, Yang CS, Stohlman SA. IFN-gamma is required for viral clearance from central nervous system oligodendroglia. Journal of Immunology (Baltimore, Md. : 1950). 162: 1641-7. PMID 9973424  0.68
1999 Kimura H, Spee C, Sakamoto T, Hinton DR, Ogura Y, Tabata Y, Ikada Y, Ryan SJ. Cellular response in subretinal neovascularization induced by bFGF-impregnated microspheres. Investigative Ophthalmology & Visual Science. 40: 524-8. PMID 9950614  0.88
1999 Mendel E, Khoo LT, Go JL, Hinton D, Zee CS, Apuzzo ML. Intracerebral Whipple's disease diagnosed by stereotactic biopsy: a case report and review of the literature. Neurosurgery. 44: 203-9. PMID 9894983 DOI: 10.1097/00006123-199901000-00123  0.88
1998 Ishibashi T, Murata T, Hangai M, Nagai R, Horiuchi S, Lopez PF, Hinton DR, Ryan SJ. Advanced glycation end products in age-related macular degeneration. Archives of Ophthalmology. 116: 1629-32. PMID 9869793 DOI: 10.1001/Archopht.116.12.1629  0.88
1998 Albuquerque FC, Hinton DR, Weiss MH. Excessively high prolactin level in a patient with a nonprolactin-secreting adenoma. Case report. Journal of Neurosurgery. 89: 1043-6. PMID 9833836 DOI: 10.3171/Jns.1998.89.6.1043  0.32
1998 Murata T, Hangai M, Ishibashi T, Spee C, Gordon EM, Anderson WF, Hinton DR, Ryan SJ. Retrovirus-mediated gene transfer to photocoagulation-induced choroidal neovascular membranes. Investigative Ophthalmology & Visual Science. 39: 2474-8. PMID 9804157  0.88
1998 Hoffmann S, Spee C, Murata T, Cui JZ, Ryan SJ, Hinton DR. Rapid isolation of choriocapillary endothelial cells by Lycopersicon esculentum-coated Dynabeads. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 236: 779-84. PMID 9801894 DOI: 10.1007/S004170050158  0.88
1998 Zhang X, Hinten D, Park S, Liao CL, Lai MMC, Stohlman S. Using a defective-interfering RNA system to express the HE protein of mouse hepatitis virus for studying viral pathogenesis Advances in Experimental Medicine and Biology. 440: 521-528. PMID 9782324 DOI: 10.1007/978-1-4615-5331-1_67  0.4
1998 Lin MT, Hinton DR, Stohlman SA. Mechanisms of viral clearance in perforin-deficient mice. Advances in Experimental Medicine and Biology. 440: 431-6. PMID 9782311 DOI: 10.1007/978-1-4615-5331-1_54  0.68
1998 Stohlman SA, Bergmann CC, Cua DJ, Lin MT, Ho S, Wei W, Hinton DR. Apoptosis of JHMV-specific CTL in the CNS in the absence of CD4+ T cells. Advances in Experimental Medicine and Biology. 440: 425-30. PMID 9782310 DOI: 10.1007/978-1-4615-5331-1_53  0.68
1998 He PM, He S, Garner JA, Ryan SJ, Hinton DR. Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor. Biochemical and Biophysical Research Communications. 249: 253-7. PMID 9705867 DOI: 10.1006/Bbrc.1998.9087  0.88
1998 Hoffman S, Gopalakrishna R, Gundimeda U, Murata T, Spee C, Ryan SJ, Hinton DR. Verapamil inhibits proliferation, migration and protein kinase C activity in human retinal pigment epithelial cells. Experimental Eye Research. 67: 45-52. PMID 9702177 DOI: 10.1006/Exer.1998.0491  0.88
1998 Lin MT, Hinton DR, Parra B, Stohlman SA, van der Veen RC. The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis. Virology. 245: 270-80. PMID 9636366 DOI: 10.1006/Viro.1998.9170  0.68
1998 Murata T, Hoffmann S, Ishibashi T, Spee C, Gordon EM, Anderson WF, Hinton DR, Ryan SJ. Retrovirus-mediated gene transfer targeted to retinal photocoagulation sites. Diabetologia. 41: 500-6. PMID 9628265 DOI: 10.1007/S001250050938  0.88
