Wendy J. Lynch - Publications

University of Virginia, Charlottesville, VA 
Drug addiction, sex differences

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bakhti-Suroosh A, Towers EB, Lynch WJ. A buprenorphine-validated rat model of opioid use disorder optimized to study sex differences in vulnerability to relapse. Psychopharmacology. PMID 33404740 DOI: 10.1007/s00213-020-05750-2  0.36
2020 Lynch WJ, Bakhti-Suroosh A, Abel JM, Davis C. Shifts in the neurobiological mechanisms motivating cocaine use with the development of an addiction-like phenotype in male rats. Psychopharmacology. PMID 33241478 DOI: 10.1007/s00213-020-05732-4  0.36
2019 Bakhti-Suroosh A, Nesil T, Lynch WJ. Tamoxifen Blocks the Development of Motivational Features of an Addiction-Like Phenotype in Female Rats. Frontiers in Behavioral Neuroscience. 13: 253. PMID 31780909 DOI: 10.3389/fnbeh.2019.00253  0.36
2019 Abel JM, Nesil T, Bakhti-Suroosh A, Grant PA, Lynch WJ. Mechanisms underlying the efficacy of exercise as an intervention for cocaine relapse: a focus on mGlu5 in the dorsal medial prefrontal cortex. Psychopharmacology. PMID 31161451 DOI: 10.1007/s00213-019-05208-0  0.36
2019 Sanchez V, Bakhti-Suroosh A, Chen A, Brunzell DH, Erisir A, Lynch WJ. Exercise during Abstinence Normalizes Ultrastructural Synaptic Plasticity Associated with Nicotine-Seeking following Extended Access Self-Administration. The European Journal of Neuroscience. PMID 30888721 DOI: 10.1111/ejn.14408  0.56
2018 Nesil T, Narmeen S, Bakhti-Suroosh A, Lynch WJ. Effect of menthol on nicotine intake and relapse vulnerability in a rat model of concurrent intravenous menthol/nicotine self-administration. Psychopharmacology. PMID 30483833 DOI: 10.1007/s00213-018-5128-9  0.36
2017 Lynch WJ, Tan L, Narmeen S, Beiter R, Brunzell DH. Exercise or saccharin during abstinence block estrus-induced increases in nicotine-seeking. Physiology & Behavior. PMID 29080668 DOI: 10.1016/j.physbeh.2017.10.026  0.56
2016 Strickland JC, Abel JM, Lacy RT, Beckmann JS, Witte MA, Lynch WJ, Smith MA. The effects of resistance exercise on cocaine self-administration, muscle hypertrophy, and BDNF expression in the nucleus accumbens. Drug and Alcohol Dependence. PMID 27137405 DOI: 10.1016/j.drugalcdep.2016.04.019  1
2015 Sanchez V, Lycas MD, Lynch WJ, Brunzell DH. Wheel running exercise attenuates vulnerability to self-administer nicotine in rats. Drug and Alcohol Dependence. 156: 193-8. PMID 26433561 DOI: 10.1016/j.drugalcdep.2015.09.022  1
2015 Moore CF, Lynch WJ. Alcohol preferring (P) rats as a model for examining sex differences in alcohol use disorder and its treatment. Pharmacology, Biochemistry, and Behavior. 132: 1-9. PMID 25712173 DOI: 10.1016/j.pbb.2015.02.014  1
2015 Doyle SE, Feng H, Garber G, Menaker M, Lynch WJ. Effects of circadian disruption on methamphetamine consumption in methamphetamine-exposed rats. Psychopharmacology. 232: 2169-79. PMID 25543849 DOI: 10.1007/s00213-014-3845-2  1
2014 Doyle SE, Ramôa C, Garber G, Newman J, Toor Z, Lynch WJ. A shift in the role of glutamatergic signaling in the nucleus accumbens core with the development of an addicted phenotype. Biological Psychiatry. 76: 810-5. PMID 24629536 DOI: 10.1016/j.biopsych.2014.02.005  1
