Year |
Citation |
Score |
2020 |
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, ... ... Huang EJ, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7 |
0.714 |
|
2020 |
Mondo E, Becker SC, Kautzman AG, Schifferer M, Baer CE, Chen J, Huang EJ, Simons M, Schafer DP. A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32661024 DOI: 10.1523/Jneurosci.3006-19.2020 |
0.325 |
|
2020 |
Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant mice, a model of motor neuron degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345721 DOI: 10.1073/Pnas.1913956117 |
0.367 |
|
2020 |
Bayraktar OA, Bartels T, Holmqvist S, Kleshchevnikov V, Martirosyan A, Polioudakis D, Ben Haim L, Young AMH, Batiuk MY, Prakash K, Brown A, Roberts K, Paredes MF, Kawaguchi R, Stockley JH, ... ... Huang E, et al. Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map. Nature Neuroscience. PMID 32203496 DOI: 10.1038/S41593-020-0602-1 |
0.327 |
|
2020 |
Kuang L, Hashimoto K, Huang EJ, Gentry MS, Zhu H. Frontotemporal dementia nonsense mutation of progranulin rescued by aminoglycosides. Human Molecular Genetics. PMID 31913476 DOI: 10.1093/Hmg/Ddz280 |
0.333 |
|
2019 |
Zhang J, Shang Y, Kamiya S, Kotowski SJ, Nakamura K, Huang EJ. Loss of HIPK2 protects neurons from mitochondrial toxins by regulating Parkin protein turnover. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31776210 DOI: 10.1523/Jneurosci.2017-19.2019 |
0.34 |
|
2019 |
Nolan A, De Paula Franca Resende E, Petersen C, Neylan K, Spina S, Huang E, Seeley W, Miller Z, Grinberg LT. Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations. Journal of Neuropathology and Experimental Neurology. PMID 31626288 DOI: 10.1093/Jnen/Nlz094 |
0.312 |
|
2019 |
Sorrells SF, Paredes MF, Velmeshev D, Herranz-Pérez V, Sandoval K, Mayer S, Chang EF, Insausti R, Kriegstein AR, Rubenstein JL, Manuel Garcia-Verdugo J, Huang EJ, Alvarez-Buylla A. Immature excitatory neurons develop during adolescence in the human amygdala. Nature Communications. 10: 2748. PMID 31227709 DOI: 10.1038/S41467-019-10765-1 |
0.363 |
|
2019 |
Arnold TD, Lizama CO, Cautivo KM, Santander N, Lin L, Qiu H, Huang EJ, Liu C, Mukouyama YS, Reichardt LF, Zovein AC, Sheppard D. Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction. The Journal of Experimental Medicine. PMID 30846482 DOI: 10.1084/Jem.20181290 |
0.345 |
|
2018 |
Nana AL, Sidhu M, Gaus SE, Hwang JL, Li L, Park Y, Kim EJ, Pasquini L, Allen IE, Rankin KP, Toller G, Kramer JH, Geschwind DH, Coppola G, Huang EJ, et al. Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology. Acta Neuropathologica. PMID 30511086 DOI: 10.1007/S00401-018-1942-8 |
0.404 |
|
2018 |
Hofmann JW, Seeley WW, Huang EJ. RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration. Annual Review of Pathology. PMID 30355151 DOI: 10.1146/Annurev-Pathmechdis-012418-012955 |
0.342 |
|
2018 |
Shang Y, Zhang J, Huang EJ. HIPK2-mediated transcriptional control of NMDA receptor subunit expression regulates neuronal survival and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29581378 DOI: 10.1523/Jneurosci.3577-17.2018 |
0.319 |
|
2018 |
Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, ... Huang EJ, et al. Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature. PMID 29513649 DOI: 10.1038/Nature25975 |
0.327 |
|
2018 |
Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511098 DOI: 10.1073/Pnas.1722344115 |
0.328 |
|
2017 |