1998 Hinton DR, Hahn JA, Weiss MH, Couldwell WT. Loss of Rb expression in an ACTH-secreting pituitary carcinoma. Cancer Letters. 126: 209-14. PMID 9585068 DOI: 10.1016/S0304-3835(98)00013-5  0.88
1998 Sakamoto T, Spee C, Scuric Z, Gordon EM, Hinton DR, Anderson WF, Ryan SJ. Ability of retroviral transduction to modify the angiogenic characteristics of RPE cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 236: 220-9. PMID 9541827 DOI: 10.1007/S004170050068  0.88
1998 Hinton DR, He S, Graf K, Yang D, Hsueh WA, Ryan SJ, Law RE. Mitogen-activated protein kinase activation mediates PDGF-directed migration of RPE cells. Experimental Cell Research. 239: 11-5. PMID 9511719 DOI: 10.1006/Excr.1997.3873  0.88
1998 Stohlman SA, Bergmann CC, Lin MT, Cua DJ, Hinton DR. CTL effector function within the central nervous system requires CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 160: 2896-904. PMID 9510193  0.68
1998 Shimon I, Hinton DR, Weiss MH, Melmed S. Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness. Clinical Endocrinology. 48: 23-9. PMID 9509064 DOI: 10.1046/J.1365-2265.1998.00332.X  0.32
1998 Zhang X, Hinton DR, Park S, Parra B, Liao CL, Lai MM, Stohlman SA. Expression of hemagglutinin/esterase by a mouse hepatitis virus coronavirus defective-interfering RNA alters viral pathogenesis. Virology. 242: 170-83. PMID 9501044 DOI: 10.1006/Viro.1997.8993  0.68
1998 Hinton DR, He S, Lopez PF. Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 116: 203-9. PMID 9488273 DOI: 10.1001/Archopht.116.2.203  0.88
1998 Chen TC, Hinton DR, Zidovetzki R, Hofman FM. Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. Laboratory Investigation; a Journal of Technical Methods and Pathology. 78: 165-74. PMID 9484714  0.32
1997 Lefkowitz MA, Hinton DR, Weiss MH, Giannotta SL, Couldwell WT. Prognostic variables in surgery for skull base meningiomas. Neurosurgical Focus. 2: e2. PMID 15096006 DOI: 10.3171/Foc.1997.2.4.5  0.36
1997 Zhang W, Law RE, Hinton DR, Couldwell WT. Inhibition of human malignant glioma cell motility and invasion in vitro by hypericin, a potent protein kinase C inhibitor. Cancer Letters. 120: 31-8. PMID 9570383 DOI: 10.1016/S0304-3835(97)00287-5  0.36
1997 Kimura H, Harris MS, Sakamoto T, Gopalakrishna R, Gundimeda U, Cui JZ, Spee C, Hinton DR, Ryan SJ. Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro. Current Eye Research. 16: 967-72. PMID 9330847 DOI: 10.1076/Ceyr.16.10.967.9019  0.88
1997 Murata T, Kimura H, Sakamoto T, Osusky R, Spee C, Stout TJ, Hinton DR, Ryan SJ. Ocular gene therapy: experimental studies and clinical possibilities. Ophthalmic Research. 29: 242-51. PMID 9323715 DOI: 10.1159/000268022  0.88
1997 Cloughesy TF, Woods RP, Black KL, Couldwell WT, Law RE, Hinton DR. Prolonged treatment with biologic agents for malignant glioma: a case study with high dose tamoxifen. Journal of Neuro-Oncology. 35: 39-45. PMID 9266439 DOI: 10.1023/A:1005895616377  0.36
1997 Cardillo JA, Stout JT, LaBree L, Azen SP, Omphroy L, Cui JZ, Kimura H, Hinton DR, Ryan SJ. Post-traumatic proliferative vitreoretinopathy. The epidemiologic profile, onset, risk factors, and visual outcome. Ophthalmology. 104: 1166-73. PMID 9224471 DOI: 10.1016/S0161-6420(97)30167-5  0.88
1997 Schubert CA, Kimura H, Spee C, Hinton DR, Gordon EM, Anderson WF, Ryan SJ. Retrovirus-mediated transfer of the suicide gene into retinal pigment epithelial cells in vitro. Current Eye Research. 16: 656-62. PMID 9222082 DOI: 10.1076/ceyr.16.7.656.5066  0.88