2014 Moore CF, Lycas MD, Bond CW, Johnson BA, Lynch WJ. Acute and chronic administration of a low-dose combination of topiramate and ondansetron reduces ethanol's reinforcing effects in male alcohol preferring (P) rats. Experimental and Clinical Psychopharmacology. 22: 35-42. PMID 24490709 DOI: 10.1037/a0035215  1
2014 Peterson AB, Hivick DP, Lynch WJ. Dose-dependent effectiveness of wheel running to attenuate cocaine-seeking: impact of sex and estrous cycle in rats. Psychopharmacology. 231: 2661-70. PMID 24464528 DOI: 10.1007/s00213-014-3437-1  1
2014 Sanchez V, Moore CF, Brunzell DH, Lynch WJ. Sex differences in the effect of wheel running on subsequent nicotine-seeking in a rat adolescent-onset self-administration model. Psychopharmacology. 231: 1753-62. PMID 24271035 DOI: 10.1007/s00213-013-3359-3  1
2014 Moore CF, Protzuk OA, Johnson BA, Lynch WJ. The efficacy of a low dose combination of topiramate and naltrexone on ethanol reinforcement and consumption in rat models. Pharmacology, Biochemistry, and Behavior. 116: 107-15. PMID 24252444 DOI: 10.1016/j.pbb.2013.11.013  1
2014 Ramôa CP, Doyle SE, Lycas MD, Chernau AK, Lynch WJ. Diminished role of dopamine D1-receptor signaling with the development of an addicted phenotype in rats. Biological Psychiatry. 76: 8-14. PMID 24199666 DOI: 10.1016/j.biopsych.2013.09.028  1
2014 Peterson AB, Abel JM, Lynch WJ. Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. Psychopharmacology. 231: 1305-14. PMID 24173624 DOI: 10.1007/s00213-013-3321-4  1
2013 Lynch WJ, Peterson AB, Sanchez V, Abel J, Smith MA. Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis. Neuroscience and Biobehavioral Reviews. 37: 1622-44. PMID 23806439 DOI: 10.1016/j.neubiorev.2013.06.011  1
2013 Ramôa CP, Doyle SE, Naim DW, Lynch WJ. Estradiol as a mechanism for sex differences in the development of an addicted phenotype following extended access cocaine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1698-705. PMID 23481437 DOI: 10.1038/npp.2013.68  1
2013 Sanchez V, Moore CF, Brunzell DH, Lynch WJ. Effect of wheel-running during abstinence on subsequent nicotine-seeking in rats. Psychopharmacology. 227: 403-11. PMID 23371488 DOI: 10.1007/s00213-012-2964-x  1
2012 Doyle SE, Breslin FJ, Rieger JM, Beauglehole A, Lynch WJ. Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats. Pharmacology, Biochemistry, and Behavior. 102: 257-63. PMID 22579716 DOI: 10.1016/j.pbb.2012.05.001  1
2011 Smith MA, Lynch WJ. Exercise as a potential treatment for drug abuse: evidence from preclinical studies. Frontiers in Psychiatry. 2: 82. PMID 22347866 DOI: 10.3389/fpsyt.2011.00082  1
2011 Lynch WJ, Bond C, Breslin FJ, Johnson BA. Severity of drinking as a predictor of efficacy of the combination of ondansetron and topiramate in rat models of ethanol consumption and relapse. Psychopharmacology. 217: 3-12. PMID 21424693 DOI: 10.1007/s00213-011-2253-0  1
2010 Lynch WJ, Sofuoglu M. Role of progesterone in nicotine addiction: evidence from initiation to relapse. Experimental and Clinical Psychopharmacology. 18: 451-61. PMID 21186920 DOI: 10.1037/a0021265  1
2010 Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biological Psychiatry. 68: 774-7. PMID 20692647 DOI: 10.1016/j.biopsych.2010.06.022  1
