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Eliezer Masliah, MD, National Autonomous University of Mexico 1983 - Publications

Affiliations: 
Pathology and Medicine University of California, San Diego, La Jolla, CA 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=7
Website:
http://molpath.ucsd.edu/faculty/Masliah.shtml
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Year Citation  Score
2021 Ho G, Ali A, Takamatsu Y, Wada R, Masliah E, Hashimoto M. Diabetes, inflammation, and the adiponectin paradox: therapeutic targets in SARS-CoV-2. Drug Discovery Today. PMID 33775925 DOI: 10.1016/j.drudis.2021.03.013  0.36
2021 Wei J, Takamatsu Y, Wada R, Fujita M, Ho G, Masliah E, Hashimoto M. Therapeutic Potential of αS Evolvability for Neuropathic Gaucher Disease. Biomolecules. 11. PMID 33672048 DOI: 10.3390/biom11020289  0.36
2021 Kim C, Kwon S, Iba M, Spencer B, Rockenstein E, Mante M, Adame A, Shin SJ, Fields JA, Rissman RA, Lee SJ, Masliah E. Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells. Experimental & Molecular Medicine. PMID 33594256 DOI: 10.1038/s12276-021-00562-6  0.52
2021 Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, ... ... Masliah E, et al. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. PMID 33589841 DOI: 10.1038/s41588-021-00785-3  0.48
2021 Ngolab J, Canchi S, Rasool S, Elmaarouf A, Thomas K, Sarsoza F, Grundman J, Mante M, Florio J, Nandankar N, Korouri S, Zago W, Masliah E, Rissman RA. Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2. Neurobiology of Disease. 105277. PMID 33516874 DOI: 10.1016/j.nbd.2021.105277  0.44
2020 Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, ... ... Masliah E, et al. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. Journal of Neuropathology and Experimental Neurology. PMID 33367843 DOI: 10.1093/jnen/nlaa153  0.68
2020 Nakamura T, Oh CK, Liao L, Zhang X, Lopez KM, Gibbs D, Deal AK, Scott HR, Spencer B, Masliah E, Rissman RA, Yates JR, Lipton SA. Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease. Science (New York, N.Y.). PMID 33273062 DOI: 10.1126/science.aaw0843  0.52
2020 Ho G, Takamatsu Y, Wada R, Sugama S, Waragai M, Takenouchi T, Masliah E, Hashimoto M. Connecting Alzheimer's Disease With Diabetes Mellitus Through Amyloidogenic Evolvability. Frontiers in Aging Neuroscience. 12: 576192. PMID 33192467 DOI: 10.3389/fnagi.2020.576192  0.36
2020 Hur JY, Frost GR, Wu X, Crump C, Pan SJ, Wong E, Barros M, Li T, Nie P, Zhai Y, Wang JC, Tcw J, Guo L, McKenzie A, Ming C, ... ... Masliah E, et al. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease. Nature. PMID 32879487 DOI: 10.1038/s41586-020-2681-2  0.44
2020 Saez-Atienzar S, Masliah E. Author Correction: Cellular senescence and Alzheimer disease: the egg and the chicken scenario. Nature Reviews. Neuroscience. PMID 32792667 DOI: 10.1038/s41583-020-0366-3  0.48
2020 Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology. Acta Neuropathologica Communications. 8: 123. PMID 32753049 DOI: 10.1186/s40478-020-01006-4  0.52
2020 Iba M, Kim C, Sallin M, Kwon S, Verma A, Overk C, Rissman RA, Sen R, Sen JM, Masliah E. Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models. Journal of Neuroinflammation. 17: 214. PMID 32680537 DOI: 10.1186/s12974-020-01888-0  0.44
2020 Waragai M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Adiponectin Paradox as a Therapeutic Target in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32623396 DOI: 10.3233/JAD-200416  0.36
2020 Saez-Atienzar S, Masliah E. Cellular senescence and Alzheimer disease: the egg and the chicken scenario. Nature Reviews. Neuroscience. PMID 32601397 DOI: 10.1038/s41583-020-0325-z  0.48
2020 Ghatak S, Dolatabadi N, Gao R, Wu Y, Scott H, Trudler D, Sultan A, Ambasudhan R, Nakamura T, Masliah E, Talantova M, Voytek B, Lipton SA. NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. Molecular Psychiatry. PMID 32467645 DOI: 10.1038/s41380-020-0776-7  0.36
2020 Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Waragai M, Masliah E, Takenouchi T. Understanding Creutzfeldt-Jackob disease from a viewpoint of amyloidogenic evolvability. Prion. 14: 1-8. PMID 32375593 DOI: 10.1080/19336896.2020.1761514  0.36
2020 Iba M, Kim C, Florio J, Mante M, Adame A, Rockenstein E, Kwon S, Rissman R, Masliah E. Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models. Frontiers in Neuroscience. 14: 286. PMID 32296304 DOI: 10.3389/fnins.2020.00286  0.52
2020 Waragai M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability? Frontiers in Endocrinology. 11: 108. PMID 32194507 DOI: 10.3389/fendo.2020.00108  0.36
2020 Marschallinger J, Altendorfer B, Rockenstein E, Holztrattner M, Garnweidner-Raith J, Pillichshammer N, Leister I, Hutter-Paier B, Strempfl K, Unger MS, Chishty M, Felder T, Johnson M, Attems J, Masliah E, et al. The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 32072462 DOI: 10.1007/s13311-020-00836-3  0.52
2020 Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, ... ... Masliah E, et al. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications. 8: 5. PMID 31996268 DOI: 10.1186/s40478-020-0879-z  0.44
2019 Hodgson R, Kennedy BK, Masliah E, Scearce-Levie K, Tate B, Venkateswaran A, Braithwaite SP. AGING: THERAPEUTICS FOR A HEALTHY FUTURE. Neuroscience and Biobehavioral Reviews. PMID 31783058 DOI: 10.1016/j.neubiorev.2019.11.021  0.36
2019 Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Waragai M, Masliah E. Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease. Journal of Parkinson's Disease. PMID 31524179 DOI: 10.3233/JPD-191675  0.36
2019 Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, ... ... Masliah E, et al. Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo. Neurobiology of Disease. 104582. PMID 31445162 DOI: 10.1016/j.nbd.2019.104582  0.52
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Masliah E, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.4
2019 Mandler M, Rockenstein E, Overk C, Mante M, Florio J, Adame A, Kim C, Santic R, Schneeberger A, Mattner F, Schmidhuber S, Galabova G, Spencer B, Masliah E, Rissman RA. Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31378574 DOI: 10.1016/j.jalz.2019.02.002  0.52
2019 He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, ... ... Masliah E, et al. NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology. Cellular & Molecular Immunology. PMID 31320730 DOI: 10.1038/s41423-019-0260-y  0.64
2019 Gerez JA, Prymaczok NC, Rockenstein E, Herrmann US, Schwarz P, Adame A, Enchev RI, Courtheoux T, Boersema PJ, Riek R, Peter M, Aguzzi A, Masliah E, Picotti P. A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology. Science Translational Medicine. 11. PMID 31167929 DOI: 10.1126/scitranslmed.aau6722  0.52
2019 Shanbhag NM, Evans MD, Mao W, Nana AL, Seeley WW, Adame A, Rissman RA, Masliah E, Mucke L. Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease. Acta Neuropathologica Communications. 7: 77. PMID 31101070 DOI: 10.1186/s40478-019-0723-5  0.44
2019 Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, ... ... Masliah E, et al. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease. PMID 30953760 DOI: 10.1016/j.nbd.2019.04.004  0.44
2019 Okamoto SI, Prikhodko O, Pina-Crespo J, Adame A, McKercher SR, Brill LM, Nakanishi N, Oh CK, Nakamura T, Masliah E, Lipton SA. NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model. Neurobiology of Disease. PMID 30928642 DOI: 10.1016/j.nbd.2019.03.029  0.36
2019 Spencer B, Trinh I, Rockenstein E, Mante M, Florio J, Adame A, El-Agnaf OMA, Kim C, Masliah E, Rissman RA. Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease. Neurobiology of Disease. PMID 30849508 DOI: 10.1016/j.nbd.2019.03.001  0.52
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Masliah E, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.4
2019 Mackiewicz MM, Overk C, Achim CL, Masliah E. Pathogenesis of age-related HIV neurodegeneration. Journal of Neurovirology. PMID 30790184 DOI: 10.1007/s13365-019-00728-z  0.36
2019 Takamatsu Y, Ho G, Waragai M, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Transgenerational Interaction of Alzheimer's Disease with Schizophrenia through Amyloid Evolvability. Journal of Alzheimer's Disease : Jad. PMID 30741673 DOI: 10.3233/JAD-180986  0.36
2019 Snow AD, Castillo GM, Nguyen BP, Choi PY, Cummings JA, Cam J, Hu Q, Lake T, Pan W, Kastin AJ, Kirschner DA, Wood SG, Rockenstein E, Masliah E, Lorimer S, et al. The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles. Scientific Reports. 9: 561. PMID 30728442 DOI: 10.1038/s41598-019-38645-0  0.52
2018 Takamatsu Y, Fujita M, Ho GJ, Wada R, Sugama S, Takenouchi T, Waragai M, Masliah E, Hashimoto M. Motor and Nonmotor Symptoms of Parkinson's Disease: Antagonistic Pleiotropy Phenomena Derived from -Synuclein Evolvability? Parkinson's Disease. 2018: 5789424. PMID 30595837 DOI: 10.1155/2018/5789424  0.36
2018 Hassen GW, Kesner L, Stracher A, Shulman A, Rockenstein E, Mante M, Adame A, Overk C, Rissman RA, Masliah E. Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies. Scientific Reports. 8: 18083. PMID 30591714 DOI: 10.1038/s41598-018-35729-1  0.52
2018 Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, ... ... Masliah E, et al. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiology of Aging. PMID 30448004 DOI: 10.1016/j.neurobiolaging.2018.10.019  0.44
2018 Price DL, Koike MA, Khan A, Wrasidlo W, Rockenstein E, Masliah E, Bonhaus D. The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease. Scientific Reports. 8: 16165. PMID 30385782 DOI: 10.1038/s41598-018-34490-9  0.52
2018 Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Waragai M. Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability. Journal of Huntington's Disease. PMID 30372687 DOI: 10.3233/JHD-180309  0.36
2018 Fields JA, Spencer B, Swinton M, Qvale EM, Marquine MJ, Alexeeva A, Gough S, Soontornniyomkij B, Valera E, Masliah E, Achim CL, Desplats P. Alterations in brain TREM2 and Amyloid-β levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy. Journal of Neurochemistry. PMID 30152135 DOI: 10.1111/jnc.14582  0.36
2018 Bae EJ, Kim DK, Kim C, Mante M, Adame A, Rockenstein E, Ulusoy A, Klinkenberg M, Jeong GR, Bae JR, Lee C, Lee HJ, Lee BD, Di Monte DA, Masliah E, et al. LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation. Nature Communications. 9: 3465. PMID 30150626 DOI: 10.1038/s41467-018-05958-z  0.52
2018 Chen XQ, Fang F, Florio JB, Rockenstein E, Masliah E, Mobley WC, Rissman RA, Wu C. TRiC enhances retrograde axonal transport by modulating tau phosphorylation. Traffic (Copenhagen, Denmark). PMID 30120810 DOI: 10.1111/tra.12610  0.52
2018 Hashimoto M, Ho G, Takamatsu Y, Shimizu Y, Sugama S, Takenouchi T, Waragai M, Masliah E. Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates. Journal of Parkinson's Disease. PMID 30010144 DOI: 10.3233/JPD-181365  0.36
2018 Spencer B, Brüschweiler S, Sealey-Cardona M, Rockenstein E, Adame A, Florio J, Mante M, Trinh I, Rissman RA, Konrat R, Masliah E. Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders. Acta Neuropathologica. 136: 69-87. PMID 29934874 DOI: 10.1007/s00401-018-1869-0  0.52
2018 Waragai M, Ho G, Takamatsu Y, Shimizu Y, Sugino H, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Dual-therapy strategy for modification of adiponectin receptor signaling in aging-associated chronic diseases. Drug Discovery Today. PMID 29747002 DOI: 10.1016/j.drudis.2018.05.009  0.36
2018 Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Roßner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29630865 DOI: 10.1016/j.jalz.2018.02.017  0.52
2018 Tulloch J, Leong L, Chen S, Keene CD, Millard SP, Shutes-David A, Lopez OL, Kofler J, Kaye JA, Woltjer R, Nelson PT, Neltner JH, Jicha GA, Galasko D, Masliah E, et al. APOE DNA methylation is altered in Lewy body dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29544979 DOI: 10.1016/j.jalz.2018.02.005  0.44
2018 Hashimoto M, Ho G, Sugama S, Takamatsu Y, Shimizu Y, Takenouchi T, Waragai M, Masliah E. Evolvability of Amyloidogenic Proteins in Human Brain. Journal of Alzheimer's Disease : Jad. 62: 73-83. PMID 29439348 DOI: 10.3233/JAD-170894  0.36
2018 Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. Journal of Alzheimer's Disease : Jad. 61: 1201-1219. PMID 29332037 DOI: 10.3233/JAD-170388  0.52
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, ... ... Masliah E, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.44
2017 Rockenstein E, Ostroff G, Dikengil F, Rus F, Mante M, Florio J, Adame A, Trinh I, Kim C, Overk C, Masliah E, Rissman RA. Combined active humoral and cellular immunization approaches for the treatment of Synucleinopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29246926 DOI: 10.1523/JNEUROSCI.1170-17.2017  0.52
2017 Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Buzás EI, Schlötzer-Schrehardt U, Marcus K, ... ... Masliah E, et al. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy. 1-61. PMID 29198173 DOI: 10.1080/15548627.2017.1395992  0.52
2017 Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, et al. Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. Cell Reports. 21: 2614-2627. PMID 29186695 DOI: 10.1016/j.celrep.2017.11.009  0.8
2017 Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity. Nature Communications. 8: 1472. PMID 29133892 DOI: 10.1038/s41467-017-01799-4  0.4
2017 Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, ... ... Masliah E, et al. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nature Communications. 8: 1488. PMID 29133852 DOI: 10.1038/s41467-017-01563-8  0.44
2017 Regensburger M, Schreglmann SR, Stoll S, Rockenstein E, Loskarn S, Xiang W, Masliah E, Winner B. Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice. Brain Structure & Function. PMID 29124353 DOI: 10.1007/s00429-017-1561-5  0.52
2017 Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration. The Journal of Experimental Medicine. PMID 29114064 DOI: 10.1084/jem.20171413  0.4
2017 Valera E, Spencer B, Mott J, Trejo M, Adame A, Mante M, Rockenstein E, Troncoso JC, Beach TG, Masliah E, Desplats P. MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Frontiers in Molecular Neuroscience. 10: 329. PMID 29089869 DOI: 10.3389/fnmol.2017.00329  0.52
2017 Overk C, Rockenstein E, Valera E, Stefanova N, Wenning G, Masliah E. Multiple system atrophy: experimental models and reality. Acta Neuropathologica. PMID 29058121 DOI: 10.1007/s00401-017-1772-0  0.52
2017 Waragai M, Ho G, Takamatsu Y, Sekiyama K, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Importance of adiponectin activity in the pathogenesis of Alzheimer's disease. Annals of Clinical and Translational Neurology. 4: 591-600. PMID 28812049 DOI: 10.1002/acn3.436  0.36
2017 Tallon C, Rockenstein E, Masliah E, Farah MH. Increased bace1 activity inhibits peripheral nerve regeneration after injury. Neurobiology of Disease. PMID 28687442 DOI: 10.1016/j.nbd.2017.07.003  0.52