1997 Zhang X, Hinton DR, Cua DJ, Stohlman SA, Lai MM. Expression of interferon-gamma by a coronavirus defective-interfering RNA vector and its effect on viral replication, spread, and pathogenicity. Virology. 233: 327-38. PMID 9217056 DOI: 10.1006/Viro.1997.8598  0.68
1997 Parra B, Hinton DR, Lin MT, Cua DJ, Stohlman SA. Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis. Virology. 233: 260-70. PMID 9217050 DOI: 10.1006/Viro.1997.8613  0.68
1997 van der Veen RC, Hinton DR, Incardonna F, Hofman FM. Extensive peroxynitrite activity during progressive stages of central nervous system inflammation. Journal of Neuroimmunology. 77: 1-7. PMID 9209262 DOI: 10.1016/S0165-5728(97)00013-1  0.32
1997 Stohlman SA, Lin M, Parra B, Bergmann CC, Hinton DR. Immune regulation of coronavirus-induced demyelinating encephalomyelitis. Journal of Neurovirology. 3: S56-7. PMID 9179796  0.68
1997 Chen TC, Hinton DR, Sippy BD, Hofman FM. Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas. Journal of Neuropathology and Experimental Neurology. 56: 541-50. PMID 9143267 DOI: 10.1097/00005072-199705000-00010  0.32
1997 Chen TC, Hinton DR, Yong VW, Hofman FM. TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells. Journal of Neuroimmunology. 73: 155-61. PMID 9058771 DOI: 10.1016/S0165-5728(96)00190-7  0.88
1997 Yoo JS, Sakamoto T, Spee C, Kimura H, Harris MS, Hinton DR, Kay EP, Ryan SJ. cis-Hydroxyproline inhibits proliferation, collagen synthesis, attachment, and migration of cultured bovine retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 38: 520-8. PMID 9040485  0.88
1997 Hinton DR, Polk RK, Linse KD, Weiss MH, Kovacs K, Garner JA. Characterization of spherical amyloid protein from a prolactin-producing pituitary adenoma. Acta Neuropathologica. 93: 43-9. PMID 9006656 DOI: 10.1097/00005072-199605000-00194  0.88
1997 Lin MT, Stohlman SA, Hinton DR. Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis. Journal of Virology. 71: 383-91. PMID 8985361 DOI: 10.1128/Jvi.71.1.383-391.1997  0.68
1996 Couldwell WT, Stillerman CB, Rice D, Maceri D, Sherman R, Fukushima T, Hinton DR. Malignant clival chordoma with postoperative cutaneous metastases. Skull Base Surgery. 6: 61-6. PMID 17170954 DOI: 10.1055/S-2008-1058914  0.36
1996 Zhang W, Anker L, Law RE, Hinton DR, Gopalakrishna R, Pu Q, Gundimeda U, Weiss MH, Couldwell WT. Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 2: 843-6. PMID 9816239  0.88
1996 Couldwell WT, Hinton DR, Surnock AA, DeGiorgio CM, Weiner LP, Apuzzo ML, Masri L, Law RE, Weiss MH. Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 2: 619-22. PMID 9816211  0.36
1996 Soong NW, Dang MH, Hinton DR, Arnheim N. Mitochondrial DNA deletions are rare in the free radical-rich retinal environment. Neurobiology of Aging. 17: 827-31. PMID 9363792 DOI: 10.1016/S0197-4580(96)00163-7  0.88
1996 Openshaw H, Slatkin NE, Stein AS, Hinton DR, Forman SJ. Acute polyneuropathy after high dose cytosine arabinoside in patients with leukemia. Cancer. 78: 1899-905. PMID 8909309 DOI: 10.1002/(SICI)1097-0142(19961101)78:9<1899::AID-CNCR9>3.0.CO;2-A  0.4
1996 Kovacs A, Hinton DR, Wright D, Xu J, Li XL, Rasheed S, Hofman F. Human immunodeficiency virus type 1 infection of the heart in three infants with acquired immunodeficiency syndrome and sudden death. The Pediatric Infectious Disease Journal. 15: 819-24. PMID 8878228 DOI: 10.1097/00006454-199609000-00017  0.8