2010 Lynch WJ, Nicholson KL, Dance ME, Morgan RW, Foley PL. Animal models of substance abuse and addiction: implications for science, animal welfare, and society. Comparative Medicine. 60: 177-88. PMID 20579432  1
2010 Abdolahi A, Acosta G, Breslin FJ, Hemby SE, Lynch WJ. Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex. The European Journal of Neuroscience. 31: 733-41. PMID 20384816 DOI: 10.1111/j.1460-9568.2010.07114.x  1
2010 Angarita GA, Pittman B, Gueorguieva R, Kalayasiri R, Lynch WJ, Sughondhabirom A, Morgan PT, Malison RT. Regulation of cocaine self-administration in humans: lack of evidence for loading and maintenance phases. Pharmacology, Biochemistry, and Behavior. 95: 51-5. PMID 20005893 DOI: 10.1016/j.pbb.2009.12.005  1
2010 Breslin FJ, Johnson BA, Lynch WJ. Effect of topiramate treatment on ethanol consumption in rats. Psychopharmacology. 207: 529-34. PMID 19823810 DOI: 10.1007/s00213-009-1683-4  1
2009 Lynch WJ. Sex and ovarian hormones influence vulnerability and motivation for nicotine during adolescence in rats. Pharmacology, Biochemistry, and Behavior. 94: 43-50. PMID 19619575 DOI: 10.1016/j.pbb.2009.07.004  1
2008 Lynch WJ, Kalayasiri R, Sughondhabirom A, Pittman B, Coric V, Morgan PT, Malison RT. Subjective responses and cardiovascular effects of self-administered cocaine in cocaine-abusing men and women. Addiction Biology. 13: 403-10. PMID 18782384 DOI: 10.1111/j.1369-1600.2008.00115.x  1
2008 Lynch WJ, Girgenti MJ, Breslin FJ, Newton SS, Taylor JR. Gene profiling the response to repeated cocaine self-administration in dorsal striatum: a focus on circadian genes. Brain Research. 1213: 166-77. PMID 18452895 DOI: 10.1016/j.brainres.2008.02.106  1
2008 Lynch WJ. Acquisition and maintenance of cocaine self-administration in adolescent rats: effects of sex and gonadal hormones. Psychopharmacology. 197: 237-46. PMID 18066534 DOI: 10.1007/s00213-007-1028-0  1
2007 Taylor JR, Lynch WJ, Sanchez H, Olausson P, Nestler EJ, Bibb JA. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 104: 4147-52. PMID 17360491 DOI: 10.1073/pnas.0610288104  1
2007 Lynch WJ, Kiraly DD, Caldarone BJ, Picciotto MR, Taylor JR. Effect of cocaine self-administration on striatal PKA-regulated signaling in male and female rats. Psychopharmacology. 191: 263-71. PMID 17180335 DOI: 10.1007/s00213-006-0656-0  1
2007 Kalayasiri R, Sughondhabirom A, Gueorguieva R, Coric V, Lynch WJ, Lappalainen J, Gelernter J, Cubells JF, Malison RT. Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration. Biological Psychiatry. 61: 1310-3. PMID 17157269 DOI: 10.1016/j.biopsych.2006.08.012  1
2006 Ait-Daoud N, Lynch WJ, Penberthy JK, Breland AB, Marzani-Nissen GR, Johnson BA. Treating smoking dependence in depressed alcoholics. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 29: 213-20. PMID 17373412  1
2006 Kalayasiri R, Sughondhabirom A, Gueorguieva R, Coric V, Lynch WJ, Morgan PT, Cubells JF, Malison RT. Self-reported paranoia during laboratory "binge" cocaine self-administration in humans. Pharmacology, Biochemistry, and Behavior. 83: 249-56. PMID 16549106 DOI: 10.1016/j.pbb.2006.02.005  1