2017 Fang F, Yang W, Florio JB, Rockenstein E, Spencer B, Orain XM, Dong SX, Li H, Chen X, Sung K, Rissman RA, Masliah E, Ding J, Wu C. Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease. Scientific Reports. 7: 3868. PMID 28634349 DOI: 10.1038/s41598-017-04232-4  0.52
2017 Reilly P, Winston CN, Baron K, Trejo M, Rockenstein EM, Akers JC, Kfoury N, Diamond M, Masliah E, Rissman RA, Yuan SH. Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation. Neurobiology of Disease. PMID 28610892 DOI: 10.1016/j.nbd.2017.06.005  0.44
2017 Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology. Acta Neuropathologica Communications. 5: 46. PMID 28599681 DOI: 10.1186/s40478-017-0445-5  0.52
2017 McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, ... ... Masliah E, et al. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. PMID 28592453 DOI: 10.1212/WNL.0000000000004058  0.44
2017 El-Agnaf O, Overk C, Rockenstein E, Mante M, Florio J, Adame A, Vaikath N, Majbour N, Lee SJ, Kim C, Masliah E, Rissman RA. Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy. Neurobiology of Disease. PMID 28476636 DOI: 10.1016/j.nbd.2017.05.002  0.52
2017 Bryant AK, Moore DJ, Burdo TH, Lakritz JR, Gouaux B, Soontornniyomkij V, Achim CL, Masliah E, Grant I, Levine AJ, Ellis RJ. Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection. Aids (London, England). PMID 28244955 DOI: 10.1097/QAD.0000000000001425  0.36
2017 Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. PMID 28111199 DOI: 10.1016/j.stem.2016.12.006  0.52
2017 Fields JA, Metcalf J, Overk C, Adame A, Spencer B, Wrasidlo W, Florio J, Rockenstein E, He JJ, Masliah E. The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration. Journal of Neurovirology. PMID 28105557 DOI: 10.1007/s13365-016-0502-z  0.52
2017 Spencer B, Valera E, Rockenstein E, Overk C, Mante M, Adame A, Zago W, Seubert P, Barbour R, Schenk D, Games D, Rissman RA, Masliah E. Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy. Acta Neuropathologica Communications. 5: 7. PMID 28086964 DOI: 10.1186/s40478-016-0410-8  0.52
2017 Valera E, Spencer B, Fields JA, Trinh I, Adame A, Mante M, Rockenstein E, Desplats P, Masliah E. Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy. Acta Neuropathologica Communications. 5: 2. PMID 28057080 DOI: 10.1186/s40478-016-0409-1  0.52
2016 Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and is Consistent with Spread of Pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28039370 DOI: 10.1523/JNEUROSCI.3047-16.2016  0.68
2016 Lipton SA, Rezaie T, Nutter A, Lopez KM, Parker J, Kosaka K, Satoh T, McKercher SR, Masliah E, Nakanishi N. Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models. Cell Death & Disease. 7: e2499. PMID 27906174 DOI: 10.1038/cddis.2016.389  0.36
2016 Cronin P, McCarthy MJ, Lim AS, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P. Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27883893 DOI: 10.1016/j.jalz.2016.10.003  0.44
2016 Sunico CR, Sultan A, Nakamura T, Dolatabadi N, Parker J, Shan B, Han X, Yates JR, Masliah E, Ambasudhan R, Nakanishi N, Lipton SA. Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821734 DOI: 10.1073/pnas.1608784113  0.36
2016 Chen SG, Stribinskis V, Rane MJ, Demuth DR, Gozal E, Roberts AM, Jagadapillai R, Liu R, Choe K, Shivakumar B, Son F, Jin S, Kerber R, Adame A, Masliah E, et al. Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans. Scientific Reports. 6: 34477. PMID 27708338 DOI: 10.1038/srep34477  0.48
2016 Wrasidlo W, Tsigelny IF, Price DL, Dutta G, Rockenstein E, Schwarz TC, Ledolter K, Bonhaus D, Paulino A, Eleuteri S, Skjevik ÅA, Kouznetsova VL, Spencer B, Desplats P, Gonzalez-Ruelas T, ... ... Masliah E, et al. A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease. Brain : a Journal of Neurology. PMID 27679481 DOI: 10.1093/brain/aww238  0.52
2016 Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, ... ... Masliah E, et al. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging. PMID 27666590 DOI: 10.1016/j.neurobiolaging.2016.08.023  0.44
2016 Spencer B, Williams S, Rockenstein E, Valera E, Xin W, Mante M, Florio J, Adame A, Masliah E, Sierks MR. α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease. Annals of Clinical and Translational Neurology. 3: 588-606. PMID 27606342 DOI: 10.1002/acn3.321  0.52
2016 Uhlirova H, Kılıç K, Tian P, Sakadžić S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, ... Masliah E, et al. The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 371. PMID 27574309 DOI: 10.1098/rstb.2015.0356  0.48
2016 Xu J, de Winter F, Farrokhi C, Rockenstein E, Mante M, Adame A, Cook J, Jin X, Masliah E, Lee KF. Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model. Scientific Reports. 6: 31692. PMID 27558862 DOI: 10.1038/srep31692  0.48
2016 Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/JCI80339  0.48
2016 Kim C, Lv G, Lee JS, Jung BC, Masuda-Suzukake M, Hong CS, Valera E, Lee HJ, Paik SR, Hasegawa M, Masliah E, Eliezer D, Lee SJ. Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril. Scientific Reports. 6: 30891. PMID 27488222 DOI: 10.1038/srep30891  0.48
2016 Spencer B, Desplats PA, Overk CR, Valera-Martin E, Rissman RA, Wu C, Mante M, Adame A, Florio J, Rockenstein E, Masliah E. Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7971-84. PMID 27466341 DOI: 10.1523/JNEUROSCI.0775-16.2016  0.52
2016 Winston CN, Goetzl EJ, Akers JC, Carter BS, Rockenstein EM, Galasko D, Masliah E, Rissman RA. Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile. Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 63-72. PMID 27408937 DOI: 10.1016/j.dadm.2016.04.001  0.44
2016 Price DL, Rockenstein E, Mante M, Adame A, Overk C, Spencer B, Duong-Polk KX, Bonhaus D, Lindsey J, Masliah E. Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson's Disease/Dementia with Lewy Bodies. Scientific Reports. 6: 29523. PMID 27389831 DOI: 10.1038/srep29523  0.52
2016 Uhlirova H, Kılıç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžić S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vanderberghe M, Cremonesi JA, Ferri CG, ... ... Masliah E, et al. Cell type specificity of neurovascular coupling in cerebral cortex. Elife. 5. PMID 27244241 DOI: 10.7554/eLife.14315  0.48
2016 Fields JA, Overk C, Adame A, Florio J, Mante M, Pineda A, Desplats P, Rockenstein E, Achim C, Masliah E. Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity. Journal of Neuroinflammation. 13: 120. PMID 27220536 DOI: 10.1186/s12974-016-0585-8  0.48
2016 Bharti AR, Woods SP, Ellis RJ, Cherner M, Rosario D, Potter M, Heaton RK, Everall IP, Masliah E, Grant I, Letendre SL. Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. Hiv/Aids (Auckland, N.Z.). 8: 93-9. PMID 27199571 DOI: 10.2147/HIV.S93306  0.48
2016 Rockenstein E, Clarke J, Viel C, Panarello N, Treleaven CM, Kim C, Spencer B, Adame A, Park H, Dodge JC, Cheng SH, Shihabuddin LS, Masliah E, Sardi SP. Glucocerebrosidase Modulates Cognitive and Motor Activities in Murine Models of Parkinson's Disease. Human Molecular Genetics. PMID 27126635 DOI: 10.1093/hmg/ddw124  0.52
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, ... ... Masliah E, et al. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 31. PMID 27112350 DOI: 10.1186/s13024-016-0095-2  0.48
2016 Soontornniyomkij V, Umlauf A, Soontornniyomkij B, Batki IB, Moore DJ, Masliah E, Achim CL. Lifetime methamphetamine dependence is associated with cerebral microgliosis in HIV-1-infected adults. Journal of Neurovirology. PMID 27098516 DOI: 10.1007/s13365-016-0441-8  0.48
2016 Waragai M, Adame A, Trinh I, Sekiyama K, Takamatsu Y, Une K, Masliah E, Hashimoto M. Possible Involvement of Adiponectin, the Anti-Diabetes Molecule, in the Pathogenesis of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27079710 DOI: DOI 10.3233/JAD-151116  0.36
2016 Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, ... ... Masliah E, et al. An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome. Plos One. 11: e0152471. PMID 27023444 DOI: 10.1371/journal.pone.0152471  0.48
2016 Avdoshina V, Fields JA, Castellano P, Dedoni S, Palchik G, Trejo M, Adame A, Rockenstein E, Eugenin E, Masliah E, Mocchetti I. The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons. Neurotoxicity Research. PMID 26936603 DOI: 10.1007/s12640-016-9608-6  0.48
2016 Maeda S, Djukic B, Taneja P, Yu GQ, Lo I, Davis A, Craft R, Guo W, Wang X, Kim D, Ponnusamy R, Gill TM, Masliah E, Mucke L. Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice. Embo Reports. PMID 26931567 DOI: 10.15252/embr.201541438  0.48
2016 Bachis A, Forcelli P, Masliah E, Campbell L, Mocchetti I. Expression of gp120 in mice evokes anxiety behavior: co-occurrence with increased dendritic spines and brain-derived neurotrophic factor in the amygdala. Brain, Behavior, and Immunity. PMID 26845379 DOI: 10.1016/j.bbi.2016.01.020  0.48
2016 Fares MB, Maco B, Oueslati A, Rockenstein E, Ninkina N, Buchman VL, Masliah E, Lashuel HA. Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 26839406 DOI: 10.1073/pnas.1512876113  0.48
2016 de Wilde MC, Overk CR, Sijben JW, Masliah E. Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26776762 DOI: 10.1016/j.jalz.2015.12.005  0.48
2016 Spencer B, Kim C, Gonzalez T, Bisquertt A, Patrick C, Rockenstein E, Adame A, Lee SJ, Desplats P, Masliah E. α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy Body disease. Human Molecular Genetics. PMID 26740557 DOI: 10.1093/hmg/ddv633  0.48
2016 Masliah E, Salmon DP. When Cognitive Decline Becomes Pathology: From Normal Aging to Alzheimer's Disease Genes, Environment and Alzheimer's Disease. 29-50. DOI: 10.1016/B978-0-12-802851-3.00002-4  0.48
2015 Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Moessler H, Masliah E. Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an α-Synuclein Transgenic Model of Parkinson's Disease. Journal of Experimental Neuroscience. 9: 131-40. PMID 27429559 DOI: 10.4137/JEN.S25521  0.52
2015 Levine AJ, Quach A, Moore DJ, Achim CL, Soontornniyomkij V, Masliah E, Singer EJ, Gelman B, Nemanim N, Horvath S. Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders. Journal of Neurovirology. PMID 26689571 DOI: 10.1007/s13365-015-0406-3  0.48
2015 Kim C, Ojo-Amaize E, Spencer B, Rockenstein E, Mante M, Desplats P, Wrasidlo W, Adame A, Nchekwube E, Oyemade O, Okogun J, Chan M, Cottam H, Masliah E. Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease. Journal of Neuroinflammation. 12: 236. PMID 26683203 DOI: 10.1186/s12974-015-0455-9  0.48
2015 Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ. Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. Journal of Neurovirology. PMID 26637429 DOI: 10.1007/s13365-015-0410-7  0.36
2015 Spencer B, Potkar R, Metcalf J, Trinh I, Adame A, Rockenstein E, Masliah E. Systemic CNS-targeted Delivery of NPY Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer's Disease. The Journal of Biological Chemistry. PMID 26620558 DOI: 10.1074/jbc.M115.678185  0.52
2015 Suberbielle E, Djukic B, Evans M, Kim DH, Taneja P, Wang X, Finucane M, Knox J, Ho K, Devidze N, Masliah E, Mucke L. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. Nature Communications. 6: 8897. PMID 26615780 DOI: 10.1038/ncomms9897  0.48
2015 Rockenstein E, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. Bmc Neuroscience. 16: 85. PMID 26611895 DOI: 10.1186/s12868-015-0218-7  0.48
2015 Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy AN, Ellis RJ, Letendre S, Grant I, Masliah E. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiology of Disease. PMID 26611103 DOI: 10.1016/j.nbd.2015.11.015  0.48
2015 Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA. Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26555315 DOI: 10.1016/j.jalz.2015.09.007  0.48
2015 Valera E, Spencer B, Masliah E. Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 26494242 DOI: 10.1007/s13311-015-0397-z  0.48
2015 Goldberg NR, Caesar J, Park A, Sedgh S, Finogenov G, Masliah E, Davis J, Blurton-Jones M. Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism. Stem Cell Reports. PMID 26489892 DOI: 10.1016/j.stemcr.2015.09.008  0.48
2015 Kim C, Rockenstein E, Spencer B, Kim HK, Adame A, Trejo M, Stafa K, Lee HJ, Lee SJ, Masliah E. Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy. Cell Reports. PMID 26489461 DOI: 10.1016/j.celrep.2015.09.044  0.48
2015 Gaffney PM, Witte C, Clifford DL, Imai DM, O'Brien TD, Trejo M, Liberta F, Annamalai K, Fändrich M, Masliah E, Munson L, Sigurdson CJ. Systemic Amyloid A Amyloidosis in Island Foxes (Urocyon littoralis): Severity and Risk Factors. Veterinary Pathology. PMID 26419399 DOI: 10.1177/0300985815604725  0.48
2015 Spencer B, Valera E, Rockenstein E, Trejo-Morales M, Adame A, Masliah E. A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy. Molecular Neurodegeneration. 10: 48. PMID 26394760 DOI: 10.1186/s13024-015-0043-6  0.48
2015 Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, ... ... Masliah E, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature Medicine. PMID 26390242 DOI: 10.1038/nm.3951  0.48
2015 Nakanishi N, Kang YJ, Tu S, McKercher SR, Masliah E, Lipton SA. Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model. Journal of Molecular Neuroscience : Mn. PMID 26374431 DOI: 10.1007/s12031-015-0651-1  0.48
2015 Overk CR, Rockenstein E, Florio J, Cheng Q, Masliah E. Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506. Neuroscience. 310: 549-60. PMID 26341908 DOI: 10.1016/j.neuroscience.2015.08.068  0.48
2015 Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, ... ... Masliah E, et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 87: 963-75. PMID 26335643 DOI: 10.1016/j.neuron.2015.08.020  0.48
2015 Tuszynski MH, Yang JH, Barba D, U HS, Bakay RA, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH. Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease. Jama Neurology. PMID 26302439 DOI: 10.1001/jamaneurol.2015.1807  0.48
2015 Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. Neuro-peptide treatment with Cerebrolysin improves the survival of neural stem cell grafts in an APP transgenic model of Alzheimer disease. Stem Cell Research. 15: 54-67. PMID 26209890 DOI: 10.1016/j.scr.2015.04.008  0.48
2015 Masliah E, Spencer B. Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 1324: 331-7. PMID 26202279 DOI: 10.1007/978-1-4939-2806-4_21  0.48
2015 Deusser J, Schmidt S, Ettle B, Plötz S, Huber S, Müller CP, Masliah E, Winkler J, Kohl Z. Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease. Journal of Neurochemistry. PMID 26201615 DOI: 10.1111/jnc.13253  0.48
2015 Salmon DP, Heindel WC, Hamilton JM, Vincent Filoteo J, Cidambi V, Hansen LA, Masliah E, Galasko D. Recognition memory span in autopsy-confirmed Dementia with Lewy Bodies and Alzheimer's Disease. Neuropsychologia. 75: 548-55. PMID 26184443 DOI: 10.1016/j.neuropsychologia.2015.07.014  0.68
