Marjorie B. Lees - Publications

Affiliations: 
Neurobiology University of Massachusetts, Amherst, MA, United States 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Greenfield EA, Reddy J, Lees A, Dyer CA, Koul O, Nguyen K, Bell S, Kassam N, Hinojoza J, Eaton MJ, Lees MB, Kuchroo VK, Sobel RA. Monoclonal antibodies to distinct regions of human myelin proteolipid protein simultaneously recognize central nervous system myelin and neurons of many vertebrate species. Journal of Neuroscience Research. 83: 415-31. PMID 16416423 DOI: 10.1002/Jnr.20748  0.7
2002 Greer JM, Lees MB. Myelin proteolipid protein--the first 50 years. The International Journal of Biochemistry & Cell Biology. 34: 211-5. PMID 11849988 DOI: 10.1016/S1357-2725(01)00136-4  0.479
1999 Santambrogio L, Pakaski M, Wong ML, Cipriani B, Brosnan CF, Lees MB, Dorf ME. Antigen presenting capacity of brain microvasculature in altered peptide ligand modulation of experimental allergic encephalomyelitis. Journal of Neuroimmunology. 93: 81-91. PMID 10378871 DOI: 10.1016/S0165-5728(98)00203-3  0.323
1999 Yamada M, Ivanova A, Yamaguchi Y, Lees MB, Ikenaka K. Proteolipid protein gene product can be secreted and exhibit biological activity during early development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2143-51. PMID 10066267 DOI: 10.1523/Jneurosci.19-06-02143.1999  0.363
1999 Bizzozero OA, Lees MB. Fatty acid composition of myelin proteolipid protein during vertebrate evolution. Neurochemical Research. 24: 269-74. PMID 9972874 DOI: 10.1023/A:1022518206037  0.711
1998 Lees MB. A history of proteolipids: a personal memoir. Neurochemical Research. 23: 261-71. PMID 9482238 DOI: 10.1023/A:1022488912996  0.395
1996 Stephens TS, Pakaski M, Lees MB, Potter NT. Identification and characterization of a B-cell determinant within the amphipathic domain (residues 178-238) of the myelin proteolipid protein. Journal of Neuroscience Research. 43: 545-53. PMID 8833089 DOI: 10.1002/(Sici)1097-4547(19960301)43:5<545::Aid-Jnr4>3.0.Co;2-I  0.49
1996 Greer JM, Dyer CA, Pakaski M, Symonowicz C, Lees MB. Orientation of myelin proteolipid protein in the oligodendrocyte cell membrane. Neurochemical Research. 21: 431-40. PMID 8734436 DOI: 10.1007/Bf02527707  0.46
1995 Genain CP, Nguyen MH, Letvin NL, Pearl R, Davis RL, Adelman M, Lees MB, Linington C, Hauser SL. Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate. The Journal of Clinical Investigation. 96: 2966-74. PMID 8675668 DOI: 10.1172/Jci118368  0.35
1995 Nicholson LB, Greer JM, Sobel RA, Lees MB, Kuchroo VK. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity. 3: 397-405. PMID 7584131 DOI: 10.1016/1074-7613(95)90169-8  0.323
1995 Lees MB, Smith FI, Dyer CA, Greer JM, Pakaski M. Expression of myelin proteolipid protein in oligodendrocytes and transfected cells. Progress in Brain Research. 105: 295-303. PMID 7568890 DOI: 10.1016/S0079-6123(08)63307-5  0.389
1994 Sobel RA, Greer JM, Isaac J, Fondren G, Lees MB. Immunolocalization of proteolipid protein peptide 103-116 in myelin. Journal of Neuroscience Research. 37: 36-43. PMID 7511704 DOI: 10.1002/Jnr.490370106  0.466
1993 Kerlero de Rosbo N, Milo R, Lees MB, Burger D, Bernard CC, Ben-Nun A. Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein. The Journal of Clinical Investigation. 92: 2602-8. PMID 7504688 DOI: 10.1172/Jci116875  0.33