2006 Lynch WJ, Sughondhabirom A, Pittman B, Gueorguieva R, Kalayasiri R, Joshua D, Morgan P, Coric V, Malison RT. A paradigm to investigate the regulation of cocaine self-administration in human cocaine users: a randomized trial. Psychopharmacology. 185: 306-14. PMID 16521032 DOI: 10.1007/s00213-006-0323-5  1
2006 Lynch WJ. Sex differences in vulnerability to drug self-administration. Experimental and Clinical Psychopharmacology. 14: 34-41. PMID 16503703 DOI: 10.1037/1064-1297.14.1.34  1
2005 Lynch WJ, Taylor JR. Persistent changes in motivation to self-administer cocaine following modulation of cyclic AMP-dependent protein kinase A (PKA) activity in the nucleus accumbens. The European Journal of Neuroscience. 22: 1214-20. PMID 16176364 DOI: 10.1111/j.1460-9568.2005.04305.x  1
2005 Sughondhabirom A, Jain D, Gueorguieva R, Coric V, Berman R, Lynch WJ, Self D, Jatlow P, Malison RT. A paradigm to investigate the self-regulation of cocaine administration in humans. Psychopharmacology. 180: 436-46. PMID 15726333 DOI: 10.1007/s00213-005-2192-8  1
2005 Lynch WJ, Taylor JR. Decreased motivation following cocaine self-administration under extended access conditions: effects of sex and ovarian hormones. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 927-35. PMID 15647749 DOI: 10.1038/sj.npp.1300656  1
2005 Lynch WJ, Mangini LD, Taylor JR. Neonatal isolation stress potentiates cocaine seeking behavior in adult male and female rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 322-9. PMID 15508022 DOI: 10.1038/sj.npp.1300594  1
2005 Hart CL, Lynch WJ. Developing pharmacotherapies for cannabis and cocaine use disorders Current Neuropharmacology. 3: 95-114. DOI: 10.2174/1570159053586726  1
2004 Lynch WJ, Maciejewski PK, Potenza MN. Psychiatric correlates of gambling in adolescents and young adults grouped by age at gambling onset. Archives of General Psychiatry. 61: 1116-22. PMID 15520359 DOI: 10.1001/archpsyc.61.11.1116  1
2004 Carroll ME, Lynch WJ, Roth ME, Morgan AD, Cosgrove KP. Sex and estrogen influence drug abuse. Trends in Pharmacological Sciences. 25: 273-9. PMID 15120494 DOI: 10.1016/j.tips.2004.03.011  1
2004 Lynch WJ, Taylor JR. Sex differences in the behavioral effects of 24-h/day access to cocaine under a discrete trial procedure. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 943-51. PMID 14872204 DOI: 10.1038/sj.npp.1300389  1
2004 Lynch WJ, Roberts DC. Effects of cocaine self-administration on food-reinforced responding using a discrete trial procedure in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 669-75. PMID 14694351 DOI: 10.1038/sj.npp.1300363  1
2002 Freeman WM, Brebner K, Patel KM, Lynch WJ, Roberts DC, Vrana KE. Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression. Neurochemical Research. 27: 1181-92. PMID 12462416 DOI: 10.1023/A:1020929526688  1
2002 Lynch WJ, Roth ME, Carroll ME. Biological basis of sex differences in drug abuse: preclinical and clinical studies. Psychopharmacology. 164: 121-37. PMID 12404074 DOI: 10.1007/s00213-002-1183-2  1
2002 Morgan D, Brebner K, Lynch WJ, Roberts DC. Increases in the reinforcing efficacy of cocaine after particular histories of reinforcement. Behavioural Pharmacology. 13: 389-96. PMID 12394415  1
2002 Roberts DC, Brebner K, Vincler M, Lynch WJ. Patterns of cocaine self-administration in rats produced by various access conditions under a discrete trials procedure. Drug and Alcohol Dependence. 67: 291-9. PMID 12127200 DOI: 10.1016/S0376-8716(02)00083-2  1