2015 Valera E, Mante M, Anderson S, Rockenstein E, Masliah E. Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease. Journal of Neuroinflammation. 12: 93. PMID 25966683 DOI: 10.1186/s12974-015-0320-x  0.48
2015 Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B. The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice. Plos One. 10: e0126261. PMID 25961568 DOI: 10.1371/journal.pone.0126261  0.92
2015 Dewji NN, Singer SJ, Masliah E, Rockenstein E, Kim M, Harber M, Horwood T. Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's disease. Plos One. 10: e0122451. PMID 25923432 DOI: 10.1371/journal.pone.0122451  0.92
2015 Mandler M, Valera E, Rockenstein E, Mante M, Weninger H, Patrick C, Adame A, Schmidhuber S, Santic R, Schneeberger A, Schmidt W, Mattner F, Masliah E. Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. Molecular Neurodegeneration. 10: 10. PMID 25886309 DOI: 10.1186/s13024-015-0008-9  0.48
2015 Zare-Shahabadi A, Masliah E, Johnson GV, Rezaei N. Autophagy in Alzheimer's disease. Reviews in the Neurosciences. PMID 25870960 DOI: 10.1515/revneuro-2014-0076  0.92
2015 Rockenstein E, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Bisquert A, Trejo-Morales M, Spencer B, Masliah E. A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies. Plos One. 10: e0121570. PMID 25803611 DOI: 10.1371/journal.pone.0121570  0.48
2015 Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/s00401-015-1407-2  0.92
2015 Fields JA, Dumaop W, Crews L, Adame A, Spencer B, Metcalf J, He J, Rockenstein E, Masliah E. Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. Current Hiv Research. 13: 43-54. PMID 25760044  0.48
2015 Zhang D, Lee B, Nutter A, Song P, Dolatabadi N, Parker J, Sanz-Blasco S, Newmeyer T, Ambasudhan R, McKercher SR, Masliah E, Lipton SA. Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid. Journal of Neurochemistry. 133: 898-908. PMID 25692407 DOI: 10.1111/jnc.13074  0.92
2015 Bryant AK, Ellis RJ, Umlauf A, Gouaux B, Soontornniyomkij V, Letendre SL, Achim CL, Masliah E, Grant I, Moore DJ. Antiretroviral therapy reduces neurodegeneration in HIV infection. Aids (London, England). 29: 323-30. PMID 25686681 DOI: 10.1097/QAD.0000000000000553  0.92
2015 Dubal DB, Zhu L, Sanchez PE, Worden K, Broestl L, Johnson E, Ho K, Yu GQ, Kim D, Betourne A, Kuro-O M, Masliah E, Abraham CR, Mucke L. Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2358-71. PMID 25673831 DOI: 10.1523/JNEUROSCI.5791-12.2015  0.92
2015 Mbefo MK, Fares MB, Paleologou K, Oueslati A, Yin G, Tenreiro S, Pinto M, Outeiro T, Zweckstetter M, Masliah E, Lashuel HA. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. The Journal of Biological Chemistry. 290: 9412-27. PMID 25657004 DOI: 10.1074/jbc.M114.610774  0.92
2015 Fields J, Dumaop W, Elueteri S, Campos S, Serger E, Trejo M, Kosberg K, Adame A, Spencer B, Rockenstein E, He JJ, Masliah E. HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1921-38. PMID 25653352 DOI: 10.1523/JNEUROSCI.3207-14.2015  0.48
2015 Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nature Neuroscience. 18: 423-34. PMID 25622143 DOI: 10.1038/nn.3930  0.92
2015 Magen I, Torres ER, Dinh D, Chung A, Masliah E, Chesselet MF. Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease. Journal of Parkinson's Disease. PMID 25588356 DOI: 10.3233/JPD-140503  0.48
2015 Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Overk C, Gonzalez T, Trejo M, Spencer B, Kosberg K, Masliah E. Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions. Acs Chemical Neuroscience. 6: 403-16. PMID 25561023 DOI: 10.1021/cn500332w  0.48
2015 Dhungel N, Eleuteri S, Li LB, Kramer NJ, Chartron JW, Spencer B, Kosberg K, Fields JA, Stafa K, Adame A, Lashuel H, Frydman J, Shen K, Masliah E, Gitler AD. Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein. Neuron. 85: 76-87. PMID 25533483 DOI: 10.1016/j.neuron.2014.11.027  0.48
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Masliah E, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/jamaneurol.2014.2157  0.36
2015 Gaffney PM, Barr B, Rowe JD, Bett C, Drygiannakis I, Giannitti F, Trejo M, Ghassemian M, Martin P, Masliah E, Sigurdson CJ. Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 911-9. PMID 25422367 DOI: 10.1096/fj.14-256081  0.92
2015 Eleuteri S, Di Giovanni S, Rockenstein E, Mante M, Adame A, Trejo M, Wrasidlo W, Wu F, Fraering PC, Masliah E, Lashuel HA. Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease. Neurobiology of Disease. 74: 144-57. PMID 25173807 DOI: 10.1016/j.nbd.2014.08.017  0.48
2015 Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's Disease : Jad. 43: 967-76. PMID 25125464 DOI: 10.3233/JAD-141281  0.92
2015 Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto SI, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Masliah E, et al. Correction to supporting information for "Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss," Proceedings of the National Academy of Sciences of the United States of America. 112: E3751-E3752. DOI: 10.1073/pnas.1511282112  0.36
2014 Poehler AM, Xiang W, Spitzer P, May VE, Meixner H, Rockenstein E, Chutna O, Outeiro TF, Winkler J, Masliah E, Klucken J. Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment. Autophagy. 10: 2171-92. PMID 25484190 DOI: 10.4161/auto.36436  0.92
2014 Koob AO, Shaked GM, Bender A, Bisquertt A, Rockenstein E, Masliah E. Neurogranin binds α-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease. Brain Research. 1591: 102-10. PMID 25446004 DOI: 10.1016/j.brainres.2014.10.013  0.48
2014 Gaffney PM, Imai DM, Clifford DL, Ghassemian M, Sasik R, Chang AN, O'Brien TD, Coppinger J, Trejo M, Masliah E, Munson L, Sigurdson C. Proteomic analysis of highly prevalent amyloid A amyloidosis endemic to endangered island foxes. Plos One. 9: e113765. PMID 25429466 DOI: 10.1371/journal.pone.0113765  0.92
2014 Tank J, da Costa-Goncalves AC, Kamer I, Qadri F, Ubhi K, Rockenstein E, Diedrich A, Masliah E, Gross V, Jordan J. Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes. Physiological Reports. 2. PMID 25428949 DOI: 10.14814/phy2.12209  0.52
2014 Roth DM, Hutt DM, Tong J, Bouchecareilh M, Wang N, Seeley T, Dekkers JF, Beekman JM, Garza D, Drew L, Masliah E, Morimoto RI, Balch WE. Modulation of the maladaptive stress response to manage diseases of protein folding. Plos Biology. 12: e1001998. PMID 25406061 DOI: 10.1371/journal.pbio.1001998  0.92
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, ... ... Masliah E, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/s00401-014-1349-0  0.92
2014 Dubinsky AN, Dastidar SG, Hsu CL, Zahra R, Djakovic SN, Duarte S, Esau CC, Spencer B, Ashe TD, Fischer KM, MacKenna DA, Sopher BL, Masliah E, Gaasterland T, Chau BN, et al. Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy. Cell Metabolism. 20: 626-38. PMID 25295787 DOI: 10.1016/j.cmet.2014.09.001  0.92
2014 Overk CR, Masliah E. Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 13680-1. PMID 25205809 DOI: 10.1073/pnas.1414554111  0.48
2014 Bae EJ, Yang NY, Song M, Lee CS, Lee JS, Jung BC, Lee HJ, Kim S, Masliah E, Sardi SP, Lee SJ. Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein. Nature Communications. 5: 4755. PMID 25156829 DOI: 10.1038/ncomms5755  0.48
2014 Sekiyama K, Waragai M, Akatsu H, Sugama S, Takenouchi T, Takamatsu Y, Fujita M, Sekigawa A, Rockenstein E, Inoue S, La Spada AR, Masliah E, Hashimoto M. Disease-Modifying Effect of Adiponectin in Model of α-Synucleinopathies. Annals of Clinical and Translational Neurology. 1: 479-489. PMID 25126588 DOI: 10.1002/acn3.77  0.52
2014 Wrasidlo W, Crews LA, Tsigelny IF, Stocking E, Kouznetsova VL, Price D, Paulino A, Gonzales T, Overk CR, Patrick C, Rockenstein E, Masliah E. Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. British Journal of Pharmacology. 171: 5757-73. PMID 25117211 DOI: 10.1111/bph.12875  0.48
2014 Desplats P, Dumaop W, Cronin P, Gianella S, Woods S, Letendre S, Smith D, Masliah E, Grant I. Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence. Plos One. 9: e102555. PMID 25054922 DOI: 10.1371/journal.pone.0102555  0.92
2014 Rockenstein E, Ubhi K, Trejo M, Mante M, Patrick C, Adame A, Novak P, Jech M, Doppler E, Moessler H, Masliah E. Cerebrolysinâ„¢ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure. Bmc Neuroscience. 15: 90. PMID 25047000 DOI: 10.1186/1471-2202-15-90  0.48
2014 Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Research & Therapy. 5: 46. PMID 25022790 DOI: 10.1186/scrt440  0.48
2014 Games D, Valera E, Spencer B, Rockenstein E, Mante M, Adame A, Patrick C, Ubhi K, Nuber S, Sacayon P, Zago W, Seubert P, Barbour R, Schenk D, Masliah E. Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9441-54. PMID 25009275 DOI: 10.1523/JNEUROSCI.5314-13.2014  0.48
2014 Spencer B, Emadi S, Desplats P, Eleuteri S, Michael S, Kosberg K, Shen J, Rockenstein E, Patrick C, Adame A, Gonzalez T, Sierks M, Masliah E. ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1753-67. PMID 25008355 DOI: 10.1038/mt.2014.129  0.92
2014 Repunte-Canonigo V, Lefebvre C, George O, Kawamura T, Morales M, Koob GF, Califano A, Masliah E, Sanna PP. Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. Molecular Neurodegeneration. 9: 26. PMID 24980976 DOI: 10.1186/1750-1326-9-26  0.48
2014 Grosso H, Woo JM, Lee KW, Im JY, Masliah E, Junn E, Mouradian MM. Transglutaminase 2 exacerbates α-synuclein toxicity in mice and yeast. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4280-91. PMID 24970392 DOI: 10.1096/fj.14-251413  0.92
2014 Spencer B, Masliah E. Immunotherapy for Alzheimer's disease: past, present and future. Frontiers in Aging Neuroscience. 6: 114. PMID 24959143 DOI: 10.3389/fnagi.2014.00114  0.48
2014 Overk CR, Cartier A, Shaked G, Rockenstein E, Ubhi K, Spencer B, Price DL, Patrick C, Desplats P, Masliah E. Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies. Molecular Neurodegeneration. 9: 18. PMID 24885390 DOI: 10.1186/1750-1326-9-18  0.48
2014 Spencer B, Verma I, Desplats P, Morvinski D, Rockenstein E, Adame A, Masliah E. A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis. The Journal of Biological Chemistry. 289: 17917-31. PMID 24825898 DOI: 10.1074/jbc.M114.557439  0.92
2014 Ambasudhan R, Dolatabadi N, Nutter A, Masliah E, Mckercher SR, Lipton SA. Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells. The Journal of Comparative Neurology. 522: 2845-56. PMID 24756727 DOI: 10.1002/cne.23617  0.92
2014 May VE, Ettle B, Poehler AM, Nuber S, Ubhi K, Rockenstein E, Winner B, Wegner M, Masliah E, Winkler J. α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy. Neurobiology of Aging. 35: 2357-68. PMID 24698767 DOI: 10.1016/j.neurobiolaging.2014.02.028  0.52
2014 Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, ... ... Masliah E, et al. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain : a Journal of Neurology. 137: 1496-513. PMID 24662516 DOI: 10.1093/brain/awu057  0.48
2014 Soontornniyomkij V, Umlauf A, Chung SA, Cochran ML, Soontornniyomkij B, Gouaux B, Toperoff W, Moore DJ, Masliah E, Ellis RJ, Grant I, Achim CL. HIV protease inhibitor exposure predicts cerebral small vessel disease. Aids (London, England). 28: 1297-306. PMID 24637542 DOI: 10.1097/QAD.0000000000000262  0.92
2014 Bae EJ, Lee HJ, Jang YH, Michael S, Masliah E, Min DS, Lee SJ. Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates. Cell Death and Differentiation. 21: 1132-41. PMID 24632948 DOI: 10.1038/cdd.2014.30  0.92
2014 Diepenbroek M, Casadei N, Esmer H, Saido TC, Takano J, Kahle PJ, Nixon RA, Rao MV, Melki R, Pieri L, Helling S, Marcus K, Krueger R, Masliah E, Riess O, et al. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice. Human Molecular Genetics. 23: 3975-89. PMID 24619358 DOI: 10.1093/hmg/ddu112  0.92
2014 Avraham HK, Jiang S, Fu Y, Rockenstein E, Makriyannis A, Wood J, Wang L, Masliah E, Avraham S. Impaired Neurogenesis by HIV-1-Gp120 is Rescued by genetic deletion of Fatty Acid Amide Hydrolase Enzyme. British Journal of Pharmacology. PMID 24571443 DOI: 10.1111/bph.12657  0.48
2014 Mandler M, Valera E, Rockenstein E, Weninger H, Patrick C, Adame A, Santic R, Meindl S, Vigl B, Smrzka O, Schneeberger A, Mattner F, Masliah E. Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials. Acta Neuropathologica. 127: 861-79. PMID 24525765 DOI: 10.1007/s00401-014-1256-4  0.48
2014 Fields J, Dumaop W, Langford TD, Rockenstein E, Masliah E. Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 102-16. PMID 24510686 DOI: 10.1007/s11481-013-9520-2  0.48
2014 Nuber S, Tadros D, Fields J, Overk CR, Ettle B, Kosberg K, Mante M, Rockenstein E, Trejo M, Masliah E. Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD. Acta Neuropathologica. 127: 477-94. PMID 24509835 DOI: 10.1007/s00401-014-1255-5  0.92
2014 Overk CR, Masliah E. Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease. Biochemical Pharmacology. 88: 508-16. PMID 24462903 DOI: 10.1016/j.bcp.2014.01.015  0.48
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Masliah E, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/s00401-013-1239-x  0.92
2014 Mahul-Mellier AL, Fauvet B, Gysbers A, Dikiy I, Oueslati A, Georgeon S, Lamontanara AJ, Bisquertt A, Eliezer D, Masliah E, Halliday G, Hantschel O, Lashuel HA. c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. Human Molecular Genetics. 23: 2858-79. PMID 24412932 DOI: 10.1093/hmg/ddt674  0.92
2014 Kragh CL, Gysbers AM, Rockenstein E, Murphy K, Halliday GM, Masliah E, Jensen PH. Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy. Neurobiology of Disease. 63: 171-83. PMID 24361600 DOI: 10.1016/j.nbd.2013.12.002  0.52
2014 Valera E, Ubhi K, Mante M, Rockenstein E, Masliah E. Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy. Glia. 62: 317-37. PMID 24310907 DOI: 10.1002/glia.22610  0.52
2014 Joshi-Barr S, Bett C, Chiang WC, Trejo M, Goebel HH, Sikorska B, Liberski P, Raeber A, Lin JH, Masliah E, Sigurdson CJ. De novo prion aggregates trigger autophagy in skeletal muscle. Journal of Virology. 88: 2071-82. PMID 24307586 DOI: 10.1128/JVI.02279-13  0.92
2014 Ubhi K, Rockenstein E, Kragh C, Inglis C, Spencer B, Michael S, Mante M, Adame A, Galasko D, Masliah E. Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. The European Journal of Neuroscience. 39: 1026-41. PMID 24304186 DOI: 10.1111/ejn.12444  0.48
2014 Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, et al. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research. 24: 126-9. PMID 24296783 DOI: 10.1038/cr.2013.156  0.92
2014 Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Gonzalez T, Desplats P, Michael SE, Trejo-Morales M, Overk CR, Masliah E. Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation. Journal of Alzheimer's Disease : Jad. 39: 583-600. PMID 24240640 DOI: 10.3233/JAD-131589  0.48
2014 Avraham HK, Jiang S, Fu Y, Rockenstein E, Makriyannis A, Zvonok A, Masliah E, Avraham S. The cannabinoid CBâ‚‚ receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis. British Journal of Pharmacology. 171: 468-79. PMID 24148086 DOI: 10.1111/bph.12478  0.52