Petersen MA, Ryu JK, Chang KJ, Etxeberria A, Bardehle S, Mendiola AS, Kamau-Devers W, Fancy SPJ, Thor A, Bushong EA, Baeza-Raja B, Syme CA, Wu MD, Rios Coronado PE, Meyer-Franke A, ... ... Huang EJ, et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage. Neuron. PMID 29103804 DOI: 10.1016/J.Neuron.2017.10.008 |
0.313 |
|
2017 |
Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, ... ... Huang EJ, et al. Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain : a Journal of Neurology. PMID 29053860 DOI: 10.1093/Brain/Awx254 |
0.336 |
|
2017 |
Lombardi LM, Zaghlula M, Sztainberg Y, Baker SA, Klisch TJ, Tang AA, Huang EJ, Zoghbi HY. An RNA interference screen identifies druggable regulators of MeCP2 stability. Science Translational Medicine. 9. PMID 28835516 DOI: 10.1126/Scitranslmed.Aaf7588 |
0.32 |
|
2017 |
Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, ... ... Huang EJ, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Science Translational Medicine. 9. PMID 28814543 DOI: 10.1126/Scitranslmed.Aag0394 |
0.394 |
|
2017 |
Kao AW, McKay A, Singh PP, Brunet A, Huang EJ. Progranulin, lysosomal regulation and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 28435163 DOI: 10.1038/Nrn.2017.36 |
0.315 |
|
2017 |
Orr AL, Rutaganira FU, de Roulet D, Huang EJ, Hertz NT, Shokat KM, Nakamura K. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochemistry International. PMID 28434973 DOI: 10.1016/J.Neuint.2017.04.006 |
0.304 |
|
2017 |
Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, ... ... Huang EJ, et al. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Science Translational Medicine. 9. PMID 28404863 DOI: 10.1126/Scitranslmed.Aah5642 |
0.345 |
|
2017 |
Cahill MK, Huang EJ. Testing the Amyloid Hypothesis with a Humanized AD Mouse Model. Neuron. 93: 987-989. PMID 28279360 DOI: 10.1016/J.Neuron.2017.02.044 |
0.316 |
|
2017 |
Celona B, von Dollen J, Vatsavayai SC, Kashima R, Johnson JR, Tang AA, Hata A, Miller BL, Huang EJ, Krogan NJ, Seeley WW, Black BL. Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 6. PMID 28072389 DOI: 10.7554/Elife.19032 |
0.344 |
|
2016 |
Luo SX, Timbang L, Kim JI, Shang Y, Sandoval K, Tang AA, Whistler JL, Ding JB, Huang EJ. TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. Cell Reports. 17: 3233-3245. PMID 28009292 DOI: 10.1016/J.Celrep.2016.11.068 |
0.325 |
|
2016 |
Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH, Xu D, McQuillen PS, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A. Extensive migration of young neurons into the infant human frontal lobe. Science (New York, N.Y.). 354. PMID 27846470 DOI: 10.1126/Science.Aaf7073 |
0.336 |
|
2016 |
Lee S, Shang Y, Redmond SA, Urisman A, Tang AA, Li KH, Burlingame AL, Pak RA, Jovičić A, Gitler AD, Wang J, Gray NS, Seeley WW, Siddique T, Bigio EH, ... ... Huang EJ, et al. Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. Neuron. PMID 27321923 DOI: 10.1016/J.Neuron.2016.05.021 |
0.331 |
|
2016 |
Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, ... ... Huang EJ, et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell. PMID 27114033 DOI: 10.1016/J.Cell.2016.04.001 |
0.309 |
|
2016 |
Shang Y, Huang EJ. Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis. Brain Research. PMID 27033831 DOI: 10.1016/J.Brainres.2016.03.036 |
0.348 |
|
2015 |
Luo SX, Huang EJ. Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly. The American Journal of Pathology. PMID 26724386 DOI: 10.1016/J.Ajpath.2015.09.023 |
0.371 |
|
2015 |
Huang EJ. Ventral Midbrain Dopaminergic Neurons: From Neurogenesis to Neurodegeneration. Febs Letters. PMID 26581860 DOI: 10.1016/J.Febslet.2015.11.008 |