1996 Kimura H, Sakamoto T, Cardillo JA, Spee C, Hinton DR, Gordon EM, Anderson WF, Ryan SJ. Retrovirus-mediated suicide gene transduction in the vitreous cavity of the eye: feasibility in prevention of proliferative vitreoretinopathy. Human Gene Therapy. 7: 799-808. PMID 8860832 DOI: 10.1089/Hum.1996.7.7-799  0.88
1996 Zhang W, Hinton DR, Surnock AA, Couldwell WT. Malignant glioma sensitivity to radiotherapy, high-dose tamoxifen, and hypericin: corroborating clinical response in vitro: case report. Neurosurgery. 38: 587-90; discussion 5. PMID 8837815 DOI: 10.1097/00006123-199603000-00035  0.36
1996 Hamilton HB, Hinton DR, Law RE, Gopalakrishna R, Su YZ, Chen ZH, Weiss MH, Couldwell WT. Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application. Journal of Neurosurgery. 85: 329-34. PMID 8755764 DOI: 10.3171/Jns.1996.85.2.0329  0.88
1996 Couldwell WT, Law RE, Hinton DR, Gopalakrishna R, Yong VW, Weiss MH. Protein kinase C and growth regulation of pituitary adenomas. Acta Neurochirurgica. Supplement. 65: 22-6. PMID 8738488 DOI: 10.1007/978-3-7091-9450-8_8  0.88
1996 Blanks JC, Schmidt SY, Torigoe Y, Porrello KV, Hinton DR, Blanks RH. Retinal pathology in Alzheimer's disease. II. Regional neuron loss and glial changes in GCL. Neurobiology of Aging. 17: 385-95. PMID 8725900 DOI: 10.1016/0197-4580(96)00009-7  0.88
1996 Blanks JC, Torigoe Y, Hinton DR, Blanks RH. Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina. Neurobiology of Aging. 17: 377-84. PMID 8725899 DOI: 10.1016/0197-4580(96)00010-3  0.88
1996 Sakamoto T, Hinton DR, Kimura H, Spee C, Gopalakrishna R, Ryan SJ. Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 234: 186-92. PMID 8720718 DOI: 10.1007/Bf00462031  0.88
1996 Harris MS, Sakamoto T, Kimura H, He S, Spee C, Gopalakrishna R, Gundimeda U, Yoo JS, Hinton DR, Ryan SJ. Hypericin inhibits cell growth and induces apoptosis in retinal pigment epithelial cells: possible involvement of protein kinase C. Current Eye Research. 15: 255-62. PMID 8654105 DOI: 10.3109/02713689609007619  0.88
1996 Lopez PF, Sippy BD, Lambert HM, Thach AB, Hinton DR. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Investigative Ophthalmology & Visual Science. 37: 855-68. PMID 8603870 DOI: 10.1097/00006982-199805000-00035  0.32
1996 Sippy BD, Hofman FM, Wright AD, Wang JL, Gopalakrishna R, Gundimeda U, He S, Ryan SJ, Hinton DR. Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 37: 597-606. PMID 8595959  0.88
1995 Sakamoto T, Kimura H, Scuric Z, Spee C, Gordon EM, Hinton DR, Anderson WF, Ryan SJ. Inhibition of experimental proliferative vitreoretinopathy by retroviral vector-mediated transfer of suicide gene. Can proliferative vitreoretinopathy be a target of gene therapy? Ophthalmology. 102: 1417-24. PMID 9097787 DOI: 10.1016/S0161-6420(95)30850-0  0.88
1995 Stohlman SA, Yao Q, Bergmann CC, Tahara SM, Kyuwa S, Hinton DR. Transcription and translation of proinflammatory cytokines following JHMV infection. Advances in Experimental Medicine and Biology. 380: 173-8. PMID 8830475 DOI: 10.1007/978-1-4615-1899-0_28  0.68
1995 Sippy BD, Hofman FM, Wallach D, Hinton DR. Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 10: 511-21. PMID 8548330 DOI: 10.1097/00042560-199510050-00004  0.32
1995 Sakamoto T, Sakamoto H, Hinton DR, Spee C, Ishibashi T, Ryan SJ. In vitro studies of human choroidal endothelial cells. Current Eye Research. 14: 621-7. PMID 8529396 DOI: 10.3109/02713689508998488  0.72