2014 Vázquez-Roque RA, Ubhi K, Masliah E, Flores G. Chronic cerebrolysin administration attenuates neuronal abnormalities in the basolateral amygdala induced by neonatal ventral hippocampus lesion in the rat. Synapse (New York, N.Y.). 68: 31-8. PMID 24123373 DOI: 10.1002/syn.21718  0.48
2014 Carbone I, Lazzarotto T, Ianni M, Porcellini E, Forti P, Masliah E, Gabrielli L, Licastro F. Herpes virus in Alzheimer's disease: relation to progression of the disease. Neurobiology of Aging. 35: 122-9. PMID 23916950 DOI: 10.1016/j.neurobiolaging.2013.06.024  0.92
2014 Hamilton JM, Salmon DP, Raman R, Hansen LA, Masliah E, Peavy GM, Galasko D. Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: beyond cognition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 171-8. PMID 23850331 DOI: 10.1016/j.jalz.2013.04.003  0.92
2013 Fields J, Dumaop W, Adame A, Ellis RJ, Letendre S, Grant I, Masliah E. Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1197-209. PMID 24292993 DOI: 10.1007/s11481-013-9511-3  0.48
2013 Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, ... ... Masliah E, et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. Cell. 155: 1351-64. PMID 24290359 DOI: 10.1016/j.cell.2013.11.009  0.92
2013 Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, ... ... Masliah E, et al. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 80: 270-4. PMID 24139032 DOI: 10.1016/j.neuron.2013.09.008  0.92
2013 Duka V, Lee JH, Credle J, Wills J, Oaks A, Smolinsky C, Shah K, Mash DC, Masliah E, Sidhu A. Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases. Plos One. 8: e75025. PMID 24073234 DOI: 10.1371/journal.pone.0075025  0.92
2013 Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH. Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15596-602. PMID 24068826 DOI: 10.1523/JNEUROSCI.5195-12.2013  0.92
2013 DeBoever C, Reid EG, Smith EN, Wang X, Dumaop W, Harismendy O, Carson D, Richman D, Masliah E, Frazer KA. Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. Plos One. 8: e73956. PMID 24023918 DOI: 10.1371/journal.pone.0073956  0.92
2013 Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, Wyss-Coray T. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron. 79: 873-86. PMID 24012002 DOI: 10.1016/j.neuron.2013.06.046  0.92
2013 Sunico CR, Nakamura T, Rockenstein E, Mante M, Adame A, Chan SF, Newmeyer TF, Masliah E, Nakanishi N, Lipton SA. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Molecular Neurodegeneration. 8: 29. PMID 23985028 DOI: 10.1186/1750-1326-8-29  0.48
2013 Masliah E, Dumaop W, Galasko D, Desplats P. Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1030-8. PMID 23907097 DOI: 10.4161/epi.25865  0.92
2013 Fleming SM, Jordan MC, Mulligan CK, Masliah E, Holden JG, Millard RW, Chesselet MF, Roos KP. Impaired baroreflex function in mice overexpressing alpha-synuclein. Frontiers in Neurology. 4: 103. PMID 23888153 DOI: 10.3389/fneur.2013.00103  0.92
2013 Marxreiter F, Ettle B, May VE, Esmer H, Patrick C, Kragh CL, Klucken J, Winner B, Riess O, Winkler J, Masliah E, Nuber S. Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice. Neurobiology of Disease. 59: 38-51. PMID 23867236 DOI: 10.1016/j.nbd.2013.07.004  0.92
2013 Sekigawa A, Sekiyama K, Fujita M, Takamatsu Y, La Spada AR, Masliah E, Hashimoto M. Dual effects of β-synuclein on the pathogenesis of Parkinson disease. Annals of Neurology. 74: 306. PMID 23836414 DOI: 10.1002/ana.23936  0.92
2013 Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Masliah E, et al. Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E2518-27. PMID 23776240 DOI: 10.1073/pnas.1306832110  0.92
2013 Mitsui J, Matsukawa T, Ishiura H, Fukuda Y, Ichikawa Y, Date H, Ahsan B, Nakahara Y, Momose Y, Takahashi Y, Iwata A, Goto J, Yamamoto Y, Komata M, Shirahige K, ... ... Masliah E, et al. Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration New England Journal of Medicine. 369: 233-244. PMID 23758206 DOI: 10.1056/NEJMoa1212115  0.92
2013 Sarafian TA, Ryan CM, Souda P, Masliah E, Kar UK, Vinters HV, Mathern GW, Faull KF, Whitelegge JP, Watson JB. Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein. Plos One. 8: e63557. PMID 23667637 DOI: 10.1371/journal.pone.0063557  0.92
2013 Nizar K, Uhlirova H, Tian P, Saisan PA, Cheng Q, Reznichenko L, Weldy KL, Steed TC, Sridhar VB, MacDonald CL, Cui J, Gratiy SL, Sakadzić S, Boas DA, Beka TI, ... ... Masliah E, et al. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8411-22. PMID 23658179 DOI: 10.1523/JNEUROSCI.3285-12.2013  0.92
2013 Bett C, Kurt TD, Lucero M, Trejo M, Rozemuller AJ, Kong Q, Nilsson KP, Masliah E, Oldstone MB, Sigurdson CJ. Defining the conformational features of anchorless, poorly neuroinvasive prions. Plos Pathogens. 9: e1003280. PMID 23637596 DOI: 10.1371/journal.ppat.1003280  0.92
2013 Shaltiel-Karyo R, Frenkel-Pinter M, Rockenstein E, Patrick C, Levy-Sakin M, Schiller A, Egoz-Matia N, Masliah E, Segal D, Gazit E. A blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD). The Journal of Biological Chemistry. 288: 17579-88. PMID 23637226 DOI: 10.1074/jbc.M112.434787  0.92
2013 Bender A, Desplats P, Spencer B, Rockenstein E, Adame A, Elstner M, Laub C, Mueller S, Koob AO, Mante M, Pham E, Klopstock T, Masliah E. TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease. Plos One. 8: e62277. PMID 23626796 DOI: 10.1371/journal.pone.0062277  0.48
2013 Peavy GM, Salmon DP, Edland SD, Tam S, Hansen LA, Masliah E, Galasko D, Hamilton JM. Neuropsychiatric features of frontal lobe dysfunction in autopsy-confirmed patients with lewy bodies and "pure" Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 509-19. PMID 23567425 DOI: 10.1016/j.jagp.2012.10.022  0.92
2013 Vilchez D, Boyer L, Lutz M, Merkwirth C, Morantte I, Tse C, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell. 12: 518-22. PMID 23551888 DOI: 10.1111/acel.12067  0.92
2013 Desplats P, Dumaop W, Smith D, Adame A, Everall I, Letendre S, Ellis R, Cherner M, Grant I, Masliah E. Molecular and pathologic insights from latent HIV-1 infection in the human brain. Neurology. 80: 1415-23. PMID 23486877 DOI: 10.1212/WNL.0b013e31828c2e9e  0.48
2013 Kim C, Ho DH, Suk JE, You S, Michael S, Kang J, Joong Lee S, Masliah E, Hwang D, Lee HJ, Lee SJ. Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia. Nature Communications. 4: 1562. PMID 23463005 DOI: 10.1038/ncomms2534  0.92
2013 Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, ... ... Masliah E, et al. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. Brain : a Journal of Neurology. 136: 412-32. PMID 23413261 DOI: 10.1093/brain/aws358  0.92
2013 Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, ... ... Masliah E, et al. APOE ε4 increases risk for dementia in pure synucleinopathies. Jama Neurology. 70: 223-8. PMID 23407718 DOI: 10.1001/jamaneurol.2013.600  0.92
2013 Dusaban SS, Purcell NH, Rockenstein E, Masliah E, Cho MK, Smrcka AV, Brown JH. Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 3609-14. PMID 23401561 DOI: 10.1073/pnas.1217355110  0.48
2013 Boassa D, Berlanga ML, Yang MA, Terada M, Hu J, Bushong EA, Hwang M, Masliah E, George JM, Ellisman MH. Mapping the subcellular distribution of α-synuclein in neurons using genetically encoded probes for correlated light and electron microscopy: implications for Parkinson's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2605-15. PMID 23392688 DOI: 10.1523/JNEUROSCI.2898-12.2013  0.92
2013 Fields J, Dumaop W, Rockenstein E, Mante M, Spencer B, Grant I, Ellis R, Letendre S, Patrick C, Adame A, Masliah E. Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer. Journal of Neurovirology. 19: 89-101. PMID 23341224 DOI: 10.1007/s13365-012-0145-7  0.48
2013 Morris M, Hamto P, Adame A, Devidze N, Masliah E, Mucke L. Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice. Neurobiology of Aging. 34: 1523-9. PMID 23332171 DOI: 10.1016/j.neurobiolaging.2012.12.003  0.92
2013 Games D, Seubert P, Rockenstein E, Patrick C, Trejo M, Ubhi K, Ettle B, Ghassemiam M, Barbour R, Schenk D, Nuber S, Masliah E. Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein. The American Journal of Pathology. 182: 940-53. PMID 23313024 DOI: 10.1016/j.ajpath.2012.11.018  0.48
2013 Amschl D, Neddens J, Havas D, Flunkert S, Rabl R, Römer H, Rockenstein E, Masliah E, Windisch M, Hutter-Paier B. Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model. Bmc Neuroscience. 14: 6. PMID 23302418 DOI: 10.1186/1471-2202-14-6  0.52
2013 Lashuel HA, Overk CR, Oueslati A, Masliah E. The many faces of α-synuclein: from structure and toxicity to therapeutic target. Nature Reviews. Neuroscience. 14: 38-48. PMID 23254192 DOI: 10.1038/nrn3406  0.48
2013 Gelman BB, Lisinicchia JG, Morgello S, Masliah E, Commins D, Achim CL, Fox HS, Kolson DL, Grant I, Singer E, Yiannoutsos CT, Sherman S, Gensler G, Moore DJ, Chen T, et al. Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort. Journal of Acquired Immune Deficiency Syndromes (1999). 62: 487-95. PMID 23242157 DOI: 10.1097/QAI.0b013e31827f1bdb  0.92
2013 Huang TY, Michael S, Xu T, Sarkeshik A, Moresco JJ, Yates JR, Masliah E, Bokoch GM, DerMardirossian C. A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation. Molecular Biology of the Cell. 24: 194-209. PMID 23223568 DOI: 10.1091/mbc.E12-07-0565  0.92
2013 Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM. Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation. Neurobiology of Aging. 34: 1315-27. PMID 23182244 DOI: 10.1016/j.neurobiolaging.2012.10.028  0.92
2013 Ubhi K, Rockenstein E, Vazquez-Roque R, Mante M, Inglis C, Patrick C, Adame A, Fahnestock M, Doppler E, Novak P, Moessler H, Masliah E. Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease. Journal of Neuroscience Research. 91: 167-77. PMID 23152192 DOI: 10.1002/jnr.23142  0.48
2013 Sherzai A, Edland SD, Masliah E, Hansen L, Pizzo DP, Sherzai A, Corey-Bloom J. Spongiform change in dementia with Lewy bodies and Alzheimer disease. Alzheimer Disease and Associated Disorders. 27: 157-61. PMID 22546782 DOI: 10.1097/WAD.0b013e318256d507  0.92
2013 Spencer B, Michael S, Shen J, Kosberg K, Rockenstein E, Patrick C, Adame A, Masliah E. Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 31-41. PMID 22508489 DOI: 10.1038/mt.2012.66  0.48
2012 Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH. Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16906-16. PMID 23175842 DOI: 10.1523/JNEUROSCI.2723-12.2012  0.92
2012 Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, et al. Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15565-76. PMID 23115192 DOI: 10.1523/JNEUROSCI.3668-12.2012  0.92
2012 Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, et al. The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. Plos One. 7: e46178. PMID 23049970 DOI: 10.1371/journal.pone.0046178  0.92
2012 Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, ... ... Masliah E, et al. GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology. 79: 1944-50. PMID 23035075 DOI: 10.1212/WNL.0b013e3182735e9a  0.92
2012 Harris JA, Koyama A, Maeda S, Ho K, Devidze N, Dubal DB, Yu GQ, Masliah E, Mucke L. Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits. Plos One. 7: e45881. PMID 23029293 DOI: 10.1371/journal.pone.0045881  0.92
2012 Soontornniyomkij V, Moore DJ, Gouaux B, Soontornniyomkij B, Tatro ET, Umlauf A, Masliah E, Levine AJ, Singer EJ, Vinters HV, Gelman BB, Morgello S, Cherner M, Grant I, Achim CL. Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers. Aids (London, England). 26: 2327-35. PMID 23018443 DOI: 10.1097/QAD.0b013e32835a117c  0.92
2012 Desplats P, Patel P, Kosberg K, Mante M, Patrick C, Rockenstein E, Fujita M, Hashimoto M, Masliah E. Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease. Molecular Neurodegeneration. 7: 49. PMID 23017109 DOI: 10.1186/1750-1326-7-49  0.48
2012 Bae EJ, Lee HJ, Rockenstein E, Ho DH, Park EB, Yang NY, Desplats P, Masliah E, Lee SJ. Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13454-69. PMID 23015436 DOI: 10.1523/JNEUROSCI.1292-12.2012  0.92
2012 Sekigawa A, Fujita M, Sekiyama K, Takamatsu Y, Hatano T, Rockenstein E, La Spada AR, Masliah E, Hashimoto M. Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein. Molecular Brain. 5: 34. PMID 23013868 DOI: 10.1186/1756-6606-5-34  0.48
2012 Britschgi M, Takeda-Uchimura Y, Rockenstein E, Johns H, Masliah E, Wyss-Coray T. Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. Journal of Neuroinflammation. 9: 220. PMID 22989354 DOI: 10.1186/1742-2094-9-220  0.48
2012 Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 489: 304-8. PMID 22972301 DOI: 10.1038/nature11468  0.92
2012 Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, Masliah E, Xu H. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11390-5. PMID 22895721 DOI: 10.1523/JNEUROSCI.0757-12.2012  0.92
2012 Kwak YD, Wang B, Li JJ, Wang R, Deng Q, Diao S, Chen Y, Xu R, Masliah E, Xu H, Sung JJ, Liao FF. Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10971-81. PMID 22875931 DOI: 10.1523/JNEUROSCI.1836-12.2012  0.4
2012 Siggs OM, Cruite JT, Du X, Rutschmann S, Masliah E, Beutler B, Oldstone MB. Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 13733-8. PMID 22869751 DOI: 10.1073/pnas.1211499109  0.92
2012 Hafez DM, Huang JY, Richardson JC, Masliah E, Peterson DA, Marr RA. F-spondin gene transfer improves memory performance and reduces amyloid-β levels in mice. Neuroscience. 223: 465-72. PMID 22863679 DOI: 10.1016/j.neuroscience.2012.07.038  0.92
2012 Desplats P, Spencer B, Crews L, Pathel P, Morvinski-Friedmann D, Kosberg K, Roberts S, Patrick C, Winner B, Winkler J, Masliah E. α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. The Journal of Biological Chemistry. 287: 31691-702. PMID 22833673 DOI: 10.1074/jbc.M112.354522  0.92
2012 Reznichenko L, Cheng Q, Nizar K, Gratiy SL, Saisan PA, Rockenstein EM, González T, Patrick C, Spencer B, Desplats P, Dale AM, Devor A, Masliah E. In vivo alterations in calcium buffering capacity in transgenic mouse model of synucleinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9992-8. PMID 22815513 DOI: 10.1523/JNEUROSCI.1270-12.2012  0.92
2012 Tsunemi T, Ashe TD, Morrison BE, Soriano KR, Au J, Roque RA, Lazarowski ER, Damian VA, Masliah E, La Spada AR. PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function. Science Translational Medicine. 4: 142ra97. PMID 22786682 DOI: 10.1126/scitranslmed.3003799  0.92
2012 Watson MB, Richter F, Lee SK, Gabby L, Wu J, Masliah E, Effros RB, Chesselet MF. Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein. Experimental Neurology. 237: 318-34. PMID 22750327 DOI: 10.1016/j.expneurol.2012.06.025  0.92
2012 Pillai JA, Hansen LA, Masliah E, Goldstein JL, Edland SD, Corey-Bloom J. Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1099-103. PMID 22674458 DOI: 10.1002/mds.25026  0.92