2002 Freeman WM, Brebner K, Lynch WJ, Patel KM, Robertson DJ, Roberts DC, Vrana KE. Changes in rat frontal cortex gene expression following chronic cocaine. Brain Research. Molecular Brain Research. 104: 11-20. PMID 12117546 DOI: 10.1016/S0169-328X(02)00197-3  1
2002 Carroll ME, Morgan AD, Lynch WJ, Campbell UC, Dess NK. Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences. Psychopharmacology. 161: 304-13. PMID 12021834 DOI: 10.1007/s00213-002-1030-5  1
2001 Freeman WM, Brebner K, Lynch WJ, Robertson DJ, Roberts DC, Vrana KE. Cocaine-responsive gene expression changes in rat hippocampus. Neuroscience. 108: 371-80. PMID 11738252 DOI: 10.1016/S0306-4522(01)00432-8  1
2001 Lynch WJ, Roth ME, Mickelberg JL, Carroll ME. Role of estrogen in the acquisition of intravenously self-administered cocaine in female rats. Pharmacology, Biochemistry, and Behavior. 68: 641-6. PMID 11526960 DOI: 10.1016/S0091-3057(01)00455-5  1
2001 Lynch WJ, Carroll ME. Regulation of drug intake. Experimental and Clinical Psychopharmacology. 9: 131-43. PMID 11518086 DOI: 10.1037/1064-1297.9.2.131  1
2001 Lynch WJ, Carroll ME. Regulation of drug intake: Reply to Killeen and Reilly (2001), Madden (2001), Norman and Tsibulsky (2001), Woods (2001), and Young (2001) Experimental and Clinical Psychopharmacology. 9: 160-162. DOI: 10.1037/1064-1297.9.2.160  1
2000 Lynch WJ, Arizzi MN, Carroll ME. Effects of sex and the estrous cycle on regulation of intravenously self-administered cocaine in rats. Psychopharmacology. 152: 132-9. PMID 11057516 DOI: 10.1007/s002130000488  1
2000 Lynch WJ, Carroll ME. Reinstatement of cocaine self-administration in rats: sex differences. Psychopharmacology. 148: 196-200. PMID 10663435  1
1999 Lynch WJ, Kushner MG, Rawleigh JM, Fiszdon J, Carroll ME. The effects of restraint stress on voluntary ethanol consumption in rats. Experimental and Clinical Psychopharmacology. 7: 318-23. PMID 10609966 DOI: 10.1037//1064-1297.7.4.318  1
1999 Lynch WJ, Carroll ME. Regulation of intravenously self-administered nicotine in rats. Experimental and Clinical Psychopharmacology. 7: 198-207. PMID 10472507 DOI: 10.1037/1064-1297.7.3.198  1
1999 Lynch WJ, Carroll ME. Sex differences in the acquisition of intravenously self-administered cocaine and heroin in rats. Psychopharmacology. 144: 77-82. PMID 10379627 DOI: 10.1007/s002130050979  1
1998 LaBounty LP, Lynch WJ, Carroll ME. Ethanol consumption in rats when dose size is under subject control. Experimental and Clinical Psychopharmacology. 6: 347-52. PMID 9861548 DOI: 10.1037/1064-1297.6.4.347  1
1998 Lynch WJ, Heaser WA, Carroll ME. Effects of amphetamine, butorphanol, and morphine pretreatment on the maintenance and reinstatement of cocaine-reinforced responding. Experimental and Clinical Psychopharmacology. 6: 255-63. PMID 9725109 DOI: 10.1037//1064-1297.6.3.255  1
1998 Lynch WJ, LaBounty LP, Carroll ME. A novel paradigm to investigate regulation of drug intake in rats self-administering cocaine or heroin intravenously. Experimental and Clinical Psychopharmacology. 6: 22-31. PMID 9526143 DOI: 10.1037/1064-1297.6.1.22  1
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