1995 Tishler DM, Weinberg KI, Hinton DR, Barbaro N, Annett GM, Raffel C. MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia. 36: 1-6. PMID 8001500 DOI: 10.1111/J.1528-1157.1995.Tb01657.X  0.88
1995 Sakamoto T, Soriano D, Nassaralla J, Murphy TL, Oganesian A, Spee C, Hinton DR, Ryan SJ. Effect of intravitreal administration of indomethacin on experimental subretinal neovascularization in the subhuman primate. Archives of Ophthalmology. 113: 222-6. PMID 7864756 DOI: 10.1001/Archopht.1995.01100020106040  0.72
1995 Couldwell WT, Weiss MH, Law RE, Hinton DR. Paradoxical elevation of Ki-67 labeling with protein kinase inhibition in malignant gliomas. Journal of Neurosurgery. 82: 461-8. PMID 7861225 DOI: 10.3171/Jns.1995.82.3.0461  0.36
1995 Stohlman SA, Bergmann CC, van der Veen RC, Hinton DR. Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system. Journal of Virology. 69: 684-94. PMID 7815531 DOI: 10.1128/Jvi.69.2.684-694.1995  0.68
1995 Sakamoto T, Hinton DR, Sakamoto H, Gopalakrishna R, Ryan SJ, McDonnell PJ. Thrombin induced cytoskeletal change in cultured bovine corneal endothelial cells mediated via protein kinase C pathway. Current Eye Research. 14: 35-45. PMID 7720404 DOI: 10.3109/02713689508999912  0.88
1995 Becker LE, Hinton DR. Pathogenesis of craniosynostosis. Pediatric Neurosurgery. 22: 104-7. PMID 7710971 DOI: 10.1159/000120885  0.88
1995 Cua DJ, Hinton DR, Kirkman L, Stohlman SA. Macrophages regulate induction of delayed-type hypersensitivity and experimental allergic encephalomyelitis in SJL mice. European Journal of Immunology. 25: 2318-24. PMID 7664794 DOI: 10.1002/Eji.1830250830  0.68
1995 Kimura H, Sakamoto T, Hinton DR, Spee C, Ogura Y, Tabata Y, Ikada Y, Ryan SJ. A new model of subretinal neovascularization in the rabbit. Investigative Ophthalmology & Visual Science. 36: 2110-9. PMID 7657549  0.72
1995 Murphy TL, Sakamoto T, Hinton DR, Spee C, Gundimeda U, Soriano D, Gopalakrishna R, Ryan SJ. Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C. Experimental Eye Research. 60: 683-95. PMID 7641851 DOI: 10.1016/S0014-4835(05)80010-7  0.88
1995 Stohlman SA, Hinton DR, Cua D, Dimacali E, Sensintaffar J, Hofman FM, Tahara SM, Yao Q. Tumor necrosis factor expression during mouse hepatitis virus-induced demyelinating encephalomyelitis. Journal of Virology. 69: 5898-903. PMID 7637037 DOI: 10.1128/Jvi.69.9.5898-5903.1995  0.68
1995 Rabinowicz AL, Hinton DR, Dyck P, Couldwell WT. High-dose tamoxifen in treatment of brain tumors: interaction with antiepileptic drugs. Epilepsia. 36: 513-5. PMID 7614929 DOI: 10.1111/J.1528-1157.1995.Tb00494.X  0.36
1995 Cantin EM, Hinton DR, Chen J, Openshaw H. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. Journal of Virology. 69: 4898-905. PMID 7609058 DOI: 10.1128/Jvi.69.8.4898-4905.1995  0.4
1995 Pegolo G, Buckwalter JG, Weiss MH, Hinton DR. Pituitary adenomas. Correlation of the cytologic appearance with biologic behavior. Acta Cytologica. 39: 887-92. PMID 7571965  0.32
1995 Cua DJ, Hinton DR, Stohlman SA. Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 155: 4052-9. PMID 7561116  0.68
1995 Sippy BD, Hofman FM, He S, Osusky R, Sheu SJ, Walker SM, Ryan SJ, Hinton DR. SV40-immortalized and primary cultured human retinal pigment epithelial cells share similar patterns of cytokine-receptor expression and cytokine responsiveness. Current Eye Research. 14: 495-503. PMID 7545567 DOI: 10.3109/02713689509003761  0.88