2012 Klucken J, Poehler AM, Ebrahimi-Fakhari D, Schneider J, Nuber S, Rockenstein E, Schlötzer-Schrehardt U, Hyman BT, McLean PJ, Masliah E, Winkler J. Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway. Autophagy. 8: 754-66. PMID 22647715 DOI: 10.4161/auto.19371  0.92
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Masliah E, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/hmg/dds161  0.48
2012 Kofler J, Lopresti B, Janssen C, Trichel AM, Masliah E, Finn OJ, Salter RD, Murdoch GH, Mathis CA, Wiley CA. Preventive immunization of aged and juvenile non-human primates to β-amyloid. Journal of Neuroinflammation. 9: 84. PMID 22554253 DOI: 10.1186/1742-2094-9-84  0.48
2012 Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell. 149: 708-21. PMID 22541439 DOI: 10.1016/j.cell.2012.02.046  0.92
2012 Cartier AE, Ubhi K, Spencer B, Vazquez-Roque RA, Kosberg KA, Fourgeaud L, Kanayson P, Patrick C, Rockenstein E, Patrick GN, Masliah E. Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy. Plos One. 7: e34713. PMID 22514658 DOI: 10.1371/journal.pone.0034713  0.48
2012 Tang B, Becanovic K, Desplats PA, Spencer B, Hill AM, Connolly C, Masliah E, Leavitt BR, Thomas EA. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease. Human Molecular Genetics. 21: 3097-111. PMID 22492998 DOI: 10.1093/hmg/dds132  0.92
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, ... ... Masliah E, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/NEN.0b013e31825018f7  0.92
2012 Masliah E, Rockenstein E, Inglis C, Adame A, Bett C, Lucero M, Sigurdson CJ. Prion infection promotes extensive accumulation of α-synuclein in aged human α-synuclein transgenic mice. Prion. 6: 184-90. PMID 22460692 DOI: 10.4161/pri.19806  0.48
2012 Soontornniyomkij V, Soontornniyomkij B, Moore DJ, Gouaux B, Masliah E, Tung S, Vinters HV, Grant I, Achim CL. Antioxidant sestrin-2 redistribution to neuronal soma in human immunodeficiency virus-associated neurocognitive disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 579-90. PMID 22450766 DOI: 10.1007/s11481-012-9357-0  0.92
2012 Koob AO, Bruns L, Prassler C, Masliah E, Klopstock T, Bender A. Protein analysis through Western blot of cells excised individually from human brain and muscle tissue. Analytical Biochemistry. 425: 120-4. PMID 22402104 DOI: 10.1016/j.ab.2012.02.034  0.48
2012 Sancenon V, Lee SA, Patrick C, Griffith J, Paulino A, Outeiro TF, Reggiori F, Masliah E, Muchowski PJ. Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context. Human Molecular Genetics. 21: 2432-49. PMID 22357655 DOI: 10.1093/hmg/dds058  0.92
2012 Magen I, Fleming SM, Zhu C, Garcia EC, Cardiff KM, Dinh D, De La Rosa K, Sanchez M, Torres ER, Masliah E, Jentsch JD, Chesselet MF. Cognitive deficits in a mouse model of pre-manifest Parkinson's disease. The European Journal of Neuroscience. 35: 870-82. PMID 22356593 DOI: 10.1111/j.1460-9568.2012.08012.x  0.92
2012 Bett C, Joshi-Barr S, Lucero M, Trejo M, Liberski P, Kelly JW, Masliah E, Sigurdson CJ. Biochemical properties of highly neuroinvasive prion strains. Plos Pathogens. 8: e1002522. PMID 22319450 DOI: 10.1371/journal.ppat.1002522  0.92
2012 Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, ... Masliah E, et al. α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. The Journal of Biological Chemistry. 287: 15345-64. PMID 22315227 DOI: 10.1074/jbc.M111.318949  0.92
2012 Rockenstein E, Ubhi K, Inglis C, Mante M, Patrick C, Adame A, Masliah E. Neuronal to oligodendroglial α-synuclein redistribution in a double transgenic model of multiple system atrophy. Neuroreport. 23: 259-64. PMID 22314685 DOI: 10.1097/WNR.0b013e3283509842  0.52
2012 Ubhi K, Inglis C, Mante M, Patrick C, Adame A, Spencer B, Rockenstein E, May V, Winkler J, Masliah E. Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy. Experimental Neurology. 234: 405-16. PMID 22281106 DOI: 10.1016/j.expneurol.2012.01.008  0.52
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/j.jalz.2011.10.007  0.92
2012 Tsigelny IF, Sharikov Y, Wrasidlo W, Gonzalez T, Desplats PA, Crews L, Spencer B, Masliah E. Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation. The Febs Journal. 279: 1000-13. PMID 22251432 DOI: 10.1111/j.1742-4658.2012.08489.x  0.48
2012 Soontornniyomkij V, Everall IP, Moore DJ, Gouaux B, Tatro ET, Gospodarev V, Masliah E, Yin NS, Vinters HV, Achim CL. Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders. Journal of Neurovirology. 18: 313-22. PMID 22234543 DOI: 10.1007/s13365-011-0076-8  0.92
2012 Kwan W, Magnusson A, Chou A, Adame A, Carson MJ, Kohsaka S, Masliah E, Möller T, Ransohoff R, Tabrizi SJ, Björkqvist M, Muchowski PJ. Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 133-42. PMID 22219276 DOI: 10.1523/JNEUROSCI.4846-11.2012  0.92
2012 Kohl Z, Winner B, Ubhi K, Rockenstein E, Mante M, Münch M, Barlow C, Carter T, Masliah E, Winkler J. Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model. The European Journal of Neuroscience. 35: 10-9. PMID 22211740 DOI: 10.1111/j.1460-9568.2011.07933.x  0.92
2012 Masliah E, Hansen LA. Alzheimer disease: AD pathology--emerging subtypes or age-of-onset spectrum? Nature Reviews. Neurology. 8: 11-2. PMID 22143361 DOI: 10.1038/nrneurol.2011.205  0.68
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/s00401-011-0910-3  0.92
2012 Mandler M, Rockenstein E, Ubhi K, Hansen L, Adame A, Michael S, Galasko D, Santic R, Mattner F, Masliah E. Detection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibody. Journal of Alzheimer's Disease : Jad. 28: 783-94. PMID 22064070 DOI: 10.3233/JAD-2011-111208  0.48
2012 Hamilton JM, Landy KM, Salmon DP, Hansen LA, Masliah E, Galasko D. Early visuospatial deficits predict the occurrence of visual hallucinations in autopsy-confirmed dementia with Lewy bodies. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 20: 773-81. PMID 21997600 DOI: 10.1097/JGP.0b013e31823033bc  0.92
2012 Vázquez-Roque RA, Ramos B, Tecuatl C, Juárez I, Adame A, de la Cruz F, Zamudio S, Mena R, Rockenstein E, Masliah E, Flores G. Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia. Journal of Neuroscience Research. 90: 288-306. PMID 21932359 DOI: 10.1002/jnr.22753  0.92
2012 Ubhi K, Crews L, Masliah E. Alpha-Synuclein and Neurodegeneration Primer On the Autonomic Nervous System. 303-305. DOI: 10.1016/B978-0-12-386525-0.00063-9  0.48
2011 Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT. Neuropathological alterations in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 1: a006189. PMID 22229116 DOI: 10.1101/cshperspect.a006189  0.92
2011 Morris M, Koyama A, Masliah E, Mucke L. Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease. Plos One. 6: e29257. PMID 22206005 DOI: 10.1371/journal.pone.0029257  0.92
2011 Elstner M, Müller SK, Leidolt L, Laub C, Krieg L, Schlaudraff F, Liss B, Morris C, Turnbull DM, Masliah E, Prokisch H, Klopstock T, Bender A. Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions. Molecular Brain. 4: 43. PMID 22188897 DOI: 10.1186/1756-6606-4-43  0.48
2011 Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF, Schiestl RH. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Molecular Neurodegeneration. 6: 83. PMID 22165993 DOI: 10.1186/1750-1326-6-83  0.48
2011 Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Masliah E, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/nchembio.694  0.92
2011 Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14508-20. PMID 21994367 DOI: 10.1523/JNEUROSCI.1560-11.2011  0.92
2011 Crews L, Ruf R, Patrick C, Dumaop W, Trejo-Morales M, Achim CL, Rockenstein E, Masliah E. Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Molecular Neurodegeneration. 6: 67. PMID 21943307 DOI: 10.1186/1750-1326-6-67  0.48
2011 Cho EG, Zaremba JD, McKercher SR, Talantova M, Tu S, Masliah E, Chan SF, Nakanishi N, Terskikh A, Lipton SA. MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model. Plos One. 6: e24027. PMID 21901155 DOI: 10.1371/journal.pone.0024027  0.92
2011 Rockenstein E, Ubhi K, Doppler E, Novak P, Moessler H, Li B, Blanchard J, Grundke-Iqbal I, Iqbal K, Mante M, Adame A, Crews L, Masliah E. Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice. Journal of Alzheimer's Disease : Jad. 27: 743-52. PMID 21860085 DOI: 10.3233/JAD-2011-110914  0.48
2011 Singh KK, Nathamu S, Adame A, Alire TU, Dumaop W, Gouaux B, Moore DJ, Masliah E. Expression of mannose binding lectin in HIV-1-infected brain: implications for HIV-related neuronal damage and neuroAIDS. Neurobehavioral Hiv Medicine. 3: 41-52. PMID 21852898 DOI: 10.2147/NBHIV.S19969  0.92
2011 Kaul T, Credle J, Haggerty T, Oaks AW, Masliah E, Sidhu A. Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease. Bmc Neuroscience. 12: 79. PMID 21812967 DOI: 10.1186/1471-2202-12-79  0.48
2011 Rockenstein E, Ubhi K, Pham E, Michael S, Doppler E, Novak P, Inglis C, Mante M, Adame A, Alvarez XA, Moessler H, Masliah E. Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease. Journal of Neuroscience Research. 89: 1812-21. PMID 21793038 DOI: 10.1002/jnr.22712  0.52
2011 Ho GJ, Liang W, Waragai M, Sekiyama K, Masliah E, Hashimoto M. Bridging molecular genetics and biomarkers in lewy body and related disorders. International Journal of Alzheimer's Disease. 2011: 842475. PMID 21760990 DOI: 10.4061/2011/842475  0.36
2011 Paulino AD, Ubhi K, Rockenstein E, Adame A, Crews L, Letendre S, Ellis R, Everall IP, Grant I, Masliah E. Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling. Journal of Neurovirology. 17: 327-40. PMID 21660601 DOI: 10.1007/s13365-011-0039-0  0.48
2011 Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, ... ... Masliah E, et al. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell. 145: 863-74. PMID 21640374 DOI: 10.1016/j.cell.2011.05.020  0.92
2011 Lee SJ, Lim HS, Masliah E, Lee HJ. Protein aggregate spreading in neurodegenerative diseases: problems and perspectives. Neuroscience Research. 70: 339-48. PMID 21624403 DOI: 10.1016/j.neures.2011.05.008  0.92
2011 Meng F, Yao D, Shi Y, Kabakoff J, Wu W, Reicher J, Ma Y, Moosmann B, Masliah E, Lipton SA, Gu Z. Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation. Molecular Neurodegeneration. 6: 34. PMID 21595948 DOI: 10.1186/1750-1326-6-34  0.48
2011 Lee KW, Chen W, Junn E, Im JY, Grosso H, Sonsalla PK, Feng X, Ray N, Fernandez JR, Chao Y, Masliah E, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6963-71. PMID 21562258 DOI: 10.1523/JNEUROSCI.6513-10.2011  0.92
2011 Masliah E, Rockenstein E, Mante M, Crews L, Spencer B, Adame A, Patrick C, Trejo M, Ubhi K, Rohn TT, Mueller-Steiner S, Seubert P, Barbour R, McConlogue L, Buttini M, et al. Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease. Plos One. 6: e19338. PMID 21559417 DOI: 10.1371/journal.pone.0019338  0.48
2011 Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, et al. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. The Journal of Biological Chemistry. 286: 20710-26. PMID 21489994 DOI: 10.1074/jbc.M110.213538  0.92
2011 Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein. Journal of Neuroscience Research. 89: 1091-102. PMID 21488084 DOI: 10.1002/jnr.22611  0.92
2011 Ratai EM, Pilkenton S, He J, Fell R, Bombardier JP, Joo CG, Lentz MR, Kim WK, Burdo TH, Autissier P, Annamalai L, Curran E, O'Neil SP, Westmoreland SV, Williams KC, ... Masliah E, et al. CD8+ lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain. Journal of Medical Primatology. 40: 300-9. PMID 21463330 DOI: 10.1111/j.1600-0684.2011.00475.x  0.92
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Masliah E, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/ng.801  0.36
2011 Haggerty T, Credle J, Rodriguez O, Wills J, Oaks AW, Masliah E, Sidhu A. Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson's disease. The European Journal of Neuroscience. 33: 1598-610. PMID 21453448 DOI: 10.1111/j.1460-9568.2011.07660.x  0.92
2011 Patrick C, Crews L, Desplats P, Dumaop W, Rockenstein E, Achim CL, Everall IP, Masliah E. Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine. The American Journal of Pathology. 178: 1646-61. PMID 21435449 DOI: 10.1016/j.ajpath.2010.12.033  0.48
2011 Havas D, Hutter-Paier B, Ubhi K, Rockenstein E, Crailsheim K, Masliah E, Windisch M. A longitudinal study of behavioral deficits in an AβPP transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 231-43. PMID 21403389 DOI: 10.3233/JAD-2011-101866  0.52
2011 Ratai EM, Annamalai L, Burdo T, Joo CG, Bombardier JP, Fell R, Hakimelahi R, He J, Lentz MR, Campbell J, Curran E, Halpern EF, Masliah E, Westmoreland SV, Williams KC, et al. Brain creatine elevation and N-Acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of neuroAIDS. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 66: 625-34. PMID 21381104 DOI: 10.1002/mrm.22821  0.92
2011 Crews L, Patrick C, Adame A, Rockenstein E, Masliah E. Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease. Cell Death & Disease. 2: e120. PMID 21368891 DOI: 10.1038/cddis.2011.2  0.48
2011 Song W, Chen J, Petrilli A, Liot G, Klinglmayr E, Zhou Y, Poquiz P, Tjong J, Pouladi MA, Hayden MR, Masliah E, Ellisman M, Rouiller I, Schwarzenbacher R, Bossy B, et al. Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nature Medicine. 17: 377-82. PMID 21336284 DOI: 10.1038/nm.2313  0.92
2011 Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, ... ... Masliah E, et al. In vivo demonstration that alpha-synuclein oligomers are toxic. Proceedings of the National Academy of Sciences of the United States of America. 108: 4194-9. PMID 21325059 DOI: 10.1073/pnas.1100976108  0.92
2011 Spencer B, Marr RA, Gindi R, Potkar R, Michael S, Adame A, Rockenstein E, Verma IM, Masliah E. Peripheral delivery of a CNS targeted, metalo-protease reduces aβ toxicity in a mouse model of Alzheimer's disease. Plos One. 6: e16575. PMID 21304989 DOI: 10.1371/journal.pone.0016575  0.48
2011 Desplats P, Spencer B, Coffee E, Patel P, Michael S, Patrick C, Adame A, Rockenstein E, Masliah E. Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases. The Journal of Biological Chemistry. 286: 9031-7. PMID 21296890 DOI: 10.1074/jbc.C110.212589  0.52
2011 Hafez D, Huang JY, Huynh AM, Valtierra S, Rockenstein E, Bruno AM, Lu B, DesGroseillers L, Masliah E, Marr RA. Neprilysin-2 is an important β-amyloid degrading enzyme. The American Journal of Pathology. 178: 306-12. PMID 21224067 DOI: 10.1016/j.ajpath.2010.11.012  0.92
2011 Rohn TT, Wirawan E, Brown RJ, Harris JR, Masliah E, Vandenabeele P. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiology of Disease. 43: 68-78. PMID 21081164 DOI: 10.1016/j.nbd.2010.11.003  0.44
2011 Merrill DA, Masliah E, Roberts JA, McKay H, Kordower JH, Mufson EJ, Tuszynski MH. Association of early experience with neurodegeneration in aged primates. Neurobiology of Aging. 32: 151-6. PMID 19321231 DOI: 10.1016/j.neurobiolaging.2009.01.014  0.92
2010 Price DL, Rockenstein E, Ubhi K, Phung V, MacLean-Lewis N, Askay D, Cartier A, Spencer B, Patrick C, Desplats P, Ellisman MH, Masliah E. Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity. Plos One. 5: e14020. PMID 21103359 DOI: 10.1371/journal.pone.0014020  0.48