1993 Sobel RA, Greer JM, Isaac J, Fondren G, Lees MB. IMMUNOLOCALIZATION OF PROTEOLIPED PROTEIN (PLP) PEPTIDE 103–116 IN OLIGODENDROCYTES AND MYELIN Journal of Neuropathology and Experimental Neurology. 52: 287. DOI: 10.1097/00005072-199305000-00109  0.456
1992 Tuohy VK, Sobel RA, Lu Z, Laursen RA, Lees MB. Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice. Journal of Neuroimmunology. 39: 67-74. PMID 1377711 DOI: 10.1016/0165-5728(92)90175-K  0.374
1992 Konola JT, Yamamura T, Tyler B, Lees MB. Orientation of the myelin proteolipid protein C-terminus in oligodendroglial membranes. Glia. 5: 112-21. PMID 1374364 DOI: 10.1002/Glia.440050205  0.496
1991 Yamamura T, Konola JT, Wekerle H, Lees MB. Monoclonal antibodies against myelin proteolipid protein: identification and characterization of two major determinants. Journal of Neurochemistry. 57: 1671-80. PMID 1717653 DOI: 10.1111/J.1471-4159.1991.Tb06367.X  0.426
1991 Kuchroo VK, Sobel RA, Yamamura T, Greenfield E, Dorf ME, Lees MB. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 59: 305-12. PMID 1716908 DOI: 10.1159/000163668  0.464
1991 Konola LT, Tyler BM, Yamamura T, Lees MB. Distribution of proteolipid protein and myelin basic protein in cultured mouse oligodendrocytes: primary vs. secondary cultures. Journal of Neuroscience Research. 28: 49-64. PMID 1710282 DOI: 10.1002/Jnr.490280106  0.392
1991 Bizzozero OA, Zuñiga G, Lees MB. Fatty acid composition of human myelin proteolipid protein in peroxisomal disorders. Journal of Neurochemistry. 56: 872-8. PMID 1704424 DOI: 10.1111/J.1471-4159.1991.Tb02003.X  0.673
1991 Kuchroo VK, Sobel RA, Laning JC, Greenfield E, Ju S, Dorf ME, Lees MB. Heterogeneity of T cell clones specific for an encephalitogenic determinant of myelin proteolipid protein (PLP) Journal of Neuroimmunology. 35: 44. DOI: 10.1016/0165-5728(91)90913-R  0.433
1991 Sobel RA, Kuchroo VK, Wang Y, Dorf ME, Lees MB. Heterogeneous T cell receptor (TcR) Vβs of acute experimental allergic encephalomyelitis (EAE) induced with a myelin proteolipid protein (PLP) peptide and peptide-specific T cell clones Journal of Neuroimmunology. 35: 43. DOI: 10.1016/0165-5728(91)90912-Q  0.342
1991 Lees MB, Kuchroo VK, Sobel RA. Myelin proteolipid protein: Its role in experimental allergic encephalomyelitis International Pediatrics. 6: 84-90.  0.372
1990 Sobel RA, Tuohy VK, Lu ZJ, Laursen RA, Lees MB. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. Journal of Neuropathology and Experimental Neurology. 49: 468-79. PMID 2273404 DOI: 10.1097/00005072-199009000-00002  0.374
1990 Konola JT, Tyler BM, Lees MB. Proteolipid protein and myelin basic protein in secondary mouse oligodendrocyte cultures Annals of the New York Academy of Sciences. 605: 366-368. DOI: 10.1111/J.1749-6632.1990.Tb42414.X  0.475
1989 Bizzozero OA, Odykirk TS, McGarry JF, Lees MB. Separation of the major proteins of central and peripheral nervous system myelin using reversed-phase high-performance liquid chromatography. Analytical Biochemistry. 180: 59-65. PMID 2817345 DOI: 10.1016/0003-2697(89)90087-0  0.713
1989 Shaw SY, Laursen RA, Lees MB. Identification of thiol groups and a disulfide crosslink site in bovine myelin proteolipid protein. Febs Letters. 250: 306-10. PMID 2473918 DOI: 10.1016/0014-5793(89)80744-6  0.447