1995 Sakamoto T, Ishibashi T, Kimura H, Yoshikawa H, Spee C, Harris MS, Hinton DR, Ryan SJ. Effect of tecogalan sodium on angiogenesis in vitro by choroidal endothelial cells. Investigative Ophthalmology & Visual Science. 36: 1076-83. PMID 7537258  0.88
1995 Sakamoto T, Sakamoto H, Murphy TL, Spee C, Soriano D, Ishibashi T, Hinton DR, Ryan SJ. Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells. Archives of Ophthalmology. 113: 512-20. PMID 7536000 DOI: 10.1001/Archopht.1995.01100040134039  0.72
1995 Rabinowicz AL, Abrey LE, Hinton DR, Couldwell WT. Cerebral neurocytoma: an unusual cause of refractory epilepsy. Case report and review of the literature. Epilepsia. 36: 1237-40. PMID 7489702 DOI: 10.1111/J.1528-1157.1995.Tb01068.X  0.36
1994 Couldwell WT, Hinton DR, He S, Chen TC, Sebat I, Weiss MH, Law RE. Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. Febs Letters. 345: 43-6. PMID 8194597 DOI: 10.1016/0014-5793(94)00415-3  0.88
1994 Robinson DL, Destian S, Hinton DR. Synovial sarcoma of the neck: radiographic findings with a review of the literature. American Journal of Otolaryngology. 15: 46-53. PMID 8135329 DOI: 10.1016/0196-0709(94)90040-X  0.88
1994 Sakamoto T, Sakamoto H, Sheu SJ, Gabrielian K, Ryan SJ, Hinton DR. Intercellular gap formation induced by thrombin in confluent cultured bovine retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 35: 720-9. PMID 8113023  0.72
1994 Litofsky NS, Hinton D, Raffel C. The lack of a role for p53 in astrocytomas in pediatric patients Neurosurgery. 34: 967-973. PMID 8084407 DOI: 10.1227/00006123-199406000-00003  0.88
1994 He S, Wang HM, Ye J, Ogden TE, Ryan SJ, Hinton DR. Dexamethasone induced proliferation of cultured retinal pigment epithelial cells. Current Eye Research. 13: 257-61. PMID 8033587 DOI: 10.3109/02713689408995786  0.88
1994 Gabrielian K, Osusky R, Sippy BD, Ryan SJ, Hinton DR. Effect of TGF-beta on interferon-gamma-induced HLA-DR expression in human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 35: 4253-9. PMID 8002245  0.72
1994 Sakamoto T, Hinton DR, Sakamoto H, Oganesian A, Kohen L, Gopalakrishna R, Ryan SJ. Collagen gel contraction induced by retinal pigment epithelial cells and choroidal fibroblasts involves the protein kinase C pathway. Current Eye Research. 13: 451-9. PMID 7924409 DOI: 10.3109/02713689408999873  0.88
1994 Couldwell WT, Hinton DR, Law RE. Protein kinase C and growth regulation in malignant gliomas. Neurosurgery. 35: 1184-6. PMID 7885569 DOI: 10.1227/00006123-199412000-00029  0.36
1994 Chen TC, Hinton DR, Leichman L, Atkinson RD, Apuzzo ML, Couldwell WT. Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report. Neurosurgery. 35: 1138-42; discussion . PMID 7885561 DOI: 10.1227/00006123-199412000-00019  0.36
1994 Kureshi SA, Hofman FM, Schneider JH, Chin LS, Apuzzo ML, Hinton DR. Cytokine expression in radiation-induced delayed cerebral injury. Neurosurgery. 35: 822-9; discussion 82. PMID 7838329 DOI: 10.1227/00006123-199411000-00004  0.4
1994 Jones KD, Couldwell WT, Hinton DR, Su Y, He S, Anker L, Law RE. Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells. Biochemical and Biophysical Research Communications. 205: 1681-7. PMID 7811252 DOI: 10.1006/Bbrc.1994.2861  0.88
1994 Couldwell WT, Gopalakrishna R, Hinton DR, He S, Weiss MH, Law RE, Apuzzo ML, Law RE. Hypericin: a potential antiglioma therapy. Neurosurgery. 35: 705-9; discussion 70. PMID 7808614 DOI: 10.1227/00006123-199410000-00017  0.88