2010 Kwak YD, Ma T, Diao S, Zhang X, Chen Y, Hsu J, Lipton SA, Masliah E, Xu H, Liao FF. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. Molecular Neurodegeneration. 5: 49. PMID 21067594 DOI: 10.1186/1750-1326-5-49  0.48
2010 Fujita M, Sugama S, Sekiyama K, Sekigawa A, Tsukui T, Nakai M, Waragai M, Takenouchi T, Takamatsu Y, Wei J, Rockenstein E, Laspada AR, Masliah E, Inoue S, Hashimoto M. A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain. Nature Communications. 1: 110. PMID 21045828 DOI: 10.1038/ncomms1101  0.52
2010 Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, Kim D, Hamto P, Lo I, Yu GQ, Palop JJ, Masliah E, Mucke L. Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron. 68: 428-41. PMID 21040845 DOI: 10.1016/j.neuron.2010.10.020  0.92
2010 Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron. 67: 953-66. PMID 20869593 DOI: 10.1016/j.neuron.2010.08.044  0.92
2010 Ubhi K, Peng K, Lessig S, Estrella J, Adame A, Galasko D, Salmon DP, Hansen LA, Kawas CH, Masliah E. Neuropathology of dementia with Lewy bodies in advanced age: a comparison with Alzheimer disease. Neuroscience Letters. 485: 222-7. PMID 20849919 DOI: 10.1016/j.neulet.2010.09.016  0.48
2010 Crews L, Adame A, Patrick C, Delaney A, Pham E, Rockenstein E, Hansen L, Masliah E. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12252-62. PMID 20844121 DOI: 10.1523/JNEUROSCI.1305-10.2010  0.48
2010 Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, et al. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 16970-5. PMID 20837543 DOI: 10.1073/pnas.1011751107  0.92
2010 Kang YJ, Digicaylioglu M, Russo R, Kaul M, Achim CL, Fletcher L, Masliah E, Lipton SA. Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders. Annals of Neurology. 68: 342-52. PMID 20818790 DOI: 10.1002/ana.22070  0.92
2010 Clark J, Clore EL, Zheng K, Adame A, Masliah E, Simon DK. Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. Plos One. 5: e12333. PMID 20808797 DOI: 10.1371/journal.pone.0012333  0.92
2010 Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10541-50. PMID 20685997 DOI: 10.1523/JNEUROSCI.0146-10.2010  0.92
2010 Buttini M, Masliah E, Yu GQ, Palop JJ, Chang S, Bernardo A, Lin C, Wyss-Coray T, Huang Y, Mucke L. Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. The American Journal of Pathology. 177: 563-9. PMID 20595630 DOI: 10.2353/ajpath.2010.090973  0.92
2010 Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E. Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins. The Febs Journal. 277: 3051-67. PMID 20573181 DOI: 10.1111/j.1742-4658.2010.07719.x  0.48
2010 Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T. Regulation of amyloid precursor protein processing by the Beclin 1 complex. Plos One. 5: e11102. PMID 20559548 DOI: 10.1371/journal.pone.0011102  0.92
2010 Scott DA, Tabarean I, Tang Y, Cartier A, Masliah E, Roy S. A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8083-95. PMID 20554859 DOI: 10.1523/JNEUROSCI.1091-10.2010  0.92
2010 Lessig S, Ubhi K, Galasko D, Adame A, Pham E, Remidios K, Chang M, Hansen LA, Masliah E. Reduced hypocretin (orexin) levels in dementia with Lewy bodies. Neuroreport. 21: 756-60. PMID 20531237 DOI: 10.1097/WNR.0b013e32833bfb7c  0.92
2010 Unni VK, Weissman TA, Rockenstein E, Masliah E, McLean PJ, Hyman BT. In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility. Plos One. 5: e10589. PMID 20485674 DOI: 10.1371/journal.pone.0010589  0.92
2010 Ratai EM, Bombardier JP, Joo CG, Annamalai L, Burdo TH, Campbell J, Fell R, Hakimelahi R, He J, Autissier P, Lentz MR, Halpern EF, Masliah E, Williams KC, Westmoreland SV, et al. Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS. Plos One. 5: e10523. PMID 20479889 DOI: 10.1371/journal.pone.0010523  0.92
2010 Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Whitney K, Masliah E. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6236-46. PMID 20445049 DOI: 10.1523/JNEUROSCI.0567-10.2010  0.48
2010 Tatro ET, Scott ER, Nguyen TB, Salaria S, Banerjee S, Moore DJ, Masliah E, Achim CL, Everall IP. Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-infected brain: novel analysis of retrospective cases. Plos One. 5: e10337. PMID 20436668 DOI: 10.1371/journal.pone.0010337  0.92
2010 Masliah E, Xie F, Dayan S, Rockenstein E, Mante M, Adame A, Patrick CM, Chan AF, Zheng B. Genetic deletion of Nogo/Rtn4 ameliorates behavioral and neuropathological outcomes in amyloid precursor protein transgenic mice. Neuroscience. 169: 488-94. PMID 20433905 DOI: 10.1016/j.neuroscience.2010.04.045  0.92
2010 Crews L, Masliah E. Molecular mechanisms of neurodegeneration in Alzheimer's disease. Human Molecular Genetics. 19: R12-20. PMID 20413653 DOI: 10.1093/hmg/ddq160  0.48
2010 Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a Journal of Neurology. 133: 1312-27. PMID 20360050 DOI: 10.1093/brain/awq056  0.92
2010 Alcantara-Gonzalez F, Juarez I, Solis O, Martinez-Tellez I, Camacho-Abrego I, Masliah E, Mena R, Flores G. Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus, and nucleus accumbens in old rats after chronic donepezil administration. Synapse (New York, N.Y.). 64: 786-93. PMID 20336627 DOI: 10.1002/syn.20787  0.92
2010 Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Masliah E. Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy. Neuroreport. 21: 457-62. PMID 20224454 DOI: 10.1097/WNR.0b013e328338ba6b  0.52
2010 Paleologou KE, Oueslati A, Shakked G, Rospigliosi CC, Kim HY, Lamberto GR, Fernandez CO, Schmid A, Chegini F, Gai WP, Chiappe D, Moniatte M, Schneider BL, Aebischer P, Eliezer D, ... ... Masliah E, et al. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3184-98. PMID 20203178 DOI: 10.1523/JNEUROSCI.5922-09.2010  0.92
2010 Crews L, Spencer B, Desplats P, Patrick C, Paulino A, Rockenstein E, Hansen L, Adame A, Galasko D, Masliah E. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy. Plos One. 5: e9313. PMID 20174468 DOI: 10.1371/journal.pone.0009313  0.48
2010 Crews L, Rockenstein E, Masliah E. APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis. Brain Structure & Function. 214: 111-26. PMID 20091183 DOI: 10.1007/s00429-009-0232-6  0.48
2010 Harris JA, Devidze N, Halabisky B, Lo I, Thwin MT, Yu GQ, Bredesen DE, Masliah E, Mucke L. Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 372-81. PMID 20053918 DOI: 10.1523/JNEUROSCI.5341-09.2010  0.92
2010 Wu N, Joshi PR, Cepeda C, Masliah E, Levine MS. Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway. Journal of Neuroscience Research. 88: 1764-76. PMID 20029978 DOI: 10.1002/jnr.22327  0.92
2010 Koob AO, Ubhi K, Paulsson JF, Kelly J, Rockenstein E, Mante M, Adame A, Masliah E. Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. Experimental Neurology. 221: 267-74. PMID 19944097 DOI: 10.1016/j.expneurol.2009.11.015  0.48
2010 Koob AO, Paulino AD, Masliah E. GFAP reactivity, apolipoprotein E redistribution and cholesterol reduction in human astrocytes treated with alpha-synuclein. Neuroscience Letters. 469: 11-4. PMID 19932737 DOI: 10.1016/j.neulet.2009.11.034  0.48
2010 Jolivalt CG, Hurford R, Lee CA, Dumaop W, Rockenstein E, Masliah E. Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice. Experimental Neurology. 223: 422-31. PMID 19931251 DOI: 10.1016/j.expneurol.2009.11.005  0.52
2010 Mbefo MK, Paleologou KE, Boucharaba A, Oueslati A, Schell H, Fournier M, Olschewski D, Yin G, Zweckstetter M, Masliah E, Kahle PJ, Hirling H, Lashuel HA. Phosphorylation of synucleins by members of the Polo-like kinase family. The Journal of Biological Chemistry. 285: 2807-22. PMID 19889641 DOI: 10.1074/jbc.M109.081950  0.92
2010 Baughn MR, Vaux K, Masliah E. Placenta accreta in a separate uterine horn. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 13: 63-5. PMID 19642813 DOI: 10.2350/09-03-0627-CR.1  0.92
2009 Everall I, Vaida F, Khanlou N, Lazzaretto D, Achim C, Letendre S, Moore D, Ellis R, Cherner M, Gelman B, Morgello S, Singer E, Grant I, Masliah E. Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy. Journal of Neurovirology. 15: 360-70. PMID 20175693 DOI: 10.3109/13550280903131915  0.92
2009 Cohen E, Paulsson JF, Blinder P, Burstyn-Cohen T, Du D, Estepa G, Adame A, Pham HM, Holzenberger M, Kelly JW, Masliah E, Dillin A. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice. Cell. 139: 1157-69. PMID 20005808 DOI: 10.1016/j.cell.2009.11.014  0.92
2009 Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, Adame A, Wyss-Coray T, Masliah E. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13578-88. PMID 19864570 DOI: 10.1523/JNEUROSCI.4390-09.2009  0.48
2009 Nguyen TB, Lucero GR, Chana G, Hult BJ, Tatro ET, Masliah E, Grant I, Achim CL, Everall IP. Glycogen synthase kinase-3beta (GSK-3beta) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons. Journal of Neurovirology. 15: 434-8. PMID 19688630 DOI: 10.1080/13550280903168131  0.92
2009 Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life. Neurobiology of Disease. 36: 293-302. PMID 19660551 DOI: 10.1016/j.nbd.2009.07.021  0.92
2009 Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee SJ. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proceedings of the National Academy of Sciences of the United States of America. 106: 13010-5. PMID 19651612 DOI: 10.1073/pnas.0903691106  0.48
2009 Wacker JL, Huang SY, Steele AD, Aron R, Lotz GP, Nguyen Q, Giorgini F, Roberson ED, Lindquist S, Masliah E, Muchowski PJ. Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9104-14. PMID 19605647 DOI: 10.1523/JNEUROSCI.2250-09.2009  0.92
2009 Dziewczapolski G, Glogowski CM, Masliah E, Heinemann SF. Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8805-15. PMID 19587288 DOI: 10.1523/JNEUROSCI.6159-08.2009  0.92
2009 Crews L, Tsigelny I, Hashimoto M, Masliah E. Role of synucleins in Alzheimer's disease. Neurotoxicity Research. 16: 306-17. PMID 19551456 DOI: 10.1007/s12640-009-9073-6  0.48
2009 Cartier AE, Djakovic SN, Salehi A, Wilson SM, Masliah E, Patrick GN. Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7857-68. PMID 19535597 DOI: 10.1523/JNEUROSCI.1817-09.2009  0.92
2009 Bengoechea TG, Chen Z, O'Leary DA, O'Leary D, Masliah E, Lee KF. p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 106: 7870-5. PMID 19416837 DOI: 10.1073/pnas.0901533106  0.92
2009 Ubhi K, Lee PH, Adame A, Inglis C, Mante M, Rockenstein E, Stefanova N, Wenning GK, Masliah E. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. Journal of Neuroscience Research. 87: 2728-39. PMID 19405128 DOI: 10.1002/jnr.22089  0.52
2009 Crews L, Patrick C, Achim CL, Everall IP, Masliah E. Molecular pathology of neuro-AIDS (CNS-HIV). International Journal of Molecular Sciences. 10: 1045-63. PMID 19399237 DOI: 10.3390/ijms10031045  0.48
2009 Shaked GM, Chauv S, Ubhi K, Hansen LA, Masliah E. Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease. The Febs Journal. 276: 2736-51. PMID 19368557 DOI: 10.1111/j.1742-4658.2009.06997.x  0.68
2009 Watson JB, Hatami A, David H, Masliah E, Roberts K, Evans CE, Levine MS. Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein. Neuroscience. 159: 501-13. PMID 19361478 DOI: 10.1016/j.neuroscience.2009.01.021  0.92
2009 Wei J, Fujita M, Nakai M, Waragai M, Sekigawa A, Sugama S, Takenouchi T, Masliah E, Hashimoto M. Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies. The American Journal of Pathology. 174: 1891-909. PMID 19349362 DOI: 10.2353/ajpath.2009.080680  0.36
2009 Belichenko PV, Wright EE, Belichenko NP, Masliah E, Li HH, Mobley WC, Francke U. Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks. The Journal of Comparative Neurology. 514: 240-58. PMID 19296534 DOI: 10.1002/cne.22009  0.92
2009 Achim CL, Adame A, Dumaop W, Everall IP, Masliah E. Increased accumulation of intraneuronal amyloid beta in HIV-infected patients. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 190-9. PMID 19288297 DOI: 10.1007/s11481-009-9152-8  0.48
2009 Ubhi K, Rockenstein E, Doppler E, Mante M, Adame A, Patrick C, Trejo M, Crews L, Paulino A, Moessler H, Masliah E. Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin. Acta Neuropathologica. 117: 699-712. PMID 19252918 DOI: 10.1007/s00401-009-0505-4  0.48
2009 Tatro ET, Everall IP, Masliah E, Hult BJ, Lucero G, Chana G, Soontornniyomkij V, Achim CL. Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 218-26. PMID 19199039 DOI: 10.1007/s11481-009-9146-6  0.92
2009 Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nature Medicine. 15: 331-7. PMID 19198615 DOI: 10.1038/nm.1912  0.92
2009 Chu J, Hong NA, Masuda CA, Jenkins BV, Nelms KA, Goodnow CC, Glynne RJ, Wu H, Masliah E, Joazeiro CA, Kay SA. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 106: 2097-103. PMID 19196968 DOI: 10.1073/pnas.0812819106  0.92
2009 Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1115-25. PMID 19176820 DOI: 10.1523/JNEUROSCI.4220-08.2009  0.48
2009 Marongiu R, Spencer B, Crews L, Adame A, Patrick C, Trejo M, Dallapiccola B, Valente EM, Masliah E. Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux. Journal of Neurochemistry. 108: 1561-74. PMID 19166511 DOI: 10.1111/j.1471-4159.2009.05932.x  0.48
2009 Belichenko PV, Kleschevnikov AM, Masliah E, Wu C, Takimoto-Kimura R, Salehi A, Mobley WC. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. The Journal of Comparative Neurology. 512: 453-66. PMID 19034952 DOI: 10.1002/cne.21895  0.92
2009 Crews L, Spencer B, Masliah E. Role of Aβ degrading enzymes in synaptic plasticity and neurogenesis in Alzheimer's disease Current Hypotheses and Research Milestones in Alzheimer's Disease. 3-12. DOI: 10.1007/978-0-387-87995-6_1  0.48
2008 Spencer B, Marr RA, Rockenstein E, Crews L, Adame A, Potkar R, Patrick C, Gage FH, Verma IM, Masliah E. Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice. Bmc Neuroscience. 9: 109. PMID 19014502 DOI: 10.1186/1471-2202-9-109  0.48
2008 Norman JP, Perry SW, Reynolds HM, Kiebala M, De Mesy Bentley KL, Trejo M, Volsky DJ, Maggirwar SB, Dewhurst S, Masliah E, Gelbard HA. HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization. Plos One. 3: e3731. PMID 19009018 DOI: 10.1371/journal.pone.0003731  0.92
2008 Hamilton JM, Salmon DP, Galasko D, Raman R, Emond J, Hansen LA, Masliah E, Thal LJ. Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies. Neuropsychology. 22: 729-37. PMID 18999346 DOI: 10.1037/a0012949  0.92
2008 Crews L, Lentz MR, Gonzalez RG, Fox HS, Masliah E. Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS. Journal of Neurovirology. 14: 327-39. PMID 18780234 DOI: 10.1080/13550280802132840  0.92
2008 Tsigelny IF, Crews L, Desplats P, Shaked GM, Sharikov Y, Mizuno H, Spencer B, Rockenstein E, Trejo M, Platoshyn O, Yuan JX, Masliah E. Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases. Plos One. 3: e3135. PMID 18769546 DOI: 10.1371/journal.pone.0003135  0.48