1988 Potter NT, Lees MB. Immunochemical characterization of antibodies to the myelin proteolipid protein (PLP). Journal of Neuroimmunology. 18: 49-60. PMID 2450106 DOI: 10.1016/0165-5728(88)90134-8  0.436
1987 Bizzozero OA, McGarry JF, Lees MB. Acylation of endogenous myelin proteolipid protein with different acyl-CoAs. The Journal of Biological Chemistry. 262: 2138-45. PMID 3818589  0.418
1987 Bizzozero OA, McGarry JF, Lees MB. Autoacylation of myelin proteolipid protein with acyl coenzyme A. The Journal of Biological Chemistry. 262: 13550-7. PMID 2443494  0.412
1987 Tuohy V, Sobel R, Lees M. EAE induced by myelin proteolipid apoprotein (PLP) in various strains of mice Journal of Neuroimmunology. 16: 174. DOI: 10.1016/0165-5728(87)90400-0  0.335
1987 Potter NT, Lees MB. Immunochemistry of the myelin proteolipid protein Journal of Neuroimmunology. 16: 141. DOI: 10.1016/0165-5728(87)90348-1  0.498
1986 Bizzozero OA, Lees MB. Spectroscopic analysis of acylated and deacylated myelin proteolipid protein. Biochemistry. 25: 6762-8. PMID 2432924 DOI: 10.1021/Bi00370A006  0.678
1986 Lin LF, Bartlett C, Lees MB. Preparation and characterization of unilamellar myelin vesicles. The Journal of Biological Chemistry. 261: 16241-6. PMID 2430966  0.319
1986 Shaw SY, Laursen RA, Lees MB. Analogous amino acid sequences in myelin proteolipid and viral proteins. Febs Letters. 207: 266-70. PMID 2429866 DOI: 10.1016/0014-5793(86)81502-2  0.499
1986 Johnson D, Hafler DA, Fallis RJ, Lees MB, Brady RO, Quarles RH, Weiner HL. Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosis. Journal of Neuroimmunology. 13: 99-108. PMID 2428837 DOI: 10.1016/0165-5728(86)90053-6  0.38
1986 Bizzozero OA, McGarry JF, Lees MB. Acylation of rat brain myelin proteolipid protein with different fatty acids. Journal of Neurochemistry. 47: 772-8. PMID 2426408 DOI: 10.1111/J.1471-4159.1986.Tb00678.X  0.681
1986 van der Veen RC, Sobel RA, Lees MB. Chronic experimental allergic encephalomyelitis and antibody responses in rabbits immunized with bovine proteolipid apoprotein. Journal of Neuroimmunology. 11: 321-33. PMID 2423554 DOI: 10.1016/0165-5728(86)90085-8  0.339
1986 Bizzozero OA, Lees MB. Fatty acid acylation of rat brain myelin proteolipid protein in vitro: identification of the lipid donor. Journal of Neurochemistry. 46: 630-6. PMID 2416880 DOI: 10.1111/J.1471-4159.1986.Tb13013.X  0.698
1985 Lebar R, Lees MB. Dot immunobinding as a tool for the study of the CNS myelin antigen, M2. Journal of Neuroimmunology. 8: 43-55. PMID 2579096 DOI: 10.1016/S0165-5728(85)80046-1  0.478
1985 Lees MB, Cambi F. Noncontamination of proteolipid protein preparations by MBP. Annals of Neurology. 18: 268. PMID 2412487 DOI: 10.1002/Ana.410180218  0.401
1985 Sohel RA, van der Veen RC, Lees MB. CHRONIC EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (cEAE) INDUCED IN RABBITS BY PRO- TEOLI.PID PROTEIN Journal of Neuropathology and Experimental Neurology. 44: 320. DOI: 10.1097/00005072-198505000-00050  0.341
1984 Lin LF, Lees MB. Dicyclohexylcarbodiimide-binding sites in the myelin proteolipid. Neurochemical Research. 9: 1515-22. PMID 6514113 DOI: 10.1007/Bf00964677  0.312
1984 Cambi F, Lees MB. Chronic experimental allergic encephalomyelitis in guinea pigs: immunologic studies on the two major myelin proteins. Cellular Immunology. 86: 567-74. PMID 6203654 DOI: 10.1016/0008-8749(84)90415-5  0.41