1994 Ahmadi J, Hinton DR, Segall HD, Couldwell WT. Surgical implications of magnetic resonance-enhanced dura. Neurosurgery. 35: 370-7;discussion 377. PMID 7800128 DOI: 10.1227/00006123-199409000-00003  0.36
1994 Sheu SJ, Sakamoto T, Osusky R, Wang HM, Ogden TE, Ryan SJ, Hinton DR, Gopalakrishna R. Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 232: 695-701. PMID 7531168 DOI: 10.1007/Bf00171387  0.88
1994 Hofman FM, Dohadwala MM, Wright AD, Hinton DR, Walker SM. Exogenous tat protein activates central nervous system-derived endothelial cells. Journal of Neuroimmunology. 54: 19-28. PMID 7523444 DOI: 10.1016/0165-5728(94)90226-7  0.32
1993 Couldwell WT, Weiss MH, DeGiorgio CM, Weiner LP, Hinton DR, Ehresmann GR, Conti PS, Apuzzo ML. Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen. Neurosurgery. 32: 485-9; discussion 48. PMID 8384328 DOI: 10.1227/00006123-199303000-00034  0.36
1993 Ahmadi J, Hinton DR, Segall HD, Couldwell WT, Stanley RB. Dural invasion by craniofacial and calvarial neoplasms: MR imaging and histopathologic evaluation. Radiology. 188: 747-9. PMID 8351343 DOI: 10.1148/Radiology.188.3.8351343  0.36
1993 Chin LS, Rabb CH, Hinton DR, Apuzzo ML. Hemangiopericytoma of the temporal bone presenting as a retroauricular mass. Neurosurgery. 33: 728-31; discussion 7. PMID 8232815 DOI: 10.1227/00006123-199310000-00025  0.4
1993 Fleming JO, Wang FI, Trousdale MD, Hinton DR, Stohlman SA. Interaction of immune and central nervous systems: contribution of anti-viral Thy-1+ cells to demyelination induced by coronavirus JHM. Regional Immunology. 5: 37-43. PMID 8102242  0.68
1993 Chen TC, Hinton DR, Apuzzo ML, Hofman FM. Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas. Neurosurgery. 32: 85-94. PMID 8093640 DOI: 10.1227/00006123-199301000-00013  0.32
1992 Schneider J, Hofman FM, Apuzzo ML, Hinton DR. Cytokines and immunoregulatory molecules in malignant glial neoplasms. Journal of Neurosurgery. 77: 265-73. PMID 1625016 DOI: 10.3171/Jns.1992.77.2.0265  0.32
1992 Hofman FM, Hinton DR. Tumor necrosis factor-alpha in the retina in acquired immune deficiency syndrome. Investigative Ophthalmology & Visual Science. 33: 1829-35. PMID 1582785  0.88
1992 Merrill JE, Kono DH, Clayton J, Ando DG, Hinton DR, Hofman FM. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proceedings of the National Academy of Sciences of the United States of America. 89: 574-8. PMID 1370583 DOI: 10.1073/Pnas.89.2.574  0.88
1992 Levy ML, Tung H, Couldwell WT, Hinton DR, Apuzzo ML. Neurosurgery, molecular medicine, and the Pandora-Panacea continuum: future implications for glioma therapy? Clinical Neurosurgery. 39: 421-62. PMID 1360886  0.36
1992 Soong NW, Hinton DR, Cortopassi G, Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nature Genetics. 2: 318-23. PMID 1303287 DOI: 10.1038/Ng1292-318  0.88
1991 Openshaw H, Hinton DR, Slatkin NE, Bierman PJ, Hoffman FM, Snyder DS. Exacerbation of inflammatory demyelinating polyneuropathy after bone marrow transplantation. Bone Marrow Transplantation. 7: 411-4. PMID 1906357  0.88
1991 Hofman FM, Hinton DR, Baemayr J, Weil M, Merrill JE. Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clinical Immunology and Immunopathology. 58: 331-42. PMID 1900461 DOI: 10.1016/0090-1229(91)90124-S  0.88
1991 Blanks JC, Torigoe Y, Hinton DR, Blanks RH. Retinal degeneration in the macula of patients with Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 44-6. PMID 1776758 DOI: 10.1111/J.1749-6632.1991.Tb00188.X  0.88