0.343 |
|
2015 |
Lee S, Huang EJ. Modeling ALS and FTD with iPSC-derived neurons. Brain Research. PMID 26462653 DOI: 10.1016/J.Brainres.2015.10.003 |
0.36 |
|
2015 |
Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EM, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-6. PMID 26056265 DOI: 10.1073/Pnas.1509744112 |
0.382 |
|
2015 |
Nobuta H, Cilio MR, Danhaive O, Tsai HH, Tupal S, Chang SM, Murnen A, Kreitzer F, Bravo V, Czeisler C, Gokozan HN, Gygli P, Bush S, Weese-Mayer DE, Conklin B, ... ... Huang EJ, et al. Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome. Acta Neuropathologica. 130: 171-83. PMID 25975378 DOI: 10.1007/S00401-015-1441-0 |
0.364 |
|
2015 |
Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nature Communications. 6: 6171. PMID 25625564 DOI: 10.1038/Ncomms7171 |
0.332 |
|
2014 |
Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14304-17. PMID 25339743 DOI: 10.1523/Jneurosci.0930-14.2014 |
0.32 |
|
2014 |
Sephton CF, Tang AA, Kulkarni A, West J, Brooks M, Stubblefield JJ, Liu Y, Zhang MQ, Green CB, Huber KM, Huang EJ, Herz J, Yu G. Activity-dependent FUS dysregulation disrupts synaptic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: E4769-78. PMID 25324524 DOI: 10.1073/Pnas.1406162111 |
0.348 |
|
2014 |
Hsieh CL, Niemi EC, Wang SH, Lee CC, Bingham D, Zhang J, Cozen ML, Charo I, Huang EJ, Liu J, Nakamura MC. CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury. Journal of Neurotrauma. 31: 1677-88. PMID 24806994 DOI: 10.1089/Neu.2013.3252 |
0.304 |
|
2014 |
Fancy SP, Harrington EP, Baranzini SE, Silbereis JC, Shiow LR, Yuen TJ, Huang EJ, Lomvardas S, Rowitch DH. Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nature Neuroscience. 17: 506-12. PMID 24609463 DOI: 10.1038/Nn.3676 |
0.3 |
|
2014 |
Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, ... ... Huang EJ, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 124: 981-99. PMID 24509083 DOI: 10.1172/Jci72723 |
0.376 |
|
2013 |
Stephan AH, Madison DV, Mateos JM, Fraser DA, Lovelett EA, Coutellier L, Kim L, Tsai HH, Huang EJ, Rowitch DH, Berns DS, Tenner AJ, Shamloo M, Barres BA. A dramatic increase of C1q protein in the CNS during normal aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13460-74. PMID 23946404 DOI: 10.1523/Jneurosci.1333-13.2013 |
0.316 |
|
2013 |
Heng MY, Lin ST, Verret L, Huang Y, Kamiya S, Padiath QS, Tong Y, Palop JJ, Huang EJ, PtáÄek LJ, Fu YH. Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. The Journal of Clinical Investigation. 123: 2719-29. PMID 23676464 DOI: 10.1172/Jci66737 |
0.316 |
|
2013 |
Tang M, Luo SX, Tang V, Huang EJ. Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development. Neural Development. 8: 8. PMID 23618354 DOI: 10.1186/1749-8104-8-8 |
0.346 |
|
2013 |
Shang Y, Doan CN, Arnold TD, Lee S, Tang AA, Reichardt LF, Huang EJ. Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism. Plos Biology. 11: e1001527. PMID 23565059 DOI: 10.1371/Journal.Pbio.1001527 |
0.301 |
|
2013 |
Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5352-61. PMID 23516300 DOI: 10.1523/Jneurosci.6103-11.2013 |
0.36 |
|
2013 |
Vossel KA, Bien-Ly N, Bernardo A, Rascovsky K, Karydas A, Rabinovici GD, Sidhu M, Huang EJ, Miller BL, Huang Y, Seeley WW. ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease. Neurocase. 19: 295-301. PMID 22512241 DOI: 10.1080/13554794.2012.667124 |
0.356 |
|
2012 |
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113 |
0.382 |
|
2012 |