2008 Fleming SM, Tetreault NA, Mulligan CK, Hutson CB, Masliah E, Chesselet MF. Olfactory deficits in mice overexpressing human wildtype alpha-synuclein. The European Journal of Neuroscience. 28: 247-56. PMID 18702696 DOI: 10.1111/j.1460-9568.2008.06346.x  0.92
2008 Ubhi K, Rockenstein E, Mante M, Patrick C, Adame A, Thukral M, Shults C, Masliah E. Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy. Neuroreport. 19: 1271-6. PMID 18695506 DOI: 10.1097/WNR.0b013e32830b3661  0.52
2008 Crews L, Rockenstein E, Masliah E. Biological transgenic mouse models of Alzheimer's disease. Handbook of Clinical Neurology. 89: 291-301. PMID 18631753 DOI: 10.1016/S0072-9752(07)01227-4  0.48
2008 Doppler E, Rockenstein E, Ubhi K, Inglis C, Mante M, Adame A, Crews L, Hitzl M, Moessler H, Masliah E. Neurotrophic effects of Cerebrolysin in the Mecp2(308/Y) transgenic model of Rett syndrome. Acta Neuropathologica. 116: 425-37. PMID 18600331 DOI: 10.1007/s00401-008-0407-x  0.48
2008 Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. The Journal of Clinical Investigation. 118: 2190-9. PMID 18497889 DOI: 10.1172/JCI33585  0.92
2008 Belinson H, Lev D, Masliah E, Michaelson DM. Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4690-701. PMID 18448646 DOI: 10.1523/JNEUROSCI.5633-07.2008  0.92
2008 Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E. Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4250-60. PMID 18417705 DOI: 10.1523/JNEUROSCI.0066-08.2008  0.48
2008 Habib SL, Michel D, Masliah E, Thomas B, Ko HS, Dawson TM, Abboud H, Clark RA, Imam SZ. Role of tuberin in neuronal degeneration. Neurochemical Research. 33: 1113-6. PMID 18320306 DOI: 10.1007/s11064-007-9558-8  0.92
2008 Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, Golde T, Masliah E, Roberts AR, Bartfai T. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 2681-6. PMID 18272491 DOI: 10.1073/pnas.0712197105  0.92
2008 Bar-On P, Crews L, Koob AO, Mizuno H, Adame A, Spencer B, Masliah E. Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease. Journal of Neurochemistry. 105: 1656-67. PMID 18248604 DOI: 10.1111/j.1471-4159.2008.05254.x  0.48
2008 Leverenz JB, Hamilton R, Tsuang DW, Schantz A, Vavrek D, Larson EB, Kukull WA, Lopez O, Galasko D, Masliah E, Kaye J, Woltjer R, Clark C, Trojanowski JQ, Montine TJ. Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathology (Zurich, Switzerland). 18: 220-4. PMID 18241240 DOI: 10.1111/j.1750-3639.2007.00117.x  0.92
2008 Sharikov Y, Walker RC, Greenberg J, Kouznetsova V, Nigam SK, Miller MA, Masliah E, Tsigelny IF. MAPAS: a tool for predicting membrane-contacting protein surfaces. Nature Methods. 5: 119. PMID 18235431 DOI: 10.1038/nmeth0208-119  0.48
2008 Kawahara K, Hashimoto M, Bar-On P, Ho GJ, Crews L, Mizuno H, Rockenstein E, Imam SZ, Masliah E. alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease. The Journal of Biological Chemistry. 283: 6979-87. PMID 18195004 DOI: 10.1074/jbc.M710418200  0.48
2008 Kanazawa T, Chana G, Glatt SJ, Mizuno H, Masliah E, Yoneda H, Tsuang MT, Everall IP. The utility of SELENBP1 gene expression as a biomarker for major psychotic disorders: replication in schizophrenia and extension to bipolar disorder with psychosis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 686-9. PMID 18163446 DOI: 10.1002/ajmg.b.30664  0.92
2008 Gendelman HE, Masliah E. Innate and adaptive immunity in health and disease Neuroimmune Pharmacology. 7-8. DOI: 10.1007/978-0-387-72573-4_2  0.92
2007 Salaria S, Badkoobehi H, Rockenstein E, Crews L, Chana G, Masliah E, Everall IP. Toll-like receptor pathway gene expression is associated with human immunodeficiency virus-associated neurodegeneration. Journal of Neurovirology. 13: 496-503. PMID 18097881 DOI: 10.1080/13550280701558616  0.92
2007 Spencer B, Rockenstein E, Crews L, Marr R, Masliah E. Novel strategies for Alzheimer's disease treatment. Expert Opinion On Biological Therapy. 7: 1853-67. PMID 18034651 DOI: 10.1517/14712598.7.12.1853  0.48
2007 Alirezaei M, Watry DD, Flynn CF, Kiosses WB, Masliah E, Williams BR, Kaul M, Lipton SA, Fox HS. Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11047-55. PMID 17928446 DOI: 10.1523/JNEUROSCI.2733-07.2007  0.92
2007 Fernagut PO, Hutson CB, Fleming SM, Tetreaut NA, Salcedo J, Masliah E, Chesselet MF. Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression. Synapse (New York, N.Y.). 61: 991-1001. PMID 17879265 DOI: 10.1002/syn.20456  0.92
2007 Rockenstein E, Crews L, Masliah E. Transgenic animal models of neurodegenerative diseases and their application to treatment development Advanced Drug Delivery Reviews. 59: 1093-1102. PMID 17869376 DOI: 10.1016/j.addr.2007.08.013  0.48
2007 Nakashima-Yasuda H, Uryu K, Robinson J, Xie SX, Hurtig H, Duda JE, Arnold SE, Siderowf A, Grossman M, Leverenz JB, Woltjer R, Lopez OL, Hamilton R, Tsuang DW, Galasko D, ... Masliah E, et al. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathologica. 114: 221-9. PMID 17653732 DOI: 10.1007/s00401-007-0261-2  0.92
2007 Wei J, Fujita M, Nakai M, Waragai M, Watabe K, Akatsu H, Rockenstein E, Masliah E, Hashimoto M. Enhanced lysosomal pathology caused by beta-synuclein mutants linked to dementia with Lewy bodies. The Journal of Biological Chemistry. 282: 28904-14. PMID 17652097 DOI: 10.1074/jbc.M703711200  0.52
2007 Kuczenski R, Everall IP, Crews L, Adame A, Grant I, Masliah E. Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat Experimental Neurology. 207: 42-51. PMID 17603040 DOI: 10.1016/j.expneurol.2007.05.023  0.48
2007 Letendre S, Paulino AD, Rockenstein E, Adame A, Crews L, Cherner M, Heaton R, Ellis R, Everall IP, Grant I, Masliah E. Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV. The Journal of Infectious Diseases. 196: 361-70. PMID 17597450 DOI: 10.1086/519285  0.48
2007 Dufty BM, Warner LR, Hou ST, Jiang SX, Gomez-Isla T, Leenhouts KM, Oxford JT, Feany MB, Masliah E, Rohn TT. Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. The American Journal of Pathology. 170: 1725-38. PMID 17456777 DOI: 10.2353/ajpath.2007.061232  0.92
2007 Cherner M, Cysique L, Heaton RK, Marcotte TD, Ellis RJ, Masliah E, Grant I. Neuropathologic confirmation of definitional criteria for human immunodeficiency virus-associated neurocognitive disorders. Journal of Neurovirology. 13: 23-8. PMID 17454445 DOI: 10.1080/13550280601089175  0.92
2007 Tsigelny IF, Bar-On P, Sharikov Y, Crews L, Hashimoto M, Miller MA, Keller SH, Platoshyn O, Yuan JXJ, Masliah E. Dynamics of α-synuclein aggregation and inhibition of pore-like oligomer development by β-synuclein Febs Journal. 274: 1862-1877. PMID 17381514 DOI: 10.1111/j.1742-4658.2007.05733.x  0.48
2007 Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, Dubois B, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, ... ... Masliah E, et al. DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology. 68: 812-9. PMID 17353469 DOI: 10.1212/01.wnl.0000256715.13907.d3  0.92
2007 Rockenstein E, Torrance M, Adame A, Mante M, Bar-on P, Rose JB, Crews L, Masliah E. Neuroprotective effects of regulators of the glycogen synthase kinase-3β signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation Journal of Neuroscience. 27: 1981-1991. PMID 17314294 DOI: 10.1523/JNEUROSCI.4321-06.2007  0.48
2007 Spencer B, Crews L, Masliah E. Climbing the scaffolds of Parkinson's disease pathogenesis. Neuron. 53: 469-70. PMID 17296545 DOI: 10.1016/j.neuron.2007.02.002  0.48
2007 Rockenstein E, Mante M, Adame A, Crews L, Moessler H, Masliah E. Effects of Cerebrolysin™ on neurogenesis in an APP transgenic model of Alzheimer's disease Acta Neuropathologica. 113: 265-275. PMID 17131129 DOI: 10.1007/s00401-006-0166-5  0.48
2007 Zhou X, Qyang Y, Kelsoe JR, Masliah E, Geyer MA. Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant mice. Genes, Brain, and Behavior. 6: 269-76. PMID 16899055 DOI: 10.1111/j.1601-183X.2006.00256.x  0.92
2006 Berman JW, Carson MJ, Chang L, Cox BM, Fox HS, Gonzalez RG, Hanson GR, Hauser KF, Ho WZ, Hong JS, Major EO, Maragos WF, Masliah E, McArthur JC, Miller DB, et al. NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 351-99. PMID 18040811 DOI: 10.1007/s11481-006-9048-9  0.48
2006 Luo J, Lin AH, Masliah E, Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 103: 18326-31. PMID 17110447 DOI: 10.1073/pnas.0605077103  0.92
2006 Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. The Journal of Clinical Investigation. 116: 3060-9. PMID 17080199 DOI: 10.1172/JCI27341  0.92
2006 Chana G, Everall IP, Crews L, Langford D, Adame A, Grant I, Cherner M, Lazzaretto D, Heaton R, Ellis R, Masliah E. Cognitive deficits and degeneration of interneurons in HIV+ methamphetamine users. Neurology. 67: 1486-9. PMID 17060582 DOI: 10.1212/01.wnl.0000240066.02404.e6  0.48
2006 Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science (New York, N.Y.). 314: 130-3. PMID 17023659 DOI: 10.1126/science.1134108  0.92
2006 Mandal PK, Pettegrew JW, Masliah E, Hamilton RL, Mandal R. Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease. Neurochemical Research. 31: 1153-62. PMID 16947080 DOI: 10.1007/s11064-006-9140-9  0.92
2006 Masliah E, Crews L, Hansen L. Synaptic remodeling during aging and in Alzheimer's disease Journal of Alzheimer's Disease. 9: 91-99. PMID 16914848 DOI: 10.3233/JAD-2006-9S311  0.48
2006 Uehara T, Nakamura T, Yao D, Shi ZQ, Gu Z, Ma Y, Masliah E, Nomura Y, Lipton SA. S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature. 441: 513-7. PMID 16724068 DOI: 10.1038/nature04782  0.48
2006 Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, Puoliväli J, Scearce-Levie K, Masliah E, Mucke L. Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5167-79. PMID 16687508 DOI: 10.1523/JNEUROSCI.0482-06.2006  0.92
2006 Moore DJ, Masliah E, Rippeth JD, Gonzalez R, Carey CL, Cherner M, Ellis RJ, Achim CL, Marcotte TD, Heaton RK, Grant I. Cortical and subcortical neurodegeneration is associated with HIV neurocognitive impairment. Aids (London, England). 20: 879-87. PMID 16549972 DOI: 10.1097/01.aids.0000218552.69834.00  0.92
2006 Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E. Cerebrolysin decreases amyloid-β production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease Journal of Neuroscience Research. 83: 1252-1261. PMID 16511867 DOI: 10.1002/jnr.20818  0.48
2006 Webster B, Hansen L, Adame A, Crews L, Torrance M, Thal L, Masliah E. Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 142-51. PMID 16462205 DOI: 10.1097/01.jnen.0000199599.63204.6f  0.48
2005 Shults CW, Rockenstein E, Crews L, Adame A, Mante M, Larrea G, Hashimoto M, Song D, Iwatsubo T, Tsuboi K, Masliah E. Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10689-99. PMID 16291942 DOI: 10.1523/JNEUROSCI.3527-05.2005  0.48
2005 Gilman S, May SJ, Shults CW, Tanner CM, Kukull W, Lee VM, Masliah E, Low P, Sandroni P, Trojanowski JQ, Ozelius L, Foroud T. The North American Multiple System Atrophy Study Group. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 1687-94. PMID 16284910 DOI: 10.1007/s00702-005-0381-6  0.92
2005 Bellizzi MJ, Lu SM, Masliah E, Gelbard HA. Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor. The Journal of Clinical Investigation. 115: 3185-92. PMID 16276420 DOI: 10.1172/JCI25444  0.92
2005 Everall IP, Hansen LA, Masliah E. The shifting patterns of HIV encephalitis neuropathology. Neurotoxicity Research. 8: 51-61. PMID 16260385 DOI: 10.1007/BF03033819  0.68
2005 Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, Mucke L. Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9694-703. PMID 16237174 DOI: 10.1523/JNEUROSCI.2980-05.2005  0.92
2005 Buttini M, Masliah E, Barbour R, Grajeda H, Motter R, Johnson-Wood K, Khan K, Seubert P, Freedman S, Schenk D, Games D. Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9096-101. PMID 16207868 DOI: 10.1523/JNEUROSCI.1697-05.2005  0.92
2005 Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, Gage FH, Verma IM, Masliah E. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nature Neuroscience. 8: 1343-9. PMID 16136043 DOI: 10.1038/nn1531  0.48
2005 Williams K, Westmoreland S, Greco J, Ratai E, Lentz M, Kim WK, Fuller RA, Kim JP, Autissier P, Sehgal PK, Schinazi RF, Bischofberger N, Piatak M, Lifson JD, Masliah E, et al. Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS. The Journal of Clinical Investigation. 115: 2534-45. PMID 16110325 DOI: 10.1172/JCI22953  0.92
2005 Rockenstein E, Mante M, Alford M, Adame A, Crews L, Hashimoto M, Esposito L, Mucke L, Masliah E. High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease. The Journal of Biological Chemistry. 280: 32957-67. PMID 16027115 DOI: 10.1074/jbc.M507016200  0.48
2005 Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, Koo EH. Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation. The American Journal of Pathology. 167: 151-9. PMID 15972961 DOI: 10.1016/S0002-9440(10)62962-8  0.8
2005 Masliah E, Rockenstein E, Adame A, Alford M, Crews L, Hashimoto M, Seubert P, Lee M, Goldstein J, Chilcote T, Games D, Schenk D. Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron. 46: 857-68. PMID 15953415 DOI: 10.1016/j.neuron.2005.05.010  0.48
2005 Chesebro B, Trifilo M, Race R, Meade-White K, Teng C, LaCasse R, Raymond L, Favara C, Baron G, Priola S, Caughey B, Masliah E, Oldstone M. Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science (New York, N.Y.). 308: 1435-9. PMID 15933194 DOI: 10.1126/science.1110837  0.92
2005 Lentz MR, Kim JP, Westmoreland SV, Greco JB, Fuller RA, Ratai EM, He J, Sehgal PK, Halpern EF, Lackner AA, Masliah E, González RG. Quantitative neuropathologic correlates of changes in ratio of N-acetylaspartate to creatine in macaque brain. Radiology. 235: 461-8. PMID 15798152 DOI: 10.1148/radiol.2352040003  0.92
2005 Rockenstein E, Schwach G, Ingolic E, Adame A, Crews L, Mante M, Pfragner R, Schreiner E, Windisch M, Masliah E. Lysosomal pathology associated with α-synuclein accumulation in transgenic models using an eGFP fusion protein Journal of Neuroscience Research. 80: 247-259. PMID 15765523 DOI: 10.1002/jnr.20446  0.48
2005 Green DA, Masliah E, Vinters HV, Beizai P, Moore DJ, Achim CL. Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients. Aids (London, England). 19: 407-11. PMID 15750394 DOI: 10.1097/01.aids.0000161770.06158.5c  0.92
2005 Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science (New York, N.Y.). 307: 1282-8. PMID 15731448 DOI: 10.1126/science.1105681  0.92
2005 Ho GJ, Hashimoto M, Adame A, Izu M, Alford MF, Thal LJ, Hansen LA, Masliah E. Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role. Neurobiology of Aging. 26: 625-35. PMID 15708437 DOI: 10.1016/j.neurobiolaging.2004.06.016  0.48
2005 Rockenstein E, Adame A, Mante M, Larrea G, Crews L, Windisch M, Moessler H, Masliah E. Amelioration of the cerebrovascular amyloidosis in a transgenic model of Alzheimer's disease with the neurotrophic compound Cerebrolysin™ Journal of Neural Transmission. 112: 269-282. PMID 15657642 DOI: 10.1007/s00702-004-0181-4  0.48