1984 Lees MB, Samiullah M, Laursen RA. Structural analogies between myelin basic protein and proteolipid. Progress in Clinical and Biological Research. 146: 257-64. PMID 6201897  0.363
1984 Laursen RA, Samiullah M, Lees MB. The structure of bovine brain myelin proteolipid and its organization in myelin. Proceedings of the National Academy of Sciences of the United States of America. 81: 2912-6. PMID 6201866 DOI: 10.1073/Pnas.81.9.2912  0.405
1983 Laursen RA, Samiullah M, Lees MB. Gene duplication in bovine brain myelin proteolipid and homology with related proteins. Febs Letters. 161: 71-4. PMID 6884530 DOI: 10.1016/0014-5793(83)80732-7  0.484
1983 Macklin WB, Oberfield E, Lees MB. Electroblot analysis of rat myelin proteolipid protein and basic protein during development. Developmental Neuroscience. 6: 161-8. PMID 6680099 DOI: 10.1159/000112343  0.596
1983 Lees MB, Chao BH, Lin LF, Samiullah M, Laursen RA. Amino acid sequence of bovine white matter proteolipid. Archives of Biochemistry and Biophysics. 226: 643-56. PMID 6195969 DOI: 10.1016/0003-9861(83)90334-X  0.366
1983 Cambi F, Lees MB, Williams RM, Macklin WB. Chronic experimental allergic encephalomyelitis produced by bovine proteolipid apoprotein: immunological studies in rabbits. Annals of Neurology. 13: 303-8. PMID 6189448 DOI: 10.1002/Ana.410130313  0.571
1982 Williams RM, Lees MB, Cambi F, Macklin WB. Chronic experimental allergic encephalomyelitis induced in rabbits with bovine white matter proteolipid apoprotein. Journal of Neuropathology and Experimental Neurology. 41: 508-21. PMID 7108565 DOI: 10.1097/00005072-198209000-00004  0.603
1982 Macklin WB, Lees MB. Solid-phase immunoassays for quantitation of antibody to bovine white matter proteolipid apoprotein. Journal of Neurochemistry. 38: 348-55. PMID 7108542 DOI: 10.1111/J.1471-4159.1982.Tb08635.X  0.593
1982 Lees MB, Chao BH, Laursen RA, L'Italien JJ. A hydrophobic tryptic peptide from bovine white matter proteolipid. Biochimica Et Biophysica Acta. 702: 117-24. PMID 7066340 DOI: 10.1016/0167-4838(82)90034-6  0.309
1982 Lees MB. Proteolipids. Scandinavian Journal of Immunology. Supplement. 9: 147-66. PMID 6763766  0.335
1982 Lin LF, Lees MB. Interactions of dicyclohexylcarbodiimide with myelin proteolipid. Proceedings of the National Academy of Sciences of the United States of America. 79: 941-5. PMID 6278503 DOI: 10.1073/Pnas.79.3.941  0.443
1982 Macklin WB, Braun PE, Lees MB. Electroblot analysis of the myelin proteolipid protein. Journal of Neuroscience Research. 7: 1-10. PMID 6175769 DOI: 10.1002/Jnr.490070102  0.673
1981 Macklin WB, Schwarting GA, Lees MB, Cohen SR. Production and purification of antibody to bovine white matter proteolipid apoprotein. Journal of Neurochemistry. 36: 101-6. PMID 7463040 DOI: 10.1111/J.1471-4159.1981.Tb02383.X  0.629
1981 Lees MB, Macklin WB, Chao BH. A study of elastase peptides from bovine white matter proteolipid. Neurochemical Research. 6: 1091-104. PMID 6917041 DOI: 10.1007/Bf00964415  0.579
1981 Reiss DS, Lees MB, Sapirstein VS. Is Na + ATPase a myelin-associated enzyme? Journal of Neurochemistry. 36: 1418-26. PMID 6267194 DOI: 10.1111/J.1471-4159.1981.Tb00581.X  0.362
1981 Macklin WB, Lees MB, Cohen SR, Ayella SB. Hydrophobic compounds interfere in radioimmunoassay for basic protein in myelin. Clinical Chemistry. 27: 742-4. PMID 6164508 DOI: 10.1093/Clinchem/27.5.742  0.64