Nobuta H, Ghiani CA, Paez PM, Spreuer V, Dong H, Korsak RA, Manukyan A, Li J, Vinters HV, Huang EJ, Rowitch DH, Sofroniew MV, Campagnoni AT, de Vellis J, Waschek JA. STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Annals of Neurology. 72: 750-65. PMID 22941903 DOI: 10.1002/Ana.23670 |
0.316 |
|
2012 |
Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, Rašin MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, et al. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell. 149: 899-911. PMID 22579290 DOI: 10.1016/J.Cell.2012.02.060 |
0.384 |
|
2012 |
Revet I, Feeney L, Tang AA, Huang EJ, Cleaver JE. Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome. Proceedings of the National Academy of Sciences of the United States of America. 109: 4627-32. PMID 22393014 DOI: 10.1073/Pnas.1202621109 |
0.305 |
|
2012 |
Kim EJ, Sidhu M, Gaus SE, Huang EJ, Hof PR, Miller BL, DeArmond SJ, Seeley WW. Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia. Cerebral Cortex (New York, N.Y. : 1991). 22: 251-9. PMID 21653702 DOI: 10.1093/Cercor/Bhr004 |
0.38 |
|
2012 |
Filiano A, Martens LH, Young A, Warmus B, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang E, Gao F, Farese R, Roberson E. O1-05-03: Neuronal effects of progranulin deficiency contribute to frontotemporal dementia independent of neuroinflammation Alzheimer's & Dementia. 8: P93-P93. DOI: 10.1016/J.Jalz.2012.05.228 |
0.325 |
|
2011 |
Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, Rowitch DH, Alvarez-Buylla A. Corridors of migrating neurons in the human brain and their decline during infancy. Nature. 478: 382-6. PMID 21964341 DOI: 10.1038/Nature10487 |
0.346 |
|
2011 |
Chalazonitis A, Tang AA, Shang Y, Pham TD, Hsieh I, Setlik W, Gershon MD, Huang EJ. Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13746-57. PMID 21957238 DOI: 10.1523/Jneurosci.1078-11.2011 |
0.4 |
|
2011 |
Lee CS, Lee C, Hu T, Nguyen JM, Zhang J, Martin MV, Vawter MP, Huang EJ, Chan JY. Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 108: 8408-13. PMID 21536885 DOI: 10.1073/Pnas.1019209108 |
0.339 |
|
2010 |
Reyes NA, Fisher JK, Austgen K, VandenBerg S, Huang EJ, Oakes SA. Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis. The Journal of Clinical Investigation. 120: 3673-9. PMID 20890041 DOI: 10.1172/Jci42986 |
0.363 |
|
2010 |
Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, Taketo MM, Arenas E, Huang EJ. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9280-91. PMID 20610763 DOI: 10.1523/Jneurosci.0860-10.2010 |
0.32 |
|
2010 |
Huang EJ, Zhang J, Geser F, Trojanowski JQ, Strober JB, Dickson DW, Brown RH, Shapiro BE, Lomen-Hoerth C. Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions. Brain Pathology (Zurich, Switzerland). 20: 1069-76. PMID 20579074 DOI: 10.1111/J.1750-3639.2010.00413.X |
0.365 |
|
2009 |
Tang M, Miyamoto Y, Huang EJ. Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. Development (Cambridge, England). 136: 2027-38. PMID 19439492 DOI: 10.1242/Dev.034330 |
0.34 |
|
2008 |
Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proceedings of the National Academy of Sciences of the United States of America. 105: 10595-600. PMID 18647832 DOI: 10.1073/Pnas.0803671105 |
0.314 |
|
2008 |
Tang A, Chalazonitis A, Pham T, Hsieh I, Gershon M, Huang E. Essential role of TGFβ-HIPK2 signaling pathway in survival and synapse formation in enteric neurons International Journal of Developmental Neuroscience. 26: 862. DOI: 10.1016/J.Ijdevneu.2008.09.112 |
0.327 |
|
2007 |