2005 Masliah E, Hansen L, Adame A, Crews L, Bard F, Lee C, Seubert P, Games D, Kirby L, Schenk D. Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease. Neurology. 64: 129-31. PMID 15642916 DOI: 10.1212/01.WNL.0000148590.39911.DF  0.48
2005 Zhou X, Long JM, Geyer MA, Masliah E, Kelsoe JR, Wynshaw-Boris A, Chien KR. Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Molecular Psychiatry. 10: 393-406. PMID 15558077 DOI: 10.1038/sj.mp.4001621  0.92
2004 Langford D, Grigorian A, Hurford R, Adame A, Crews L, Masliah E. The role of mitochondrial alterations in the combined toxic effects of human immunodeficiency virus Tat protein and methamphetamine on calbindin positive-neurons Journal of Neurovirology. 10: 327-337. PMID 15765804 DOI: 10.1080/13550280490520961  0.48
2004 Hashimoto M, Kawahara K, Bar-On P, Rockenstein E, Crews L, Masliah E. The role of α-synuclein assembly and metabolism in the pathogenesis of Lewy body disease Journal of Molecular Neuroscience. 24: 343-352. PMID 15655259 DOI: 10.1385/JMN:24:3:343  0.48
2004 Masliah E, Roberts ES, Langford D, Everall I, Crews L, Adame A, Rockenstein E, Fox HS. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis Journal of Neuroimmunology. 157: 163-175. PMID 15579294 DOI: 10.1016/j.jneuroim.2004.08.026  0.48
2004 Achim CL, Masliah E, Schindelar J, Avramut M. Immunophilin expression in the HIV-infected brain. Journal of Neuroimmunology. 157: 126-32. PMID 15579289 DOI: 10.1016/j.jneuroim.2004.08.041  0.92
2004 Belichenko PV, Masliah E, Kleschevnikov AM, Villar AJ, Epstein CJ, Salehi A, Mobley WC. Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome. The Journal of Comparative Neurology. 480: 281-98. PMID 15515178 DOI: 10.1002/cne.20337  0.92
2004 Fleming SM, Salcedo J, Fernagut PO, Rockenstein E, Masliah E, Levine MS, Chesselet MF. Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9434-40. PMID 15496679 DOI: 10.1523/JNEUROSCI.3080-04.2004  0.92
2004 Crews L, Wyss-Coray T, Masliah E. Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models. Brain Pathology (Zurich, Switzerland). 14: 312-6. PMID 15446587  0.48
2004 Hamilton JM, Salmon DP, Galasko D, Delis DC, Hansen LA, Masliah E, Thomas RG, Thal LJ. A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 10: 689-97. PMID 15327716 DOI: 10.1017/S1355617704105043  0.92
2004 Emery SC, Vaux KK, Pretorius D, Masliah E, Benirschke K. Acardiac Twin with Externalized Intestine Adherent to Placenta: Unusual Manifestation of Omphalocele Pediatric and Developmental Pathology. 7: 81-85. PMID 15255039 DOI: 10.1007/s10024-003-5052-8  0.92
2004 Yao D, Gu Z, Nakamura T, Shi ZQ, Ma Y, Gaston B, Palmer LA, Rockenstein EM, Zhang Z, Masliah E, Uehara T, Lipton SA. Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 10810-4. PMID 15252205 DOI: 10.1073/pnas.0404161101  0.92
2004 Licastro F, Chiappelli M, Thal LJ, Masliah E. alpha-1-Antichymotrypsin polymorphism in the gene promoter region affects survival and synapsis loss in Alzheimer's disease. Archives of Gerontology and Geriatrics. Supplement. 243-51. PMID 15207421 DOI: 10.1016/j.archger.2004.04.034  0.92
2004 Takehashi M, Alioto T, Stedeford T, Persad AS, Banasik M, Masliah E, Tanaka S, Ueda K. Septin 3 gene polymorphism in Alzheimer's disease. Gene Expression. 11: 263-70. PMID 15200238 DOI: 10.3727/000000003783992243  0.92
2004 Tiraboschi P, Hansen LA, Masliah E, Alford M, Thal LJ, Corey-Bloom J. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology. 62: 1977-83. PMID 15184600  0.92
2004 Greco JB, Westmoreland SV, Ratai EM, Lentz MR, Sakaie K, He J, Sehgal PK, Masliah E, Lackner AA, González RG. In vivo 1H MRS of brain injury and repair during acute SIV infection in the macaque model of neuroAIDS. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 51: 1108-14. PMID 15170829 DOI: 10.1002/mrm.20073  0.92
2004 Chin J, Palop JJ, Yu GQ, Kojima N, Masliah E, Mucke L. Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4692-7. PMID 15140940 DOI: 10.1523/JNEUROSCI.0277-04.2004  0.92
2004 Tiraboschi P, Sabbagh MN, Hansen LA, Salmon DP, Merdes A, Gamst A, Masliah E, Alford M, Thal LJ, Corey-Bloom J. Alzheimer disease without neocortical neurofibrillary tangles: "a second look". Neurology. 62: 1141-7. PMID 15079014 DOI: 10.1212/01.WNL.0000118212.41542.E7  0.92
2004 Fuller RA, Westmoreland SV, Ratai E, Greco JB, Kim JP, Lentz MR, He J, Sehgal PK, Masliah E, Halpern E, Lackner AA, González RG. A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS. Bmc Neuroscience. 5: 10. PMID 15070430 DOI: 10.1186/1471-2202-5-10  0.48
2004 Kennedy BP, Bottiglieri T, Arning E, Ziegler MG, Hansen LA, Masliah E. Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function. Journal of Neural Transmission (Vienna, Austria : 1996). 111: 547-67. PMID 15057524 DOI: 10.1007/s00702-003-0096-5  0.92
2004 Klucken J, Shin Y, Masliah E, Hyman BT, McLean PJ. Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity. The Journal of Biological Chemistry. 279: 25497-502. PMID 15044495 DOI: 10.1074/jbc.M400255200  0.92
2004 Hashimoto M, Bar-On P, Ho G, Takenouchi T, Rockenstein E, Crews L, Masliah E. β-synuclein regulates Akt activity in neuronal cells: A possible mechanism for neuroprotection in Parkinson's disease Journal of Biological Chemistry. 279: 23622-23629. PMID 15026413 DOI: 10.1074/jbc.M313784200  0.48
2004 Song DD, Shults CW, Sisk A, Rockenstein E, Masliah E. Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP Experimental Neurology. 186: 158-172. PMID 15026254 DOI: 10.1016/S0014-4886(03)00342-X  0.92
2004 Archibald SL, Masliah E, Fennema-Notestine C, Marcotte TD, Ellis RJ, McCutchan JA, Heaton RK, Grant I, Mallory M, Miller A, Jernigan TL. Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss. Archives of Neurology. 61: 369-76. PMID 15023814 DOI: 10.1001/archneur.61.3.369  0.92
2004 Solforosi L, Criado JR, McGavern DB, Wirz S, Sánchez-Alavez M, Sugama S, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah E, Gilden D, Oldstone MB, Conti B, Williamson RA. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science (New York, N.Y.). 303: 1514-6. PMID 14752167 DOI: 10.1126/science.1094273  0.92
2004 Marr RA, Guan H, Rockenstein E, Kindy M, Gage FH, Verma I, Masliah E, Hersh LB. Neprilysin regulates amyloid Beta peptide levels. Journal of Molecular Neuroscience : Mn. 22: 5-11. PMID 14742905 DOI: 10.1385/JMN:22:1-2:5  0.92
2003 Brionne TC, Tesseur I, Masliah E, Wyss-Coray T. Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. Neuron. 40: 1133-45. PMID 14687548 DOI: 10.1016/S0896-6273(03)00766-9  0.92
2003 Lu DC, Shaked GM, Masliah E, Bredesen DE, Koo EH. Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes. Annals of Neurology. 54: 781-9. PMID 14681887 DOI: 10.1002/ana.10761  0.92
2003 Langford D, Adame A, Grigorian A, Grant I, McCutchan JA, Ellis RJ, Marcotte TD, Masliah E. Patterns of selective neuronal damage in methamphetamine-user AIDS patients. Journal of Acquired Immune Deficiency Syndromes (1999). 34: 467-74. PMID 14657756 DOI: 10.1097/00126334-200312150-00004  0.48
2003 Hashimoto M, Rockenstein E, Crews L, Masliah E. Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases Neuromolecular Medicine. 4: 21-35. PMID 14528050 DOI: 10.1385/NMM:4:1-2:21  0.48
2003 Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10966-71. PMID 12939405 DOI: 10.1073/pnas.1434398100  0.92
2003 Palop JJ, Jones B, Kekonius L, Chin J, Yu GQ, Raber J, Masliah E, Mucke L. Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proceedings of the National Academy of Sciences of the United States of America. 100: 9572-7. PMID 12881482 DOI: 10.1073/pnas.1133381100  0.92
2003 Masliah E, Alford M, Adame A, Rockenstein E, Galasko D, Salmon D, Hansen LA, Thal LJ. Abeta1-42 promotes cholinergic sprouting in patients with AD and Lewy body variant of AD. Neurology. 61: 206-11. PMID 12874400 DOI: 10.1212/01.WNL.0000073987.79060.4B  0.48
2003 Samland H, Huitron-Resendiz S, Masliah E, Criado J, Henriksen SJ, Campbell IL. Profound increase in sensitivity to glutamatergic- but not cholinergic agonist-induced seizures in transgenic mice with astrocyte production of IL-6. Journal of Neuroscience Research. 73: 176-87. PMID 12836160 DOI: 10.1002/jnr.10635  0.92
2003 Kennedy BP, Ziegler MG, Alford M, Hansen LA, Thal LJ, Masliah E. Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 110: 789-801. PMID 12811639 DOI: 10.1007/s00702-003-0828-6  0.92
2003 Langford TD, Letendre SL, Larrea GJ, Masliah E. Changing patterns in the neuropathogenesis of HIV during the HAART era Brain Pathology. 13: 195-210. PMID 12744473 DOI: 10.1111/j.1750-3639.2003.tb00019.x  0.48
2003 Marr RA, Rockenstein E, Mukherjee A, Kindy MS, Hersh LB, Gage FH, Verma IM, Masliah E. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1992-6. PMID 12657655  0.92
2002 Cherner M, Masliah E, Ellis RJ, Marcotte TD, Moore DJ, Grant I, Heaton RK. Neurocognitive dysfunction predicts postmortem findings of HIV encephalitis. Neurology. 59: 1563-7. PMID 12451198 DOI: 10.1212/01.WNL.0000034175.11956.79  0.92
2002 Van Uden E, Mallory M, Veinbergs I, Alford M, Rockenstein E, Masliah E. Increased extracellular amyloid deposition and neurodegeneration in human amyloid precursor protein transgenic mice deficient in receptor-associated protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9298-304. PMID 12417655  0.92
2002 Ho GJ, Hansen LA, Alford MF, Foster K, Salmon DP, Galasko D, Thal LJ, Masliah E. Age at onset is associated with disease severity in Lewy body variant and Alzheimer's disease. Neuroreport. 13: 1825-8. PMID 12395133  0.48
2002 Tiraboschi P, Hansen LA, Alford M, Merdes A, Masliah E, Thal LJ, Corey-Bloom J. Early and widespread cholinergic losses differentiate dementia with Lewy bodies from Alzheimer disease. Archives of General Psychiatry. 59: 946-51. PMID 12365882  0.92
2002 Wyss-Coray T, Yan F, Lin AH, Lambris JD, Alexander JJ, Quigg RJ, Masliah E. Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 10837-42. PMID 12119423 DOI: 10.1073/pnas.162350199  0.92
2002 Rockenstein E, Mallory M, Hashimoto M, Song D, Shults CW, Lang I, Masliah E. Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters Journal of Neuroscience Research. 68: 568-578. PMID 12111846 DOI: 10.1002/jnr.10231  0.48
2002 Langford D, Sanders VJ, Mallory M, Kaul M, Masliah E. Expression of stromal cell-derived factor 1alpha protein in HIV encephalitis. Journal of Neuroimmunology. 127: 115-26. PMID 12044982 DOI: 10.1016/S0165-5728(02)00068-1  0.48
2002 Garden GA, Budd SL, Tsai E, Hanson L, Kaul M, D'Emilia DM, Friedlander RM, Yuan J, Masliah E, Lipton SA. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4015-24. PMID 12019321  0.92
2002 Woulfe JM, Duke R, Middeldorp JM, Stevens S, Vervoort M, Hashimoto M, Masliah E, Chan P, Di Monte DA, Langston JW, Petzinger G, Hoogendoorn H, Munoz DG. Absence of elevated anti-alpha-synuclein and anti-EBV latent membrane protein antibodies in PD. Neurology. 58: 1435-6. PMID 12011302 DOI: 10.1212/WNL.58.9.1435  0.92
2002 Langford TD, Letendre SL, Marcotte TD, Ellis RJ, McCutchan JA, Grant I, Mallory ME, Hansen LA, Archibald S, Jernigan T, Masliah E. Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy. Aids (London, England). 16: 1019-29. PMID 11953468 DOI: 10.1097/00002030-200205030-00008  0.92
2002 Rose SC, Behling C, Roberts AC, Pretorius DH, Nelson TR, Kinney TB, Masliah E, Hassanein TI. Main portal vein access in transjugular intrahepatic portosystemic shunt procedures: use of three-dimensional ultrasound to ensure safety. Journal of Vascular and Interventional Radiology : Jvir. 13: 267-73. PMID 11875086 DOI: 10.1016/S1051-0443(07)61719-9  0.92
2002 Veinbergs I, Everson A, Sagara Y, Masliah E. Neurotoxic effects of apolipoprotein E4 are mediated via dysregulation of calcium homeostasis. Journal of Neuroscience Research. 67: 379-87. PMID 11813243 DOI: 10.1002/jnr.10138  0.48
2001 Xia Y, Saitoh T, Uéda K, Tanaka S, Chen X, Hashimoto M, Hsu L, Conrad C, Sundsmo M, Yoshimoto M, Thal L, Katzman R, Masliah E. Characterization of the human alpha-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms. Journal of Alzheimer's Disease : Jad. 3: 485-494. PMID 12214035 DOI: 10.3233/JAD-2001-3508  0.56
2001 Masliah E, Alford M, Galasko D, Salmon D, Hansen LA, Good PF, Perl DP, Thal L. Cholinergic deficits in the brains of patients with parkinsonism-dementia complex of Guam. Neuroreport. 12: 3901-3. PMID 11742207 DOI: 10.1097/00001756-200112210-00009  0.92
2001 Chen Q, Yoshida H, Schubert D, Maher P, Mallory M, Masliah E. Presenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylation. The American Journal of Pathology. 159: 1597-602. PMID 11696419 DOI: 10.1016/S0002-9440(10)63005-2  0.56
2001 Masliah E, Ho G, Wyss-Coray T. Functional role of TGF beta in Alzheimer's disease microvascular injury: lessons from transgenic mice. Neurochemistry International. 39: 393-400. PMID 11578774 DOI: 10.1016/S0197-0186(01)00046-8  0.48
2001 Rockenstein E, Hansen LA, Mallory M, Trojanowski JQ, Galasko D, Masliah E. Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease. Brain Research. 914: 48-56. PMID 11578596 DOI: 10.1016/S0006-8993(01)02772-X  0.68
2001 Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L. beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 12245-50. PMID 11572944 DOI: 10.1073/pnas.211412398  0.48
2001 Veinbergs I, Van Uden E, Mallory M, Alford M, McGiffert C, DeTeresa R, Orlando R, Masliah E. Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E. Experimental Neurology. 170: 15-26. PMID 11421580 DOI: 10.1006/exnr.2001.7684  0.92
2001 Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, McConlogue L, Masliah E, Mucke L. TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nature Medicine. 7: 612-8. PMID 11329064 DOI: 10.1038/87945  0.92
2001 Masliah E, Sisk A, Mallory M, Games D. Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Journal of Neuropathology and Experimental Neurology. 60: 357-68. PMID 11305871 DOI: 10.1093/JNEN/60.4.357  0.92
2001 Everall IP, Trillo-Pazos G, Bell C, Mallory M, Sanders V, Masliah E. Amelioration of neurotoxic effects of HIV envelope protein gp120 by fibroblast growth factor: a strategy for neuroprotection. Journal of Neuropathology and Experimental Neurology. 60: 293-301. PMID 11245213 DOI: 10.1093/JNEN/60.3.293  0.92
2001 Zhukareva V, Vogelsberg-Ragaglia V, Van Deerlin VM, Bruce J, Shuck T, Grossman M, Clark CM, Arnold SE, Masliah E, Galasko D, Trojanowski JQ, Lee VM. Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Annals of Neurology. 49: 165-75. PMID 11220736 DOI: 10.1002/1531-8249(20010201)49:2<165::AID-ANA36>3.0.CO;2-3  0.44
2001 Yeon SW, Jung MW, Ha MJ, Kim SU, Huh K, Savage MJ, Masliah E, Mook-Jung I. Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein. Biochemical and Biophysical Research Communications. 280: 782-7. PMID 11162589 DOI: 10.1006/bbrc.2000.4181  0.92
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