1980 Lees MB, Sapirstein VS, Reiss DS, Kolodny EH. Carbonic anhydrase and 2',3' cyclic nucleotide 3'-phosphohydrolase activity in normal human brain and in demyelinating diseases. Neurology. 30: 719-25. PMID 6248817 DOI: 10.1212/Wnl.30.7.719  0.393
1979 Ting-Beall HP, Lees MB, Robertson JD. Interactions of Folch-Lees proteolipid apoprotein with planar lipid bilayers. The Journal of Membrane Biology. 51: 33-46. PMID 522128 DOI: 10.1007/Bf01869342  0.328
1979 Lees MB, Sakura JD, Sapirstein VS, Curatolo W. Structure and function of proteolipids in myelin and non-myelin membranes. Biochimica Et Biophysica Acta. 559: 209-30. PMID 157777 DOI: 10.1016/0304-4157(79)90002-9  0.411
1978 Chan DS, Lees MB. Tryptic peptides from bovine white matter proteolipids. Journal of Neurochemistry. 30: 983-90. PMID 660200 DOI: 10.1111/J.1471-4159.1978.Tb12390.X  0.362
1978 Hess HH, Lees MB, Derr JE. A linear Lowry--Folin assay for both water-soluble and sodium dodecyl sulfate-solubilized proteins. Analytical Biochemistry. 85: 295-300. PMID 629390 DOI: 10.1016/0003-2697(78)90304-4  0.383
1978 Sapirstein V, Trachtenberg M, Lees MB, Koul O. Regional developmental and fractional studies on myelin and other carbonic anhydrases in rat CNS. Advances in Experimental Medicine and Biology. 100: 55-69. PMID 99992 DOI: 10.1007/978-1-4684-2514-7_5  0.405
1978 Sapirstein VS, Lees MB. Purification of myelin carbonic anhydrase. Journal of Neurochemistry. 31: 505-11. PMID 97371 DOI: 10.1111/J.1471-4159.1978.Tb02665.X  0.409
1978 Sapirstein VS, Lees MB, Trachtenberg MC. Soluble and membrane bound carbonic anhydrases from rat CNS: regional development. Journal of Neurochemistry. 31: 283-7. PMID 97369 DOI: 10.1111/J.1471-4159.1978.Tb12461.X  0.354
1975 Lees MB, Chan DS. Proteolytic digestion of bovine brain white matter proteolipid. Journal of Neurochemistry. 25: 595-600. PMID 172604 DOI: 10.1111/J.1471-4159.1975.Tb04373.X  0.364
1974 Chan DS, Lees MB. Gel electrophoresis studies of bovine brain white matter proteolipid and myelin proteins. Biochemistry. 13: 2704-12. PMID 4858810 DOI: 10.1021/Bi00710A008  0.478
1974 Lees MB, Paxman SA. Myelin proteins from different regions of the central nervous system. Journal of Neurochemistry. 23: 825-31. PMID 4372322 DOI: 10.1111/J.1471-4159.1974.Tb04409.X  0.462
1973 Whikehart DR, Lees MB. Amino- and carboxyl-terminal amino acids of proteolipid proteins. Journal of Neurochemistry. 20: 1303-15. PMID 4716827 DOI: 10.1111/J.1471-4159.1973.Tb00242.X  0.413
1973 Lees MB, Paxman SA. Letters: Amino acid composition of myelin proteins recovered from polyacrylamide gels. Journal of Neurochemistry. 21: 1031-4. PMID 4127827 DOI: 10.1111/J.1471-4159.1973.Tb07553.X  0.493
1972 Lees MB, Paxman S. Modification of the Lowry procedure for the analysis of proteolipid protein. Analytical Biochemistry. 47: 184-92. PMID 5031110 DOI: 10.1016/0003-2697(72)90291-6  0.402
1968 Lees MB. Effect of ion removal on the solubility of rat brain proteins in chloroform-methanol mixtures. Journal of Neurochemistry. 15: 153-9. PMID 5638612 DOI: 10.1111/J.1471-4159.1968.Tb06190.X  0.354
1964 LEES MB, CARR S, FOLCH J. PURIFICATION OF BOVINE BRAIN WHITE MATTER PROTEOLIPIDS BY DIALYSIS IN ORGANIC SOLVENTS. Biochimica Et Biophysica Acta. 84: 464-6. PMID 14230822 DOI: 10.1016/0926-6542(64)90012-5  0.312
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