Laposa RR, Huang EJ, Cleaver JE. Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1389-94. PMID 17229834 DOI: 10.1073/Pnas.0610619104 |
0.318 |
|
2007 |
Zhang J, Pho V, Bonasera SJ, Holtzman J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott LH, Huang EJ. Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nature Neuroscience. 10: 77-86. PMID 17159989 DOI: 10.1038/Nn1816 |
0.374 |
|
2006 |
Kauppinen TM, Chan WY, Suh SW, Wiggins AK, Huang EJ, Swanson RA. Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. Proceedings of the National Academy of Sciences of the United States of America. 103: 7136-41. PMID 16627622 DOI: 10.1073/Pnas.0508606103 |
0.338 |
|
2005 |
Lynn S, Huang EJ, Elchuri S, Naeemuddin M, Nishinaka Y, Yodoi J, Ferriero DM, Epstein CJ, Huang TT. Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. Free Radical Biology & Medicine. 38: 817-28. PMID 15721992 DOI: 10.1016/J.Freeradbiomed.2004.12.020 |
0.342 |
|
2005 |
Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ. Notch-1 activation and dendritic atrophy in prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 886-91. PMID 15640354 DOI: 10.1073/Pnas.0408612101 |
0.357 |
|
2004 |
Wiggins AK, Wei G, Doxakis E, Wong C, Tang AA, Zang K, Luo EJ, Neve RL, Reichardt LF, Huang EJ. Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. The Journal of Cell Biology. 167: 257-67. PMID 15492043 DOI: 10.1083/Jcb.200406131 |
0.368 |
|
2004 |
Doxakis E, Huang EJ, Davies AM. Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons. Current Biology : Cb. 14: 1761-5. PMID 15458648 DOI: 10.1016/J.Cub.2004.09.050 |
0.353 |
|
2001 |
Huang EJ, Reichardt LF. Neurotrophins: roles in neuronal development and function. Annual Review of Neuroscience. 24: 677-736. PMID 11520916 DOI: 10.1146/Annurev.Neuro.24.1.677 |
0.334 |
|
2001 |
Fariñas I, Jones KR, Tessarollo L, Vigers AJ, Huang E, Kirstein M, de Caprona DC, Coppola V, Backus C, Reichardt LF, Fritzsch B. Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6170-80. PMID 11487640 DOI: 10.1523/Jneurosci.21-16-06170.2001 |
0.355 |
|
2000 |
Fan G, Copray S, Huang EJ, Jones K, Yan Q, Walro J, Jaenisch R, Kucera J. Formation of a full complement of cranial proprioceptors requires multiple neurotrophins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 359-70. PMID 10842362 DOI: 10.1002/(Sici)1097-0177(200006)218:2<359::Aid-Dvdy9>3.0.Co;2-L |
0.354 |
|
1998 |
Tajima Y, Huang EJ, Vosseller K, Ono M, Moore MA, Besmer P. Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: the Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis. The Journal of Experimental Medicine. 187: 1451-61. PMID 9565637 DOI: 10.1084/Jem.187.9.1451 |
0.307 |
|
1993 |
Huang EJ, Manova K, Packer AI, Sanchez S, Bachvarova RF, Besmer P. The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles. Developmental Biology. 157: 100-9. PMID 7683280 DOI: 10.1006/Dbio.1993.1115 |
0.32 |
|
1992 |
Huang EJ, Nocka KH, Buck J, Besmer P. Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2. Molecular Biology of the Cell. 3: 349-62. PMID 1378327 DOI: 10.1091/Mbc.3.3.349 |
0.317 |
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1992 |
Manova K, Bachvarova RF, Huang EJ, Sanchez S, Pronovost SM, Velazquez E, McGuire B, Besmer P. c-kit receptor and ligand expression in postnatal development of the mouse cerebellum suggests a function for c-kit in inhibitory interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4663-76. PMID 1281492 DOI: 10.1523/Jneurosci.12-12-04663.1992 |
0.334 |
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