1991 Chin LS, Hinton DR. The standardized assessment of argyrophilic nucleolar organizer regions in meningeal tumors. Journal of Neurosurgery. 74: 590-6. PMID 1705973 DOI: 10.3171/Jns.1991.74.4.0590  0.88
1990 Hinton DR, Blanks JC, Fong HK, Casey PJ, Hildebrandt E, Simons MI. Novel localization of a G protein, Gz-alpha, in neurons of brain and retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2763-70. PMID 2117645 DOI: 10.1523/Jneurosci.10-08-02763.1990  0.88
1990 Boelter WD, Burt BA, Spector EB, Hinton DR, Pavlova Z, Fujimoto A. Dystrophin protein and RFLP analysis for fetal diagnosis and carrier confirmation of Duchenne muscular dystrophy. Prenatal Diagnosis. 10: 703-15. PMID 1980950 DOI: 10.1002/Pd.1970101104  0.88
1990 Fleming JO, Wang FI, Trousdale MD, Hinton DR, Stohlman SA. Immunopathogenesis of demyelination induced by MHV-4. Advances in Experimental Medicine and Biology. 276: 565-72. PMID 1966450 DOI: 10.1007/978-1-4684-5823-7_78  0.68
1990 Hofman FM, Hinton DR. Cytokine interactions in the central nervous system. Regional Immunology. 3: 268-78. PMID 1716950  0.88
1989 Blanks JC, Hinton DR, Sadun AA, Miller CA. Retinal ganglion cell degeneration in Alzheimer's disease. Brain Research. 501: 364-72. PMID 2819446 DOI: 10.1016/0006-8993(89)90653-7  0.88
1989 Hofman FM, Hinton DR, Johnson K, Merrill JE. Tumor necrosis factor identified in multiple sclerosis brain. The Journal of Experimental Medicine. 170: 607-12. PMID 2754393 DOI: 10.1084/Jem.170.2.607  0.88
1988 Hinton DR, Henderson VW, Blanks JC, Rudnicka M, Miller CA. Monoclonal antibodies react with neuronal subpopulations in the human nervous system. The Journal of Comparative Neurology. 267: 398-408. PMID 3343408 DOI: 10.1002/Cne.902670309  0.88
1987 Sadun AA, Borchert M, DeVita E, Hinton DR, Bassi CJ. Assessment of visual impairment in patients with Alzheimer's disease. American Journal of Ophthalmology. 104: 113-20. PMID 3618708 DOI: 10.1016/0002-9394(87)90001-8  0.88
1987 Miller CA, Rudnicka M, Hinton DR, Blanks JC, Kozlowski M. Monoclonal antibody identification of subpopulations of cerebral cortical neurons affected in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 84: 8657-61. PMID 3120196 DOI: 10.1073/Pnas.84.23.8657  0.88
1986 Hinton DR, Sadun AA, Blanks JC, Miller CA. Optic-nerve degeneration in Alzheimer's disease. The New England Journal of Medicine. 315: 485-7. PMID 3736630 DOI: 10.1056/Nejm198608213150804  0.88
1984 Hinton DR, Halliday WC. Primary rhabdomyosarcoma of the cerebellum--a light, electron microscopic, and immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 43: 439-49. PMID 6737010 DOI: 10.1097/00005072-198407000-00008  0.88
1984 Perry TL, Kish SJ, Hinton D, Hansen S, Becker LE, Gelfand EW. Neurochemical abnormalities in a patient with ataxia-telangiectasia. Neurology. 34: 187-91. PMID 6320055 DOI: 10.1212/Wnl.34.2.187  0.88
1983 Sima AA, Hinton D. Hirano-bodies in the distal symmetric polyneuropathy of the spontaneously diabetic BB-Wistar rat. Acta Neurologica Scandinavica. 68: 107-12. PMID 6314728 DOI: 10.1111/j.1600-0404.1983.tb04824.x  0.88
1983 Becker LE, Hinton D. Primitive neuroectodermal tumors of the central nervous system Human Pathology. 14: 538-550. PMID 6303940 DOI: 10.1016/S0046-8177(83)80006-9  0.88
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